Surgical Options for the Treatment of Hyperopia
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FEATURE Surgical options for the treatment of hyperopia BY ALLON BARSAM he modern refractive surgeon has a variety of options available to treat patients T with hyperopia who wish to be independent of spectacles and contact lenses. Unlike in low myopia where presbyopic patients may have the ability to see well for close work without spectacles, hyperopia confers no such advantage and the successful treatment of the presbyopic hyperope can be particularly rewarding for both patient and surgeon alike. However, despite the array of available options, the surgical management of this condition remains one of the greatest challenges in refractive surgery. It should be noted that all of the surgical options described in this article could also be combined with treatment to correct any coexisting astigmatism in these hyperopic patients. The Figure 1: Corneal topography following an outdated technique with small ablation zone hyperopic laser with a steepened central corneal and a small optical zone. specific surgical considerations for astigmatism treatment will be covered in a subsequent article. This article has manifest refraction, while being the (LASEK), epi-LASEK and advanced not considered thermal treatments best option for immediate restoration surface ablation. The outcomes and such as conductive keratoplasty as of good unaided distance vision may risks are essentially the same. The most surgeons have abandoned these result in regression of effect when advantages of this technique over techniques as the rate of regression of the patient approaches presbyopia laser in situ keratomileusis (LASIK) effect and the potential for induction of and the residual hyperopia which are the avoidance of the potential for irregular astigmatism are unacceptably may have been untreated becomes flap-related complications. However, high. unmasked. Secondly, hyperopes often in hyperopia there are several unique The overall prevalence of hyperopia have different anatomy to myopes considerations. Some of these is around 10%, affecting approximately in terms of corneal shape, anterior considerations are also of relevance for 14 million people in the US [1,2]. chamber depth and axial length; this hyperopic LASIK [5]. Hyperopia may be classified by has implications for the feasibility Hyperopic excimer laser refractive the degree of refractive error: low and safety of laser refractive surgical surgery relies on laser pulses applied hyperopia is +2.00D or less; moderate correction, implantable collamer lenses in an annulus around the mid corneal hyperopia ranges from +2.25D to and accurate lens calculations for periphery in order to induce central +5.00D; and high hyperopia is +5.25D pseudophakic intraocular lenses [3,4]. corneal steepening, increase corneal or more. These factors will be discussed in more power thereby reducing hyperopia There are several reasons why the detail for each individual treatment in (Figure 1). More laser pulses and a surgical management of hyperopia turn. greater amount of tissue ablation are can be particularly challenging. necessary in a hyperopic treatment Firstly, hyperopic patients who Advanced surface laser than for the equivalent myopic patient. are not yet presbyopic may have a ablation Furthermore, the location of the laser significant disparity between their Surface laser excimer ablation goes by activity in the mid-periphery of the manifest (dry) and latent (cycloplegic a variety of different names including: cornea, rather than in the centre as / wet) refractions. This means that a photorefractive keratectomy (PRK), in myopia, makes surface treatment refractive treatment targeted on their laser epithelial keratomileusis more susceptible to the induction eye news | AUGUST/SEPTEMBER 2016 | VOL 23 NO 2 | www.eyenews.uk.com FEATURE of corneal haze. Some regression of keratometry that will still allow good perceive a significant loss in quality effect is well described in all hyperopic quality of vision and in general most of their intermediate and near vision laser refractive surgery, as the mid- surgeons prefer not to leave the cornea even with the advanced lens options peripheral location of treatment more than 50.00D postoperatively. described earlier. Furthermore, the is more susceptible to stromal Hyperopic treatments are more prone risk of retinal detachment makes this remodeling than the central cornea; to quality of vision issues if the laser an inferior choice to phakic intraocular this is particularly true of hyperopic treatment is decentred at all so for high lenses for these patients. surface laser treatments as the removal hyperopic treatments targeting the of the epithelium triggers a more laser on the corneal vertex rather than Phakic intraocular lenses profound wound healing response. For on the pupil may be preferable. Finally, Phakic intraocular lenses are the this reason, most surgeons reserve as laser pulses are applied more in the treatment of choice for patients who are surface laser treatments only for low periphery of the cornea and a larger pre-presbyopic or unsuitable for laser hyeropia in patients where LASIK is corneal flap is required, hyperopic laser eye surgery but satisfy the anatomical not possible or unadvisable, such as in treatments tend to be more prone to requirements for safe placement of the those with thin corneas. dry eye postoperatively. lenses. The operation involves placing For many of the reasons described an intraocular lens into the eye without LASIK thus far some surgeons have a lower removing the natural lens of the eye. LASIK remains the treatment of choice threshold for recommending refractive The advantage of this over RLE is the in patients with low hyperopia who are lens exchange in hyperopic presbyopes preservation of normal accommodative not yet presbyopic, providing patients than in myopic presbyopes. function and a much lower risk of retinal fulfill the standard safety criteria for There have been several studies detachment. There are three main options: laser vision correction such as a normal published recently looking at • Placement in the ciliary sulcus corneal topography and an adequate combining hyperopic LASIK with in front of the natural lens of the tear film. corneal crosslinking [7], as well as eye and behind the iris such as the The LASIK flaps make wound healing studies looking at different modalities Staar Visian Implantable Collamer and regression of effect less of an of laser vision correction such as small Lens (ICL). issue here than with surface laser incision lenticule extraction (SMILE) • Iris clip lens that sit in the anterior treatments. [8]. As yet there is not evidence for chamber such as the Ophtec Artisan In a prospective study of US naval superiority of these treatments in long- or Artiflex lenses. aviators, 25 eyes underwent LASIK term randomised controlled studies. • Anterior chamber angle supported for hyperopia with the VISX S4 lenses such as the Alcon Cachet (Abbott Medical Optics, Abbott Park, Refractive lens exchange lens. Illinois, US) [6]. Mean preoperative In patients who are already Each of these options has various spherical equivalent was +1.86D, and experiencing the symptoms of advantages and disadvantages. The the spherical equivalent improved to presbyopia, refractive lens exchange author’s preference is the Visian ICL as +0.005D three months postoperatively. (RLE) represents a good surgical this causes the least endothelial cell loss In this military population, 13% of option [9]. The procedure involves and, in fact, long-term endothelial cell loss hyperopes achieved 20/10 uncorrected removing the natural lens of the eye beyond the first few years is thought to be distance visual acuity (UDVA) and 52% and replacing it with an intraocular negligible. It can be used to treat hyperopia had 20/12 UDVA. Visual recovery was lens. Advantages include: no regression with lens powers up to +21.00D. The main fairly rapid, with uncorrected distance of refractive effect; no long-term disadvantage of the ICL is that there is visual acuity (UDVA) at least 20/20 in risk of dry eye; removal of the risk of a slightly higher chance of developing 76% of eyes at one week, and only one angle closure glaucoma in eyes that cataract with this lens. However, with the eye lost one line of corrected distance otherwise have a predisposition to this; newest centraflow technology to allow visual acuity (CDVA). and avoiding the risk of cataract in the normal circulation of aqueous over the The author’s personal preference is future. The main disadvantage of this anterior lens this risk is now also thought to treat up to 4.00D of hyperopia but over laser eye surgery is the risk of to be very low indeed. Furthermore, this not more due to risk of regression of sight loss due to bleeding or infection, risk is also lowered by not using this lens in effect and residual hyperopia when which is estimated to be around 1:2000 patients who are well into the presbyopic treating higher levels. Hyperopic [9], whereas the risk of significant loss age range. All three options require an presbyopes can still be treated of vision (more than two lines of best adequate anterior chamber depth for safe with LASIK providing the degree corrected visual acuity) in laser eye implantation. of hyoperopia is low enough to surgery is much lower [10]. There is also Long-term follow-up on the Visian ICL accommodate the extra treatment a long-term risk of retinal detachment phakic IOL (STAAR Surgical, Monrovia, required for a laser blended vision [11]. California, USA) has shown excellent treatment (mini-monovision). For There are several lens options results. A study followed a group of example, if the non-dominant eye of a for providing uncorrected distance, hyperopes with preoperative spherical 60-year-old refracted to +2.00D then intermediate and near vision. These equivalent of +4.80D for three years [12]. in order to aim to leave this eye -1.50D include: monovision; accommodating Mean UDVA was 20/23 at three years, with spherical equivalent postoperatively lenses; multifocal lenses of various 69% achieving at least 20/20.