1 Scientific Curriculum Vitae Name: Matthias Schaefer Address: Medical

Scientific Curriculum Vitae

Name: Matthias Schaefer Address: Medical University of Vienna Center for Anatomy and Cell Biology Division of Cell and Developmental Biology Schwarzspanierstrasse 17-I, 1090 Vienna, Austria Phone: +43-1-40160-37702 Email: [email protected] Website: http://bit.ly/1iR5H94 ORCiD 0000-0003-1952-8115

Research Interests Nucleotide modifications, regulatory RNAs, epigenetics, stem cell biology, technology development, biomarker development

Academic Education 2017-present Associate Professor at Medical University Vienna, Vienna, Austria 2015-2017 Assistant Professor at Medical University Vienna, Vienna, Austria 2014-2015 Group Leader at Max-Perutz Laboratories, Vienna, Austria 2014 Venia Legendi in Biochemistry University of Heidelberg, Germany 2008-2014 Project Leader with Dr. Frank Lyko German Cancer Research Center, Heidelberg, Germany 2004-2008 Postdoc with Dr. Frank Lyko German Cancer Research Center, Heidelberg, Germany 2002- 2004 Postdoc with Dr. Jonas Frisén Karolinska Institute, Medical Nobel Institute, Stockholm, Sweden 1998- 2002 Graduate student with Dr. Jürgen A. Knoblich Institute of Molecular Pathology (I.M.P.), Vienna, Austria 1996- 1998 Research associate with Dr. Robert H. Singer Albert-Einstein College of Medicine, New York, USA 1996 Diploma thesis research with Dr. Titia de Lange The Rockefeller University, New York, USA 1991- 1996 Undergraduate studies in Biochemistry, Free University Berlin, Germany

Scholarships and Awards 2002-2004 EMBO Long-Term Fellow

Memberships 2009-2015 DFG FOR 1082 (DFG funded research consortium)

Present International Cooperation Partners Stefanie Kellner, Ludwig-Maximilians-Universität München, Germany; Mass spectrometry of nucleic acid modifications. Albert Jeltsch, University of Stuttgart, Germany; Effects of paternal RNAs on epigenetic mechanisms in the early zygote. Isidore Rigoutsos, Thomas Jefferson University, USA; Bioinformatic identification and mapping of tRNA fragments.

Past International Cooperation Partners Gregory Hannon, Cold Spring Harbor Labs; USA; DNA methylation in Drosophila. Mark Helm, University of Mainz, Germany; Modification status of tRNAs in eukaryotes. Yuri Motorin, University of Lorraine, France; Modification status of rRNAs in yeast. Sarah Cherry, University of Pennsylvania, USA; Virus control in Drosophila. Ody Sibon, University of Groningen, The Netherlands; Influence of DNA methylation on replication stress. Martin Kos, University of Heidelberg, Germany; Impact of RNA modifications on ribosome function in yeast. Michaela Frye, University of Cambridge, UK; Characterization of the RNA methyltransferase NSun2 in the mouse. Yukiko Yamashita, University of Michigan, USA; Dnmt2/Trdmt1 function in the Drosophila germ line.

Invitations as Conference Speaker (5 most important) 2018 The Epitranscriptome/Germany 2015 RNA and Disease/Austria 2014 RNA Biochemistry Meeting/Germany 2012 EMBO Meeting Nice/France 2011 Fourth Weissenburg Symposium – Biriciana/Germany

Ad hoc Journal Referee Bioessays, Cell Reports, EMBO Reports, EMBO Journal, Epigenomics, FEBS Letters, Genomics, Nature Communications, Nature Reviews Molecular Cell Biology, Nucleic Acids

Research, Oncogene, PLoS ONE, PLoS Genetics, RNA Biology, Scientific Reports, Science Advances, WIREs RNA

Grant Review for Funding Agencies Israel Science Foundation (ISF), Medical Research Council (MRC), Austrian Science Foundation (FWF), Boehringer-Ingelheim Foundation (BIF), The Netherlands Organisation for Health Research and Development (ZonMw)