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Fy Sept Edition Kk Original FINAL-1 Ver 15 PRINT Sm.Cdr WRaPMarching towards a HIV/AIDS free- futureUp Walter In this issue Reed s Moving up with research studies 2 s DHIS in NMOD-USDOD Program 3 s Commmon Malaria 4 Program s JWARG in Nigeria 6 s Infectious diseases 10 Nigeria s And much more... NewsletterofUSDepartmentofDefenseWalterReedProgram-Nigeria Vol. 5, End of FY 16 Edition 2016 Newsletter of U.S. Department of Defense Walter Reed Program-Nigeria (DoD WRP-N) FOREWORD s the fiscal year comes to a bioresponse capability to challenges presented today. Aclose, the military to detect, provide surveillance The enduring military to military partnership reflects on a n d r e s p o n d t o f u t u r e military partnership between the past 12 months to look at infectious disease outbreaks Walter Reed and the Health our successes, challenges and that affect the military and the Implementation Programme way forward. communities in which they has a bright future and is poised serve. to continue to succeed in their The Walter Reed Program- ongoing and future missions, Nigeia (WRP-N) saw significant In missions all around the some of which are summarized growth in program activities country and sub-region, the in this newsletter. and added a new component, Nigerian military medical corps spearheaded by headquarters continues to respond to the call Thank you for your continued leadership, known as the Joint of duty, while the government support of our partnership. West African Research Group manages a significantly - Robbie Nelson (JWARG). In addtion to JWARG, reduced budget due to the Country Director the partnership is initiating a devaluation of the Naira, WRP-N second Ebola vaccine trial, and resulting from lower prices and a malaria slide bank protocol to production of crude oil. The enduring military to improve diagnosis, quality Notwithstanding, the NMOD military partnership between assurance and operational H e a l t h I m p l e m e n t a t i o n studies supported by PEPFAR. Programme (MOD HIP) remains Walter Reed and the Health an example of efficiency under Implementation Programme J WA R G f o c u s e s o n c o - a strong unity of command by has a bright future and is infections and scientific ensuring that the soldier and poised to continue to succeed information on program Nigeria can rely on a force that in their ongoing and future metrics preparing for a i s t a k i n g o n t h e m a ny missions. From left: Mr. Robert Nelson, WRP-N Country Director, Brig. Gen. NA Hussain, HIP Director; and Mr. John Bray, U.S. Consul General RESEARCH Moving up with Research Studies RV 456e Ebola Vaccine Research stage involves follow-up of all study A meeting with few study V 4 5 6 e P r o t o c o l i s a participants and administration of participants during the second Rrandomized, observer-blind, vaccine to those who had received phase initiation showed that they placebo-controlled, two-part, placebo at commencement of the were well, comfortable and happy phase 2 study to evaluate the study. to continue participating in the s a f e t y , t o l e r a b i l i t y a n d study. Immunogenicity of two prime- T h e 1 2 m o n t h s s t u d y i s boost regimens of the candidate investigating the safety and As the program moves towards prophylactic vaccines for Ebola immune response of African adults investigative discoveries in the Ad26.ZEBOV and MVA-BN-Filo to the Type 3-vectored Ebola Zaire area of public health, research (VAC5150EBL2003). vaccine. Nigeria is contributing studies are the tools which will 330 volunteers to the research help mitigate infectious diseases The objective of this study is to pool which is being conducted by outbreaks towards securing a assess the safety and tolerability of the Walter Reed Program-Nigeria. healthy global world. different vaccination schedules of Ad26.ZEBOV and MVA-BN-Filo Tracking Development of Malaria Slide vaccines and to evaluate its Tracking involves a continuous Bank for External Quality immune response to the Ebola follow-up of study participants who Assessment Training vaccine. These vaccines are have missed their appointment or he NMOD/USDOD Program has expected to stimulate the body's cannot be reached on phone. Tcommenced preparations for immune system and provide Since the successful close of the another research study. The aim of protection against infections with first phase of the Ebola vaccine this study is to determine the the Ebola virus. A total of 575 research study, the Community accuracy of the Malaria Rapid volunteers will be enrolled in this Engagement team of the Clinical Diagnostic Test (MRDT) currently study which will be conducted in Research Center has been on the used in public sector clinics and Nigeria, Kenya, Uganda, Tanzania, heels of study participants to hospitals. The study also aims to Mozambique and United States of locate them and track their develop a specimen bank of America. The Walter Reed general well-being. This is not an validated, fixed, stained and P r o g r a m - N i g e r i a ' s C l i n i c a l easy feat in this terrain where preserved blood smears for Research Centre in Abuja will addresses are not clearly defined training, testing, and quality enroll 50 healthy volunteers or allocated. By the end of the first a s s u r a n c e / a s s e s s m e n t o f including persons living with HIV. quarter of the year, all registered microscopic malaria diagnosis in participants for the vaccine study Nigeria. This study will be This is the second of the studies on had come for their scheduled conducted in six NMOD/USDOD Ebola vaccine to be conducted by month-6 visit and were unblinded Program sites and will enroll about the NMOD/USDOD Program as (in revelation of the type of vaccine 300 participants. par t of its effor ts toward administered to the study preparedness against infectious participants). disease outbreaks. The Ebola epidemic hit Nigeria in 2014 and the NMOD/USDOD Program has been at the fore-front to find lasting solutions to infectious disease outbreaks in the region and also to advance research studies. RV 429 Ebola Vaccine Research V 429 Protocol is a Phase 2, Rrandomized, observer-blind, placebo-controlled, multi-country, cross-over study which has entered i t s s e c o n d s t a g e o f implementation. This second 2 PINTEPEFRAVRIE:W CLINICAL District Health Information System (DHIS) IGA at Program Sites he NMOD-USDOD Program has The Program has since then he USDOD Walter Reed Tsuccessfully implemented adopted the use of the DHIS2 for TProgram- Nigeria and the Programme Health Information data management in the Program H e a l t h I m p l e m e n t a t i o n Management System (ProHIMS) and subsequently, data reporting Programme (DOD WRP-N/MOD- using DHIS2 in its Program sites. has become automated. Benefits HIP) has once again improved from this innovative venture health outcomes in its Program In a two-week training in May 2016, include: decreased transcription sites with the provision of items data officers and site managers from errors, improved reporting rates, that will generate income for all of the Program’s comprehensive and improved quality of program People Living with HIV (PLHIV) - and selected satellite sites were data. Income Generating Activities (IGA). trained on effective use of the DHIS2. In May 2016, USDOD WRP-N/MOD The DHIS2 was developed primarily Additionally, it has led to improved HIP procured office furniture for its to serve in the area of aggregating data management as site staff and supported sites and support group health information and data on a very Programme managers can now offices. These support groups large scale. DHIS 2 enables users to access data in real time and provide avenues for rehabilitating collect, manage and analyze observe important trends which aid and supporting clients to have a transactional, case-based data in decision making. s e n s e o f b e l o n g i n g a n d records. sustainability. 12 sites benefitted - Navy Lt. C. Eneja from this project aimed at improving the quality of clinical care given to its clients and ensure effective service delivery in the sites. Items donated include tables, chairs, bookshelves, fans and other equipment such as sewing machines and hair dryers which will improve the quality of services accessed by HIV patients at the facility. Program activities continue with monitoring and standardization of site activities through SIMS (Site Improvement Monitoring System) visits. - Dr. Ismail Lawal Esther Essien LABORATORY Equipment Update at DRL he NMOD/USDOD Program has degree centigrade, Tupgraded its equipment at the human samples can Defense Reference Laboratory Abuja b e s t o r e d a n d with a new Liquid Nitrogen Generator preserved for many (LN2) M280X2. This is another feat years. The LN2 has for the Program, as it is the first non- been installed and govermental organization to own and commissioned and provide this service in Nigeria. The will ser ve as a LN2 M280X2 is of a higher capacity in biorepository for all comparison to the existing ones military hospitals, (NL280). The plant has the capacity research facilities to generate 80 litres of liquid and beyond.
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