Section B: Curriculum Vitae for Kim Sneppen

Section b: Curriculum Vitae for Kim Sneppen

Kim Sneppen, e-mail: [email protected], telf: +45 2875 5352 Born 8 January 1960 in Copenhagen, Denmark, Danish Nationality. Married with 4 children. Address: Ordrupdalvej 37, 2920 Charlottenlund, Denmark.

Positions: Member of Danish Royal Academy of Sciences since 2006. September 2005 — ...... : CenterDirector,ModelsofLife, November 2005 — ...... : Professor,NielsBohrInstitute. November 2002 —2005 ...... : ResearchProfessor,Nordita. August 2002 — ...... (on leave 1/11/2002-1/9/2005): Associate professor, NBI August 2001 — Aug. 2002 ...... : Professor,NTNU,Trondheim. September 1995 — July 2001 ...... :AssistantProfessor, NORDITA. September 1989 — Aug. 1995 : Post-doc/ visiting scientist at Nordita, Rockefeller univ., Princeton univ., Weizman Institute & NBI. May 1989 ...... : Lic. Scient. (PhDinNuclearPhysics), University of Copenhagen. September 1986 - Aug. 1989 ...... : PhD student NBI.

Editorial work: August 2014 — ...... DivisionalAssociated Editor, Physical Review Letters.

Awards: The Gold Medal of the University of Copenhagen, November 1986. Ole Rømer price from “Videnskabernes Selskab, Denmark”, october 1995.

Publications: ∼ 190 publications in internationally peer reviewed journals. ∼ 11000 citations, H-index 47 (google scholar). Papers with > 1000 citations in 3 different areas of science.

Books: “Physics in Biological Systems”, K. Sneppen & G. Zocchi, Cambridge University press 2005. “Models of Life”, by K. Sneppen, Cambridge University press 2014.

Teaching activity: Taught courses in classical mechanics (2001), complex systems (1995-1998), physics in biological systems (1999-2005), and physics of gene regulation (2006-2013).

Supervisor: Supervised 14 PhD students. Currently supervising 3. Supervised 8 post docs. Currently supervising 3. 3 former PhD’s and 2 former post docs are now tenured faculty.

Research Interests: Self organization. Competition and Diversity in living systems: Epigenetics, decision and computation by genetic networks. Ecosystem dynamics, sustainability and collapse. Phage biology and microbial diversity. Information processing in living and social systems. Sneppen Part BI DIVERSITY

10 years track record: 10 interesting publications during 2005-2014:

1) S. Krishna, M.H. Jensen, K. Sneppen. “Spiky oscillations in NF-kB signalling.” PNAS 103 10840 (2006).

2) I.B. Dodd, M.A. Micheelsen, K. Sneppen and G. Thon. “Theoretical Analysis of Epigenetic Cell Mem- ory by Nucleosome Modiﬁcation” Cell 129 813-822 (2007).

3) S. Krishna, S. Semsey, K. Sneppen. “Combinatorics of feedback in cellular uptake and metabolism of small molecules.” PNAS 104 20815 (2007).

4) G. Tiana, S. Krishna, S Pigolotti, M.H. Jensen, K. Sneppen. Oscillations and temporal signalling in cells. Physical biology, 4, R1 (2007).

5) S. Maslov, S. Krishna, T.Y. Pang, K. Sneppen. “Toolbox model of evolution of prokaryotic metabolic networks and their regulation.” PNAS 106, 9743 (2009) [Faculty 1000 list]

6) N. Mitarai, J.-A.M. Benjamin, S. Krishna, S. Semsey, Z.Csiszovszki, E. Masse, and K.Sneppen. “Dy- namic features of gene expression control by small regulatory RNAs.” PNAS 106, 10655 (2009) [Faculty 1000 list]

7) K. Sneppen, S. Krishna, S. Semsey “Simpliﬁed Models of Biological Networks.” Annual Review of Biophysics 39, 43 (2010)

8) J. Mathiesen, N. Mitarai, K. Sneppen, A. Trusina. “Ecosystems with mutually exclusive interactions self-organize to a state of high diversity.” Phys. Rev. Lett. 107, 188101 (2011)

9) A.K. Alsing and K. Sneppen. “Differentiation of developing olfactory neurons analysed in terms of cou- pled epigenetic landscapes.” Nucleic Acids Research 41, 4755-4764 (2013). [Faculty 1000 list].

10) J.O. Haerter, N. Mitarai, and K. Sneppen. “Phage and bacteria support mutual diversity in a narrowing staircase of coexistence.” The ISME Journal 10.103 (2014)

Major Research Monographs:

K. Sneppen and G. Zocchi. “Physics in Biological Regulation”, Cambridge University press (2005)

K. Sneppen. “Models of Life: Dynamics and Regulation in Biological Systems”, Cambridge University press (2014)

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Invitations to major conferences: Keynote speaker at “Nishinomia symposium”, Osaka 2005. Invited speaker in “Asian Transcription Assembly Meeting”, Kolkata 2006. Invited speaker at “American Physical Society”, Denver 2007. Invited speaker at “American Microbiology Meeting” Boston 2008. Invited speaker at “Microbial Genomics Conference”, Rocky Gap State park, USA 2009. Invited speaker at “Evolution of Cooperation”, Bloomington, USA 2010. Invited speaker at “Stochastic physics in biology”, Gordon congerence, Ventura, 2011. Keynote speaker at ICSB, Main international system biology conference, 2011. Keynote and opening speaker at ICSB, Main international system biology conference 2013. Keynote speaker at Netsci, Large international Network conference, 2013.

Main Organizer of the following Workshops/Conferences/Summer schools: “Phages: Experiments and Modelling.” Dragør, May 2006. “Computational Philosophy.” Niels Bohr Institute, October 2007 “Small Systems Biology.” Dragør, May 2010 “Genome Maintenance and consequence.” Niels Bohr Institute, September 2010 Minischool: “Spatio-temporal patterns in simple bio-systems.” Niels Bohr Institute, August 2011. “DNA dynamics and life strategies.” Krogerup Summerscool, September 2012. “Dynamics of Stem Cells Decision.” Niels Bohr Institute, September 2013. “Models of Life” Krogerup, August 2015.

Major Research Grant: Director of the Center for Models of life, 2005-2015, with total budget of 50MDkk (∼ 7MEuro).