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We are proud to support Global Gathering Gala the Weizmann Institute of Science.                

and Distingushed Guests from the Scientific Community

         The Three Tenors from Israel

Saturday, February 7, 2009

Jubilee Plaza Dorothy Chandler Pavilion Grand Hall Science for the Benef it of Humanity

Louis and Cathy Rosenmayer Science for the Benef it of Humanity

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ScienceS i forf theh BBeneff iit off HHumanityi ScienceS i forf theh BBeneff iit off HHumanityi

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Chuck Lorre, honoree

or the past twenty years, F award-winning creator, executive producer and writer Chuck Lorre has conquered the entertainment industry with hit         shows like “Grace Under Fire,” he Three Tenors From Israel is a dazzling trio that has taken Israel and Europe by storm. International opera star Yevgeni Shapovalov formed the “Dharma & Greg,” “,” and T group in 2005 with his acclaimed operatic colleagues. Since their debut, they “,” as well as the number one have given over 200 sold-out performances in Israel and Europe. comedy on television, and three-year YEVGENI SHAPOVALOV, frequently called “The Golden Voice of Israel,” was born in Belarus and trained in Ukraine. In Israel, he studied with Tamar Rahum at People’s Choice Award winner, the Rubin Academy of Music in Tel Aviv. A recipient of the America-Israel Cultural “” and the series “.” A native of Long Foundation scholarship, Shapovalov has performed opera, classical and international folk music in such venues and with such companies as Carnegie Hall, the Opéra Island, Lorre recently received the Brandon Tartikoff Legacy Award from NATPE National de Paris, Opera and the Metropolitan Opera. for exhibiting extraordinary passion, leadership, independence and vision in the BORIS EROFEEV was born in the former Soviet Union, where he obtained the process of creating television programming and evoking the spirit of Brandon honor of a Distinguished Artist and performed in concerts and opera productions with leading companies and orchestras, touring extensively in Europe. Since Tartikoff’s generosity. American Screenwriters Association will also give Lorre the immigrating to Israel, Erofeev has established himself among the country’s leading David Angell Humanitarian Award for his charitable efforts at the Venice Family classical tenors, participating as principal soloist both on the concert stage and in many operas and oratorios. Mr. Erofeev performs regularly with the Israel Clinic. In March 2009, Lorre will be awarded with his Star on the Hollywood Philharmonic, Symphony Orchestra and other leading Israeli orchestras.

Walk of Fame for his life-long contribution to the Hollywood Community. VLADISLAV GORAY moved to Israel after a stellar career in his native Ukraine, where in 1993 he received his Ph.D in Voice from the State Odessa Conservatory of Music. Having toured extensively in Europe, Goray has amassed a variety of leading roles, and is a laureate of several prestigious vocal competitions. He is currently a soloist with the Israeli Opera and his powerful but round and pure lyric tenor has conquered audiences at home and abroad. Science for the Benef it of Humanity Science for the Benef it of Humanity

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Original Weizmann Institute Building Entrance Gate

        , located in Rehovot,             Israel, is a center of science and technology research and    is a community of dedicated people who share a graduate study. The Institute’s 2,600-strong community common vision in support of the Institute. The generous engages in basic and applied research addressing crucial assistance the Institute receives from individuals, founda- problems in medicine and health, energy, technology, tions, and corporations is vital for its future. Committee agriculture, and the environment. Outstanding young members show their devotion to the advancement of the scientists from around the world pursue advanced degrees Institute’s goals by becoming partners in the search for at the Weizmann Institute’s Feinberg Graduate School. answers to the most difficult challenges facing humanity. The discoveries and theories of Weizmann Institute scientists have had a major impact on the wider scientific community, as well as on the quality of life of millions of people worldwide.

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WEIZMANN INSTITUTE OF SCIENCE GALA DINNER CHAIRS Prof. Mandy Moross Ilene and Jeff Nathan PRESIDENT CHAIR, BOARD OF GOVERNORS Sondra and Tom Rykoff Vera and John Schwartz AMERICAN COMMITTEE FOR THE Lucienne and David Soleymani WEIZMANN INSTITUTE OF SCIENCE Lon Morton, Southern Regional Chair Lawrence S. Blumberg Pennie Abramson Dr. Albert Willner CHAIRMAN PRESIDENT PRESIDENT EMERITUS GALA DINNER COMMITTEE

HONORARY REGENTS Melinda & Leo Bunnin Marlene & Bruce Kanter Janet & David Polak Rudy Boschwitz Henry Kissinger Frank Press Pamela & Stanley Chais Robin & Andrew Katzenstein Lois Rosen Lester Crown Samuel Lewis Michael P. Schulhof Wrenn & Bill Chais Joyce Eisenberg Keefer & Mel Keefer Cathy & Lou Rosenmayer Daniel K. Inouye Paul A. Marks George P. Shultz Emily & Michael Chasalow Rebecca & David Kekst Jolie & Paul Schifino Max M. Kampelman Maxine F. Singer Joy & Rob Cohn Kristen & Jerry Klein Susan & Donald Schwarz Marshall S. Levin Jana & George Eshaghian Ellen & Harvey Knell Fela & David Shapell EXECUTIVE VICE PRESIDENT & CEO Marshall Ezralow Sherry Lansing & Jill & Aubrey Sharfman Judy & Jerry Felsenthal William Friedkin Andra & Philip Stein Harold L. Adler CHIEF OPERATING OFFICER Malsi Doyle & Mike Forman Katy & Gary Leff Mucci & Larry Taylor Myron Funk Gloria Lushing Dale & Dennis Weiss Michael F. Abidor Henry H. Pavony SENIOR VICE PRESIDENT SENIOR VICE PRESIDENT & CFO Elaine & Bram Goldsmith Padma & Rao Makineni Edna Weiss Davina & Russell Grossman Shideh & Dale Miller Fredda Weiss Lon Morton Harold Igdaloff Rocky & Lon Morton Ruth Ziegler REGIONAL CHAIR, SOUTHERN CALIFORNIA Aya & Eddy Jakobovits Nicole & Allan Mutchnik Laticia & Barry Ziskin Janis Rabin Susan & Dan Kane Annette & Ron Plotkin EXECUTIVE DIRECTOR, SOUTHERN CALIFORNIA Janis Rabin Bella Simon Cayne Carol Taylor Stephanie Horsley Executive Director Director of Development Program Coordinator Program Coordinator

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Tallie Z. Baram, M.D. Ph.D. Dr. Baram earned her Ph.D. at the Weizmann Institute of Science. She is a Professor in the Departments of Pediatrics, Anatomy/Neurobiology and Neurology at the University of California, Irvine, where she holds the Danette Shepard endowed chair in Neurological Sciences.

Keith Black, M.D. Dr. Black is Chairman of the Dept. of Neurosurgery and Director of the Maxine Dunitz Neurosurgical Institute at Cedars- Sinai Medical Center. Prior to joining Cedars-Sinai, Dr. Black was a Professor of Neurosurgery at the University of California, for 10 years and was Head of the UCLA Comprehensive Brain Tumor Program. His collaborators include Prof. Michal Schwartz, of the Weizmann Institute’s Neurobiology Department, who is currently leading neuroimmunology research at the Dept. of Neurosurgery at Cedars-Sinai.

Prof. Eytan Domany Prof. Domany is a member of the Department of Physics of Complex Systems at the Weizmann Institute of Science, where he is the incumbent of the Henry J. Leir Professorial Chair. He is head of the Kahn Family Center for Systems Biology of the Human Cell.

Prof. Michael Eisenbach Prof. Eisenbach joined the staff of the Weizmann Institute of Science as a Postdoctoral Fellow and as a Scientist in the Department of Membrane Research. He presently works in the Department of Biological Chemistry. Prof. Eisenbach is the incumbent of the Jack and Simon Djanogly Professorial Chair in Biochemistry.

ScienceS i forfh the BBeneff iit off HHumanityi Our Distinguished Guests

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Prof. Richard S. Ellis Dr. Avishay Gal-Yam

Prof. Ellis is the Steele Professor of Astronomy at CalTech. He has Dr. Gal-Yam is a Senior Scientist at the Benoziyo Center for collaborated in cosmology with Professor Eli Waxman, Director of Astrophysics at the Weizmann Institute of Science. He earned The Benoziyo Center for Astrophysics at the Weizmann Institute of his Ph.D. from the School of Physics and Astronomy at Tel-Aviv Science, and in supernova studies with Dr. Avishay Gal-Yam, Senior University. He has been Visiting Associate, Postdoctoral Scholar, Scientist at the Benoziyo Center for Astrophysics. and Hubble Postdoctoral Fellow at CalTech.

Dr. Michael Elowitz Dr. Elowitz is Assistant Professor of Biology and Applied Physics at Caltech. He earned his Ph.D. from Princeton University and his B.A. from the University of California. He has collaborated with Prof. Uri Prof. Alexander Groisman Alon of the Weizmann Institute’s Dept. of Molecular Cell Biology. Prof. Groisman earned both his M.S. and Ph.D. from the Feinberg Graduate School at the Weizmann Institute of Science. He is currently Professor of Physics at the University of California, San Diego. He has collaborated with Prof. Victor Steinberg, the Harry de Jur Professor of Physics in the Weizmann Institute’s Dr. Gerald Estrin Dept. of Physics of Complex Systems. Dr. Estrin served as research engineer in the von Neumann group at the Institute for Advanced Studies, Princeton, NJ from 1950-56. In 1954-55, he was Director of the Electronic Computer Project at the Weizmann Institute of Science in Israel where he led the development of WEIZAC, the first large-scale electronic computer outside of the Prof. Haim Harari or Western Europe. He is a member of the Board of At the age of 26, Prof. Harari became a tenured professor at the Governors of the Weizmann Institute of Science. Weizmann Institute, the youngest ever, serving as the Annenberg Professor of High Energy Physics. He served as president of the Weizmann Institute from 1988 to 2001. During his presidency, the Institute entered numerous new scientific fields, built dozens of new Dr. Thelma Estrin buildings, raised more than one billion dollars in philanthropic funds, hired more than half of its current tenured professors and became Dr. Estrin was a principal member of the engineering group one of the highest royalty-earning academic organizations in the working on WEIZAC at the Weizmann Institute of Science. She world. He made several major contributions to and joined the UCLA Brain Research Institute in 1960 and founded was the first to synthesize the full standard model of six and its Data Processing Laboratory in 1970. She is a Fellow of six in its present form. IEEE, AAAS, SWE, and the American Institute of Medical and Biological Engineering. Our Distinguished Guests Our Distinguished Guests

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Prof. Alan J. Heeger Richard M. Karp, Ph.D. Prof. Heeger is the recipient of the 2000 Nobel Prize in Chemistry. Dr. Karp is a University Professor at the University of California, He earned a Ph.D. in physics from the University of California, Berkeley in the Department of Electrical Engineering and Computer Berkeley and a B.S. in physics and mathematics from the University Sciences with additional appointments in Mathematics, Bioengi- of Nebraska. He is Professor of Physics and Professor of Materials at neering and Operations Research. He received an honorary doctorate the University of California, Santa Barbara. from the Weizmann Institute of Science and is a member of the Board of Governors of the Institute. He is the recipient of the US National Medal of Science, the Kyoto Prize, and the Turing Award. He has had many interactions with Weizmann Institute computer science faculty, including David Harel, Amir Pnueli, Shafi Goldwasser, and Oded Goldreich. He earned his Ph.D. from Harvard University. Aya Jakobovits, Ph.D. Dr. Jakobovits earned her Ph.D. in Life Sciences and her M.Sc. in David Kleinfeld, Ph.D. Chemistry from the Weizmann Institute of Science. Dr. Jakobovits is Executive Vice President and Head of Research and Development at Dr. Kleinfeld is a Professor of Physics at the University of California, Agensys, a subsidiary of Astellas Pharmaceuticals, Inc. Dr. Jakobovits San Diego. His association with the Weizmann Institute includes has authored more than 50 scientific publications and is an inventor collaborations with Prof. Ehud Ahissar of the Neurobiology on over 80 patents. Department and Prof. Zvi Kam of the Molecular Cell Biology Department. He is the recipient of the NIH EUREKA award for vascular studies.

Edward Jakobovits, Ph.D. Prof. Douglas C. Leonard Dr. Jakobovits earned his Ph.D. in Genetics from the Feinberg Dr. Leonard is an Assistant Professor of Astronomy at San Diego Graduate School at the Weizmann Institute of Science. He is State University. He was a National Science Foundation Astronomy President of SciWeb, an Internet-based information and and Astrophysics Postdoctoral Fellow at CalTech. He collaborates communication service for life science professionals. with Dr. Avishay Gal-Yam, Senior Scientist at the Benoziyo Center for Astrophysics at the Weizmann Institute of Science.

Our Distinguished Guests Our Distinguished Guests

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Jay A. Levy, M.D. Sergio Peisajovich, Ph.D. Dr. Levy is a Professor in the Department of Medicine and Dr. Peisajovich earned his Ph.D. from the Feinberg Graduate School Research Associate at the Cancer Research Institute at the at the Weizmann Institute of Science. He is a Postdoctoral Fellow University of California School of Medicine, San Francisco. He in the Department of Cellular and Molecular Pharmacology at the collaborates with Prof. Nechama Haran-Ghera of the Weizmann University of California, San Francisco, where he was the recipient of Institute’s Immunology Department and Dr. Avi Levy of the the 2008 UCSF Postdoctoral Dean’s Prize. Weizmann Institute’s Plant Sciences Department.

Prof. Rudolph A. Marcus Fyl Pincus Dr. Marcus is the recipient of the 1992 Nobel Prize in Chemistry, the Dr. Philip Pincus is a Professor of Physics and Materials at Wolf Prize in Chemistry (1985) and the National Medal of Science the University of California, Santa Barbara. In addition to a (1989). He has been on the faculty of the Polytechnic Institute of long-time collaboration with Prof. Sam Safran of the Materials & Brooklyn and the University of Illinois, and in 1978 joined the faculty Interfaces Department at the Weizmann Institute of Science, of CalTech as Arthur Amos Noyes Professor of Chemistry. he has also collaborated with another member of the same department, Prof. Jacob Klein.

Roy Mukamel, Ph.D. Prof. Yoram Salomon Dr. Mukamel earned his Ph.D. from the Feinberg Graduate School Prof. Salomon spent three years as a Postdoctoral Fellow at the at the Weizmann Institute of Science. He is currently a Postdoctoral National Institutes of Health in Bethesda, MD, after which he Fellow at the University of California, Los Angeles and continues joined the Weizmann Institute’s Department of Hormone Research to collaborate with Prof. Rafael Malach, his Ph.D. supervisor at the in 1975. His Institute duties over the years have included serving as Weizmann Institute. chairman of the Department of Hormone Research and as Head of the Scientific Council. Prof. Salomon is currently a member of the Department of Biological Regulation, where he is the incumbent of the Charles W. and Tillie K. Lubin Chair of Hormone Research.

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Prof. Michal Schwartz Prof. Schwartz received her Ph.D. cum laude in chemical immunol- ogy from the Weizmann Institute of Science. She completed her postdoctoral studies at the Weizmann Institute and at the University of Michigan, returning to the Weizmann Institute in 1980. Prof. Schwartz is the incumbent of the Maurice and Ilse Katz Professorial Chair in Neuroimmunology. PROFESSOR SPONSORS

David Sprinzak, Ph.D. Dr. Sprinzak earned his Ph.D. from the Feinberg Graduate School at the Weizmann Institute of Science. He worked in a biotech startup in Israel that was based on an invention developed with Prof. Elisha Moses of the Weizmann Institute’s Physics Department. Dr. Sprinzak is a Postdoctoral Fellow in the Department of Biology at CalTech.

Prof. Daniel Zajfman Prof. Zajfman was born in Belgium and moved to Israel in 1979. He received a B.Sc. and a Ph.D. from the Technion – Israel Institute of Technology in Haifa, Israel, in atomic physics. After working as a consultant for Elscint in Haifa, Prof. Zajfman spent two years at the Argonne National Laboratory, near Chicago, as a postdoctoral fellow. He returned to Israel in 1991 and joined the staff of the Weizmann Institute’s Department of Particle Physics as a senior scientist. Since March 2001, he has been an external member of the Max Planck Sussman Environmental Building Institute of Nuclear Physics in Heidelberg, Germany, and in 2005, he was appointed director of that institute. Prof. Zajfman was elected the tenth president of the Weizmann Institute, becoming, at 47, the youngest president the Institute has ever had.

Our Distinguished Guests Science for the Benef it of Humanity

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tackled the problem of succeeded in reversing the metastatic properties of bone marrow colon cancer; their research may be transplantation used as the foundation for drugs that between incompatible can specifically target colon cancer- donors by using causing genes. a hormone to mobilize bone marrow cells of leukemia patients and “bubble” children.

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Malsi Doyle & Michael Forman Myron Funk

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applied for nearly 750 patents conducted research that led to the development of Copaxone® over the last ten years. & Rebif®, two FDA-approved multiple sclerosis drugs. MS affects 2.5 million people worldwide.

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For over 25 years, we have seen firsthand the Elaine & Bram Goldsmith miracles produced by our brilliant researchers. Goldsmith Family Foundation Joyce Eisenberg-Keefer and Mel Keefer

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are investigating the use of Copaxone® in treating glaucoma, the leading cause of preventable blindness in the U.S.

Jubilee Plaza Science for the Benef it of Humanity Science for the Benef it of Humanity

Padma & Rao Makineni

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developed an FDA-approved technique called 3TP, which have developed a sensor that can detect tiny amounts is a non-invasive way to diagnose breast cancer. of a biological weapon or airborne toxin This technique can spare patients the pain and risk to help combat terrorism. of biopsies.

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We are proud to support the Weizmann Institute and the scientific research that benefits all mankind. Ilene & Jeff Nathan Janet & David Polak

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are developing new models that describe fluid flow and are conducting clinical trials on the use of photodynamic the movement of chemicals in rock formations therapy (PDT) to treat prostate cancer, and plan to near aquifers. This research may lead to apply PDT to other cancers. PDT uses non-toxic chlorophyll, improved management of activated with light, to directly attack the tumor. freshwater resources.

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Vera & John Schwartz Susan & Donald Schwarz

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developed new wheat varieties have developed a tool to map the human brain, which could dramatically improve the ability to diagnose that provide nearly a 40 percent autism and other neu higher yield, allowing for rol og ic greater wheat production a l d per growing area unit. i s o

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These varieties produce

better crops that are more resistant to diseases and natural damage.

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Edna Weiss Candice & Barak Vaughn Mickey & Edna Weiss Charitable Fund

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SCIENTIST SPONSORS

Belfer Biomedical Building Jubilee Plaza Science for the Benef it of Humanity

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discovered that stem cells in the bone marrow can transform into liver cells and help repair a damaged liver. The liver is the second most sought organ for transplantation in the U.S.

have increased their understanding of congenital heart disease by utilizing stem cells to study the formation of heart muscle cells.

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Katy & Gary Leff Dr. Pamela Kushner & Michael Ourieff

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discovered a gene in wild tomato plants that provides are researching a resistance against disease. method to turn trash into biofuel by

breaking down the

cellulose in plants, wood, and paper.

The presence of this gene may greatly decrease the need for spraying crops with pesticides or treating soil, which can cause environmental damage.

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Congratulations to the Weizmann Institute for their efforts. Sondra & Tom Rykoff The Simms/Mann Family Foundation

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have developed a model to determine the effects of soot and other aerosols on the environment. The findings may help both climate modelers and are studying the practicality of water desalination policy-makers to understand the true climatic using solar or . wind energy consequences of burning trees or sooty industrial fuels. 97 percent of the Earth’s water supply is too salty for drinking or irrigation.

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Mucci & Larry Taylor Dale & Dennis Weiss

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RESEARCHER SPONSORS

are working on a biological computer —built from DNA—that is so tiny that a trillion of them can fit in a test tube and perform a billion operations per second.

Arison Neuroscience Building

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Fredda Weiss Science for the Benef it of Humanity

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are developing a first-of-its-kind for amoebic vaccination developed several methods for dysentery. Amoeba-caused disease claims the lives of encrypting and decrypting information. This thousands yearly and sickens millions more, mainly in research led to the development of “smart cards” impoverished that limit satellite broadcast reception to paid subscribers. communities. The encryption technology is also used in financial and governmental communications worldwide.

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In honor of Bella Simon Cayne and in memory of Marcel and Clarisse Roman. Vera & Paul Guerin Debra Michel

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pioneered the use of

amniotic fluid for

prenatal diagnosis,

leading to the clinical

application of tesis cen . io n m

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With heartfelt support and tremendous admiration for the Weizmann Institute. Eden & Steven Romick

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developed a novel solution to the problem of parasitic weeds that ravage crops worldwide, particularly in Africa. An estimated 100 million farmers lose half their yield to these parasites.

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Lucienne & David Soleymani

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used porcine embryonic tissue to grow new, fully functional kidneys— a dramatic finding SCHOLAR SPONSORS that may offer diabetics and others a solution to the problem of scarce organs.

Science for the Benef it of Humanity Congratulations to our good , Lon and Rocky Morton. Leo and Melinda Bunnin Science for the Benef it of Humanity Bunnin Automotive Group

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discovered the structure of AChE (a brain enzyme). developed a blood test to screen for schizophrenia. Their research is helping pave the way for the design of The mental disorder, which affects more than anti-Alzheimer’s drugs. two million Americans, now is diagnosed only through behavioral methods.

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Aya & Eddy Jakobovits Kristen & Jerry Klein

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are developing a blood test to uncover

risk for lung cancer, the leading are using basic research into cancer . killer crystal formation to help them understand how anti-malaria drugs work. Malaria infects about 300 to 500 million people a year, killing one to three million.

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To Lon, with heartfelt pride and affection for all the years, work, Congratulations Lon & Rocky for your continued good work. and service you have given to the Weizmann Institute. Michael and Corie Koss Monty and Elise Morton

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are developing new ways to use the sun’s energy. The Institute is equipped with one of the world’s most advanced solar research facilities.

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Dear Jeff and Ilene, I admire your efforts for the Weizmann Institute. Steven Neu

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Our thanks and appreciation to those who helped make the evening a success. Tarzana Treatment Centers is proud to support the Producer/Director Artist Amy Shomer, Shomer Associates Adam Rabinowitz American Committee for the

Lead Stage Manager Dorothy Chandler Pavilion Weizmann Institute of Science. Angela Hartman Rob Carson Mark O’Donnell AV and Lighting Carter Dyal, Dyal Productions Three Tenors from Israel Carol Bresner Décor Maria Shclover BLISS EVENTS Lauri Gaffin Photography Danni Wilkins Bill Aron Thomas Wilkins Veronica Wilkins Stilt Walkers Silk Sisters Graphic Design Linda O’Hanlon, Straightline Communications

Also thank you to: Kate Brown, Nilda Concepcion, Carol Fusco, Ramona Garcea, Cayce Lepa, Jon A. Leslie, Jennifer Manning, Suzanne McCormack, Eileen Radway, Rebecca Ryder Neipris, Maxine Stern, Laura Tucker, Pam Wilson.

A special thank you to Stephanie Horsley for her talent, enthusiasm, and dedication in coordinating the Southern California Global Gathering Gala. Jubilee Plaza And an extra special thank you to Carol Taylor for her creativity, scientific knowledge and untiring commitment in overseeing the presentation of tonight’s scientific research. Science for the Benef it of Humanity Tarzana Treatment Centers Science for the Benef it of Humanity

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