. Attachment 5: OHMTADS

File 2; Entry 1; Accession No. 8300235 (CAS) CAS Registry Number: QSOOOOO1-O5Q8-O9 (MAT) Material Name: $$$ COAL TAR CREOSOTE $$$ (SYN) Synonyms: CREOSOTE (SEE ALSO WOOD CREOSOTE, ACCESSION NUMBER 8400350); CREOSOTE FROM COAL TAR; CREOSOTE OIL (CHEMICAL ABSTRACTS SERVICE, " HOWEVER, HAS GIVEN THIS SUBSTANCE A SEPARATE REGISTRY NUMBER—61789-28- 4); DEAD OIL; LIQUID PITCH OIL; TAR OIL; BRICK OIL; COAL TAR CREOSOTE OIL; COAL TAR OIL; CREOSOTE, COAL TAR; CREOSOTE, FROM COAL TAR; CREOSOTUM; RTECS NO. GF8615000. (TRN) Tradename (Company): PRESERV-O-SOTE (CREOSOTE OIL) (CROWLEY TAR PRODUCTS COMPANY, INC.). (CHMCY* 0001) .(FML) Chemical Formula: (UNSPECIFIED FORMULA) (SPC) Species in Mixture: COAL TAR CREOSOTE IS A DISTILLATE OF COAL TAR PRODUCED BY HIGH-TEMPERATURE CARBONIZATION OF BITUMINOUS COAL. (MEIEDD 0001) PROPERTIES VARY DEPENDING ON THE SOURCE OF THE TAR. AN IN-DEPTH REVIEW OF THE CHARACTERIZATION OF WOOD-PRESERVING COAL-TAR CREOSOTE IS GIVEN IN (XAFLA7 0001) . COAL TAR CREOSOTE COMPRISES LIQUID AND SOLID AROMATIC HYDROCARBONS, UP TO 3% TAR ACIDS, AND TAR BASES. (MEIEDD 0001) MAJOR COMPONENTS OF CREOSOTE ARE POLYCYCLIC AROMATIC HYDROCARBONS, MOST WITH THREE OR MORE RINGS: NAPHTHALENE, 3.0%; 2-METHYLNAPHTHALENE, 1.2%; 1- METHYLNAPHTHALENE, 0.9%; BIPHENYL, 0.8%; DIMETHYLNAPHTHALENES, 2.0%; ACENAPHTHENE, 9.0%; DIBENZOFURAN, 5.0%; FLUORENE, 10.0%; METHYLFLUORENES, 3.0%; PHENANTHRENE, 21.0%; ANTHRACENE, 2.0%; CARBAZOLE, 2.0%; METHYLPHENANTHRENES, 3.0%; METHYLANTHRACENES, 4.0%; FLUORANTHENE, 10.0%; PYRENE, 8.5%; BENZOFLUORENES, 2.0%; CHRYSENE, 3.0%. TIMBER-TREATING COAL- TAR CREOSOTE IS PREPARED TO CONFORM TO THE DISTILLATION RANGE OF THE AMERICAN WOOD PRESERVERS SPECIFICATION Pl-78. (THIS STANDARD SPECIFIES THAT NO MORE THAN 2.0% OF NEW OR USED CREOSOTE SHOULD DISTILL BELOW 210 DEGREES CELSIUS, THAT NO MORE THAN 12.0% SHOULD DISTILL BELOW 235 DEGREES CELSIUS, THAT 10.0 TO 35.0 PERCENT SHOULD DISTILL BELOW 270 DEGREES CELSIUS, THAT 40.0 TO 65.0 PERCENT SHOULD DISTILL BELOW 315 DEGREES CELSIUS, AND THAT 60.0 TO 77.0 PERCENT SHOULD DISTILL BELOW 355 DEGREES CELSIUS. ) IN ADDITION TO THE HYDROCARBONS LISTED ABOVE, CREOSOTE CONTAINS THE HETEROCYCLIC COMPOUNDS QUINOLINE, CARBAZOLE, AND DIBENZOFURAN. THE NITROGENOUS COMPOUNDS ARE THE "TAR BASES". COMPOUNDS BOILING FROM 200 TO 270 DEGREES CELSIUS ARE PRIMARILY NAPHTHALENES. THOSE BOILING BETWEEN 270 AND 355 DEGREES CELSIUS ARE A MIXTURE OF ACENAPHTHENE, FLUORENE, PHENANTHRENE, ANTHRACENE, AND OTHER HYDROCARBONS. THE FRACTION BOILING ABOVE 355 DEGREES CELSIUS CONTAINS PYRENE, FLUORANTHENE, AND CHRYSENE. (15SWA8 0002) (IDCDD* 0001) "CREOSOTES" OR "CREOSOTE OILS" ARE BLENDS OF A NUMBER OF RESIDUAL OILS FROM TAR DISTILLATION, SUCH AS NAPHTHALENE DRAIN OIL, WASH OIL, DRAINED ANTHRACENE OIL, AND HEAVY OIL. TIMBER PRESERVATION CREOSOTE IS A BLEND OF PRIMARILY WASH OIL, DRAINED ANTHRACENE OIL, AND HEAVY OIL. IF THE CREOSOTE IS TO BE USED FOR PARTIAL COMBUSTION TO CARBON BLACK, IT IS CHIEFLY A MIXTURE OF ANTHRACENE OIL AND HEAVY OIL. WINTER WASH OILS FOR DORMANT FRUIT TREES ARE CREOSOTES COMPRISING A MIXTURE OF DRAINED NAPHTHALENE OIL, WASH OIL, AND ANTHRACENE OIL CONTAINING RESIDUAL TAR ACIDS. CREOSOTE OILS CONTAIN MAINLY NAPHTHALENE, PHENOL, AND CRESOLS. PHENOLIC COMPOUNDS, INCLUDING NAPKTHOLS AND XYLENOLS, ARE THE "TAR ACIDS". (15SWA8 0002) (USS) Common Uses: COAL TAR CREOSOTE IS USED FOR IMPREGNATING WOOD (SUCH AS RAILROAD TIES, TELEPHONE POLES, AND MARINE PILINGS) TO PROTECT FROM ROT AND WORMS. (MEIEDD 0001) (CCDCDS 0002) OTHER USES INCLUDE WATERPROOFING AGENT, CONSTITUENT IN FUEL OIL, LUBRICANT FOR DIE MOLDS, PITCH FOR ROOFING, MANUFACTURE OF CHEMICALS AND LAMPBLACK. (85FFA3 0001) (PRD) Production Sites: U.S. STEEL CORPORATION, CLAIRTON WORKS, 400 STATE ST., P.O. BOX 270, CLAIRTON, ALLEGHENY COUNTY, PA, 15025, MID NO. 3293, EPA REGION 03; ALLIED CHEMICAL CORPORATION, P.O. BOX 1087R, MORRISTOWN, OOG003 NJ; CROWLEY TAR PRODUCTS COMPANY (CREOSOTE OIL), 261 MADISON AVE., NEW YORK, NY, NY 10016, (212)682-1200. (CHMCY* 0001) (BIN) Binary Reactants: COAL TAR CREOSOTE REACTS VIOLENTLY WITH CHLOROSULFONIC ACID. (DPMADX 0001) (LDL) Detection Limit (Lab.; Techniques, Ref) (ppm): CHEMICAL AND PHYSICAL METHODS FOR CHARACTERIZING WOOD-PRESERVING COAL TAR CREOSOTE ARE DESCRIBED IN (XAFLA7 195,1,174/NES). GAS CHROMATOGRAPHIC METHODS AND SPECTROPHOTOMETRIC METHODS REPORTED BEFORE 1974 ARE REVIEWED. A GC/MS METHOD FOR ANALYSIS OF CREOSOTE OIL HAS BEEN DESCRIBED IN A RUSSIAN PAPER BY DOLANSKY AND KOMORA IN SB. VYS. SK. CHEM.-TECHNOL. PRAZE, TECHNOL. PALIV, D30, 329-334 (1974). (CKABA8 0015) A VAPOR-PHASE ULTRAVIOLET ABSORPTION SPECTROSCOPIC METHOD AFTER EXTRACTION WITH HEXANE OR CHLOROFORM IS SAID TO BE SUITABLE FOR CREOSOTE IN WATER, BUT EXAMPLES ARE NOT GIVEN FOR THIS SUBSTANCE. (ANALAO 0006) ZITKO (1975) DEVELOPED A RAPID METHOD FOR SCREENING AQUATIC FAUNA FOR POLYCYCLIC AROMATIC HYDROCARBONS (PAH) TO DETECT CONTAMINATION BY CREOSOTE OIL. THE , CONTAMINANTS WERE SEPARATED FROM LIPIDS OF AQUATIC SPECIES BY COLUMN CHROMATOGRAPHY ON ALUMINA. THEN THEY WERE CHARACTERIZED AND QUANTITATED BY FLUOROMETRY WITH PYRENE AS A FLUORESCENCE STANDARD. THE DETECTION LIMIT FOR CREOSOTE WAS 100 .HU.G/G LIPID. (BECTA6 0038) AIR—BENZENE- SOLUBLE COMPOUNDS IN AIR. NIOSH METHOD NO. P&CAM 217. MATRIX: AIR PARTICIPATES TRAPPED ON SILVER MEMBRANE AND GLASS FIBER FILTERS. ULTRASONIC EXTRACTION WITH BENZENE, EVAPORATION OF ALIQUOT TO DRYNESS. WEIGH RESIDUE. DETECTION LIMIT: 20 .MU.G BENZENE-SOLUBLE MATERIAL IN A FILTER SAMPLE. WATER—A CREOSOTE-DERIVED PAH COMPLEX WAS DETERMINED BY BLACK (1982) BY HPLC WITH DETECTION BY ABSORBENCE AND FLUORESCENCE SPECTROPHOTOMETERS CONNECTED IN SERIES. (AECTCV 0013) THE AMERICAN SOCIETY FOR TESTING AND MATERIALS PROVIDES METHODS FOR ANALYZING AND TESTING CREOSOTE FOR WATER (METHOD D 370), HATTER INSOLUBLE IN BENZENE (D 367), SPECIFIC GRAVITY (D 368), DISTILLATION (D 246), SPECIFIC GRAVITY OF FRACTIONS (D 369), FLOAT TEST OR RESIDUE (D 139), AND COKE RESIDUE (D 168). (STDS** 0001) (STD) Standard Codes: SUPERFUND DESIGNATED (HAZARDOUS SUBSTANCES) LIST. HAZARDOUS WASTE NO. U051. HAZARDOUS WASTE NO. FOR THE WASTEWATER TREATMENT SLUDGES IN THE PRODUCTION OF CREOSOTE—K035. HAZARDOUS WASTE NO. FOR THE BOTTOM SEDIMENT SLUDGE FROM THE TREATMENT OF WASTEWATERS FROM WOOD PRESERVING PROCESSES THAT USE CREOSOTE AND/OR PENTACHLOROPHENOL— K001. COAL TAR CREOSOTE—STCC NO. 4915363. NFPA HAZARD CLASSIFICATION (CREOSOTE OIL) 2,2,0. NAS HAZARD RATING FOR BULK WATER TRANSPORTATION- CATEGORY (RATING): FIRE (1); HEALTH: VAPOR IRRITANT, (2); LIQUID OR SOLID IRRITANT, (3); POISONS, (2); WATER POLLUTION: HUMAN TOXICITY, (2); AQUATIC TOXICITY, (3); AESTHETIC EFFECT (4); REACTIVITY: OTHER CHEMICALS, (1); WATER, (0); SELF-REACTION, (0). U.S. COAST GUARD HAZARD ASSESSMENT CODE A-T-U-X-Y. (CGHCD* 0001) DOT—COAL TAR CREOSOTE OR CREOSOTE OIL— COMBUSTIBLE LIQUID. NA1993. NO LABEL REQUIREMENT. PACKAGING EXCEPTION 173.118A. NO SPECIFIC REQUIREMENT. NO PACKAGE LIMIT ON CARGO OR PASSENGER AIRCRAFT OR RAIL CAR. STOW ON OR UNDER DECK ON CARGO AND PASSENGER VESSELS. (FEREAC 0017) IMCO—NOT LISTED. SEE POISONOUS LIQUIDS, N.O.S. UNDER ICAO BELOW, THIS FIELD. IATA— LIQUID CREOSOTE. CLASS ORA.A. PACKING NOTE 692 FOR PASSENGER OR CARGO AIRCRAFT. NO LIMIT ON QUANTITY. (RARAD5 0002) ICAO—CREOSOTE IS SHIPPED ACCORDING TO SPECIFICATIONS FOR POISONOUS LIQUIDS NOT OTHERWISE SPECIFIED. UN NO. 2810. CLASS AND DIVISION 6.1. LABEL: "POISON" (GROUP I AND II) OR "KEEP AWAY FROM FOOD" (GROUP III). (ICAO** 0001) (FLM) Flammability: COAL TAR CREOSOTE WILL BURN. MAY BE IGNITED BY HEAT, SPARKS, AND FLAMES. FLAMMABLE VAPORS MAY SPREAD AWAY FROM SPILL. (85EWAF 0001) MODERATELY FLAMMABLE WHEN EXPOSED TO HEAT OR FLAME. (DPMADX 0001) (TCP) Toxic Combustion Products: NO DATA AVAILABLE ON COMBUSTION PRODUCTS. FIRE MAY PRODUCE IRRITATING OR POISONOUS GAS. (85EWAF 0001) (EXT) Extinguishing Method: COAL TAR CREOSOTE—SMALL FIRES: DRY CHEMICAL, 000004 CO2, WATER SPRAY OR ALCOHOL FOAM. LARGE FIRES: WATER SPRAY, FOG, OR ALCOHOL FOAM. MOVE CONTAINER FROM FIRE AREA IF YOU CAN DO IT WITHOUT ' RISK. STAY AWAY FROM ENDS OF TANKS. COOL CONTAINERS THAT ARE EXPOSED TO W FLAMES WITH WATER FROM THE SIDE UNTIL WELL AFTER FIRE IS OUT. FOR MASSIVE FIRE IN CARGO AREA, USE UNMANNED HOSE HOLDER OR MONITOR NOZZLES. WITHDRAW IMMEDIATELY IN CASE OF RISING SOUND FROM VENTING SAFETY DEVICE OR _ DISCOLORATION OF TANK. (85EWAF 0001) THE U.S. COAST GUARD (CGHCD* 0001) AND THE BUREAU OF EXPLOSIVES (BUXEH* 0001) STATE THAT SOLID STREAMS OF WATER MAY BE INEFFECTIVE. v (FLP) Flash Point (C.): 74 (DEGREES CELSIUS; COAL TAR CREOSOTE, CLOSED CUP *-' (CCDCDS 0002)) (AIP) Autoignition Point (C.): 336 (DEGREES CELSIUS; COAL TAR CREOSOTE l (CGHCD* 0001)) MEXP) Explosiveness: CONTAINER OF COAL TAR CREOSOTE MAY EXPLODE IN HEAT OF FIRE; VAPOR EXPLOSION HAZARD INDOORS, OUTDOORS, OR IN SEWERS. RUNOFF TO SEWER MAY CREATE FIRE OR EXPLOSION HAZARD. (85EWAF 0001) W(BLP) Boiling Point (C.): >180; 200 TO 400 (COAL TAR CREOSOTE); 200 TO 250; 200 TO 270 (CREOSOTE OILS) . (BOC) Boiling Characteristics: THE LOWER VALUE OF >180 DEGREES CELSIUS AND THE RANGE 200 TO 400 DEGREES CELSIUS ARE FOR COAL TAR CREOSOTE. (CGHCD* w 0001) CREOSOTE OILS (ALSO CAT.T.ED MIDDLE OILS) ARE GENERALLY THE FRACTION BOILING FROM APPROXIMATELY 200 TO 250 OR 270 DEGREES CELSIUS. (15SWA8 0002) w(SOL) Solubility (ppm @ 25C): 5 (SLC) Solubility Characteristics: COAL TAR CREOSOTE—5 PPM, INSOLUBLE (RCRAC* 80/EPA); VERY SLIGHTLY SOLUBLE (IDCDD* 0001); PRACTICALLY i, INSOLUBLE. (MEIEDD 0001) (SPG) Specific Gravity: 1.05 TO 1.09; 1.076 (COAL TAR CREOSOTE: 1.05 TO 1.09 AT 15 DEGREES CELSIUS (LIQUID); >=1.076 COAL TAR CREOSOTE AT 15 DEGREES CELSIUS) (CGHCD* 0001); (MEIEDD 0001) ^-(PER) Persistency: SLOWLY BIODEGRADABLE. (IDCDD* 0001) EPA ESTIMATED THAT FOR PONDS, LAKES, AND RESERVOIRS WITH AVERAGE RETENTION TIMES OF 100 OR i 365 DAYS, 98 TO 99% OF THE CREOSOTE EMITTED TO THE WATER BODY WILL BE w DEGRADED OR ELIMINATED. APPROXIMATELY 9.1% OF THE CREOSOTE EMITTED TO A RIVER WILL BE DISSOLVED AND TRANSPORTED 50 TO 250 MILES DOWNSTREAM WITH 5 DAYS* TRAVEL TIME. ABOUT 91% OF THE TOTAL AMOUNT EMITTED WILL BE DEGRADED OR OTHERWISE ELIMINATED. IN BOTH KINDS OF WATERBODIES, THE CREOSOTE *~ CONCENTRATION IN SEDIMENTS AND FISH WILL BE 0.2 AND 0.6, RESPECTIVELY, OF THE DISSOLVED CONCENTRATION. NO RELEASES TO THE ATMOSPHERE ARE EXPECTED. (RCRAC* 80/EPA) IN A REAL-WORLD CASE OF CONTAMINATION OF A RIVER BY ^- CREOSOTE FROM A POINT SOURCE, CONCENTRATIONS OF POLYCYCLIC AROMATIC HYDROCARBONS (PAH) IN THE RIVER REACH, CALCULATED ON THE BASIS OF THE AMOUNTS OF ORGANIC MATTER CONTAINED IN THE SEDIMENTS, DECLINED RAPIDLY ^_ BELOW THE POINT SOURCE. THE PATTERN OF DECREASE WAS READILY APPROXIMATED BY DOUBLE EXPONENTIAL EQUATIONS. CONCENTRATIONS TENDED TO BECOME ASYMPTOTIC, AND THE SEDIMENTS WERE CONTAMINATED OVER A CONSIDERABLE DISTANCE. THE INITIAL RAPID DECREASE HAY HAVE REFLECTED A DISBURSIVE- "- DILUTIONAL PROCESS. THE SLOWER PROCESS HAY HAVE BEEN DUE TO THE GRADUAL MINOR WEATHERING LOSSES OF THE LOWER-MOLECULAR-WEIGHT COMPOUNDS. (AECTCV 0013) COAL TAR CREOSOTE IS RELATIVELY IMMOBILE IN TERRESTRIAL SYSTEMS '— WHEN USED AS A WOOD PRESERVATIVE CHEMICAL. IN MICROCOSM TESTS WITH RADIOLABELED CREOSOTE, NO CONTAMINATION WAS FOUND IN THE GROUNDWATER OR : LEACHATE. RESIDUES FROM MICROCOSM SOIL IMMEDIATELY AROUND CREOSOTE- 1__, TREATED POSTS SHOWED NO DEGRADATION OF THE CARBON-14 LABELED ACENAPHTHENE OR PHENANTHRENE. (JAFCAU 0011) (PFA) Potential for Accumulation: IN THE EPA ESTIMATES DESCRIBED IN FIELD ; PER, THE BIOCONCENTRATION FACTOR IS 0.6 OF THE DISSOLVED CONCENTRATION IN w A WATER BODY. (RCRAC* 80/EPA) POLYCYCLIC AROMATIC HYDROCARBONS FROM CREOSOTE OIL WERE NOT DETECTABLE IN COMMERCIAL MARINE FISH (HERRING AND ; COD LIVER) AND SEAL OILS. CREOSOTE OIL WAS FOUND IN SHELLFISH LIPIDS IN 000005 '"" CONCENTRATIONS OF 1046 (MUSSELS), 3254 AND 459 (PERIWINKLES), 354 AND 202 (WHELKS), AND 459 PPM (CLAMS). (BECTA6 0038) LOBSTERS EXPOSED TO 0.3 PPM ; COAL TAR CREOSOTE IN SEAWATER SHOWED INCREASING CREOSOTE CONCENTRATION IN w- THE KEPATOPANCREAS WITH EXPOSURE TIME OF AT LEAST 120 HOURS. THE RATE WAS ABOUT 85 .MU.G/G LIPID/HOUR. HEP ATOPANCREASES OF LOBSTERS THAT DIED HAD 47,500 AND 23,700 .MU.G/G LIPID IN THE HEPATOPANCREAS. LOBSTERS WITH UP _ TO 10,850 .MU.G/G LIPID IN THE HEPATOPANCREAS WERE ALIVE AND APPARENTLY HEALTHY WHEN SAMPLED. (BECTA6 0040) IN A MICROCOSM EXPERIMENT, COAL TAR - CREOSOTE WAS MIXED WITH CARBON-14-LABELED PHENANTHRENE OR ANTHRACENE. THE GRAY-TAILED VOLE (MICROTUS CANICAUDUS), CRICKETS, SNAILS, EARTHWORMS, AND "" TENEBRIO ACCUMULATED MORE LABELED MATERIAL FROM CREOSOTE THAN FROM OTHER LABELED WOOD PRESERVATIVE CHEMICALS SUCH AS PENTACHLOROPHENOL. A HIGH CONCENTRATION OF CARBON-14 ACCUMULATED IN THE VOLE BRAIN FROM THE ^ PHENANTHRENE/CREOSOTE EXPERIMENT. PLANTS TOOK UP 2.7 TO 8.8 PPM OF THE LABELED PAH. (JAFCAU 0011) \ (TOO) Food Chain Contamination Potential: BASED ON A TERRESTRIAL MICROCOSM w EXPERIMENT, THE ECOLOGICAL MAGNIFICATION INDEX FOR CARBON-14-PHENANTHRENE- LABELED COAL TAR CREOSOTE WAS 12 AND WAS 31 FOR CARBON-14-ACENAPHTHENE- LABELED CREOSOTE. (JAFCAU 0011) ' (CAG) Carcinogenicity: LABORATORY ANIMALS—100% COAL TAR CREOSOTE APPLIED w THREE TIKES PER WEEK FOR 28 WEEKS GAVE SKIN CARCINOMAS IN 82%, TUMORS IN 92%; BUT IN ANOTHER STUDY LASTING FOR 70 WEEKS, SKIN TUMORS APPEARED IN - 50%. EXPOSURE TO 100% CREOSOTE TWICE A WEEK FOR 21 WEEKS GAVE SKIN AND ^- LUNG TUMORS IN 74% OF THE ANIMALS. EXPOSURE TO 20 TO 80% CREOSOTE THREE TIMES PER WEEK FOR 6 TO 44 WEEKS GAVE SKIN CARCINOMAS IN 88%, TUMORS IN , 100%. (NIOTR* 0001) HUMANS—SKIN CANCERS HAVE BEEN DESCRIBED AFTER HUMAN _ EXPOSURES TO CREOSOTE OIL. LIJINSKY ET AL. (1957) FOUND COMMERCIAL CREOSOTE OILS HIGHLY CARCINOGENIC. THE MOUSE CARCINOGENS BENZ[A]ANTHRACENE AND CHRYSENE WERE PRESENT AT CONCENTRATIONS OF 2750 PPM 1 AND 1270 PPM, RESPECTIVELY. (IMEMDT 0004) THE 1982 PESTICIDE REBUTTABLE w PRESUMPTION AGAINST REGISTRATION (RPAR) OF WOOD PRESERVATIVES REVIEWED THE HUMAN CASE AND ANIMAL STUDIES AND CONCLUDED THAT CREOSOTE EXPOSURE OF ; LONG DURATION AT HIGH LEVELS CONSTITUTES A HUMAN SKIN CANCER HAZARD SINCE w WHOLE CREOSOTE IS CLEARLY AN ANIMAL CARCINOGEN AND MANY OF THE INDIVIDUAL CHEMICALS IN CREOSOTE ARE CARCINOGENS AS WELL. (REBUT* 0002) IN A COMMUNITY EXPOSED TO LOW LEVELS OF CREOSOTE COMPONENTS IN THE MUNICIPAL DRINKING WATER (ST. LOUIS PARK), INCIDENCES OF CANCERS AT ALL SITES COMBINED AND BREAST CANCER WERE VERY SIGNIFICANTLY DIFFERENT FROM INCIDENCES IN NEARBY COMMUNITIES. (MIMDAL 0001) (HUT) Mutagenicity: THE 1982 REBUTTABLE PRESUMPTION AGAINST REGISTRATION *-' (RPAR) OF WOOD PRESERVATIVES CRITICALLY REVIEWS STUDIES OF THE MUTAGENICITY OF COAL TAR CREOSOTE IN BACTERIA (FRAMESHIFT MUTATION), MOUSE LYMPHOMA CELLS (WEAK WITHOUT METABOLIC ACTIVATION), AND DIPLOID _ HUMAN EMBRYONIC LUNG TISSUE (WEAK AT ACTION AT HIGH CONCENTRATIONS). EPA CONCLUDED THAT APPLICATION OF CREOSOTE WOOD PRESERVATIVES AND THE USE OF CREOSOTE-CONTAINING PRODUCTS POSES AN UNQUANTIFIABLE SIGNIFICANT RISK OF MUTAGENICITY TO THE HUMAN POPULATION. (REBUT* 0002) ^(FTB) Fresh Water Toxicity Text: . .Cone.I Expos I Specie I Effect (Test Environment (Reference I

0.99 96 BLUEGILL STATIC, 60:40 PAWPAG 0001 (LEPOMIS CREOSOTE-COAL TAR MACROCHIRUS) 0.88 it RAINBOW TROUT N M (SALMO GAIRDNERI) 3.72 24 BLUEGILL TL50 • 4.42 96 RAINBOW TROUT M H • 00000J 0.75 M BLUEGILL NO- « M *»•• EFFECT LEVEL : 0.49 M RAINBOW TROUT N N v- 3.51 24 GOLDFISH TL50 STATIC, MARINE M' (CARASSIUS CREOSOTE (AMERICAN AURATUS) WOOD PRESERVERS u ASSOCIATION 12VXA5 0001) M n k. 2.62 96 GOLDFISH 0.25 N N NO- N *"" EFFECT LEVEL 1 N M LETHARG >-' Y, LOSS OF w EQUILIB RIUH, „ RECOVER *' . Y ^ 2 . 1624 RAINBOW TROUT TL50 M N 0.56 96 n N n n v TO WO. 75 0.32 N M NO- EFFECT ^i LEVEL 2.91% 48 DAPHNIA PULEX LC50 STATIC EWSFN* 0001

^u, - WATE_ R SOLUB : LE w FRACT ION 1.8% n N LC30 ^ WATER SOLUB LE ^ FRACT ION 1.0% n N LC20 ^_ WATER : SOLUB /LE ** FRACT . ION 1.8% CHRONI n (SEE '—: WATER C BELOW) ; SOLUB *J LE FRACT ION ABOVE CAUSES IMPAIRMENT OF MOLT KG; INCREASED ABORTION RATES (HIGH NUMBER OF PARTIAL ABORTIONS); MARKED REDUCTION IN NUMBERS OF BROODS (NO MEAN LIVE YOUNG PER ANIMAL); HARKED GROWTH RATE REDUCTION; REDUCED SURVIVAL TIKE; INCREASED OXYGEN CONSUMPTION; DELAYED REPRODUCTIVE MATURATION. 000007 • 1.0% WATER ' SOLUB LE FRACT , ION ABOVE CAUSES IMPAIRMENT OF MOLTING; REDUCED NUMBERS OF BROODS; INCREASED ABORTION RATES (MORE FULL ABORTIONS AND MORE BROODS THAN FOR DAPHNIA TESTE WITH 1.8% WATER-SOLUBLE FRACTION); HIGH NUMBER OF DEAD YOUNG WITHOUT SPINES; MARKED GROWTH RATE REDUCTION; INCREASED MEAN FILTERING RATE. (STB) Salt Water Toxicity Text: Cone.I Expos (Specie (Effect (Test environment (Reference I |(Hr) | (I | | 0.02\96\LARVAL LOBSTERS (HOMARUS AMERICANUS)\20 DEGREES CELSIUS, AERATED SEA WATER\BECTA6 0040 1.76\96\ADULT LOBSTERS\10 DEGREES CELSIUS, AERATED SEA WATER\BECTA6 0040 0.13\96\CRANGON SEPTEMSPINOSA\10 DEGREES CELSIUS, AERATED SEA WATER\BECTA6 0040 0.11\96\10 DEGREES CELSIUS, AERATED SEA WATER\BECTA6 0040. (ATB) Animal Toxicity Text: Value|Time (Soecies |Param. (Route (Reference | (COAL RAT LD50 ORL CEHKP* 0001 TAR CREOS OTE) 1700 >7950 RET n SKN CEHKP* 0001. Livestock Toxicity (Reference): FREQUENT DOSES OF COAL TAR CREOSOTE IN CAPSULES TO THREE 300-POUND CALVES TOTALLING APPROXIMATELY ONE POUND OVER A TWO-MONTH PERIOD CAUSED NO APPARENT ILL EFFECTS IN THE CALVES. THERE WAS NO APPARENT ORGAN DAMAGE IN THE SACRIFICED CALF. (CEHKP* 0001) IN AN ANECDOTE, THE FEEDING OF CALVES OF ONE POUND OF CREOSOTE PER MONTH WAS REPORTED NOT TO HAVE AFFECTED THE FLAVOR OF THE MEAT. (PAWPAG 0001) (WAN) Acute Waterfowl Toxicity (ppm): 10388; 2150 (WAR) Acute Waterfowl Toxicity (Reference): EIGHT-DAY DIETARY LC50 FOR MALLARD DUCK (ANAS PLATYRHYNCHOS) OF 60:40 CREOSOTE-COAL TAR. THE VALUE FOR BOBWHITE QUAIL (COLINUS VIRGINIANUS) WAS 1261 PPM. 2150 PPM IN DIET FOR 8 DAYS WAS A NO-EFFECT LEVEL FOR MALLARD DUCKS FOR CREOSOTE-COAL TAR (60:40). SIMILARLY, 215 PPH WAS THE NO-EFFECT LEVEL FOR BOBWHITE QUAIL. THE BIRDS WERE REPELLED BY THE CREOSOTE AND FOOD INTAKE WAS REDUCED. (PAWPAG 0001) (TRT) Hajor Species Threatened: CRUSTACEANS. LARVAL LOBSTERS ARE MORE SENSITIVE THAN ADULTS. (BECTA6 0040) (INK) Inhalation limit (value): 0.1 (INT) Inhalation Limit (Text): THERE ARE NO THRESHOLD LIMIT VALUES FOR SPECIFIC POLYCYCLIC AROMATIC HYDROCARBONS. OSH PEL (TWA) FOR COAL TAR VOLATILES (BENZENE-SOLUBLE FRACTION) ANTHRACENE, BAP, PHENANTHRENE, ACRIDINE, CHRYSENE, PYRENE IS 0.2 HG/H3. OSHA CATEGORIZES PARTICULATE PAH'S AS HUMAN CARCINOGENS AND ESTABLISHED AN 8-HOUR TIME-WEIGHTED AVERAGE OF 150 .MU. G/M3 FOR COKE OVEN EMISSIONS. (29CFR* 1910) NIOSH RECOMMENDED A 10-HOUR TIME-WEIGHTED AVERAGE OF 0.1 MG/H3 FOR COAL TAR PRODUCTS SUCH AS COAL TAR, CREOSOTE, AND COAL TAR PITCH. (CRSOE* 78- 107,7/NIOSH) THE AMERICAN CONFERENCE OF GOVERNMENTAL INDUSTRIAL HYGIENISTS, ACGIK, RECOMMENDED AN 8-HOUR TIME-WEIGHTED AVERAGE OF 0.2 MG/M3 FOR THE BENZENE-SOLUBLE FRACTION OF COAL TAR PITCH OR VOLATILES. (DRC) Direct Contact: COAL TAR CREOSOTE—CHARACTERISTIC SHARP ODOR. (MEIEDD 0001) NAPHTHENIC ODOR. (CCDCDS 0002) SHARP, SMOKY SMELL AND CAUSTIC 000008 BURNING TASTE. (85FFA3 0001) VAPORS CAUSE MODERATE IRRITATION OF THE NOSE AND THROAT. LIQUID BURNS EYES SEVERELY (SEE BELOW) AND CAUSES REDDENING '|^ AND .ITCHING ON SKIN. FAIRLY SEVERE SKIN IRRITANT, CAUSING PAIN AND SECOND- DEGREE BURNS AFTER CONTACT FOR A FEW MINUTES. (CGHCD* 0001) CREOSOTE ACCORDING TO THE AMERICAN WOOD PRESERVERS ASSOCIATION Al SPECIFICATION i DOES NOT CONTAIN A LARGE AMOUNT OF CRESOLS. THE VAPOR FROM HEATED ~ CREOSOTE IRRITATES EYES AND RESPIRATORY TRACT. THE LIQUID IS A PRIMARY SKIN IRRITANT BUT IS NOT AN EYE IRRITANT BY THE FHSA ANIMAL TEST. \ PHOTOSENSITIZATION. FAIR-SKINNED WORKERS ARE SENSITIVE WHEREAS DARK- — SKINNED WORKERS ARE RESISTANT. (RVR29* 0001) OTHER SYMPTOMS OF SKIN AND MUCOUS MEMBRANE CONTACT WITH CREOSOTE LIQUID OR VAPOR CONDENSATE INCLUDE • GRAYISH YELLOW TO BRONZE PIGMENTATION, PAPULAR AND VESICULAR ERUPTIONS, t_, GANGRENE, AND CANCER. EYE INJURIES INCLUDE KERATITIS; CONJUNCTIVITIS; AND CORNEAL ABRASION, WHICH RESULTS IN PERMANENT CORNEAL SCARS IN ABOUT ONE- THIRD OF THE CASES. (14CYAT 0002) THE LATTER REFERENCE MAY BE TO THE EFFECTS OF CREOSOTES WITH HIGH PHENOLIC CONTENTS. W(JNS) General Sensation: CREOSOTE (UNSPECIFIED SOURCE)—ABDOMINAL PAIN, CONJUNCTIVITIS, CONVULSIONS, CYANOSIS, DIZZINESS, HEADACHE, NAUSEA AND VOMITING, PHOTOSENSITIZATION OF THE SKIN, SALIVATION. (85EUA9 0001) COAL w. TAR CREOSOTE—SYMPTOMS AFTER INGESTION INCLUDE SALIVATION, VOMITING, RESPIRATORY DIFFICULTIES, THREADY PULSE, DIZZINESS, HEADACHE, LOSS OF , PUPILLARY REFLEXES, HYPOTHERMIA, CYANOSIS, AND MILD CONVULSIONS. (14CYAT .. 0002) (CGHCD* 0001) VAPORS HAY CAUSE SUFFOCATION. (85EWAF 0001) (DHR) Direct Human Ingestion (Reference): A DOSE OF HORE THAN ONE OUNCE TO ONE PINT OR ONE POUND WOULD PROBABLY BE LETHAL TO A 150-POUND HAN. (RVR29* 0001) AMOUNTS OF 7 G SWALLOWED BY ADULTS AND 1 OR 2 G BY CHILDREN ^ HAVE PROVED FATAL AFTER 14 TO 36 HOURS. (14CYAT 0002) (SAF) Personal Safety Precautions: AVOID BREATHING VAPORS. KEEP UPWIND. WEAR S PROTECTIVE BOOTS, PROTECTIVE GLOVES, AND GOGGLES; IF CONTACT WITH U» CREOSOTE IS ANTICIPATED, WEAR FULL PROTECTIVE CLOTHING. WASH AWAY ANY MATERIAL THAT HAY HAVE CONTACTED THE BODY OR EYES WITH COPIOUS AMOUNTS OF WATER OR SOAP AND WATER. (BUXEH* 0001) REMOVE AND ISOLATE CONTAMINATED CLOTHING AND SHOES. (CGHCD* 0001) (85EWAF 0001) USE ALL-SERVICE CANISTER '"" MASK, RUBBER GLOVES, CHEMICAL SAFETY GOGGLES AND/OR FACE SHIELD, OVERALLS OR A NEOPRENE APRON, BARRIER CREAMS. (CGHCD* 0001) WEAR PROTECTIVE \ CLOTHING IF EXPOSURE TO LIQUID OR HIGH VAPOR CONCENTRATION IS EXPECTED. ^ WEAR MASKS WITH FULL-FACE PROTECTION AND ORGANIC VAPOR CANISTERS. (85FFA3 0001) (AHL) Acute Hazard Level: SLIGHTLY TOXIC BY ORAL AND DERMAL ROUTES. (RVR29* w 0001) (ACT) Action Levels: KEEP SPARKS, FLAMES, AND OTHER SOURCES OF IGNITION AWAY. (BUXEH* 0001) STOP DISCHARGE IF POSSIBLE. CALL FIRE DEPARTMENT. NOTIFY LOCAL HEALTH AND POLLUTION CONTROL AGENCIES. NOTIFY LOCAL HEALTH w AND WILDLIFE OFFICIALS. NOTIFY OPERATORS OF NEARBY WATER INTAKES. (CGHCD* 0001) KEEP UNNECESSARY PEOPLE AWAY. ISOLATE FOR 0.5 MILE IN ALL DIRECTIONS IF TANK OR TANK CAR IS INVOLVED IN FIRE. (85EWAF 0001) — RESTRICT FARM USE AND INDUSTRIAL USE OF CONTAMINATED WATER. (CGRSP* 0001) (AML) In Situ Amelioration: SEEK PROFESSIONAL ASSISTANCE FROM EPA'S ENVIRONMENTAL RESPONSE TEAM (ERT), EDISON, NJ, 24-HOUR NUMBER (201)321- _ 6660. STOP LEAK IF YOU CAN DO IT WITHOUT RISK. (85EWAF 0001) IF NEEDED, PLUG THE LEAK WITH EXPANDABLE POLYURETHANE. SPILLS ON LAND—USE EARTHEN DIKES, EXCAVATION AND/OR DIKES, FOAMED POLYURETHANE OR FOAMED CONCRETE i (KZCSC* 0001) OR GELLING. ABSORPTION ON ACTIVATED CARBON (HZCSC* 0001), ^ SAWDUST, OR WOODCHIPS (SINCE WOOD ABSORBS). ABSORB ON CLAY, BENTONITE, FLY ASH TO BE DISPOSED OF BY LANDFILLING OR LAND-FARMING. SPILLS ON WATER BODY—IF THE CREOSOTE SINKS, USE DREDGING, TRENCHES (HZCSC* 0001) SINCE i~ CREOSOTE DOES NOT DISSOLVE AND SINKS IN WATER, USE PUMPING (CGRSP* 0001). BIODEGRADATION IS POSSIBLE IF SPILL VOLUME IS LOW RELATIVE TO STREAM VOLUME. IF THE CREOSOTE FLOATS, USE WEIRS, SKIMMING, OR BOOMING FOLLOWED BY CARBON ADSORPTION (HZCSC* 0001), OR BIODEGRADATION IF VOLUME IS LOW. 000009 WATER RUNOFF FROM FIRE PROTECTION SHOULD BE CONTAINED AND TREATED EITHER BY CARBON ADSORPTION OR BIOLOGICALLY. CHEMICAL OXIDATION WITH CHLORINE, • CHLORINE DIOXIDE, OR OZONE IS NOT RECOMMENDED BECAUSE THE REACTION *" PRODUCTS AND THEIR TOXICITIES HAVE NOT BEEN FULLY CHARACTERIZED. THOROUGHLY DRAIN EMPTY CONTAINERS BEFORE DISPOSAL. DO NOT RINSE WITH : WATER OR HYDROCARBON SOLVENT. (IDCDD* 0001) w(DIS) Disposal Methods: CARBON CONTAMINATED WITH CREOSOTE CAN BE REGENERATED AND DESORBED. CREOSOTE CAN BE DESTROYED IN AN RCRA-APPROVED INCINERATOR, i CEMENT KILN, OR BOILER. ALTERNATIVELY, THE CARBON, SAWDUST, OR WOOD CHIPS CAN BE DIRECTLY BURNED IN AN RCRA-APPROVED INCINERATOR. CREOSOTE- ~~ CONTAMINATED WATER CAN BE TREATED WITH CARBON AND THE CARBON CAN BE TREATED IN ANY OF THE ABOVE METHODS. BIODEGRADABILITY OF CREOSOTE IS LOW. ' (IDCDD* 0001) HENCE, THE WATER CAN BE TREATED IN BIOLOGICAL WASTEWATER w TREATMENT OR LANDFARMING. (RMRNR* 0010) (WAT) Major Water Use Threatened: DRINKING WATER. THE TASTE OF CREOSOTE IN : WATER IS DETECTABLE AT 0.125 PPB. (RCRAC* 80/EPA) v-(LOC) Probable Location and State of Material: COAL TAR CREOSOTE— TRANSLUCENT BLACK TO BROWN, OILY LIQUID HEAVIER THAN, AND PRACTICALLY INSOLUBLE IN, WATER. (MEIEDD 0001) YELLOWISH TO BROWN TO DARK GREEN ' ; COLORED LIQUID WITH A CHARACTERISTIC AROMATIC ODOR. (BUXEH* 0001) (CGHCD* 0001) IT IS SLIGHTLY HEAVIER AND DEPENDING ON COMPOSITION HAY SINK OR FLOAT ON WATER. AT ATMOSPHERIC TEMPERATURES, PART OF THE CREOSOTE - IS USUALLY CRYSTALLINE. (STDS** 0001) W(HOH) Water Chemistry: CREOSOTE DOES NOT REACT WITH WATER. THE PAHfS ARE OXIDIZED IN TYPICAL WATER TREATMENT PLANTS, BUT THE PRODUCTS HAVE NOT BEEN IDENTIFIED. CREOSOTE CONSTITUENTS HAY ALSO REACT PHOTOCHEMICALLY IN U SOLUTION. (IDCDD* 0001)

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