Certification Examination in Neurology
Total Page：16
File Type：pdf, Size：1020Kb
Load more
Recommended publications
-
Group Studies in Experimental Neuropsychology
C HAPTER 3 4 GROUP STUDIES IN EXPERIMENTAL NEUROPSYCHOLOGY Lesley K. Fellows WHY NEUROPSYCHOLOGY? individual differences in skull shape (explicitly thought to be a proxy for underlying brain structure) A fundamental assumption of neuropsychology, and in relation to individual differences in behavior. of cognitive neuroscience more generally, is that Complex traits like benevolence and wit were thus behavior has a biological basis—that it results from related to particular parts of the brain. Although the processes that are executed in the nervous system. methods are clearly flawed to the eye of the modern Following from this assumption, emotions, reader, the underlying concept of localization, that thoughts, percepts, and actions can be understood brain structure and function are related, had a major in neurobiological terms. This premise was impact on the development of clinical neurology and advanced by the philosophers of ancient Greece, of experimental neuropsychology. supported, in part, by observations of patients with The work of Broca, Wernicke, and other 19th- brain injury (Gross, 1995). The fact that damage to and early 20th-century neurologists illustrated how the brain could lead to paralysis, disorders of sensa- observation in clinical populations can (a) provide tion, or even disruptions of consciousness suggested insights into how a complex behavior (like lan- that this organ was the seat of such abilities, guage) can be segmented into simpler components although the broad claim that brain function under- (e.g., production and comprehension) and (b) how lies behavior was not without controversy over the such components can be related to specific regions centuries that followed (Crivellato & Ribatti, 2007). -
NEUROLINGUISTICS Valentina Bambini*
Jan-Ola Östman & Jef Verschueren Handbook of Pragmatics (2012) © 2012 John Benjamins Publishing Company. Not to be reproduced in any form without written permission from the publisher. NEUROLINGUISTICS Valentina Bambini* 1. Definition Neurolinguistics is the study of language-brain relations. Its final goal is the com- prehension and explanation of the neural bases for language knowledge and use. Neurolinguistics is by its nature an interdisciplinary enterprise, and straddles the borders between linguistics and other disciplines that are connected to the study of the mind/brain (mainly cognitive psychology, neuropsychology and cognitive neuroscience). When approached from the point of view of the neurosciences, neurolinguistics focuses on how the brain behaves in language processes, both in healthy and pathological conditions; conversely, from a linguistics standpoint, neu- rolinguistics aims at clarifying how language structures can be instantiated in the brain, i.e. how patterns and rules exhibited in human languages are represented and grounded in the brain. In addition, neurolinguistics has a fundamental clinical impact for assessment and treatment of patients suffering from aphasia and other language pathologies. The field was officially opened up by the nineteenth-century neurologist Paul Broca with his observations of the correlation between language disturbance and brain damage. Since then, over 100 years of investigation into the organization of language in the brain were based on a lesion-deficit approach, in a localizationist perspective. The significance of a brain area was deduced through observation of deficits following a lesion to that brain region, and the exact localization of the lesion was verified through post-mortem examination. The aphasiological era developed a functional model of language production and comprehension that highlighted the 2 Valentina Bambini role of frontal and temporal regions (and connections between them) in the left hemisphere, a model that has informed diagnosis and research up to date. -
Neurobehavioral Anatomy, Third Edition
CONTENTS Preface to the Third Edition xi Chapter One: BEHAVIOR AND THE BRAIN 1 The Mind-Brain Problem 2 General Features of Brain Anatomy 5 The Excesses of Phrenology 13 Behavioral Neurology 14 References 21 Chapter Two: MENTAL STATUS EVALUATION 25 History and Interview 25 Mental Status Examination 28 Standardized Mental Status Testing 40 References 44 vii viii CO N TE N TS Chapter Three: DISORDERS OF AROUSAL AND ATTENTION 49 Arousal Dysfunction 51 Attentional Dysfunction 54 References 60 Chapter Four: MEMORY DISORDERS 63 Inattention 64 Amnesia 65 Remote Memory Loss 71 References 72 Chapter Five: LANGUAGE DISORDERS 75 Cerebral Dominance and Handedness 78 Aphasia 80 Alexia 86 Agraphia 89 References 90 Chapter Six: APRAXIA 95 Limb Kinetic Apraxia 97 Ideomotor Apraxia 97 Ideational Apraxia 101 References 102 Chapter Seven: AGNOSIA 105 Visual Agnosia 107 Auditory Agnosia 112 Tactile Agnosia 113 References 114 Chapter Eight: RIGHT HEMISPHERE SYNDROMES 119 Constructional Apraxia 120 Neglect 121 Spatial Disorientation 124 Dressing Apraxia 124 Aprosody 125 CO N TE N TS ix Amusia 127 Emotional Disorders 129 References 134 Chapter Nine: TEMPORAL LOBE SYNDROMES 139 The Limbic System 140 Temporal Lobe Epilepsy 143 Psychosis in Temporal Lobe Epilepsy 147 Temporal Lobe Epilepsy Personality 150 References 155 Chapter Ten: FRONTAL LOBE SYNDROMES 159 Orbitofrontal Syndrome 163 Dorsolateral Syndrome 166 Medial Frontal Syndrome 167 Functions of the Frontal Lobes 168 References 172 Chapter Eleven: TRAUMATIC BRAIN INJURY 175 Focal Lesions 176 Diffuse Lesions 178 References 185 Chapter Twelve: DEMENTIA 189 Cortical Dementias 194 Subcortical Dementias 200 White Matter Dementias 205 Mixed Dementias 214 References 218 Epilogue 227 Glossary of Neurobehavioral Terms 229 Index 241 C H AP T E R O N E BEHAVIOR AND THE BRAIN Human behavior has an enduring appeal. -
Fmri Brain-Computer Interface: a Tool for Neuroscientific Research And
Hindawi Publishing Corporation Computational Intelligence and Neuroscience Volume 2007, Article ID 25487, 10 pages doi:10.1155/2007/25487 Review Article fMRI Brain-Computer Interface: A Tool for Neuroscientific Research and Treatment Ranganatha Sitaram,1 Andrea Caria,1 Ralf Veit,1, 2 Tilman Gaber,1, 2 Giuseppina Rota,1, 3 Andrea Kuebler,1 and Niels Birbaumer1, 4 1 Institute of Medical Psychology and Behavioral Neurobiology, Eberhard-Karls-University of Tubingen,¨ 72074 Tubingen,¨ Germany 2 Max Planck Institute for Biological Cybernetics, P.O. Box 21 69, 72076 Tubingen,¨ Germany 3 Institute for Natural Language Processing, University of Stuttgart, 70174 Stuttgart, Germany 4 National Institute of Health (NIH), NINDS, Human Cortical Physiology, Bethesda, MD 20892-1428, USA Correspondence should be addressed to Ranganatha Sitaram, [email protected] Received 28 February 2007; Revised 2 August 2007; Accepted 18 September 2007 Recommended by Shangkai Gao Brain-computer interfaces based on functional magnetic resonance imaging (fMRI-BCI) allow volitional control of anatomically specific regions of the brain. Technological advancement in higher field MRI scanners, fast data acquisition sequences, prepro- cessing algorithms, and robust statistical analysis are anticipated to make fMRI-BCI more widely available and applicable. This noninvasive technique could potentially complement the traditional neuroscientific experimental methods by varying the activity of the neural substrates of a region of interest as an independent variable to study its effects on behavior. If the neurobiological basis of a disorder (e.g., chronic pain, motor diseases, psychopathy, social phobia, depression) is known in terms of abnormal activity in certain regions of the brain, fMRI-BCI can be targeted to modify activity in those regions with high specificity for treatment. -
Priming and the Brain Review
Neuron, Vol. 20, 185±195, February, 1998, Copyright 1998 by Cell Press Priming and the Brain Review Daniel L. Schacter*§ and Randy L. Buckner²³ minutes to several hours, subjects are given three-letter *Department of Psychology word stems with multiple possible completions and are Harvard University asked to complete each stem with the first word that Cambridge, Massachusetts 02138 comes to mind (e.g., mot___ for the target word ªmotelº). ² Department of Psychology Priming occurs when subjects complete the stem with Washington University a designated target completion more often for words St. Louis, Missouri 63130 that had been studied earlier than for words that were ³ MGH-NMR Center not studied previously. In a related kind of experiment, Charlestown, Massachusetts 02129 subjects study a list of words and are later given a word identification test, where words are flashed briefly (e.g., Introduction for 35 ms) and subjects attempt to identify them. Priming occurs when subjects identify more previously studied Research in cognitive psychology, neuropsychology, words than nonstudied words. Similar kinds of tasks and neuroscience has converged recently on the idea have been developed for examining priming of numer- that memory is composed of dissociable forms and sys- ous different types of stimuli, including pseudowords tems (Squire, 1992; Roediger and McDermott, 1993; (Keane et al., 1995; Bowers, 1996), familiar and unfa- Schacter and Tulving, 1994; Willingham, 1997). This con- miliar objects (Biederman and Cooper, 1991; Srinivas, clusion has been based on experimental and theoretical 1993; Schacter et al., 1993b), visual patterns (Musen analyses of a variety of different phenomena of learning and Squire, 1992), and environmental sounds (Chiu and and memory. -
Behavioral Neurology Fellowship Core Curriculum
AMERICAN ACADEMY OF NEUROLOGY BEHAVIORAL NEUROLOGY FELLOWSHIP CORE CURRICULUM 1. INTRODUCTION AND DEFINITIONS The specialty of Behavioral Neurology focuses on clinical and pathological aspects of neural processes associated with mental activity, subsuming cognitive functions, emotional states, and social behavior. Historically, the principal emphasis of Behavioral Neurology has been to characterize the phenomenology and pathophysiology of intellectual disturbances in relation to brain dysfunction, clinical diagnosis, and treatment. Representative cognitive domains of interest include attention, memory, language, high-order perceptual processing, skilled motor activities, and "frontal" or "executive" cognitive functions (adaptive problem-solving operations, abstract conceptualization, insight, planning, and sequencing, among others). Advances in cognitive neuroscience afforded by functional brain imaging techniques, electrophysiological methods, and experimental cognitive neuropsychology have nurtured the ongoing evolution and growth of Behavioral Neurology as a neurological subspecialty. Applying advances in basic neuroscience research, Behavioral Neurology is expanding our understanding of the neurobiological bases of cognition, emotions and social behavior. Although Behavioral Neurology and neuropsychiatry share some common areas of interest, the two fields differ in their scope and fundamental approaches, which reflect larger differences between neurology and psychiatry. Behavioral Neurology encompasses three general types of clinical -
The Brain and Behavior
This page intentionally left blank The Brain and Behavior The Brain and Behavior An Introduction to Behavioral Neuroanatomy Third Edition David L. Clark Nash N. Boutros Mario F. Mendez CAMBRIDGE UNIVERSITY PRESS Cambridge, New York, Melbourne, Madrid, Cape Town, Singapore, São Paulo, Delhi, Dubai, Tokyo Cambridge University Press The Edinburgh Building, Cambridge CB2 8RU, UK Published in the United States of America by Cambridge University Press, New York www.cambridge.org Information on this title: www.cambridge.org/9780521142298 © D. Clark, N. Boutros, M. Mendez 2010 This publication is in copyright. Subject to statutory exception and to the provision of relevant collective licensing agreements, no reproduction of any part may take place without the written permission of Cambridge University Press. First published in print format 2010 ISBN-13 978-0-511-77469-0 eBook (EBL) ISBN-13 978-0-521-14229-8 Paperback Cambridge University Press has no responsibility for the persistence or accuracy of urls for external or third-party internet websites referred to in this publication, and does not guarantee that any content on such websites is, or will remain, accurate or appropriate. Every effort has been made in preparing this book to provide accurate and up-to- date information which is in accord with accepted standards and practice at the time of publication. Although case histories are drawn from actual cases, every effort has been made to disguise the identities of the individuals involved. Nevertheless, the authors, editors, and publishers can make no warranties that the information contained herein is totally free from error, not least because clinical standards are constantly changing through research and regulation. -
Functional Imaging in Behavioral Neurology and Cognitive Neuropsychology
Functional Imaging in Behavioral Neurology and Cognitive Neuropsychology Geoffrey Karl Aguirre From: T. E. Feinberg & M. J. Farah (Eds.), Behavioral Neurology and Cognitive Neuropsychology . (in press). New York: McGraw Hill. Introduction What can we hope to learn of the physical operation of the central nervous system and the mental processes that result? The fields of behavioral neurology and cognitive neuropsychology survey this relationship, and have at their disposal powerful intellectual and methodological tools. While the terrain of possible models of brain and behavior interaction seems boundless, particular tests of these models may exist beyond the reach of particular methods. These methods fall into two broad categories, and have been around for several centuries. The first category includes manipulations of the neural substrate itself. Such an intervention might inactivate a brain area, perhaps through a lesion, with Paul Broca’s 1861 observation of the link between language and left frontal lobe damage providing a prototypical example. The effects of stimulation of brain areas can also be studied, as Harvey Cushing did with the human sensory cortex in the early 20th century. In contrast, observation techniques relate a measure of neural function to behavior. Hans Berger’s work in the 1920s on the human electroencephalographic response is a good starting point. Impressive refinements and additions to both of these categories have taken place over the last century. For example, beyond the static lesions of “nature’s accidents” that have been the mainstay of cognitive neuropsychology for many years, it is now possible to temporarily and reversibly inactivate areas of human cortex using transcranial magnetic stimulation (see chapter X for additional details). -
Introduction to Neurolinguistics
Introduction to Neurolinguistics Aniela Improta França UFRJ (Federal University of Rio de Janeiro, Brazil) This is an account of Introduction to Neurolinguistics, a week-long course that took place during the First South American Summer School in Formal Linguistics (EVELIN ’04), UNICAMP, São Paulo, Brazil. Classes ranged from an overview of brain anatomy and an introduction to neurolinguistics protocols to the comparative analysis of neurolinguistics and medical research about the Language Faculty. 1. About the course Neurolinguistics is a branch of Cognitive Neuroscience, that, on its turn, together with many other fields such as Systemic, Movement, Sensory, Cellular and others, is a branch of a larger domain named the Neurosciences. Neurolinguistics can still be divided into two areas: language acquisition and processing and language impairment. THE NEUROSCIENCES Cognitive Systemic Movement Sensory Cellular Neurolinguistics Vision Hearing Attention Memory Language Acquisition Language Impairment Language Processing The focus on language impairment is a historic one, dating from 400 b.C., with Hippocrates’ accounts on infirmities that produced lack of language. Contrastingly, the questions about the healthy Faculty of Language – how we come to acquire and use our mother tongue – have been systematically taken for granted through a long stretch of history, despite the fact that language is the one cognition that definitely sets us apart from other animals on this planet. In reality, language investigation has only taken a definite bio-linguistic course in the 1950’s with the advent of Noam Chomsky’s Generative Grammar (Chomsky, 1957, 1965). And the neurophysiological characterization of the healthy Faculty of Language, that is, the understanding of language-brain relations at work, only started being investigated specially in the late 1980’s, with the introduction of non-invasive cognitive assessment techniques that brought new and exciting perspectives into the field. -
Review Article Finding the Intersection of Neuroplasticity, Stroke Recovery, and Learning: Scope and Contributions to Stroke Rehabilitation
Hindawi Neural Plasticity Volume 2019, Article ID 5232374, 15 pages https://doi.org/10.1155/2019/5232374 Review Article Finding the Intersection of Neuroplasticity, Stroke Recovery, and Learning: Scope and Contributions to Stroke Rehabilitation Leeanne Carey ,1,2 Alistair Walsh ,1,2 Achini Adikari ,3 Peter Goodin,2,4 Damminda Alahakoon,3 Daswin De Silva,3 Kok-Leong Ong,;3 Michael Nilsson ,1,5,6 and Lara Boyd 7 1Occupational Therapy, School of Allied Health, Human Sciences and Sport, College of Science, Health and Engineering, La Trobe University, Bundoora, VIC 3086, Australia 2Neurorehabilitation and Recovery, Stroke Division, Florey Institute of Neuroscience and Mental Health, Heidelberg VIC 3084, Australia 3Research Centre for Data Analytics and Cognition, La Trobe University, Bundoora, VIC 3086, Australia 4Department of Medicine and Neurology, Melbourne Brain Centre, Royal Melbourne Hospital, Parkville, VIC 3050, Australia 5Faculty of Health and Medicine and Centre for Rehab Innovations, The University of Newcastle, Callaghan NSW 2308, Australia 6LKC School of Medicine, Nanyang Technological University (NTU), 308232, Singapore 7Djavad Mowafaghian Centre for Brain Health, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada V6T 1Z3 Correspondence should be addressed to Leeanne Carey; [email protected], Michael Nilsson; [email protected], and Lara Boyd; [email protected] Received 24 November 2018; Revised 4 February 2019; Accepted 24 March 2019; Published 2 May 2019 Academic Editor: Yasuo Terao Copyright © 2019 Leeanne Carey et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. -
Memory Dysfunction INTRODUCTION Distributed Brain Networks
Memory Dysfunction REVIEW ARTICLE 07/09/2018 on SruuCyaLiGD/095xRqJ2PzgDYuM98ZB494KP9rwScvIkQrYai2aioRZDTyulujJ/fqPksscQKqke3QAnIva1ZqwEKekuwNqyUWcnSLnClNQLfnPrUdnEcDXOJLeG3sr/HuiNevTSNcdMFp1i4FoTX9EXYGXm/fCfl4vTgtAk5QA/xTymSTD9kwHmmkNHlYfO by https://journals.lww.com/continuum from Downloaded By G. Peter Gliebus, MD Downloaded CONTINUUM AUDIO INTERVIEW AVAILABLE ONLINE from https://journals.lww.com/continuum ABSTRACT PURPOSE OF REVIEW: This article reviews the current understanding of memory system anatomy and physiology, as well as relevant evaluation methods and pathologic processes. by SruuCyaLiGD/095xRqJ2PzgDYuM98ZB494KP9rwScvIkQrYai2aioRZDTyulujJ/fqPksscQKqke3QAnIva1ZqwEKekuwNqyUWcnSLnClNQLfnPrUdnEcDXOJLeG3sr/HuiNevTSNcdMFp1i4FoTX9EXYGXm/fCfl4vTgtAk5QA/xTymSTD9kwHmmkNHlYfO RECENT FINDINGS: Our understanding of memory formation advances each year. Successful episodic memory formation depends not only on intact medial temporal lobe structures but also on well-orchestrated interactions with other large-scale brain networks that support executive and semantic processing functions. Recent discoveries of cognitive control networks have helped in understanding the interaction between memory systems and executive systems. These interactions allow access to past experiences and enable comparisons between past experiences and external and internal information. The semantic memory system is less clearly defined anatomically. Anterior, lateral, and inferior temporal lobe regions appear to play a crucial role in the function of the semantic -
Neuropsychiatry and Neuroscience Milestones for General Psychiatry Trainees
Acad Psychiatry DOI 10.1007/s40596-014-0112-0 SPECIAL ELEMENT: TASK FORCE REPORT Neuropsychiatry and Neuroscience Milestones for General Psychiatry Trainees Sheldon Benjamin & Alik Widge & Kailie Shaw Received: 16 December 2013 /Accepted: 13 March 2014 # Academic Psychiatry 2014 For nearly 50 years, psychiatric thought leaders have sug- purported to offer additional neurological data, it is also gested that advances in our understanding of the brain should important for trainees to be able to discriminate among lead psychiatry training to include more clinical neuroscience evidence-based and nonevidence-based modalities. [1–13]. The importance to psychiatric training of a foundation 2. As healthcare reform causes care systems to focus on in neurology has been acknowledged since at least 1939, disorders that are most complex and costly to the system, when the predecessor of the Accreditation Council on Grad- the house of medicine looks to psychiatry to recognize uate Medical Education (ACGME), the American Medical and treat psychiatric comorbidities that tend to increase Association (AMA) Council on Medical Education and Hos- the cost of care [15–18]. Similarly, psychiatrists must pitals, established the requirement that “a program of graduate utilize neurodiagnostic resources carefully in an area of studies should run concurrently with clinical instruction, cov- accountable, value-oriented care. Diagnostic precision ering the fundamentals of neuroanatomy, neuropathology, and tailored treatment ultimately lead to more efficient neurophysiology, psychobiology, and psychopathology medicine. Recognition of neurologic comorbidities of [14].” In 1987, the ACGME and American Board of Psychi- psychiatric disorders leads to earlier treatment for these atry and Neurology (ABPN) initiated the current two-month disorders and better quality of life.