Experiencing Sensation and Perception Page 6.1 Chapter 6: Color Vision
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Sensitivities in Older Eyes with Good Acuity: Cross-Sectional Norms
Sensitivities in Older Eyes With Good Acuity: Cross-Sectional Norms Alvin Eisner,*f Susan A. Fleming,*! Michael L. Kleins and W. Manning Mauldinf We measured several indices of foveal visual function for a large group of people aged 60 and older. The data reported in this paper are from individuals who had good acuity in each eye and met a number of other criteria for good ocular health. For each index, we described the rate of cross-sectional change with age using linear regression statistics. We found age-related change for eyes having 20/20 or better acuity to exist for several different indices. Sensitivity mediated by the blue-sensitive cones decreased with age, as expected. However, the rate of decrease was faster for females than for males. At least part of the difference was associated with different rates of lenticular change. Absolute sensitivity at long wavelengths also decreased with age, but at the same rate for each sex. Rayleigh color matches changed with age in a manner consistent with underlying age-related decreases of effective foveal cone photopigment density. However, not all indices showed age-dependent changes. For instance, the time constant describing the rate of photopic dark adaptation did not appear to change with age. Invest Ophthalmol Vis Sci 28:1824-1831, 1987 Human visual function changes with age. Cross- criteria for good ocular health in each eye. In particu- sectional age-related changes have been reported for lar, we have tested people having good acuity in each Snellen acuity,1 spatial2"4 and temporal4 contrast sen- eye. -
ERG), Molecular and Behavioral Studies
Vision Research 38 (1998) 3377–3385 Severity of color vision defects: electroretinographic (ERG), molecular and behavioral studies M.A. Crognale a,b,*, D.Y. Teller a,c, A.G. Motulsky d,e, S.S. Deeb d,e a Department of Psychology, Uni6ersity of Washington, Box 351525, Seattle, WA 98195-1525, USA b Department of Ophthalmology, Uni6ersity of Washington, Seattle, WA, USA c Department of Physiology/Biophysics, Uni6ersity of Washington, Seattle, WA, USA d Department of Genetics, Uni6ersity of Washington, Seattle, WA, USA e Department of Medicine, Uni6ersity of Washington, Seattle, WA, USA Received 10 July 1997; received in revised form 29 October 1997 Abstract Earlier research on phenotype/genotype relationships in color vision has shown imperfect predictability of color matching from the photopigment spectral sensitivities inferred from molecular genetic analysis. We previously observed that not all of the genes of the X-chromosome linked photopigment gene locus are expressed in the retina. Since sequence analysis of DNA does not necessarily reveal which of the genes are expressed into photopigments, we used ERG spectral sensitivities and adaptation measurements to assess expressed photopigment complement. Many deuteranomalous subjects had L, M, and L–M hybrid genes. The ERG results showed that M pigment is not present in measurable quantities in deutan subjects. Using these results to determine gene expression improved the correlations between inferred pigment separation and color matching. Furthermore, we found a subject who had normal L and M genes and normal proximal promoter sequences, yet he had a single photopigment (M) by ERG and tested as a protanope. These results demonstrate the utility of ERG measurements in studies of molecular genetics of color vision deficiencies, and further support the conclusion that not all genes are expressed in color deficient subjects. -
The Genetics of Normal and Defective Color Vision
Vision Research xxx (2011) xxx–xxx Contents lists available at ScienceDirect Vision Research journal homepage: www.elsevier.com/locate/visres Review The genetics of normal and defective color vision Jay Neitz ⇑, Maureen Neitz University of Washington, Dept. of Ophthalmology, Seattle, WA 98195, United States article info a b s t r a c t Article history: The contributions of genetics research to the science of normal and defective color vision over the previ- Received 3 July 2010 ous few decades are reviewed emphasizing the developments in the 25 years since the last anniversary Received in revised form 25 November 2010 issue of Vision Research. Understanding of the biology underlying color vision has been vaulted forward Available online xxxx through the application of the tools of molecular genetics. For all their complexity, the biological pro- cesses responsible for color vision are more accessible than for many other neural systems. This is partly Keywords: because of the wealth of genetic variations that affect color perception, both within and across species, Color vision and because components of the color vision system lend themselves to genetic manipulation. Mutations Cone photoreceptor and rearrangements in the genes encoding the long, middle, and short wavelength sensitive cone pig- Colorblindness Cone mosaic ments are responsible for color vision deficiencies and mutations have been identified that affect the Opsin genes number of cone types, the absorption spectra of the pigments, the functionality and viability of the cones, Evolution and the topography of the cone mosaic. The addition of an opsin gene, as occurred in the evolution of pri- Comparative color vision mate color vision, and has been done in experimental animals can produce expanded color vision capac- Cone photopigments ities and this has provided insight into the underlying neural circuitry. -
A New Test System and a New Cause for Acquired Foveal Color-Vision Deficiency
International Journal of Ophthalmology & Visual Science 2016; 1(1): 8-19 http://www.sciencepublishinggroup.com/j/ijovs doi: 10.11648/j.ijovs.20160101.12 A New Test System and a New Cause for Acquired Foveal Color-Vision Deficiency Terry Bahill Systems and Biomedical Engineering, University of Arizona, Tucson Arizona, USA Email address: [email protected] To cite this article: Terry Bahill. A New Test System and a New Cause for Acquired Foveal Color-vision Deficiency. International Journal of Ophthalmology & Visual Science. Vol. 1, No. 1, 2016, pp. 8-19. doi: 10.11648/j.ijovs.20160101.12 Received: August 22, 2016; Accepted: November 8, 2016; Published: December 2, 2016 Abstract: The purpose of this paper is to show a new cause of a macular scotoma and an anomalous acquired color-vision deficiency in the clinical fovea caused by retina detachments and subsequent surgeries. This deficiency was measured with a visual test system composed of multiple lasers, a white light beam and dozens of targets that were projected on a computer monitor and printed on paper. Lasers were used, because they produce small monochromatic target dots, 0.07 degrees of visual angle (6 mm) in diameter. The outputs of the system were the subject’s perceived color matches. In experiments with small dots of laser light, colors were judged correctly by the right eye (OD): however, the left eye (OS) could not distinguish colors. For example, a green laser dot appeared green to his OD and white to his OS. Perceived color in the abnormal OS depended on the target’s hue, saturation, luminance, wavelength, size and position on the fovea. -
Defective Color Vision and Its Inheritance by George Wald*
DEFECTIVE COLOR VISION AND ITS INHERITANCE BY GEORGE WALD* BIOLOGICAL LABORATORIES, HARVAkRD IJNIVERSITY We owe the first accurate description of color blindness to the chemist John Dalton, who in 1798 characterized his own condition in the words 'persons in general dis- tinguish six kinds of colour in the solar image; namely, red, orange, yellow, green, blue, and purple.... To me it is quite otherwise:-I see only two, or at most three, distinctions. These I should call yellow and blue; or yellow, blue, and purple. MiIy yellow comprehends the red, orange, yellow, and green of others; and my blue and purple coincide with theirs. That part of the image which others call red, ap- pears to me little more than a shade, or defect of light....". In this superb paper, Dalton set all the main themes for the study of color blindness. He pointed out that his vision had always been this way; that his brother had the same defect; that he knew of nearly 20 such cases, all male; and that in all but perhaps one in- stance the parents and children of such persons had normal vision.' Dalton thought the trouble to be that his vitreous humor was tinted blue, and so did not pass red light; but Thomas Young said of this: ". it is much more simple to suppose the absence or paralysis of those fibers of the retina which are calculated to perceive red."2 Dalton held to his own view, and the argument was settled only by autopsy at his death in 1842, when his eyes were found to be normally trans- parent to red light.3 Color blindness is still called daltonism throughout Europe; but Young's explanation, that it involves the loss of one of three normal color mechanisms, remained for many years the dominant theory of this condition. -
Cortical Color Loss and the Chromatic Visual Evoked Potential Department of Psychology, Program in Cognitive and # Michael A
Journal of Vision (2013) 13(10):15, 1–11 http://www.journalofvision.org/content/13/10/15 1 The locus of color sensation: Cortical color loss and the chromatic visual evoked potential Department of Psychology, Program in Cognitive and # Michael A. Crognale Brain Sciences, University of Nevada, Reno, NV, USA $ Department of Psychology, Program in Cognitive and Chad S. Duncan Brain Sciences, University of Nevada, Reno, NV, USA $ Department of Psychology, Program in Cognitive and Hannah Shoenhard Brain Sciences, University of Nevada, Reno, NV, USA $ Department of Psychology, Program in Cognitive and Dwight J. Peterson Brain Sciences, University of Nevada, Reno, NV, USA $ Department of Psychology, Program in Cognitive and # Marian E. Berryhill Brain Sciences, University of Nevada, Reno, NV, USA $ Color losses of central origin (cerebral achromatopsia and dyschromatopsia) can result from cortical damage Introduction and are most commonly associated with stroke. Such cases have the potential to provide useful information Color vision can be disrupted or lost by a number of regarding the loci of the generation of the percept of causes, the most common being genetic mutations. color. One available tool to examine this issue is the Achromatopsia is a condition wherein the percept of chromatic visual evoked potential (cVEP). The cVEP has colors is absent. Much more common is dyschroma- been used successfully to objectively quantify losses in topsia wherein there is a partial loss of color capacity. color vision capacity in both congenital and acquired Many cases of achromatopsia and most cases of deficiencies of retinal origin but has not yet been applied to cases of color losses of cortical origin. -
Comparison of Farnsworth and Lanthony D-15 Color Vision Tests to an Computerized Color Vision Cap Rearrangement Test James Kundart Pacific Nu Iversity
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by CommonKnowledge Pacific nivU ersity CommonKnowledge Faculty Scholarship (COO) College of Optometry 2006 Comparison of Farnsworth and Lanthony D-15 Color Vision Tests to an Computerized Color Vision Cap Rearrangement Test James Kundart Pacific nU iversity Karl Citek Pacific nU iversity Follow this and additional works at: http://commons.pacificu.edu/coofac Part of the Optometry Commons Recommended Citation Kundart, James and Citek, Karl, "Comparison of Farnsworth and Lanthony D-15 Color Vision Tests to an Computerized Color Vision Cap Rearrangement Test" (2006). Faculty Scholarship (COO). Paper 27. http://commons.pacificu.edu/coofac/27 This Poster is brought to you for free and open access by the College of Optometry at CommonKnowledge. It has been accepted for inclusion in Faculty Scholarship (COO) by an authorized administrator of CommonKnowledge. For more information, please contact [email protected]. Comparison of Farnsworth and Lanthony D-15 Color Vision Tests to an Computerized Color Vision Cap Rearrangement Test Description Inherited color vision deficiency affects approximately 8% of the male Caucasian population, 5% of non- Caucasian males, and 0.4% of all women. In addition, significant numbers of patients of both genders acquire color vision loss due to ocular disease or pharmaceutical medications. Yet in many clinical settings color vision testing presents a challenge because plate tests, like those designed by Ishihara, do not easily differentiate green (deutan) from red (protan) defects. Tests that do differentiate, like the Farnsworth D-15, show false positive results with mild to moderate anomalous trichromacy, and are time- consuming. -
A Bilateral Color Anomaly in the Crayfish, Orconectes Immunis (Hagen)
Proceedings of the Iowa Academy of Science Volume 76 Annual Issue Article 64 1969 A Bilateral Color Anomaly in the Crayfish, Orconectes immunis (Hagen) Virgil E. Dowell University of Northern Iowa Leonard P. Winier University of Northern Iowa Let us know how access to this document benefits ouy Copyright ©1969 Iowa Academy of Science, Inc. Follow this and additional works at: https://scholarworks.uni.edu/pias Recommended Citation Dowell, Virgil E. and Winier, Leonard P. (1969) "A Bilateral Color Anomaly in the Crayfish, Orconectes immunis (Hagen)," Proceedings of the Iowa Academy of Science, 76(1), 487-492. Available at: https://scholarworks.uni.edu/pias/vol76/iss1/64 This Research is brought to you for free and open access by the Iowa Academy of Science at UNI ScholarWorks. It has been accepted for inclusion in Proceedings of the Iowa Academy of Science by an authorized editor of UNI ScholarWorks. For more information, please contact [email protected]. Dowell and Winier: A Bilateral Color Anomaly in the Crayfish, Orconectes immunis (Ha A Bilateral Color Anomaly in the Crayfish, Orconectes immunis (Hagen) VIRGIL E. DOWELL AND LEONARD P. WINIER1 Abstract. A live female crayfish; Orconectes immunis (Hagen) exhibit ing unusual body coloration was given to the biology laboratories at the University of Northern Iowa for study. Its right half, including antennae and other appendages, was colored an azure blue; the left half was colored normally. This bilateral coloration mosaicism persisted foUowing molting. Gynandromorphism as a corollary factor is eliminated on the basis that no apparent external sexual intergradation of sexual dimorphism was notice able. -
On the Nature of Unique Hues
Reprinted from Dickinson, C., Murray, 1. and Carden, D. (Eds) 'John Dalton's Colour Vision Legacy', 1997, Taylor & Francis, London On the Nature of Unique Hues J. D. Mollon and Gabriele Jordan 7.1 .l INTRODUCTION There exist four colours, the Urfarben of Hering, that appear phenomenologically un- mixed. The special status of these 'unique hues' remains one of the central mysteries of colour science. In Hering's Opponent Colour Theory, unique red and green are the colours seen when the yellow-blue process is in equilibrium and when the red-green process is polarised in one direction or the other. Similarly unique yellow and blue are seen when the red-green process is in equilibrium and when the yellow-blue process is polarised in one direction or the other. Most observers judge that other hues, such as orange or cyan, partake of the qualities of two of the Urfarben. Under normal viewing conditions, however, we never experience mixtures of the two components of an opponent pair, that is, we do not experience reddish greens or yellowish blues (Hering, 1878). These observations are paradigmatic examples of what Brindley (1960) called Class B observations: the subject is asked to describe the quality of his private sensations. They differ from Class A observations, in which the subject is required only to report the identity or non- identity of the sensations evoked by different stimuli. We may add that they also differ from the performance measures (latency; frequency of error; magnitude of error) that treat the subject as an information-processingsystem and have been increasingly used in visual science since 1960. -
Unique Hues & Principal Hues
Received: 19 June 2018 Revised and accepted: 6 July 2018 DOI: 10.1002/col.22261 RESEARCH ARTICLE Unique hues and principal hues Mark D. Fairchild Program of Color Science/Munsell Color Science Abstract Laboratory, Rochester Institute of Technology, Integrated Sciences Academy, Rochester, This note examines the different concepts of encoding hue perception based on New York four unique hues (like NCS) or five principal hues (like Munsell). Various sources Correspondence of psychophysical and neurophysiological information on hue perception are Mark Fairchild, Rochester Institute of Technology, Integrated Sciences Academy, Program of Color reviewed in this context and the essential conclusion that is reached suggests there Science/Munsell Color Science Laboratory, are two types of hue perceptions being quantified. Hue discrimination is best quan- Rochester, NY 14623, USA. tified on scales based on five, equally spaced, principal hues while hue appearance Email: [email protected] is best quantified using a system based on four unique hues as cardinal axes. Much more remains to be learned. KEYWORDS appearance, discrimination, hue, Munsell 1 | INTRODUCTION note that the NCS system was designed to specify colors and their relations according to the character of their perception For over a century, the Munsell Color System has been used (appearance) while Munsell was set up to create scales of to describe color appearance, specify color relations, teach equal color discrimination, or color difference (rather than color concepts, and inspire new uses of color. It is unique in perception). Perhaps that distinction can be used to explain the sense that its hue dimension is anchored by five principal the difference in number of principal/cardinal hues. -
Ishihara Electronic Color Blindness Test: an Evaluation Study
Ophthalmology Research: An International Journal 3(3): 67-75, 2015, Article no.OR.2015.012 ISSN: 2321-7227 SCIENCEDOMAIN international www.sciencedomain.org Ishihara Electronic Color Blindness Test: An Evaluation Study Hatem M. Marey1*, Noura A. Semary2 and Sameh S. Mandour1 1Ophthalmology Department, Faculty of Medicine Menofia University, Shebin El-Kom, Egypt. 2Faculty of Computers and Information Menofia University, Shebin El-Kom, Egypt. Authors’ contributions This work was carried out in collaboration between all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/OR/2015/13618 Editor(s): (1) Jimmy S.M. Lai, Department of Ophthalmology, The University of Hong Kong, Hong Kong and Honorary Consultant Ophthalmologist, Queen Mary Hospital, Hong Kong. (2) Li Wang, Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, USA. Reviewers: (1) Anonymous, India. (2) Anonymous, Canada. (3) Ricardo Franco de Lima, Department of Neurology, State University of Campinas (UNICAMP), Brazil. (4) Anonymous, Turkey. Complete Peer review History: http://www.sciencedomain.org/review-history.php?iid=889&id=23&aid=7361 Received 25th August 2014 th Original Research Article Accepted 19 November 2014 Published 16th December 2014 ABSTRACT Purpose: Evaluation of computer based color deficiency test. Materials and Methods: Two hundred and sixty seven volunteers have been checked using both traditional Ishihara plates and a computer diagnosis program using LCD monitors. Results: The prevalence of red green color vision deficiency (RG-CVD) was 8.75% of male participants, no female participants were diagnosed, both in the paper based test, and in the computer based test. Computer based test gave 100% sensitivity and 98.78% specificity. -
COLOUR11. Phenomenology
In a center- surround cell of any kind, you have two receptive fields, one the small center region, the other the surround region. In a chromatic center-surround field, each in innervated by one class of receptor, and — their signals are antagonistic + _ — If you took the input — + from 2 different cones, each with the same receptive field, and connected them to single neuron, you would have a neuron that signaled wavelength contrast (but not across any space.) — + — + _ — With a blue light in the surround, the surround provides inhibition. 100% blue surround inhibition; no center excitation. Entire cell = No firing (-100%) — + _ — With a blue light in the center, there is no excitation. Entire cell = no change to base rate — + _ — With a sky blue light in the surround, the surround provides inhibition (55%). With the sky blue light in the center, the center provides 10 % excitation Entire cell = - 40% — + _ — If only the surround is illuminated, then the surround provides inhibition (30%) Entire Cell: -30%. — + _ — If only the center is illuminated, then the center is excited by 30%. Entire Cell: +30%. — + _ — 1:1 ratio of excitation The Null Point: if both the center and the surround were illuminated by light at this wavelength, there would be no change to the base firing rate of the cell. Entire cell = Base rate firing — + _ — With green light in the center; the center is excited (45%). There is no light on the surround; so the surround provides no inhibition. Entire cell = +45% — + _ — With green light in surround inhibits the surround 10% There is no light on the center; so the center provides no excitation.