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Zika Virus Outside Africa Edward B
Zika Virus Outside Africa Edward B. Hayes Zika virus (ZIKV) is a flavivirus related to yellow fever, est (4). Serologic studies indicated that humans could also dengue, West Nile, and Japanese encephalitis viruses. In be infected (5). Transmission of ZIKV by artificially fed 2007 ZIKV caused an outbreak of relatively mild disease Ae. aegypti mosquitoes to mice and a monkey in a labora- characterized by rash, arthralgia, and conjunctivitis on Yap tory was reported in 1956 (6). Island in the southwestern Pacific Ocean. This was the first ZIKV was isolated from humans in Nigeria during time that ZIKV was detected outside of Africa and Asia. The studies conducted in 1968 and during 1971–1975; in 1 history, transmission dynamics, virology, and clinical mani- festations of ZIKV disease are discussed, along with the study, 40% of the persons tested had neutralizing antibody possibility for diagnostic confusion between ZIKV illness to ZIKV (7–9). Human isolates were obtained from febrile and dengue. The emergence of ZIKV outside of its previ- children 10 months, 2 years (2 cases), and 3 years of age, ously known geographic range should prompt awareness of all without other clinical details described, and from a 10 the potential for ZIKV to spread to other Pacific islands and year-old boy with fever, headache, and body pains (7,8). the Americas. From 1951 through 1981, serologic evidence of human ZIKV infection was reported from other African coun- tries such as Uganda, Tanzania, Egypt, Central African n April 2007, an outbreak of illness characterized by rash, Republic, Sierra Leone (10), and Gabon, and in parts of arthralgia, and conjunctivitis was reported on Yap Island I Asia including India, Malaysia, the Philippines, Thailand, in the Federated States of Micronesia. -
Data-Driven Identification of Potential Zika Virus Vectors Michelle V Evans1,2*, Tad a Dallas1,3, Barbara a Han4, Courtney C Murdock1,2,5,6,7,8, John M Drake1,2,8
RESEARCH ARTICLE Data-driven identification of potential Zika virus vectors Michelle V Evans1,2*, Tad A Dallas1,3, Barbara A Han4, Courtney C Murdock1,2,5,6,7,8, John M Drake1,2,8 1Odum School of Ecology, University of Georgia, Athens, United States; 2Center for the Ecology of Infectious Diseases, University of Georgia, Athens, United States; 3Department of Environmental Science and Policy, University of California-Davis, Davis, United States; 4Cary Institute of Ecosystem Studies, Millbrook, United States; 5Department of Infectious Disease, University of Georgia, Athens, United States; 6Center for Tropical Emerging Global Diseases, University of Georgia, Athens, United States; 7Center for Vaccines and Immunology, University of Georgia, Athens, United States; 8River Basin Center, University of Georgia, Athens, United States Abstract Zika is an emerging virus whose rapid spread is of great public health concern. Knowledge about transmission remains incomplete, especially concerning potential transmission in geographic areas in which it has not yet been introduced. To identify unknown vectors of Zika, we developed a data-driven model linking vector species and the Zika virus via vector-virus trait combinations that confer a propensity toward associations in an ecological network connecting flaviviruses and their mosquito vectors. Our model predicts that thirty-five species may be able to transmit the virus, seven of which are found in the continental United States, including Culex quinquefasciatus and Cx. pipiens. We suggest that empirical studies prioritize these species to confirm predictions of vector competence, enabling the correct identification of populations at risk for transmission within the United States. *For correspondence: mvevans@ DOI: 10.7554/eLife.22053.001 uga.edu Competing interests: The authors declare that no competing interests exist. -
Chikungunya Virus, Epidemiology, Clinics and Phylogenesis: a Review
Asian Pacific Journal of Tropical Medicine (2014)925-932 925 Contents lists available at ScienceDirect IF: 0.926 Asian Pacific Journal of Tropical Medicine journal homepage:www.elsevier.com/locate/apjtm Document heading doi:10.1016/S1995-7645(14)60164-4 Chikungunya virus, epidemiology, clinics and phylogenesis: A review Alessandra Lo Presti1, Alessia Lai2, Eleonora Cella1, Gianguglielmo Zehender2, Massimo Ciccozzi1,3* 1Department of Infectious Parasitic and Immunomediated Diseases, Epidemiology Unit, Reference Centre on Phylogeny, Molecular Epidemiology and Microbial Evolution (FEMEM), Istituto Superiore di Sanita`, Rome, Italy 2Department of Biomedical and Clinical Sciences, L. Sacco Hospital, University of Milan, Milan, Italy 3University Campus-Biomedico, Rome, Italy ARTICLE INFO ABSTRACT Article history: Chikungunya virus is a mosquito-transmitted alphavirus that causes chikungunya fever, a febrile Received 14 April 2014 illness associated with severe arthralgia and rash. Chikungunya virus is transmitted by culicine Received in revised form 15 July 2014 mosquitoes; Chikungunya virus replicates in the skin, disseminates to liver, muscle, joints, Accepted 15 October 2014 lymphoid tissue and brain, presumably through the blood. Phylogenetic studies showed that the Available online 20 December 2014 Indian Ocean and the Indian subcontinent epidemics were caused by two different introductions of distinct strains of East/Central/South African genotype of CHIKV. The paraphyletic grouping Keywords: of African CHIK viruses supports the historical -
William Hepburn Russell Lumsden Scotland Has a Proud History of Nurturing Distinguished Contributors to Our Understanding of Disease in the Tropics
William Hepburn Russell Lumsden Scotland has a proud history of nurturing distinguished contributors to our understanding of disease in the tropics. Among these must be numbered Russell Lumsden, medical entomologist, virologist and parasitologist, but above all a man with boundless enthusiasm for the entire natural world. Russell became a keen naturalist while still at school. Born in Forfar on 27 March, 1914, he moved with his family to Darlington in 1919 when his father became Schools’ Medical Officer for Durham County. He was educated at the Queen Elizabeth Grammar School there, but in 1931 he was awarded a Carnegie Scholarship to read Zoology at Glasgow University under Sir John Graham Kerr. Russell took part in successive student expeditions to Canna in the Inner Hebrides and wrote detailed reports on the entomology of these and on various projects in marine biology. His dedication to natural history is splendidly illustrated by a paper in The Entomologist’s Monthly Magazine, recounting how, while sunning himself on a jetty at Lake Windermere after swimming, he found an old nail and kept a tally of the different prey of pond skaters by making scratches on the woodwork. After graduation with First Class Honours, Russell went on to qualify in medicine at Glasgow and wrote articles for Surgo, the Glasgow University Medical Journal, acting as its editor in 1938. His companion in all his student activities was Alexander J Haddow, (later FRSE, FRS): both were later to become world authorities on mosquito- borne disease. After receiving his medical degree in 1938, Russell was awarded a Medical Research Council Fellowship for work at the Liverpool School of Tropical Medicine. -
ED351246.Pdf
DOCUMENT RESUME ED 351 246 SO 022 469 TITLE National Endowment for the Humanities, Twenty-Sixth Annual Report, 1991. INSTITUTION National Endowment for the Humanities (NFAH), Washington, D.C. REPORT NO ISSN-8755-5492 PUB DATE 92 NOTE 202p.; For the 24th Annual Report, see ED 322 064. PUB TYPE Reports Descriptive (141) EDRS PRICE MF01/PC09 Plus Postage. DESCRIPTORS Elementary Secondary Education; *Federal Aid; *Federal Programs; *Grants; Higher Education; *Humanities; Research IDENTIFIERS *National Endowment for the Humanities ABSTRACT This report contains brief descriptions of National Endowment for the Humanities programs as well as a complete listing of all Endowment grants, entered by the division and program in which they were funded, for fiscal year 1991 (October 1,1990 through September 30, 1991). The contents of the report are as follows; "Twenty Years of the Jefferson Lecture"; "Letter from the Deputy Chairman"; "How the Endowment Works"; "National Tests"; "The Charles Frankel Prize, Division of Education Programs"; "Division of Fellowships and Seminars"; "Division of Public Programs"; "Division of Research Programs"; "Division of State Programs"; "Office of Challenge Grants, Office of Preservation"; "Panelists in Fiscal Year 1991"; "Senior Staff Members of the Endowment"; "Members of the National Council on the Humanities"; "Summary of Grants and Awards for Fiscal Year 1991"; "Financial Report for Fiscal Year 1991"; and "Index of Grants." (DB) *********************************************************************** Reproductions -
Final Report of the Rockefeller Foundation Bellagio Center Convening: October 21–23, 2015
FINAL REPORT OF THE ROCKEFELLER FOUNDATION BELLAGIO CENTER CONVENING: OCTOBer 21–23, 2015 SUPPORTED BY FRONT COVER, FRONTISPIECE, PAGE 17, AND BACK COVER. Survivors in Guinea, Liberia, and Sierra Leone continue to face stigma, trauma, and long-term effects of the virus (AP Photo). II EFFECTIVE PUBLIC HEALTH COMMUNICATION IN AN INTERCONNECTED WORLD CONTENTS 2 Introduction – Setting the Scene: 30 Expert Insights: Key Areas Public Health Communication in an of Need and Opportunity Interconnected World 31 i. Barriers to Building Trust 4 Objectives of this Project in Public Health Communications 6 About KYNE and Ebola Deeply 36 ii. Collecting and Scaling Best Practices 7 Acknowledgments 38 iii. Managing Social Media 10 The High Stakes for Mass Public Engagement of Communication Failures 41 iv. Improving the Impact of Mainstream Media Coverage 12 How Communication Can Help or Hinder a Response 44 Developing Tools and Technology 13 i. Case Study – Ebola in West Africa: 45 i. Advanced Technology Platforms BBC Media Action 47 ii. Internet Forums and Websites 18 ii. Case Study – Managing SARS in Singapore 48 iii. Research and Knowledge Management Systems 25 iii. Case Study – Legionnaires’ Disease in New York City: The New York 50 Communications City Office of Emergency and Public Health Governance Preparedness and Response 51 i. Effective Leadership Communication 52 ii. The Role of National and Regional Governments 54 iii. Inclusive Communication at the Community Level 56 Shaping Effective Community Engagement 57 i. Conscious Community Engagement 58 ii. Communicating with Communities (CwC) 60 iii. Enhanced Partnerships with Local Media 64 Conclusion and Recommendations 67 Key Recommendations INTRODUCTION Search and rescue operations underway in Port-au-Prince on January 15, 2010 (Photo by IFRC/Eric Quintero via Flickr). -
Democracy & Philanthropy
DEMOCRACY & PHILANTHROPY The Rockefeller Foundation and the American Experiment the rockefeller foundation centennial series democracy & philanthropy the rockefeller foundation and the american experiment By Eric John Abrahamson Sam Hurst Barbara Shubinski Innovation for the Next 100 Years Rockefeller Foundation Centennial Series 2 Chapter _: Democracy & Philanthropy 3 4 Chapter _: Democracy & Philanthropy 5 6 Chapter _: Democracy & Philanthropy 7 8 Chapter _: Democracy & Philanthropy 9 Preface from Dr. Judith Rodin 14 Foreword – Justice Sandra Day O'Connor 18 1 The Charter Fight 24 11 Government by Experts 52 111 Philanthropy at War 90 © 2013 by Rockefeller Foundation have been deemed to be owned by 1v The Arts, the Humanities, The Rockefeller Foundation Centennial Series the Rockefeller Foundation unless we and National Identity 112 Foreword copyright Justice Sandra Books published in the Rockefeller were able to determine otherwise. Day O’Connor Foundation Centennial Series provide Specific permission has been granted All rights reserved. case studies for people around the by the copyright holder to use the v Foundations Under Fire 144 world who are working “to promote the following works: well-being of humankind.” Three books Top: Rockefeller Archive Center Equal Opportunity for All 174 Bottom: John Foxx. Getty Images. highlight lessons learned in the fields Ruthie Abel: 8-9, 110-111 v1 of agriculture, health, and philanthropy. Art Resource: 26 Three others explore the Foundation’s Book design by Pentagram. The Johns Hopkins Bloomberg School of v11 Democracy and Design work in Africa, Thailand, and the United Public Health: 57 States. For more information about Democracy & Philanthropy: Department of Special Collections in America's Cities 210 the Rockefeller Foundation Centennial and University Archives, Marquette The Rockefeller Foundation and initiatives, visit http://centennial. -
John D. Rockefeller (1839-1937) Topic Guide for Chronicling America (
John D. Rockefeller (1839-1937) Topic Guide for Chronicling America (http://chroniclingamerica.loc.gov) Introduction John D. Rockefeller was an oil industry tycoon and philanthropist who lived in Cleveland, Ohio. Born in New York in 1839, he moved with his family to northeast Ohio in 1853. At age sixteen, he began his involvement with the business world as an assistant bookkeeper for a produce commission business. He soon began his own produce commission company before joining the oil refinery industry in 1863. He established Standard Oil of Ohio in 1870, and this is where he made most of his wealth. By 1878, the company controlled 90% of all U.S. oil refineries (it was declared a trust by the U.S government in 1911). In addition to his business interests, Rockefeller regularly donated a portion of his income to charities supporting education and public health. Rockefeller died in 1937 and is buried in Lake View Cemetery in Cleveland. He is widely recognized as the wealthiest American of all time. Important Dates . July 8, 1839: John Davison Rockefeller is born in Richford, New York. 1853: The Rockefeller family moves to Strongsville, a suburb of Cleveland, Ohio. 1863: Rockefeller and business partner Maurice B. Clark build an oil refinery in “The Flats” area of Cleveland. 1864: Rockefeller marries Laura Celestia “Cettie” Spelman. January 10, 1870: Standard Oil of Ohio is formed and grows rapidly over the next decade, eventually forming a monopoly. 1903: Rockefeller’s General Education Board is founded. 1911: U.S. Supreme Court declares that Standard Oil Company of New Jersey is a trust, and it is broken into subsidiaries. -
K-12 NATIONAL TESTING ACTION PROGRAM (NTAP) Connecting Schools with the Nation’S Leading Testing Companies to Safely Reopen TABLE of CONTENTS
K-12 NATIONAL TESTING ACTION PROGRAM (NTAP) Connecting schools with the nation’s leading testing companies to safely reopen TABLE OF CONTENTS Introduction and current K-12 landscape 7 Successful programs: testing works to keep schools safer 12 K-12 National Testing Action Program: overview 24 K-12 National Testing Action Program: logistics 39 Appendix and references 53 2 CONTEXT The K-12 National Testing Action Program (NTAP) is a plan to provide free Covid-19 testing for K-12 public schools to enable safe in-person learning Situation Complication Question Answer • Due to Covid-19, a • Teachers, students and • How do we safely and 1. Implementation of full majority of US K-12 communities may fear the spread sustainably re-open the safety and mitigation public schools are of Covid-19 in schools nation’s K-12 public activities operating remotely or in • Schools are not fully equipped to schools as quickly as hybrid learning 2. Prioritized vaccination provide necessary mitigation possible? for teachers and staff • Online learning is not an measures including testing • How do we make testing 3. Weekly testing for adequate replacement • While testing capacity exists, labs free, easy and widely for in-person school and students, teachers and do not have a clear signal on how available for schools? staff is creating large to make capacity readily education and available to schools socialization gaps • The value of testing is getting lost amid the focus on vaccination 3 K-12 NATIONAL TESTING ACTION PROGRAM (NTAP) SUMMARY (1 OF 2) The school changes -
Natural Infection of Aedes Aegypti, Ae. Albopictus and Culex Spp. with Zika Virus in Medellin, Colombia Infección Natural De Aedes Aegypti, Ae
Investigación original Natural infection of Aedes aegypti, Ae. albopictus and Culex spp. with Zika virus in Medellin, Colombia Infección natural de Aedes aegypti, Ae. albopictus y Culex spp. con virus Zika en Medellín, Colombia Juliana Pérez-Pérez1 CvLAC, Raúl Alberto Rojo-Ospina2, Enrique Henao3, Paola García-Huertas4 CvLAC, Omar Triana-Chavez5 CvLAC, Guillermo Rúa-Uribe6 CvLAC Abstract Fecha correspondencia: Introduction: The Zika virus has generated serious epidemics in the different Recibido: marzo 28 de 2018. countries where it has been reported and Colombia has not been the exception. Revisado: junio 28 de 2019. Although in these epidemics Aedes aegypti traditionally has been the primary Aceptado: julio 5 de 2019. vector, other species could also be involved in the transmission. Methods: Mosquitoes were captured with entomological aspirators on a monthly ba- Forma de citar: sis between March and September of 2017, in four houses around each of Pérez-Pérez J, Rojo-Ospina the 250 entomological surveillance traps installed by the Secretaria de Sa- RA, Henao E, García-Huertas lud de Medellin (Colombia). Additionally, 70 Educational Institutions and 30 P, Triana-Chavez O, Rúa-Uribe Health Centers were visited each month. Results: 2 504 mosquitoes were G. Natural infection of Aedes captured and grouped into 1045 pools to be analyzed by RT-PCR for the aegypti, Ae. albopictus and Culex detection of Zika virus. Twenty-six pools of Aedes aegypti, two pools of Ae. spp. with Zika virus in Medellin, albopictus and one for Culex quinquefasciatus were positive for Zika virus. Colombia. Rev CES Med 2019. Conclusion: The presence of this virus in the three species and the abundance 33(3): 175-181. -
Children's Mental Health in the United States
Children’s Mental Health in the United States: The Development of Child Psychiatry at Johns Hopkins, 1890-1945 by Alysia Young Han A dissertation submitted in partial satisfaction of the Requirements for the degree of Doctor of Philosophy in History in the Graduate Division of the University of California, Berkeley Committee in charge: Professor Thomas Laqueur, Chair Professor James Vernon Professor Charis Thompson Fall 2012 Children’s Mental Health in the United States: The Development of Child Psychiatry at Johns Hopkins, 1890-1945 © 2012 by Alysia Young Han TABLE OF CONTENTS CHAPTER 1 1 Introduction CHAPTER 2 9 Adolf Meyer and the Social Potential of Children, 1913-1925 CHAPTER 3 26 Training Social Workers at Johns Hopkins, 1919-1929 CHAPTER 4 51 Treating the “Whole Child”: Pediatrics, Psychiatry, and Philanthropy CHAPTER 5 68 Leo Kanner’s Clinic, 1931-1945: Developing a Specialty EPILOGUE 86 BIBLIOGRAPHY 88 Acknowledgements I am indebted to my committee members - Tom Laqueur, James Vernon, and Charis Thompson - for their persistence, encouragement, and faith throughout the last decade. I also wish to thank Marc Jacobs, Stuart Lustig, and Victor Reus at UCSF who worked with me to create possibilities to pursue research and writing during residency and fellowship. Special thanks goes to Penny Ismay and my sister Clara Han for their critical engagement with my work. Finally, enough cannot be said for my friends and family who were my life support throughout this strenuous process. Thank you. ii ABSTRACT Children’s Mental Health in the United States: The Development of Child Psychiatry at Johns Hopkins, 1890-1945 by Alysia Young Han Doctor of Philosophy in History University of California, Berkeley Professor Thomas Laqueur, Chair This dissertation tracks the development of child psychiatry as a medical specialty as it emerged at Johns Hopkins University from 1890 to 1945. -
Possible Non-Sylvatic Transmission of Yellow Fever Between Non-Human Primates in São Paulo City, Brazil, 2017–2018
www.nature.com/scientificreports OPEN Possible non‑sylvatic transmission of yellow fever between non‑human primates in São Paulo city, Brazil, 2017–2018 Mariana Sequetin Cunha1*, Rosa Maria Tubaki2, Regiane Maria Tironi de Menezes2, Mariza Pereira3, Giovana Santos Caleiro1,4, Esmenia Coelho3, Leila del Castillo Saad5, Natalia Coelho Couto de Azevedo Fernandes6, Juliana Mariotti Guerra6, Juliana Silva Nogueira1, Juliana Laurito Summa7, Amanda Aparecida Cardoso Coimbra7, Ticiana Zwarg7, Steven S. Witkin4,8, Luís Filipe Mucci3, Maria do Carmo Sampaio Tavares Timenetsky9, Ester Cerdeira Sabino4 & Juliana Telles de Deus3 Yellow Fever (YF) is a severe disease caused by Yellow Fever Virus (YFV), endemic in some parts of Africa and America. In Brazil, YFV is maintained by a sylvatic transmission cycle involving non‑human primates (NHP) and forest canopy‑dwelling mosquitoes, mainly Haemagogus‑spp and Sabethes-spp. Beginning in 2016, Brazil faced one of the largest Yellow Fever (YF) outbreaks in recent decades, mainly in the southeastern region. In São Paulo city, YFV was detected in October 2017 in Aloutta monkeys in an Atlantic Forest area. From 542 NHP, a total of 162 NHP were YFV positive by RT-qPCR and/or immunohistochemistry, being 22 Callithrix-spp. most from urban areas. Entomological collections executed did not detect the presence of strictly sylvatic mosquitoes. Three mosquito pools were positive for YFV, 2 Haemagogus leucocelaenus, and 1 Aedes scapularis. In summary, YFV in the São Paulo urban area was detected mainly in resident marmosets, and synanthropic mosquitoes were likely involved in viral transmission. Yellow Fever virus (YFV) is an arbovirus member of the Flavivirus genus, family Flaviviridae and the causative agent of yellow fever (YF)1.