ACTA SCIENTIFIC NUTRITIONAL HEALTH (ISSN:2582-1423) Volume 4 Issue 4 April 2020 Short Communication Could Antihistamines Help in the Treatment and Spread of COVID-19 Via Re-Modulating Cytokines and by Reducing Sneezing? 1 2 Suna Aydin and Suleyman Aydin * Received: March 20, 2020 1Department of Cardiovascular Surgery, Elazig Fethi Sekin City Hospital, Health Sci- Published: March 27, 2020 ence University, Elazig Campus, Turkey © All rights are reserved by Suna Aydin and 2Department of Medical Biochemistry and Clinical Biochemistry, Medical School, Firat Suleyman Aydin. University, Turkey *Corresponding Author: Suleyman Aydin, Department of Medical Biochemistry and Clinical Biochemistry, Medical School, Firat University, Turkey. E-mail:
[email protected] Keywords: COVID-19; Interferon-gamma; Antihistamine; Public Health; Cytokine Coronaviruses are a large family of viruses [1]. The latest mem- ber of this family is termed the SARS-Cov-2 which causes COVID-19 the virus (COVID-19). Antihistamines can exert indirect antiviral etc.) so producing more IFN-γ and controlling the replication of [2]. Outbreaks of SARS-Cov-2 are now pandemic, given the toll of effects on infected cells and neighboring cells and can control anti- infections worldwide and the Covid-19 associated death rate [3]. viral properties by modulating IL-1, IL-2, TNF, and especially IFN-γ. knowing what to do to control COVID-19. No vaccine is currently to an antihistamine supply may have strong antiviral effects for CO- All governments have been taken by surprise and have difficulty in The depletion of IL-10, and then the over production of IFN-γ due available against the virus.