A MAJOR REVISION Coming in March l A New Coauthor l A New Organization l A New Illustration Program

l Many New Topics (see inside) ...... ABOUT THE BOOK

Evolution, Fourth Edition Douglas J. Futuyma and Mark Kirkpatrick l A New Coauthor Extensively rewritten and reorganized, this new edition of fea- l A New Organization tures a new coauthor: Mark Kirkpatrick (The University of Texas at Austin) l A New Illustration Program offers additional expertise in evolutionary genetics and genomics, the fastest-developing area of evolutionary biology. Directed toward an under- graduate audience, the text emphasizes the interplay between theory and empirical tests of hypotheses, thus acquainting students with the process of science. It addresses major themes—including the history of evolution, evolutionary processes, adaptation, and evolution as an explanatory framework—at levels of biological organization ranging from genomes to ecological communities.

March 2017 l 594 pages (est.) l 516 illustrations (est.) ISBN 978-1-60535-605-1 l casebound $137.95 Suggested list price l $110.36 Net price to resellers New in This Edition l Genomic perspectives on evolution are strengthened throughout. l The content has a stronger focus on human evolution: an entirely new chapter on the topic (Chapter 21, The Evolutionary Story of Homo sapiens), and new examples throughout the book. l Many chapters have been rewritten from the ground up. l The book has been entirely reillustrated in a clean, contemporary style that enhances the content. l A new Appendix, A Statistics Primer, introduces the concept of a probability distribution, reviews how statistics are used to describe populations, looks at how we estimate quantities, and discusses how hypotheses are tested. It ends with a brief overview of two major frameworks of statistical analysis: likelihood and Bayesian inference. Math is kept to a minimum.

Print Edition l Order from our website for a 15% discount from suggested list price. ($117.26) STUDENTS l Free standard ground shipping to U.S. addresses. l Orders usually ship in 1–4 business days. SAVE! l Offer not available to resellers. Looseleaf Edition l Discounted 35% from suggested list price of the bound print edition. ($89.67) l Additional 15% discount with free shipping at our website also applies. ($76.22) eBook l Suggested list discounted 50% from bound book list price for a 180-day subscription. ($68.98) l Suggested list discounted 15% from bound book list price to own permanently. ($117.26) l Formats include BryteWave, RedShelf, VitalSource, and YUZU. l All major mobile devices are supported.

Prices subject to change May 1 and November 1, yearly. l Many New Topics (see inside) ...... ABOUT THE THE AUTHORS AUTHORS MEDIA AND SUPPLEMENTS

Douglas J. Futuyma is Distinguished Profes- sor in the Department of Ecology and Evolution For the Student at the State University of New York at Stony Companion Website (evolution4e.sinauer.com) Brook. He received his B.S. from Cornell Univer- The Evolution, Fourth Edition Companion Website features review and study sity and his Ph.D. in Zoology at the University of tools to help students master the key concepts presented in the textbook. Michigan with Lawrence Slobodkin. Dr. Futuyma Access to the site is free of charge, and requires no access code. (Instructor is the author of three previous editions of Evo- registration is required in order for students to access the quizzes.) The site lution, as well as three editions of its predeces- includes the following resources: sor, Evolutionary Biology. He received the 1997 l Chapter Outlines and Summaries: Concise overviews of the important Sewall Wright Award of the American Society of topics covered in each chapter. Naturalists and the 2012 Joseph Leidy Award l Data Analysis Exercises: These inquiry-based exercises involve students of the Academy of Natural Sciences of Drexel in working with data and analyzing methods and conclusions from University (Philadelphia). Dr. Futuyma has served published papers. as President of the Society for the Study of l Simulation Exercises: Interactive modules that allow students to explore Evolution, the American Society of Naturalists, many of the dynamic processes of evolution, and answer questions and the American Institute of Biological Scienc- based on the results they observe. es, and was elected a Fellow of the American l Online Quizzes: Quizzes that cover all the major concepts introduced in Academy of Arts and Sciences in 1996 and the each chapter. These quizzes are assignable by the instructor. National Academy of Sciences in 2006. He has l Flashcards: Easy-to-use flashcard activities that help students learn and served as Editor of Evolution and is currently Ed- review all the key terminology introduced in each chapter. itor of the Annual Review of Ecology, Evolution, l and Systematics. In 2013, he was recognized as The complete Glossary Honorary Doctor by the National University of For the Instructor (available to qualified adopters) Mongolia. An avid naturalist, his major research Instructor’s Resource Library interests include evolution of interactions among insects and plants, , and evolution of The Evolution, Fourth Edition Instructor’s Resource Library includes a variety community structure. of resources to help you develop your course and deliver your lectures. The IRL includes the following: Mark Kirkpatrick is the Painter Centennial l Textbook Figures and Tables: All the figures (including photographs) and Professor of Genetics in the Department of tables from the textbook are provided as JPEGs, reformatted and Integrative Biology at the University of Texas at relabeled for optimal readability when projected. Austin. He received his B.A. in Biology from Har- l PowerPoint Presentations: For each chapter, all of the figures and tables vard in 1978 and his Ph.D. in Zoology from the are provided in a ready-to-use PowerPoint presentation that includes with Monty Slatkin in titles and full captions. 1983. Dr. Kirkpatrick has received a Guggenheim l Answers to the textbook end-of-chapter Problems and Discussion Topics Fellowship (1997) and a Poste Rouge Fellowship l Quiz Questions from the Companion Website (France, 1997). He is a Fellow of the American l Data Analysis and Simulation Exercises from the Companion Website, Academy of Arts and Sciences (2008), and of with answers the American Association for the Advancement of Science (2016). Dr. Kirkpatrick received the Online Quizzing Sewall Wright Award from the American Society A set of online quizzes is available via the Companion Website. These of Naturalists (2014). He has served as Associate quizzes can be assigned or released for student self-study, at the instructor’s Editor of The American Naturalist, Theoretical discretion. Instructors can also add their own questions to the quizzing Population Biology, and Genetics, and on the Ed- system, to create custom quizzes. Results can be viewed online or down- itorial Boards of The Annual Review of Ecology, loaded for use in gradebook programs. (Instructor registration is required Evolution, and Systematics and Proceedings of for student access to the quizzes.) the Royal Society of London B. Dr. Kirkpatrick’s research interests are in evolutionary genetics. He has worked on , quantitative genetics, speciation, and species ranges. Current research topics include the evolution of sex deter- mination and chromosome rearrangements. CHAPTER HIGHLIGHTS Chapters marked by an asterisk* have been entirely rewritten. Elements in blue italics have been extensively revised from the Third Edition.

1. Evolutionary Biology l Molecular signatures of adaptation l How do quantitative traits change by l l evolution of allele frequencies? More succinct history of evolutionary Evolutionary side effects and tradeoffs: l biologynct history of evolutionary pleiotropy and linkage Selection gradients: Interpretation, l Deleterious mutations and the mutation measurement, and values in nature 2. The Tree of Life load in humans l Expanded treatment of artificial selection l Combines previous chapters on l The evolution of mean fitness l Evolutionary rescue phylogeny and patterns of evolution l QTL (quantitative trait locus) mapping l 6. Phenotypic Evolution Elementary method of phylogenetic * l The genetics of quantitative traits, within inference l Less technical approach to quantitative and between species l Not only organisms have phylogenies traits and selection 3. Natural Selection and Adaptation l More streamlined than in previous editions l Adaptive evolution observed l Selfish genes and unselfish behavior l Imperfections and constraints l Natural selection and the evolution of diversity 4. Mutation and Variation* l Smoother integration of Mendelian and l A modern view of recombination that covers both prokaryotes and eukaryotes l Somatic mutation and cancer l Nongenetic inheritance 5. The Genetical Theory of Natural Selection* l A simplified approach to the genetics of natural selection l Examples of recent adaptation in humans CHAPTER HIGHLIGHTS Chapters marked by an asterisk* have been entirely rewritten. Elements in blue italics have been extensively revised from the Third Edition.

7. Genetic Drift: l Detecting selection using genomic data l The evolution of species’ ranges; Evolution at Random* from humans and other species response to climate change l Drift in forward time and backward time 8. Evolution in Space 9. Species and Speciation* (the coalescent) l NEW l Causes and Combines chapters on species and l Estimating effective population sizes consequences of gene flow speciation from earlier editions l Codon bias and selection vs. drift l Gene flow vs. selection l Prezygotic isolation often evolves before l Inbreeding load versus inbreeding l Gene swamping postzygotic isolation l depression l Estimating gene flow from genetic data Speciation by genetic conflict l l Examples of drift in human populations l The evolution of dispersal Speciation by random genetic drift l Parapatric speciation 10. All About Sex* l What are females and males? l The diversity and evolution of sex determination mechanisms l Operational sex ratio and sexual selection l Alternative male mating strategies l Sexual selection on flowering plants l The evolution of recombination by selective interference and other factors 11. How To Be Fit l Evolution of ecological specialists and generalists l Nonadaptive evolution of specialization 12. Conflict and Cooperation* l Green-beard evolution of cooperation l Selfishness can evolve by kin selection l Eusociality can evolve in several ways l A worked example of an ESS l Evolution of spite

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DOUGLAS J. FUTUYMA and MARK KIRKPATRICK l Selfish genes: transposons, segregation 16. Phylogeny: Unity and Diversity l Phylogeny and classification distortion, and cytonuclear conflict l Why estimating phylogenies can be hard l 17. The History of Life Evolution of virulent and avirulent l Parsimony, maximum likelihood, and l parasites Origin of eukaryotes from Archaea Bayesian methods l l Cooperation and major transitions in l Possible causes of the Cambrian Phylogenies based on phenotypes explosion evolution l Discovering the history of genes and l Angiosperm diversification in early 13. Interactions among Species cultures Cretaceous l l Red Queen coevolution Ancestral state reconstruction and 18. The Geography of Evolution l Species diversity in ecological functional studies l l communities The comparative method Explaining disjunct distributions by dispersal 14. The Evolution of Genes and Genomes* l The birth and death of genes l de novo genes l Gene trafficking l Alternative splicing l Evolution of chromosome number l Adaptive and deleterious effects of transposable elements l Evolution of genome size 15. Evolution and Development l Extensively revised, updated, and streamlined l Comparative development and evolution l Signaling molecules and morphological patterns l Evolution of cis- and trans-regulation l Evolution of phenotypic integration l Phenotypic plasticity and adaptation

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To request an examination copy, visit our website: sinauer.com DOUGLAS J. FUTUYMA and MARK KIRKPATRICK 19. The Evolution of l Explaining variable rates of evolution l Agriculture: its pros and cons Biological Diversity l Does speciation accelerate evolution? l Genetic diversity and adaptation in l Diversity-dependent vs. diversity- human populations 21. The Evolutionary l independent rates of diversification NEW Evolutionary mismatches with Story of Homo sapiens modern environments l 20. Macroevolution: Evolution How humans differ from other apes l Natural selection on modern humans l above the Species Level l The physical evolution of hominins Cultural evolution l Development and evolutionary enigmas l The evolution of brain and language l 22. Evolution and Society Biological homology and novel l Our genetic history (including l characters hybridization) Answering evolutionary skeptics l Practical applications: using organisms’ adaptations l Agriculture, pest management, conservation, health and medicine l Evolution and human behavior Appendix: A Statistics Primer NEW l Uses of statistics l Probability distributions l Descriptive statistics: means, variances, regressions, principle components l Estimation l Hypothesis testing: null hypotheses, significance, parametric tests, randomization l Likelihood l Bayesian inference

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A MAJOR REVISION, COMING IN MARCH

Evolution, Fourth Edition Douglas J. Futuyma and Mark Kirkpatrick l A New Coauthor l A New Organization l A New Illustration Program l Many New Topics (see inside)

SAMPLE PAGE From the NEW Appendix