PRESBYOND Laser Blended Vision Practical Guide
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PRESBYOND Laser Blended Vision Practical Guide Disclaimer: This practical guide was produced independently by Dan Z Reinstein, MD MA(Cantab) FRCSC DABO FRCOphth FEBO1, 2, 3, 4 Glenn I Carp, MBBCh, FC Ophth (SA)1 Timothy J Archer, MA(Oxon), DipCompSci(Cantab)1, 4 Sharon Ritchie, BSc (Hons), MCOptom1 1 London Vision Clinic, London, UK 2 Department of Ophthalmology, Columbia University Medical Center, NY, USA 3 Centre Hospitalier National d’Ophtalmologie, Paris, France 4 Biomedical Science Research Institute, University of Ulster, Coleraine, Northern Ireland Financial Disclosure: Dr Reinstein is a consultant for Carl Zeiss Meditec (Carl Zeiss Meditec AG, Jena, Germany) and has a proprietary interest in the Artemis technology (ArcScan Inc, Golden, Colorado) through patents administered by the Center for Technology Licensing at Cornell University (CTL), Ithaca, New York. Dr Carp receives travel expenses from Carl Zeiss Meditec. The remaining authors have no proprietary or financial interest in the materials presented herein. Preoperative 1. Pre-operative testing protocol 2. Manifest refraction 3. Dominance testing 4. Laser Blended Vision tolerance assessment 5. What myopic target to expect 6. Laser Blended Vision explanation and patient counselling Postoperative 7. Postoperative evaluation 8. Postoperative visual course 9. Cross-blur management at final outcome 10. Appendix A – Preoperative tolerance test examples 11. Appendix B – Postoperative cross-blur and enhancement examples 2 1. Pre-operative testing protocol Highlighted topics are particularly relevant for PRESBYOND • History. Motivation for surgery, previous ocular • Cirrus OCT corneal and epithelial pachymetry. history (including detailed history of contact lens wear, • Undilated WASCA aberrometry. period of wear, type of lens, wear modality, last worn, • Ocular Response Analyser. comfort or visual symptoms associated with wear), family • CDVA and DCNV with WASCA sphero/cyl refraction. ocular history, detailed medical history, general health, • Manifest distance refraction (measured as standard medications, allergies, previous refractions, night vision at 6m) and CDVA and DCNV. symptoms with spectacles and/or contact lenses. Ocular • Laser Blended Vision tolerance test to find optimal symptoms, especially dry eye symptoms with/without anisometropia. contact lenses and pattern, photophobia. • Monocular distance visual acuity with +1.50 D blur • Ocular dominance by four methods: preferred sighting (for presbyopic patients). of a camera using a disposable camera as a prop, shooting • Mesopic contrast sensitivity testing (Vector Vision CSV simulation, view-finder hole test, and pointing. 1000). • Pupil reactions (PERRLA and presence or not of APD). • Slit Lamp examination. • Ocular motility testing. • TBUT. • Confrontational fields testing. • Schirmer 1b testing. • Cover testing at distance and near, with and without • Goldmann tonometry. glasses. • Cycloplegic refraction & CDVA (after instillation of • Monocular and binocular distance UCVA (using the 1.0% Tropicamide). Vector Vision CSV 1000 log MAR chart with internally • Dilated WASCA aberrometry (minimum pupil diameter regulated background illumination to ensure the contrast 6.0 mm). is the same irrespective of the room lighting). • Dilated fundus examination using both head-mounted • Monocular and binocular near UCVA. BIO and Superfield/78D lens. • Monocular and binocular intermediate UCVA. • Night vision simulation if required. • Lensometry of current spectacles and CDVA and • Night vision questionnaire (QoV validated questionnaire). DCNV with this refraction. • OSDI dry eye questionnaire. • Procyon dynamic bilateral IR pupillometry measured • KC Screening assessment considering objective tests at three different light levels: dark (0.0 Lux), scotopic and patient history. (0.04 Lux), mesopic low (0.4 Lux). • Insight Very High Frequency Digital Ultrasound • Pentacam tomography (or tomography equivalent). (if required). • Atlas topography. 3 2. Manifest refraction The goal of manifest refraction in refractive surgery is to determine the optimal sphere and cylinder lenses that will maximise visual acuity for a particular eye. Refraction for glasses is often considered to be an art, whereas refraction for surgery should be considered to science. When refracting for spectacles, the artistic elements include pushing axes to the horizontal, minimising the cylinder used, and keeping cylinder axis between the eyes orthogonal, etc. Refraction for refractive surgery is quite different in that for example we attempt to maximise cylinder and determine the exact axis of astigmatism irrespective of verticality and orthogonality to the opposite eye. Below are the flow charts that describe the manifest refraction protocol (Figure 1) and binocular balance protocol (Figure 2) that we routinely use. With this technique, we have demonstrated between observer reproducibility equivalent to within observer repeatability, in the order of 0.25 D.1 Monocular Manifest Refraction Protocol START: Initial dilated aberrometry Rx Put up 20/40 line Check visual acuity Put up Jackson Cross Put up smallest line No Add +0.25 DS Cyl = 0 Cyl < 0 No Add +0.25 DS Does this blur Test 4 positions Does this blur them a little? them a little? of axis Refine axis Yes Yes Put in -0.25 DC Refine power Remove the added +0.25 Remove the added +0.25 If >0.25 D change, refine axis Add -0.25 DS Yes Add -0.25 DS Remove Jackson Cross Can you read more letters? Can you read more letters? No Clear preference for power? No Yes No Find smallest line Yes Remove the END Remove the added -0.25 Test 0.25 DC difference added -0.25 Figure 1: Flow chart describing our monocular manifest refraction protocol. 4 Binocular Balance Protocol Add +1.50 DS lenses into both eyes* If sphere changed in one eye, remove +1.50 DS lens and check CDVA Put up 20/200 line and ask how far down the chart the patient can read Put up smallest line If can read better than 20/63 they are under- Add +0.25 D binocularly No plussed, so add plus binoculary until blurred Does this blur them a little (wait 5 secs)? Cover R and L eye alternately with your hand Both eyes see and ask which is better (sharpness not brightness) Yes the same using the 20/200 line Remove the added +0.25 One eye sees better than the other Final Binocular Rx Add +0,25 DS to eye seeing better *N.B. This is for a testing distance of 2.40 m using the CSV-1000 chart – equivalent to +1.08 D Figure 2: Flow chart describing our binocular balance protocol. 3. Dominance testing Eye dominance is recognized as a very important factor in monovision success and is based on the hypothesis that the non- dominant eye would be more easily suppressed for distance when vision is blurred than the dominant eye. We routinely evaluate the ocular dominance using four methods: the ‘hole test’, pointing, a disposable camera, and shooting a rifle. We also record the handedness of the patient. 1. The ‘hole test’ involves the patient binocularly aligning a distant object through a 1” diameter hole in a white A4 sheet of paper, held at arm’s length in landscape format with each hand holding either end. The eyes are alternately covered while looking through the hole. The eye with which the object appears most centered through the hole is deemed to be the dominant eye. 2. Pointing involves the patient pointing at a spot light source 6 meters from the patient so that their finger and the light source are visually aligned. Each eye is then occluded and the eye with the least separation between their finger and the spot is deemed to be the dominant eye. 3. A disposable camera is given to the patient and they are asked to pretend to take a photograph. The eye used to align the camera is deemed to be the dominant eye. 4. The patient is asked to pretend to shoot a rifle and the eye the patient keeps open to sight the rifle is deemed to be the dominant eye. 5 4. Laser Blended Vision tolerance assessment The standard micro-monovision protocol would correct the dominant eye to plano and the non-dominant eye to -1.50 D irrespective of age. Patients should be tested for tolerance with these refractions, with tolerance evaluated as the amount of cross-blurring reported by the patient during simulation of the intended postoperative refraction using a phoropter. Cross-blurring is a term used to describe a lack or reduction of interocular blur suppression. After first completing a full manifest refraction in both eyes, the micro-monovision assessment is performed as outlined below 1. The examiner stands in front of the patient to block his/her view of the visual acuity chart while concurrently setting the ‘R’ (retinoscopy +1.50 D) lens into the non-dominant eye. 2. The examiner then moves to the side of the patient allowing him/her to once again view the chart. 3. After a few seconds, the examiner asks the patient “how does that look?” 4. If the patient responds that everything looks fine, the examiner then asks “nothing strange?” and “no ghosting?” 5. The examiner asks the patient to read the smallest letters he/she can see at distance. 6. Next, the near chart is brought in front of the patient at 40 cm and the patient is asked to read the smallest print that is comfortable to read. 7. The examiner uncovers the distance chart again and asks the patient to read the smallest print he/she can. When removing the near chart, this should be done slowly and in such a way to uncover the distance eye first to allow the brain a chance to adapt. 8. At this point, the examiner covers the dominant eye while saying to the patient “were you at all aware of the fact that [examiner covers the dominant eye] this eye [the non-dominant eye] was very blurred at distance?” 9. If the patient states that he/she was completely unaware of this, the patient is deemed to be tolerant of a +1.50 D ‘add’.