F Day 1 – September 22, 2021 Pre-conference Symposium – Live, Virtual Only 9:00 AM - 3:30 PM CDT

A01: A Grant Writing Retreat to Jump Start or Advance Your Proposal 5.0 Contact Hours Speakers: Sarah Kalia, ScM, CGC, Harvard University; Beverly Yashar, MS, PhD, CGC, ; Julia Wynn, MS, MS, CGC, Columbia University; Erin Linnenbringer, PhD, MS, CGC, Washington University; John Quillin, PhD, MPH, CGC, Virginia Commonwealth University; Courtney Berrios, MSc, ScM, CGC, Children's Mercy Research Institute Moderator: Courtney Berrios, MSc, ScM, CGC, Children's Mercy Research Institute  Identify essential content to include in key sections of a grant proposal.  Evaluate grant proposal ideas based on discussions with a genetic counselor experienced with grant writing and/or review and other genetic counselors who are developing grant proposals.  Draft and/or revise specific aims and research plan drafts for a genetic counselor-led grant proposal.  Develop and submit a complete genetic counselor-led grant proposal within the next year with the mentorship of a genetic counselor experienced with grant writing and/or review.

Pre-conference Symposia – in New Orleans 9:00 AM - 3:30 PM CDT

A02: Collecting Metrics to Improve Quality and Outcomes: Approaches, Resources and Taking the First Steps 5.0 Contact Hours Speakers: Karen Wain, MS, CGC, Geisinger; David Blaisdell, BA, Discern Health; Caiqian Cropper, MS, CGC, Concert Genetics; Debi Cragun, PhD, MC, CGC, University of South Florida; Erin Miller, MS, LGC, Cincinnati Children’s Hospital; Jessica Goehringer, MS, LCGC, Geisinger; Cary Armstrong; Lauren Ryan, MS, LCGC, GRAIL, Inc.; Zachary Salvati, MS, CGC, Geisinger; Stephanie Cohen, MS, LCGC, Ascension St. Vincent; Tanya Eble, MS, Baylor College of Medicine Moderator: Alanna Kulchak Rahm, PhD, MS, CGC  Describe what is meant by quality metrics.  Describe the difference between quality improvement, quality assurance and research.  Identify three reasons to collect metrics.  Demonstrate how genetic counselors are poised to lead efforts in quality efforts. Held in New Orleans

A03: Create the Change: Grassroots J.E.D.I. Initiatives 5.0 Contact Hours Speakers: Melanie Hardy, MS, MS, CGC, Jscreen; Maia Borensztein, MS, CGC, Stanford Children's Health; Joanna Mercado, MS, CGC, Genome Medical Services; Nivi Ahlawat, BS, AllStripes; Carla McGruder, MS, CGC, Color Health; Amanda Bergner, MS, CGC, Columbia University Moderator: MaryAnn Campion, EdD, MS, CGC  Describe diverse J.E.D.I. initiatives underway at a variety of organizations, including graduate programs, clinical teams, research programs, trainee forums, and lab/industry groups.  Enact strategies to engage multiple stakeholders and garner buy-in within one’s community.  Define acceptable outcome measures to ensure sustainable change.  Determine how to evaluate progress in and barriers to specific initiatives. Held in New Orleans

A04: Enhancing the Therapeutic Relationship to Improve Patient Outcomes 5.0 Contact Hours Speakers: Kendra L Schaa, ScM, University of Iowa Hospitals & Clinics; Mike Setzer, ScM, NIH - National Institute of Allergy and Infectious Diseases; Morgan Similuk, ScM, NIH - National Institute of Allergy and Infectious Diseases; Barbara Biesecker, MS, PhD, RTI International; Amy Turriff, ScM, NIH - National Human Genome Research Institute Moderator: Kendra L Schaa, ScM, University of Iowa Hospitals & Clinics  Delineate evidence-based patient outcomes associated with a counseling model of practice.  List the common factors of a therapeutic relationship.  Recognize importance of common factors across diverse populations and clinical settings.  Evaluate use of common factors as they contribute to the therapeutic relationship. Held in New Orleans

A05: Somatic Genetic Therapies: Clinical Uses and Genetic Counselors’ Roles 5.0 Contact Hours Speakers: Katherine Donohue, MS, MA, CGC, The Icahn School of Medicine at Mount Sinai; Cassandra Barrett, PhD, LGC, UVA Medical Center; Nirav Shah; Monica Bhatia; Petra Kaufmann; Jacqueline Karp, MD, FDA; Amber Freed, MAcc, SLC6A1 Connect; Ariel Lager, Metrus Energy; Hetanshi Naik, PhD, MS, CGC, Icahn School of Medicine at Mount Sinai; Anna DeSalvo, MS, CGC, National Marrow Donor Program/ Be The Match; Ryan Miller, MS, CGC, PTC Therapeutics; Meg Bradbury; Tammy Boyd Moderator: Katherine Donohue, MS, MA, CGC, The Icahn School of Medicine at Mount Sinai  Summarize the basics of wide variety of genetic therapy techniques for somatic gene therapy including gene augmentation such as gene editing and gene addition, and gene inhibition.  Discuss the benefits and limitations of different genetic therapeutic methods.  Identify the current uses of genetic therapies in clinical practice and outcomes of recent groundbreaking trials in CAR T-cell therapies including background on mechanism, sickle cell therapies, and neurological disease therapies.  Recognize future applications of how gene therapy may impact patient care. Held in New Orleans

Pre-conference Symposia, Online, On-demand A06: Oncofertility Genetic Counseling: Ensuring Comprehensive Reproductive Options for Individuals with Hereditary Cancer Syndromes 5.0 Contact Hours Speakers: Kristen Miller, MGC, CGC; Kamaria Cayton-Vaught, MD; Jennifer Levine, MD; Jordan Brown, MA, MS, LCGC; Aishwarya Arjunan, MS, MPH, CGC, CPH; Karen Hurley, PhD Moderator: Kristen Miller, MGC, CGC; Jordan Brown, MA, MS, LCGC  Define oncofertility, its emergence as a distinct discipline relevant to the genetic counselor, and how it can be used to maximize reproductive outcomes for individuals with HC.  Review current challenges faced by reproductive and oncology genetic counselors alike when caring for patients with hereditary cancer syndromes.  Identify barriers to accessing FP and IVF/PGT-M for adults and children with hereditary cancer syndromes across diverse US populations.  Discuss strategies for increasing accessibility of HC testing in the obstetrical setting and the role of the genetic counselor in oncofertility for pediatric and young adult cancer patients of all genders.

Opening Plenary Session 4:15 PM - 5:00 PM CDT

A07: Empathy in Action: A Personal Journey of Treacher Collins Syndrome 0.75 Contact Hour Speaker: Sam Drazin, B.A. in Education, Founder and Executive Director, Changing Perspectives  Examine the lived experience of an individual with Treacher Collins who is also a diversity/inclusion/equity educator.  Identify aspects of J.E.D.I. that need improving in the medical community, particularly for patients with rare genetic disorders.  Summarize the speaker’s sentiments regarding genetic counseling and testing (for both diagnostic and reproductive health) in the context of his diagnosis.  List 2-3 specific actions genetic counselors can take as healthcare providers to improve social- emotional sensitivity, equity and inclusion for all patients, regardless of clinical indication. *This session will be live-broadcasted from New Orleans to virtual attendees Day 2 – September 23, 2021 Sponsored Symposium 8:15 AM - 8:45 AM CDT

Myriad Sponsored Symposium  Learning objectives to be announced. Sponsored by: Myriad Held in New Orleans

What is SMART About Screening for 22q11.2?  Patient impact and clinical actionability of 22q11.2 deletion screening.  Review the SMART Study. Describe the improvements in SNP-based NIPT for common chromosome abnormalities and microdeletions.Sponsored by: Natera Held in New Orleans

Plenary Session 9:00 AM - 9:45 AM CDT

B03: The Devil is in the Details: Race-Based Medicine and Healthcare Disparities in Genetic Counseling 0.75 Contact Hour Speakers: Elizabeth Fieg, MS, CGC, Brigham and Women's Hospital; Sally Rodriguez, ScM, CGC, Sequence46; Carla McGruder, MS, LCGC Color Genomics  Examine how race is used inappropriately to guide clinical decisions regarding the ordering and interpretation of genetic tests in three specialty areas of genetics - prenatal carrier screening, polygenic risk scores in cancer, and pharmacogenomics.  Discuss how race differs from ancestry and ethnicity, the importance of using correct terminology in a clinical or research context, and how these demographics can be ethically utilized in genetic counseling practice.  Describe opportunities for genetic counselors to play an active role in combating race-based medicine and expanding equal access to genetic services across minority patient population groups. *This session will be live-broadcasted from New Orleans to virtual attendees

Educational Breakout Sessions 10:30 AM - 12:00 PM CDT

B04: Debates in Cardiology: Are Inherited Heart Diseases Monogenic? 1.5 Contact Hours Speakers: Robyn Hylind, MS, CGC, Boston Children's Hospital; Mellisa Kelly, MS, LGC, Geisinger; Elizabeth Jordan, MMSc, LCGC, The Ohio State University; Cynthia James, ScM, PhD, CGC, Johns Hopkins University Moderator: Matthew Thomas, ScM, CGC, University of Virginia  Describe the emerging data on population frequency of pathogenic cardiac variants.  Discern the implications of modifiers in penetrance of inherited heart disease.  Challenge historic data on natural history and penetrance of genetic conditions.

Held in New Orleans

B05: Gender-Inclusive Genetic Counseling: What Have We Learned and How Do We Incorporate It into Our Practice? 1.5 Contact Hours Speakers: Nadia Dowshen, MD, MSHP, Children's Hospital of Philadelphia; Andy Cantor, MS, LCGC, Integrated Genetics; Hallie Lyninger, MS, LCGC, Norton Healthcare; Danielle McKenna, MS, CGC, University of Pennsylvania Abramson Cancer Center Moderator: Diane Koeller, MS, MPH, CGC, Dana-Farber Cancer Institute  Describe the gender affirmation process from psychological, social, and medical perspectives.  Summarize recent literature and research surrounding genetic counseling for TGNB populations.  Integrate gender inclusivity into genetic counseling practice. *This session will be live-broadcasted from New Orleans to virtual attendees

B06: Health Equity in Prenatal Screening: A Potential Roadmap and Patient Views 1.5 Contact Hours Speakers: Natasha Bonhomme, BA, Genetic Alliance; Irene Aninye, PhD, Society for Women's Health Research; Altovise Ewing, PhD, Genentech; Marianna Raia; Patricia Winters, MS, CGC, Illumina, Inc Moderator: Kathryn Schubert, MPP, Society for Women's Health Research  Identify the barriers to accessing non-invasive prenatal screening (NIPS) and expanded carrier screening (ECS) for patients.  Understand patient views surrounding access to NIPS.  Discuss strategies that address health equity with respect to the barriers to access and disparities in access to non-invasive prenatal screening and expanded carrier screening. Held in New Orleans

B07: It’s Messy: Navigating Ethical Issues in Clinical Research 1.5 Contact Hours Speakers: Katherine Donohue, MS, MA, CGC, The Icahn School of Medicine at Mount Sinai; Laynie Dratch, ScM, CGC, University of Pennsylvania; Aaron Baldwin, MS, LCGC, University of Pennsylvania; Pamela Brock, MS, CGC, Ohio State University; Carla McGruder, MS, LCGC, Color Health Moderator: Emily Higgs, MS, FHGSA, Stanford University; Katherine Donohue, MS, MA, CGC, The Icahn School of Medicine at Mount Sinai  Identify key ethical issues common in clinical research.  Summarize three ethical frameworks that can be utilized in these scenarios, such as Utilitarianism, Virtue Ethics, and Casuistry.  Examine how multiple ethical frameworks could be applied to the same problem.  Apply various frameworks to ethical challenges in clinical research. Held in New Orleans

B08: To Test or Not to Test Children for Adult-onset Hereditary Cancer Genes? T’is the Question 1.5 Contact Hours Leila Jamal, ScM, PhD, CGC, National Cancer Institute, NIH; Sarah Scollon, MS, CGC, Baylor College of Medicine/Texas Children's Hospital; Kami Wolfe Schneider, MS, CGC, University of Colorado Anschutz Medical Campus; Rose McGee, MS, CGC, St. Jude Children's Research Hospital; Natalie Waligorski, MS, MPH, CGC, Seattle Children's Hospital; Shannon Stasi, MS, CGC, Seattle Children's Hospital; Emily Bonkowski, ScM, CGC, Seattle Children's Hospital, University of Washington; Kristin Zelley, MS, LCGC, Children's Hospital of Philadelphia  Examine the ethical frameworks that inform decisions about whether to test minors for adult- onset cancer syndromes.  Apply ethical principles in a debate format to cases that involve testing for adult-onset cancer genes in minors.  Evaluate ethical concepts such as autonomy through a culturally-competent lens.  Illustrate the lived experience of patients and family members considering or requesting testing for adult-onset cancer syndromes. Held in New Orleans

Sponsored Symposium 12:45 PM - 1:30 PM CDT

BRCA Mutation and Homologous Recombination Deficiency (HRD) Testing in Advanced Ovarian and Metastatic Breast Cancer  Examine the molecular biology of the homologous recombination repair (HRR) pathway and how homologous recombination deficiency (HRD) relates to carcinogenesis  Explore the role of PARP inhibition in cancers with HRD  Discuss clinical considerations for molecular testing in advanced ovarian and metastatic breast cancer Review guideline recommendations for identifying HRD-positive advanced ovarian cancer and BRCA mutation-positive metastatic breast cancerSponsored by: AstraZeneca Held in New Orleans

Better Together: The Importance of Both Germline Genetic Testing and Somatic Tumor Profiling  Review the clinical utility of germline genetic testing and somatic tumor profiling as part of the comprehensive workup of the oncology patient. Examine various clinical implementation approaches, including paired and reflex, for germline and somatic testing.Sponsored by: Invitae Held in New Orleans

Lecture Concurrent with Workshops 1:45 PM - 3:45 PM CDT

B11: From Altruism to Obligation: How Research Participation is not as Voluntary as We Envisioned 2.0 Contact Hours Speakers: Carla McGruder, MS, LCGC, Color Genomics; Deanna Darnes, CGC, Fetal Care Center Dallas; Nathan Pearson, PhD Moderator: Carla McGruder, MS, LCGC, Color Genomics  Examine examples of how involuntary research participation is framed in clinical settings and how lack of transparency erodes trust in Black communities.  Analyze current consent forms from surgical procedures, clinical trials and genetic screenings to identify ethical dilemmas.  Work through ways to reword, reframe, and reform the consenting process with the involvement of patients and other health providers.  Discuss how limited access to treatment and care may hinder future participant interest in all research. *This session will be live-broadcasted from New Orleans to virtual attendees Workshops 1:45 PM - 3:45 PM CDT

B12: "Yes, And": Broadening Genetic Counseling Skills Through Applied Improv 2.0 Contact Hours Speakers: Elizabeth Fieg, MS, CGC, Brigham and Women's Hospital; Helen Kim, MA, MS, LGC, Hunt Cancer Institute at Torrance Memorial Medical Center; MaryAnn Campion, EdD, MS, CGC, Stanford University Moderator: Elizabeth Fieg, MS, CGC, Brigham and Women's Hospital  Utilize improvisation exercises to build skills in effectively and spontaneously reacting to unknown and unpredictable situations and communicating with empathy and clarity.  Develop tools through applied improv to manage and accept uncertainty and ambiguity in any situation.  Incorporate applied improv and mindfulness techniques to encourage participants to take risks and step out of their comfort zone.  Provide challenges and learning opportunities through exercises grounded in principles of spontaneity, adaptability, collaboration, and skilled listening. Held in New Orleans B13: Checking Our Blind Spots: A Discussion of Bias and Miscommunication in the Genetic Counseling Session 2.0 Contact Hours Speaker: Rebekah Hutchins, MS, GC, Northside Hospital Moderator: Nikkola Carmichael, PhD, MS, CGC, Boston Children's Hospital/Brandeis University  Explain how implicit and explicit bias impact our lives and practice, and the different levels at which we are aware of bias.  Apply strategies for observing, analyzing, and comparing different aspects of culture, specifically in the context of a genetic counseling session.  Employ strategies for counseling diverse patients in the clinic.  Enhance the effectiveness of counseling sessions by navigating and accommodating cultural differences. Held in New Orleans

B14: Building a Framework for Holistic Review 2.0 Contact Hours Holly Zimmerman, MS, CGC, University of Nebraska Medical Center; Annie Wildermuth, MMS, PA-C, RD, University of Nebraska Medical Center, Division of PA Education; Angela Trepanier, MS, CGC, ; Brad Rolf, MS, CGC, University of Washington; Jen Eichmeyer, MS, CGC, Boise State University; Andrea Hanson-Kahn, MS, CGC, Stanford University Medical Center; Maggie Winnicki, MPH, University of Nebraska Medical Center  Define holistic admissions.  Discuss various frameworks for holistic review of applicants including mission-based and competency-based admissions.  Summarize the experiences of incorporating holistic admissions for an established program.  Examine how several genetic counseling programs approach holistic admissions. Held in New Orleans

B15: Non-Violent Communication: Leading and Participating in Constructive Dialogue about J.E.D.I. 2.0 Contact Hours Speakers: Ana Morales, MS, CGC, Invitae; Altovise Ewing, PhD, LCGC, Genentech; Vicki Sapp, PhD, Geisinger Commonwealth School of Medicine; Sarah Walker, PhD, Creighton University Moderator: Ana Morales, MS, CGC, Invitae  Define micro- and macro-aggressions generally and in the context of the GC community.  Discuss the framework of Marshall Rosenberg’s .  Compare bystander to upstander behaviors when witnessing a microaggression.  Practice promoting a safe, constructive dialogue using Nonviolent Communication.  Integrate allyship when responding to a colleague who calls someone out for a microaggression.  Create an inclusive, safe, and brave culture for conversations around microaggressions. Held in New Orleans

B16: Forward Momentum: Variant Classification Primer and Collaboration with Genetic Testing Laboratories 2.0 Contact Hours Speakers: Tara Hart, MS, CGC, GeneDx; Elizabeth Heise; Melissa Kelly; Karen Wain, MS, CGC, Geisinger, Autism & Developmental Medicine Institute; Matthew Thomas, ScM, CGC, University of Virginia  Illustrate how to use the American College of Medical Genetics and Genomics Standards and Guidelines for the Interpretation of Sequence Variants.  Review how to critically assess medical and scientific literature to aid in variant interpretation.  Demonstrate the role of ClinVar working groups in variant interpretation.  Discuss the value of sharing proband and family history information with a lab to aid in variant interpretation.  Recognize the role of a genetic counselor in clinic in assessing genetic testing reports.

Held in New Orleans

Plenary Session 4:45 PM - 5:30 PM CDT

B17: The Latin American Immigrant Experience in Genetic Counseling: Our Clients, Colleagues & the Communities We Serve 0.75 Contact Hour Speakers: Charité Ricker, MS, CGC, University of Southern California; Daniela Diaz Caro, BS, Stanford University Moderator: Erica Ramos, MS, CGC, Genome Medical  Discuss and compare the challenges faced by Hispanic/Latinx immigrants from Mexico, Central and South America, and the Caribbean to non-immigrants in the United States healthcare system.  Identify opportunities to integrate recommendations and guidance on caring for immigrant populations into clinical care, genetic testing workflows, and research initiatives.  Identify approaches to better understand the experiences of and support students and colleagues who are immigrants. *This session will be live-broadcasted from New Orleans to virtual attendees

Day 3 – September 24, 2021 Sponsored Symposium 8:15 AM - 8:45 AM CDT

Ambry Sponsored Symposium  Learning objectives to be announced. Sponsored by: Ambry Genetics Held in New Orleans

Prenatal Testing: When Multiple Technologies Reveal More than Meets the Eye  Case study demonstrating how genome-wide NIPT can guide diagnostic testing  Clinical scenario illustrating different laboratories work together to provide comprehensive care, testing and answers to patients and providers Clinical case where single gene sequencing, with VUS reporting, detected carrier status not previously reported. Sponsored by Labcorp Held in New Orleans

Plenary Sessions 9:00 AM - 9:30 AM CDT

C03: 2021 Janus Lecture - “You Can Never Feel My Pain”: The History and the Future of Sickle Cell Disease 0.5 Contact Hour Barbara Harrison, MS, CGC, Howard University College of Medicine  Review the natural history of sickle cell disease (SCD) and rare complications associated with sickle cell trait.  Identify current treatments and potential cures, including gene therapy, for those with sickle cell disease.  Describe the historical significance of how SCD has been characterized, both medically and in a social context, and how it has contributed to the present experiences of people with SCD.  Discuss the past and current health disparities which impact families affected with the condition, both socially and in clinical care. *This session will be live-broadcasted from New Orleans to virtual attendees

9:30 AM - 10:00 AM CDT

C04: FORWARD Abstracts 0.5 Contact Hour  Describe the barriers underrepresented minorities experience in becoming a competitive genetic counseling program applicant  Examine genetic counseling supervisors’ experiences with remote clinical supervision *This session will be live-broadcasted from New Orleans to virtual attendees

Educational Breakout Sessions 10:30 AM - 12:00 PM CDT

C05: Cultivating Inclusive Supervision Strategies for an Evolving Profession 1.5 Contact Hours Speakers: Krista Redlinger-Grosse, PhD, ScM, LP, LGC, University of Minnesota; Nikkola Carmichael, PhD, MS, CGC, Boston Children’s Hospital/Brandeis University; Annie K. Bao, MS, LMFT, Northwestern University; Ambreen Khan, MS, CGC, Huntsman Cancer Institute Moderator: Shreshtha M. Garg, MS, CGC, Northwestern University  Define the tenets of the reciprocal-engagement model of supervision (REM-S) as it relates to genetic counseling student supervision.  Explore the ways in which the intersection of the identities and experiences of the supervisor, student, and patient contribute to a supervised genetic counseling session.  Deconstruct historical standards of professionalism and interpersonal relationships, and who they serve to benefit.  Integrate strategies for relationship building and providing feedback in a supervisory role based on individual performance. Held in New Orleans

C06: Advancing Liquid Biopsy in Early Detection, Management and Monitoring of Cancer 1.5 Contact Hours Brian Allen, MS, Grail; Krysten Shipley, MS, CGC, Guardant Health; Shifra Krinshpun, MS, CGC, Natera  Discuss emerging applications of liquid biopsy for early detection.  Identify benefits of liquid biopsy for treatment decisions and monitoring minimal residual disease.  Explore the role of the genetic counselor in assessing liquid biopsies for cancer risk assessment, detection and management. Held in New Orleans

C07: Time for reinforcements? A Discussion on Outsourcing Genetic Counseling Services 1.5 Contact Hours Speakers: Kiley Johnson, MS, LCGC, GeneMatters; Jennifer Saucier, MS, CGC, Natera Modeartor: Gillian Hooker, PhD, ScM, CGC, Concert Genetics  Review current disparities in access to genetic counseling services and barriers to accessing services.  Describe telehealth approaches to expanding access to care through partnerships with healthcare systems.  Identify approaches to promote efficiency in telehealth practice to expand an individual genetic counselor’s capacity.  Evaluate the advantages and disadvantages for genetic counselors working for health care systems that contract with outsourced genetic counseling services  Identify strategies for genetic counselors working in healthcare systems to partner with genetic counselors working for outsourced genetic counseling companies and for laboratories.  Evaluate the effectiveness of models of genetic counselor practice and collaboration for increasing genetic counselor service capacity and efficiency. *This session will be live-broadcasted from New Orleans to virtual attendees

C08: Stretching Resources: What to do When Your Clinic is Hyper-inundated with Hypermobility 1.5 Contact Hours Speakers: Lauren Boucher, MS, Mayo Clinic; Elizabeth Fieg, MS, CGC, Brigham and Women's Hospital; Jodie Johnson, MS, CGC, Cincinnati Children's Hospital Medical Center; Lauren Puryear, MS, CGC, University of Washington Medical Center; Natalie Beck, MGC, CGC Genome Medical; Gretchen MacCarrick, MS, CGC, Johns Hopkins School of Medicine Moderator: Gretchen MacCarrick, MS, CGC, Johns Hopkins School of Medicine  Evaluate the role of genetic counselors in health counseling for patients with hypermobility Ehlers Danlos syndrome.  Compare different triage and clinical care models for patients referred for hypermobility.  Understand institutional motivations for development of triage models for patients with hypermobility.  Explore the motivations, goals, and experience of hypermobility EDS patients and how this contributes to their perception within the medical field. Held in New Orleans

Sponsored Symposium 12:45 PM - 1:30 PM CDT

When Bigger Isn’t Always “VOUSier”  Define and explore the use of phenotype-driven analysis for sequencing based tests like WES and WGS.  Compare differences in analysis and reporting when implementing phenotype-driven reporting vs. standard reporting. Summarize several clinical cases demonstrating the utilization of phenotype-driven analysis, and how it can drive benefits in clinic. Sponsored by: PerkinElmer Held in New Orleans

PreventionGenetics Sponsored Symposium  • Following this presentation, attendees will be able to compare test modalities for neurodevelopmental disorders, with a focus on comparisons of strengths and weaknesses between traditional microarray technologies to CNV calls made on exome platforms  • Following this presentation, attendees will be able to employ practice changes to improve care delivery to special needs patient populations • Following this presentation, attendees will be able to identify practice changes to improve personalized treatment options for patient with neurodevelopmental disorders based on genetic testing. Sponsored by: PreventionGenetics Held in New Orleans

Plenary 1:45 PM - 2:45 PM CDT

C11: NSGC State of the Society Address 1.0 Contact Hour Sara Riordan, MS, CGC, NSGC President  Describe the activities of NSGC over the past year as related to the advancement of the profession of genetic counseling.  Assess NSGC’s advocacy efforts over the course of 2021.  Identify opportunities for supporting justice, equity, diversity and inclusion in the profession of genetic counseling. *This session will be live-broadcasted from New Orleans to virtual attendees

2:45 PM - 3:15 PM CDT

Incoming Presidential Address Heather Zierhut, PhD, MS, CGC, NSGC President-elect  Welcome NSGC President-elect Heather Zierhut, as he introduces herself to NSGC members and outlines her vision for NSGC and the genetic counseling profession in 2022.

*This session will be live-broadcasted from New Orleans to virtual attendees

4:15 PM - 5:15 PM CDT

C12: NSGC Professional Issues Panel 1.0 Contact Hour  Learning objectives to be announced. *This session will be live-broadcasted from New Orleans to virtual attendees

Day 4 – September 25, 2021 Sponsored Symposium 8:15 AM - 8:45 AM CDT

Diagnose. Understand. Treat. Delivering Rapid and Reliable Diagnostics To Accelerate Targeted Medical Solutions Demonstrate a multi-pronged approach to accelerating targeted medical solutions.Sponsored by: Centogene Held in New Orleans

The Routine Incorporation of Molecular Ancestry into Carrier Screening: Sema4’s Clinical Experience  Explain molecular ancestry determination and how it provides more accurate, personalized residual risk calculations for carrier screeing results for use in clinical practice. Provide early insights into the experience of a laboratory, healthcare providers and patients with the integration of molecular ancestry into routine carrier screening. Sponsored by: Sema4 Held in New Orleans

Plenary Session 9:00 AM - 10:00 AM CDT

D03: Beverly Rollnick Lecture: The Problem with Race Based Medicine 1.0 Contact Hour Dorothy Roberts, J.D., University of Pennsylvania  Review the history of biological concepts of race in medicine.  Discuss how race-based medicine is related to structural racism and implicit bias.  Describe how health care professionals can combat racism in medicine. *This session will be live-broadcasted from New Orleans to virtual attendees

Sponsored Symposium 12:45 PM - 1:30 PM CDT

Agent of Equity: Carrier Screen with Reflex Single-gene NIPT for Fetal Risk Assessment  Explain how cfDNA technologies can assess fetal risk for recessively inherited conditions. Examine the clinical utility of sgNIPT through case examples. Sponsored by: BillionToOne, Inc. (Unityscreen) Held in New Orleans

Genetics of Neurodegenerative Neuromuscular Disease  Learning objectives to be announced.

Sponsored by: Biogen Held in New Orleans

Plenary Sessions 1:45 PM - 2:15 PM CDT

D11: Audrey Heimler Special Projects Award Presentation 0.5 Contact Hour  Learning objectives to be announced.

*This session will be live-broadcasted from New Orleans to virtual attendees

2:15 PM - 3:00 PM CDT

D12: “Directiveness” in Modern Genetic Counseling: Navigating Our Shared Future with Values, Evidence, and Versatility 0.75 Contact Hour Leila Jamal, ScM, PhD, CGC, National Cancer Institute, NIH  Illustrate how a broad range of ethical principles are relevant to genetic counseling as both our work and workforce grows more diverse.  Using examples, argue that directiveness in genetic counseling is not only acceptable but in some cases desirable.

*This session will be live-broadcasted from New Orleans to virtual attendees

3:30 PM - 4:00 PM CDT

D13: Jane Engelberg Memorial Fellowship Award Presentation 0.5 Contact Hour  Learning objectives to be announced.

*This session will be live-broadcasted from New Orleans to virtual attendees

4:00 PM - 4:45 PM CDT

D14: Plenary Session 0.75 Contact Hour  Session and learning objectives to be announced.

*This session will be live-broadcasted from New Orleans to virtual attendees Day 5 – September 26, 2021 Sponsored Symposium 8:15 AM - 8:45 AM CDT

Myriad Sponsored Symposia  Learning objectives to be announced. Sponsored by: Myriad Held in New Orleans

Scratching the Surface: Exploring the Importance of Genetic Testing in Cerebral Palsy  Examine the significance of genetic testing in Cerebral Palsy (CP) for patients and their families  Share real world experiences in implementing genetic testing for CP patients at a large institution Describe results of the PTC Pinpoint™ program for CP genetic testing Sponsored by: PTC Therapeutics Held in New Orleans

Educational Breakout Sessions 9:00 AM - 10:30 AM CDT E03: Giving Out Raw Data to Patients or Consumers: is It a Good Thing or a Raw Deal? Legal, Ethical and Practical Considerations for Genetic Counselors, Researchers and Genetic Testing Companies 1.5 Contact Hours Speakers: Laura Hercher, MA, MS, CGC, Sarah Lawrence College Joan H. Marks Graduate Program in Human Genetics; Brianne Kirkpatrick, MS, LCGC, Watershed DNA; Christi Guerrini, JD, MPH, Baylor College of Medicine  Identify the potential risks and benefits posed by giving patients, customers and research participants access to the raw data generated by multiple forms of genetic testing.  Identify potential public and private options that could provide regulation and oversight for the release and use of raw data from genetic testing.  Assess the role that genetic counselors can play in guiding patients on the use of raw data and best practices in genetic counseling for patients presenting with results based on third-party analysis of raw data. Held in New Orleans

E04: Leave No Histone Unturned: Recognizing the Phenotypic, Testing and Therapeutic Gems of Epigenetic Conditions 1.5 Contact Hours Speakers: Jill Fahrner, MD, PhD, Johns Hopkins University, Department of Genetic Medicine; Jessica Duis, MD, Children’s Hospital Colorado; Jacquelyn Britton, MGC, CGC, Johns Hopkins University, Department of Genetic Medicine Moderator: Carolyn Applegate, MGC, CGC, Johns Hopkins Medicine  Define Mendelian Disorders of the Epigenetic Machinery (MDEMs).  Name three common phenotypic presentations of epigenetic conditions.  Recognize clinical scenarios for which genome wide methylation analysis may be clinically useful.  Describe two therapeutic approaches to epigenetic conditions. Held in New Orleans E05: Practicing What We Preach: Acceptance and Advocacy for Genetic Counselors with Disabilities and Chronic Conditions 1.5 Contact Hours Speakers: Rachel Mador-House, CGC, Ironwood Cancer and Research Centers; Lauren Propst, MS, CGC, BillionToOne; Chelsea Menke, BS, MS, LCGC, Norton Healthcare; Lauren Sferrazza, MS, LGC, Myriad Genetics Inc.; Ronit Mazzoni, MS, CGC, Santa Clara Valley Medical Center; Laura Fuerstman, MS, CGC; Samantha Stover, MS, CGC, Baylor College of Medicine/Texas Children's Hospital; Allayna Frank, BS, University of Pennsylvania; R. Lynn Holt, MS, University at Alabama at Birmingham Moderator: Lauren Sferrazza, MS, LGC, Myriad Genetics Inc.  Define disability and related terms and describe the prevalence and types of disabilities and chronic conditions within the genetic counseling workforce.  Summarize examples of discrimination based on disabilities and/or chronic conditions within the genetic counseling field.  Examine ways in which the field of genetic counseling can be more inclusive toward, advocate for, and benefit from those genetic counselors and genetic counseling students who identify as having a disability or chronic condition.  Review the legal rights that individuals with disabilities and chronic conditions have regarding disclosure and reasonable accommodations in the workplace and educational settings. *This session will be live-broadcasted from New Orleans to virtual attendees

Plenary Sessions 10:30 AM - 11:00 AM CDT

E06: Outcomes of a Randomized Trial Studying the Accessible, Relational, Inclusive and Actionable (ARIA) Genetic Counseling Approach 0.5 Contact Hour Speaker: Laura Amendola, MS CGC, University of Washington, Division of Medical Genetics  Describe CHARM and the ARIA model, the rationale for and development of the intervention, and the genetic counselor training process.  Review outcomes of the pragmatic, randomized controlled trial comparing ARIA to standard care for the return of exome sequencing results.  Discuss how these findings can inform genetic counseling practice and future care delivery. *This session will be live-broadcasted from New Orleans to virtual attendees

11:00 AM - 11:15 AM CDT

E07: Beth Fine Kaplan Best Student Abstract Award 0.5 Contact Hour  Winner and talk to be announced. *This session will be live-broadcasted from New Orleans to virtual attendees

11:15 AM - 11:30 AM CDT

E08: Best Full Member Abstract Award 0.5 Contact Hour

 Winner and talk to be announced. *This session will be live-broadcasted from New Orleans to virtual attendees

Post-conference Symposia 1:00 PM - 4:30 PM

E09: Follow the Money: Downstream Revenue and Genetic Counseling 3.0 Contact Hours Speakers: Colleen Caleshu, ScM, LCGC, GeneMatters; Caitlin Mauer, MA, MS, CGC, University of Texas Southwestern Medical Center; Colleen Campbell, PhD, MS, LGC, University of Iowa; Athena Puski, MS, CGC, University of Iowa Hospitals & Clinics; Kendra Schaa, ScM, LGC, University of Iowa Hospitals & Clinics; John Sweetenham, MD, FRCP, FACP, FASCO, UT Southwestern Simmons Cancer Center; Matthew Thomas, ScM, CGC, University of Virginia Moderator: Sara Pirzadeh-Miller, MS, CGC, UT Southwestern Medical Center  Recognize use of DSR data for different purposes depending on stakeholders.  Describe a general framework for how to compile DSR data within one’s institution.  Evaluate and apply data compiled on downstream revenue across institutional settings.  Identify resources to initiate or expand DSR assessment in any setting where genetic counselors practice. Held in New Orleans

E10: Soy Consejera/o Genetica/o 3.0 Contact Hours Speakers: Charité Ricker, University of Southern California; Daisy Hernandez, MS, CGC, LAC + USC Medical Center; Priscila Delgado Hodges, LCGC, Indiana University; Susy Malca, MS, LCGC, Providence St. Joseph Health; Jennifer Eichmeyer, MS, CGC, Boise State University; Valentina Caceres, MS, CGC, Nationwide Children's Hospital; Sharisse Jimenez, MA, MS, CGC, Rocky Mountain Cancer Centers Moderator: Charité Ricker, University of Southern California  Review and summarize the status of our current understand about Spanish language genetic counseling.  Discuss established linguistic resources and counseling approaches utilized clinically.  Conduct small group role-playing of clinical scenarios in Spanish among workshop attendees and provide self and group evaluations of activities.  Create strategies for future genetic counseling interactions in Spanish and discuss ways to disseminate these strategies. Held in New Orleans

E11: The Genetics Influencer Workshop: Tackling Misinformation and Finding our Professional Voice on the Next Generation of Social Media 3.0 Contact Hours Speakers: Dena Goldberg, MS, CGC, Dena DNA; Sarah Mitra Mojarad, MS, University of Southern California; Cindy Duke, MD, PhD, FACOG, Nevada Fertility Institute Moderator: Dena Goldberg, MS, CGC, Dena DNA  Identify pseudoscience on social media and intervention techniques.  Evaluate the potential risks and benefits to creating personal science content for social media.  Formulate a personal strategy for science communication and content creation while staying within the confounds of institutional rules and regulations surrounding social media.  Compare the newest social media platforms and the benefits and limitations to each of them. Held in New Orleans

On-Demand Educational Breakout Sessions

OD01: Advocating for Autonomy: Genetic Counselors as Champions for Comprehensive Reproductive Health 1.5 Contact Hour Speakers: Andrew Beck, JD, American Civil Liberties Union; Laura Hercher, MA, MS, CGC, Sarah Lawrence College Joan H. Marks Graduate Program in Human Genetics; Renee Bracey Sherman, MPA, We Testify Susheela Jayaraman, MA, MS, CGC, Hawaii Community Genetics; Moderators: Katie Sagaser, MS, CGC, Johns Hopkins University School of Medicine; Patti Winters, MS, CGC, Illumina, Inc  Identify the evolution of reproductive health policy at both the state and federal levels in recent years.  Appraise the implications of reproductive health policy changes on underinsured persons and marginalized individuals presenting for genetic counseling care in various medical specialties.  Evaluate models for healthcare providers to normalize conversations about abortion as healthcare.  Strategize opportunities for genetic counselor action in reproductive justice advocacy.

OD02: Building Knowledge about Parkinson’s Disease (for the Non-Specialist Genetic Counselor) 1.5 Contact Hour Speakers: Rachel A. Paul, MS, CGC, University of Pennsylvania; Samuel Strom, PhD, Fulgent Genetics; Jeanine Schulze, MS, CGC, Indiana University; Lola Cook, MS, CGC, Indiana University; Priscila Hodges, MS, CGC, Indiana University Moderator: Jamie Fong, MS, CGC, Baylor College of Medicine  To review the clinical features of PD, diagnosis, and overlapping conditions.  To understand PD causation, become familiar with the major PD genetics, and identify educational/referral resources for PD genetics.  To review current PD genetic testing.  To explore secondary encounters with PD-associated test results.

OD03: Multidisciplinary Approaches to Hereditary Renal Cancer Identification and Surveillance 1.5 Contact Hour Speakers: Samantha Greenberg, MS, MPH, CGC, Huntsman Cancer Institute; Eric Jonasch, MD, UT MD Anderson Cancer Center; Katherine Nathanson, MD, University of Pennsylvania School of Medicine Moderator: Lindsey Byrne, MS, CGC, The Ohio State University  Describe subtypes of RCC and indications for evaluation of hereditary RCC.  Compare and contrast current guidelines (NCCN, organization-specific guidelines, and expert recommendations) to identify optimal hereditary RCC management.  Identify strategies to develop multi-disciplinary team to address hereditary RCC management.

OD04: Referral Innovation through Automation: Using Your EHR to Help Providers Recognize and Generate Appropriate Referrals through Clinical Decision Support (CDS) 1.5 Contact Hour Speakers: Brian Reys, MS, CGC, UT Southwestern Medical Center; John Zimmerman, MS, CGC, UT Southwestern Medical Center; Sara Pirzadeh-Miller, MS, CGC, UT Southwestern Medical Center; Amy Sturm, MS, CGC, Geisinger; Adam Buchanan, MS, MPH, CGC, Geisinger Health; Mark Dunnenberger, PharmD, NorthShore University HealthSystem  Summarize typical EHR referral processes and how automated clinical decision support (CDS) can be leveraged to benefit Genetic Counselors.  Identify what is needed (the EHR foundations) at a genetic counselor’s institution to implement this type of project.  Examine examples of successes and challenges when implementing EHR automation from the GC perspective.  Evaluate means of measuring CDS success.

OD05: The Latest in Pharmacogenetics: What Genetic Counselors Need to Know 1.5 Contact Hour Speakers: Megan Bell, ScM, CGC, Sanford Health; Jacquelyn Mahder, CGC, PWN Health; Stacey Detweiler, MS, CGC, 23andMe Inc.; Amisha Shah Punj, MSc, MS, CGC, Myriad Genetics, Inc.  Employ strategies for counseling for pharmacogenetics within the genetic counseling scope of practice.  Compare variable testing technologies utilized for pharmacogenetics including sequencing and genotyping.  Describe current payer coverage and patient access landscape related to pharmacogenetic testing.  Recognize the dramatic impact FDA regulation has had on PGx test offerings.

OD06: Update for the Generalist: Anticipating the Intersection of the DTC Market and Multimodal Biomarker Tests for Alzheimer's Disease (Beyond ApoE) 1.5 Contact Hour Speakers: Julio Rojas-Martinez, MD, PhD, University of California, ; Emily Largent, JD, PhD, RN, University of Pennsylvania Perelman School of Medicine; Johanna Schmidt, MPH, MGC, LCGC, Westside Genetic Counseling Moderator: Jamie C. Fong, MS, LCGC, Baylor College of Medicine  Identify the varied biomarker tests available to aid in the diagnosis of Alzheimer's disease (AD).  Identify the ethical, legal and social challenges of DTC tests (beyond APOE) for AD, and their impact on health disparities.  Identify the issues associated with medicalization of preclinical Alzheimer's disease and its impact on therapeutic approaches and genetic risk information.  List 2-3 specific actions genetic counselors can take when counseling patients about AD genetic testing in the face of new biomarker tests.

OD07: Variant Interpretation in Expanded Carrier Screening: Caveat Emptor! Elaine Sugarman 1.5 Contact Hour Speakers: Elaine Sugarman; Julia Silver, CGC, University of California San Francisco; Rawan Awwad, MS, CGC, Igenomix; Aarti Ramdaney, MS, CGC, University of Texas Health Science Center at Houston Moderator: Andria Besser, MS, NYU Langone Fertility Center  Describe the current guidelines in practice for interpretation of variants identified through expanded carrier screening.  Identify benefits, pitfalls, and limitations of these advancements using a review of the literature and case examples.  Debate the role and responsibilities of the ordering provider versus the genetic counselor versus the ECS laboratory.