From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 27, 2015 Date: Friday, February 27, 2015 11:22:47 AM Attachments: ATT00001.txt

In the News February 27, 2015

Inquisitr – February 26 New Study on ‘Breakthrough’ Atopic Dermatitis Drug Indicates ‘Eczema Is An Autoimmune Disease’ Researchers behind a new study on the atopic dermatitis drug “dupilumab” (which is currently in trials) say that they have proven that this form of eczema is an autoimmune disease. The potential atopic dermatitis medication blocks the activity of two key immune proteins, interleukin-4 (IL-4) and interleukin-13 (IL-13), and according to the researchers, can reverse the immune response within an allergic individual that causes the atopic dermatitis skin problems. The promising new atopic dermatitis drug study was led by Emma Guttman-Yassky, MD, associate professor of dermatology at the Icahn School of Medicine at Mount Sinai in New York. - Dr. Emma Guttman-Yassky, Associate Professor, Medicine, Dermatology, Clinical Immunology, Icahn School of Medicine at Mount Sinai Learn more: http://www.inquisitr.com/1876764/atopic-dermatitis-drug-autoimmune-disease/

Melty Food (France) – February 27 Chocolate, Pizza, Fries: True Drugs? If you too cannot help but finish a chocolate bar, it’s normal. According to a study by the University of Michigan and the Faculty of Medicine at Mount Sinai Hospital (New York), some foods can be addictive just like a drug . Among the most addictive, there is the top of the charts chocolate, pizza and fries. Processed products, which are added fats and refined sugars operate biological and behavioral responses due to strong artificial pleasure they provide. According to Nicole Avena, co-author of the study, this is "a first step in the identification of specific foods and their properties that can generate addictive behaviors. This could change the way we treat obesity.” - Nicole Avena, PhD, Assistant Professor, Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai Learn more: http://www.meltyfood.fr/chocolat-pizza-frites-de-vrais-drogues-a385658.html [Article is in French] Additional Coverage: Detik Food: http://food.detik.com/read/2015/02/27/064554/2844451/900/gula-dalam-fast-food-membuat- kecanduan-8-kali-lebih-besar-dari-obat-terlarang?d992202284 [Article is in Indonesian] Impronta Unika: http://www.improntaunika.it/2015/02/cibi-spazzatura-sono-come-la-droga- sviluppano-dipendenza/ [Article is in Italian] AGI: https://www.agi.it/salute/notizie/ricerca_cibo_spazzatura_sviluppa_dipendenza_come_droga- 201502261850-hpg-rsa1020 [Article is in Italian] Mondiali Brasile: http://mondialibrasile.com/cioccolato-patatine-e-pizza-come-fumo-alcol-e-droga- 41376 [Article is in Portuguese] Epoch Times: http://www.epochtimes.com/b5/15/2/26/n4374936.htm [Article is in Chinese]

Clinical Pain Advisor – January 2015 Acute Pain: Treating Objectively and Effectively Acute pain, by its nature, requires a careful approach. It starts with the understanding that people of different genders, ages, races, and dispositions experience pain differently. Ula Hwang, MD, associate professor of emergency medicine at the Icahn School of Medicine at Mount Sinai is the lead author of a 2014 study published in the journal Pain. She says, “Across all settings, whether it be a doctor's office or an emergency room, acute pain is treated differently. Women and minorities get less analgesics and opiates. In our study we found that age also changes the way acute pain is treated.” Dr. Hwang says pain is subjective, adding “We don't want the pendulum to swing back to under-treatment of pain...Some people are highly functional with pain, and some are not. When duration and impact of pain become a quality of life issue, it is time for a chronic pain referral” -Dr. Ula Hwang, Associate Professor, Emergency Medicine, Associate Professor Geriatrics and Palliative Medicine, the Icahn School of Medicine at Mount Sinai Learn more: http://www.clinicalpainadvisor.com/meeting-the-challenge-of-acute-pain/article/395313/

Crain’s Health Pulse – February 27 Cardiac Care Deal for Sinai Like many New Yorkers during this cold winter, The Mount Sinai Hospital is heading to Florida: It just signed a partnership with Jupiter Medical Center to create the Mount Sinai Heart New York at Jupiter Medical Center, with Dr. Gonzalo Loveday as its medical director. The Mount Sinai deal covers most facets of cardiac care. Plenty of Mount Sinai heart patients visit Florida in winter—as do the hospital’s doctors and executives, a trend that forged relationships between the hospitals. Arthur Klein, MD, president of the Mount Sinai Health Network, called the partnership “an integral step in providing access and continuity of care for our patients who … split their time between New York and south Florida.” - Dr. Arthur Klein, President, the Mount Sinai Health Network Learn more: http://www.crainsnewyork.com/article/20150227/PULSE/150229883/cannabis-toothpaste- coming-this-year

KFSM – February 26 Healthwatch: Peanut Allergies A new study suggests many peanut allergies can be prevented. Researchers say their findings could lead to major changes in food allergy guidelines. The findings published in the New England Journal of Medicine found introducing peanut early dramatically decreased the risk of developing a peanut allergy. Hugh Sampson, MD, at The Mount Sinai Hospital says this is a landmark study that should change food allergy guidelines. “I think we will now see the prevalence of peanut allergy in this young population start to drop instead of continuing to increase the way we have seen over the last 10 to 15 years.” - Dr. Hugh Sampson, Professor, Pediatrics, Allergy and Immunology, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai Learn more: http://5newsonline.com/2015/02/26/healthwatch-peanut-allergies/

Yale Daily News – February 26 Branford Genomics Facility Expands Four months after its opening, the Mount Sinai Genetic Testing Lab — located in Branford, Connecticut and run by the Icahn School of Medicine at Mount Sinai — is on track to meet its growth targets for the year. “We want to find new ways to identify mechanisms of disease and new ways to improve patient outcomes,” said Todd Arnold, managing director of the Mount Sinai Genetic Testing Lab. Andrew Kasarskis, co-director of the Icahn Institute for Genomics and Multiscale Biology, said Mount Sinai considered numerous options in both the New York-New Jersey area and in Connecticut when deciding where to locate the sequencing facility. -Andrew Kasarkis, PhD, Associate Professor, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Co-Director, Icahn Institute for Genomics and Multiscale Biology - Todd E. Arnold, PhD, Managing Director, The Mount Sinai Genetic Testing Laboratory - Connecticut Learn more: http://yaledailynews.com/blog/2015/02/26/branford-genomics-facility-expanding/

The Chicago Tribune via Healthday – February 26 Fluoride in Drinking Water Tied to Higher Rates of Underactive Thyroid – Alan Mozes A British study finds a correlation between the amount of fluoride in public drinking water and a rise in incidence of underactive thyroid. "This dramatic increase in thyroid dysfunction associated with fluoridation of the water supply adds to previous studies indicating that fluoride has an inhibitory effect on the thyroid gland," said Terry Davies, MD, a professor of medicine at the Icahn School of Medicine at Mount Sinai, in New York City. - Dr. Terry Davies, Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://www.chicagotribune.com/lifestyles/health/sc-hlth-0304-fluoride-underactive-thyroid- 20150226-story.html

USA Today via The Associated Press – February 26 Bulls Say Rose To Have Surgery On Friday The Chicago Bulls are optimistic Derrick Rose will suit up again this season and that surgery Friday on his right knee won't sideline him the rest of the way. The organization sounded upbeat that the procedure to repair a medial meniscus tear won't prevent the star point guard from suiting up again this season. The procedure comes with a shorter recovery period — about six weeks — than a reattachment but an increased risk of arthritis, according to Alexis Colvin, MD, an orthopedic surgeon specializing in sports medicine at New York's The Mount Sinai Hospital. Colvin, who has not examined Rose, said it could take longer for someone with a previous tear to recuperate. -Dr. Alexis Colvin, Associate Professor, Orthopaedics, Icahn School of Medicine at Mount Sinai Learn more: http://www.usatoday.com/story/sports/nba/2015/02/26/bulls-say-rose-to-have-surgery-on- friday/24081317/

Yahoo Beauty – February 26 Celebrities Drive a 98% Increase in Butt Implants – Sara Bliss Celebrities have the power to sell almost everything, but it is still shocking that they are also motivating people to visit the plastic surgeon’s office—in droves. Data from the American Society of Plastic Surgeons released today highlights some surprising trends—an almost 100% surge in butt augmentation in the past year, and a huge increase in minimally invasive, procedures, even in male patients. According to the American Society of Plastic Surgery, male breast reduction is a procedure that has increased 29% from 2000 to 2013. “Just yesterday half of my patients were male,” explains dermatologist Gary Goldenberg, MD. “A lot of men who are older are competing for jobs with much younger men. So I’ve seen an increase in laser, Botox, a facial shaping, like fixing sagging along jowls and creating a nice straight angular jaw by injecting Radiesse.” - Dr. Gary Goldenberg, Assistant Professor, Dermatology, Pathology, Icahn School of Medicine at Mount Sinai Learn more: https://www.yahoo.com/beauty/celebrities-drive-98-increase-in-butt-implants- 112165342143.html

Deccan Herald via The New York Times– February 27 The Pillow Cure – Penelope Green For years, the standard pillow for those with neck issues has been a crudely formed foam number, which is about as sexy as the cervical collar that is its daytime mate. In 2012, 14 percent of adult Americans said they had neck pain within a three-month period; in 2010, another survey noted that there were more than 10 million visits to doctors’ offices for complaints related to neck pain. As it turns out, said Robert Gotlin, MD, director of orthopedic and sports rehabilitation at Mount Sinai Beth Israel, we are designed for failure. “The fact is, from age 25 on, this process of failure begins,” he continued cheerfully. As far as pillows are concerned, he said: “The real answer is, there is no answer. - Dr. Robert Gotlin, Associate Professor, Rehabilitation Medicine, Orthopaedics, Icahn School of Medicine at Mount Sinai, Director, Orthopaedic and Sports Rehabilitation, Mount Sinai Beth Israel Learn more: http://www.deccanherald.com/content/462236/pillow-cure.html

Herald (Ireland) – February 27 Don't Shower Every Day? Well, You're Still Healthier than Most – Colette Fitzgerald They call it a birdy bath -when you don't have a full bath or shower but wash the hotspots, as it were. Or you have a student shower, when baby wipes or a facecloth are used for those areas that need extra attention. But because we live in a society obsessed with artificial cleanliness, if you admit that you don't shower at least once a day you risk being shunned. Ironically, all this showering and scrubbing is not as healthy as the companies who manufacture shower gels and soaps would have you believe. Joshua Zeichner, MD, Professor of Dermatology at The Mount Sinai Hospital in New York City says that what we perceive as body odor is really "more of a cultural phenomenon". - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.herald.ie/opinion/colette-fitzpatrick-dont-shower-every-day-well-youre-still- healthier-than-most-31025166.html

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 26, 2015 Date: Thursday, February 26, 2015 12:54:09 PM Attachments: ATT00001.txt

In the News February 26, 2015

Medscape – February 25 Insulinlike Growth Factor Promising for Rare Autism Type – Pauline Anderson Insulinlike growth factor–1 (IGF-1) is safe, effective, and significantly improves social withdrawal in children with a rare type of autism spectrum disorder (ASD) but may also have treatment implications for other ASDs, early research suggests. Known as Phelan-McDermid syndrome (PMS), it affects about 1200 individuals worldwide. A treatment for this rare form of autism could have relevance for the treatment of other ASDs, the study's lead author, Alexander Kolevzon, MD, clinical director, Seaver Autism Center, and associate professor of psychiatry and pediatrics, Icahn School of Medicine at Mount Sinai, New York City, told Medscape Medical News. "Studies have already shown that IGF-1 is somewhat effective in Rett syndrome, and now it's been shown to be somewhat effective in PMS," he said. -Dr. Alexander Kolevzon, Assoicate Professor, Psychiatry, Pediatrics, Icahn School of Medicine at Mount Sinai, Clinical Director, Seaver Autism Center at Mount Sinai Learn more: http://www.medscape.com/viewarticle/840414

Columbia Daily Herald via The Seattle Times – February 26 How A Skin Patch Could Be Safe Treatment For Peanut Allergies – JoNel Aleccia A skin patch that experts say could be a breakthrough treatment for peanut-allergy sufferers appears to be both safe and effective, according to an early stage clinical trial that involved Seattle-area children, among others, to test the potentially lifesaving technology. The Viaskin Peanut patch made by the French biotech firm DBV Technologies boosted the amount of peanut protein it took to elicit an allergic reaction by at least 10-fold, particularly in kids younger than 12. The 250-microgram patch, the highest dose, was the most effective, according to the study led by Hugh Sampson, MD, a professor of pediatric allergy and immunity at The Mount Sinai Hospital in New York. - Dr. Hugh Sampson, Professor, Pediatrics, Allergy and Immunology, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai Learn more: http://columbiadailyherald.com/lifestyles/celebrations/how-skin-patch-could-be-safe-treatment-peanut-allergies

The New York Times – February 25 Deep Sympathy for Derrick Rose, the Bulls’ Star-Crossed Star – Andrew Keh The cloud of uncertainty that had engulfed Derrick Rose of the Chicago Bulls since 2012 was beginning to recede. Then came the news late Tuesday night that Rose would need his third major knee operation in less than three years. The injury, the Bulls said, was a torn medial meniscus in his right knee, the same injury that cut short his 2013-14 season after only 10 games. James Gladstone, MD, co-chief of sports medicine at the Icahn School of Medicine at Mount Sinai in Manhattan, said medical research suggested that a repaired meniscus had up to a 30 percent chance of being torn a second time. “More than anything else, he plays a sport that makes him and anyone else who plays in the way he does prone to injury,” Gladstone said. - Dr. James Gladstone, Associate Professor, Orthopaedics, Sports Medicine Service, Icahn School of Medicine at Mount Sinai, Co-Chief, Sports Medicine, The Mount Sinai Hospital Learn more: http://www.nytimes.com/2015/02/26/sports/basketball/for-derrick-rose-another-knee-surgery-is-another-loss.html? _r=2&gwh=99C9B36B82914444490D802A6934F22A&gwt=pay

ABC News via The Associated Press – February 25 Latest Injury to Rose Hits Bulls Hard – Andrew Seligman The news that Derrick Rose will have knee surgery again hit the Chicago Bulls and their fans hard and left them in a familiar spot — trying to get by without their star point guard. The torn meniscus in his right knee was announced Tuesday night, another tough twist for a franchise, a star, his sponsors and a fanbase that thought the Bulls were entering another golden era just a few years ago, with the Chicago product leading the renaissance. Alexis Colvin, MD, an orthopedic surgeon specializing in sports medicine at the Icahn School of Medicine at New York's The Mount Sinai Hospital, said he could have the torn cartilage reattached or removed. -Dr. Alexis Colvin, Associate Professor, Orthopaedics, Icahn School of Medicine at Mount Sinai Learn more: http://abcnews.go.com/Sports/wireStory/latest-injury-rose-hits-bulls-hard-29219658 Additional Coverage: Yahoo Sports: http://sports.yahoo.com/news/latest-injury-rose-hits-bulls-hard-182200915--nba.html Miami Herald: http://www.miamiherald.com/sports/article11143196.html TSN: http://www.tsn.ca/rose-s-injury-hits-bulls-hard-1.215894

ABC News – February 24 Why My Husband's Heart Attack Shouldn't Have Been a Shock – Sandra Temko When I got to Mount Sinai St. Luke’s and Roosevelt Hospital in Manhattan, I learned that my husband Sean had had a massive heart attack and would need a stent to open up the blocked artery. If you think having a heart attack in your forties is unusual, think again. Heart attack risk increases with age, but the American Heart Association stresses that heart attack prevention should begin at age 20. "It’s not like you can regularly eat cheeseburgers and then shut it off at 40," Sean's doctor, Jacqueline Tamis-Holland, MD, at Mount Sinai St. Luke’s and Roosevelt, told me later. "You see the stages of early plaque buildup even in people in their teens." - Dr. Jacqueline Tamis-Holland, Assistant Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai Learn more: http://abcnews.go.com/Health/husbands-heart-attack-shock/story?id=29187511

Healthday – February 25 Fluoride in Drinking Water Tied to Higher Rates of Underactive Thyroid – Alan Mozes A British study finds a correlation between the amount of fluoride in public drinking water and a rise in incidence of underactive thyroid. "This dramatic increase in thyroid dysfunction associated with fluoridation of the water supply adds to previous studies indicating that fluoride has an inhibitory effect on the thyroid gland," said Terry Davies, MD, a professor of medicine at the Icahn School of Medicine at Mount Sinai, in New York City. - Dr. Terry Davies, Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/general-health-information-16/thyroid-news-659/fluoride-in-drinking-water-tied-to-higher-rates-of- underactive-thyroid-696704.html Additional Coverage: U.S. News & World Report: http://health.usnews.com/health-news/articles/2015/02/25/fluoride-in-drinking-water-tied-to-higher-rates-of- underactive-thyroid Philly.com: http://www.philly.com/philly/health/HealthDay696704_20150225_Fluoride_in_Drinking_Water_Tied_to_Higher_Rates_of_Underactive_Thyroid.html International Business Times – February 25 Warren Buffett Drinks 5 Cokes a Day, Eats like a Child to Stay Young – Cristina Silva Warren Buffett drinks five cokes a day and eats like a child. The Berkshire Hathaway CEO said his unhealthy diet is highly strategic. High rates of soda consumption are associated with numerous health problems, such as obesity, poor dental health, diabetes and cardiovascular disease. “The main thing is excess calories,” Christopher Ochner, PhD, assistant professor of pediatrics and adolescent medicine at the Icahn School of Medicine at Mount Sinai, told FoxNews.com. “If everything else in their diet is equal, a person who has a can of Coke a day adds an extra 14.5 pounds per year, just from the calories alone.” -Christopher Ochner, PhD, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.ibtimes.com/warren-buffett-drinks-5-cokes-day-eats-child-stay-young-1829248

Marie Claire – February 25 Celebrities Swear by It, But Is Waist Training Actually Healthy? – Kenny Thapoung Waist training involves wearing a corset-like contraption (yes, like the ones from the 1500s) to cinch your core, hips, and back. The idea is to wear it for a certain amount of time every day, and eventually, your body "molds" itself into a slimmer figure. Should you try it? Well...probably not. When you wear this 500-year-old device, you squish your lungs and ribs, which makes it hard to breathe. (Duh.) Some women have actually passed out from wearing one for too long, says Christopher Ochner, PhD, weight loss and nutrition expert at The Mount Sinai Hospital. -Christopher Ochner, PhD, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.marieclaire.com/health-fitness/a13489/celebrities-swear-by-it-but-is-waist-training-actually-healthy/

Shape – February 25 Scientists Introduce an Anti-Aging Chocolate Bar – Kelly Mickle Scientists at a UK-based company with ties to Cambridge University have created Esthechoc, a 70 percent dark chocolate enriched with cocoa polyphenols and a potent algae extract. Dubbed the first ever “beauty” chocolate, the creators claim it has the power to slow aging, boosting circulation, oxygenation and detoxification to keep skin looking up to 30 years younger. “While these early reports are exciting, additional clinical trials must be performed to confirm the results,” says Joshua Zeichner, MD, director of cosmetic and clinical research in dermatology at The Mount Sinai Hospital in New York City. - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.shape.com/lifestyle/beauty-style/scientists-introduce-anti-aging-chocolate-bar

SheKnows – February 24 6 Ways Binge-Watching TV Is Waging War On Your Body – Kristen Fischer A study last year found that watching television was linked to binge-eating. So, you may sit down to watch your favorite show and wind up eating more than you’d like. Some ideas to combat that are to portion out healthier foods or to rule out eating while you watch television. Christopher Ochner, PhD, an obesity and nutrition expert at The Mount Sinai Hospital in New York City, said binge-watching makes us sedentary so we burn fewer calories than we would if we were walking around or even standing. "If we do this [stay sedentary] often enough, we will actually begin to lose muscle mass, which will be replaced by fat," he said. -Christopher Ochner, PhD, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.sheknows.com/health-and-wellness/articles/1072537/effects-of-watching-too-much-tv

Women Health – February 24 Age-Related Macular Degeneration: a Frustrating Condition to Live with and Treat If you’re over 50 years old and have blurry or wavy vision and/or a blind spot in the center of your vision, you may have Age-Related Macular Degeneration (AMD). Most AMD starts as the dry type, says Robin N. Ginsburg, MD, assistant professor in the Department of Ophthalmology, Mount Sinai Health System. “In 10-20 percent of individuals, it progresses to the wet type.” -Dr. Robin N. Ginsburg, Assistant Professor, Ophthalmology, Icahn School of Medicine at Mount Sinai, Director of the Vitreoretinal Service, The Mount Sinai Hospital Learn more: http://womenshealth.com/age-related-macular-degeneration-a-frustrating-condition-to-live-with-and-treat/

New Beauty – February 25 Can You Really Shrink Your Pores? – Margaret McGriff Uneven skin and acne are part of the beauty challenges those of us with large pores have to deal with. Getting them down to a size where we can keep oiliness at bay and enjoy younger- and brighter-looking skin is the definite answer. But, can we really shrink our pores? The short answer is no, and here’s why. Factors such as genetics and age determine how large your pores are. “Someone's pore size is genetically predetermined and cannot be changed permanently”, explains New York dermatologist Gary Goldenberg, MD. But, all is not lost because there are ways to minimize their appearance. - Dr. Gary Goldenberg, Assistant Professor, Dermatology, Pathology, Icahn School of Medicine at Mount Sinai Learn more: http://www.newbeauty.com/blog/dailybeauty/8418-can-you-shrink-your-pores/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 25, 2015 Date: Wednesday, February 25, 2015 11:35:09 AM Attachments: ATT00001.txt

In the News February 25, 2015

Today Health – February 22 Skin Patch May Protect Against Life-Threatening Peanut Allergy – Linda Carroll In the second phase of a drug trial, half of participants wearing the highest dose “peanut patches” for a year were able to consume the equivalent of four peanuts without reacting, researchers reported Sunday at the annual meeting of the American Academy of Allergy, Asthma, and Immunology. It means that “they are not going to have to worry about traces of peanut in a package that came from a plant where peanuts were used or minor contamination of food in a restaurant,” said the study’s lead author, Hugh Sampson, MD, a professor of pediatrics at the Icahn School of Medicine and director of the Jaffe Food Allergy Institute at Mount Sinai. - Dr. Hugh Sampson, Professor, Pediatrics, Allergy and Immunology, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai Learn more: http://www.today.com/health/peanut-patch-may-protect-against-life-threatening-allergy- 2D80506626 Additional Coverage: The New York Daily News: http://www.nydailynews.com/news/national/eating-peanuts-early-reduce- infants-allergy-chances-article-1.2126463 Clinical Advisor: http://www.clinicaladvisor.com/skin-patch-improves-peanut-tolerance-in-those-with- allergy/article/399717/ Jacksonville Daily News: http://www.jdnews.com/features/health/how-a-skin-patch-could-be-safe- treatment-for-peanut-allergies-1.442587

NPR – February 23 Feeding Babies Foods with Peanuts Appears to Prevent Allergies – Rob Stein Babies at high risk for becoming allergic to peanuts are much less likely to develop the allergy if they are regularly fed foods containing the legumes starting in their first year of life. Specialists say for most parents, the new findings should encourage them to start feeding their kids peanuts as early as possible. "This is a question we get asked constantly in our clinic. When parents come in, they often have young children. They want to know what they should do. This really provides us with the answer," says Hugh Sampson, MD, who heads the Jaffe Food Allergy Institute at Mount Sinai in New York. Sampson co- authored an editorial being published with the study. "This is a major study — really what we would call a landmark study," says Scott Sicherer, MD, who advises the American Academy of Pediatrics on allergies. - Dr. Hugh Sampson, Professor, Pediatrics, Allergy and Immunology, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai - Dr. Scott Sicherer, Elliot and Roslyn Jaffe Professorship in Pediatric Allergy and Immunology, Icahn School of Medicine at Mount Sinai Learn more: http://www.npr.org/blogs/thesalt/2015/02/23/388450621/feeding-babies-foods-with-peanuts- appears-to-prevent-allergies Additional Coverage: The Atlantic: http://www.theatlantic.com/health/archive/2015/02/is-it-really-safe-to-give-babies-peanut- butter/385892/ The Times of India: http://timesofindia.indiatimes.com/home/science/Early-peanut-intake-could- prevent-allergy/articleshow/46363907.cms Popsugar: http://www.popsugar.com/moms/Eating-Peanuts-Reduces-Peanut-Allergy-Risk-36947332 Mashable: http://mashable.com/2015/02/24/eating-peanuts-reduce-risk-study/ Mother Nature Network: http://www.mnn.com/health/allergies/stories/early-exposure-to-peanuts- could-prevent-allergy

Web MD – February 23 Babies Who Eat Peanuts Early May Avoid Allergy A groundbreaking new study determined that after 5 years, children who ate peanut snacks on a regular basis were far less likely to be allergic to them than those that didn’t. “It’s a major landmark study,” says Scott Sicherer, MD, a professor of pediatrics, allergy and immunology at The Mount Sinai Hospital in New York City. In a second study, scientists have figured out how to deliver immunotherapy through the Viaskin skin patch. “This is a new way to deliver immunotherapy,” says study author Hugh Sampson, MD, a pediatric allergist at the Icahn School of Medicine at Mount Sinai. - Dr. Hugh Sampson, Professor, Pediatrics, Allergy and Immunology, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai - Dr. Scott Sicherer, Elliot and Roslyn Jaffe Professorship in Pediatric Allergy and Immunology, Icahn School of Medicine at Mount Sinai Learn more: http://www.webmd.com/allergies/news/20150220/child-peanut-allergy-findings

Medical Xpress – February 24 An Evolutionary Approach Reveals New Clues toward Understanding the Roots of Schizophrenia Is mental illness simply the evolutionary toll humans have to pay in return for our unique and superior cognitive abilities when compared to all other species? But if so, why have often debilitating illnesses like schizophrenia persisted throughout human evolutionary history when the affects can be quite negative on an individual's chances of survival or reproductive success? In a new study appearing in Molecular Biology and Evolution, The Mount Sinai Hospital researcher Joel Dudley has led a new study that suggests that the very changes specific to human evolution may have come at a cost, contributing to the genetic architecture underlying schizophrenia traits in modern humans. - Dr. Joel Dudley, Assistant Professor, Genetics and Genomic Sciences, Population Health Science Policy, Icahn School of Medicine at Mount Sinai Learn more: http://medicalxpress.com/news/2015-02-evolutionary-approach-reveals-clues-roots.html

Healthday – February 24 Skin Test for Alzheimer's, Parkinson's Shows Early Promise – Robert Preidt A small, early study hints that a skin test may someday be able to help diagnose people with Alzheimer's and Parkinson's diseases. Researchers found that skin biopsies can reveal elevated levels of abnormal proteins associated with the two disorders. The study is being released ahead of its presentation in April at the annual meeting of the American Academy of Neurology (AAN) in Washington, D.C. Experts said such a test would be welcome, but it's too early to confirm the usefulness of this skin-based method. They also note that studies presented at medical meetings are typically considered preliminary until published in a peer-reviewed journal. "Similar claims [for diagnostic tests] have been made for a decade or more, but none have held up to scrutiny or independent replication," said Samuel Gandy, MD, associate director of the Alzheimer's Disease Research Center at Mount Sinai, in New York City. - Dr. Samuel Gandy, Professor, Neurology, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/cognitive-health-information-26/alzheimer-s-news-20/skin- test-for-alzheimer-s-parkinson-s-shows-early-promise-696467.html Additional Coverage: Science World Report: http://www.scienceworldreport.com/articles/22708/20150224/could-a-skin-test- give-hints-about-parkinsons-alzheimers-disease.htm

Crain’s Health Pulse – February 25 Sinai, Bronx-Lebanon Deal The Mount Sinai Health System and Bronx-Lebanon Hospital announced a clinical collaboration, yet another example of the cross-border deals that have been reshaping health care. The two will remain independent. Among the areas of cooperation, they plan shared resources as part of DSRIP, as well as a clinically integrated physician network. The two also will establish new clinical programs and services in such areas as cardiology, oncology, surgery, orthopedics and pediatrics, according to a statement. - The Mount Sinai Health System Learn more: http://www.crainsnewyork.com/article/20150225/PULSE/150229933/manhattan-nonprofit- rebrands-amid-growth-spurt#

Daily Burn – February 24 The Low-FODMAP Diet: Your Solution to a Healthier Gut? – Alex Orlov A 2013 study published in the journal Gastroenterology revealed that individuals with non-celiac gluten sensitivity could benefit greatly from omitting FODMAPS-rich foods from their diets. “This was a very impressive study,” says Gina Sam, MD, MPH Director of the Mount Sinai Gastrointestinal Motility Center at the Mount Sinai Hospital. Though there were only 37 participants, the results were remarkable enough for the medical community to take notice. “Patients on the low-FODMAPs diet had dramatic improvements in pain, bloating and stool consistency,” she says. - Dr. Gina Sam, Assistant Professor, Medicine, Gastroenterology, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Gastrointestinal Motility Center at the Mount Sinai Hospital Learn more: http://dailyburn.com/life/health/low-fodmap-diet-digestive-health/

Business Insider – February 24 How to Keep Your High Heels from Killing Your Feet – Portia Crowe Wearing high heels every day can suck. But we have good news: according to Paul Greenberg, MD, a board-certified podiatric surgeon at The Mount Sinai Hospital and Belvedere Podiatry Group, "It's a myth that high heels are bad for your feet." Dr. Greenberg diagnoses and treats a range of foot problems, and the majority of his clients are working professional women. So when it comes to high heels, Greenberg is a realist. Instead, Greenberg laid out some simple tips to make wearing high heels a better experience. - Dr. Paul M. Greenberg, Attending, Department of Surgery, Mount Sinai St. Luke’s Roosevelt Learn more: http://www.businessinsider.com/the-lowdown-on-high-heels-2015-2

First for Women Magazine – February 24 Doctors’ Cures for Winter Skin Woes Months of cold, harsh weather has left you child’s delicate skin dry, itchy and winter-worn. So we asked doctors for the natural remedies they use to heal their own kids’ seasonal skin problems. “My daughter tends to get itchy skin in the winter, especially when the dry heat is pumping throughout our apartment,” says father-of-two Gary Goldenberg, MD, an assistant professor of dermatology and pathology at the Icahn School of Medicine at Mount Sinai in New York City. “I always try over-the- counter or natural treatments first, and one of my favorites is vitamin E oil.” - Dr. Gary Goldenberg, Assistant Professor, Dermatology, Pathology, Icahn School of Medicine at Mount Sinai Learn more: No Web Link Available

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 24, 2015 Date: Tuesday, February 24, 2015 11:51:04 AM Attachments: ATT00001.txt

In the News February 24, 2015

The New York Times – February 23 Feeding Infants Peanut Products Could Prevent Allergies, Study Suggests – Andrew Pollack Turning what was once conventional wisdom on its head, a new study suggests that many, if not most peanut allergies can be prevented by feeding young children food containing peanuts beginning in infancy, rather than avoiding such foods. An editorial published Monday in The New England Journal of Medicine, along with the study, called the results “so compelling” and the rise of peanut allergies “so alarming” that guidelines for how to feed infants at risk of peanut allergies should be revised soon. The study “clearly indicates that the early introduction of peanut dramatically decreases the risk of development of peanut allergy,” said the editorial, by Rebecca S. Gruchalla, MD, of the University of Texas Southwestern Medical Center and Hugh A. Sampson, MD, of the Icahn School of Medicine at Mount Sinai in New York City. - Dr. Hugh Sampson, Professor, Pediatrics, Allergy and Immunology, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai Learn more: http://well.blogs.nytimes.com/2015/02/23/feeding-infants-peanut-products-could-prevent-allergies-study-suggests/?_r=0 Additional Coverage: Bloomberg: http://www.bloomberg.com/news/articles/2015-02-23/giving-peanuts-to-infants-as-young-as-4-months-can-deter-allergy Digital Journal: http://www.digitaljournal.com/life/health/new-treatment-may-cut-peanut-allergy-by-86-study-says/article/426829 CBC News: http://www.cbc.ca/news/health/peanut-allergies-can-be-reduced-in-high-risk-children-study-suggests-1.2967725 Examiner.com: http://www.examiner.com/article/skin-patch-may-help-protect-kids-with-peanut-allergies

Wall Street Journal – February 23 About-Face on Preventing Peanut Allergies – Sumathi Reddy A diet that includes peanuts in the first year of life may greatly reduce the chance of developing peanut allergies in children at risk for getting them, according to a highly anticipated new study. The findings appear to be the most definitive evidence yet to discount the medical community’s longtime recommendation that parents avoid giving peanut products to young children. Rebecca Gruchalla, MD, and Hugh Sampson, MD, director of the Jaffe Food Allergy Institute at The Mount Sinai Hospital in New York, wrote an editorial in the NEJM to accompany the new research, saying they believe the “landmark” study warrants new guidelines for when to introduce peanuts into children’s diets. - Dr. Hugh Sampson, Professor, Pediatrics, Allergy and Immunology, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai Learn more: http://www.wsj.com/articles/about-face-on-preventing-peanut-allergies-1424727014 Additional Coverage: Medscape: http://www.medscape.com/viewarticle/840212 Healthline: http://www.healthline.com/health-news/avoiding-peanuts-makes-kids-more-likely-to-become-allergic-022315#2 Live Science: http://www.livescience.com/49910-peanut-allergy-prevention-infants.html? utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+Livesciencecom+%28LiveScience.com+Science+Headline+Feed%29 Yahoo Health: https://www.yahoo.com/health/the-surprising-way-to-prevent-peanut-allergies-111875740492.html The Detroit News: http://www.detroitnews.com/story/news/2015/02/23/early-exposure-peanuts-helps-prevent-kids-allergies/23902577/

CBS News – February 22 New Data on Peanut Allergy Patch Shows Promise – Don Dahler About three million Americans are allergic to nuts, and most of them are allergic to peanuts. But relief may be on the way. A new study says the allergy patch Viaskin is showing promise. The study found that the patch allowed participants to have a higher tolerance for peanuts. Fifty percent of patients could eat up to four peanuts by the end of the year. "The big advantage with this patch is the safety and convenience," said Hugh Sampson, MD, with The Mount Sinai Hospital in New York. "With the patch we see local reactions but no systemic reactions." - Dr. Hugh Sampson, Professor, Pediatrics, Allergy and Immunology, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai Learn more: http://www.cbsnews.com/news/peanut-allergy-patch-showing-promise-in-trials/ Additional Coverage: WCBS TV: http://newyork.cbslocal.com/2015/02/23/study-exposing-kids-to-peanuts-early-may-prevent-allergies/ WCBS 880 News: No Web Link Available Science: http://news.sciencemag.org/biology/2015/02/eating-peanuts-prevents-allergy TheBlaze.com: http://www.theblaze.com/stories/2015/02/23/tiny-patch-offers-exciting-news-for-those-with-peanut-allergies/ Harvard Health: http://www.health.harvard.edu/blog/children-eat-peanuts-early-age-may-prevent-peanut-allergies-201502237751 Medical Xpress via Healthday: http://medicalxpress.com/news/2015-02-skin-patch-easing-peanut-allergy.html Allergic Living: http://allergicliving.com/2015/02/23/early-introduction-of-peanut-protects-against-allergy-leap-study-finds/

USA Today – February 23 Treatment Reduces Kids' Peanut Allergy Risk Up To 86% – Liz Szabo For the first time, researchers have shown that children who are regularly fed small amounts of peanuts from their infancy are actually less likely than others to develop peanut allergies. Doctors don't know whether the regimen will benefit babies at low risk for peanut allergies, says Scott Sicherer, MD, a professor of pediatrics and researcher at the Jaffe Food Allergy Institute at Mount Sinai in New York who wasn't involved in the new study. "We can presume that eating peanut earlier is still a good idea (for average-risk kids), but this study does not really address that," Sicherer says. - Dr. Scott Sicherer, Elliot and Roslyn Jaffe Professorship in Pediatric Allergy and Immunology, Icahn School of Medicine at Mount Sinai Learn more: http://www.usatoday.com/story/news/2015/02/23/peanut-allergy-cure/23883241/ Additional Coverage: Detroit Free Press: http://www.freep.com/story/life/wellness/2015/02/24/peanut-allergy-risk-exposure-study/23925781/

Chem.info – February 24 Study Says Prenatal Chemical Exposure Could Harm Infant Boys – Andy Szal A group of scientists from universities and medical research centers says it has produced one of the largest studies linking phthalate exposure to altered genitals in infant boys. The study found exposure to even low levels of diethylhexyl phthalate — a prominent plastic softener — during the first trimester of pregnancy could result in disrupted genital development in boys. “We saw these changes even though moms' exposure to DEHP has dropped 50 percent in the past 10 years,” said Shanna Swan, the report’s lead researcher and a professor at New York’s Icahn School of Medicine at Mount Sinai -Shanna Swan, PhD, Professor, Preventative Medicine, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://www.chem.info/news/2015/02/study-says-prenatal-chemical-exposure-could-harm-infant-boys Additional Coverage: Diario de Yucatan: http://yucatan.com.mx/salud/sustancias-plasticas-afectarian-los-recien-nacidos [Article is in Spanish]

Daily Life (Australia) – February 25 The Most Addictive Foods Revealed – Susie Burrell There are foods you cannot seem to stop eating no matter how hard you try, be they ice cream, chocolate or cheese. The concept of food addiction has been employed without a clear definition for some time, with associations made between certain types of food being consumed and the physiological and behavioral effects of drug use, such as increased impulsivity and emotional reactivity as well as specific patterns of brain activity. Now, recent research completed by the Icahn School of Medicine, in Mount Sinai, and published online by the Public Library of Science has furthered knowledge in this area. - Icahn School of Medicine at Mount Sinai Learn more: http://www.dailylife.com.au/health-and-fitness/dl-nutrition/the-most-addictive-foods-revealed-20150224-13n61h.html

Bloomberg – February 24 Scene Last Night: Huntsman, Lazard’s Yan Lan, Peter May, Cornell – Amanda L. Gordon The occasion was the gala for the Citizens Committee for New York City, which helps individuals improve their neighborhoods with grants ranging from $500 to $3,000. The event at Gotham Hall honored some people who’ve kept New Yorkers safe and healthy, such as former police commissioner Ray Kelly and Angela Diaz, director of the Mount Sinai Adolescent Health Center. Peter May, president of Trian Partners and chairman of Mount Sinai Health System, was on hand to introduce her. - Peter May, Chairman, the Board of Trustees, Mount Sinai Health System - Dr. Angela Diaz, Director, Mount Sinai Adolescent Health Center Learn more: http://www.bloomberg.com/news/articles/2015-02-24/scene-last-night-huntsman-lazard-s-yan-lan-peter-may-cornell

Medpage Today – February 24 Wise Buy? Drugs for Alzheimer's Dementia – Paul Raeburn On Sunday night when Julianne Moore collected an Oscar for her performance in the movie "Still Alice" when she portrayed a woman dealing with early-onset Alzheimer's disease, she noted that Alzheimer's is not only an incurable condition, but also "an incredibly isolating one." Four drugs are commonly prescribed for Alzheimer's dementia. Three of them are cholinesterase inhibitors, which "inhibit the enzyme that breaks down acetylcholine in the synapse," said Howard Fillit, MD, clinical professor of geriatrics and neuroscience at The Mount Sinai Hospital in New York City and chief science officer of the Alzheimer's Drug Discovery Foundation. "The benefits of cholinesterase inhibitors and Namenda are way overblown," said Samuel Gandy, MD, a neurologist who is also at The Mount Sinai Hospital in New York. - Dr. Samuel Gandy, Professor, Neurology, Psychiatry, Icahn School of Medicine at Mount Sinai - Dr. Howard Fillit, Clinical Professor, Geriatrics and Palliative Medicine, Neuroscience, Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.medpagetoday.com/Neurology/Dementia/50154

Scientific American – February 20 Science Goes to the Movies: A New TV Program – Steve Mirsky Heather Berlin, MD, assistant professor of psychiatry and of neuroscience at Icahn School of Medicine at Mount Sinai in New York City, is the co-host of the new CUNY TV program Science Goes to the Movies. Describing the show she says, “It’s sort of a movie review type of show but with a science lens.” The show will begin by focusing on contemporary films but then will evolve to include popular films from the past. - Dr. Heather Berlin, Assistant Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://www.scientificamerican.com/podcast/episode/science-goes-to-the-movies-a-new-tv-program/

Medpage Today – February 20 Cohen's Brain Bits: Varicella-Zoster, More than Just Shingles? – Joshua Cohen MD, MPH As a headache specialist, I am always concerned when patients over the age of 50 walk into my office with a new headache type. When they then report a temporal headache with tenderness to palpation and throw in visual changes, jaw claudication, or fever, they've bought themselves a direct trip to the stat lab for measurement of sed rate and C-reactive protein -- and if they report all of the above, I'm likely to walk them there myself. With its risk of blindness and stroke, giant cell arteritis (GCA) might be the scariest and most vexing condition a headache specialist sees. - Dr. Joshua Cohen, Assistant Professor, Neurology, Icahn School of Medicine at Mount Sinai Learn more: http://www.medpagetoday.com/Blogs/CohensBrainBits/50112?xid=nl_mpt_DHE_2015-02- 21&utm_content=&utm_medium=email&utm_campaign=DailyHeadlines&utm_source=ST&eun=g834835d0r&userid=834835&email=newsmedia%40mssm.edu&mu_id=6915236&utm_term=Daily

The Huffington Post – February 24 The IUD Is Getting More Popular In America. Here's Why – Jeffrey Young In 2011, the American College of Obstetricians and Gynecologists adopted new guidelines encouraging physicians to discuss IUDs with patients. The American Academy of Pediatrics followed last year by endorsing IUDs as a first-line contraceptive option for teenage girls. Physician organizations like these, and doctors themselves, are changing the way they think about long-acting reversible contraceptives because more studies have shown they are safe and effective for women at various ages, said Laura MacIsaac, MD, associate professor of obstetrics, gynecology and reproductive science at the Icahn School of Medicine at Mount Sinai in New York. - Dr. Laura MacIsaac, Associate Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Director, Family Planning, The Mount Sinai Health System Learn more: http://www.huffingtonpost.com/2015/02/24/iud-birth-control_n_6736218.html

WNYW – February 23 Bionic Eye Helps People See – Sharon Crowley In September, Philadelphia's Fran Fulton also underwent surgery to have a chip planted in her eye that sends a signal to the optic nerve controlled by special pair of glasses. The procedure, which costs upwards of $100,000, is not yet being done in New York but it will be soon. Richard Rosen, MD, is chief of retina service at the New York Eye and Ear Infirmary at The Mount Sinai Hospital. "Patients who were completely blind and really couldn't see anything can at least begin to appreciate patterns," he said. "It gives them some ability to navigate using light they lost a long time before." -Dr. Richard B. Rosen, Professor, Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, Surgeon Director, Retina Service Chief, and Director of Ophthalmology Research, New York Eye and Ear Infirmary Learn more: http://www.myfoxny.com/story/28182202/bionic-eye-helps-people-see

Los Angeles Confidential – February 23 How Julianne Moore Prepared for Her Oscar-Winning Role in 'Still Alice' – Luke Crisell Julianne Moore’s fastidious preparation for her role in ‘Still Alice’ started with a call to the director of the national Alzheimer’s Association, which set up Skype interviews for her with recently diagnosed early-onset patients across America. “I had a tremendous responsibility to get it right. I said, ‘I don’t want to do anything that’s not truthful.’” Moore even went to The Mount Sinai Hospital in New York to undergo the tests for the disease and attended support groups for women affected by it. -The Mount Sinai Hospital Learn more: http://la-confidential-magazine.com/personalities/articles/how-julianne-moore-prepared-to-play-an-alzheimers-patient-in-still-alice

Time Warner Cable News – February 23 Experts Say When it Comes to Fitness, Keep it Simple – Erin Billups Experts say kids need an hour of physical activity daily to stay healthy and reduce the risk of chronic diseases later in life. Finding the time to fit in that moderate to high physical activity may seem difficult, but it's easier than you think. "To get active, you got to find ways to make it a game," says Mount Sinai Beth Israel Center for Health and Healing Physical Therapist and Rehabilitation Coordinator Paul Hartmann. - Paul Hartmann, DPT, PT, Rehabilitation Coordinator, Mount Sinai Beth Israel Center for Health and Healing Learn more: http://www.ny1.com/nyc/bronx/fit-kids/2015/02/23/fit-kids-february--experts-say-when-it-comes-to-fitness--keep-it-simple-.html

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 23, 2015 Date: Monday, February 23, 2015 11:28:52 AM Attachments: ATT00001.txt

In the News February 23, 2015

Time – February 23 This ‘Peanut Patch’ Could Protect against Peanut Allergies – Justin Worland A small skin patch applied to patients with peanut allergies appears to safely and effectively protect against the sometimes life- threatening condition, researchers said Sunday “This is exciting news for families who suffer with peanut allergies because Viaskin represents a new treatment option for patients and physicians,” study author Hugh A. Sampson, MD, a doctor at Kravis Children’s Hospital at Mount Sinai, said in a statement. - Dr. Hugh Sampson, Professor, Pediatrics, Allergy and Immunology, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai, Director, the Jaffe Food Institute at Kravis Children’s Hospital at Mount Sinai Learn more: http://time.com/3718529/peanut-patch-allergy/ Additional Coverage: CBS News: http://www.cbsnews.com/news/peanut-allergy-patch-showing-promise-in-trials/ Today Health: http://www.today.com/health/peanut-patch-may-protect-against-life-threatening-allergy-2D80506626 The Seattle Times: http://www.seattletimes.com/seattle-news/health/peanut-patch-may-be-boon-for-allergy-sufferers-study-finds/ CTV: http://www.ctvnews.ca/health/peanut-patch-could-protect-allergy-sufferers-1.2248862 Headline and Global News: http://www.hngn.com/articles/71627/20150223/peanut-allergy-skin-patches-may-prevent-life- threatening-reaction.htm Health 24: http://www.health24.com/Medical/Allergy/News/New-skin-patch-might-ease-peanut-allergy-20150223 Utah People’s Post: http://www.utahpeoplespost.com/2015/02/peanut-allergy-treated-skin-patch-near-future/ RTI (China): http://news.rti.org.tw/news/detail/?recordId=173428 [Article is in Chinese] Apple Daily: http://www.appledaily.com.tw/realtimenews/article/new/20150223/563468/ [Article is in Chinese]

Healthday – February 22 Skin Patch Shows Promise in Easing Peanut Allergy – Steven Reinberg A wearable patch that safely and gradually exposes the body to small amounts of peanut allergen appears effective in easing the allergy, an early new study shows. The Viaskin peanut patch, worn for a year by peanut-allergic children and adults, appears to "educate cells to turn off the allergic reaction," said lead researcher Hugh Sampson, MD, director of the Jaffe Food Allergy Institute at Kravis Children's Hospital at Mount Sinai in New York City. - Dr. Hugh Sampson, Professor, Pediatrics, Allergy and Immunology, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai, Director, the Jaffe Food Institute at Kravis Children’s Hospital at Mount Sinai Learn more: http://consumer.healthday.com/respiratory-and-allergy-information-2/misc-allergy-news-17/coming-soon-a-peanut- allergy-patch-696736.html Additional Coverage: U.S. News & World Report: http://health.usnews.com/health-news/articles/2015/02/22/skin-patch-shows-promise-in-easing- peanut-allergy Philly.com: http://www.philly.com/philly/health/topics/HealthDay696736_20150222_Skin_Patch_Shows_Promise_in_Easing_Peanut_Allergy.html De Telegraaf (Netherlands): http://www.telegraaf.nl/gezondheid/23720485/___Pindapleister__biedt_hoop_bij_allergie__.html [Article is in Dutch]

The Huffington Post – February 23 You're Most Likely To Get Hooked On These Foods – Anna Almendrala While the concept of food addiction is controversial among researchers, there is growing evidence that highly-processed, fatty, sugary foods like pizza, chocolate, chips and cookies as uniquely problematic foods in people’s lives. In the latest study published on the subject, Nicole Avena, PhD, of the Icahn School of Medicine at Mount Sinai found that behaviors and attitudes surrounding some types of food closely followed addiction patterns. “Several studies really do suggest that highly-palatable, highly-processed foods can produce behaviors and changes in the brain that one would use to diagnose an addiction, like drugs and alcohol,” Avena told The Huffington Post. - Nicole Avena, PhD, Assistant Professor, Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai Learn more: http://www.huffingtonpost.com/2015/02/23/food-addiction_n_6709756.html Additional Coverage: WCBS TV: http://newyork.cbslocal.com/2015/02/18/researchers-say-knowledge-may-be-key-to-curbing-junk-food-binges/

The Nation – February 19 What the Anti-Vax Movement Doesn’t Tell You About Measles – Annemarie Sparrow, MD As doctors, there are a few things that we know are fundamental to our well-being. Most of these are public-health measures that enable us to live much longer and better lives, even to grow taller, than 200 years ago. These measures of mass salvation include water purification, toilets and sanitation, garbage collection and disposal, and vaccination to protect children from infectious diseases like smallpox, polio and measles. - Dr. Annemarie Sparrow, Assistant Professor, Preventative Medicine, Pediatrics, Icahn School of Medicine at Mount Sinai, Human Rights Director, the Arnhold Global Health Institute at Mount Sinai Learn more: http://www.thenation.com/article/198609/what-anti-vax-movement-doesnt-tell-you-about-measles#

Medpage Today – February 23 Early Immunotherapy Helps Kids Beat Peanut Allergy – Nancy Walsh Very young children who have shown reactivity to peanuts had a high rate of "sustained unresponsiveness" after stopping oral immunotherapy, researchers reported at the American Academy of Allergy, Asthma, and Immunology annual meeting. Strict avoidance has been the standard of care for peanut allergy, but children and parents alike have a substantial fear of low-level contamination. A speaker at the press conference, Hugh Sampson, MD, of the Icahn School of Medicine at Mount Sinai in New York City, said, "They don't care if the child can't eat a peanut butter sandwich. At least they're not going to die from contamination." - Dr. Hugh Sampson, Professor, Pediatrics, Allergy and Immunology, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai, Director, the Jaffe Food Institute at Kravis Children’s Hospital at Mount Sinai Learn more: http://www.medpagetoday.com/MeetingCoverage/AAAAI/50144

WNBC – February 21 Visiones: Asthma – Lynda Baquero Lynda Baquero is joined by Raja Flores, MD, to talk about innovations in asthma treatment for this week's Visiones. There are 19 million asthma sufferers in the United States and 40% of those are Latinos. “I think a lot of it has to do with socioeconomic reasons. Many Latinos are living in lower income housing where you have debris falling from the walls. They are living next to highways and things that can spew out a lot of irritants to the respiratory tract,” says Dr. Flores. - Dr. Raja Flores, Steven and Ann Ames Professorship in Thoracic Surgery, Icahn School of Medicine at Mount Sinai, System Chair, Thoracic Surgery, Mount Sinai Health System Learn more: http://www.nbcnewyork.com/video/#!/on-air/as-seen-on/Visiones--Asthma/293188071

Healio – February 2015 With The Growth Of Outpatient Orthopedic Spine Surgery, More Research Is Warranted As the potential and practicality of orthopedic spine surgery performed in the outpatient setting gains traction with both patients and surgeons, questions still remain about reimbursement, risk-to-benefit ratios, guidelines for follow-up care and decisions about which procedures should be done in this environment. “The question for spinal surgery is what are the appropriate kinds of procedures to be done in an ambulatory setting and which ones are best suited to be done in a hospital?” Andrew C. Hecht, MD, chief of spine surgery and associate professor in orthopedics and neurosurgery at The Mount Sinai Hospital in New York City, told Orthopedics Today. -Dr. Andrew Hecht, Associate Professor, Orthopaedics, Neurosurgery, Icahn School of Medicine at Mount Sinai, Director, the Spine Center at The Mount Sinai Hospital Learn more: http://www.healio.com/orthopedics/spine/news/print/orthopedics-today/%7Ba97055c2-d786-465f-b195- 2221d2ec6f93%7D/with-the-growth-of-outpatient-orthopedic-spine-surgery-more-research-is-warranted

Newsweek – February 22 The Search for the Perfect Sugar Substitute – Andrew P. Han There are reasons we like sugar so much. One of them is that our ancestors evolved in an environment where they had to forage for food. “The foods that are sweet tend to be safe,” says Nicole Avena, PhD, a researcher at Mount Sinai-St. Luke’s Hospital in New York who studies the effects of sugar on the brain. “Fruit that’s ripe and is good to eat tastes sweet. Fruit that’s rotten and could potentially kill you will not.” - Nicole Avena, PhD, Assistant Professor, Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai Learn more: http://www.newsweek.com/search-perfect-sugar-substitute-308480

Healthline News – February 20 Female Marine Breaks Silence on PTSD Struggle that Mirrors 'American Sniper' – David Heltz Rachel Yehuda, PhD, is director of the Traumatic Stress Studies Division at the Icahn School of Medicine at Mount Sinai in New York City as well as the director of the Mental Health Patient Care Center and PTSD Research Program at the James J. Peters Veterans Affairs Medical Center in the Bronx. She stressed there is no one-size-fits-all solution for treating people with PTSD and the other conditions that usually co-exist with it. “Where is the fire burning the fastest? This has to be done on a highly individualized basis,” Yehuda told Healthline. - Rachel Yehuda, PhD, Professor of Psychiatry and Neuroscience and Director of the Traumatic Stress Studies Division at the Icahn School of Medicine at Mount Sinai, Director, Mental Health Patient Care Center and PTSD Research Program at the James J. Peters Veterans Affairs Medical Center in the Bronx Learn more: http://www.healthline.com/health-news/female-american-sniper-breaks-silence-about-her-ptsd-022015

Modern Healthcare – February 21 The Rise of the Specialty Emergency Department – Beth Kutscher More than 10% of The Mount Sinai Hospital's 110,000 emergency department visits each year involve patients over age 65. Three years ago, the 1,048-bed New York City hospital—which is participating in a Medicare shared-savings accountable care organization—opened a dedicated geriatric ED designed to help coordinate care for these higher-risk patients. “There's sort of a silver tsunami approaching,” said Denise Nassisi, MD, director of geriatric emergency medicine at The Mount Sinai Hospital. “We planned it because we knew that geriatric patients really do require special handling.” - Dr. Denise Nassisi, Associate Professor, Emergency Medicine, Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai, Director, Geriatric Emergency Medicine, The Mount Sinai Hospital Learn more: http://www.modernhealthcare.com/article/20150221/MAGAZINE/302219980/the-rise-of-the-specialty-emergency- department

The Huffington Post – February 20 Is It Okay to Give My Child Over-the-Counter Cough Medicine? – Meredith Grossman, MD Even though product labels on most packages of over-the-counter (OTC) cough medicines state, "Do not use in children under 4 years of age," I generally recommend that parents not give cough medicine to children of any age. As a pediatrician, my main concern is the potential for rare but serious neurologic side effects involving the central nervous system, including confusion, irritability, and nervousness. The good news is that there are several safe, supportive measures parents can try to help alleviate their child's cough. - Dr. Meredith Grossman, Assistant Professor, Pediatrics, General Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: http://www.huffingtonpost.com/mount-sinai-health-system/is-it-okay-to-give-my-child-over-the-counter-cough- medicine_b_6714362.html

Yahoo Health – February 20 Do Americans Shower More Or Less Than The Rest Of The World? – Grace Gold Americans have long had a reputation for a “squeaky clean” devotion to hygiene that fuels a $3.1 billion body soap industry, yet recent studies show that Americans are actually quite average when compared to how often people shower worldwide. “In the U.S. people commonly shower once or even more per day – this can actually be harmful to skin, as hot water strips essential oils and can lead to irritation,” Joshua Zeichner, MD, director of cosmetic and clinical research at Mount Sinai Hospital’s Department of Dermatology, told Yahoo Health. - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: https://www.yahoo.com/health/do-americans-shower-more-or-less-than-the-rest-of-111508762932.html

The New York Daily News – February 22 Rehab Work Can Help Your Heart Get Healthy, Stay Healthy – Katie Charles Rehab is something most of us associate with recovering from knee surgery or a hip replacement, but the heart also can benefit from therapies. “Cardiac rehabilitation, or rehab, is a comprehensive multidisciplinary program that works to improve your heart health,” says the associate director of cardiac rehabilitation at The Mount Sinai Hospital, Rajesh Vedanthan, MD. “Its goal is to provide a program of exercise, education and behavior modification to help get patients get back to emotional, physical and socio- behavioral health.” -Dr. Rajesh Vendanthan, Assistant Professor, Medicine, Cardiology, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai Learn more: http://www.nydailynews.com/life-style/rehab-work-heart-article-1.2118623 Additional Coverage: Health AIM: http://www.healthaim.com/cardiac-rehab-get-heart-healthy-5-ways-healthy-heart/13863

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 20, 2015 Date: Friday, February 20, 2015 12:15:47 PM Attachments: ATT00001.txt

In the News February 20, 2015

Healthday – February 19 Plastics Chemical Tied to Changes in Boys' Reproductive Development – Steven Reinberg Boys exposed to the chemical diethylhexyl phthalate (DEHP) may be born with a significantly shorter anogenital distance than those not exposed to these chemicals, a new study suggests. Anogenital distance is the distance between the anus and the genitals. A shorter anogenital distance has been linked to infertility and low sperm count, the researchers explained. "We saw these changes even though moms' exposure to DEHP has dropped 50 percent in the past 10 years," said lead researcher Shanna Swan, PhD, a professor of preventive medicine and obstetrics, gynecology and reproductive medicine at the Icahn School of Medicine at Mount Sinai in New York City. -Shanna Swan, PhD, Professor, Preventative Medicine, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/disabilities-information-11/misc-birth-defect-news- 63/exposure-to-plastic-chemicals-tied-to-changes-boys-reproductive-development-696623.html Additional Coverage: CBS News: http://www.cbsnews.com/news/phthalates-dehp-chemical-in-plastics-boys-future-fertility/ Newsmax: http://www.newsmaxhealth.com/Health-News/plastics-chemical-genital- phthalates/2015/02/19/id/625793/ Monthly Prescribing Reference: http://www.empr.com/phthalate-exposure-in-first-trimester-may-affect- male-fertility-in-offspring/article/399231/

Psych Central – February 20 Growth Hormone Improves Social Impairments From Autism-Linked Disorder – Janice Wood New research has found that a growth hormone can significantly improve the social impairment associated with autism spectrum disorder (ASD) in patients with a related genetic syndrome. The pilot study, conducted at the Icahn School of Medicine at Mount Sinai, focused on the use of insulin-like growth factor-1 (IGF-1) to treat Phelan-McDermid syndrome (PMS), a disorder caused by a deletion or mutation of the SHANK3 gene on chromosome 22. “Ours is the first controlled trial of any treatment for Phelan-McDermid syndrome,” said Alexander Kolevzon, MD, clinical director of the Seaver Autism Center at the Icahn School of Medicine at Mount Sinai. - Dr. Alexander Kolevzon, Associate Professor, Psychiatry, Pediatrics, Clinical Director, the Seaver Autism Center at the Icahn School of Medicine at Mount Sinai Learn more: http://psychcentral.com/news/2015/02/20/growth-hormone-improves-social-impairments- from-autism-linked-disorder/81467.html Additional Coverage: Business Standard: http://www.business-standard.com/article/news-ians/growth-hormone-helps- improve-autism-linked-disorder-115022000639_1.html News-Medical: http://www.news-medical.net/news/20150220/Study-Growth-hormone-can-improve- social-impairment-in-patients-with-Phelan-McDermid-syndrome.aspx Medical Xpress: http://medicalxpress.com/news/2015-02-growth-hormone-social-impairments-autism- linked.html Zee News: http://zeenews.india.com/news/health/health-news/growth-hormone-helps-improve-autism- linked-disorder_1549906.html

The New York Daily News – February 19 Processed Foods Are Addictive: Study – Meredith Engel Researchers have long suspected that some processed foods are just as addictive as hard drugs — but a new study shows that people jones for sugar-, fat- and salt-laden foods in the same way that druggies yearn for their daily fix. The University of Michigan and Mount Sinai Hospital study piggybacks on a 2013 finding that Oreos are just as addictive as cocaine — but that study was on mice. This one was on humans, who were given addiction questionnaires — but with food varieties swapped for drug types. "There is a biological basis," said Nicole Avena, assistant professor of pharmacology and systems therapeutics at Mount Sinai’s Icahn School of Medicine. "It can't be all self-blame on the individual." - Nicole Avena, PhD, Assistant Professor, Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai Learn more: http://www.nydailynews.com/life-style/health/highly-processed-foods-addictive-study- article-1.2121735 Additional Coverage: WCBS: http://newyork.cbslocal.com/2015/02/18/researchers-say-knowledge-may-be-key-to-curbing- junk-food-binges/ WNYW: No Web Link Available

Focus (Poland) – February 20 Does The TV Cause Aggression? Scientists from the Icahn School of Medicine at Mount Sinai in New York conducted a study which shows that the films showing violence can cause aggression only in those viewers who have a tendency to it. More than 50 men were divided into two groups. In one there were those who in the past acted aggressively or otherwise had contact with violence, the other had people without such experience. While watching violent films participants of the "aggressive" reacted differently than "non-aggressive." - Icahn School of Medicine at Mount Sinai Learn more: http://www.focus.pl/sekrety-nauki/czy-telewizja-wywoluje-agresje-12227 [Article is in Polish]

Crain’s Health Pulse – February 20 At a Glance Neuropsychiatric researcher Alison Goate, PhD, joined the Mount Sinai Health System in January as the founding director of the Ronald M. Loeb Center for Alzheimer’s Disease. The center was established using a recent $15 million gift from Daniel Loeb, chief executive and founder of Third Point, and his wife, Margaret Munzer Loeb, in memory of Daniel’s father. Dr. Goate had been a researcher and professor of genetics in psychiatry at the Washington University School of Medicine. - Alison Goate, PhD, Senior Faculty, Neuroscience, Neurology, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Founding Director, The Ronald M. Loeb Center for Alzheimer’s Disease at Mount Sinai Learn more: http://www.crainsnewyork.com/article/20150220/PULSE/150219830/oversight-panel- swoons-over-doctor-led-network

Healthday – February 19 Mammogram Rates May Fall When Women Learn of 'Overdiagnosis' Risk – Robert Preidt Educating women about the possibility of "overdiagnosis" from mammography screening may make some of them less likely to get the test, a new study says. Dr. Alison Estabrook is chief of breast surgery at the Comprehensive Breast Center at Mount Sinai Roosevelt Hospital in New York City. She agreed that -- as happens with all cancer screening tools -- mammograms can lead to overdiagnosis. She said the study brings up a number of important questions: "Can we find a group of women that does not need to be screened every year? Can we educate surgeons and other breast oncologists not to overtreat early cancers?" - Dr. Alison Estabrook, Chief, Comprehensive Breast Surgery, Mount Sinai St. Luke’s and Mount Sinai Roosevelt Learn more: http://consumer.healthday.com/cancer-information-5/breast-cancer-news-94/mammogram- rates-may-fall-when-women-learn-of-risk-for-over-diagnosis-696602.html

Yahoo News via Agence France-Presse – February 19 Cholesterol No Longer a Concern: US Experts – Kerry Sheridan A warning against eating foods high in cholesterol is no longer included in the US government's draft dietary guidelines for Americans, representing a major shift in policy, officials said Thursday. The recommended changes show "good progress in the arena of nutrition science," said Rebecca Solomon, director of clinical nutrition at Mount Sinai Beth Israel hospital in New York. "We have known for many years that cholesterol levels are impacted primarily by genetics and high saturated fat intake and not by intake of dietary cholesterol. I am happy to see this evolved position." - Rebecca Solomon, MS, RD, CDN, Director, Clinical Nutrition, Mount Sinai Beth Israel Learn more: http://news.yahoo.com/cholesterol-no-longer-concern-us-experts- 205548731.html;_ylt=AwrBEiF8VOZUow0AKrfQtDMD Additional Coverage: AFP BB: http://www.afpbb.com/articles/-/3040196 [Article is in Japanese] The Star Online: http://www.thestar.com.my/News/World/2015/02/20/Cholesterol-no-longer-a-concern- US-experts/ Asia One: http://yourhealth.asiaone.com/content/cholesterol-no-longer-concern-us-experts Luxemburger Wort (Luxembourg): http://www.wort.lu/en/lifestyle/more-butter-anyone-cholesterol-is- no-longer-a-concern-say-us-experts-54e6d3f00c88b46a8ce53ddf Malay Online (Malaysia): http://www.themalaymailonline.com/features/article/good-news-us-experts- claims-cholesterol-no-longer-a-concern Maine News Online: http://mainenewsonline.com/content/15022966-significant-changes-made-new- dietary-guidelines

Healthday – February 19 More Americans Dying From Hypothermia, CDC Says – Dennis Thompson More people are dying from hypothermia in the United States, a new government report shows, raising fresh worries for a nation that has been pounded by a steady succession of winter storms this year. "There's a recurrent problem every year, and it always happens during these cold snaps where there are multiple days in a row in which the temperature drops below freezing," said Vaishali Patel, MD, an assistant professor of emergency medicine at the Icahn School of Medicine at Mount Sinai, in New York City. - Dr. Vaishali Patel, Assistant Professor, Emergency Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/environmental-health-information-12/environment-health- news-233/hypothermia-696679.html Additional Coverage: Doctors Lounge: http://www.doctorslounge.com/index.php/news/hd/53195

CNN Indonesia – February 20 Why Acne Keeps Appearing in the Same Place – Windratie Can you predict the location of your acne as accurately as the date of your next menstruation? Some people experience repeated acne breakouts in the same location. Fortunately, there are steps that can be taken to end stubborn and frustrating acne, says Joshua Zeichner, MD, director of cosmetic and clinical research dermatology at The Mount Sinai Hospital, New York City. - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.cnnindonesia.com/gaya-hidup/20150220064522-255-33456/penyebab-jerawat- terus-muncul-di-tempat-yang-sama/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 19, 2015 Date: Thursday, February 19, 2015 11:54:03 AM Attachments: ATT00001.txt

In the News February 19, 2015

Fox News – February 18 Highly Processed Foods Tied to Addictive Eating, May Pave Way for Obesity Treatment – Lindsay Carlton A new study from the University of Michigan and the Icahn School of Medicine at Mount Sinai confirms what’s long been suspected— highly processed foods like chocolate, pizza and French fries are the most addictive. Researchers believe their findings may pave the way for more effective treatments for obesity. “This could help change the way we approach obesity treatment. It may not be a simple matter of 'cutting back' on certain foods, but rather, adopting methods used to curtail smoking, drinking and drug use,” Nicole Avena, an assistant professor of pharmacology and systems therapeutics at Icahn said in the news release. - Nicole Avena, PhD, Assistant Professor, Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai Learn more: http://www.foxnews.com/health/2015/02/18/highly-processed-foods-tied-to-addictive-eating- may-pave-way-for-obesity/ Additional Coverage: Medical Xpress: http://medicalxpress.com/news/2015-02-highly-foods-linked-addictive.html Philly.com: http://www.philly.com/philly/health/topics/HealthDay696504_20150218_Study_Compares_Drugs_for_Diabetes- Linked_Eye_Disease.html Health Canal: http://www.healthcanal.com/disorders-conditions/eating-disorders/60360-highly-processed- foods-linked-to-addictive-eating.html University of Michigan News: http://ns.umich.edu/new/releases/22693-highly-processed-foods-linked-to- addictive-eating

WCBS TV – February 19 Researchers Say Knowledge May Be Key To Curbing Junk Food Binges Pizza, chocolate, and chips can be as addicting as drugs — that’s the new revelation from a study released on Wednesday. “Foods can have addictive like qualities,” said Nicole Avena, PhD, a research professor at The Mount Sinai Hospital. Avena spent the past year testing hundreds of people. She isolated 35 foods ranging from pizza to vegetables to soda. Each participant then rated the food based on how problematic it was, meaning if they lost control over how much they ate. - Nicole Avena, PhD, Assistant Professor, Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai Learn more: http://newyork.cbslocal.com/2015/02/18/researchers-say-knowledge-may-be-key-to-curbing- junk-food-binges/

Healthday – February 18 Study Compares Drugs for Diabetes-Linked Eye Disease – Robert Preidt A vision-robbing condition called diabetic macular edema can strike people with diabetes. Now, a new study compared three leading drugs for the condition -- Avastin, Eylea and Lucentis -- and found that Eylea came out on top, at least for patients with "moderate" vision loss. Ronald Gentile, MD, is professor of ophthalmology at the New York Ear and Eye Infirmary of Mount Sinai, in New York City, and was an investigator on the trial. He said that "the importance of this study can't be overstated. These one-year results highlight the fact that all the drugs studied -- Eylea, Avastin and Lucentis -- are potentially effective [treatment] options." - Dr. Ronald Gentile, Professor, Ophthalmology, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/eye-care-information-13/eye-and-vision-problem-news- 295/study-tests-drugs-for-diabetes-linked-eye-disease-696504.html

Live Science – February 19 Chemical in Plastics May Alter Boys' Genitals before Birth – Lindsey Konkel Baby boys who are exposed in the womb to a chemical used in soft plastics may show small signs of altered genital development, according to new research published today. The study, which included more than 700 infants in four U.S. cities, is the largest of its kind to date. The changes seen in the babies in the study were small, said lead author Shanna Swan, MD, a reproductive health scientist at The Mount Sinai Hospital in New York. "There was nothing clinically abnormal or noticeably different about these boys," Swan told Live Science. -Dr. Shanna Swan, Professor, Preventative Medicine, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://www.livescience.com/49870-phthalates-chemical-plastics-boys-genital-development.html Additional Coverage: Yahoo News UK via Live Science: https://uk.news.yahoo.com/chemical-plastics-may-alter-boys-genitals- birth-145810735.html#9QF5fN5

Healthline – February 18 Seasonal Flu Vaccine Protects Against H7N9 Bird Flu – Brian Krans Researchers at the University of Chicago and the Icahn School of Medicine at Mount Sinai in New York came across an unexpected result when they were studying flu shot reactions. In their study, published Tuesday in The Journal of Clinical Investigation, the research team reports the flu vaccine activates three of the 83 antibodies that attack H3 viruses, including H7N9. - Icahn School of Medicine at Mount Sinai Learn more: http://www.healthline.com/health-news/seasonal-flu-vaccine-protects-against-h7n9-bird-flu- 021815 Additional Coverage: The Huffington Post Canada: http://www.huffingtonpost.ca/2015/02/18/flu-shot-h7n9_n_6705380.html The Borneo Post: http://www.theborneopost.com/2015/02/18/flu-shot-protects-against-new-h7n9-strain- study/

The Guardian Nigeria – February 19 Why Healthy Diet, Exercise Are Not Enough to Treat Obesity People who are obese are often told to eat healthier and exercise more in order to lose weight. But in an article recently published in The Lancet Diabetes & Endocrinology, obesity experts claim the condition is a chronic disease that can be caused by biological factors, meaning many cases may not be cured with a healthy diet and physical activity alone. Lead author Christopher Ochner, PhD, said, “Although lifestyle modifications may result in lasting weight loss in individuals who are overweight, in those with chronic obesity, body weight seems to become biologically ‘stamped in’ and defended.” -Christopher Ochner, PhD, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.ngrguardiannews.com/features/natural-health/198647-why-healthy-diet-exercise- are-not-enough-to-treat-obesity Additional Coverage: South China Morning Post: http://www.nanzao.com/tc/lifestyle/48203/jian-zhong-mian-fan-dan-jie-shi-jia- yun-dong-huan-bu-gou [Article is in Chinese]

The Harvard Crimson – February 19 Study Finds Strong Genetic Component to Obesity – Melanie Fu and Jiwon Joung A new finding by the Genetic Investigation of Anthropometric Traits, or GIANT, consortium has identified 97 gene regions associated with obesity, tripling the number of such genes previously known. The study, which stands as the largest genome study conducted to date, was led by Harvard Medical School professor Joel N. Hirschhorn. This medical advancement did not come without time and effort. Ruth J.F. Loos, professor for preventative medicine at The Mount Sinai Hospital in New York, said the study has been in the works for many years. “It took us about four years to combine even more data and that is what was published recently,” she said. According to Loos, the paper is the most recent in a series of publications and represents the work of 125 studies, which used about 340,000 individuals as subjects. -Ruth Loos, PhD, Director of the Genetics of Obesity and Related Metabolic Traits Program at the Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.thecrimson.com/article/2015/2/19/gene-study-obesity-genetics/

ABC News – February 18 Undetected Ectopic Pregnancy Leaves Woman in Coma – Sydney Lupkin The family of a pregnant woman who has been in a coma since Sunday is blaming the hospital that they say failed to realize she was experiencing a ruptured ectopic pregnancy and bleeding internally. Ectopic pregnancies are relatively common and occur in about 1 percent of all pregnancies, said Dr. Marjorie Greenfield, chief of general obstetrics and gynecology at UH Case Medical Center in Cleveland, Ohio. As a result, hospitals have experience spotting and treating them, she said. But sometimes a doctor can't spot an ectopic pregnancy until he or she operates, said Keith Eddleman, MD, director of obstetrics at The Mount Sinai Hospital in Manhattan. “If you have a patient in the first trimester with abdominal pain and bleeding and you can't see the pregnancy inside the uterus -- and you have a positive pregnancy test -- you have to assume it's ectopic until proven otherwise because it is life-threatening," Eddleman said. - Dr. Keith Eddleman, Professor, Obstetrics, Gynecology and Reproductive Science, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Director, Obstetrics, the Mount Sinai Hospital Learn more: http://abcnews.go.com/Health/undetected-ectopic-pregnancy-leaves-woman-coma/story? id=29058304 Additional Coverage: Inquisitr: http://www.inquisitr.com/1854710/ectopic-pregnancy-woman-in-coma/ EverythingLubbock.com: http://www.everythinglubbock.com/story/d/story/undetected-ectopic-pregnancy- leaves-woman-in-coma/56994/CNCrJ1MuHk6lhSj06T429w

El Diario New York – February 12 Veterans “Abuse Drugs, Alcohol and Think About Suicide” – Pedro F. Frisneda It is not known whether Stress Disorder Post-traumatic stress disorder (PTSD) affects Hispanic veterans differently than non-Hispanic whites or black veterans. What is known is that this disease, characterized by great anxiety developed after a traumatic event, afflicts military differently than other patients who have been victims of a violation, accident or natural disaster. Rachel Yehuda, PhD, director of the Division of Traumatic Stress Studies in the Icahn School of Medicine at Mount Sinai, says that PTSD affects about 30% of veterans who have been in active combat. She says, "Just the fact of being displaced, being away and in another environment, can really affect them. The stress of being deployed in a combat zone may even disturb them before they have been exposed to an incident that threatened their lives." - Rachel Yehuda, PhD, Professor of Psychiatry and Neuroscience and Director of the Traumatic Stress Studies Division at the Icahn School of Medicine at Mount Sinai, Director, Mental Health Patient Care Center and PTSD Research Program at the James J. Peters Veterans Affairs Medical Center in the Bronx Learn more: http://www.eldiariony.com/noticias-salud-excombatientes-padecimientos-drogas-suicidio [Article is in Spanish]

Dermatology Times – February 19 Teledermatology Enables Efficient Patient Triage – Louise Gagnon Some have seen the void in dermatological care in the United States and have taken the opportunity to develop private services to match up patients with board-certified dermatologists licensed in a patient's geographic area to provide dermatological care. Dermatologist-On-Call was launched in response to consumer preparedness for teledermatology and technology advances that ensure privacy and supply high- resolution images. Cameron Rokhsar, MD, FAAD, a board-certified dermatologist and assistant clinical professor of dermatology at The Mount Sinai Hospital in New, New York, said the conventional thinking is that live interaction trumps a video conferencing consultation, but store-and-forward technology is a much more convenient teledermatology format for busy teledermatologists. "Most dermatologists probably feel that there is nothing that can truly substitute a face-to-face consultation," says Dr. Rokhsar. "You can show someone a picture, but that picture is truly not the same thing as seeing the patient live." - Dr. Cameron Rokhsar, Assistant Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://dermatologytimes.modernmedicine.com/dermatology-times/news/teledermatology- enables-efficient-patient-triage

Drug Discovery & Development – February 18 Is Strenuous Running Really as Bad for Health as Lounging? – Cynthia Fox Running hard may be as bad for your longevity as being a couch potato, says a recent study—one that should be taken with a grain of salt (hold the butter), say some critics. The study, in a recent Journal of the American College of Cardiology, examined 5,048 healthy people enrolled in the Copenhagen City Heart Study. For 12 years, 1,098 healthy joggers and 413 healthy, but sedentary non-joggers were followed. In an accompanying commentary, The Mount Sinai Hospital cardiologist Rajesh Vedanthan and colleagues called the results “intriguing.” But they noted the study had many limitations. Among them: only sedentary non-joggers were included. Active non-joggers were not. -Dr. Rajesh Vendanthan, Assistant Professor, Medicine, Cardiology, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai Learn more: http://www.dddmag.com/news/2015/02/strenuous-running-really-bad-health-lounging

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 18, 2015 Date: Wednesday, February 18, 2015 11:27:53 AM Attachments: ATT00001.txt

In the News February 18, 2015

Yahoo via Agence France-Presse – February 18 Flu Shot Protects Against New Strain H7N9: Study The flu vaccine may not have protected most people against influenza circulating widely this season, but a study Tuesday showed it was effective against the new H7N9 strain that emerged in China in 2013. Antibodies that protect against H7N9 avian flu make up a small portion of people's immune response to the annual flu shot, "but appear to broadly neutralize H7 viruses and represent promising new targets for therapeutic development against a wide range of influenza strains," according to the research by the University of Chicago and Icahn School of Medicine at Mount Sinai. - Icahn School of Medicine at Mount Sinai Learn more: http://news.yahoo.com/flu-shot-protects-against-h7n9-strain-study-000957578.html Additional Coverage: Yahoo News UK: https://uk.news.yahoo.com/flu-shot-protects-against-h7n9-strain-study- 000957838.html#0rJeiID Medical News Today: http://www.medicalnewstoday.com/articles/289549.php Medical Xpress: http://medicalxpress.com/news/2015-02-seasonal-flu-vaccine-antibodies-h7n9.html Genetic Engineering & Biotechnology News: http://www.genengnews.com/gen-news- highlights/seasonal-flu-vaccine-may-provide-protection-against-deadly-avian-strain/81250938/ Infection Control Today: http://www.infectioncontroltoday.com/news/2015/02/seasonal-flu-vaccine- induces-antibodies-that-protect-against-h7n9-avian-flu.aspx Le Figaro (France): http://www.lefigaro.fr/flash-actu/2015/02/17/97001-20150217FILWWW00465-le- vaccin-efficace-contre-la-prochaine-grippe.php [Article is in French]

Alzheimer’s News Today – February 18 Preparing Foods at High Temperatures Might Increase the Risk of Alzheimer’s Disease – Daniela Semedo, PhD A recent study found that preparing foods at high temperatures might increase the risk of Alzheimer’s disease. Results from this study entitled “Observational and ecological studies of dietary advanced glycation end products in national diets and Alzheimer’s disease incidence and prevalence” also revealed that meat has the highest AGEs (advanced glycation end products) levels, with vegetable oils, cheese and fish also having high levels. Furthermore, foods like cereals, eggs, fruits, legumes, milk, nuts, etc., have a lower contribution of AGEs, since they are cooked at lower heats or because they are eaten in small portions. According to Jaime Uribarri, MD, and Weijing Cai of The Icahn School of Medicine at Mount Sinai in a recent press release, “This epidemiological study supports our previous findings in animals and humans of an important role for dietary AGEs in Alzheimer’s disease.” -Dr. Jaime Uribarri, Professor, Medicine, Nephrology, Icahn School of Medicine at Mount Sinai -Weijing Cai, PhD, Senior Scientist, Geriatrics and Palliative Care, Icahn School of Medicine at Mount Sinai Learn more: http://alzheimersnewstoday.com/2015/02/17/preparing-foods-at-high-temperatures-might- increase-the-risk-of-alzheimers-disease/ Additional Coverage: Nordjyske: http://www.nordjyske.dk/nyheder/derfor-skal-du-ikke-stege-koedet-haardt/6de1586d-83a4- 421a-937b-6c0351b1b9eb/112/1513 [Article is in Danish]

The Legal Examiner – February 17 A Flu Vaccine to Combat All Strains – David Carney This year’s flu vaccine has only been 23 percent effective, the Associated Press has reported. The H3N2 virus that mutated after the production of the vaccine caused a less effective vaccine and a particularly bad flu season. The flu vaccine does not protect against all strains of the flu—not yet. Scientists at The Mount Sinai Health System are in the process of developing a universal flu vaccine, according to Good Morning America. The universal vaccine would provide protection against all flu viruses for up to two decades. - The Mount Sinai Health System Learn more: http://phoenix.legalexaminer.com/fda-prescription-drugs/a-flu-vaccine-to-combat-all- strains/

Healthcare Dive – February 17 HIEs Used to Study Homeless Patients' Healthcare Use – Anne Zieger Researchers at The Mount Sinai Hospital in New York City hope to help reduce extraneous utilization of services by the homeless by using the HIE records to identify patients who may be homeless, as evidenced by their utilization patterns. There are several charities and public/private partnerships trying to examine this problem, but they tend to be pilot projects with small budgets. Seeing Mount Sinai in the game, using some innovative research methods, is a good sign that the industry will find new ways to manage caring for the needy. - The Mount Sinai Hospital Learn more: http://www.healthcaredive.com/news/hies-used-to-study-homeless-patients-healthcare- use/364813/

Quartz – February 18 Toxic Exposure Could Be Causing a Pandemic of Brain Disorders in Kids – Elizabeth Grossman According to the US Centers for Disease Control and Prevention, about 1.8 million more children in the US were diagnosed with developmental disabilities between 2006 and 2008 than a decade earlier. During this time, the prevalence of autism climbed nearly 300%, while that of attention deficit hyperactivity disorder increased 33%. CDC figures also show that 10 to 15% of all babies born in the US have some type of neurobehavorial development disorder. Such impairments affect millions of children worldwide. Philippe Grandjean of the University of Southern Denmark and Harvard T.H. Chan School of Public Health and Philip Landrigan of the Icahn School of Medicine at Mount Sinai in New York—both physicians and preeminent researchers in this field—describe the situation as a “pandemic.” - Dr. Philip Landrigan, Professor and System Chair, Preventative Medicine, Professor, Pediatrics, Dean for Global Health, Icahn School of Medicine at Mount Sinai Learn more: http://qz.com/345627/toxic-exposure-is-causing-a-pandemic-of-brain-disorders-in-kids/

Allergic Living – February 17 Inside the Search for Chinese Herbal Food Allergy Treatments – Claire Gagne Whenever there is talk of a cure for food allergies, hopes soar. One area of research that has had consistently promising studies in the last few years has been the Food Allergy Herbal Formula, currently called B-FAHF-2, which is being developed by Xiu-Min Li, MD, at the Icahn School of Medicine at Mount Sinai in New York. What we often don’t hear about, however, are the people who toil in the labs, making this research possible. One such person is Ying Song, MD, a professor of pediatrics at The Mount Sinai Hospital, an expert in mice and allergy research and a key player on the herbal formula research team. - Dr. Xiu-Min Li, Professor, Pediatrics, Allergy and Immunology, Icahn School of Medicine at Mount Sinai -Dr. Ying Song, Instructor, Pediatrics, Allergy and Immunology, Icahn School of Medicine at Mount Sinai Learn more: http://allergicliving.com/2015/02/18/inside-search-for-chinese-herbal-allergy-treatment/

Tech Times – February 18 Bodybuilders Are Slurping Breast Milk To Build Muscle But Is It A Good Idea? – Judy Mottl Bodybuilders are posting the "got milk?" question to lactating women looking to sell breast. Apparently some bodybuilders are striving to get some breast milk into their diet and vitamin regimen with the belief that breast milk can give them an edge in building bulk and muscle. The problem, researchers say, is that there is no scientific evidence that breast milk provides adults with any of those benefits. "There is nothing specific in breast milk that will cause adults to gain muscle mass," said Jacques Moritz, MD, director of the division of gynecology at New York's Mount Sinai Roosevelt. - Dr. Jacques Moritz, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Director, Gynecology, Mount Sinai St. Luke’s and Mount Sinai Roosevelt Learn more: http://www.techtimes.com/articles/33543/20150218/bodybuilders-are-slurping-breast-milk- to-build-muscle-but-is-it-a-good-idea.htm Additional Coverage: The Daily Mail: http://www.dailymail.co.uk/news/article-2958478/Bodybuilders-desperate-bulk-turning- BREAST-milk-online-risking-health-staph-infections.html KVUE: http://www.kvue.com/story/news/health/2015/02/18/why-bodybuilders-are-pounding-down- breast-milk/23605325/ RTV6: http://www.theindychannel.com/news/local-news/watch-bodybuilders-try-muscle-up-by- drinking-breast-milk Youth Health Magazine: http://www.youthhealthmag.com/articles/9997/20150217/bodybuilders-protein- breast-milk-benefits-of-breast-milk-can-adults-drink-breast-milk.htm KVNU: http://www.610kvnu.com/health/8c9f105ecb0203dbd87629aa91f4b8c3 Medisite: http://www.medisite.fr/a-la-une-ces-hommes-qui-boivent-du-lait-maternel-pour-entretenir- leurs-muscles.801257.2035.html [Article is in French]

USA Today via OZY – February 17 The Best-Kept Secret on Wall Street Might Be Therapy – Farah Halime It’s been six years since the global financial crisis sent heart rates soaring, but that was just the beginning for some traders, bankers and financial analysts, whose stress levels are still high. More is being demanded of them due to ongoing job cuts on Wall Street, and concerns are growing over the plummeting price of oil, deflation and increasingly volatile stock markets. “The money situation got scary,” says Anne Ziff, clinical assistant professor at the Icahn School of Medicine at Mount Sinai and a New York-based therapist. She saw divorce rates hit between 30 and 40 percent among her clients and is now creating a group therapy program for those in the financial industry. - Anne Ziff, PhD, Assistant Clinical Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.usatoday.com/story/money/business/2015/02/18/ozy-wall-street- therapy/23571779/

WCBS TV – February 17 Obesity Screenings for Children – Max Gomez Heart disease is still the leading cause of death in the United States. For many people, the problems begin when they are children. WCBS’s Max Gomez says that is why some doctors are making recommendations that may surprise you. Experts are worried that childhood obesity has doubled in the past 30 years, and most of those kids already have risk factors for heart disease. “Obesity in childhood leads to obesity in adulthood,” says Laura Popper, MD, “The earlier we know that children have high cholesterol and hypertension or other problems from obesity, we can get in and start to change their life.” -Dr. Laura Popper, Assistant Clinical Professor, Pediatrics, General Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: http://www.nydailynews.com/life-style/heart-month-article-1.2108744

The Stir – February 16 7 Worst Reasons to Ask for a C-Section – Judy Dutton About 2.5 percent of cesareans are elective, meaning the mom chooses it over vaginal delivery. Why? Well, moms may cite a variety of reasons, and may be coaxed by doctors as well. Still, these "reasons" don't always hold up to the reality, so make sure you aren't buying into the hype of one of these "bad" reasons to ask for an elective C-section below. Bad reason: You think a C-section is less painful than vaginal birth. The reality: "A C-section is major abdominal surgery and definitely more painful, with a longer recovery, than a vaginal delivery," says Fahimeh Sasan, MD, an OB/GYN at The Mount Sinai Hospital. - Dr. Fahimeh Sasan, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://thestir.cafemom.com/pregnancy/181805/why_get_elective_csection_cesarean

Anesthesiology News – February 2015 Perioperative Surgical Home Promotes Perioperativists – Brian Dunleavy What’s in a name? Everything to proponents of the American Society of Anesthesiologists’ (ASA) concept of the Perioperative Surgical Home (PSH), which sees the anesthesiologists’ role in the surgical suite morphing into that of a “perioperativist.” Alan E. Curle, MD, associate professor of clinical anesthesiology and director, Center for Perioperative Medicine, University of Rochester Medical Center, Rochester, N.Y., and Jonathan S. Gal, MD, assistant professor of anesthesiology, Icahn School of Medicine at Mount Sinai, New York City, presented their perspectives on the PSH model during the 68th New York State Society of Anesthesiologists’ PostGraduate Assembly (PGA). - Dr. Jonathan Gal, Assistant Professor, Anesthesiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.anesthesiologynews.com/ViewArticle.aspx? d=Policy%2B%26%2BManagement&d_id=3&i=February+2015&i_id=1145&a_id=29326

The New York Daily News – February 15 In Honor of Heart Month, How to Keep Your Ticker in Tip-Top Form – Katie Charles An estimated 1 in 58 Americans are living with atherosclerosis — which works out to some 4.6 million people affected by the disease. “Atherosclerosis is a chronic inflammatory response involving plaque buildup in the cardiovascular system throughout the body,” says Joseph Sweeny, MD, the medical director of the new Lauder Family Cardiovascular Ambulatory Center at The Mount Sinai Hospital. “It's also the primary underlying cause for most heart attacks, stroke and peripheral arterial disease.” -Dr. Joseph Sweeny, Assistant Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Medical Director, The Lauder Family Cardiovascular Ambulatory Center at Mount Sinai Learn more: http://www.nydailynews.com/life-style/heart-month-article-1.2108744

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 17, 2015 Date: Tuesday, February 17, 2015 1:59:45 PM Attachments: ATT00001.txt

In the News February 17, 2015

Science Daily – February 12 Largest Genetic Blueprint of Obesity Revealed There are many reasons why people gain different amounts of weight and why fat is stored in different parts of their bodies. Now, researchers point to a genetic reason for a tendency to put on weight. Their findings, part of the largest-ever DNA probe into obesity were published in two papers in the journal Nature. The GIANT (Genetic Investigation of Anthropometric Traits) project netted more than 100 previously-undiscovered gene variants which play a part in obesity's complex processes. Senior author Ruth Loos, PhD, professor of preventive medicine at The Mount Sinai Hospital, and director of the Genetics of Obesity and related Metabolic Traits Program in the Charles Bronfman Institute for Personalized Medicine says "A major challenge now is learning about the function of these genetic variations and how they indeed increase people's susceptibility to gain weight. This will be the critical next step, which will require input from scientists with a range of expertise, before our new findings can be used towards targeted obesity prevention or treatment strategies." -Ruth Loos, PhD, Director of the Genetics of Obesity and Related Metabolic Traits Program at the Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.sciencedaily.com/releases/2015/02/150211131840.htm Additional Coverage: International Business Times: http://www.ibtimes.co.uk/largest-genome-studies-establish-obesity-links- genes-brain-1487632 Health Canal: http://www.healthcanal.com/metabolic-problems/obesity/60214-largest-ever-genome- wide-study-strengthens-genetic-link-to-obesity.html Endo Nurse: http://www.endonurse.com/news/2015/02/largest-ever-genome-wide-study-strengthens- geneti.aspx Harvard Medical School: http://hms.harvard.edu/news/beyond-diet-and-exercise Bariatric News: http://www.bariatricnews.net/?q=news/111853/giant-outcomes-strengthens-genetic-link- obesity Nature World News: http://www.natureworldnews.com/articles/12708/20150212/gaining-weight-is-all- in-the-genes.htm All4Women.com: http://www.all4women.co.za/307892/health/weight-loss-tips/study-confirms-genetic- link-to-weight-gain Stone Hearth Newsletters: http://www.stonehearthnewsletters.com/obesitys-genetic-component-new- evidence/genetics/

Los Angeles Times – February 13 Diet and Exercise Alone Are No Cure for Obesity, Doctors Say – Melissa Healy In a commentary published Thursday in the journal Lancet Diabetes and Endocrinology, four weight-loss specialists set out to correct what they view as the widespread misimpression that people who have become and stayed obese for more than a couple of years can, by diet and exercise alone, return to a normal, healthy weight and stay that way. "Once obesity is established, however, body weight seems to become biologically 'stamped in' and defended," wrote The Mount Sinai Hospital obesity specialist Christopher N. Ochner and colleagues from the medical faculties of the University of Colorado, Northwestern University and the University of Pennsylvania. -Christopher Ochner, PhD, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.latimes.com/science/sciencenow/la-sci-sn-eat-less-more-obesity-20150212- story.html Additional Coverage: The New York Daily News: http://www.nydailynews.com/life-style/health/lifestyle-won-cure-obesity- study-article-1.2114632 The Seattle Times: http://seattletimes.com/html/nationworld/2025702384_obesitystudyxml.html International Business Times Australia: http://au.ibtimes.com/diet-exercise-not-enough-fight-obesity- 1421831 Fox News via Live Science: http://www.foxnews.com/health/2015/02/13/why-exercise-and-diet-changes- may-not-be-enough-to-treat-obesity/ Medical Daily: http://www.medicaldaily.com/diet-and-exercise-arent-always-enough-fight-obesity-it- also-has-genetic-roots-322270 Apex Tribune: http://www.apextribune.com/why-diet-exercise-not-enough-beat-obesity/22802/ VOXXI: http://voxxi.com/2015/02/16/diet-exercise-no-weight-loss/

The National Herald – February 14 Caryn Schwab’s Commitment to People – Penelope Karageorge For more than a century, Mount Sinai Queens has provided a medical port in the storm for Astoria’s Greeks and Greek-Americans. The person at the top of the great medical facility comes as just as much of a surprise. Slender, blonde and utterly charming, Caryn Schwab could pass as “a lady who lunches.” Instead, she’s the tough-minded, imaginative, and compassionate Executive Director of Mount Sinai Queens. -Caryn Schwab, Executive Director, Mount Sinai Queens Learn more: http://www.thenationalherald.com/75449/ [Login Required]

The New York Times – February 17 Julianne Moore on Forging a Bond with Alzheimer’s Patients – Cara Buckley Julianne Moore was a late-ish add to the awards race, coming in quietly with her performance in the independent film “Still Alice,” about a high-achieving cognitive psychologist receiving a diagnosis of early onset Alzheimer’s. Now, after picking up a Golden Globe and a SAG Award, among other prizes, she’s a front-runner for the Oscar for best actress. With the help of Elizabeth Gelfand Stearns of the Alzheimer’s Association, she Skyped with women who had recently learned their diagnoses at a relatively young age; went to The Mount Sinai Hospital to talk with a leading researcher; and visited long-term-care facilities and support groups. -The Mount Sinai Hospital Learn more: http://carpetbagger.blogs.nytimes.com/2015/02/17/julianne-moore-on-forging-a-bond-with- alzheimers-patients/?_r=0 Additional Coverage: Fayetteville Observer: http://www.fayobserver.com/living/sunday_life/julianne-moore-goes-inside- alzheimer-s-in-still-alice/article_596b56cc-4395-536f-8c84-3de5e471898b.html

CBS News – February 13 Young Heart Transplant Patient on the Mend with Dog's Help – Kris Van Cleave A New York boy is celebrating Valentine's Day with a new heart this year. And his doctors are giving a dog named Ralph some of the credit. Eight-year-old Pablo Patino was born with congestive heart failure, and by last fall, his enlarged heart was deteriorating fast. "There were times he was so sick he may not have survived, so it's amazing," Irene Lytrivi, MD, a pediatric cardiologist at Kravis Children's Hospital at Mount Sinai, told CBS News. Pablo received a heart transplant in November. But after surgery, doctors say he needed something more than just modern medicine. That's when Ralph stepped in. The dog helped distract Pablo from the pain and encouraged him to get up and move. -Dr. Irene Lytrivi, Assistant Professor, Pediatrics, Cardiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.cbsnews.com/news/young-heart-transplant-patient-on-the-mend-with-dogs- help/ Additional Coverage: WCBS : http://newyork.cbslocal.com/2015/02/13/therapy-dog-gets-credit-for-helping-recovery-of- young-heart-transplant-patient/ WLNY: No Web Link Available WJZ: No Web Link Available KEYC: http://www.keyc.com/story/28108502/boy-recovers-from-heart-transplant-with-help-of-therapy- dog

CBS News – February 13 Hormone Replacement Therapy Raises New Cancer Concern – Jessica Firger While the synthetic hormones, estrogen and progestin, can work magic to stop hot flashes, decades of research has identified a strong link between Hormone Replacement Therapy and conditions such as heart disease, stroke and breast cancer. Now a new large scale analysis of 52 studies involving 21,488 women, published Thursday in The Lancet, finds even short-term use of these drugs correlated with a higher risk for ovarian cancer -- as much as 40 percent higher than women who don't take hormones. "This is the first big study like this to really come out and say ovarian cancer is an issue," Taraneh Shirazian, MD, an assistant professor of obstetrics, gynecology and reproductive science and a minimally invasive gynecological surgeon, told CBS News. - Dr. Taraneh Shirazian, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://www.cbsnews.com/news/hormone-replacement-therapy-ovarian-cancer-risk/

ABC News – February 13 This Couple Might Be Dead If They Hadn't Married One Another – Sydney Lupkin If Brian and Jeanne Gari hadn't gotten married, they said they'd probably be dead now. They pushed each other to go to the doctor, catching breast cancer and four blocked arteries. It started in 2012, just six months after their wedding, when Brian started to notice that his breathing wasn't quite right as he walked down the street. Jeanne, 57, a pediatric nurse, insisted that he see a cardiologist. When Brian went in for a stress test, he failed it and was rushed to the Mount Sinai St. Luke's Hospital for an electrocardiogram. A year and a half later, in December 2013, Jeanne was contemplating putting her mammogram off for the second year in a row, when Brian became angry with her. So she went. They discovered a mass, and shortly thereafter, Jeanne was diagnosed with stage one triple negative breast cancer. “She was very lucky that her husband had her come in to see me," said Sharon Rosenbaum- Smith, MD, a breast surgeon at Mount Sinai Roosevelt Hospital. - Dr. Sharon Rosenbaum Smith, Assistant Professor, Surgery, Icahn School of Medicine at Mount Sinai Learn more: http://abcnews.go.com/Health/couple-dead-married/story?id=28951325

Healthline – February 16 Delaying Vaccinations Is Not OK, Doctors Say – David Heitz A measles outbreak has been spreading like wildfire, shining an unfavorable spotlight on the anti- vaccination movement. In an interview with Healthline, Gail Shust, MD, a pediatric infectious disease specialist at the Kravis Children’s Hospital at Mount Sinai in New York City put it bluntly. “There’s a lot of misinformation out there, and people have this general notion that too many immunizations at once are overtaxing to the immune system,” she said. “But there’s no basis for that. That’s not real. It’s just kind of a general thing that people say, and for whatever reason it has stuck, and it’s preying upon the fears of parents.” - Dr. Gail Shust, Assistant Professor Medical Education, Pediatrics, Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: http://www.healthline.com/health-news/doctors-say-delaying-vaccinations-is-not-ok- 021615

Medpage Today – February 16 Warmth + Sugar = Less Vaccination Pain for Babies – Molly Walker Babies given radiant warmth plus a sucrose solution tolerated painful procedures better than babies only given sucrose, according to a small randomized, controlled trial. Discussant Ian Holzman, MD, chief of newborn medicine at the Kravis Children's Hospital at Mount Sinai in New York City, saw the merits of the study in helping to alleviate the pain of necessary vaccinations for babies. "There is some thought that repeated painful procedures as a baby change your behavior when you get older around painful stimuli," said Holzman. "Neonatal intensive care units and people caring for babies could probably add this to their armamentarium of preventing or decreasing pain in babies who get painful procedures." - Dr. Ian Holzman, Professor, Pediatrics, Newborn Medicine, Obstetrics, Gynecology, Reproductive Science, Icahn School of Medicine at Mount Sinai, Chief of Neonatal Medicine at the Mount Sinai Hospital Learn more: http://www.medpagetoday.com/Pediatrics/GeneralPediatrics/50043

Yahoo Health – February 17 How Long?! Menopause Hot Flashes Last Years Longer Than Previously Thought – Jenna Birch In the largest study of its kind, researchers looked into the symptoms of a racially, geographically and ethnically diverse group of 1,449 women enduring frequent hot flashes. The median length of time women endured the heat was 7.4 years.. According to Taraneh Shirazian, an assistant professor of obstetrics, gynecology and reproductive science at the Icahn School of Medicine at Mount Sinai in New York City, the results of this study are finally validating what docs see every day. “I’m not at all surprised,” she tells Yahoo Health. “For years, we’ve been hearing menopausal symptoms last only around three years, but in practice, we’ve seen them last for about a decade.” - Dr. Taraneh Shirazian, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: https://www.yahoo.com/health/how-long-menopause-hot-flashes-last-years-longer- 111285923478.html

Health – February 17 7 Safe Off-Label Uses for Over-The-Counter Meds – Hallie Levine Many familiar drugs and toiletries can pull double-duty, whether because they've got unintentionally helpful side effects or because their main ingredient is just a great multitasker. These expert-approved solutions might save you an emergency run to the pharmacy—or at the very least soothe a sore shoulder. Preparation H contains the vasoconstrictor phenylephrine, which shrinks swollen hemorrhoids. But Preparation H can also reduce the puffy signs of too-little sleep when applied under the eyes, said Joshua Zeichner, MD, assistant professor of dermatology at the Icahn School of Medicine at Mount Sinai in New York City. - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.health.com/health/gallery/0,,20899141,00.html Additional Coverage: Fox News via Health: http://www.foxnews.com/health/2015/02/17/7-safe-off-label-uses-for-over- counter-meds/

Cosmopolitan – February 15 Should You Get an IUD? – Cara Buckley There has been a lot written lately about why less than 5 percent of "contracepting" women under 30 use IUDs. Why so few when they are super safe, effective, and the favored birth control of ob-gyns? IUDs can be scary. It doesn't help that they have a rocky history. We've had IUD-like devices for about 100 years now, but truly safe and effective versions didn't make their debuts until pretty recently: 27 years ago for ParaGard, 14 years for Mirena. When you say "IUD" to your mom, she probably thinks of the Dalkon Shield, which was pulled from the market in the 1970s for causing injuries, infections, miscarriages, and 17 deaths. "There's a hangover from that period," says Laura MacIsaac, MD, director of family planning for the Mount Sinai Health System. People assume that IUDs are injury-causing nightmares, but uterine perforation is extremely rare. - Dr. Laura MacIsaac, Associate Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Director, Family Planning, The Mount Sinai Health System Learn more: http://www.cosmopolitan.com/health-fitness/a35806/should-you-get-an-iud/

Health – February 2015 3 Common Butt Problems, Solved – Hallie Levine If you notice blood in your poop or on the toilet paper, or itching and swelling around your anus, you may have hemorrhoids. The most common risk factor, says Steven Naymagon, MD, gastroenterologist at The Mount Sinai Hospital: constipation. Treatment is usually over-the-counter products with witch hazel or hydrocortisone to relieve swelling and/or itching, as well as soaking in a warm sitz bath. Also key: Slowly up your fiber intake to 25 to 30 grams a day, and drink lots of water. If that doesn't work, Dr. Naymagon adds, your doc can perform an in-office procedure known as a rubber band ligation, where she places a band around the hemorrhoid to cut off its circulation. - Dr. Steven Naymagon, Assistant Professor, Medicine, Gastroenterology, Icahn School of Medicine at Mount Sinai Learn more: http://www.health.com/health/article/0,,20883002,00.html

WCBS – February 16 Staying Safe in the Bitter Cold – Elise Finch Anyone who has to work outside or chooses to go outside during these bitter temperatures has to keep certain things in mind. Those who don’t take care may end up in the emergency room with hypothermia. “One of the ways your body loses heat is by cold air blowing across it, so that can lower your body temperature faster,” says Peter Shearer, MD, of The Mount Sinai Hospital. “You want to make sure that your skin is covered up well, that you’re wearing layers and well insulated fabrics.” -Dr. Peter Shearer, Assistant Professor, Emergency Medicine, Icahn School of Medicine at Mount Sinai Learn more: No Web Link Available

Time Warner Cable News – February 14 Fit Kids: Maintaining Oral Hygiene for Children – Jill Urban For some parents, getting their kids to take care of their teeth is like pulling teeth. But it is important. Proper oral hygiene at a young age sets the stage for healthy habits. “The focus right now is preventing cavities,” says Laurence Hyacinthe, DMD, a dentist at The Mount Sinai Hospital. She continues, “Having good habits from the beginning is the best thing you could do.” -Dr. Laurence Hyacinthe, Clinical Instructor, Dentistry, Icahn School of Medicine at Mount Sinai Learn more: http://www.ny1.com/nyc/bronx/fit-kids/2015/02/12/fit-kids--maintaining-oral-hygiene-for- children.html

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 13, 2015 Date: Friday, February 13, 2015 11:26:58 AM Attachments: ATT00001.txt

In the News February 13, 2015

CBS News – February 13 Diet and Exercise Not Enough, Obesity Experts Say – Jessica Firger A new paper published in the journal Lancet Diabetes & Endocrinology argues that it's high time for obesity to be recognized as a serious chronic disease with biological causes -- not just a result of poor eating habits and sedentary behavior. "Although lifestyle modifications may result in lasting weight loss in individuals who are overweight, in those with chronic obesity, body weight seems to become biologically 'stamped in' and defended," Christopher Ochner, PhD, lead author and Assistant Professor of Pediatrics and Psychiatry at the Icahn School of Medicine at Mount Sinai in New York, said in a press statement. -Christopher Ochner, PhD, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.cbsnews.com/news/diet-exercise-treatment-for-obese-patients/ Additional Coverage: Metro (UK): http://metro.co.uk/2015/02/12/obese-people-cant-lose-weight-by-dieting-and-exercise- doctors-claim-5060754/ Medical News Today: http://www.medicalnewstoday.com/articles/289339.php The Huffington Post Italy: http://www.huffingtonpost.it/2015/02/12/dieta-movimento- dimagrire_n_6670286.html [Article is in Italian] South China Morning Post: http://www.scmp.com/lifestyle/health/article/1711373/diet-and-exercise- alone-cant-lead-sustained-weight-loss-say-experts The Hindu: http://www.thehindu.com/sci-tech/health/obesity-is-a-chronic-treatmentresistant- disease/article6883128.ece Medical Xpress: http://medicalxpress.com/news/2015-02-experts-current-obesity-treatments.html 6 Minutes (Australia): http://www.6minutes.com.au/news/latest-news/why-chronic-obesity-is-so- difficult-to-cure [Login required] Odisha Samaya (India): http://odishasamaya.com/news/work-diet-not-adequate-drop-weight FremchTribune.com: http://frenchtribune.com/teneur/1524024-obesity-cannot-be-fought-just-dieting- and-exercise HIR24 (Hungary): http://www.hir24.hu/elet-stilus/2015/02/13/a-kronikusan-elhizott-embereken-nem- segit-a-dieta-es-a-torna/ [Article is in Hungarian]

Healthline News – February 12 Experts: Obesity Is Biologically 'Stamped In,' Diet and Exercise Won't Cure It – Brian Krans When humans had to forage for their greens and hunt for their proteins, a little extra meat on a person’s bones meant things were good. The biology of modern humans evolved under that model, but now that there’s an abundance of available calories, eating too much is a threat to the more than one third of Americans who are obese. Christopher N. Ochner, MD, an assistant professor of pediatrics and psychiatry at the Icahn School of Medicine at Mount Sinai in New York, argues these biological underpinnings help explain why obesity is nearly impossible to overcome by simply eating less and exercising more. “We’re still designed to consume as many calories as possible,” Ochner told Healthline. “There hasn’t been enough time to change our biology.” -Christopher Ochner, PhD, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.healthline.com/health-news/obesity-is-biologically-stamped-in-diet-and- exercise-wont-cure-it-021215

Medscape – February 13 Obesity Treatment Requires More Than Lifestyle Modification – Miriam E. Tucker Obesity is a complex medical problem that requires a multimodal approach beyond merely advising patients to go on a diet and exercise, four obesity experts say in a new opinion piece. "When treating obesity, mere recommendations for lifestyle change are most likely insufficient," the lead author, psychiatrist Christopher N Ochner, PhD, from the Icahn School of Medicine at Mount Sinai, New York, told Medscape Medical News. -Christopher Ochner, PhD, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/839759

Lincoln Journal Star – February 12 Dogs Improve The Mindset, Follow-Thru Of Cancer Patients, Study Finds A study, published in the Journal of Community and Supportive Oncology, found visits from therapy dogs and their trainers not only decreased anxiety and stress levels in cancer patients but also increased patient compliance with treatment -- resulting in better outcomes. “This study is the first such definitive study in cancer, and it highlights the merits of animal-assisted visits using the same scientific standards as we hold for the cancer treatment itself,” said Stewart Fleishman, MD, principal investigator and founding director of cancer supportive services at Mount Sinai Beth Israel. “Having an animal-assisted visit significantly improved their quality of life and ‘humanized’ a high-tech treatment,” he said. - Dr. Stewart Fleishman, Founding Director, Cancer Supportive Services, Mount Sinai Beth Israel Learn more: http://journalstar.com/lifestyles/family/dogs-improve-the-mindset-follow-thru-of-cancer- patients-study/article_d0957a39-092f-57c0-a4fb-61d89a5a0a39.html

Al Jazeera America – February 12 Could Ketamine Become The Next Great Depression Drug? – Timothy Bella Long used as an anesthetic and sedative in hospital rooms and framed in recent years as a harmful recreational club drug, the perception of ketamine is getting reinvented yet again. This time, through years of research, ketamine is showing promise as a tool for future depression treatments. And since 2012, studies from Yale University, Houston’s Baylor College of Medicine and New York’s Icahn School of Medicine at Mount Sinai found that ketamine is overwhelmingly successful for treatment-resistant patients. - Icahn School of Medicine at Mount Sinai Learn more: http://america.aljazeera.com/watch/shows/america-tonight/articles/2015/2/12/Ketamine.html

ABC News – February 12 8-Year-Old Buddies Return to Hospital for Valentine's Day Heart Surgery Reunion – Sydney Lupkin To see 8-year-olds Siobhan and Michelle dancing in their Valentine's Day outfits, you'd never know that they underwent open heart surgeries before they could walk. For them, visits to the hospital aren't so scary. That's because the girls -- and their families -- have always had each other. Both girls go to The Mount Sinai Hospital for regular scans and checkups. They call each other "frousins," meaning friends who are like cousins. But on Wednesday, the girls were back at the hospital for a happy reason: the Valentine's Day reunion. The girls and their families reunited with their cardiologist Shubhika Srivastava, MD. - Dr. Shubhika Srivastava, Associate Professor, Pediatrics, Cardiology, Icahn School of Medicine at Mount Sinai Learn more: http://abcnews.go.com/Health/year-buddies-return-hospital-valentines-day-heart- surgery/story?id=28893534 Additional Coverage: WRIC: http://wric.com/2015/02/13/8-year-old-buddies-return-to-hospital-for-valentines-day-heart- surgery-reunion/

Healthday – February 13 Meat-Heavy, High-Acid Diet Poses Risk for Those with Kidney Disease: Study – Alan Mozes Patients struggling with chronic kidney disease who routinely consume meat-rich, highly acidic diets may boost their risk for kidney failure, a new study suggests. Experts have long suspected that a highly acidic diet -- one higher in meat, low in fruits and vegetables -- might aggravate this state. The theory has been supported by "randomized studies in which alkali supplementation slowed the loss of kidney function in patients with chronic kidney disease," explained Jaime Uribarri, MD, a professor of nephrology at the Icahn School of Medicine at Mount Sinai, in New York City. -Dr. Jaime Uribarri, Professor, Medicine, Nephrology, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/diseases-and-conditions-information-37/misc-kidney- problem-news-432/meat-heavy-high-acid-diet-poses-risk-for-those-with-kidney-disease-696334.html Additional Coverage: U.S. News & World Report: http://health.usnews.com/health-news/articles/2015/02/13/meat-heavy-high- acid-diet-poses-risk-for-those-with-kidney-disease-study

Wire Image – February 11 2015 Kravis Children's Hospital at Mount Sinai Reunion Party – Desiree Navarro Miss USA Nia Sanchez attends 2015 Kravis Children's Hospital at Mount Sinai to celebrate life at their annual Reunion Party at Mount Sinai Medical Center on February 11, 2015 in New York City. - Dr. Shubhika Srivastava, Associate Professor, Pediatrics, Cardiology, Icahn School of Medicine at Mount Sinai - Dr. Ira Parness, Professor, Pediatrics, Cardiology, Icahn School of Medicine at Mount Sinai, Chief, Pediatric Cardiology, The Mount Sinai Hospital Learn more: http://www.wireimage.com/search/#events?q=%5B537108161%5D&s=3

Medical Daily – February 12 Dermatitis Rates Increasing As Hospital Hand Washing Policies Seek To Sanitize – Chris Weller A new study from the University of Manchester has found irritant dermatitis rates are rising in hospitals that employ strict hand washing policies. After round-the-clock shifts, workers prompted to wash their hands before, during, and after attending to individual patients, find their clean hands rubbed raw. Ultimately, the best solution may simply be to invest in a trusty moisturizer, says Cameron Rokhsar, MD, assistant clinical professor of dermatology at Mount Sinai Health Systems. “The heavier the moisturizer the better it works,” he told Medical Daily. “To that effect, ointments work better than creams, which work better than lotions. In severe cases, we can prescribe steroid medications to calm the skin down.” - Dr. Cameron Rokhsar, Assistant Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.medicaldaily.com/dermatitis-rates-increasing-hospital-hand-washing-policies- seek-sanitize-321998

Yahoo Beauty – February 13 Is Sex Good For Your Skin? – Kristin Booker As Valentine’s Day approaches there’s a lot of focus on February 14th and the amount of sexy time that’s about to go down. If you’re planning to get close with someone you love, you might get more benefits than you think: it turns out that sex also has benefits for your skin. “It’s like the benefits from massage,” explains Jeannette Graf, MD, an assistant clinical professor of dermatology at The Mount Sinai Hospital. ”It’s enjoyable, and you release a lot of endorphins from the feeling of touch, which is a benefit in itself. Sweat also helps with detoxification and calorie burn, and the extra blood flow also helps with lymphatic drainage,” she says. - Dr. Jeannette Graf, Assistant Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: https://www.yahoo.com/beauty/is-sex-good-for-your-skin-110895695468.html

Fusion – February 12 Feeling Moody? You Could Have Cyclothymia – Isha Aran Cyclothymia is a mild mood disorder that causes emotional ups and downs. One minute you feel on top of the world, the next you’re struggling to make it through the day. While cyclothymia is a mood disorder, some people simply have a “cyclothymic personality”—putting it on the spectrum of personality disorders. Igor Galynker, director of the Family Center for Bipolar Disorder at Mount Sinai Beth Israel in New York, told Fusion that he finds referring to the condition as a “cyclothymic temperament” useful. The line between personality and mood disorder is often blurred, he said, and it takes some finesse to recognize the difference between the two. - Dr. Igor Galynker, PhD, Professor, Psychiatry, Icahn School of Medicine at Mount Sinai, Director, Division of Biological Psychiatry, Mount Sinai Beth Israel Learn more: http://fusion.net/story/46586/feeling-moody-you-could-have-cyclothymia/

Time Warner Cable News – February 11 Fit Kids February: Concussions in Children – Erin Billups There are different schools of thought on how children and teens should be treated for concussions. At the heart of the dilemma, just how much rest kids should get after a concussion and when they should return to school. It’s agreed that rest should follow a concussion, but how much rest and for how long are still being explored by head-trauma experts. "There’s a wide variation in both the way that kids are treated in the return to learn, so returning to school after a concussion, and also return to play, returning to sports and other activities after concussion,” says Joshua Cohen, MD, a neurologist at Mount Sinai Roosevelt. This spring Cohen and other experts in the concussion field and in education, hope to provide good evidence-based guidelines for how to manage a child after concussion, starting with a conference at The Mount Sinai Hospital. - Dr. Joshua Cohen, Assistant Professor, Neurology, Icahn School of Medicine at Mount Sinai Learn more: http://www.ny1.com/nyc/queens/fit-kids/2015/02/11/fit-kids--experts-work-toward- standardized-concussion-treatment-for-children.html

Family Circle – March 2015 Beauty Tips from Dermatologists Q: My dark circles look worse than ever. How can I get rid of them, or at least cover them up? A: Dab on an eye cream in the morning and evening that contains vitamin C or K, both of which help reduce pigmentation. Keep the product in the fridge – the cool temperature helps reduce puffiness, says Joshua Zeichner, MD, assistant professor of dermatology at The Mount Sinai Hospital in New York City. - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: No Web Link Available

XaLuan.com – February 13 These Foods are Good for You, But Dangerous if Eaten Too Much These are nutritious foods that you do not need to give up. Just remember to eat certain amounts, in moderation. Oranges and tomatoes are delicious but are two highly acidic fruits, says Gina Sam, MD, Director of the Mount Sinai Gastrointestinal Motility Center in the United States. The increased amount of acid from eating too many oranges or tomatoes can lead to reflux. - Dr. Gina Sam, Assistant Professor, Medicine, Gastroenterology, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Gastrointestinal Motility Center at the Mount Sinai Hospital Learn more: http://www.xaluan.com/modules.php?name=News&file=article&sid=1090932 [Article is in Vietnamese]

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 12, 2015 Date: Thursday, February 12, 2015 12:36:14 PM Attachments: ATT00001.txt

In the News February 12, 2015

Breast Cancer News – February 11 Folate Modulated Genes May Affect Differences in Breast Cancer Risk Between African-Americans and European-Americans – Patricia Inacio, PhD In a new study researchers identified differences in genetic variants associated with breast cancer risk between European American and African-American women. Notably, these changes are modulated with dietary folate intake and may be a cause for increased incidence of aggressive breast cancer in African-American women. The study was published in the International Journal of Cancer. The study was conducted by a team of researchers at the Roswell Park Cancer Institute (RPIC) and collaborators at the Rutgers Cancer Institute of New Jersey and the Icahn School of Medicine at Mount Sinai School of Medicine. - Icahn School of Medicine at Mount Sinai Learn more: http://breastcancer-news.com/2015/02/11/folate-modulated-genes-may-affect-differences- in-breast-cancer-risk-between-african-americans-and-european-americans/

Healio Endocrinology– February 12 Diet, Exercise Not Effective for Permanent Obesity Treatment – Amber Cox Researchers suggest that obesity is a chronic disease with a number of biological causes that make it impossible to be cured with diet and exercise alone in a recently published comment in The Lancet Diabetes & Endocrinology. According to the researchers lifestyle changes are not enough to override the fat-loss defense. “Although lifestyle modifications may result in lasing weight loss in individuals who are overweight, in those with chronic obesity, bodyweight seems to become biologically ‘stamped in’ and defended,” Christopher N. Ochner, PhD, assistant professor of pediatrics and psychiatry at Icahn School of Medicine at Mount Sinai and the New York Obesity Nutrition Research Center at Columbia University Medical Center, said in a press release. -Christopher Ochner, PhD, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.healio.com/endocrinology/obesity/news/online/%7Bd3addbbc-6a68-4638-9dae- 903f6f6aa1b7%7D/diet-exercise-not-effective-for-permanent-obesity-treatment Additional Coverage: The Daily Mail: http://www.dailymail.co.uk/news/article-2950087/Exercise-diet-not-lose-weight- Doctors-treat-obesity-chronic-disease-biological-factors-cause-it.html WebMD: http://www.webmd.boots.com/diet/news/20150212/is-obesity-wired-in Live Science: http://www.livescience.com/49782-obesity-treatments-biology.html The Independent (UK): http://www.independent.co.uk/life-style/health-and-families/health- news/theres-no-point-telling-obese-people-to-exercise-more-doctors-claim-10039641.html Bristol Post (UK): http://www.bristolpost.co.uk/New-research-claims-diet-exercise-help-obese/story- 26014958-detail/story.html Scotland TV: http://news.stv.tv/scotland/310031-giving-advice-to-obese-individuals-to-eat-less-is- ineffective/ The Journal (Ireland): http://www.thejournal.ie/obesity-diet-weight-loss-1932509-Feb2015/

Medpage Today – February 11 So You Can Use a Clot Retriever? Great, but Not Enough – Crystal Phend With confirmation from three trials that endovascular clot retrieval with thrombolysis helps outcomes in large vessel ischemic strokes, there's an immediate mandate for practice. But achieving that level of quality is likely to be a real challenge even for centers with the capability, J Mocco, MD, told MedPage Today in an interview after presentation of the ESCAPE, EXTEND-IA, and SWIFT PRIME trial data here at the American Heart Association's International Stroke Conference. Mocco, director of cerebrovascular surgery at The Mount Sinai Hospital in New York City, laid out the issues to consider in developing a program in this Q&A interview with MedPage Today. - Dr. J Mocco, Director of Cerebrovascular Surgery, Department of Neurological Surgery, Mount Sinai Health System Learn more: http://www.medpagetoday.com/MeetingCoverage/ISCNeuroEdition/49982

The New York Times– February 11 The Pillow Cure – Penelope Green For years, the standard pillow for those with neck issues has been a crudely formed foam number, which is about as sexy as the cervical collar that is its daytime mate. There are a few data sets to roughly gauge the size of the market for a product that would address the sleep/pain nexus. In 2012, 14 percent of adult Americans said they had neck pain within a three-month period; in 2010, another survey noted that there were more than 10 million visits to doctors’ offices for complaints related to neck pain. As it turns out, said Robert Gotlin, MD, director of orthopedic and sports rehabilitation at Mount Sinai Beth Israel, we are designed for failure. “The fact is, from age 25 on, this process of failure begins,” he continued cheerfully. As far as pillows are concerned, he said: “The real answer is, there is no answer. - Dr. Robert Gotlin, Associate Professor, Rehabilitation Medicine, Orthopaedics, Icahn School of Medicine at Mount Sinai, Director, Orthopaedic and Sports Rehabilitation, Mount Sinai Beth Israel Learn more: http://www.nytimes.com/2015/02/12/garden/the-pillow-cure.html?_r=0

WABC – February 11 Pediatric Heart Patients Reunite With Staff at The Mount Sinai Hospital – Sade Baderinwa There was a touching reunion in Manhattan Wednesday night for hundreds of pediatric heart patients. It was an annual reunion party for kids treated at The Mount Sinai Hospital's Kravis Children's Hospital. "This is the time when we see the patients the way we want to see them, not in the office on the examining table or having an ultrasound or procedure, but doing things that normal kids do, enjoying the fruits of our labor and their parents' labor," said Ira Parness, MD, of The Mount Sinai Hospital. - Dr. Ira Parness, Professor, Pediatrics, Cardiology, Icahn School of Medicine at Mount Sinai, Chief, Pediatric Cardiology, The Mount Sinai Hospital Learn more: http://7online.com/health/pediatric-heart-patients-reunite-with-staff-at-mount-sinai- hospital/514163/

Today.com – February 11 Singer Sophie B. Hawkins Joins Growing Club: Moms Over 50 – Susan Donaldson James The singer, whose hits include “Damn I Wish I Was Your Lover” and “As I Lay Me Down,” is expecting a girl in July, after undergoing in vitro fertilization with donor sperm and her own eggs, which she froze at 31. And many doctors ask: Why not? “We see this a lot,” said Joanne Stone, MD, director of fetal medicine at The Mount Sinai Hospital in New York City. “Women are delaying child-rearing, reproductive technology has improved, and donor eggs are more acceptable.” Jacques Moritz, MD, director of gynecology at Mount Sinai Roosevelt Hospital in New York City, said about 25 percent of his practice is older women. - Dr. Jacques Moritz, Director, Gynecology, Mount Sinai St. Luke’s and Mount Sinai Roosevelt, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai - Dr. Joanne Stone, Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Director, Maternal Fetal Medicine, The Mount Sinai Hospital Learn more: http://www.today.com/health/singer-sophie-b-hawkins-joins-growing-club-moms-over-50- 2D80486150

Healthline News – February 11 Do Baby Boomers Need to be Revaccinated? According to the Immunization Action Coalition, Baby Boomers should be receiving at least one dose of the MMR vaccine. Audrey Chun, MD, an associate professor in the Department of Geriatrics and Palliative Medicine at the Icahn School of Medicine at Mount Sinai, said older adults are at a low risk for contracting measles. “Most people born before 1957 were exposed to at least two major measles outbreaks, which confers immunity,” she said. Once a person has had the measles, they are immune for life. Samuel Altstein, DO, medical director of the Mount Sinai Beth Israel Medical Group, said about 1 in 10 adults who did not receive the entire series of vaccine shots are no longer protected “due to a decline in their measles antibody level.” -Dr. Audrey Chun, Director, Martha Stewart Center for Living and Vice Chair, Clinical Programs Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai -Dr. Sam Altstein, Medical Director, Mount Sinai Beth Israel Medical Group Learn more: http://www.healthline.com/health-news/some-adults-need-to-be-revaccinated-against- measles-021115#1

Healthline News– February 12 Is da Vinci Robotic Surgery a Revolution or a Ripoff? – Cameron Scott Laparoscopic surgery has proven to be a significant medical advance, turning major surgeries that kept patients in the hospital for several days and left big scars behind into fairly minor procedures. “I can’t tell you how many patients come in who say, ‘I want robotic surgery with a laser’ — and they’ll find somebody to do that,” said Eric Genden, MD, an ear, nose, and throat surgeon at The Mount Sinai Hospital in New York. “This is a beautiful illustration of how American medicine and the patients tend to become enamored of technology without ever really asking the question, ‘What are we getting for the technology?’” -Dr. Eric Genden, Professor, Neurosurgery, Otolaryngology, System Cahir, Otolaryngology, Icahn School of Medicine at Mount Sinai, Site Chair, Otolaryngology, Mount Sinai Roosevelt, Mount Sinai St. Luke’s Learn more: http://www.healthline.com/health-news/is-da-vinci-robotic-surgery-revolution-or-ripoff- 021215#1

The New York Daily News – February 12 Alcohol’s Health Benefits Grossly Overestimated: Study – Meredith Engel Bottoms down — alcohol isn’t as good for health as scientists have led us to believe. In reality, any benefits once conferred to light drinking may simply be a statistical anomaly, a new study reveals. But not every doctor says you should empty out your wine bottles just yet. “We know biologically why alcohol has benefits,” said Merle Myerson, MD, a cardiologist at The Mount Sinai Hospital. “This certainly sounds like an interesting study and bears further research ... (but) I certainly cannot dismiss some benefits of alcohol.” - Dr. Merle Myerson, Assistant Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, the Mount Sinai Roosevelt and St. Luke’s Cardiovascular Disease Prevention Program Learn more: http://www.nydailynews.com/life-style/health/alcohol-health-benefits-grossly- overestimated-study-article-1.2112474

The Los Angeles Times – February 11 For Most Strokes, Clot-Retrieval Device Boosts Effectiveness of Drug Treatment – Melissa Healy In most patients suffering a potentially devastating ischemic stroke, the added use of a medical device designed to retrieve the blockage and restore flow of blood to the brain reduces rates of death and disability, four new studies have demonstrated. Both clinical trials described in the New England Journal of Medicine were ended early when it became clear that the addition of clot-retrieval devices to clot- dissolving medication was superior in treating ischemic stroke when compared with clot-dissolving medication alone. “These are overwhelmingly, unequivocally positive numbers," said J Mocco, MD, Director of Cerebrovascular Surgery at the Mount Sinai Health System in New York City. - Dr. J Mocco, Director of Cerebrovascular Surgery, Department of Neurological Surgery, Mount Sinai Health System Learn more: http://www.latimes.com/science/sciencenow/la-sci-sn-stroke-treatment-better-20150211- story.html

SheKnows – December 9 Prevent 8 Common Diseases with These Rockstar Superfoods – Kristen Fischer According to a new study in BMC Medicine that followed about 200,000 people over as much as three decades, low- and high-fat dairy consumption was not linked to having a risk for type 2 diabetes. Alexandra Rothwell, R.D., a nutrition coordinator at the Dubin Breast Center at The Mount Sinai Hospital, also recommends adding cinnamon to your diet. It is essential to eat a well-rounded diet. "No one food can directly prevent a medical condition or disease, though a combination of healthy, nutrient- dense foods including vegetables, fruits, whole grains, lean protein and low-fat dairy can have a protective effect against many cancers and chronic conditions," said Rachel Neifeld, a registered dietitian at Friedman Diabetes Institute at Mount Sinai Beth Israel. -Alexandra Rothwell, RD, Nutrition Coordinator, Dubin Breast Center at The Mount Sinai Hospital -Rachel Neifeld, RD, Friedman Diabetes Institute, Mount Sinai Beth Israel Learn more: http://www.sheknows.com/health-and-wellness/articles/1065803/prevent-disease-with- superfoods

ACC in Touch Blog – February 11 Empowering Women to Attain Careers in Science: An Update From the ACC’s NY Chapter WIC Meeting – Natalie Bello, MD, MPH and Johanna Paola Contreras, MD, MSc, FACC The ACC New York State Chapter of the ACC’s Women in Cardiology (WIC) Member Section recently hosted its annual networking event at the New York Athletic Club in Manhattan. The gathering was a unique mix of women at all stages of their careers from fellows in training and junior faculty through more senior women, representing both private practice and academics. Over a delightful spread of heart healthy food and beverages, conversations ranged from starting a job search or running a practice in today’s health care environment to catching up with old friends and making new ones. -Dr. Johanna Contreras, Assistant Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai Learn more: http://blog.acc.org/post/empowering-women-to-attain-careers-in-science-an-update-from- the-accs-ny-chapter-wic-meeting/

Harper’s Bazaar – February 11 7 Dermatologists & Plastic Surgeons Weigh in on Botox – Alexandra Tunell When it comes to Botox, everyone's got an opinion. We asked the experts: How young is too young? "Most women under the age of 23 maybe even 25 do not typically need Botox." —Dr. Stafford Broumand, Plastic Surgeon and Associate Clinical Professor of Plastic Surgery at The Mount Sinai Hospital -Dr. Stafford Broumand, Associate Clinical Professor, Surgery, Icahn School of Medicine at Mount Sinai Learn more: http://www.harpersbazaar.com/beauty/skin-care/advice/a9948/plastic-surgeons-on-botox/

WCBS TV – February 11 The Frozen Zone – Kristine Johnson More and more people are venturing into the frozen zone, spending two to three minutes in chambers filled with freezing nitrogen gas up to 228 degrees below zero. The freezing temperatures shock the system and that is said to stimulate the immune system. The treatment was developed in Europe to treat pain related to fibromyalgia, arthritis, and other ailments. But pain management specialist Houman Danesh, MD, warns there are precautions that must be taken. He says, “If you have high blood pressure, poor circulation in your fingers, asthma, blood clots or are pregnant, it is not something you should do.” - Dr. Houman Danesh, Assistant Professor, Anesthesiology, Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai Learn more: No Web Link Available

Closer – February 16 Look Your Most Beautiful Q: I heard oatmeal is really good for your skin. Can I use the oatmeal in my cupboard to make an at- home mask? A: “Yes, antioxidants in oatmeal rejuvenate skin!” says NYC-based dermatologist Gary Goldenberg, MD. - Dr. Gary Goldenberg, Assistant Professor, Dermatology, Pathology, Icahn School of Medicine at Mount Sinai Learn more: No web link available

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 11, 2015 Date: Wednesday, February 11, 2015 12:02:55 PM Attachments: ATT00001.txt

In the News February 11, 2015

Prostate Cancer News – February 10 Researchers Find Gene That Can Regulate Prostate Cancer Development – Ana De Barros, PhD Recent results from Icahn School of Medicine at Mount Sinai researchers have shown that two approved cancer drugs have the capacity to turn on a gene responsible for cancer cells’ dormancy. In the study published in Nature Communications, the research team found that the NR2F1 gene works as a regulator of cancer cell dormancy or proliferation, depending on whether it is turned on or off. “Our results explain why some tumor cells scattered through the body are committed to remaining harmless for years, while others cause active disease,” said Julio A. Aguirre-Ghiso, PhD. “Azacytidine and retinoic acid, the latter a form of vitamin A, prevented tumor cells from rapidly multiplying, restored normal cell function, and activated several tumor suppressor genes that are often turned off in tumors,” added study co-leader Maria Soledad Sosa, PhD, - Julio Aguirre-Ghiso, PhD, Professor, Medicine, Hematology and Medical Oncology, Otolaryngology, Oncological Sciences, Icahn School of Medicine at Mount Sinai -Maria Sosa, PhD, Postdoctoral Fellow, Hematology, Icahn School of Medicine at Mount Sinai Learn more: http://prostatecancernewstoday.com/2015/02/10/researchers-find-gene-that-can-regulate- prostate-cancer-development/

Here Is The City Business – February 10 How This Illegal Substance Crushed My Trading Skills – Turney Duff Recently, a study came out from a team of researchers at the Icahn School of Medicine at Mount Sinai that showed cocaine use leads to bad decision-making. They recorded the brain activity of 50 cocaine users and 25 nonusers while they played a gambling game. The scientists were specifically examining the signals in the brain that help humans predict the possible rewards and punishments that might result from a decision. - Icahn School of Medicine at Mount Sinai Learn more: http://hereisthecity.com/en-gb/2015/02/10/how-cocaine-crushed-my-trading-skills/

Crain’s New York – February 11 Roosevelt to add MRI – Jonathan LaMantia Mount Sinai Roosevelt Hospital will start construction on a second MRI unit in March, following approval by the state Department of Health. The $4 million project will improve the hospital’s imaging capabilities, particularly in urology and orthopedics, said Alex Kagan, MD, site chair of Roosevelt’s radiology department. Tim Day, Roosevelt’s chief operating officer, said the additional MRI will give the facility more flexibility to cater to its ambulatory-surgery services. “With the one MRI, we were required to meet the needs of inpatient and emergency department patients as a priority,” Mr. Day said. -Timothy Day, Chief Operating Officer, Mount Sinai Roosevelt -Dr. Alexander Kagan, Senior Faculty, Radiology, Icahn School of Medicine at Mount Sinai, Site Chair, Department of Radiology, Mount Sinai Roosevelt Learn more: http://www.crainsnewyork.com/article/20150211/PULSE/150219980/startup-helps-you- watch-that-mouth#

The New York Times – February 10 Doulas, a Growing Force in Maternity Culture, Seek Greater Acceptance – Anemona Hartocollis Doulas are a growing force in the ever-changing culture of maternity, at once a manifestation of the growing demand for personal service (the doorman, the yoga teacher, Amazon Prime) and a backlash against the perceived overmedicalization of birth, with its high rates of cesarean sections. Some doctors say they understand how doulas fill a need in an impersonal hospital setting, and at the very least, feel obliged to honor their presence because they are what the patients want. “Having a baby in New York City is a very lonely thing,” Jacques Moritz, MD, an obstetrician at Mount Sinai Roosevelt hospital in Manhattan, said. “A doula is like a personal trainer. Not that you can’t do it yourself; it’s just nicer if you have a personal coach for it.” - Dr. Jacques Moritz, Director, Gynecology, Mount Sinai St. Luke’s and Mount Sinai Roosevelt, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://www.nytimes.com/2015/02/11/nyregion/doulas-the-latest-wave-in-maternity- culture-are-organizing-for-more-recognition.html?_r=1&assetType=nyt_now

Indiana Gazette via The New York Times – February 10 The Dangers of Vaccine Denial – Nicholas Kristof In reporting on poverty worldwide, I’ve seen how much vaccines improve human well-being. I understand how troglodytes in the Taliban or Boko Haram can be suspicious of vaccines, but politicians here in affluent, well-educated America? Moms and dads in Santa Monica? Philip J. Landrigan, MD, the chairman of the department of preventative medicine at the Icahn School of Medicine at Mount Sinai, says that there may be environmental factors linked to autism, but these relate to endocrine disrupting chemicals in consumer products, not to vaccines. - Dr. Philip Landrigan, Professor and System Chair, Preventative Medicine, Professor, Pediatrics, Dean for Global Health, Icahn School of Medicine at Mount Sinai Learn more: https://www.indianagazette.com/news/opinions/commentary-the-dangers-of-vaccine- denial,21475253/

International Business Times – February 10 Health Care: Walk-In Retail Clinics Burgeoning Source of Treatment – Elizabeth Whitman No longer are retail pharmacies merely places to purchase medicine. Now, they are sources of medical care, too. Major retailers in the U.S. are increasingly offering health care services in the form of walk-in retail clinics in their stores. This market-driven phenomenon has been widely hyped as more patients seek faster and more convenient care, but health care experts have expressed doubt these clinics’ have the ability to provide health care to those who need it most. Yasmin Meah, MD, director of the East Harlem Health Outreach Partnership, a free clinic run by students at the Icahn School of Medicine at Mount Sinai in New York, said her clinic’s patients were too impoverished and in too poor health to seek out care at retail clinics. - Dr. Yasmin Meah, Associate Professor, Medical Education, Medicine, General Internal Medicine, Geriatrics and Palliative Care, Icahn School of Medicine at Mount Sinai Learn more: http://www.ibtimes.com/health-care-walk-retail-clinics-burgeoning-source-treatment- 1811722

Becker’s Spine Review – February 10 Collaborative Healthcare — Most Exciting Partnerships in Spine – Laura Dyrda "Partnerships" is the name of the game in healthcare today. Different entities are aligning, collaborating and merging to better serve patients and make the United States' healthcare system more sustainable. Spine is no different. There are several examples of spine surgeons’ collaboration today, some that have been around for decades while others are unique to the 21st century. But while industry relationships are becoming more difficult, clinical relationships are becoming easier and more common. They are centered around similar quality and cost saving goals. "Surgeons are partnering with institutions more than in the past and moving toward cost-sharing," says Sheeraz Qureshi, MD, MBA, Orthopedic Surgeon, Minimally Invasive Spinal Surgery, Icahn School of Medicine at Mount Sinai in New York City. - Dr. Sheeraz Qureshi, Associate Professor, Orthopaedics, Icahn School of Medicine at Mount Sinai Learn more: http://www.beckersspine.com/orthopedic-spine-practices-improving-profits/item/24292- collaborative-healthcare-most-exciting-partnerships-in-spine.html

Healio Endocrinology – February 3 Health Care Utilization among Adults Diagnosed with Diabetes Differs by Age – Derek LeRoith The use of selected medical care services recommended for adults diagnosed with diabetes to manage glucose, obtain preventative care and treat complications varies by age, according to a report released by the CDC. The recent report by the CDC’s National Center for Health Statistics (NCHS) shows, once again, that the incidence of diabetes increases with age. Interestingly, it also shows that these older patients with diabetes are more likely to have medical care as indicated by increased doctors’ visits and the use of medications. - Dr. Derek LeRoith, Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://www.healio.com/endocrinology/diabetes/news/online/%7B6f3a4934-76e2-475f-a9bb- a6a393f650c7%7D/health-care-utilization-among-adults-diagnosed-with-diabetes-differs-by-age

Yahoo Health – February 10 With Yoga, 'I Felt My Body Change': Why So Many Americans Are Turning to Complementary Medicine – Jenna Birch When I was diagnosed with fibromyalgia four years ago, my doctors prescribed a trifold regimen to treat my chronic pain: medication, cognitive-behavioral therapy, and exercise. Yoga, in particular, was the recommendation for my aching muscles and joints. I’m not alone in turning to something beyond a little orange bottle to manage my health— according to a new report from the Center for Disease Control and Prevention’s National Center for Health Statistics, roughly a third of the country utilizes some sort of complementary medicine approach. The evidence supporting complementary medicine is real and growing, says Houman Danesh, MD, director of Integrative Pain Management at The Mount Sinai Hospital. “It’s no longer hokey,” he tells Yahoo Health. - Dr. Houman Danesh, Assistant Professor, Anesthesiology, Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.yahoo.com/health/with-yoga-i-felt-my-body-change-why-so-many- 110637868932.html

Yahoo Parenting– February 10 Surfer Bethany Hamilton’s Adorable ‘Baby on Board’ Announcement – Jennifer O’Neill Oh boy, pro surfer Bethany Hamilton is expecting a baby. The athlete—, whose amazing return to the sport after a vicious shark attack left her with one arm at age 13, inspiring the book and then movie Soul Surfer — shared the rad news that she’s having a son this June in an adorable video on her website on Sunday. “I’ve been surfing throughout my whole pregnancy,” says Hamilton. “I plan to surf as long as I can.” Once she feels too big to continue, she adds, “Maybe I’ll just, like, mellow it out and spend more time swimming.” That’s a smart plan, according to Isabel Blumberg, MD, of The Mount Sinai Hospital in New York City. “Turning to swimming is a great idea,” she says. “It’s the perfect exercise. There’s no pressure on your joints.” A bonus, according to Shari Brasner, MD, is that “she can swim until the day she goes into labor.” -Dr. Isabel Blumberg, Clinical Instructor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai -Dr. Shari Brasner, Assistant Clinical Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: https://www.yahoo.com/parenting/surfer-bethany-hamiltons-adorable-baby-on-board- 110642203112.html

OZY – February 11 The Best-Kept Secret on Wall Street Might Be Therapy – Farah Halime It’s been six years since the global financial crisis sent heart rates soaring, but that was just the beginning for some traders, bankers and financial analysts, whose stress levels are still high. More is being demanded of them due to ongoing job cuts on Wall Street, and concerns are growing over the plummeting price of oil, deflation and increasingly volatile stock markets. “The money situation got scary,” says Anne Ziff, clinical assistant professor at the Icahn School of Medicine at Mount Sinai and a New York-based therapist. She saw divorce rates hit between 30 and 40 percent among her clients and is now creating a group therapy program for those in the financial industry. - Anne Ziff, Assistant Clinical Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.ozy.com/fast-forward/the-best-kept-secret-on-wall-street-might-be- therapy/38627

Time Warner Cable News – February 11 Fit Kids February: Concussions in Children – Erin Billups There are different schools of thought on how children and teens should be treated for concussions. At the heart of the dilemma, just how much rest kids should get after a concussion and when they should return to school. It’s agreed that rest should follow a concussion, but how much rest and for how long are still being explored by head-trauma experts. "There’s a wide variation in both the way that kids are treated in the return to learn, so returning to school after a concussion, and also return to play, returning to sports and other activities after concussion,” says Joshua Cohen, MD, a neurologist at Mount Sinai Roosevelt. This spring Cohen and other experts in the concussion field and in education, hope to provide good evidence-based guidelines for how to manage a child after concussion, starting with a conference at The Mount Sinai Hospital. - Dr. Joshua Cohen, Assistant Professor, Neurology, Icahn School of Medicine at Mount Sinai Learn more: No Web Link Available

HealthPlans.com– February 4 Expert Interview with Christopher Ochner on Obesity in America – Susan Jennings In the U.S., obesity has reached epidemic proportions. It kills over 111,000 people annually, shortens the lifespan by five to 20 years, and results in $150 billion in annual health-related expenditures, says Christopher N. Ochner, PhD, co-chair of the Public Affairs Committee for The Obesity Society. -Christopher Ochner, PhD, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.healthplans.com/expert-interview-christopher-ochner-obesity-america/

Main Street – December 11 FDA Improves Drug Risk Disclosures for Women Who Are Pregnant or Breastfeeding – S.Z. Berg Pregnant women and those who are breastfeeding their babies, along with their prescribing doctors, will soon have better information on which to base their medication choices. Currently, prescription drug risk for pregnant and lactating women is based on letter classifications – A, B, C, D and X. “These categories are often not helpful in providing detailed information relevant to making decisions about use in pregnancy and lactation,” said Joanne Stone, MD, director of maternal fetal medicine at The Mount Sinai Hospital. - Dr. Joanne Stone, Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Director, Maternal Fetal Medicine, The Mount Sinai Hospital Learn more: http://www.mainstreet.com/article/fda-improves-drug-risk-disclosures-for-women-who- are-pregnant-or-breastfeeding

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 10, 2015 Date: Tuesday, February 10, 2015 12:50:29 PM Attachments: ATT00001.txt

In the News February 10, 2015

El Pais Catalonia– February 9 Gene Responsible for the Most Aggressive Prostate Cancers Discovered – Emilio de Benito Led by principal investigator Josep Domingo-Domenech, a team of researchers at The Mount Sinai Hospital in New York have found that the gene GATA2 is especially active in dangerously aggressive cancer tumors. Their work is published in Cancer Cell. The GATA2 gene is related to the differentiation and development of eukaryotes and has also been linked to lung and blood cancers. But the discovery of the gene is only part of the progress of the group. An important development has been the ability to use mice as “avatars” for cancer patients, growing tumors on the animals which then allows doctors to design a specific course of treatment for each patient. "It is truly personalized medicine," says Domingo- Domenech, since "every patient can have a mouse avatar" with exactly his cancer. - Dr. Josep Domingo-Domenech, Assistant Professor, Pathology, Icahn School of Medicine at Mount Sinai Learn more: http://cat.elpais.com/cat/2015/02/09/ciencia/1423497298_393122.html [Article is in Catalan] Additional Coverage: Prensa Libre: http://www.prensalibre.com/internacional/EEUU-Espana-cancer-salud_0_1300670028.html [Article is in Spanish]

Becker’s Hospital Review – February 9 100 hospital and health system CIOs to know | 2015 – Shannon Barnet, Emily Rappleye and Tamara Rosin This list includes CIOs and other executive-level information technology leaders from hospitals and health systems across the country. They have demonstrated excellence in leadership by tackling the challenging world of health IT and innovating during a time of change in the industry. Kumar Chatani. Executive Vice President and CIO of Mount Sinai Health System. Mr. Chatani's career as CIO of Mount Sinai Health System dates back to 2011, prior to which he served as CIO for the Northwest region of Kaiser Permanente in Portland, Ore. Under Mr. Chatani's leadership, Mount Sinai Health System won the HIMSS Enterprise Davies Award in 2012 and one of the hospitals under his direction received the HIMSS Stage 6 EMR Award. - Kumar Chatani, Chief Information Officer, Mount Sinai Health System Learn more: http://www.beckershospitalreview.com/lists/100-hospital-and-health-system-cios-to-know- 2015.html

Alzheimer’s News Today – February 9 Alzheimer’s Association Awards 5 Grants to Early-Phase Research Projects – Isaura Santos In line with its mission to aid early-phase research advancement and completion, the Alzheimer’s Association is announcing new grants to fund five early-phase clinical trials to help eliminate this gap in the research process. Tim West from C2N Diagnostics in St. Louis, Whitney Wharton at Emory University in Atlanta, Giulio Pasinetti at the Icahn School of Medicine at Mount Sinai in New York City, Russell Swerdlow at the University of Kansas Clinical Research Center in Fairway, and Stephen Cunnane, at the University of Sherbrooke in Quebec, Canada will be leading the newly awarded projects. - Dr. Giulio Pasinetti, Professor, Neurology, Psychiatry, Geriatrics and Palliative Care, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://alzheimersnewstoday.com/2015/02/09/alzheimers-association-awards-5-grants-to- early-phase-research-projects/

Time Warner Cable News – January 29 Safety Tips to Protect Children as Environment Changes – Erin Billups The common diseases affecting kids are chronic and there's growing evidence that they're a product of our changing environment. "But at the same time as we've controlled those infectious diseases, we've allowed our children to be exposed to more and more and more chemicals. Sometimes these chemicals cause acute disease, like acute lead poisoning. More often, they make children chronically sick,” said pediatrician Philip Landrigan, MD, who heads up Mount Sinai's Children's Environmental Health Center. - Dr. Philip Landrigan, Professor and System Chair, Preventative Medicine, Professor, Pediatrics, Dean for Global Health, Icahn School of Medicine at Mount Sinai, Director, Children’s Environmental Health Center at Mount Sinai Learn more: http://www.ny1.com/nyc/all-boroughs/fit-kids/2015/01/29/fit-kids-february--safety-tips-to- protect-children-as-environment-changes.html

Time Warner Cable News – January 30 Tips and Challenges to Raise Healthy Conscious Children – Erin Billups Previously, we discussed how some health experts believe environmental changes have contributed to the rise in chronic illnesses among kids. Here are some practical safety tips. If possible, avoid wall to wall carpeting which traps large amounts of mold, dust and dirt. Carpets may also include flame retardants which may be present in mattresses and couches as well. "To the extent parents can find furniture which is free of that material it's good. Those brominated flame retardants don't really do that much to retard flames, and they do a lot to damage the brains of young children,” said Philip Landrigan, MD, director of Mount Sinai Children’s Environmental Health Center. - Dr. Philip Landrigan, Professor and System Chair, Preventative Medicine, Professor, Pediatrics, Dean for Global Health, Icahn School of Medicine at Mount Sinai, Director, Children’s Environmental Health Center at Mount Sinai Learn more: http://www.ny1.com/nyc/all-boroughs/fit-kids/2015/01/30/fit-kids-february--eating-and- safety-tips-to-preview-month-of-health-challenges.html

U.S. News & World Report – February 9 HPV Vaccine Does Not Lead to Riskier Sex for Women Some Americans have long held concerns that giving teens an HPV vaccine will cause them to engage in more unprotected sex, but a new study published online by JAMA Internal Medicine shows the vaccine won't make a difference for women: They are likely to engage in sex the same way they would otherwise. Part of the reason for this is the stigma associated with the virus, which is spread through vaginal, anal and oral sex with someone who is infected. "There is a lot of fear and a lot of stigma that goes along with the HPV virus and the vaccination. This study adds to the mounting evidence that vaccination plays a different role in the sexual activity of adolescents." says Lonna Gordon, MD, clinical fellow at the Mount Sinai’s Adolescent Health Center. -Dr. Lonna Gordon, Adolescent Medicine fellow, Mount Sinai Adolescent Health Center Learn more: http://www.usnews.com/news/articles/2015/02/09/hpv-vaccine-does-not-lead-to-riskier- sex-for-women

Medpage Today – February 9 New Lung Cancer Screening Criteria Reduce False Positives – Shara Yurkiewicz New criteria developed by the American College of Radiology for lung cancer screening with low-dose computed tomography (LDCT) reduced the false-positive rate by 75% compared with previous guidelines, researchers reported. The trade-off of the new criteria -- Lung-RADS (Lung Imaging Reporting and Data System) -- was a decrease in sensitivity, according to a study published in the Annals of Internal Medicine. "The types of cancers missed were either very small ones or the so-called nonsolid cancers, which we're not even sure need to be treated at all," said David Yankelevitz, MD, a professor of radiology at the Icahn School of Medicine at Mount Sinai. - Dr. David Yankelevitz, Professor, Radiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.medpagetoday.com/Pulmonology/LungCancer/49940

Reader’s Digest – February 9 7 Silent Signs of a Heart Attack – Alyssa Jung During a heart attack, blood flow to the heart is reduced, putting extra stress on the muscle, which could make you feel exhausted, according to WebMD. Don’t be afraid to ask your doctor to do an electrocardiogram (EKG), which checks heart activity. “Sometimes when people present with lethargy, doctors won’t immediately order an EKG, which can detect a heart attack; but you should request one from your doctor, just to be safe,” says Annapoorna Kini, MD, of The Mount Sinai Hospital. -Dr. Annapoorna Kini, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.rd.com/slideshows/silent-signs-heart-attack/

Univision 41 NY– February 6 National Wear Red Day Wearing red, Johanna Contreras, MD, discussed live on Univision ways to prevent heart disease, especially in women, and the importance of raising awareness of National Go Red for Women Day. She also urged viewers to attend one of the Mount Sinai Health Systems free Community Heart Fairs held across New York City on Go Red Day, Feb. 6 from 10am-2pm, to be screened for heart disease risk factors. -Dr. Johanna Contreras, Assistant Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai Learn more: No Web Link Available

Metro Weekly– February 9 No Evidence Of Disease: Cancer Warriors Use Music As A Weapon In Their Fight – Chris Gerard For cancer patients, their families, and those entrenched in the fight to eradicate the disease and improve quality of life, music can be a powerful refuge and escape. Nobody exemplifies this more than N.E.D. (No Evidence of Disease), a band comprised of six gynecological oncologists who are warriors in the fight against women’s cancer with their both their surgical skill and their inspiring brand of rock and roll. The band includes six prominent gynecological oncologists from around the country, including Nimesh Nagarsheth, MD, of the Mount Sinai Hospital, on drums and percussion. - Dr. Nimesh Nagarsheth, Associate Professor, Obstetrics, Gynecology and Reproductive Science, Associate Director, Gynecologic Oncology, Icahn School of Medicine at Mount Sinai Learn more: http://www.metroweekly.com/2015/02/no-evidence-of-disease-cancer-warriors-use-music- as-a-weapon-in-their-fight/

LoHud.com – February 10 Know Your Cholesterol Numbers, Even If You're Young – Linda Lombroso Cholesterol used to be something that middle-aged people worried about. But with new research pointing to a connection between years of elevated cholesterol and increased risk of heart disease later in life, it's important to be aware of your numbers, even when you're young. A lipid profile — a blood test done after fasting — will provide your total cholesterol, as well as other critical numbers: LDL ("bad" cholesterol), HDL ("good" cholesterol) and triglycerides, said Alon Gitig, MD, a cardiologist with Mount Sinai Riverside Medical Group in Yonkers. - Dr. Alon Gitig, Assistant Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.lohud.com/story/news/health/2015/02/10/know-cholesterol-numbers/23163113/

Yoga Journal – February 6 Master the Sugar-Free Diet (and Avoid the Energy Crash) – Kerri-Ann Jennings Turns out, eliminating sugar isn’t as simple as cutting out cake, cookies, and other sweet treats. “Many people tell me they don’t eat sugar, but they don’t realize there are so many foods that contain sugar, including some that seem healthy,” says Nicole Avena, PhD, assistant professor of pharmacology at Icahn School of Medicine at Mount Sinai and co-author of Why Diets Fail. - Nicole Avena, PhD, Assistant Professor, Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai Learn more: http://www.yogajournal.com/article/food-diet/sugar-free-diet-without-crash/

Domain-B.com – February 9 Now, Smart Phones to Diagnose HIV and Syphilis Engineers have created a compact, handheld device that plugs into an iPhone and turns it into a mobile laboratory that could diagnose HIV and syphilis in 15 minutes flat, www.latimes.com reported. Meanwhile, www.nydailynews.com reported that Antonio Urbina, MD, the medical director of The Mount Sinai Hospital's Institute for Advanced Medicine who was not involved in the project as saying it was a game-changer in terms of the (home) diagnostics consumers could do. - Dr. Antonio Urbina, Senior Faculty, Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai, Medical Director, The Mount Sinai Hospital’s Institute for Advanced Medicine Learn more: http://www.domain-b.com/technology/Health_Medicine/20150209_syphilis.html

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of MountSinaiNewsNow Subject: Mount Sinai In The News - February 9, 2015 Date: Monday, February 09, 2015 12:14:28 PM Attachments: ATT00001.txt

In the News February 9, 2015

Crain’s New York – February 9 Mount Sinai Type 1 Diabetes Trial A 10-patient trial at the Icahn School of Medicine at Mount Sinai is testing an artificial pancreas system that has the potential to reduce the burden of diabetes management on the 3 million Americans with type 1 diabetes. Mount Sinai is one of three sites studying the device, developed at the University of Virginia. The system, specially designed for each patient, uses a glucose sensor, smartphone application and insulin pump to read patients’ blood-sugar levels while they sleep and administers an appropriate amount of insulin. The device could become publicly available in three to five years, pending FDA approval, said Carol Levy, MD, the study’s principal investigator at Mount Sinai. - Dr. Carol Levy, Associate Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://www.crainsnewyork.com/article/20150209/PULSE/150209852/nyu-langone-addresses- deficiencies# [Login Required]

Psych Central – February 9 Cocaine Users Have a Hard Time Predicting Loss – Traci Pedersen In people with a cocaine addiction, brain circuits responsible for predicting emotional loss become impaired, according to new research conducted at the Icahn School of Medicine at Mount Sinai in New York. That is one reason why many continue to use the drug even after facing devastating consequences such as imprisonment or the loss of a relationship. “We found that people who were addicted to cocaine have impaired loss prediction signaling in the brain,” said Muhammad Parvaz, PhD, lead author of the study. “This is the first time a study has targeted the prediction of both gains and losses in drug addiction, showing that deficits in prediction error signaling in cocaine addicted individuals are modulated by recent cocaine use,” said principal investigator Rita Goldstein, PhD, professor of psychiatry and neuroscience. - Muhammad Parvaz, PhD, Assistant Professor, Psychiatry, Icahn School of Medicine at Mount Sinai -Rita Goldstein, PhD, Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://psychcentral.com/news/2015/02/09/cocaine-users-have-a-hard-time-predicting- loss/80987.html

The Daily Beast via the Daily Burn – February 6 The Breakfast That Could Help You Eat 50 Percent Less at Lunch – Amanda Woerner In the latest science-backed battle of the breakfast foods, researchers from the New York Nutrition Obesity Research Center at St. Luke’s Hospital in New York City tested whether a breakfast of corn flakes or oatmeal would help people feel more satiated. “We tried to make [the breakfasts] as similar as possible by adding a certain amount of milk to the corn flakes, but they weren’t exactly the same,” says study author Allan Geliebter, PhD, research psychologist in the Department of Psychiatry at Mount Sinai St. Luke’s Hospital. - Allan Geliebter, PhD, Assistant Clinical Professor, Icahn School of Medicine at Mount Sinai Learn more: http://www.thedailybeast.com/articles/2015/02/06/the-breakfast-that-could-help-you-eat- 50-percent-less-at-lunch.html

Care2.com – February 8 Are Dogs Becoming Doctors for Cancer Patients? – Lisa Spector An average dog can understand over 150 words, and some Border Collies have proven to know upwards of 200 words. While that is amazing, dogs still haven’t yet learned how to get into medical school. But, maybe they don’t need to in order to help treat cancer patients. Author and psychology professor Stanely Coren wrote about the research headed by Stewart Fleishman, founding director of Cancer Supportive Services at Mount Sinai Beth Israel in New York City. The study wanted to measure the effect therapy dogs had on helping very ill cancer patients undergoing painful radiation and chemotherapy treatment. Gabriel A. Sara, medical director at Mount Sinai Roosevelt reported to The Daily Record, “The study provides strong evidence that pet therapy can be used as an effective tool for patients.” - Dr. Stewart Fleishman, Founding Director, Cancer Supportive Services, Mount Sinai Beth Israel - Dr. Gabriel Sara, Assistant Clinical Professor, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, Medical Director, Mount Sinai Roosevelt Learn more: http://www.care2.com/greenliving/are-dogs-becoming-doctors-for-cancer-patients.html

The New York Times – February 7 The Dangers of Vaccine Denial – Nicholas Kristof In reporting on poverty worldwide, I’ve seen how much vaccines improve human well-being. I understand how troglodytes in the Taliban or Boko Haram can be suspicious of vaccines, but politicians here in affluent, well-educated America? Moms and dads in Santa Monica? Philip J. Landrigan, MD, the chairman of the department of preventative medicine at the Icahn School of Medicine at Mount Sinai, says that there may be environmental factors linked to autism, but these relate to endocrine disrupting chemicals in consumer products, not to vaccines. - Dr. Philip Landrigan, Professor and System Chair, Preventative Medicine, Professor, Pediatrics, Dean for Global Health, Icahn School of Medicine at Mount Sinai Learn more: http://www.nytimes.com/2015/02/08/opinion/sunday/nicholas-kristof-the-dangers-of- vaccine-denial.html?_r=0

Forbes – February 8 NED, A Vibrant Band of Doctors Rocking For Women with Cancer – Elaine Schattner N.E.D. is a doctor’s old shorthand for remission. It’s also the name of a rock band that’s breaking the silence surrounding gynecological cancers, conditions that some women still hesitate to mention: cancer of the cervix, ovary, uterus, vagina and vulva. The band started in 2008 when a group of six physicians performed at the annual meeting of the Society of Gynecologic Oncology in Tampa, Florida. “We got together in a hotel room, and then we played for the society,” recalls Nimesh Nagarsheth, MD, the drummer. He currently practices at The Mount Sinai Hospital in Manhattan and Englewood Hospital in New Jersey. - Dr. Nimesh Nagarsheth, Associate Professor, Obstetrics, Gynecology and Reproductive Science, Associate Director, Gynecologic Oncology, Icahn School of Medicine at Mount Sinai Learn more: http://www.forbes.com/sites/elaineschattner/2015/02/08/ned-a-rock-band-of-gynecological- oncology-doctors-make-music-for-womens-cancers-in-music-and-film/

NBC Nightly News – February 7 Hard Hits – Ron Mott It’s an issue that’s already cast a shadow over the NFL, brain damage suffered by some players as a result of repeated hard hits. But now a landmark lawsuit is putting youth football in the spotlight. While not involved with this case, Melissa Leber, MD, has been treating young athletes for years. “I think parents’ concerns are warranted. They make sense. And their fears are heard,” she says. - Dr. Melissa Leber, Assistant Professor, Orthopaedics, Icahn School of Medicine at Mount Sinai Learn more: http://www.nbcnews.com/nightly-news/video/nightly-news-with-lester-holt-full- broadcast-february-7-395806275567

Women’s Health – February 6 Why You Keep Getting a Pimple in the SAME Exact Spot – Ashley Oerman Can you predict the location of your next zit as accurately as the date of your next period? If you said yes, we feel your pain. Luckily, there are steps you can take to end the vicious cycle of super stubborn, frustrating pimples, says Joshua Zeichner, MD, director of cosmetic and clinical research in dermatology at The Mount Sinai Hospital in New York City. Here's what you need to know about this aggravating type of acne—and how to banish it for good. - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://edit.womenshealthmag.com/beauty/getting-acne-in-the-same-place

The New York Daily News – February 6 Swing Guru and Doctors Question Tiger Woods’ Future – Hank Gola Outside of his personal life, nothing much is going right for Tiger Woods. How’s that for a change? Those dreaded back spasms returned to force another withdrawal from the Farmers Insurance Open on Thursday, leaving his future open to speculation. Never before has it been this much in doubt. “It’s a game that requires tremendous amounts of swing velocity. The forces on the spine from violent twisting motion are extraordinary,” said Andrew Hecht, MD, Chief of Spine Surgery and Director of the Spine Center at The Mount Sinai Hospital in New York. -Dr. Andrew Hecht, Associate Professor, Orthopaedics, Neurosurgery, Icahn School of Medicine at Mount Sinai, Director, the Spine Center at Mount Sinai Learn more: http://www.nydailynews.com/sports/more-sports/swing-guru-doctors-question-tiger- woods-future-article-1.2106475

Teen Vogue – February 6 Ouch! How to Cure a Curling Iron Burn– Emily Gaynor The other day I was curling my hair and I smacked the device right into my forehead. After the shock of a 350-degree metal rod coming into contact with my skin subsided, I looked in the mirror and realized I really had hurt myself. Turns out, you really aren't supposed to waste much time when it comes to a burn. I spoke with Jeannette Graf, MD, Assistant Clinical Professor of Dermatology at The Mount Sinai Hospital and Heidi Waldorf, MD, Director of Laser and Cosmetic Dermatology at The Mount Sinai Hospital, to flesh out a full-proof plan for dealing with hair tool trauma. - Dr. Jeannette Graf, Assistant Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai - Dr. Heidi Waldorf, Associate Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Laser and Cosmetic Dermatology, The Mount Sinai Hospital Learn more: http://www.teenvogue.com/beauty/skin-care/2015-01/curling-iron-burn-treatment Additional Coverage: Yahoo Beauty: https://www.yahoo.com/beauty/ouch-how-to-cure-a-curling-iron-burn- 109605742785.html

The New York Daily News – February 6 Turning Red for Heart Health Neighbors in Harlem learn how to care for their hearts in honor of February, "American Heart Month,” at The Mount Sinai Hospital. 56% of women a year die of heart disease. The rate of death from heart disease is higher than that of breast cancer. To bring awareness to the serious dangers posed by heart disease, Mount Sinai Heart at The Mount Sinai Hospital hosted the “Go Red” event that included blood pressure tests and healthy cooking demonstrations. -Eileen Hughes, NP, Nursing Director, Mount Sinai Heart at The Mount Sinai Hospital -Matthew Krimsky, Senior Executive Chef of Food and Nutrition Services, The Mount Sinai Hospital Learn more: http://video.nydailynews.com/Turning-Red-for-Heart-Health-28511187?playlistId=10623

Doctors Lounge via Healthday – February 5 IUDs, Contraceptive Implants Work Longer Than Thought, Researchers Report – Robert Preidt Hormonal intrauterine devices (IUDs) and contraceptive implants appear to prevent pregnancy one year beyond their approved length of use, according to early results from an ongoing study. An expert pointed out another plus to IUDs and implants. "All methods mentioned have the additional benefit of minimizing menstrual bleeding," said Taraneh Shirazian, MD, an assistant professor of obstetrics, gynecology and reproductive science at the Icahn School of Medicine at Mount Sinai, in New York City. - Dr. Taraneh Shirazian, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://www.doctorslounge.com/index.php/news/hd/52872

Yahoo Health via Elle – February 8 Can This New Miracle Product Reverse The Effects Of Sun Damage? – April Long Imagine this: a substance that, when smoothed over sun-damaged skin, reverses the effects of UV exposure, potentially preventing the development of skin cancer as well as nixing the signs of UV- related aging before they even begin. "I always tell my patients that when it comes to sun damage, you can't undo what's been done," says Joshua Zeichner, MD, an assistant professor of dermatology at the Mount Sinai Hospital. “Now, for the first time, there may be ingredients that truly turn back the hands of time." - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: https://www.yahoo.com/health/can-this-new-miracle-product-reverse-the-effects- 109891956408.html

Tech Times – February 9 Now Your Smartphone Can Tell You If You Have HIV or Syphilis (And It's Darn Accurate, Too) – Rhodi Lee Smartphones can do a lot of things from waking you up in the morning to tracking your fitness activities. Now a group of engineers has made the device a lot smarter. The team from Columbia University has come up with a compact and handheld device that when plugged into the iPhone can turn it into a portable laboratory that can be used to diagnose sexually transmitted diseases, syphilis and HIV in as short as 15 minutes using finger prick of a person's blood. Antonio Urbina, from The Mount Sinai Hospital's Institute for Advanced Medicine, said that other self-tests for HIV are delivered to laboratories or use oral fluid costing as much as $20,000. - Dr. Antonio Urbina, Senior Faculty, Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai, Medical Director, The Mount Sinai Hospital’s Institute for Advanced Medicine Learn more: http://www.techtimes.com/articles/31703/20150209/now-your-smartphone-can-tell-you-if- you-have-hiv-or-syphilis-and-its-darn-accurate-too.htm Additional Coverage: STARR FM: http://www.starrfmonline.com/1.1986378 Diabetes Insider: http://diabetesinsider.com/columbia-university-study-reveals-new-mobile-device- dongle-can-diagnose-stds/37805 SMN Weekly: http://www.smnweekly.com/a-smartphone-that-can-diagnose-hiv-and-other- illness/14207/

Time Warner Cable News – February 8 Fit Kids: Dealing with Day-to-Day Health Issues – Jill Urban Being a parent comes with a lot of worry. Whether it is a fever, a rash or a sore throat, many parents, especially new parents need guidance when it comes to dealing with day-to-day health issues. We asked pediatrician Erica Brody, MD, to highlight some common mistakes she sees parents make and to offer some tips. - Dr. Erica Brody, Assistant Professor, Pediatrics, Pediatrics Associates, Icahn School of Medicine at Mount Sinai, Director, Pediatric Breastfeeding Medicine, Kravis Children’s Hospital at The Mount Sinai Hospital Learn more: http://www.ny1.com/nyc/all-boroughs/fit-kids/2015/02/5/fit-kids--dealing-with-day-to- day-health-issues.html

BrainFacts.org – February 3 Sweet Talk: The Brain and Sugar – Jessica P. Johnson We’ve all felt that burst of sudden energy that comes after eating a candy bar. But have you ever wondered why we often crave sugary foods even when we’re not particularly hungry? And why does sugar have such a different effect on our brains than, say, a plate of lima beans? On average, the typical American consumes 22 teaspoons of added sugar each day and this is much greater than what the World Health Organization recommends. And you have to keep in mind this is added sugar that’s put on top of the sugar that’s naturally occurring in foods. - Nicole Avena, PhD, Assistant Professor, Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai Learn more: http://www.brainfacts.org/across-the-lifespan/diet-and-exercise/articles/2015/sweet-talk- the-brain-and-sugar/

News-Medical – February 9 NYEE Ophthalmologists Offer Prevention Tips to Observe AMD Awareness Month Macular degeneration is a major cause of irreversible vision loss in the United States and around the world. As many as 11 million Americans have some form of macular degeneration. To observe Age- Related Macular Degeneration (AMD) Awareness Month, ophthalmologists at New York Eye and Ear Infirmary of Mount Sinai (NYEE) and the Mount Sinai Health System are offering prevention tips and raising awareness of options for early detection and effective treatment. -Dr. Robin N. Ginsburg, Assistant Professor, Ophthalmology, Icahn School of Medicine at Mount Sinai, Director of the Vitreoretinal Service, The Mount Sinai Hospital -Dr. Richard B. Rosen, Professor, Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, Surgeon Director, Retina Service Chief, and Director of Ophthalmology Research, New York Eye and Ear Infirmary Learn more: http://www.news-medical.net/news/20150209/NYEE-ophthalmologists-offer-prevention- tips-to-observe-AMD-Awareness-Month.aspx

The New York Daily News – February 8 February Is American Heart Month, a Good Time to Consider What You Can Do to Stay Heart- Healthy – Katie Charles The drugstores are brimming with heart-shaped chocolate boxes, but February is also American Heart Month — a good time for stepping back to assess what you can do to keep your heart healthy. “Cardiovascular disease is a term for diseases of the heart as well as of the arteries and veins that supply the organs with blood,” says The Director of Mount Sinai Heart, Valentin Fuster, MD. “Overall, cardiovascular disease is an acquired disease that results from factors like high blood pressure and cigarette smoking — which means that it’s also largely preventable.” - Dr. Valentin Fuster, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Heart, the Zena and Michael A. Wiener Cardiovascular Institute, the Marie-Josée and Henry R. Kravis Center for Cardiovascular Health Learn more: http://www.nydailynews.com/life-style/health/february-american-heart-month-article- 1.2100765

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 6, 2015 Date: Friday, February 06, 2015 12:18:22 PM Attachments: ATT00001.txt

In the News February 6, 2015

Medpage Today – February 5 FDA Boss Hamburg Stepping Down – Joyce Frieden FDA commissioner Margaret Hamburg, MD, is leaving the agency. “It is with very mixed emotions that I write today to inform you that I plan to step down as FDA Commissioner at the end of March 2015,” Hamburg wrote in a letter to employees, which was posted Thursday on the FDA’s website. Kenneth Davis, MD, president and CEO of the Mount Sinai Health System in New York City noted that although there are a number of good candidates to replace Hamburg, “That is not the question. The problem is that the FDA is under-resourced for the job it needs to do.” - Dr. Kenneth L. Davis, CEO and President, Mount Sinai Health System Learn more: http://www.medpagetoday.com/Washington-Watch/FDAGeneral/49887

CNBC – February 5 Cocaine Makes Brains Worse at Learning from Mistakes – Robert Ferris Cocaine addicts may have more difficulty recognizing the effects of bad decisions, because the drug may actually impair the circuits in the brain responsible for recognizing and predicting loss, according to a new study. "The human species is guided by the prospect of maximizing rewards and minimizing costs," said Rita Goldstein, one of the scientists on the research team. "When you are taking the drug again, you are getting that high, and you are getting those positive responses, but you are not getting the ability to predict the negative ones," said Muhammad Parvaz, a researcher involved with the study. - Muhammad Parvaz, PhD, Assistant Professor, Psychiatry, Icahn School of Medicine at Mount Sinai -Rita Goldstein, PhD, Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://www.cnbc.com/id/102397769 Additional Coverage: NBC News: http://www.nbcnews.com/business/business-news/another-reason-wall-streeters-avoid-cocaine-n301466 Clandestinoweb: http://www.clandestinoweb.com/number-news/168736-perche-chi-si-fa-di-coca-non-riesce-a-smettere-lo-rivela-lo-studio-della-mount-sinai- school-of-medicine-di-new-york/ [Article is in Italian]

Medscape – January 19 Depression: Allergic Reaction? Infectious Disease? – Pauline Anderson Researchers are exploring exciting lines of evidence suggesting that depression is not simply an imbalance of neurochemicals in the brain but possibly fallout from an inflammatory response mounted by the body to deal with stress. Investigators at the Icahn School of Medicine at Mount Sinai, in New York City, recently linked differences in the peripheral immune system in a mouse model to susceptibility to social stress, findings they correlated with serum cytokine levels in patients with treatment-resistant depression. - Scott Russo, PhD, Associate Professor, Neuroscience, Icahn School of Medicine at Mount Sinai -Georgia Hodes, PhD, Postdoctoral Fellow, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/838376 [Login required]

Oncology Nurse Advisor – February 6 Close Monitoring of Renal Tumors May Provide Alternative to Surgery – Kathy Boltz, PhD In patients with small renal tumors confined to the kidneys, close, active monitoring, as opposed to immediate surgery, is associated with low rates of tumor growth or death, according to a study published in the Journal of Urology (2014; doi:10.1016/j.juro.2014.03.038). "We are beginning to better understand the behavior of tumors that grow on the kidneys," said the study's lead investigator, Reza Mehrazin, MD, assistant professor of Urology at the Icahn School of Medicine at Mount Sinai in New York, New York. "In some patients, particularly those who are considered elderly or 'high risk,' we are now more likely able to delay surgery, sometimes indefinitely." - Dr. Reza Mehrazin, Assistant Professor, Urology, Icahn School of Medicine at Mount Sinai Learn more: http://www.oncologynurseadvisor.com/close-monitoring-of-renal-tumors-may-provide-alternative-to-surgery/article/396582/

Science Now – February 5 Shattered Chromosome Cures Woman of Immune Disease – Jocelyn Kaiser A girl who grew up with a serious genetic immune disease was apparently cured in her 30s by one of her chromosomes shattering into pieces and reassembling. The woman suffered from recurring bacterial infections as a child. Doctors found that she had abnormally low levels of certain white blood cells needed to fight invading microbes. The 9-year-old’s illness, described in two reports in 1964 in The New England Journal of Medicine, was the first known case of what is now called WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. “Very interesting,” says clinical geneticist George Diaz of the Icahn School of Medicine at Mount Sinai in New York City, who identified CXCR4 mutations as the cause of WHIM. - Dr. George Diaz, Associate Professor, Genetic and Genomic Sciences, Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: http://news.sciencemag.org/biology/2015/02/shattered-chromosome-cures-woman-immune-disease

Healthday – February 5 IUDs, Contraceptive Implants Work Longer Than Thought, Researchers Report – Robert Preidt Hormonal intrauterine devices (IUDs) and contraceptive implants appear to prevent pregnancy one year beyond their approved length of use, according to early results from an ongoing study. An expert pointed out another plus to IUDs and implants. "All methods mentioned have the additional benefit of minimizing menstrual bleeding," said Taraneh Shirazian, MD, an assistant professor of obstetrics, gynecology and reproductive science at the Icahn School of Medicine at Mount Sinai, in New York City. - Dr. Taraneh Shirazian, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/women-s-health-information-34/birth-control-news-62/early-results-show-iuds-contraceptive-implants-work- longer-than-thought-696194.html Additional Coverage: Health.com: http://news.health.com/2015/02/06/iuds-contraceptive-implants-work-longer-than-thought-researchers-report/ Philly.com: http://www.philly.com/philly/health/topics/HealthDay696194_20150205_IUDs__Contraceptive_Implants_Work_Longer_Than_Thought__Researchers_Report.html

Healthday – February 6 5 Babies at Illinois Day Center Diagnosed With Measles – Dennis Thompson Illinois health officials said five babies who attend a suburban Chicago day care center have come down with the highly infectious childhood disease. Many parents aren't getting their children vaccinated against measles, due largely to what experts call mistaken fears about childhood vaccines. A big contributing factor to the parents' concerns about vaccine safety was a 1998 paper published and later retracted in the medical journal The Lancet. Michael Tosi, MD, chief of pediatric infectious diseases at the Kravis Children's Hospital at Mount Sinai in New York City, said, "Any concerns or claims about a connection between measles vaccine and autism in young children have absolutely no scientific basis and have been entirely discredited." - Dr. Michael Tosi, Clinical Professor, Pediatrics, Infectious Diseases, Icahn School of Medicine at Mount Sinai, Chief of Pediatric Infectious Diseases, Kravis Children’s Hospital at Mount Sinai Learn more: http://consumer.healthday.com/public-health-information-30/centers-for-disease-control-news-120/u-s-measles-cases-now-exceed-100-cdc- 696257.html Additional Coverage: Physicians News Digest: http://www.physiciansnews.com/2015/02/06/5-babies-at-illinois-day-center-diagnosed-with-measles/

Economia Digital – February 5 Valentin Fuster Says That Altruism Improves Health The cardiologist Valentin Fuster considers the motivation of people is essential for their health care. One of the aspects that encourage this is altruism, which in his opinion should replace the current consumerism. Fuster, medical director of Mount Sinai Cardiovascular Institute in New York (USA), stresses the need to improve the overall health of the population and the importance of not only prevention but, above all, the promotion of health. - Dr. Valentin Fuster, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Heart, the Zena and Michael A. Wiener Cardiovascular Institute, the Marie-Josée and Henry R. Kravis Center for Cardiovascular Health Learn more: http://www.economiadigital.es/es/notices/2015/02/el-altruimso-65924.php [Article is in Spanish] Additional Coverage: Infosalus: http://www.infosalus.com/actualidad/noticia-valenti-fuster-ve-estudio-conexion-cerebro-corazon-reto-decada-20150206135320.html [Article is in Spanish] Lainformacion.com: http://noticias.lainformacion.com/salud/obesidad/valenti-fuster-ve-en-el-estudio-de-la-conexion-cerebro-y-corazon-el-reto-de-la- decada_5wUBVtPlNsquuO1bTCMPU1/ [Article is in Spanish]

Fit Pregnancy – February/March 2015 Health Check: Is It Safe to…? – Emily C. Johnson and Paige Fowler Is it safe to do hot yoga? Practicing prenatal yoga can keep you calm, decrease back pain and strengthen muscles, but save the heat for after baby’s arrival. “I wouldn’t recommend hot yoga during pregnancy, especially in the first trimester,” says Joanna Stone, MD, director of Maternal Fetal Medicine at The Mount Sinai Hospital in New York City. “Exercising in high temperatures between five and six weeks, when the neural tube is closing, is associated with increased risk of birth defects.” And once you move past this marker, the pools of sweat you acquire in class can lead to dehydration. - Dr. Joanne Stone, Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Director, Maternal Fetal Medicine, The Mount Sinai Hospital Learn more: No Web Link Available

Time Warner Cable News – February 5 Fit Kids: Dealing with Day-to-Day Health Issues – Jill Urban Being a parent comes with a lot of worry. Whether it is a fever, a rash or a sore throat, many parents, especially new parents need guidance when it comes to dealing with day-to-day health issues. We asked pediatrician Erica Brody, MD, to highlight some common mistakes she sees parents make and to offer some tips. - Dr. Erica Brody, Assistant Professor, Pediatrics, Pediatrics Associates, Icahn School of Medicine at Mount Sinai, Director, Pediatric Breastfeeding Medicine, Kravis Children’s Hospital at the Mount Sinai Hospital Learn more: http://www.ny1.com/nyc/all-boroughs/fit-kids/2015/02/5/fit-kids--dealing-with-day-to-day-health-issues.html

WHYY – February 5 Sugar: Health's Latest Public Enemy – Audrey Quinn About 15 years ago, Nicole Avena, a neuroscientist at Mount Sinai School of Medicine in New York, noticed a lot of people talking about how they felt "addicted" to sugar. "There really wasn't any scientific evidence," she says. "There wasn't any carefully controlled or conducted studies on this." So, she joined a team that was starting a study—in rats, to begin with. The sugar-hooked rats' brains looked like drug addicts' brains. So in the past few years she's been working with human subjects, and finding similar things. People who show addiction-like behaviors towards sugar also show drug-addiction-like changes in their brain. - Nicole Avena, PhD, Assistant Professor, Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai Learn more: http://www.newsworks.org/index.php/local/the-pulse/78009-sugar-healths-latest-public-enemy-

LoHud.com – February 5 'Could Have Been Me': Last-Minute Choices Haunt Commuters – Karen Croke Call it a twist of fate. On Tuesday, Bruce Cohen, a Manhattan real estate lawyer, decided to do a favor for a friend and wasn't in his usual seat on the 5:44 p.m. Metro-North train out of Grand Central to his home in Mount Kisco. Conversely, Chris Gross was on the 5:44 p.m. that day instead of his usual train. He'd stopped to buy sneakers after work and missed the previous train. Gross ended up with a seat in the first car. The random nature of tragedy affects everyone, says Harris Stratyner, a clinical associate professor of psychiatry at Icahn School of Medicine at Mount Sinai, whether as victims or those — like Cohen — who manage to avoid a catastrophe for reasons they just don't understand. - Dr. Harris Stratyner, Associate Clinical Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.lohud.com/story/news/transit/2015/02/05/valhalla-crash-last-minute-choices-change-destinies/22951377/

Information Television Network – February 5 Learning About Primary Immunodeficiency Infections caused by organisms such as bacteria, viruses or fungi are a normal part of life. However, a pattern of frequent and recurring infections is not - such as pneumonia, bronchitis, sinus infections, ear infections, meningitis or skin and blood infections. The reason for these frequent occurrences may be a condition known as, primary immunodeficiency. The result can be a compromised immune system which can be serious. One of the best known experts on this topic is Charlotte Cunningham-Rundles, MD. - Dr. Charlotte Cunningham-Rundles, Professor, Medicine, Pediatrics, David S. Gottesman Professor of Immunology, Icahn School of Medicine at Mount Sinai Learn more: http://www.itvisus.com/programs/hbhm/episode_3205.asp

The Philadelphia Tribune – February 5 Observance raises awareness of HIV in the Black community – Ayana Jones The Real Impact Project, also known as TRIP, marked National Black HIV/AIDS Awareness Day (NBHAAD) with an event titled “Red Matters” on Thursday at the Tabu Lounge. The event celebrated the African-American men and women who maintain resilience while living with HIV. Featuring guest included Louis Farmer, an HIV-positive activist, health educator and LBGT mentor who works as care coordinator of the HIV clinic at N.Y.C.’s Mount Sinai Beth Israel. - Louis Farmer, HIV Care Coordinator, Mount Sinai Beth Israel Learn more: http://www.phillytrib.com/news/observance-raises-awareness-of-hiv-in-the-black-community/article_aa9516e7-1f6b-5819-a769- 0b562e02c02b.html

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 5, 2015 Date: Thursday, February 05, 2015 12:54:26 PM Attachments: ATT00001.txt

In the News February 5, 2015

Medscape – February 5 Impaired Reward Processing May Explain Cocaine Addiction – Pam Harrison Impairments in reward processing decisions may help explain why addicted individuals go back to abusing cocaine despite the often terrible consequences of addiction, new research suggests. "We know from reward-related studies, especially from preclinical studies, that there is an impairment in reward prediction error signals in addicted brains," Muhammad Parvaz, PhD, assistant professor of psychiatry, Icahn School of Medicine at Mount Sinai, New York City, told Medscape Medical News. - Muhammad Parvaz, PhD, Assistant Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/839298 Additional Coverage: The Times of India: http://timesofindia.indiatimes.com/life-style/health-fitness/health/Cocaine-use- impairs-loss-prediction-ability/articleshow/46129945.cms The Courier-Journal: http://www.courier-journal.com/story/tech/science/2015/02/04/bad-habits-cocaine- addicts/22875495/ Thomasville Times-Enterprise: http://www.timesenterprise.com/news/why-cocaine-addicts-keep- making-bad-decisions/article_e7bf6cd4-ac84-11e4-9676-8b392779cb06.html Giornale di Sicilia: http://gds.it/2015/02/05/difficile-smettere-di-assumere-cocaina-uno-studio-spiega- perche_307705/ [Article is in Italian]

Medical Daily – February 3 Cocaine Effects Include Harm Done To Brain Circuits That Predict Loss – Susan Scutti Our ability to learn from our experiences shapes our lives. A new study explores how addiction influences this crucial ability. People addicted to cocaine, say researchers at Icahn School of Medicine at Mount Sinai, continue their habit despite horrible consequences, such as losing a job, because the circuits in their brain responsible for predicting emotional loss have been harmed by drug use. - Muhammad Parvaz, PhD, Assistant Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.medicaldaily.com/cocaine-effects-include-harm-done-brain-circuits-predict- loss-320614

Straight.com – February 4 Therapy Dogs Improve Patient Well-Being Therapy dogs are being used in a hospice program at the University of British Columbia (UBC). A UBC professor emeritus pointed to a January study about cancer patients at Mount Sinai Beth Israel that showed that on the day of visitation by therapy dogs, patients requested less painkilling medication and seemed to be more motivated to continue with their treatments. -Mount Sinai Beth Israel Learn more: http://www.straight.com/life/818971/therapy-dog-visits-alleviate-stress-improve-well- being

Medical Xpress – February 5 Study Links New Genetic Anomalies to Breast Cancer in African American Families – Patricia Donovan The "Jewels in our Genes" study, led by University at Buffalo researcher Heather Ochs-Balcom, has uncovered previously unknown segments of DNA shared by African American family members who have breast cancer. It was conducted between 2009 and 2014 by researchers in the UB School of Public Health and Health Professions, Case Western Reserve School of Medicine, Roswell Park Cancer Institute and the Icahn School of Medicine at Mount Sinai Hospital, New York. -Icahn School of Medicine at Mount Sinai Learn more: http://medicalxpress.com/news/2015-02-links-genetic-anomalies-breast-cancer.html

Hindustan Times – February 4 Say No To Roasted or Fried Food to Keep Alzheimer's Away Eating roasted or fried meat could increase the risk of Alzheimer's disease, a new study suggests. The research provides evidence that cooking foods at high temperatures increases the risk of Alzheimer's disease. "This epidemiological study supports our previous findings in animals and humans of an important role for dietary AGEs in Alzheimer's disease," Jaime Uribarri, MD, and Weijing Cai of The Icahn School of Medicine, said. -Dr. Jaime Uribarri, Professor, Medicine, Nephrology, Icahn School of Medicine at Mount Sinai -Weijing Cai, PhD, Senior Scientist, Geriatrics and Palliative Care, Icahn School of Medicine at Mount Sinai Learn more: http://www.hindustantimes.com/wellness/say-no-to-roasted-or-fried-food-to-keep- alzheimer-s-away/article1-1313938.aspx Additional Coverage: Khaleej Times: http://www.khaleejtimes.com/kt-article-display-1.asp? section=food&xfile=data/food/2015/February/food_February4.xml Newsmax: http://www.newsmax.com/fastfeatures/arthritis-pain-foods-health/2015/02/04/id/622642/

El Nuevo Dia – February 5 FDA Approves Drug to Treat Parkinson’s The Federal Food and Drug Administration (FDA) approved Duopa ™ of AbbVie for the treatment of motor fluctuations for people with advanced Parkinson's disease. Duopa is administered using a portable infusion pump, which provides carbidopa and levodopa directly to the small intestine for 16 continuous hours through a tube placed during a procedure. "There is a need, still unsatisfied, for treatment options for patients with advanced Parkinson's disease. As the disease progresses, it may be difficult to control the motor features, "said C. Warren Olanow, MD, Professor of Neurology and Neuroscience at the Icahn School of Medicine at Mount Sinai and principal investigator of the Duopa trial. - Dr. C. Warren Olanow, Henry P. and Georgette Goldschmidt Professor of Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://www.elnuevodia.com/ciencia/ciencia/nota/fdaapruebamedicamentoparatratarelparkinson- 2003870/ [Article is in Spanish]

USA Today – February 4 Rocking Doctors Make Noise about Below-The-Belt Cancers – Kim Painter There are fewer than 1,000 gynecologic oncologists in the United States, and they generally are busy treating women with cancers of the reproductive tract. So it may be surprising that six of them, scattered from Alaska to North Carolina, managed to form a rock band good enough to get two albums released and to get gigs outside the fundraising circuit. Members of the band include drummer Nimesh Nagarsheth of The Mount Sinai Hospital, New York City. - Dr. Nimesh Nagarsheth, Associate Professor, Obstetrics, Gynecology and Reproductive Science, Associate Director, Gynecologic Oncology, Icahn School of Medicine at Mount Sinai Learn more: http://www.usatoday.com/story/news/2015/02/04/rock-band-doctors-cancer/22810531/

Medscape – February 4 Tonight: Oncologists' Rock Band in 'Raw, Emotional Film' – Nick Mulcahy A documentary about six gynecologic (GYN) oncologists and their rock band and patients will screen tonight in more than 40 American cities in honor of World Cancer Day. The film, No Evidence of Disease, which is also the name of the band, tells the stories of a collection of patients with GYN cancers, their families, and the six doctors. The documentary has won multiple awards and was described as a "raw, emotional" film that brings "statistics to life" by US News and World Report. The band includes Nimesh Nagarsheth of The Mount Sinai Hospital. - Dr. Nimesh Nagarsheth, Associate Professor, Obstetrics, Gynecology and Reproductive Science, Associate Director, Gynecologic Oncology, Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/839190

Healthday – February 4 Imaging Tests May Help Stem Amputations for Circulatory Disorder – Steven Reinberg Patients with peripheral arterial disease (PAD) who face amputation of a foot or leg can have their limb saved by minimally invasive surgery to improve blood flow, a new study suggests. Gerald Bernstein, MD, is director of the diabetes management program at Mount Sinai Beth Israel Medical Center in New York City. He said, "We have learned that, in the world of diabetes, the simple act of having patients remove their shoes and socks allows for an examination of the peripheral pulses in the feet as well as the quality and health of the skin." -Dr. Gerald Bernstein, Associate Clinical Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/health-technology-information-18/imaging-device-health- news-401/imaging-tests-can-help-stem-amputations-for-circulatory-disorder-696148.html Additional Coverage: Doctors Lounge: http://www.doctorslounge.com/index.php/news/hd/52821

Western Queens Gazette – February 4 Constantinides Delivers State Of District – Richard Gentilviso In his first State of the District address on January 29, Councilmember Costa Constantinides spoke of current successes and future visions. In the newly renovated P.S. 151 auditorium in Woodside within District 22, Constantinides noted, “This past year we secured funding for community health, open space, and education.” In health, $2.1 million went for a PET scan at Mount Sinai Queens. -Mount Sinai Queens Learn more: http://www.qgazette.com/news/2015-02- 04/Features/Constantinides_Delivers_State_Of_District.html

MaineNewsOnline.com – February 4 Younger Diabetic patients lacking Medical Care: Study – Tanya Campbell According to the Centers for Disease Control and Prevention (CDC), all the young people suffering from diabetes are largely lacking access to medical care as compared to the older people who suffer from the disease. The CDC report has stated that there are about 19% of young American adults who are aged between 18 and 39 years and have diabetes yet they have not visited a medical professional in the last six months. Gerald Bernstein, MD, Director of the Diabetes Management Program at Mount Sinai Beth Israel in New York, said, "In the younger age group where the information might be more valuable for preventing problems, not enough people pay attention to blood pressure and cholesterol levels". -Dr. Gerald Bernstein, Associate Clinical Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://mainenewsonline.com/content/15022680-younger-diabetic-patients-lacking-medical- care-study

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 4, 2015 Date: Wednesday, February 04, 2015 11:34:55 AM Attachments: ATT00001.txt

In the News February 4, 2015

Los Angeles Times – February 4 Why Cocaine Addicts Keep Making Bad Decisions – Geoffrey Mohan Chronic cocaine use alters brain circuits that help us learn from mistakes, a new study suggests. The study, published online Tuesday in the Journal of Neuroscience, could offer a biological marker for the cycle of destructive decisions that many addicts exhibit. This could explain why addicts will return to drugs despite the negative impacts of incarceration and loss of money, friends and family, according to the researchers. "They don't learn from it," said the study's lead researcher, Muhammad Parvaz, a cognitive neuroscientist at the Icahn School of Medicine at Mount Sinai in New York. - Muhammad Parvaz, PhD, Assistant Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.latimes.com/science/sciencenow/la-sci-sn-cocaine-addicts-decisions-20150203- story.html Additional Coverage: The Daily Mail: http://www.dailymail.co.uk/sciencetech/article-2938830/Cocaine-changes-addict-s- brains-t-recognise-loss-partner-leaves-sent-jail.html Medical Daily: http://www.medicaldaily.com/cocaine-effects-include-harm-done-brain-circuits-predict- loss-320614 Medical Xpress: http://medicalxpress.com/news/2015-02-cocaine-users-impaired-ability-loss.html The Indian Express: http://indianexpress.com/article/lifestyle/health/cocaine-use-impairs-loss- prediction-ability/ Medik Forum: http://www.medikforum.ru/news/health/treatment/37870-kokain-lishaet-cheloveka- chuvstva-utraty.html [Article is in Russian]

The Journal of the American Medical Association – February 3 Glutamate Control May Help Combat Age-Related Memory Loss – Tracy Hampton, PhD Riluzole, a drug that decreases glutamate release and increases glutamate uptake by astrocytes protects rats against some of the alterations in the brain that are linked to age-related memory loss, researchers report (published online December 15, 2014). The findings, from collaborators at the Rockefeller University and the Icahn School of Medicine at Mount Sinai in New York, suggest that novel glutamate modulators warrant further investigation as potentially promising agents to treat or even prevent cognitive decline. - Icahn School of Medicine at Mount Sinai Learn more: http://jama.jamanetwork.com/article.aspx?articleid=2107777

International Business Times – February 4 Why Slow-Cooking is Important? Study links High-Temperature Cooking to Alzheimer's – Roshni Mahesh Latest research shows that eating food cooked at high temperatures can increase a person's chances of developing Alzheimer's disease. "The findings point to an easily achievable goal that could reduce the risk of dementia through the consumption of non-AGE-rich foods, for example, foods that are cooked or processed under lower heat levels and in the presence of more water, raising the importance of not just what we eat, but also how we prepare what we eat," Jaime Uribarri, MD, and Weijing Cai of The Icahn School of Medicine at Mount Sinai said. -Dr. Jaime Uribarri, Professor, Medicine, Nephrology, Icahn School of Medicine at Mount Sinai -Weijing Cai, Senior Scientist, Geriatrics and Palliative Care, Icahn School of Medicine at Mount Sinai Learn more: http://www.ibtimes.co.in/why-slow-cooking-important-study-links-high-temperature- cooking-alzheimers-622434 Additional Coverage: The Times of India: http://timesofindia.indiatimes.com/home/science/Cook-in-low-flame-to-keep- Alzheimers-away/articleshow/46105540.cms India Today: http://indiatoday.intoday.in/story/low-flame-cooking-prevents-alzheimers- disease/1/416877.html

Bloomberg – February 3 Flu Shot May Be Upended as U.S. Tests Universal Vaccine – Anna Edney A universal influenza vaccine will be tested by U.S. researchers for the first time on people, a significant step toward ending the cumbersome method of developing a new flu shot every year to keep up with emerging strains of the virus. The universal vaccine has been shown effective in animal testing, and federal agencies plan to start the first of three phases of human testing in 2016, Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, said in a House Energy and Commerce Committee oversight panel hearing Tuesday. Others have been getting closer to human trials of the vaccines as well. Researchers at McMaster University and the Icahn School of Medicine at Mount Sinai in New York City published a paper last month in the Journal of Virology on a universal vaccine candidate that the NIH funded. - Icahn School of Medicine at Mount Sinai Learn more: http://www.bloomberg.com/news/articles/2015-02-03/flu-shot-ritual-may-be-upended-as- u-s-tests-universal-vaccine Additional Coverage: BioPharma Dive: http://www.biopharmadive.com/news/us-to-launch-large-scale-universal-flu-shot- testing-in-2016/360314/

Medpage Today – February 3 Patients Mum on Work-Related Asthma – Sanjay Gupta, MD While 46% of employed adults had asthma that was possibly work-related, only 15% of those patients discussed the relation between the workplace and their symptoms with their physician, according to a study published in the February issue of Annals of Allergy, Asthma and Immunology. In this video Beth Corn, MD, of the Mount Sinai Hospital discusses the study and provides suggestions on what physicians can do to help better physician-patient communication. - Dr. Beth Corn, Assistant Professor, Medicine, Clinical Immunology, Icahn School of Medicine at Mount Sinai Learn more: http://www.medpagetoday.com/AllergyImmunology/Allergy/49848

USA Today – February 3 Coke Gets Into Moo Juice with Premium-Price Milk – Bruce Horovitz Coca-Cola, the kingpin of carbonation, is about to get a milk mustache. The beverage giant announced on Tuesday that its Minute Made division is beginning to sell a premium-priced, protein-boosted milk under the Fairlife label. One nutritionist is unimpressed. "Milk is already an excellent nutritious beverage that does not require any engineering," says Rebecca Solomon, director of clinical nutrition at Mount Sinai Beth Israel in New York City. "I fail to see why milk needs to be improved upon by the soda industry." - Rebecca Solomon, MS, RD, CDN, Director, Clinical Nutrition, Mount Sinai Beth Israel Learn more: http://www.usatoday.com/story/money/2015/02/03/coca-cola-coke-fairlife-milk-premium- milk-dairy-nutrition/22798261/ Additional Coverage: KSDK.com: http://www.ksdk.com/story/life/2015/02/03/coke-to-sell-premium-milk-at-premium- price/22812195/

Prevention – February 3 The New Measles Outbreak: What Adults Need To Know About Their Own Vaccinations – Amber Brenza More than a decade after its declared elimination in 2000, measles has reared its ugly head again—at the "Happiest Place on Earth," of all locations. But tales of unvaccinated children and anti-vaccination parents have overshadowed a community just as at-risk for the virus (if not more so) as kids: grown-ups. If you were vaccinated, there's very little need to worry—even if it was eons ago. "Protection from the vaccine lasts for many decades and it's upwards of 95% effective during that time," says Roberto Posada, MD, professor of pediatrics and infectious diseases at Mount Sinai's Icahn School of Medicine. You may have heard that there was a second dose introduced to all measles vaccines in 1957, but those who got just one dose still likely have sufficient protection. - Dr. Roberto Posada, Associate Professor, Pediatrics, Infectious Diseases, Medical Education, Icahn School of Medicine at Mount Sinai Learn more: http://www.prevention.com/health/health-concerns/adult-measles

Tech Times – February 3 Medical Care Lacking For Younger Diabetics – James Maynard Younger diabetics are lacking access to medical care, compared to older people who suffer from the disease, according to the Centers for Disease Control and Prevention (CDC), said. The CDC report found that 19 percent of young American adults, aged 18 to 39, with diabetes had not visited with a medical professional in the last six months. Patients in this group were also less likely to have undergone a blood pressure or cholesterol check in the last 12 months than older people. "In the younger age group where the information might be more valuable for preventing problems, not enough people pay attention to blood pressure and cholesterol levels," Gerald Bernstein, MD, director of the Diabetes Management Program at Mount Sinai Beth Israel in New York, said. -Dr. Gerald Bernstein, Associate Clinical Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://www.techtimes.com/articles/30655/20150203/medical-care-lacking-younger- diabetics.htm Additional Coverage: WFMJ.com: http://www.wfmj.com/story/28010913/1-in-5-younger-diabetics-lacks-good-medical-care Diabetes Insider: http://diabetesinsider.com/younger-diabetics-make-better-effort-see-doctor/37737

WPIX TV – February 3 Supplement Shakedown Today, a new shocking investigation from the New York Attorney General’s office found that many of the herbal supplements purchased at stores were fakes. They found that 79% of the supplements tested had no DNA from the plants listed on the bottle. Marianne Camargo, MD, of The Mount Sinai Hospital added, “I think that a lot of the products out there are really mislabeled and we really don’t know what they contain.” She continues, “The best thing to do for your own health is to never smoke, to eat a healthy diet and exercise as allowed by your level of activity and fitness.” -Dr. Marianne Camargo, Assistant Professor, Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai Learn more: No Web Link Available

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 3, 2015 Date: Tuesday, February 03, 2015 3:21:30 PM Attachments: ATT00001.txt

In the News February 3, 2015

Prevention – February 3 The Breakfast Food That Helps You Eat 31% Less At Lunch – Victoria Wolk Eating oatmeal for breakfast makes you feel fuller, longer, and significantly reduces the number of calories you eat at lunch, according to new research published in the Annals of Nutrition & Metabolism. Just as researchers had predicted, the people who ate oatmeal were less hungry throughout the morning and ate about 31% fewer calories at lunch—despite being given the same number of calories at breakfast as the corn flakes group, says study author Allan Geliebter, PhD, a research psychologist at Mount Sinai St. Luke's Hospital in New York. - Allan Geliebter, PhD, Assistant Clinical Professor, Icahn School of Medicine at Mount Sinai Learn more: http://www.prevention.com/weight-loss/weight-loss-tips/oatmeal-suppresses-appetite

New Kerala – February 3 Cook in Low Flame to Keep Alzheimer's Away When food is cooked at high temperatures or aged for a long time such as in hard cheese, it increases the content of advanced glycation end products (AGEs), a group of compounds that are combinations of sugars and proteins and other large molecules. "We found that mice kept on a diet high in AGEs, similar to Western diet, had high levels of AGEs in their brains together with deposits of beta-amyloid proteins, a component of the plaques characteristic of Alzheimer's disease" said Jaime Uribarri, MD, and Weijing Cai of The Icahn School of Medicine at Mount Sinai, New York. -Dr. Jaime Uribarri, Professor, Medicine, Nephrology, Icahn School of Medicine at Mount Sinai -Weijing Cai, Senior Scientist, Geriatrics and Palliative Care, Icahn School of Medicine at Mount Sinai Learn more: http://www.newkerala.com/news/2015/fullnews-14274.html

Reuters – February 2 Transgender Kids Aren't Confused about Their Identities – Andrew Seaman Transgender youngsters identify as much with their genders as do non-transgender children, a new study says. The findings indicate that transgender children are not confused or delayed in their understanding of gender, as some have suggested, write the researchers in Psychological Science. The new study is an example of research in an area where it’s needed, said Barbara Warren, Psy.D, director of LGBT Programs and Policies in the Office of Diversity and Inclusion at Mount Sinai Health System in New York City. -Barbara E. Warren, Psy.D, LMHC, Director, LGBT Health Services, Mount Sinai Beth Israel, Mount Sinai Health System Learn more: http://www.reuters.com/article/2015/02/02/us-lgbt-transgender-pediatrics-idUSKBN0L62AP20150202

CNBC – February 3 Why Vaccines Can't Be a Choice: Disease Specialist – Matthew J. Belvedere The measles outbreak linked to Disneyland is raising new questions about whether children should be vaccinated, with health officials and politicians fueling new debate on both sides of this issue. "It really is not just a personal choice but a public health issue, Gail Shust, MD, pediatrician and infectious disease specialist at Mount Sinai Hospital in New York City, told CNBC on Tuesday."If a person decides not to vaccinate their child, not only are they potentially putting their child's health at risk, but they're also putting other people at risk." - Dr. Gail Shust, Assistant Professor Medical Education, Pediatrics, Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: http://www.cnbc.com/id/102392796#.

The Wall Street Journal – February 2 Researchers Say When You Eat Each Day May Be Crucial to Weight Loss – Angela Chen Most diet advice focuses on calories and nutrients, but new research suggests that when you eat may be just as important. Christopher Ochner, a director of research development at Mount Sinai Hospital who focuses on obesity, warns that studies of time-restricted feeding may be the latest in a long line of mice studies that don’t translate to people. He says the old idea of “calories in, calories out” matters more for health than how many hours someone eats, or what time of day they are eating. -Christopher Ochner, PhD, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.wsj.com/articles/researchers-say-when-you-eat-each-day-may-be-crucial-to-weight-loss-1422901628? mod=trending_now_3

Healthday – February 3 1 in 5 Younger Diabetics Lacks Good Medical Care, Study Says – E.J. Mundell One in every five young American adults with diabetes hasn't seen a doctor in the past 6 months, a new government report indicates. Gerald Bernstein, MD, FACP, added that the new statistics only look at the "tip of the iceberg," because "underneath are millions of people with pre- diabetes, most of whom are not diagnosed." Bernstein directs the diabetes management program at Mount Sinai Beth Israel Hospital in New York City. "During the pre-diabetic phase there is festering deterioration, especially the cardiovascular system, so that by the time the diagnosis of clinical diabetes is made, many already have impairment that was preventable," he said. -Dr. Gerald Bernstein, Associate Clinical Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/diabetes-information-10/misc-diabetes-news-181/1-in-5-younger-diabetics-lack-good-medical-care- 696019.html Additional Coverage: Philly.com: http://www.philly.com/philly/health/diabetes/HealthDay696019_20150203_1_in_5_Younger_Diabetics_Lacks_Good_Medical_Care__Study_Says.html

Medpage Today – February 3 Mixed Data on Diabetes Care in U.S. Patients – Parker Brown The percentage of adults with the diabetes who were taking medication to control glucose levels increased with age, as did the percentage of those that had contact with an eye or foot care specialists in the past year. "This tells us that people seeking medical care is remarkably high after a diagnosis of diabetes is made, including care from foot and eye doctors," wrote Gerald Bernstein, MD, FACP, director of the Diabetes Management Program at Mount Sinai Beth Israel in New York City. "In the younger age group where the information might be more valuable for preventing problems, not enough people pay attention to blood pressure and cholesterol levels." -Dr. Gerald Bernstein, Associate Clinical Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://www.medpagetoday.com/Endocrinology/Type1Diabetes/49845/

Healthday – February 2 U.S. Measles Cases Now Exceed 100: CDC – Dennis Thompson Many parents aren't getting their children vaccinated against measles, due largely to what experts call mistaken fears about childhood vaccines. A big contributing factor to the parents' continuing concerns about vaccine safety was a 1998 fraudulent paper published and later retracted in the medical journal The Lancet. Michael Tosi, MD, chief of pediatric infectious diseases at the Kravis Children's Hospital at Mount Sinai in New York City, said, "Any concerns or claims about a connection between measles vaccine and autism in young children have absolutely no scientific basis and have been entirely discredited." - Dr. Michael Tosi, Clinical Professor, Pediatrics, Infectious Diseases, Icahn School of Medicine at Mount Sinai, Chief of Pediatric Infectious Diseases, Kravis Children’s Hospital at Mount Sinai Learn more: http://consumer.healthday.com/public-health-information-30/centers-for-disease-control-news-120/more-measles-cases-seen-in- january-than-in-typical-year-cdc-696083.html Additional Coverage: U.S. News & World Report: http://health.usnews.com/health-news/articles/2015/02/02/us-measles-cases-now-exceed-100-cdc Medical Xpress: http://medicalxpress.com/news/2015-02-measles-cases-cdc.html Health.com: http://news.health.com/2015/02/02/u-s-measles-cases-now-exceed-100-cdc/

Healthday – February 2 Many Americans Face Pain, Depression in Their Final Year – Amy Norton For a growing number of Americans, the final year of life is marked by pain, depression and other distressing symptoms, a new study finds. Experts said the study, published Feb. 2 in Annals of Internal Medicine, highlights disturbing shortcomings in the U.S. health care system. "I think the findings are very valid, but the conclusions about what they mean are not," said Sean Morrison, MD, who directs the Hertzberg Palliative Care Institute at Mount Sinai’s Icahn School of Medicine in New York City. "I think you'd see a high prevalence of these symptoms if you looked at older adults' last two years of life, or last three, or last five," Morrison said. - Dr. R. Sean Morrison, Hermann Merkin Professor in Palliative Care, Professor, Anesthesiology, Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/senior-citizen-information-31/misc-death-and-dying-news-172/many-americans-face-pain- depression-in-their-final-year-696087.html Additional Coverage: U.S. News & World Report: http://health.usnews.com/health-news/articles/2015/02/02/many-americans-face-pain-depression-in-their-final-year Doctors Lounge: http://www.doctorslounge.com/index.php/news/hd/52776 Newsmax: http://www.newsmaxhealth.com/Health-News/hospice-pain-depression/2015/02/03/id/622315/

Yahoo Health – February 3 Nearly 45% of Younger Americans Have This Silent Health Risk – Jenna Birch One in 10 American adults has diabetes mellitus. In some ways, we’re taking better care of treatment for the chronic condition, but in other ways, we’re in need of major improvements. Gerald Bernstein, MD, FACP, director of the Diabetes Management Program at Mount Sinai Beth Israel, says that this is an area in which we need to do better, as monitoring blood pressure and cholesterol can help minimize risk of heart attack, stroke and other diseases — especially among the youngest group of diabetes sufferers, who have more years of risk ahead of them. -Dr. Gerald Bernstein, Associate Clinical Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: https://www.yahoo.com/health/nearly-45-of-younger-americans-have-this-silent-109970720977.html

Yahoo via Health.com – February 2 5 Things You Definitely Should Not Be Doing to Your Vagina – Hallie Levine Just when we thought we’d heard it all, Gwyneth Paltrow recently touted the restorative powers of $50 vaginal steam treatments on her website, Goop. Paltrow offers huge raves for Tikkun Spa’s Mugwort V-Steam: “You sit on what is essentially a mini-throne, and a combination of infrared and mugwort steam cleanses your uterus, et al,” the Oscar winner explains. But OB/GYNs call her bluff. The steam itself can increase moisture in and around your nether regions, making you more susceptible to the growth of yeast and unfriendly bacteria, points out Taraneh Shirazian, MD, an OB/GYN at the Mount Sinai Hospital in New York City. - Dr. Taraneh Shirazian, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: https://www.yahoo.com/health/5-things-you-definitely-should-not-be-doing-to-109893622473.html

New Haven Register – February 2 New genomics research facility in Branford will expand capacity – Luther Turmelle The Icahn School of Medicine at the Mount Sinai genomics research facility on Commercial Street is expected to more than double its workforce over the remainder of this year by adding another 30 employees. The 16,500-square-foot facility, which opened last fall and has a staff of 19 people, hosted a reception last week to show off the research center to the community. Andrew Kasarskis, co-director of the Icahn Institute for Genomics, said the New Haven area “has a good framework” in place for the research and biotechnology industries. -Andrew Kasarkis, PhD, Associate Professor, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Co-Director, Icahn Institute for Genomics and Multiscale Biology - Todd E. Arnold, PhD, Managing Director, The Mount Sinai Genetic Testing Laboratory - Connecticut Learn more: http://www.nhregister.com/general-news/20150202/new-genomics-research-facility-in-branford-will-expand-capacity

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: [email protected] on behalf of Lindo, Allisa Subject: Mount Sinai In The News - February 2, 2015 Date: Monday, February 02, 2015 2:14:06 PM Attachments: ATT00001.txt

In the News February 2, 2015

The New York Daily News – January 29 Breakthrough 'Artificial Pancreas' Helps Control Diabetic’s Insulin Levels – Meredith Engel For most of her life, Alecia Wesner has been haunted by type 1 diabetes, a disease that never lets her get a good night’s sleep. But for nearly a week in November, she got the best rest of her life, thanks to a revolutionary smartphone tool that regulated her insulin pump. “The beauty of the system is that it anticipates what is coming and makes adjustments proactively," Carol Levy, MD, an endocrinologist at the Mount Sinai Diabetes Center and the lead investigator of the study, told the Daily News. - Dr. Carol Levy, Associate Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://www.nydailynews.com/life-style/health/cell-biology-breakthrough-app-controls- diabetic-insulin-article-1.2095625

The New York Times – February 2 How to Measure a Medical Treatment’s Potential for Harm – Aaron E. Carroll and Austin Frakt As we wrote last week, many fewer people benefit from medical therapies than we tend to think. This fact is quantified in a therapy’s Number Needed to Treat, or N.N.T., which tells you the number of people who would need to receive a medical therapy in order for one person to benefit. A wealth of N.N.T. and N.N.H. data based on clinical trials is available on a website developed by David Newman, MD, a director of clinical research at Icahn School of Medicine at Mount Sinai hospital, and Graham Walker, an assistant clinical professor at the University of California, San Francisco. -Dr. David Newman, Director of Clinical Research, Department of Emergency Medicine, Associate Professor of Emergency Medicine at Icahn School of Medicine at Mount Sinai Learn more: http://www.nytimes.com/2015/02/03/upshot/how-to-measure-a-medical-treatments- potential-for-harm.html?_r=0&abt=0002&abg=1

ABC News – February 2 How a Triathlete Who Died During a Race Is Still Alive Today – Sydney Lupkin Chris LaPak died in August. The fact that he woke up five days later and is alive today is a "miracle," he said. Lifeguards on surfboards spotted his body in the water and pulled him onto a surfboard, taking care to keep his head above water. They took him to a jet ski and then a fire department boat before making it to the dock, an ambulance, Roosevelt Hospital and, finally, Mount Sinai St. Luke's Hospital. Eyal Herzog, MD, happened to be at work that Sunday, and followed protocols to cool LaPak down to 33 degrees Celsius, or 94.1 degrees Fahrenheit, to protect his brain and give it a chance to recover. - Dr. Eyal Herzog, Associate Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director of Cardiac Care Unit, Mount Sinai St. Luke’s Learn more: http://abcnews.go.com/Health/triathlete-died-race-alive-today/story?id=28617114 Additional Coverage: The Daily Mail: http://www.dailymail.co.uk/news/article-2936418/Triathlete-dead-11-minutes-heart- stopped-race-miraculously-woke-five-days-later.html

MSNBC – January 31 The Measles are Back in America – Melissa Harris-Perry In the year 2000, measles had been eliminated in the United States. But now a measles outbreak is making its way back in the headlines. Measles is one of the most contagious diseases in the world. Measles is marked by a high fever, a rash all over the body, coughing and red watery eyes, as well as sensitivity to light. 2014 was the worst year for measles since the disease was declared eliminated in 2000. Gail Shust, MD, joins Melissa Harris-Perry to talk about the recent measles outbreak. - Dr. Gail Shust, Assistant Professor Medical Education, Pediatrics, Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: http://www.msnbc.com/melissa-harris-perry/watch/the-measles-are-back-in-america- 391834691762

Yahoo Health – February 2 Are E-Cigarettes Heroes or Harmful? A Look at the Science – Jenna Birch Research has indicated that e-cigarettes help people slow their tobacco consumption, like a November 2014 study that showed six months of vaping led 21 percent of participants to quit traditional cigarettes, with an additional 23 percent cutting back by half. According to Charles Powell, MD, chief of pulmonary medicine at the Mount Sinai Hospital and a professor of medicine at the Icahn School of Medicine at Mount Sinai in New York City, “They are essentially a delivery device for nicotine,” he tells Yahoo Health. - Dr. Charles Powell, Professor, Medicine, Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, Chief, Pulmonary Medicine, The Mount Sinai Hospital Learn more: https://www.yahoo.com/health/are-e-cigarettes-heros-or-harmful-a-look-at-the- 109612248742.html

Yahoo Health – January 30 Will The Super Bowl Spark Another Disneyland-Like Measles Outbreak? – Jenna Birch As thousands make their way toward Phoenix, Arizona for the Super Bowl on Sunday, state health officials are monitoring more than 1,000 people who have come in contact with the measles virus, including 195 children, as a result of the Disneyland outbreak in California. If anyone ignores symptoms and attends the game, however, that could be potentially damaging, as the disease spreads fast among the unvaccinated, according to Gail Shust, MD, a pediatric infectious disease specialist at the Kravis Children’s Hospital at Mount Sinai. - Dr. Gail Shust, Assistant Professor Medical Education, Pediatrics, Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: https://www.yahoo.com/health/will-the-super-bowl-spark-another-disneyland-like- 109582173247.html Additional Coverage: Sporting News: http://www.sportingnews.com/nfl/story/2015-01-30/health-officials-warn-those-with- measles-symptoms-to-stay-away-from-super-bowl

Yahoo Beauty via Your Tango – January 29 5 Ways Hormones Mess With Your Appearance – Aly Walansky Hormones cause oil glands to enlarge and to produce more oil during puberty and throughout the teen years. Hormonal fluctuations are strongly correlated with acne breakouts, says Joshua Zeichner, MD, Assistant Professor of Dermatology at the Icahn School of Medicine at Mount Sinai. As hormones surge, for example in the middle of your menstrual period, oils glands in the skin react. The hormones cause the glands to go into overdrive, revving up oil production. This translates into more food for acne- causing bacteria and can clog pores. - Dr. Joshua Zeichner, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: https://www.yahoo.com/beauty/5-sly-ways-hormones-mess-with-your-appearance- 108740162298.html

Allure – January 30 You're Probably Applying Your Eye Cream Wrong – Kate Sullivan The best beauty advice is often kind of amazingly duh. I recently had a duh moment when talking to Jeannette Graf, a clinical professor of dermatology at the Icahn School of Medicine at Mount Sinai in New York City, about how you should be putting on your eye cream. - Dr. Jeannette Graf, Assistant Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.allure.com/beauty-trends/blogs/daily-beauty-reporter/2015/01/eye-cream- application.html

WPIX – January 29 Inside a High Security Methadone Clinic in Manhattan – Mary Murphy The white, plastic bottles containing the reddish-pink liquid that is Methadone were locked inside a safe, inside a locked closet, when PIX 11 News visited Mount Sinai’s 25th Street clinic on Second Avenue. Regina Jeter-Jemmott, a registered nurse, showed us the rituals she goes through every day to make sure the machine is calibrating Methadone doses accurately, before she begins dispensing the cups for recovering heroin addicts. “About 50,000 people are on Methadone in New York City,” said Dr. Don DesJarlais, long-time director of the Baron Edmund de Rothschild Chemical Dependency Institute at Mount Sinai Beth Israel. -Dr. Don Des Jarlais, Director, Baron Edmund de Rothschild Chemical Dependency Institute, Mount Sinai Beth Israel Learn more: http://pix11.com/2015/01/29/inside-a-high-security-methadone-clinic/

The Day – February 2 Branford Genetics Lab a Boon for Region – Lee Howard Pretty soon, it will cost only $1,000 to get a complete genome sequence from a bit of human blood or saliva - down from $200,000 a few years ago and, before that, perhaps $2 million. With costs deflating while the capacity of machines to process huge amounts of data at one time continues to escalate, the New York City-based Icahn School of Medicine at Mount Sinai is betting that its newly renovated genetic testing laboratory here will make a major impact. - Todd E. Arnold, PhD Managing Director, the Mount Sinai Genetic Testing Laboratory - Connecticut Learn more: http://www.theday.com/local/20150202/branford-genetics-lab-a-boon-for-region

Medical Daily – February 1 Common Household Pesticides May Double Risk Of ADHD in Kids Exposed To Chemicals during Pregnancy, Breastfeeding – Anthony Rivas Speaking to Rodale in 2011 about another study linking pesticides to ADHD, Phil Landrigan, MD, professor and chair of the Department of Community and Preventive Medicine at the Icahn School of Medicine at Mount Sinai, said: “It’s been shown that people who switch to an organic diet knock down the levels of pesticide byproducts in their urine by 85 to 90 percent.” That 2010 study, by the way, found a 35 percent increase in ADHD risk for every 10-fold increase in urinary concentrations of pesticide metabolites. - Dr. Philip Landrigan, Professor and System Chair, Preventative Medicine, Professor, Pediatrics, Dean for Global Health, Icahn School of Medicine at Mount Sinai Learn more: http://www.medicaldaily.com/common-household-pesticides-may-double-risk-adhd-kids- exposed-chemicals-during-320356

Medical Daily – January 31 Oral Immunotherapy Combination of Peanut Protein, Probiotics May Cure Peanut Allergies – Lecia Bushak In the past several decades, the number of children with peanut allergies has tripled from 0.4 percent in 1997 to 1.4 percent in 2010, according to an Icahn School of Medicine at Mount Sinai study. While doctors aren’t certain what caused the increase, it has led schools and airlines to ban peanut products out of fear of causing severe reactions. - Icahn School of Medicine at Mount Sinai Learn more: http://www.medicaldaily.com/oral-immunotherapy-combination-peanut-protein- probiotics-may-cure-peanut-allergies-320268

IRINnews.org – February 2 Has Syria Really Beaten Polio? – Danya Chudacoff and Louise Redvers The World Health Organization has announced that Syria has seen no new cases of polio in the past year, but some health experts question the quality of the surveillance that led to this conclusion. Just 10 months ago, a UN official labeled the outbreak in Syria, and its subsequent spread to Iraq, as “the most challenging… in the history of polio eradication”. “The absence of laboratory evidence of polio does not mean the absence of polio,” said Annie Sparrow, assistant professor of global health and deputy director of the Human Rights Program at Icahn School of Medicine at Mount Sinai in New York City, who for the past year has been advising Syrian opposition aid workers on polio response. - Dr. Annemarie Sparrow, Assistant Professor, Preventative Medicine, Pediatrics, Icahn School of Medicine at Mount Sinai, Human Rights Director, the Arnhold Global Health Institute at Mount Sinai Learn more: http://www.irinnews.org/report/101076/has-syria-really-beaten-polio

Health Aim – February 2 3 Symptoms That Show You Are Gluten-Sensitive – Kaustav Gluten related disorders are generally known as Celiac Disease and Non-Celiac Gluten Sensitivity (NCGS). It has come to attention to most of the health officials around the world that people have gone gluten-free because they have gastrointestinal issues, but they have done it on their own and without consulting a doctor. In some cases this may turn out to be alright but in others, this can turn out to be a mistake. Gina Sam, MD, director of the Mount Sinai Gastrointestinal Motility Center at The Mount Sinai Hospital points out certain symptoms which, if you are showing, require a must medical consultation. - Dr. Gina Sam, Assistant Professor, Medicine, Gastroenterology, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Gastrointestinal Motility Center at the Mount Sinai Hospital Learn more: http://www.healthaim.com/3-symptoms-that-show-you-are-gluten-sensitive/11846

The New York Daily News – February 1 Winter's Cold Weather Brings Its Own Set of Health Dangers – Katie Charles Regardless of what Punxsutawney Phil says, New Yorkers know they have months of cold weather left ahead — so what should we all be doing to protect our hearts from cold injury? “Every season has its challenges, but winter cold actually puts additional strain on the heart, as do many winter activities — whether it’s shoveling snow or just staying upright on an icy sidewalk,” says Robert Gotlin, MD. - Dr. Robert Gotlin, Associate Professor, Rehabilitation Medicine, Orthopaedics, Icahn School of Medicine at Mount Sinai, Director, Orthopaedic and Sports Rehabilitation, Mount Sinai Beth Israel Learn more: http://www.nydailynews.com/life-style/health/daily-checkup-winter-cold-weather- dangers-article-1.2092359

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