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Umschlag_fp_19_Internet.qxp_Layout 1 02.07.19 13:02 Seite 1 Umschlag_fp_19_Internet.qxp_Layout 1 02.07.19 13:02 Seite 2 55TH ANNUAL MEETING OF THE EUROPEAN ASSOCIATION FOR THE STUDY OF DIABETES Content Page EASD . 4 General Information . 10 EASD Community Plaza . 14 Programme at a Glance . 22 EASD e-Learning . 30 EFSD Mentorship Programme . 31 EUDF Symposia . 32 Tuesday, 17 September . 34 Claude Bernard Lecture . 34 Poster Event A . 45 Poster Event B . 48 Camillo Golgi Lecture . 56 Albert Renold Lecture . 58 Rising Star Symposium . 60 Wednesday, 18 September . 62 Poster Event C . 74 Poster Event D . 77 Diabetes Prize for Excellence Lecture . 84 Thursday, 19 September . 89 Poster Event E . 100 Poster Event F . 103 Minkowski Lecture . 110 Friday, 20 September . 114 Posters . 131 Index of Presenting Authors . 264 Index of Symposium Speakers . 279 European Foundation for the Study of Diabetes (EFSD) . 281 Symposia on the occasion of the 55th EASD Annual Meeting . 285 Industry Symposia, Meet the Expert Sessions and Exhibition on the occasion of the 55th EASD Annual Meeting (organised by INTERPLAN) . 293 56th EASD Annual Meeting . 324 DEAR MEMBERS AND GUESTS, It will be my great honour and pleasure to welcome you to the 55th Annual Meeting of the European Association for the Study of Diabetes e.V. which will take place in Barcelona from 16 to 20 September 2019. EASD Under the chairmanship of EASD Honorary Secretary, Mikael Rydén, the Scientific Programme Committee selected 1195 abstracts for presentation from a total of 2003 submitted. The outstanding programme will comprise of stimulating symposia, numerous oral and poster presentations as well as Prize Lectures, honouring the achievements of distinguished researchers. The EASD Annual Meeting offers the ideal opportunity to interact and communicate with researchers of the highest calibre from all over the world. I hope you will enjoy the wide choice of lectures, presentations and posters. I look forward to welcoming you in Barcelona, a city renowned for its history, culture and architecture, and wish you a very successful and inspiring EASD Annual Meeting. David R. Matthews President EASD/EFSD 2 WELCOME ADDRESS On behalf of the EASD Board and the 2019 Scientific Programme Committee, I have the pleasure of welcoming you to the 55th EASD Annual Meeting in Barcelona. The EASD meeting brings together a broad span of professionals and covers almost every scientific and EASD clinical aspect of diabetes. The quality of the meeting is to a large part determined by the participants who contribute by presenting their most recent studies. Looking through the programme I hope that everyone will find interesting topics which together help us advance the field. To convene here in Barcelona will offer ample opportunities to socialise and network with peers from all over the world and perhaps discuss future collaborations. Needless to say, this city offers great options outside of the scientific programme hours. History, architecture, beaches and gastronomy provides a variety of choices on how to spend your evenings. We look forward to seeing you in Barcelona. Mikael Rydén Honorary Secretary EASD 3 BOARD President D.R. Matthews, UK Senior Vice-President and Chair PGEC C. Mathieu, BE Vice-President M. Blüher, DE Honorary Secretary M. Rydén, SE EASD Honorary Treasurer R. Weitgasser, AT Editor-in-Chief, DIABETOLOGIA S.M. Marshall, UK Chairman EFSD S. Del Prato, IT Board Member F. Gribble, UK Board Member P.-H. Groop, FI HONORARY MEMBERS Sir G. Alberti, UK D. Andreani, IT J.-P. Assal, CH P. Bennett, US A. Cerami, NL E. Cerasi, IL O.B. Crofford, US T. Deckert, DK J. Eng, US A.-M. Felton, UK E. Ferrannini, IT P. Freychet, FR P.A. Halban, CH B. Hellman, SE V. Jörgens, DE F. Kaufman, US E. Kohner, UK H. Lebovitz, US P. Lefèbvre, BE J. Ludvigsson, SE W. Malaisse, BE C.E. Mogensen, DK J. Nerup, DK L. Orci, CH H.-H. Parving, DK O. Pedersen, DK G.M. Reaven, US J. Roth, US M.-R. Taskinen, FI R. Unger, US E. Van Obberghen, FR G. Viberti, IT M. Vranic, CA W. Waldhäusl, AT J.D. Ward, UK C.B. Wollheim, CH P. Zimmet, AU HEADQUARTERS DÜSSELDORF Managing Director, Chief Medical Officer M. Grüsser Rheindorfer Weg 3 40591 Düsseldorf Germany Phone: +49-211-7584690 www.easd.org 4 HISTORY OF THE EASD ANNUAL MEETINGS 1965 Montecatini 2000 Jerusalem 1966 Aarhus 2001 Glasgow 1967 Stockholm (IDF) 2002 Budapest 1968 Louvain 2003 Paris (IDF) 1969 Montpellier 2004 Munich 1970 Warsaw 2005 Athens 1971 Southampton 2006 Copenhagen EASD 1972 Madrid 2007 Amsterdam 1973 Brussels (IDF) 2008 Rome 1974 Jerusalem 2009 Vienna 1975 Munich 2010 Stockholm 1976 Helsinki 2011 Lisbon 1977 Geneva 2012 Berlin 1978 Zagreb 2013 Barcelona 1979 Vienna (IDF) 2014 Vienna 1980 Athens 2015 Stockholm 1981 Amsterdam 2016 Munich 1982 Budapest 2017 Lisbon 1983 Oslo 2018 Berlin 1984 London 1985 Madrid (IDF) 1986 Rome 1987 Leipzig 1988 Paris 1989 Lisbon 1990 Copenhagen 1991 Dublin 1992 Prague 1993 Istanbul 1994 Düsseldorf 1995 Stockholm 1996 Vienna 1997 Helsinki (IDF) 1998 Barcelona 1999 Brussels 5 The mission of EASD is to promote excellence in diabetes care through research and education Since its foundation in 1965, EASD has been organising an Annual Meeting, which has become the largest international annual conference on diabetes research worldwide. Although the meetings have grown so dramatically, they are still driven by the academic traditions of the founding members. EASD The EASD Meeting is a meeting of members where guests are welcome. Chairpersons of oral presentations and poster sessions are chosen exclusively from the EASD membership. The abstracts are evaluated on a strictly anonymous basis and the selection is based exclusively on the quality of the science, regardless of the place of work. The EASD Honorary Secretary is solely responsible for inviting speakers and chairpersons for symposia and lectures. Comments, advice and proposals from the membership and the Programme Committee are welcome. None of the speakers or chairpersons at the EASD Annual Meeting receives an honorarium; reimbursement of their travel costs is exclusively provided by the Association. EASD and its Foundation EFSD are academic charities dedicated to diabetes research. As an academic society, EASD encourages cooperation with industry and other institutions conducting and funding diabetes research. EASD is committed to transparency. In 2005, its Annual Meeting endorsed the following policy with respect to duality of interest: prior to the Meeting speakers invited to symposia or lectures declare to EASD the existence of any relationship or arrangement that could be reasonably considered to affect the content of the presentation. Invited speakers who declare a duality of interest are asked by EASD to disclose this on a slide of their presentation. Any occasional, positive balance resulting from the Annual Meeting is used to encourage further diabetes research in Europe. Increasingly, major end- point related trials are carried out to evaluate diabetes treatments. EASD encourages these trials and provides an outstanding forum to announce their results to the scientific community. 6 The EASD regulations on the presentation of major clinical trials state that all data of the trial must be openly available, and clear information should be provided on the role of the funding source/sponsor on study design, data collection, analysis and interpretation of the data. Moreover, a commentator, nominated by the EASD Honorary Secretary, must have prior access to the data in order to prepare an unbiased review. EASD Meetings are organised in such a way as to ensure the academic independence of physicians and scientists as the patients’ advocates. Article 1, Section 2 Statutes of the European Association for the Study of Diabetes, EASD Diabetologia 1, 256-260 (1965): The aims of the Association are to encourage and support research in the field of diabetes, to rapidly spread acquired knowledge and to facilitate its application. 7 EASD POSTGRADUATE COURSES EASD 8 Copyright Eleanor Kennedy EASD HAS THE FOLLOWING STUDY GROUPS Artificial Insulin Delivery, Pancreas and Islet Transplantation Study Group (AIDPIT) Diabetes and Cancer Study Group (DCSG) Diabetes and Cardiovascular Disease Study Group (DCVD) Diabetes and Nutrition Study Group (DNSG) EASD Diabetes Education Study Group (DESG) Diabetes Neuropathy Study Group (NEURODIAB) Diabetes Pregnancy Study Group (DPSG) Diabetic Foot Study Group (DFSG) European Diabetes Epidemiology Group (EDEG) European Diabetic Nephropathy Study Group (EDNSG) Exercise and Physical Activity Study Group (ExPAS) Eye Complication Study Group (EASDec) Incretin Study Group (INCSG) Islet Study Group (ISG) Non-alcoholic fatty liver disease (NAFLD) Psychosocial Aspects of Diabetes Study Group (PSAD) Reactive Metabolites (RMSG) Study Group on Genetics of Diabetes (SGGD) Biomedical Imaging in Diabetes Study Group (DIAB IMAGE) Study Group on Primary Care Research in Diabetology (PCDE) 9 GENERAL INFORMATION Meeting venue: Fira Barcelona Gran Via South Access Av. Joan Carles I, 64, 08908 L’Hospitalet de Llobregat Barcelona www.firabarcelona.com/en/gran-via First Aid: The First Aid Centre is located in P3. EASD In case of emergency: Contact the nearest staff member. Registration: Sunday 10:00 - 18:30 Monday 08:00 - 18:30 Tuesday, Wednesday and Thursday 07:00 - 19:00 Friday 07:00 - 14:00 Children under the age of 18 are not permitted to enter. Delegates receive: - Admission to Scientific Programme - Final Programme book - Admission to the Industry Exhibition - Free public transportation ticket (valid for 5 days) - Coffee breaks and lunch snacks from Tuesday to Friday Certificate of Attendance: The Certificate of Attendance can be downloaded from EASD’s homepage from Tuesday, 17 September onwards. EACCME Certificate: The EACCME certificate can be downloaded from EASD’s homepage from Monday, 23 September onwards or printed at the CME counters in the Entrance Hall, starting Thursday, 19 September at 15:00. Press Registration: Press delegates can register at a special press registration desk.