GPS Safety Summary Naoh AI Version

Total Page:16

File Type:pdf, Size:1020Kb

GPS Safety Summary Naoh AI Version Technical information GPS Safety Summary Sodium Hydroxide (NaOH) This Product Safety Summary is intended to provide a general overview of the chemical substance in the context of ICCA Global Product Strategy. The information on the summary is basic information and is not intended to provide emergency response information, medical information or treatment information. Substance name Sodium hydroxide CAS-No. 1310-73-2 General statement Pure sodium hydroxide is a solid at room temperature and is generated from sodium chloride (common salt) by electrolysis. Sodium hydroxide is a hydrophilic alkaline substance (high pH) and therefore it is corrosive and hazardous to human health. It is most commonly found as a liquid, which has a concentration of between 20% and 50 % sodium hydroxide in water and is usually referred to as caustic soda liquor. The substance is used in large amounts in a variety of industries. Chemical identity Name Sodium hydroxide CAS number 1310-73-2 EC number 215-185-5 Molecular formula NaOH Synonyms caustic soda, caustic lye, lye (for water solution of sodium hydroxide) Evonik IIndustriesndustries AG | GPS Safety Summary | November 2011 | Version 1 | page 1/6 Uses and application Sodium hydroxide has many different functions and uses. For example, within industry it can be used to adjust the pH, to produce biodiesel from vegetable oils, to clean food processing equipment and bottles, to de-ink water (pulp and paper industry), to dry air, to absorb CO 2 from gases, to extract alumina (aluminium industry), to remove grease and paint from metal, to mercerize cotton (textile industry), to peel leather, to peel vegetables, to make pretzels, to manufacture chemicals (intermediate use), to regenerate resins or to soften water. Consumer uses include paint stripping or drain cleaning. Physical/chemical properproperttttiesiesiesies Pure sodium hydroxide is a solid at room temperature, though it is often sold as a liquid (aqueous solution). The appearance of the substance and some physicochemical properties are mentioned in the table below. Property Value Physical state solid Color white Density 2.1 g/cm 3 (20 °C) (fused solid) Melting/boiling point 323 °C/1388 °C Molecular weight 40.0 g/mol Sodium hydroxide is a strong alkaline substance that dissociates completely in water into the sodium ion (Na +) and hydroxide ion (OH -). The dissolution/dissociation in water is strongly exothermic (releases heat), so a vigorous reaction occurs when sodium hydroxide is added to water. The vapour pressure of the substance is very low and the melting point is high. Sodium hydroxide solutions attack aluminium and its alloys, giving off hydrogen gas. It can be neutralised with acids (e.g. hydrochloric acid) giving the sodium salts of the acids, which are usually pH neutral and non- corrosive. Health effects Sodium hydroxide is a strongly alkaline hydrophilic substance and therefore solid sodium hydroxide is highly corrosive. It reacts with greases and fats, which can lead to irreversible damage to any site of contact with the body (for example skin or eyes). Depending on the concentration, solutions of sodium hydroxide in water are corrosive, irritating or non-irritating and they cause direct local effects at the site of contact with the body. Because of the corrosive properties of sodium hydroxide, a high uptake via the mouth can be fatal. When a very large part of the skin is exposed to sodium hydroxide, it can also result in death. Sodium hydroxide does not cause skin allergies. Evonik IIndustriesndustries GmbH | GPS Safety SummarySummary| November 2010 page 2/6 Under normal conditions of handling and use of sodium hydroxide, when exposure is limited to low, non-irritating concentrations, the substance will dissociate into its constituent ions and will not be systemically available in the body. As a consequence, sodium hydroxide will not cause systemic toxicity in any organs, including the reproductive system. Furthermore, sodium hydroxide is not carcinogenic or genotoxic. Environmental effects The hazard of sodium hydroxide for the environment is caused by the hydroxide ion (pH effect). A high concentration in water will result in toxic effects for aquatic organisms e.g. fish. However, a low concentration in water will not result in effects on aquatic organisms because the sodium hydroxide will be neutralized by other substances present in water (for example dissolved carbon dioxide, organic acids) and thus the pH will not increase. Because sodium hydroxide is neutralized in the environment, the substance is not persistent and it will not accumulate in organisms or in the food chain. Bioaccumulation will not occur. Exposure Consumer Sodium hydroxide is used in consumer products. It can be used, for example, in floor stripping products, wood stripping products, hair straightening agents, oven cleaners, drain cleaners or other cleaning products. It is also used in very small amounts in food products to adjust pH or as an additive (E524). This use poses no risk to consumers. Many different consumer products containing sodium hydroxide may be available. The instructions on the label of these products should be read and followed carefully to ensure safe use. Direct skin contact with products or solutions containing a low concentration of sodium hydroxide ( < 0.5% in water) is not a concern for human health because, at low concentrations, the substance is not irritating or corrosive. No other adverse effects on human health are expected to occur. Direct contact with products or solutions containing high concentrations of sodium hydroxide (>2% in water) should be prevented, because of the corrosive effects. Worker Because sodium hydroxide has many different functions and uses, it is extensively used in the industry and also by other professionals. As mentioned above in the section on consumer exposure, skin contact for products or solutions with a low sodium hydroxide concentration is not a concern for human health because, at low concentrations, the substance is not irritating or corrosive (<0.5% in water). The sodium hydroxide which is manufactured and used in industry applications is usually corrosive and therefore automated and closed systems are used to prevent direct contact. In such situations, exposure to the Evonik IIndustriesndustries AG | GPS Safety Summary | November 2010 | Version 1 | page 3/6 substance for workers is very low. When exposure to an irritating or corrosive product could occur, appropriate personal protective equipment should be used. Workers should consult the manufacturer’s Safety Data Sheet to obtain specific advice. Environment The hazard of sodium hydroxide for the environment is caused by the hydroxide ion (pH effect). Because there is legislation for the pH control of waste water and surface water in many countries, a significant pH increase of the aquatic environment (e.g. a river or a sea) is not expected due to the manufacture or use of sodium hydroxide. Furthermore it is relatively easy to adapt the pH of waste water (to neutralise sodium hydroxide in the water) and therefore significant effects of sodium hydroxide on the aquatic environment are not expected. Emissions to air are also not a concern because sodium hydroxide will be rapidly neutralised in air due the presence of carbon dioxide in air. State agency review The substance was reviewed in 2002 under the OECD (Organisation for Economic Co-operation and Development) high production volume (HPV) chemicals program. This is a global program to evaluate the hazards of chemicals. In 2007 a European Union Risk Assessment Report was published for sodium hydroxide which was prepared in the context of Regulation 793/93 on the evaluation and control of the risks of existing substances. In 2010 sodium hydroxide has been registered under the European Union REACH Regulation EC/1907/2006 and the substance was found to be safe for the uses identified. The results of all these 3 regulatory programs are available via internet. • EU REACH registration number: 01-2119457892-27-0045 Regulatory information/classification and labelling The substance is subject to harmonised classification and labelling under the EU Classification Labelling and Packaging (CLP) Regulation EC/1272/2008. The main elements are given hereafter: GHSGHS----LabelingLabeling Skin corrosion category H314 Causes severe skin burns 1A and eye damage The hazard statement “causes severe skin burns and eye damage” is applicable for a concentration in chemical products of 2 % w/w or higher. Evonik IIndustriesndustries AG | GPS Safety Summary | November 2010 | Version 1 | page 4/6 For concentrations in products between 0.5 and 2 % the following hazard statements are applicable: - Causes skin irritation (H315) and - Causes serious eye irritation (H319). The European industry has decided to classify sodium hydroxide as corrosive to metals in the EU (H290; May be corrosive to metals). Conclusion Sodium hydroxide is used in large amounts in industry and consumer products. Due to the alkaline properties sodium hydroxide is corrosive at high concentrations. Direct contacts with these products should be prevented. However, no effects on human health are expected when humans are in contact with non-corrosive and non-irritating concentrations of the substance. The substance is neutralised in the environment and therefore it is not persistent. Furthermore it does not accumulate in organisms. Waste water which contains sodium hydroxide should be neutralised (pH control) before it is discharged to the environment.
Recommended publications
  • Liquid Lye MSDS
    MATERIAL SAFETY DATA SHEET LIQUID LYE Revision Number 4, Revision Date 10.01.29 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKING Product Code CON151BT Product Name LIQUID LYE Synonyms Liquid Sodium Hydroxide (50%) Manufacturer and Supplier CHEM CLEAN LTD #1 Trincity Drive Trincity Industrial Estate Trincity Trinidad and Tobago EMERGENCY TELEPHONE NUMBER (868) 662-2615 2. COMPOSITION/INFORMATION ON INGREDIENTS CAS CHEMICAL NAME % WEIGHT 1310-73-2 Sodium Hydroxide 49 min 3. HAZARDS IDENTIFICATION Emergency Overview: ♦ Corrosive ♦ Based upon available toxicity information for this and closely related materials, it is anticipated that this material will be harmful if ingested and can cause serious tissue damage Eye Contact ♦ Causes severe burns Skin Contact ♦ Causes severe irritation and chemical burns Inhalation ♦ None, if used in adequately ventilated area Ingestion ♦ Harmful if swallowed ♦ Causes serious damage to tissues General Advice ♦ See First Aid Section Properties affecting Health Principle Routes of ♦ Eye Exposure ♦ Skin 4. FIRST AID MEASURES General Advice ♦ Show this Safety Data Sheet to the Doctor in attendance Page 1 of 6 LIQUID LYE Skin Contact ♦ Immediately apply vinegar if readily available ♦ Immediately flush skin with plenty of cool running water for at least 15 minutes ♦ Immediately remove contaminated clothing ♦ Immediate Medical Attention is required if irritation persists or burns develop Eye Contact ♦ In case of eye contact, remove contact lens and rinse immediately with plenty of water,
    [Show full text]
  • (Oxy)Hydroxide Electrocatalysts for Water Oxidation Bryan R
    www.acsami.org Research Article Effect of Selenium Content on Nickel Sulfoselenide-Derived Nickel (Oxy)hydroxide Electrocatalysts for Water Oxidation Bryan R. Wygant, Anna H. Poterek, James N. Burrow, and C. Buddie Mullins* Cite This: ACS Appl. Mater. Interfaces 2020, 12, 20366−20375 Read Online ACCESS Metrics & More Article Recommendations *sı Supporting Information ABSTRACT: An efficient and inexpensive electrocatalyst for the oxygen evolution reaction (OER) must be found in order to improve the viability of hydrogen fuel production via water electrolysis. Recent work has indicated that nickel chalcogenide materials show promise as electrocatalysts for this reaction and that their performance can be further enhanced with the generation of ternary, bimetallic chalcogenides (i.e., Ni1−aMaX2); however, relatively few studies have investigated ternary chalcogenides created through the addition of a second chalcogen (i.e., NiX2−aYa). To address this, we fi studied a series of Se-modi ed Ni3S2 composites for use as OER electrocatalysts in alkaline solution. We found that the addition of Se results in the creation of Ni3S2/NiSe composites composed of cross-doped metal chalcogenides and show that the addition of 10% Se reduces the overpotential required to reach a current density of 10 mA/cm2 by 40 mV versus a pure nickel sulfide material. Chemical analysis of the composites’ surfaces shows a reduction in the amount of nickel oxide species with Se incorporation, which is supported by transmission electron microscopy; this reduction is correlated with a decrease in the OER overpotentials measured for these samples. Together, our results suggest that the incorporation of Se into Ni3S2 creates a more conductive material with a less-oxidized surface that is more electrocatalytically active and resistant to further oxidation.
    [Show full text]
  • 162 Part 175—Indirect Food Addi
    § 174.6 21 CFR Ch. I (4–1–19 Edition) (c) The existence in this subchapter B Subpart B—Substances for Use Only as of a regulation prescribing safe condi- Components of Adhesives tions for the use of a substance as an Sec. article or component of articles that 175.105 Adhesives. contact food shall not be construed as 175.125 Pressure-sensitive adhesives. implying that such substance may be safely used as a direct additive in food. Subpart C—Substances for Use as (d) Substances that under conditions Components of Coatings of good manufacturing practice may be 175.210 Acrylate ester copolymer coating. safely used as components of articles 175.230 Hot-melt strippable food coatings. that contact food include the fol- 175.250 Paraffin (synthetic). lowing, subject to any prescribed limi- 175.260 Partial phosphoric acid esters of pol- yester resins. tations: 175.270 Poly(vinyl fluoride) resins. (1) Substances generally recognized 175.300 Resinous and polymeric coatings. as safe in or on food. 175.320 Resinous and polymeric coatings for (2) Substances generally recognized polyolefin films. as safe for their intended use in food 175.350 Vinyl acetate/crotonic acid copoly- mer. packaging. 175.360 Vinylidene chloride copolymer coat- (3) Substances used in accordance ings for nylon film. with a prior sanction or approval. 175.365 Vinylidene chloride copolymer coat- (4) Substances permitted for use by ings for polycarbonate film. 175.380 Xylene-formaldehyde resins con- regulations in this part and parts 175, densed with 4,4′-isopropylidenediphenol- 176, 177, 178 and § 179.45 of this chapter.
    [Show full text]
  • The Influence of Sodium Hydroxide Concentration on the Phase, Morphology and Agglomeration of Cobalt Oxide Nanoparticles and Application As Fenton Catalyst
    Digest Journal of Nanomaterials and Biostructures Vol.14, No.4, October-December 2019, p. 1131-1137 THE INFLUENCE OF SODIUM HYDROXIDE CONCENTRATION ON THE PHASE, MORPHOLOGY AND AGGLOMERATION OF COBALT OXIDE NANOPARTICLES AND APPLICATION AS FENTON CATALYST E. L. VILJOENa,*, P. M. THABEDEa, M. J. MOLOTOa, K. P. MUBIAYIb, B. W. DIKIZAa aDepartment of Chemistry, Vaal University of Technology Private, Bag X021, Vanderbijlpark 1900, South Africa bSchool of Chemistry, University of the Witwatersrand, 1 Jan Smuts Avenue, Braamfontein Johannesburg 2000, South Africa The concentration of NaOH was varied from 0.2 M to 0.7 M during the preparation of the cobalt oxide/cobalt oxide hydroxide nanoparticles by precipitation and air oxidation. Cubic shaped and less well defined Co3O4 nanoparticles formed at 0.2 M NaOH. An increase in the NaOH concentration increased the number of well-defined cubic shaped nanoparticles. Agglomerated CoO(OH) particles with different shapes formed at the highest NaOH concentration. The cubic shaped Co3O4 nanoparticles were subsequently used as catalyst for the Fenton degradation of methylene blue and it was found that the least agglomerated nanoparticles were the most catalytically active. (Received June 25, 2019; Accepted December 6, 2019) Keywords: Cobalt oxide, Nanoparticles, Precipitation, pH, Fenton reaction 1. Introduction Controlling the size and the shape of nanoparticles using simple, inexpensive precipitation methods without sophisticated capping molecules, remains a challenge. Literature has indicated that the concentration of the base (pH) is an important parameter to control the size, shape and phase of metal oxide nanoparticles. Obodo et al.[1] used chemical bath deposition at atmospheric pressure and 70 °C to precipitate Co3O4 crystallites on a glass substrate and they showed that the crystallite sizes were larger at a higher pH of 12 in comparison to when a pH of 10 was used.
    [Show full text]
  • SODIUM HYDROXIDE @Lye, Limewater, Lyewater@
    Oregon Department of Human Services Office of Environmental Public Health (503) 731-4030 Emergency 800 NE Oregon Street #604 (971) 673-0405 Portland, OR 97232-2162 (971) 673-0457 FAX (971) 673-0372 TTY-Nonvoice TECHNICAL BULLETIN HEALTH EFFECTS INFORMATION Prepared by: ENVIRONMENTAL TOXICOLOGY SECTION OCTOBER, 1998 SODIUM HYDROXIDE @Lye, limewater, lyewater@ For More Information Contact: Environmental Toxicology Section (971) 673-0440 Drinking Water Section (971) 673-0405 Technical Bulletin - Health Effects Information Sodium Hydroxide Page 2 SYNONYMS: Caustic soda, sodium hydrate, soda lye, lye, natrium hydroxide CHEMICAL AND PHYSICAL PROPERTIES: - Molecular Formula: NaOH - White solid, crystals or powder, will draw moisture from the air and become damp on exposure - Odorless, flat, sweetish flavor - Pure solid material or concentrated solutions are extremely caustic, immediately injurious to skin, eyes and respiratory system WHERE DOES IT COME FROM? Sodium hydroxide is extracted from seawater or other brines by industrial processes. WHAT ARE THE PRINCIPLE USES OF SODIUM HYDROXIDE? Sodium hydroxide is an ingredient of many household products used for cleaning and disinfecting, in many cosmetic products such as mouth washes, tooth paste and lotions, and in food and beverage production for adjustment of pH and as a stabilizer. In its concentrated form (lye) it is used as a household drain cleaner because of its ability to dissolve organic solids. It is also used in many industries including glassmaking, paper manufacturing and mining. It is used widely in medications, for regulation of acidity. Sodium hydroxide may be used to counteract acidity in swimming pool water, or in drinking water. IS SODIUM HYDROXIDE NATURALLY PRESENT IN DRINKING WATER? Yes, because sodium and hydroxide ions are common natural mineral substances, they are present in many natural soils, in groundwater, in plants and in animal tissues.
    [Show full text]
  • Carbon Dioxide Capture from Atmospheric Air Using Sodium
    Environ. Sci. Technol. 2008, 42, 2728–2735 Carbon Dioxide Capture from Nearly all current research on CCS focuses on capturing CO2 from large, stationary sources such as power plants. Atmospheric Air Using Sodium Such plans usually entail separating CO2 from flue gas, compressing it, and transporting it via pipeline to be Hydroxide Spray sequestered underground. In contrast, the system described in this paper captures CO2 directly from ambient air (“air § capture”). This strategy will be expensive compared to capture JOSHUAH K. STOLAROFF, from point sources, but may nevertheless act as an important DAVID W. KEITH,‡ AND complement, since CO emissions from any sector can be GREGORY V. LOWRY*,† 2 captured, including emissions from diffuse sources such as Chemical and Petroleum Engineering, University of Calgary, aircraft or automobiles, where on-board carbon capture is and Departments of Civil and Environmental Engineering very difficult and the cost of alternatives is high. Additionally, and Engineering and Public Policy, Carnegie Mellon in a future economy with low carbon emissions, air capture University, Pittsburgh, Pennsylvania 15213 might be deployed to generate negative net emissions (1). This ability to reduce atmospheric CO2 concentrations faster Received October 15, 2007. Revised manuscript received than natural cycles allow would be particularly desirable in February 05, 2008. Accepted February 06, 2008. scenarios where climate sensitivity is on the high end of what is expected, resulting in unacceptable shifts in land usability and stress to ecosystems. In contrast to conventional carbon capture systems for Previous research has shown that air capture is theoreti- cally feasible in terms of thermodynamic energy require- power plants and other large point sources, the system described ments, land use (2), and local atmospheric transport of CO2 in this paper captures CO2 directly from ambient air.
    [Show full text]
  • Salts of Therapeutic Agents: Chemical, Physicochemical, and Biological Considerations
    molecules Review Salts of Therapeutic Agents: Chemical, Physicochemical, and Biological Considerations Deepak Gupta 1, Deepak Bhatia 2 ID , Vivek Dave 3 ID , Vijaykumar Sutariya 4 and Sheeba Varghese Gupta 4,* 1 Department of Pharmaceutical Sciences, School of Pharmacy, Lake Erie College of Osteopathic Medicine, Bradenton, FL 34211, USA; [email protected] 2 ICPH Fairfax Bernard J. Dunn School of Pharmacy, Shenandoah University, Fairfax, VA 22031, USA; [email protected] 3 Wegmans School of Pharmacy, St. John Fisher College, Rochester, NY 14618, USA; [email protected] 4 Department of Pharmaceutical Sciences, USF College of Pharmacy, Tampa, FL 33612, USA; [email protected] * Correspondence: [email protected]; Tel.: +01-813-974-2635 Academic Editor: Peter Wipf Received: 7 June 2018; Accepted: 13 July 2018; Published: 14 July 2018 Abstract: The physicochemical and biological properties of active pharmaceutical ingredients (APIs) are greatly affected by their salt forms. The choice of a particular salt formulation is based on numerous factors such as API chemistry, intended dosage form, pharmacokinetics, and pharmacodynamics. The appropriate salt can improve the overall therapeutic and pharmaceutical effects of an API. However, the incorrect salt form can have the opposite effect, and can be quite detrimental for overall drug development. This review summarizes several criteria for choosing the appropriate salt forms, along with the effects of salt forms on the pharmaceutical properties of APIs. In addition to a comprehensive review of the selection criteria, this review also gives a brief historic perspective of the salt selection processes. Keywords: chemistry; salt; water solubility; routes of administration; physicochemical; stability; degradation 1.
    [Show full text]
  • SALTS of FATTY ACIDS
    SALTS of FATTY ACIDS Prepared at the 33rd JECFA (1988), published in FNP 38 (1988) and in FNP 52 (1992). Metals and arsenic specifications revised at the 55th JECFA (2000). An ADI 'not specified' was established at the 33rd JECFA (1988) SYNONYMS INS No. 470 DEFINITION These products consist of calcium, potassium or sodium salts of commercial myristic, oleic, palmitic, stearic, acids or mixtures of these acids from edible fats and oils. The article of commerce can be further specified by: - saponification value, - solidification point for the fatty acids obtained from the salts, - iodine value, - residue on ignition including assay of the cation, and - moisture content Assay Not less than 95% total fatty acid salts, dry weight basis DESCRIPTION Hard, white or faintly yellowish, somewhat glossy and crystalline solids or semi-solids or white or yellowish-white powder FUNCTIONAL USES Anticaking agent, emulsifier CHARACTERISTICS IDENTIFICATION Solubility (Vol. 4) Potassium and sodium salts are soluble in water and ethanol; calcium salts are insoluble in water, ethanol and ether Test for cations Heat 1 g of the sample with a mixture of 25 ml of water and 5 ml of hydrochloric acid. Fatty acids are liberated, floating as a solid or oil layer on the surface which is soluble in hexane. After cooling, aqueous layer is decanted and evaporated to dryness. Dissolve the residue in water and test for the appropriate cation. Fatty acid composition Using the Method of Assay, identify the individual fatty sample. The fatty acid(s) in primary abundance should conform to those declared on the label of the product PURITY Free fatty acids Not more than 3% Measure free fatty acids as directed in the method Free Fatty Acids.
    [Show full text]
  • Exposure to Potassium Hydroxide Can Cause Headache, Eye Contact Dizziness, Nausea and Vomiting
    Right to Know Hazardous Substance Fact Sheet Common Name: POTASSIUM HYDROXIDE Synonyms: Caustic Potash; Lye; Potassium Hydrate CAS Number: 1310-58-3 Chemical Name: Potassium Hydroxide (KOH) RTK Substance Number: 1571 Date: May 2001 Revision: January 2010 DOT Number: UN 1813 Description and Use EMERGENCY RESPONDERS >>>> SEE LAST PAGE Potassium Hydroxide is an odorless, white or slightly yellow, Hazard Summary flakey or lumpy solid which is often in a water solution. It is Hazard Rating NJDOH NFPA used in making soap, as an electrolyte in alkaline batteries and HEALTH - 3 in electroplating, lithography, and paint and varnish removers. FLAMMABILITY - 0 Liquid drain cleaners contain 25 to 36% of Potassium REACTIVITY - 1 Hydroxide. CORROSIVE POISONOUS GASES ARE PRODUCED IN FIRE DOES NOT BURN Reasons for Citation Hazard Rating Key: 0=minimal; 1=slight; 2=moderate; 3=serious; f Potassium Hydroxide is on the Right to Know Hazardous 4=severe Substance List because it is cited by ACGIH, DOT, NIOSH, NFPA and EPA. f Potassium Hydroxide can affect you when inhaled and by f This chemical is on the Special Health Hazard Substance passing through the skin. List. f Potassium Hydroxide is a HIGHLY CORROSIVE CHEMICAL and contact can severely irritate and burn the skin and eyes leading to eye damage. f Contact can irritate the nose and throat. f Inhaling Potassium Hydroxide can irritate the lungs. SEE GLOSSARY ON PAGE 5. Higher exposures may cause a build-up of fluid in the lungs (pulmonary edema), a medical emergency. FIRST AID f Exposure to Potassium Hydroxide can cause headache, Eye Contact dizziness, nausea and vomiting.
    [Show full text]
  • Aluminium Distearate, Aluminium Hydroxide Acetate, Aluminium Phosphate and Aluminium Tristearate
    The European Agency for the Evaluation of Medicinal Products Veterinary Medicines Evaluation Unit EMEA/MRL/393/98-FINAL April 1998 COMMITTEE FOR VETERINARY MEDICINAL PRODUCTS ALUMINIUM DISTEARATE, ALUMINIUM HYDROXIDE ACETATE, ALUMINIUM PHOSPHATE AND ALUMINIUM TRISTEARATE SUMMARY REPORT 1. Aluminium is an ubiquitous element in the environment. It is present in varying concentrations in living organisms and in foods. Aluminium compounds are widely used in veterinary and human medicine. Other uses are as an analytical reagent, food additives (e.g. sodium aluminium phosphate as anticaking agent) and in cosmetic preparations (aluminium chloride). Aluminium distearate is used for thickening lubricating oils. Aluminium hydroxide acetate and phosphate are antacids with common indications in veterinary medicine: gastric hyperacidity, peptic ulcer, gastritis and reflux esophagitis. A major use of antacids in veterinary medicine is in treatment and prevention of ruminal acidosis from grain overload, adsorbent and antidiarrheal. The dosage of aluminium hydroxide is 30 g/animal in cattle and 2 g/animal in calves and foals. Gel preparations contain approximately 4% aluminium hydroxide. Aluminium potassium sulphate is used topically as a antiseptic, astringent (i.e. washes, powders, and ‘leg tighteners’ for horses (30 to 60 g/animal) and antimycotic (1% solution for dipping or spraying sheeps with dermatophilus mycotic dermatitis). In cattle it is occasionally used for stomatitis and vaginal and intrauterine therapy at doses of 30 to 500 g/animal. In human medicine, aluminium hydroxide-based preparations have a widespread use in gastroenterology as antacids (doses of about 1 g/person orally) and as phosphate binders (doses of about 0.8 g/person orally) in patients an impairment of renal function.
    [Show full text]
  • Chemical Compatibility Guide
    APPENDIX E CHEMICAL COMPATIBILITY GUIDE DISCLAIMER: This chart is intended to provide general guidance on chemical compatibility and should not be used for product selection. The chart is based on industry data and may not be applicable to your specific applications. Temperature, fluid concentration and other process conditions may affect the material compatibility. If there is uncertainty about the suitability of the material with the process chemical, Macnaught recommends physical testing of the sample material with the chemical. If further assistance is required, Macnaught's Technical Support Team can provide advice to assist with selection. S Recommended S E E L L RI Data not available RI E E E — E E E S S ST ST 61 Not recommended 61 0 0 S S 6 6 S S E E M M N N L L O O N N I I T T N N A A Y Y O O T T R R N N M M B B S S E E O O S S R R M M UMINIU UMINIU F F 6 6 T T A A K K 1 1 AL PP AL PP C VI PT F C VI PT F 3 3 Acetaldehyde — Aluminum Chloride 20% — — Acetamide — Aluminum Fluoride — — — Acetate Solvent — — — Aluminum Hydroxide — — Acetic Acid — — — Aluminum Nitrate — — — Aluminum Potassium Acetic Acid 20% Sulfate 10% — — — — Acetic Acid 80% — — — Aluminum Sulfate — Acetic Acid, Glacial — — Alums — — — — — Acetic Anhydride — Amines — — — — Acetone — Ammonia 10% — — Acetyl Chloride (dry) — — Ammonia Nitrate — — — — — Acetylene Ammonia, anhydrous — — — Acrylonitrile — — — Ammonia, liquid — — — Adipic Acid — Ammonium Acetate — — — Alcohols: Amyl — — — — Ammonium Bifluoride — — — — Alcohols: Benzyl — — — — Ammonium Carbonate — — Alcohols:
    [Show full text]
  • Managing Soil Salinity Tony Provin and J.L
    E-60 3-12 Managing Soil Salinity Tony Provin and J.L. Pitt* f your soil has a high salinity content, the plants ing may cause salts to accumulate in both surface growing there will not be as vigorous as they would and underground waters. The surface runoff of these Ibe in normal soils. Seeds will germinate poorly, dissolved salts is what gives the salt content to our if at all, and the plants will grow slowly or become oceans and lakes. Fertilizers and organic amendments stunted. If the salinity concentration is high enough, also add salts to the soil. the plants will wilt and die, no matter how much you water them. Effects of salts on plants Routine soil testing can identify your soil’s salinity As soils become more saline, plants become unable levels and suggest measures you can take to correct to draw as much water from the soil. This is because the specific salinity problem in your soil. the plant roots contain varying concentrations of ions (salts) that create a natural flow of water from the soil Salinity and salt into the plant roots. The terms salt and salinity are often used inter- As the level of salinity in the soil nears that of the changeably, and sometimes incorrectly. A salt is sim- roots, however, water becomes less and less likely to ply an inorganic mineral that can dissolve in water. enter the root. In fact, when the soil salinity levels are Many people associate salt with sodium chloride— high enough, the water in the roots is pulled back into common table salt.
    [Show full text]