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Sinobiological Inc. Advantages SinoBiological Inc. Established in 2007, Sino Biological is a global biotechnology company manufacturing high quality research reagents for basic, translational, and clinical research. Sino Biological laboratories consist of over 80,000 square meters, producing cDNAs, recombinant proteins, antibodies and antibody-based kits that are used to study cellular function and human diseases. Sino Biological scientists are experienced in recombinant protein expression and purification from bacterial, yeast, insect and mammalian system. The scientists have also developed technologies to produce and purify a comprehensive collection of mouse monoclonal antibodies, rabbit polyclonal antibodies, and rabbit monoclonal antibodies. Sino Biological offers integrated service from gene cloning to protein expression, protein purification, and immunization for polyclonal or monoclonal antibody generation. We have provided CRO services to produce targets proteins, antibodies, and optimized ELISA tools to meet the needs of the biopharmaceutical industry, including the top 10 pharmaceutical companies. Sino Biological product sales are supported through a network of distributors in North American, European and Asian markets. We are proud that our products are helping scientists to solve significant problems in life science research. Every product has to pass rigorous QC test standards to ensure consistent high quality. We validate our product application and guarantee its performance as specified. We are developing tools and technologies to provide the global scientific community with the best-in-class product to accelerate scientific discovery and innovation. Advantages Best Monoclonal Antibody Tools Worldwide Maximum 200-Fold Enhanced ELISA sensitivity 5 pg-level Antigen Detection Limit in Western Blot Leading 2nd Generation Rabbit mAb Technology No Products From Origin Entrusted Manufacturer Centralized Protein & Antibody Expression Lab Worldwide 60+ Highly Centralized Cell Culture Bioreactors 7000+ Protein Bulks in Stock 2000+ New Products Released Per Year 30-100 Grams Custom-Tailored mAb Production in Weeks Leading Pre-Clinical CRO for Biologics Worldwide One-stop Service from Discovery to Production Record Speed from DNA to Purified mAbs Serving Top-10 global Pharmaceutical/Biotech Companies 2007 04 Founded in Beijing, China. 2008 First hundreds of recombinant proteins were released. 04 2009 Three recombinant protein and antibody production platforms were 04 constructed. Online sale was launched to worldwide customers. 10 The Mouse MAb & Rabbit MAb products were released. 12 ELISA Pair Set products were released. 2010 ISO9001 Certificated. 04 2011 05 1000+ antibodies online: for FCS, IHC, IF... The customers are from 40+ countries. 06 Beijing MAb Upstream R & D Technology Key Laboratory was founded. 2012 Beijing Protein & Antibody Engineering Technology 05 Research Center was founded. 12000 reagents in stock, including 2300 antibodies. 06 Ship to over 7000 customers from 70 countries. Partnerships and Co-branding with Life Technologies. 08 Finished the development of the spike protein and nucleocapsid of novel 12 coronavirus within 50 days after the sequence release. 2013 Developed the HA & NA protein of H7N9 avian influenza virus in 12 days 04 based on the virus sequence release. 2014 ELISA Kit products were released. 10 2015 PD1，PD-L1，CD3 and CD28 neutralization antibodies for cell therapy were 02 released. 07 30000+ reagents: including 5000+ proteins，7500+ Ab，500+ ELISA Kit， and IP Kit-Immunomagnetic Beads were released. 2016 New 37,000 m2 Research and Development Center were built. 01 Immunohistochemistry Antibody The key for successful IHC—High quality of primary antibodies 1 Better quality than other brands of IHC antibodies Processing& Slides Sinobiological InC. Company A Company B 2 Dewax& Rehydrate 3 CD71(11020-R016)- human placenta Antigen Retrieval Strict standards, selecting the best one 4 30% H2O2 5 Serum Blocking Colon 1-√ Colon 2-× Colon 3-× 6 CGA(100256-R204)-human adrenal gland Primary antibody Accurate staining verified 7 Rinse 8 Secondary antibody CD147(10186-R125)- Insulin(11038-T08)- S100A12(11143-RP02)- human esophagus human pancreas human spleen 9 Rinse Stable Quality guaranteed between different Lots 10 DAB 11 Mount Lot. 1 Lot. 2 Lot. 3 Order online: www.sinobiological.com [email protected] Fax:+86-10-5102 9969 Tel:400-890-9989 Immunofluorescence Antibody High Specificity High Sensitivity Validated by antigen blocking assay, multiple cell Lower concentration antibody solution, which can types, other applications (WB, IP, IHC or FC) avoid false/negative result. LAMP1(11215-R107) Red: LAMP1 Green: Microtubule Blue: DAPI Hela Hela Hela Hela NIH/3T3 A431 antibody + + HSPD1(101240-T38) PTBP1(101043-T46) P4HB(50638-R023) JAM-A(10198-MM04) antigen - + High Reproducibility Ensure better reproducibility for your experiment. Positive Block Hela 2013-8-1 2014-1-2 2015-1-13 2015-8-11 Immunofluorescence staining of GP73 in Hela cells Immunofluorescence staining of GP73 in Hela cells using SBI antibody using other brand antibody(green), and counterstained (red), and counterstained with DAPI (blue). After two years, the antibody with DAPI (blue). The antibody lose its efficacy after has excellent efficacy. Note: The same batch (Lot#) of anti-GP73 antibody 0ne year. Note: The same batch (Lot#) of anti-GP73 is tested at different time. antibody is tested at different time. All organelle markers NucleusNucleus Tubulin: anti-tubulin (100109-MM05) Lysosome: anti-LAMP1 (11215-R107) TubulinTubulin NucleolusNucleolus Plasma membrane: anit-PVR (50259-R305) Mitochondia: anti-C1QBP (11874-MM09) LysosomeLysosome GolgiGolgi Nucleus: anti-POU2F1 (100726-T34) Nucleolus: anti-Ki67 (13180-MM01) Golgi: anit-GP73 (13066-T24) ER: anti-PDI (10827-MM03) PlasmaPlasma membrane membrane EndoplasmicEndoplasmic Reticulum Reticulum MitochondiaMitochondia Order online: www.sinobiological.com [email protected] Fax:+86-10-5102 9969 Tel:400-890-9989 ELISA ELISA Antibody For Unique Model species Validated by High Quality Recombinant Proteins Various of Applications Sinobiological provides more Sinobiological is the largest independent manufacturer of ■ Primary Ab than 300 ELISA antibodies for recombinant proteins. Most proteins are more than 90% in ■ Second Ab unique model species. purity, and have good bioactivities. ■ Capture Ab ■ Rabbit Enzyme-labeled Ab Sus scrofa (pig) Aequorea victoria Rhesus ■ Direct ELISA E. coli Ferret ■ Indirect ELISA Canine (dog) Macaca ■ Competitive ELISA Virus ■ Sandwich ELISA ELISA Pair Set Provide 300 + High Quality ELISAs ■ Monoclonal antibody as capture, has better specific and quantitative accuracy ■ Human, Mouse, Rat , Virus and other targets ■ Suitable for the quantitative detection of various samples ■ Cost-saving Hot product Product Name Cat. No. Product Name Cat. No. HIV-1 p24 SEK11695 Human HER2 / ErbB2 / CD340 SEKA10004 HIV-1 gp120 SEK11233 Human TREM-2 SEK11084 RSV Fusion Glycoprotein SEK11049 Human Vitronectin / VTN SEK10424 H1N1 (Swine Flu 2009) HA SEK001 Human CD171 / N-CAML1 / L1CAM SEK10140 H1N1 (A/Puerto Rico/8/1934) HA SEK11684 Human CD83 SEK11763 H5N1 (Avian Flu) HA SEK002 Human EGFR / HER1 / ErbB1 SEK10001 H7N9 (A/Anhui/1/2013) HA SEK40103 Human CD146 / MCAM / MUC18 SEK10115 Human IL-1 beta / IL1B / IL-1F2 SEK10139 Human CEACAM6 / CD66c SEK10823 Human IL6 / Interleukin-6 / IFNB2 SEKA10395 Mouse IL-16 / Interleukin-16 SEK51303 Human IL-5 / Interleukin 5 SEK15673 Mouse PCSK9 SEK50251 Human NGF / NGFB SEK11050 Rat PCSK9 SEK80005 Pair Set custom services ! Order online: www.sinobiological.com [email protected] Fax:+86-10-5102 9969 Tel:400-890-9989 Western Blotting Antibody Binding to recombinant & natural proteins Being validated by various cell & tissue lysate KDa A KDa A 70 95 55 72 40 55 43 35 34 25 26 FCM 15 IP 17 IF / ICC IHC Recombinant protein (0.5ng) Jurkat cell lysate Suitable for additional applications, including Various special-tag antibody FACS, IHC, IP or IF Human Beta-Tubulin (100109-MM05) HA (100028-T36) S-tag (101290-T38) KDa A B C D E F G H I J K L M KDa A B C D KDa A B C D E F G 170 55 130 40 100 100 35 70 70 55 55 40 40 A549 293T HEGP2 Daudi MOLT-4 35 35 Mouse brainMouse liver 25 25 HEPG2Jurkat mebrane membrane293T membraneK562 membraneHELA membrane RAW264.7 membrane 15 15 Human HSPA1A (11660 –R001) GFP (13105-R208) E-tag (101292-T38) KDa A B KDa A B C D E F G H I J K L KDa A B C D E F G 100 100 70 100 70 55 70 55 55 40 40 35 C6 35 A431 A549 Hela K562 293T HepG2 HL-60 Jurkat MCF7 MOLT4 HCT116 25 25 15 15 We offer you not only high-quality antibodies, but also WB CRO services ■ We have advanced equipment and instruments. ■ We have a wealth of experience and can provide high- throughput antibody detection- 10000 + per year. ■ We have 100+ types of cell and tissue lysates, 1000 + WB antibodies and a variety of high quality secondary antibodies. Order online: www.sinobiological.com [email protected] Fax:+86-10-5102 9969 Tel:400-890-9989 Immunoprecipitation Immunoprecipitation Antibody Various of IP Antibodies ( 900+ , and include important targets and protein tags) Host & Clone : Rabbit Pab & Mab, Mouse MAb Target Species: Human, Mouse, Rat, Dog, Virus… Research Areas: Cell Receptor , Interleukin, Cytokine, Diagnostic , Cancer , Stem Cell , Biomarker …… High Specificity and Sensitivity ( Detected target protein as low as 1 ~ 4μg Ab) GSTK1 (14291-T52) V5 Tag (100378-T36) PCNA (101118-T46) LAMP1 (11215-R107) Strict Quality Control with High Quality Assurance Immunomagnetic
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