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Curriculum Vitae Miriam Cnop

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Curriculum Vitae Miriam Cnop Curriculum vitae Miriam Cnop CURRICULUM VITAE Miriam Cnop, MD, PhD ADDRESS Home: Boudewijnlaan 21 1700 Dilbeek, Belgium Phone 32.2.270.37.79 Work: Division of Endocrinology, Department of Medicine, Erasmus Hospital and ULB Center for Diabetes Research, Faculty of Medicine Université Libre de Bruxelles 808, Route de Lennik 1070 Brussels, Belgium Phone 32.2.555.63.05 Fax 32.2.555.62.39 [email protected] DATE AND PLACE OF BIRTH December 25, 1970, Elsene, Belgium NATIONALITY Belgian LANGUAGES Dutch (mother tongue), English (fluent), French (fluent), German (basic), Portuguese (basic) EDUCATION HIGH SCHOOL 1982-1988 Orientation Latin/Mathematics, Royal Atheneum Tervuren, Belgium UNIVERSITY Graduate Vrije Universiteit Brussel, Brussels, Belgium 1988-1995 Medical Doctor Summa cum Laude Magna cum Laude Magna cum Laude Magna cum Laude Summa cum Laude Summa cum Laude Summa cum Laude First Prize of the Faculty Jury for the Best Medical Curriculum Graduate thesis: ‘Effects of lipids on rat pancreatic cells’, Diabetes Research Center, Vrije Universiteit Brussel (Supervisor Prof D Pipeleers) Post-graduate 1 Curriculum vitae Miriam Cnop 1995-2002 PhD program, Faculty of Medicine, Vrije Universiteit Brussel, Brussels, Belgium (Supervisor Prof Daniel Pipeleers) Supported by a scholarship of the Belgian Fund for Scientific Research (Aspirant FWO) Title of the PhD thesis ‘Lipids, putative cell pathogens in type 2 diabetes’ (date of defense: May 2002) 1995-2001 Specialization in Internal Medicine, Vrije Universiteit Brussel, Belgium 2000-2001 Post-doctoral Fellow, Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington, Seattle, USA (Supervisor Prof Steven E Kahn) 2001-2002 Specialization in Endocrinology, Department of Medicine, Vrije Universiteit Brussel, Brussels, Belgium 2002-2003 Specialization in Endocrinology, Department of Medicine, Université Libre de Bruxelles, Brussels, Belgium LICENSURE AND CERTIFICATION 1995 Medical Practice License, Brussels, Belgium 2001 Internal Medicine Certification, Brussels, Belgium 2010 Endocrinology Certification, Brussels, Belgium APPOINTMENTS 1995-1999 Scholarship of the Belgian Fund for Scientific Research (Aspirant FWO) Diabetes Research Center, Vrije Universiteit Brussel, Belgium Combined clinical (residency) and scientific (PhD) training 1999-2000 Medical Resident, Department of Medicine, Academisch Ziekenhuis Vrije Universiteit Brussel, Belgium 2000-2001 Senior Research Fellow in the Division of Metabolism, Department of Medicine, University of Washington, Seattle, Washington, USA Supported by a scholarship of the Belgian American Educational Foundation 2001-2002 Endocrinology Fellow, Department of Medicine, Academisch Ziekenhuis Vrije Universiteit Brussel, Belgium 2002-2003 Endocrinology Fellow, Department of Medicine, Erasmus Hospital Research Fellow, Laboratory of Experimental Medicine, Université Libre de Bruxelles, Brussels, Belgium 2003-2007 Staff Physician (Résident), Division of Endocrinology, Department of Medicine, Erasmus Hospital, Brussels, Belgium Research Fellow, Laboratory of Experimental Medicine, Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium 2005-2010 Halftime Research Fellowship of the Belgian Fund for Medical Scientific Research (FRSM) at the Laboratory of Experimental Medicine, Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium 2007-2016 Deputy Head of Clinic (Chef de Clinique Adjoint), Division of Endocrinology, Department of Medicine, Erasmus Hospital, Brussels, Belgium 2010-present Visiting professor at Hunan Agricultural University, Changsha, China 2011-present Halftime tenured Associate Professor (Chargé de Cours), Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium 2016-present Professor, Erasmus Hospital, Université Libre de Bruxelles, Brussels, Belgium 2016-present Clinical Director (Directeur de Clinique), Division of Endocrinology, Erasmus Hospital, Brussels, Belgium 2 Curriculum vitae Miriam Cnop MEMBERSHIP IN PROFESSIONAL SOCIETIES American Diabetes Association (ADA) American Society for Biochemistry and Molecular Biology Belgian Association for the Study of Obesity Belgian Diabetes Association Belgian Endocrine Society The Endocrine Society (USA) European Association for the Study of Diabetes (EASD) European Association for the Study of Obesity International Association for the Study of Obesity Fellow of the Belgian American Educational Foundation SCIENTIFIC AWARDS AND SCHOLARSHIPS Graduation: First Prize of the Faculty Jury for the Best Medical Curriculum, 1995 Aspirant of the Belgian Fund for Scientific Research (FWO), 1995-1999 Selected among the 5 best abstracts for the Orbita Congress Speakers’ prize Belgium, 2000, with the lecture: ‘Dyslipidemia: a new risk factor for the development of diabetes mellitus type 2?’ Fellow of the Belgian American Educational Foundation, Belgium, 2000 Fellow of the D. Collen Research Foundation, Belgium, 2000 Fellow of the Hoover Foundation Brussels, Belgium, 2000 Fellow of the Medische Stichting Horlait-Dapsens, Belgium, 2000 Victor Lange Prize for Diabetes Research in Belgium, 2003 Prize from the Jean De Meyer Foundation for Research in Endocrinology, awarded by the Royal Academy of Science of Belgium, 2003 Novo Nordisk Prize for Diabetology, Belgium, 2004 Honorary Fellow of the Erasmus Foundation Brussels, Belgium, 2004 Fellow of the Belgian Fund for Medical Scientific Research (FRSM), 2005-2010 Young Investigator Award of the Belgian Endocrine Society, Brussels, Belgium, 2004 “Rising Star” of the European Association for the Study of Diabetes, 2005 Prize - Research Award from the Octave Dupont Foundation, awarded by the Royal Academy of Science of Belgium, 2005 Young Investigator Award of the National Ataxia Foundation, USA, 2007 Sanofi-Aventis Award in Diabetes, Belgium, 2007 GB Morgagni Young Investigator Award, awarded under the auspices of the School of Medicine of the University of Padua, Italy, 2010 Belgian Endocrine Society Annual Lecture Award, Belgium, 2010 Oskar Minkowski Prize of the European Association for the Study of Diabetes, 2013 Auguste Loubatières Prize of the French Diabetes Society, 2014 RESEARCH GRANTS European Foundation for the Study of Diabetes - Johnson & Johnson Type 2 Diabetes Research Grant (Co-applicant). Title: Molecular mechanisms of cell apoptosis induced by adipocyte-derived mediators in type 2 diabetes mellitus. Period: 2003-2005. Total amount of support: € 100,000. David & Alice Van Buuren Foundation Research Grant (Principal Investigator). Title: Molecular mechanisms of cell apoptosis in type 2 diabetes: role of free fatty acids and adipokines. Period: 2005. Total amount of support: € 13,000. European Foundation for the Study of Diabetes – Novo Nordisk Programme for Diabetes Research (Principal Investigator). Title: Endoplasmic reticulum stress: a putative cause of nutrient- and obesity-induced pancreatic -cell dysfunction and death in type 2 diabetes. Period: 2005-2006. Total amount of support: € 100,000. 3 Curriculum vitae Miriam Cnop Belgian Lipid Club Research Fellowship 2005 (Principal Investigator). Title: Free fatty acids are the effectors of nutrient- and obesity-induced -cell loss in type 2 diabetes via induction of endoplasmic reticulum stress. Period: 2006. Total amount of support: € 12,500. Research Award from the Octave Dupont Foundation, awarded by the Royal Academy of Science of Belgium (Principal Investigator). Title: Endoplasmic reticulum stress: a putative cause of nutrient- and obesity-induced pancreatic cell dysfunction and death in type 2 diabetes. Period: 2006-2007. Total amount of support: € 12,500. European Union FP6 Integrated Project (Co-applicant). Acronym: EURODIA. Title: Functional genomics of pancreatic cells and of tissues involved in control of the endocrine pancreas for prevention and treatment of type 2 diabetes. Period: 2006-2010. Total amount of support: € 416,000. Young Investigator Award of the National Ataxia Foundation USA (Principal Investigator). Title: Pathogenesis of impaired glucose tolerance and diabetes in Friedreich’s ataxia: contribution of insulin resistance and pancreatic beta cell dysfunction. Period: 2008-2009. Total amount of support: $ 100,000. European Foundation for the Study of Diabetes – Lilly European Diabetes Research Programme (Principal Investigator). Title: Mitochondrial dysfunction in insulin resistance and pancreatic cell failure - role in the pathogenesis of diabetes in Friedreich’s ataxia. Period: 2009. Total amount of support: € 100,000. European Union FP7 Collaborative Project (Principal Investigator). Acronym: CEED3. Title: Collaborative European Effort to Develop Diabetes Diagnostics. Period: 2008-2012. Total amount of support: € 196,000. French Association for the Study of Diabetes - Alfediam (Principal Investigator). Title: The pathogenesis of diabetes in Friedreich's ataxia - combining patient studies and experimental transgenic models to identify novel therapies for frataxin deficiency. Period: 2009. Total amount of support: € 20,000. European Foundation for the Study of Diabetes – Lilly European Diabetes Research Programme (Principal Investigator). Title: Stress relief or anti-apoptotic defense? Mechanisms of GLP-1 protection against lipotoxic endoplasmic reticulum stress in pancreatic cells. Period: 2010. Total amount of support: € 100,000. Concerted Research Action (Actions de Recherche Concertée), Belgium (Principal Investigator). Title: Discovery of the molecular pathways regulating pancreatic
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