DOCSLIB.ORG

Third Report on Chicken Genes and Chromosomes 2015 M

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Third Report on Chicken Genes and Chromosomes 2015 M Animal Science Publications Animal Science 8-2015 Third Report on Chicken Genes and Chromosomes 2015 M. Schmid University of Würzburg J. Smith The Roslin Institute and R(D)SVS D. W. Burt The Roslin Institute and R(D)SVS B. L. Aken European Bioinformatics Institute, EMBL P. B. Antin University of Arizona SeFoe nelloxtw pa thige fors aaddndition addal aitutionhorsal works at: http://lib.dr.iastate.edu/ans_pubs Part of the Agriculture Commons, Genetics and Genomics Commons, and the Poultry or Avian Science Commons The ompc lete bibliographic information for this item can be found at http://lib.dr.iastate.edu/ ans_pubs/175. For information on how to cite this item, please visit http://lib.dr.iastate.edu/ howtocite.html. This Article is brought to you for free and open access by the Animal Science at Iowa State University Digital Repository. It has been accepted for inclusion in Animal Science Publications by an authorized administrator of Iowa State University Digital Repository. For more information, please contact [email protected]. Third Report on Chicken Genes and Chromosomes 2015 Abstract Following on from the First Report on Chicken Genes and Chromosomes [Schmid et al., 2000] and the Second Report in 2005 [Schmid et al., 2005], we are pleased to publish this long-awaited Third Report on the latest developments in chicken genomics. The irF st Report highlighted the availability of genetic and physical maps, while the Second Report was published as the chicken genome sequence was released. This report comes at a time of huge technological advances (particularly in sequencing methodologies) which have allowed us to examine the chicken genome in detail not possible until now. This has also heralded an explosion in avian genomics, with the current availability of more than 48 bird genomes [Zhang G et al., 2014b; Eöry et al., 2015], with many more planned. Disciplines Agriculture | Animal Sciences | Genetics and Genomics | Poultry or Avian Science Comments This article is from Cytogenic and Genome Research 145 (2015): 78, doi:10.1159/000430927. Rights Works produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The onc tent of this document is not copyrighted. Authors M. Schmid, J. Smith, D. W. Burt, B. L. Aken, P. B. Antin, A. L. Archibald, C. Ashwell, P. J. Blackshear, C. Boschiero, C. T. Brown, S. C. Burgess, H. H. Cheng, W. Chow, D. J. Coble, A. Cooksey, R. P. M. A.. Crooijmans, J. Damas, R. V. N. Davis, D.-J. de Koning, M. E. Delany, T. Derrien, T. T. Desta, I. C Dunn, M. Dunn, H. Ellegren, L. Eöry, I. Erb, M. Farré, M. Fasold, D. Fleming, P. Flicek, K. E. Fowler, L. Frésard, D. P. Froman, V. Garceau, P. P. Gardner, A. A. Gheyas, D. K. Griffin, M. A. M. Groenen, T. Haaf, O. Hanotte, A. Hart, J. Häsler, S. B. Hedges, J. Hertel, K. Howe, A. Hubbard, D. A. Hume, P. Kaiser, D. Kedra, S. J. Kemp, C. Klopp, K. E. Kniel, R. Kuo, S. Lagarrigue, Susan J. Lamont, D. M. Larkin, R. A. Lawal, S. M. Markland, F. McCarthy, H. A. McCormack, M. C. McPherson, A. Motegi, S. A. Muljo, A. Münsterberg, R. Nag, I. Nanda, M. Neuberger, A. Nitsche, C. Notredame, H. Noyes, R. O'Connor, E. A. O'Hare, A. J. Oler, S. C. Ommeh, H. Pais, M. Persia, F. Pitel, L. Preeyanon, P. Prieto Barja, E. M. Pritchett, D. D. Rhoads, C. M. Robinson, M. N. Romanov, M. Rothschild, P.-F. Roux, C. J. Schmidt, A.-S. Schneider, M. G. Schwartz, S. M. Searle, M. A. Skinner, C. A. Smith, P. F. Stadler, T. E. Steeves, C. Steinlein, L. Sun, M. Takata, I. Ulitsky, Q. Wang, Y. Wang, W. C. Warren, J. M. D. Wood, D. Wragg, and H. Zhou This article is available at Iowa State University Digital Repository: http://lib.dr.iastate.edu/ans_pubs/175 Report Cytogenet Genome Res 2015;145:78–179 Published online: July 14, 2015 DOI: 10.1159/000430927 Third Report on Chicken Genes and Chromosomes 2015 Prepared by 1 3 3 5 26 3 Michael Schmid Jacqueline Smith David W. Burt Bronwen L. Aken Parker B. Antin Alan L. Archibald 29 30 48 31, 32 27 Chris Ashwell Perry J. Blackshear Clarissa Boschiero C. Titus Brown Shane C. Burgess 33 6 40 28 17 Hans H. Cheng William Chow Derrick J. Coble Amanda Cooksey Richard P.M.A. Crooijmans 8 34 18 36 20 10 Joana Damas Richard V.N. Davis Dirk-Jan de Koning Mary E. Delany Thomas Derrien Takele T. Desta 3 6 19 3 24 8 2 Ian C. Dunn Matthew Dunn Hans Ellegren Lél Eöry Ionas Erb Marta Farré Mario Fasold 40 5 11 22 38 3 Damarius Fleming Paul Flicek Katie E. Fowler Laure Frésard David P. Froman Valerie Garceau 51, 52 3 12 17 1 Paul P. Gardner Almas A. Gheyas Darren K. Griffin Martien A.M. Groenen Thomas Haaf 10 3, 13 7 39 2 6 35 Olivier Hanotte Alan Hart Julien Häsler S. Blair Hedges Jana Hertel Kerstin Howe Allen Hubbard 3 4 24 14 23 35 David A. Hume Pete Kaiser Darek Kedra Stephen J. Kemp Christophe Klopp Kalmia E. Kniel 3 21 40 8 10 Richard Kuo Sandrine Lagarrigue Susan J. Lamont Denis M. Larkin Raman A. Lawal 35 28 3 36 53 Sarah M. Markland Fiona McCarthy Heather A. McCormack Marla C. McPherson Akira Motegi 41 15 5 1 7 2 Stefan A. Muljo Andrea Münsterberg Rishi Nag Indrajit Nanda Michael Neuberger Anne Nitsche 24 14 12 43 42 Cedric Notredame Harry Noyes Rebecca O’Connor Elizabeth A. O’Hare Andrew J. Oler Sheila C. Ommeh49 Helio Pais16 Michael Persia44 Frédérique Pitel22 Likit Preeyanon31 Pablo Prieto Barja24 Elizabeth M. Pritchett35 Douglas D. Rhoads45 Charmaine M. Robinson37 Michael N. Romanov12 Max Rothschild40 Pierre-François Roux21 Carl J. Schmidt35 Alisa-Sophia Schneider1 Matthew G. Schwartz46 Steve M. Searle6 Michael A. Skinner9 Craig A. Smith50 Peter F. Stadler2 Tammy E. Steeves51 Claus Steinlein1 Liang Sun35 Minoru Takata54 Igor Ulitsky25 Qing Wang35 Ying Wang36 Wesley C. Warren27 Jonathan M.D. Wood6 David Wragg22 Huaijun Zhou36 1 2 Department of Human Genetics, University of Würzburg, Würzburg , and Bioinformatics Group, Department of Computer Science and 3 Interdisciplinary Centre for Bioinformatics, University of Leipzig, Leipzig , Germany; Division of Genetics and Genomics, The Roslin 4 5 Institute and R(D)SVS, and Division of Infection and Immunity, The Roslin Institute, University of Edinburgh, Edinburgh , European 6 7 Bioinformatics Institute, EMBL, and Wellcome Trust Sanger Institute, Hinxton, Medical Research Council Laboratory of Molecular Biology, 8 9 Cambridge , Department of Comparative Biomedical Sciences, Royal Veterinary College, University of London, and Section of Virology, 10 Department of Medicine, Imperial College London, London , School of Life Sciences, University of Nottingham, Nottingham , Supported by Biotechnology and Biological Sciences Research Council (BBSRC); USDA Correspondence to: Agriculture and Food Research Initiative Competitive Grant; NIH Intramural Research Michael Schmid Program of the National Institute of Allergy and Infectious Diseases; European Union Department of Human Genetics, University of Würzburg FP-7 project QUANTOMICS; Deutsche Forschungsgemeinschaft (DFG); Swiss National Biozentrum, Am Hubland Science Foundation; Lady Tata Memorial Trust; French ‘Agence Nationale de la Recher- DE–97074 Würzburg (Germany) che’ EpiBird; Intramural Research Program of the NIEHS, NIH; Department for Interna- E-Mail m.schmid @ biozentrum.uni-wuerzburg.de tional Development (DFID). Jacqueline Smith Division of Genetics and Genomics The Roslin Institute, University of Edinburgh Edinburgh EH25 9RG (UK) E-Mail jacqueline.smith @ roslin.ed.ac.uk © 2015 S. Karger AG, Basel David W. Burt 1424–8581/15/1452–0078$39.50/0 Division of Genetics and Genomics The Roslin Institute, University of Edinburgh E-Mail [email protected] Edinburgh EH25 9RG (UK) www.karger.com/cgr E-Mail dave.burt @ roslin.ed.ac.uk Downloaded by: Iowa State University 198.143.32.1 - 11/11/2015 11:02:55 PM 11 12 School of Human and Life Sciences, Canterbury Christ Church University, and School of Biosciences, University of Kent, Canterbury , 13 14 Biological Services, Royal Hallamshire Hospital, University of Sheffield, Sheffield , Institute of Integrative Biology, University of 15 16 Liverpool, Liverpool , School of Biological Sciences, University of East Anglia, Norwich , and Weatherall Institute of Molecular Medicine, 17 University of Oxford, John Radcliffe Hospital, Oxford , UK; Animal Breeding and Genomics Centre, Wageningen University, Wageningen , 18 19 The Netherlands; Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, and Department of 20 Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Uppsala , Sweden; Institut de Génétique et Développement de 21 22 23 Rennes, Université de Rennes1, and Equipe Génétique et Génomique, PEGASE, INRA, Rennes , GenPhySE, INRA, and Plateforme 24 Bioinformatique Toulouse Midi-Pyrénées, INRA, Biométrie et Intelligence Artificielle, Castanet-Tolosan , France; Comparative 25 Bioinformatics Group, Bioinformatics and Genomics Programme, Centre for Genomic Regulation, Barcelona , Spain; Department of 26 27 Biological Regulation, Weizmann Institute of Science, Rehovot , Israel; Department of Cellular and Molecular Medicine, College of 28 29 Agriculture and Life Sciences, and Department of Veterinary Science and Microbiology, University of Arizona, Tucson, Ariz. , Department 30 31 of Poultry Science, Raleigh, N.C. , Department of Biochemistry, Duke University School of Medicine, NIEHS, Durham, N.C. , Microbiology 32 33 and Molecular Genetics, Michigan State University, Computer Science and Engineering, Michigan State University, and Avian Disease 34 35 and Oncology Laboratory, USDA, ARS, East Lansing, Mich. , Department of Biology, University of Delaware, and Department of Animal 36 37 and Food Sciences, University of Delaware, Newark, Del. , Department of Animal Science, University of California, Davis, Calif. , Division 38 of Science and Environmental Policy, California State University Monterey Bay, Seaside, Calif. , Department of Animal and Rangeland 39 40 Sciences, Oregon State University, Corvallis, Oreg.
Load more

Recommended publications
  • In Cooper's the Leatherstocking Tales
    CONNECTING THE VANISHING FLORA, FAUNA AND ITS RELATION TO THE INDIAN REMOVAL POLICY AS SEEN IN COOPER’S THE LEATHERSTOCKING TALES Ceisy Nita Wuntu [email protected] English Department, Faculty of Languages and Arts, Manado State University, Indonesia Abstract: This study aims at connecting the vanishing flora, fauna and its Relation to the Indian removal policy in Cooper’s The Leatherstocking Tales. This research applies an American Studies’ interdisciplinary principle supplemented by the myth and symbol theory proposed by Henry Nash Smith. Smith claimed the importance of imaginative works in revealing American culture. He declared that the historical, anthropological and cultural, sociological, and ecological data as covered in this research can be equipped by data from imaginative works. Hence, in this research, those data are presented integratedly in their context of past and present. In this research, in order to highlight environmental matters in Cooper’s The Leatherstocking Tales, the analysis covers the data above that are integrated with the data revealed in The Leatherstocking Tales as a whole by employing the concept of ecocriticism. The spirit of the immigrants to have a better life in the new world, stimulated by its rich, lush and beautiful circumstances, in fact, is not an aim of a sustainable life. The desire to improve their life is not enough without using and treating its environment wisely as well as facing it with the environmental conservation paradigm. The spirit of doing the exploitation is a consequence of western humanism value. The reason of coming to America to avoid the population density as well as the competition of life cannot be attained when the immigrants experience the same population density and harsh competition as in their old world and when the beautiful nature disappears, the forests become cities, the tranquility becomes noisy and crowded, and the people experience the uncomfortable life that many kinds of conflict can follow.
    [Show full text]
  • MADAGASCAR: the Wonders of the “8Th Continent” a Tropical Birding Custom Trip
    MADAGASCAR: The Wonders of the “8th Continent” A Tropical Birding Custom Trip October 20—November 6, 2016 Guide: Ken Behrens All photos taken during this trip by Ken Behrens Annotated bird list by Jerry Connolly TOUR SUMMARY Madagascar has long been a core destination for Tropical Birding, and with the opening of a satellite office in the country several years ago, we further solidified our expertise in the “Eighth Continent.” This custom trip followed an itinerary similar to that of our main set-departure tour. Although this trip had a definite bird bias, it was really a general natural history tour. We took our time in observing and photographing whatever we could find, from lemurs to chameleons to bizarre invertebrates. Madagascar is rich in wonderful birds, and we enjoyed these to the fullest. But its mammals, reptiles, amphibians, and insects are just as wondrous and accessible, and a trip that ignored them would be sorely missing out. We also took time to enjoy the cultural riches of Madagascar, the small villages full of smiling children, the zebu carts which seem straight out of the Middle Ages, and the ingeniously engineered rice paddies. If you want to come to Madagascar and see it all… come with Tropical Birding! Madagascar is well known to pose some logistical challenges, especially in the form of the national airline Air Madagascar, but we enjoyed perfectly smooth sailing on this tour. We stayed in the most comfortable hotels available at each stop on the itinerary, including some that have just recently opened, and savored some remarkably good food, which many people rank as the best Madagascar Custom Tour October 20-November 6, 2016 they have ever had on any birding tour.
    [Show full text]
  • Hypopituitarism May Be an Additional Feature of SIM1 and POU3F2 Containing 6Q16 Deletions in Children with Early Onset Obesity
    Open Access Journal of Pediatric Endocrinology Case Report Hypopituitarism may be an Additional Feature of SIM1 and POU3F2 Containing 6q16 Deletions in Children with Early Onset Obesity Rutteman B1, De Rademaeker M2, Gies I1, Van den Bogaert A2, Zeevaert R1, Vanbesien J1 and De Abstract Schepper J1* Over the past decades, 6q16 deletions have become recognized as a 1Department of Pediatric Endocrinology, UZ Brussel, frequent cause of the Prader-Willi-like syndrome. Involvement of SIM1 in the Belgium deletion has been linked to the development of obesity. Although SIM1 together 2Department of Genetics, UZ Brussel, Belgium with POU3F2, which is located close to the SIM1 locus, are involved in pituitary *Corresponding author: De Schepper J, Department development and function, pituitary dysfunction has not been reported frequently of Pediatric Endocrinology, UZ Brussel, Belgium in cases of 6q16.1q16.3 deletion involving both genes. Here we report on a case of a girl with typical Prader-Willi-like symptoms including early-onset Received: December 23, 2016; Accepted: February 21, hyperphagic obesity, hypotonia, short hands and feet and neuro-psychomotor 2017; Published: February 22, 2017 development delay. Furthermore, she suffered from central diabetes insipidus, central hypothyroidism and hypocortisolism. Her genetic defect is a 6q16.1q16.3 deletion, including SIM1 and POU3F2. We recommend searching for a 6q16 deletion in children with early onset hyperphagic obesity associated with biological signs of hypopituitarism and/or polyuria-polydipsia syndrome. The finding of a combined SIM1 and POU3F2 deletion should prompt monitoring for the development of hypopituitarism, if not already present at diagnosis. Keywords: 6q16 deletion; SIM1; POU3F2; Prader-Willi-like syndrome; Hypopituitarism Introduction insipidus and of some specific pituitary hormone deficiencies in children with a combined SIM1 and POU3F2 deficiency.
    [Show full text]
  • Madagascar: the 8Th Continent with Naturalist Journeys & Caligo Ventures Nov
    Madagascar: The 8th Continent With Naturalist Journeys & Caligo Ventures Nov. 26 – Dec. 10, 2018 866.900.1146 800.426.7781 520.558.1146 [email protected] www.naturalistjourneys.com or find us on Facebook at Naturalist Journeys, LLC Naturalist Journeys, LLC / Caligo Ventures PO Box 16545 Portal, AZ 85632 PH: 520.558.1146 / 800.426.7781 Fax 650.471.7667 naturalistjourneys.com / caligo.com [email protected] / [email protected] Madagascar: The 8th Continent With Naturalist Journeys & Caligo Ventures Isolated from any continental landmass since the Cretaceous period, Madagascar has drifted through the Indian Ocean, following its own evolutionary course, having only five major terrestrial animal colonization events since the time of the dinosaurs. The result is an island where every land mammal is endemic, as are nearly half the bird species. Reptiles are well represented as well, like chameleons, and day and leaf-tailed geckos. The uniqueness of this island’s fauna makes it one of the world’s great destinations for the birdwatcher and naturalist, alike. Our tour features both birds and mammals. We focus on Madagascar’s most iconic and charismatic bird species (we hope to see over 95% of the endemics), as well as the Island's other oddities, like endearing lemurs and strikingly bizarre chameleons. We also focus on the Island’s geology and geography with resulting various habitats ― from the spiny forests of Ifaty with its towering baobabs and other-worldly Didierea octopus trees, to the verdant rainforests of Andasibe-Mantadia
    [Show full text]
  • Genetic Characterization of Tanzanian Indigenous Chickens in Relation to the Worldwide Spectrum of Chicken Diversity
    Charles Moses Lyimo (Autor) Genetic Characterization of Tanzanian Indigenous Chickens in Relation to the Worldwide Spectrum of Chicken Diversity https://cuvillier.de/de/shop/publications/6939 Copyright: Cuvillier Verlag, Inhaberin Annette Jentzsch-Cuvillier, Nonnenstieg 8, 37075 Göttingen, Germany Telefon: +49 (0)551 54724-0, E-Mail: [email protected], Website: https://cuvillier.de Chapter 1 CHAPTER ONE 1.0 General introduction 1 Dieses Werk ist copyrightgeschützt und darf in keiner Form vervielfältigt werden noch an Dritte weitergegeben werden. Es gilt nur für den persönlichen Gebrauch. Chapter 1 1.1. The United Republic of Tanzania The United Republic of Tanzania is located in the Eastern coast of Africa just south of the equator between longitude 29° and 41° East, Latitude 1° and 12° South. It also incorporates several offshore islands, including Unguja (Zanzibar), Pemba, and Mafia. The country's eastern border is formed by the Indian Ocean coastline of approximately 1,400 km long. It has land borders with Kenya and Uganda to the north; Rwanda, Burundi and Democratic Republic of Congo to the west; and Zambia, Malawi and Mozambique to the south. Tanzania is the world’s 31st largest country with a total area of 947,300 km2 including 885,800 km2 of the land surfaces and 61,500 km2 of inland water bodies. It has a territorial sea limit of 22 km (12 nautical miles). Tanzania has a population of 45 million people with the annual growth rate of 2.7 % (NBS, 2013). There are over 120 ethnic groups, each with its own language or dialect. Swahili is the common and officially spoken language in all of Tanzania.
    [Show full text]
  • Rapanui Fowl
    BREED FOCUS: RAPANUI FOWL By Christine Heinrichs and Kermit Blackwood (USA) All photos not individually credited are by either Michelle Tullis, Jeremy Yashar-Johnson, Martin Blendulf or Tamiym Lehoux Above: A View of the Monuments of Easter Island, Rapa Nui. Oil on panel, by William Hodges, 1870. On Easter Sunday, April 5, 1722, Dutch sea captain Jacob Roggeveen landed his ship the Tienhoven on an island the inhabitants, the Rapanui, called Te Pito o Te Henua, The Center of the World. Captain Roggeveen renamed it Easter Island. Right: Captain Jacob Roggeveen. By the time the Dutch arrived, Easter Island’s population was in decline. There were probably no more than about 2,000-3,000 people living on the island. Maximum population estimates of previous eras range from 4,000- 15,000. Theories differ as to the cause of their demise. Barbara A. West writes in the Encyclopedia of the Peoples of Asia and Oceania, “… the Rapanui experienced a tremendous upheaval in their social system brought about by a change in their island's ecology...” Jared Diamond (an American biogeographer) drew attention to the connection between ecological overexploitation and the downfall of society. In Easter Island we are describing a situation where wholesale ecological exploitation destroyed a civilization. They’d cut down every last trees making it impossible to so build seaworthy boats to sail away. As in other Polynesian cultures, the Rapanui people knew cannibalism. By the 18th century, the population of Easter Island were coping with staying warm from Antarctic winds in winter without sufficient clothing. Terry Hunt and Caro Lipo’s studies suggest that humans made permanent settlements on Easter Island around 1200 AD, and that the population never exceeded around 3,000 people.
    [Show full text]
  • MADAGASCAR: the Wonders of the “8Th Continent” a Tropical Birding Set Departure
    MADAGASCAR: The Wonders of the “8th Continent” A Tropical Birding Set Departure November 3—28, 2013 Guide: Ken Behrens All photos taken during this trip. All photos by Ken Behrens unless noted otherwise. TOUR SUMMARY Madagascar has long been a core destination for Tropical Birding, and with last year’s opening of a satellite office in the country, we have further solidified our expertise in the “Eighth Continent.” This was another highly successful set-departure tour to this special island. It included both the Northwestern Endemics Pre-Trip at the start and the Helmet Vanga extension to the Masoala Peninsula at the end. Although Madagascar poses some logistical challenges, especially in the form of the national airline Air Madagascar, we had no problems on this tour, not even a single delayed flight! The birding was great, with 196 species recorded, including almost all of the island’s endemic birds. As usual, the highlight was seeing all five of the incredible ground-rollers, from the roadrunner-like Long-tailed of the spiny forest to the wonderful rainforest-dwelling Scaly. There was a strong cast of vangas, including Helmet, Bernier’s, and Sickle-billed. In fact, we saw every member of the family save the mysterious Red-tailed Newtonia which is only regularly seen in the far south. As normal, the couas were also a favorite. From the shy and beautiful Red-breasted of Madagascar Set Departure Tour Nov. 3-28, 2013 the eastern rainforest to the huge Giant Coua of the dry western forest, we were looking for and at couas virtually every day! The bizarre mesites form a Malagasy endemic family, and we had superb extended views of all three members of the family.
    [Show full text]
  • Analysis of the Indacaterol-Regulated Transcriptome in Human Airway
    Supplemental material to this article can be found at: http://jpet.aspetjournals.org/content/suppl/2018/04/13/jpet.118.249292.DC1 1521-0103/366/1/220–236$35.00 https://doi.org/10.1124/jpet.118.249292 THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS J Pharmacol Exp Ther 366:220–236, July 2018 Copyright ª 2018 by The American Society for Pharmacology and Experimental Therapeutics Analysis of the Indacaterol-Regulated Transcriptome in Human Airway Epithelial Cells Implicates Gene Expression Changes in the s Adverse and Therapeutic Effects of b2-Adrenoceptor Agonists Dong Yan, Omar Hamed, Taruna Joshi,1 Mahmoud M. Mostafa, Kyla C. Jamieson, Radhika Joshi, Robert Newton, and Mark A. Giembycz Departments of Physiology and Pharmacology (D.Y., O.H., T.J., K.C.J., R.J., M.A.G.) and Cell Biology and Anatomy (M.M.M., R.N.), Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada Received March 22, 2018; accepted April 11, 2018 Downloaded from ABSTRACT The contribution of gene expression changes to the adverse and activity, and positive regulation of neutrophil chemotaxis. The therapeutic effects of b2-adrenoceptor agonists in asthma was general enriched GO term extracellular space was also associ- investigated using human airway epithelial cells as a therapeu- ated with indacaterol-induced genes, and many of those, in- tically relevant target. Operational model-fitting established that cluding CRISPLD2, DMBT1, GAS1, and SOCS3, have putative jpet.aspetjournals.org the long-acting b2-adrenoceptor agonists (LABA) indacaterol, anti-inflammatory, antibacterial, and/or antiviral activity. Numer- salmeterol, formoterol, and picumeterol were full agonists on ous indacaterol-regulated genes were also induced or repressed BEAS-2B cells transfected with a cAMP-response element in BEAS-2B cells and human primary bronchial epithelial cells by reporter but differed in efficacy (indacaterol $ formoterol .
    [Show full text]
  • Mousebirds Tle Focus Has Been Placed Upon Them
    at all, in private aviculture, and only a few zoos have them in their col1ec­ tions. According to the ISIS report of September 1998, Red-hacks are not to be found in any USA collections. This is unfortunate as all six species have been imported in the past although lit­ Mousebirds tle focus has been placed upon them. Hopeful1y this will change in the for the New Millennium upcoming years. Speckled Mousebirds by Kateri J. Davis, Sacramento, CA Speckled Mousebirds Colius striatus, also known as Bar-breasted or Striated, are the most common mousebirds in crops and frequent village gardens. USA private and zoological aviculture he word is slowly spreading; They are considered a pest bird by today. There are 17 subspecies, differ­ mousebirds make great many Africans and destroyed as such. ing mainly in color of the legs, eyes, T aviary birds and, surprising­ Luckily, so far none of the mousebird throat, and cheek patches or ear ly, great household pets. Although still species are endangered or listed on coverts. They have reddish brown body generally unknown, they are the up­ CITES even though some of them have plumage with dark barrings and a very and-coming pet bird of the new mil­ naturally small ranges. wide, long, stiff tail. Their feathering is lennium. They share many ofthe qual­ Mousebirds are not closely related to soft and easily damaged. They have a ities ofsmall pet parrots, but lack many any other bird species, although they soft chattering cal1 and are the most of their vices, which helps explain share traits with parrots.
    [Show full text]
  • Appendix 2. Significantly Differentially Regulated Genes in Term Compared with Second Trimester Amniotic Fluid Supernatant
    Appendix 2. Significantly Differentially Regulated Genes in Term Compared With Second Trimester Amniotic Fluid Supernatant Fold Change in term vs second trimester Amniotic Affymetrix Duplicate Fluid Probe ID probes Symbol Entrez Gene Name 1019.9 217059_at D MUC7 mucin 7, secreted 424.5 211735_x_at D SFTPC surfactant protein C 416.2 206835_at STATH statherin 363.4 214387_x_at D SFTPC surfactant protein C 295.5 205982_x_at D SFTPC surfactant protein C 288.7 1553454_at RPTN repetin solute carrier family 34 (sodium 251.3 204124_at SLC34A2 phosphate), member 2 238.9 206786_at HTN3 histatin 3 161.5 220191_at GKN1 gastrokine 1 152.7 223678_s_at D SFTPA2 surfactant protein A2 130.9 207430_s_at D MSMB microseminoprotein, beta- 99.0 214199_at SFTPD surfactant protein D major histocompatibility complex, class II, 96.5 210982_s_at D HLA-DRA DR alpha 96.5 221133_s_at D CLDN18 claudin 18 94.4 238222_at GKN2 gastrokine 2 93.7 1557961_s_at D LOC100127983 uncharacterized LOC100127983 93.1 229584_at LRRK2 leucine-rich repeat kinase 2 HOXD cluster antisense RNA 1 (non- 88.6 242042_s_at D HOXD-AS1 protein coding) 86.0 205569_at LAMP3 lysosomal-associated membrane protein 3 85.4 232698_at BPIFB2 BPI fold containing family B, member 2 84.4 205979_at SCGB2A1 secretoglobin, family 2A, member 1 84.3 230469_at RTKN2 rhotekin 2 82.2 204130_at HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 81.9 222242_s_at KLK5 kallikrein-related peptidase 5 77.0 237281_at AKAP14 A kinase (PRKA) anchor protein 14 76.7 1553602_at MUCL1 mucin-like 1 76.3 216359_at D MUC7 mucin 7,
    [Show full text]
  • Birds of Madagascar and Their Conservation
    Birds of Madagascar and Their Conservation byMichael S. Putnam Department ofZoology University of Wisconsin tl Madison, Wisconsin I 100 plus Ecstatic Testimonials Striding up a steep hillside with the Council for Bird Preservation (Collar loud whisper of a rushing stream in and Stuart, 1985), 28 species of Warm, nurturing foods. the background, I stepped into a Malagasy birds are threatened and 14 mist-net lane I had cut a week before. species are considered as near­ Cook monthly, As I entered the clearing, a medium­ threatened. These species represent freeze in packets, sized brown bird squawked and flew between one-fifth and one-third of off from eye-level. Carefully search­ the island's endemic bird species. serve in seconds. ing the nearby vegetation, I became one of a lucky handful of foreigners The primary threats to Madagas­ At fine stores, orcall... to ever find a nest of the Brown car's birds today, habitat loss and Mesite (Mesitornis unicolor), a rare overhunting, have already eliminated 1(800) BIRD YUM forest-dwelling relative of rails. The many unique Malagasy creatures. 1 (800) 247-3986 large egg, delicately colored in sal­ Since people first arrived on Mada­ mon with liver-colored spots, rested gascar 1500 to 2000 years ago, much 13330 Bessemer Street precariously in a frail, dove-like nest of the island has been deforested, Van Nuys, CA91401-3000 positioned at the end of a sloping leaving the red lateritic soil exposed (818) 997-0598 sapling. This encounter with the and eroding, with little chance for Brown Mesite is just one of many forest regeneration.
    [Show full text]
  • Karla Alejandra Vizcarra Zevallos Análise Da Função De Genes
    Karla Alejandra Vizcarra Zevallos Análise da função de genes candidatos à manutenção da inativação do cromossomo X em humanos Dissertação apresentada ao Pro- grama de Pós‐Graduação Inter- unidades em Biotecnologia USP/ Instituto Butantan/ IPT, para obtenção do Título de Mestre em Ciências. São Paulo 2017 Karla Alejandra Vizcarra Zevallos Análise da função de genes candidatos à manutenção da inativação do cromossomo X em humanos Dissertação apresentada ao Pro- grama de Pós‐Graduação Inter- unidades em Biotecnologia do Instituto de Ciências Biomédicas USP/ Instituto Butantan/ IPT, para obtenção do Título de Mestre em Ciências. Área de concentração: Biotecnologia Orientadora: Profa. Dra. Lygia da Veiga Pereira Carramaschi Versão corrigida. A versão original eletrônica encontra-se disponível tanto na Biblioteca do ICB quanto na Biblioteca Digital de Teses e Dissertações da USP (BDTD) São Paulo 2017 UNIVERSIDADE DE SÃO PAULO Programa de Pós-Graduação Interunidades em Biotecnologia Universidade de São Paulo, Instituto Butantan, Instituto de Pesquisas Tecnológicas Candidato(a): Karla Alejandra Vizcarra Zevallos Título da Dissertação: Análise da função de genes candidatos à manutenção da inativação do cromossomo X em humanos Orientador: Profa. Dra. Lygia da Veiga Pereira Carramaschi A Comissão Julgadora dos trabalhos de Defesa da Dissertação de Mestrado, em sessão pública realizada a ........./......../.........., considerou o(a) candidato(a): ( ) Aprovado(a) ( ) Reprovado(a) Examinador(a): Assinatura: ..............................................................................
    [Show full text]