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Mothers in Science
The aim of this book is to illustrate, graphically, that it is perfectly possible to combine a successful and fulfilling career in research science with motherhood, and that there are no rules about how to do this. On each page you will find a timeline showing on one side, the career path of a research group leader in academic science, and on the other side, important events in her family life. Each contributor has also provided a brief text about their research and about how they have combined their career and family commitments. This project was funded by a Rosalind Franklin Award from the Royal Society 1 Foreword It is well known that women are under-represented in careers in These rules are part of a much wider mythology among scientists of science. In academia, considerable attention has been focused on the both genders at the PhD and post-doctoral stages in their careers. paucity of women at lecturer level, and the even more lamentable The myths bubble up from the combination of two aspects of the state of affairs at more senior levels. The academic career path has academic science environment. First, a quick look at the numbers a long apprenticeship. Typically there is an undergraduate degree, immediately shows that there are far fewer lectureship positions followed by a PhD, then some post-doctoral research contracts and than qualified candidates to fill them. Second, the mentors of early research fellowships, and then finally a more stable lectureship or career researchers are academic scientists who have successfully permanent research leader position, with promotion on up the made the transition to lectureships and beyond. -
Start-Up Company Networking Event 31St March 2021 (Wednesday) 1800 – 2000 Online (MS Teams)
Start-up company networking event 31st March 2021 (Wednesday) 1800 – 2000 Online (MS Teams) IChemE start-up company networking event Aims: Event details: • Build a community of chem-eng- • Anticipated participants: related start-ups for sharing • 13 start-ups information and experience • 1 government grant expert • ~20 IChemE members (spectators) • Inspire students/researchers about the application of chem eng knowledge and possible career paths Schedule • 1800 – 1830: Introduction by start-up representatives • 3 min each (10 start-ups: CMCL Innovations / Manchester Biogel / Octeract / Carbon Sink LLC / Accelerated Materials / Dye Recycle / Olwg / Nanomox / Solveteq / Greenr) • 1830 – 1910: Talks by Professor Nigel Brandon, Mr Phil Caldwell & Dr David Hodgson • 10 min each --- > start-up journey + key learning points • 10 min Q & A for all three speakers • 1910 – 1930: Talk by Dr Mat Westergreen-Thorne • 10 min --- > application of government grants • 10 min Q & A • 1930 – 2000: Panel discussions • Topics: • Personal development for start-up founders with technical background • Early-stage development: common mistakes, major milestones, resources available • Website: https://www.rfcpower.com/ Prof. Nigel Brandon (Director & co-founder) • Founded: 2017 • Product: Novel hydrogen-manganese reversible fuel • https://www.imperial.ac.uk/people/n.brandon cell for grid scale energy storage. • Email: [email protected] • RFC Power specializes in developing novel flow • Dean of the Faculty of Engineering and Chair in battery chemistries for energy storage systems. The Sustainable Development in Energy, Imperial College company was spun out from Imperial College’s London. Departments of Earth Science & Engineering and Chemistry in 2017, underpinned by a number of • BSc(Eng) in Minerals Technology and PhD in scientific breakthroughs and patents from the labs of electrochemical engineering from Imperial College Nigel Brandon, Anthony Kucernak, Javier Rubio Garcia London, followed by a 14 year research career in and Vladimir Yufit over the prior 8 years. -
Designing Ionic-Complementary
DESIGNING IONIC-COMPLEMENTARY HYDROGELS FOR BONE TISSUE REPAIR A thesis submitted to the University of Manchester for the degree of Doctor of Philosophy (PhD) in the Faculty of Chemical Engineering and Analytical Science 2014 MSc. LUIS ALBERTO CASTILLO DIAZ School of Chemical Engineering and Analytical Science CONTENTS List of figures……………………………………………………………….................4 List of abbreviations…………………………………………………………….……..5 Declaration…………………………………………………………………………….8 Copyright………………………………………………………………………………9 Acknowledgements…………………………………………………………………..10 Thesis Structure……………………………………………………………….…..….11 Abstract………………………………………………………………………………12 Objectives of the thesis………………………………………………………………13 1 Chapter 1 - Introduction. Versatile peptide hydrogels for bone and dental tissue regeneration………………….…………………….………………………..…….….14 2 Chapter 2- Human osteoblasts within soft peptide hydrogels promote mineralisation in vitro…………………………………………………………………….….70 3 Chapter 3 - Functional peptide hydrogels for bone formation applications………..71 4 Chapter 4 - Osteogenic differentiation of human mesenchymal stem cells promotes mineralisation within an octa-peptide hydrogel……………………...…....99 5 Chapter 5- Materials and methods……………………….………………………129 5.1 Materials…………………………………………………………………….…..129 2 5.2 Methods…………………………………………………………………………130 5.3 References………………………………………………………………………139 6 Chapter 6 – Conclusions, outlook and recommendations for future work………..140 6.1 Conclusions……………..……………………………………………………....140 6.2 Outlook………………………………………………………………………….141 6.3 Recommendations -
The Jon Weaver Phd Prize 2014
Macro Group UK & Polymer Physics Group Bulletin No 82 July 2014 Number Page 82 1 July 2014 MACRO GROUP UK POLYMER PHYSICS GROUP BULLETIN INSIDE THIS ISSUE: Editorial Views from the Top 2 Welcome to the July edition of the Macro Group and PPG bulletin. This edition sees a change to the PPG bulletin officer. Steve Eichhorn is 3 stepping down from this role and is replaced by Anthony Higgins. The Committee members MacroGroup and PPG committees would like to thank Steve for all his editorial work over the last two years. Awards 4 As usual, this issue of the bulletin contains several reports on recent conferences, and we would like to remind students that bursaries are News 7 available to MacroGroup and PPG student members to help fund conference expenses (see p10 for details of MacroGroup bursaries and Competitions announcements 10 p11 for details of bursaries available to PPG student members). Of special note, is the availability of the DH Richards bursaries to postdoctoral researchers who are members of the MacroGroup. Bursaries & Conference Reports 10-14 We also have many notices of forthcoming meetings and we would like to highlight in particular the one day Careers in Polymer Science: Beyond Forthcoming Meetings 15-18 Academia event in October, aimed specifically at postgraduate students and post-docs considering non-academic career paths. This issue also sees the call for nominations for the PPG Founders’ PrizePrizePrize and the PPG/DPOLY exchange lectureship with deadlines in early September. Contributions for inclusion in the BUL- LETIN should be emailed (preferably) Thank you to everyone who has contributed an item to this newsletter. -
Macro Group Uk Polymer Physics Group Bulletin
Macro Group UK & Polymer Physics Group Bulletin No 87 February 2017 Number Page 87 1 February 2017 MACRO GROUP UK POLYMER PHYSICS GROUP BULLETIN INSIDE THIS ISSUE: Editorial Welcome to the February edition of the Macro Group and PPG Views from the Top 2-3 Bulletin. This issue sees some changes in the MGUK committee. Prof. Neil Committee Members 3 Cameron has been succeeded by Professor Cameron Alexander as the new Chairman, Professor Dave Adams has been succeeded by Dr Valeria Arrighi as the new secretary and Dr Peter Deakin has Awards 4-7 been succeeded by Dr Adam Limer as new the treasurer. We would like to congratulate all of them on their recent appointment and wish Competition Announcements 8-9 all the best to Neil, Dave and Peter. Congratulations as well, to Professor Ian Hamley (University of Bursaries & Conference Reports 10-15 Reading) and Dr Theoni Georgiou (Imperial College), the winners of the 2016 MGUK awards (page 7) and to Professor Mark Warner and Dr Andrew Parnell, the winners of the PPG Founders’ Prize and Forthcoming Meetings & Confer- 16-24 the PPG/DPOLY Exchange Lectureship respectively (page 5). ences As usual, a reminder to PhD students and postdoctoral researchers who are members of the Macro Group that D. H. Richards bursaries are available to help fund conference expenses (page 8). Bursaries of up to £300 for attendance at international conferences and visits to international facilities are also available from the IOP Early Career Researchers Fund. If you have been awarded your PhD in 2016, you may want to Contributions for inclusion in the consider The Jon Weaver PhD Prize, check on page 8 for the BULLETIN should be emailed eligibility criteria. -
Macro Group Uk Polymer Physics Group Bulletin
Macro Group UK & Polymer Physics Group Bulletin No 83 January 2015 Number Page 83 1 January 2015 MACRO GROUP UK POLYMER PHYSICS GROUP BULLETIN INSIDE THIS ISSUE: Editorial Happy New Year and welcome to the January 2015 edition of Views from the Top 2 the Macro Group and PPG bulletin. Firstly we congratulate our distinguished award winners. Professor Richard Jones (University of Sheffield) is the recipient Committee Members 3 of the 2015 PPG Founders’ Prize. He will be presented with the award and give the Founders’ lecture at the PPG biennial in Manchester in September of this year. Dr Paola Carbone (University Awards 4-9 of Manchester) has been selected as the DPOLY Exchange Lecturer. She will present her lecture at the March 2015 meeting of the News 10 American Physical Society in San Antonio, Texas. Further details regarding both awards and the meeting in Manchester are given inside this issue of the bulletin. We also congratulate Professor Competitions Announcements 11-12 Cameron Alexander (The University of Nottingham) and Dr Paul D. Topham (Aston University) winners of the 2014 Macro Group Bursaries & Meeting Reports 12-19 UK Medal and Macro Group UK Young Researchers Medal, respectively. We would like to remind PhD students and postdoctoral Forthcoming Meetings 20-29 researchers who are members of the Macro Group that D. H. Richards bursaries are available to help fund conference expenses. We would like to encourage current polymer physics PhD students, and also those who have recently completed their studies, to apply for the Ian Macmillan Ward Prize. Contributions for inclusion in the BUL- As well as the prize announcement, this issue includes an LETIN should be emailed (preferably) article describing Professor Ward’s contributions to polymer physics or sent to either: and the decision by the PPG committee to name the PhD student prize in his honour. -
2011-06-15-Mothers-In-Science.Pdf
The aim of this book is to illustrate, graphically, that it is perfectly possible to combine a successful and fulfilling career in research science with motherhood, and that there are no rules about how to do this. On each page you will find a timeline showing on one side, the career path of a research group leader in academic science, and on the other side, important events in her family life. Each contributor has also provided a brief text about their research and about how they have combined their career and family commitments. This project was funded by a Rosalind Franklin Award from the Royal Society 1 Foreword It is well known that women are under-represented in careers in These rules are part of a much wider mythology among scientists of science. In academia, considerable attention has been focused on the both genders at the PhD and post-doctoral stages in their careers. paucity of women at lecturer level, and the even more lamentable The myths bubble up from the combination of two aspects of the state of affairs at more senior levels. The academic career path has academic science environment. First, a quick look at the numbers a long apprenticeship. Typically there is an undergraduate degree, immediately shows that there are far fewer lectureship positions followed by a PhD, then some post-doctoral research contracts and than qualified candidates to fill them. Second, the mentors of early research fellowships, and then finally a more stable lectureship or career researchers are academic scientists who have successfully permanent research leader position, with promotion on up the made the transition to lectureships and beyond. -
Human Osteoblasts Within Soft Peptide Hydrogels Promote Mineralisation In
TEJ0010.1177/2041731414539344Journal of Tissue EngineeringCastillo et al. 539344research-article2014 Original Article Journal of Tissue Engineering Volume 5: 1–12 Human osteoblasts within soft peptide © The Author(s) 2014 DOI: 10.1177/2041731414539344 hydrogels promote mineralisation in vitro tej.sagepub.com Luis A Castillo Diaz1,2, Alberto Saiani2,3, Julie E Gough3 and Aline F Miller1,2 Abstract Biomaterials that provide three-dimensional support networks for the culture of cells are being developed for a wide range of tissue engineering applications including the regeneration of bone. This study explores the potential of the versatile ionic-complementary peptide, FEFEFKFK, for such a purpose as this peptide spontaneously self-assembles into β-sheet-rich fibres that subsequently self-associate to form self-supporting hydrogels. Via simple live/dead cell assays, we demonstrated that 3 wt% hydrogels were optimal for the support of osteoblast cells. We went on to show that these cells are not only viable within the three-dimensional hydrogel but they also proliferate and produce osteogenic key proteins, that is, they behave like in vivo bone cells, over the 14-day period explored here. The gel elasticity increased over time when cells were present – in comparison to a decrease in control samples – indicating the deposition of matrix throughout the peptide scaffold. Moreover, significant quantities of calcium phosphate were deposited. Collectively, these data demonstrate that ionic-complementary octapeptides offer a suitable three-dimensional environment for osteoblastic cell function. Keywords Scaffold, peptide hydrogel, osteoblast cells, bone formation, mechanical properties Received: 25 February 2014; accepted: 2 May 2014 Introduction The majority of work within cell biology over the past These peptide-based hydrogels are typically fabricated few decades has been carried out in vitro on two-dimen- from short amino acid sequences that spontaneously self- sional (2D) systems, such as tissue culture plastic (TCP).1 assemble into β-sheet- or α-helix-rich fibres. -
Journal of Tissue Engineering
Journal of Tissue Engineering http://tej.sagepub.com/ Human osteoblasts within soft peptide hydrogels promote mineralisation in vitro Luis A Castillo Diaz, Alberto Saiani, Julie E Gough and Aline F Miller J Tissue Eng 2014 5: DOI: 10.1177/2041731414539344 The online version of this article can be found at: http://tej.sagepub.com/content/5/2041731414539344 Published by: http://www.sagepublications.com On behalf of: Institute of Tissue Regeneration Engineering Additional services and information for Journal of Tissue Engineering can be found at: Email Alerts: http://tej.sagepub.com/cgi/alerts Subscriptions: http://tej.sagepub.com/subscriptions Reprints: http://www.sagepub.com/journalsReprints.nav Permissions: http://www.sagepub.com/journalsPermissions.nav Downloaded from tej.sagepub.com by guest on December 1, 2014 TEJ0010.1177/2041731414539344Journal of Tissue EngineeringCastillo et al. 539344research-article2014 Original Article Journal of Tissue Engineering Volume 5: 1–12 Human osteoblasts within soft peptide © The Author(s) 2014 DOI: 10.1177/2041731414539344 hydrogels promote mineralisation in vitro tej.sagepub.com Luis A Castillo Diaz1,2, Alberto Saiani2,3, Julie E Gough3 and Aline F Miller1,2 Abstract Biomaterials that provide three-dimensional support networks for the culture of cells are being developed for a wide range of tissue engineering applications including the regeneration of bone. This study explores the potential of the versatile ionic-complementary peptide, FEFEFKFK, for such a purpose as this peptide spontaneously self-assembles into -sheet-rich fibres that subsequently self-associate to form self-supporting hydrogels. Via simple live/dead cell assays, we demonstrated that 3 wt% hydrogels were optimal for the support of osteoblast cells. -
General Kofi A. Annan the United Nations United Nations Plaza
MASSACHUSETTS INSTITUTE OF TECHNOLOGY DEPARTMENT OF PHYSICS CAMBRIDGE, MASSACHUSETTS O2 1 39 October 10, 1997 HENRY W. KENDALL ROOM 2.4-51 4 (617) 253-7584 JULIUS A. STRATTON PROFESSOR OF PHYSICS Secretary- General Kofi A. Annan The United Nations United Nations Plaza . ..\ U New York City NY Dear Mr. Secretary-General: I have received your letter of October 1 , which you sent to me and my fellow Nobel laureates, inquiring whetHeTrwould, from time to time, provide advice and ideas so as to aid your organization in becoming more effective and responsive in its global tasks. I am grateful to be asked to support you and the United Nations for the contributions you can make to resolving the problems that now face the world are great ones. I would be pleased to help in whatever ways that I can. ~~ I have been involved in many of the issues that you deal with for many years, both as Chairman of the Union of Concerne., Scientists and, more recently, as an advisor to the World Bank. On several occasions I have participated in or initiated activities that brought together numbers of Nobel laureates to lend their voices in support of important international changes. -* . I include several examples of such activities: copies of documents, stemming from the . r work, that set out our views. I initiated the World Bank and the Union of Concerned Scientists' examples but responded to President Clinton's Round Table initiative. Again, my appreciation for your request;' I look forward to opportunities to contribute usefully. Sincerely yours ; Henry; W. -
Samuel Frederick Edwards: Founder of Modern Polymer and Soft Matter
RETROSPECTIVE RETROSPECTIVE Samuel Frederick Edwards: Founder of modern polymerandsoftmattertheory Nigel Goldenfelda,1 This year marks the 50th anniversary of the seminal renormalization group ideas (2). This approach would paper by Sam Edwards on the statistical mechanics of be refined in great detail by subsequent studies, allow- a single polymer chain in dilute solution, a paper that ing accurate computation of universal scaling functions in one stroke founded the modern quantitative un- governing the physical chemistry of all polymers in derstanding of polymer matter, and vaulted soft solution and providing excellent agreement with ex- condensed matter on to the stage of theoretical periment. de Gennes would be awarded the 1991 physics (1). Sir Samuel Frederick Edwards, universally Nobel Prize in physics for his many contributions to known as “Sam,” was a giant of theoretical physics; he soft matter, but many believed that Edwards’ contri- passed away in Cambridge, England on May 7, 2015. butions, so frequently linked with de Gennes’,de- The problem solved in his 1965 paper (1) addresses served similar recognition. the simplest question that one can ask at a fundamen- In establishing the deep connections between tal level about polymeric matter: given the number of quantum field theory and the configurations of monomers in a chain, how big is the polymer itself in a polymer chain, Edwards inaugurated a new and 3D space? It is also an extraordinarily difficult prob- sophisticated way of looking at matter that was not lem: a polymer chain is almost a random configuration simply point-like but extended. He was fond of telling in space, yet it has to respect the constraint that atoms prospective students that “polymers are their own cannot overlap, restricting the positions of the mono- Feynman diagrams,” a single sentence that both en- mers in a nonlocal way and generally resulting in tranced and bewildered the listener. -
Neutron Scattering from Polymers 3 CH07CH01-Higgins ARI 14 May 2016 9:6
CH07-FrontMatter ARI 14 May 2016 8:27 Access provided by University of Cincinnati on 02/03/17. For personal use only. Annu. Rev. Chem. Biomol. Eng. 2016.7:1-28. Downloaded from www.annualreviews.org CH07CH01-Higgins ARI 14 May 2016 9:6 ANNUAL REVIEWS Further Click here to view this article's online features: • Download figures as PPT slides • Navigate linked references • Download citations Neutron Scattering from • Explore related articles • Search keywords Polymers: Five Decades of Developing Possibilities J.S. Higgins Department of Chemical Engineering, Imperial College London, London SW7 2AZ, United Kingdom Annu. Rev. Chem. Biomol. Eng. 2016. 7:1–28 Keywords The Annual Review of Chemical and Biomolecular neutron scattering, polymer molecular dynamics, polymer blends, spinodal Engineering is online at chembioeng.annualreviews.org decomposition, polymer interfaces Access provided by University of Cincinnati on 02/03/17. For personal use only. This article’s doi: Annu. Rev. Chem. Biomol. Eng. 2016.7:1-28. Downloaded from www.annualreviews.org 10.1146/annurev-chembioeng-080615-034429 Abstract Copyright c 2016 by Annual Reviews. The first three decades of my research career closely map the development All rights reserved of neutron scattering techniques for the study of molecular behavior. At the same time, the theoretical understanding of organization and motion of polymer molecules, especially in the bulk state, was developing rapidly and providing many predictions crying out for experimental verification. Neu- tron scattering is an ideal technique for providing the necessary evidence. This autobiographical essay describes the applications by my research group and other collaborators of increasingly sophisticated neutron scattering tech- niques to observe and understand molecular behavior in polymeric materials.