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Effect of Chronic and Intermittent Calorie Restriction on Serum Adiponectin and Leptin and Mammary Tumorigenesis
Published OnlineFirst January 21, 2011; DOI: 10.1158/1940-6207.CAPR-10-0140 Cancer Prevention Research Article Research Effect of Chronic and Intermittent Calorie Restriction on Serum Adiponectin and Leptin and Mammary Tumorigenesis Olga P. Rogozina1, Melissa J.L. Bonorden1, Christine N. Seppanen1, Joseph P. Grande2, and Margot P. Cleary1 Abstract The effect of chronic (CCR) and intermittent (ICR) caloric restriction on serum adiponectin and leptin levels was investigated in relation to mammary tumorigenesis. 10-wks old MMTV-TGF-a female mice were assigned to ad libitum fed (AL; AIN-93M diet), ICR (3-week 50% caloric restriction, AIN-93M-mod diet, 2Â protein, fat, vitamins, and minerals followed by 3-wks 100% AL consumption of AIN-93M), and CCR (calorie and nutrient intake matched for each 6-wks ICR cycle, 75% of AL) groups. Mice were sacrificed at 79 (end of restriction) or 82 (end of refeeding) wks of age. Serum was obtained in cycles 1, 3, 5, 8, 11, and terminal. Mammary tumor incidence was 71.0%, 35.4%, and 9.1% for AL, CCR, and ICR mice, respectively. Serum adiponectin levels were similar among groups with no impact of either CCR or ICR. Serum leptin level rose in AL mice with increasing age but was significantly reduced by long-term CCR and ICR. The ICR protocol was also associated with an elevated adiponectin/leptin ratio. In addition, ICR- restricted mice had increased mammary tissue AdipoR1 expression and decreased leptin and ObRb expression compared with AL mice. Mammary fat pads from tumor-free ICR-mice had higher adiponectin expression than AL and CCR mice whereas all tumor-bearing mice had weak adiponectin signal in mammary fat pad. -
Effects of Chronic Vs. Intermittent Calorie Restriction on Mammary Tumor Incidence and Serum Adiponectin and Leptin Levels in MMTV-TGF-Α Mice at Different Ages
ONCOLOGY LETTERS 1: 167-176, 2010 167 Effects of chronic vs. intermittent calorie restriction on mammary tumor incidence and serum adiponectin and leptin levels in MMTV-TGF-α mice at different ages SONER DOGAN1, OLGA P. ROGOZINA1, ANNA E. LOKSHIN2, JOSEPH P. GRANDE3 and MARGOT P. CLEARY1 1Hormel Institute, University of Minnesota, Austin, MN 55912; 2University of Pittsburgh Cancer Institute, Hillman Cancer Centre Research Pavillion, Pittsburgh, PA 15213; 3Department of Pathology and Laboratory Medicine, Mayo Foundation, Rochester, MN 55905, USA Received January 28, 2009; Accepted July 31, 2009 DOI: 10.3892/ol_00000031 Abstract. Calorie restriction prevents mammary tumor (MT) was significantly reduced as mice aged, but this ratio in ICR development in rodents. Usually, chronic calorie restriction mice was significantly higher than that forad libitum and CCR (CCR) has been implemented. In contrast, intermittent calorie mice. No correlation was noted between serum adiponectin restriction (ICR) has been less frequently used. Recent studies and leptin. These findings demonstrate that intermittent calorie indicate that when a direct comparison of the same degree restriction delays the early development of MTs. This delay of CCR vs. ICR was made using MMTV-TGF-α mice which was associated with reduced serum leptin levels following the develop MTs in the second year of life, ICR provided greater restriction phases of the protocol. Additionally, serum leptin protection than CCR in delaying MT detection and reducing levels correlated with body weight and body fat in the groups tumor incidence. Adiponectin and leptin are two adipocyto- studied. kines secreted from adipose tissue which have opposite effects on many physiological functions, including proliferation of Introduction human breast cancer cells. -
Palaeolithic Diet in Diabesity and Endocrinopathies – a Vegan’S Perspective
Review Obesity Palaeolithic Diet in Diabesity and Endocrinopathies – A Vegan’s Perspective Lovely Gupta,1 Deepak Khandelwal,2 Priti Rishi Lal,1 Sanjay Kalra,3 Deep Dutta4 1. Department of Food and Nutrition, Lady Irwin College, University of Delhi, New Delhi, India; 2. Department of Endocrinology, Maharaja Agrasen Hospital, New Delhi, India; 3. Department of Endocrinology, Bharti Hospital and Bharti Research Institute of Diabetes and Endocrinology, Karnal, Haryana, India; 4. Department of Endocrinology, CEDAR Super-specialty Clinics New Delhi, India DOI: https://doi.org/10.17925/EE.2019.15.2.77 ntroduction: The Palaeolithic diet is designed to resemble that of human hunter-gatherer ancestors thousands to millions of years ago. This review summarises the evidence and clinical application of this diet in various disorders. An empiric vegan variant of it has been Iprovided, keeping in mind vegan food habits. Review of the literature: different types of Palaeolithic diets in vogue include the 80/20, the autoimmune, the lacto, the Palaeolithic vegan and the Palaeolithic ketogenic. We have developed an Indian variant of the Palaeolithic vegan diet, which excludes all animal-based foods. The Palaeolithic diet typically has low carbohydrate and lean protein of 30–35% daily caloric intake in addition to a fibre diet from non-cereal, plant-based sources, up to 45–100 g daily. In different observational studies, beneficial effects on metabolic syndrome, blood pressure, glucose tolerance, insulin secretion, lipid profiles and cardiovascular risk factors have been documented with the Palaeolithic diet. Short-term randomised controlled trials have documented weight loss, and improved glycaemia and adipo-cytokine profiles. -
Healthy Recipes from the Paleolithic Diet and Superfoods
EASY HEALTHY COOKING : HEALTHY RECIPES FROM THE PALEOLITHIC DIET AND SUPERFOODS Author: Lori Chase Number of Pages: 152 pages Published Date: 14 May 2013 Publisher: WebNetworks Inc Publication Country: none Language: English ISBN: 9781631878459 DOWNLOAD: EASY HEALTHY COOKING : HEALTHY RECIPES FROM THE PALEOLITHIC DIET AND SUPERFOODS Easy Healthy Cooking : Healthy Recipes from the Paleolithic Diet and Superfoods PDF Book Half the author's royalties will be donated to child poverty projects following the earthquakes in Christchurch, New Zealand. Content-based strategies-the commitments of practice for teaching English learners are tailored to specific content areas: English, science, social studies, and math. Andrews also played a key role in the Harlem Renaissance, supporting writers and intellectuals with dedicated workspace at her 135th Street Branch Library. About the Author At just the age of 25, Mateo is a Global Management Engineer and a Best Selling Author. Readers will also get an opportunity to get started with web based notebooks such as Jupyter, Apache Zeppelin and data flow tool Apache NiFi to analyze and visualize data. The Key Approaches to Criminology series celebrates the removal of traditional barriers between disciplines and, specifically, reflects criminology's interdisciplinary nature and focus. An included teachers' guide provides teaching suggestions for using the activities, ideas for extending the activities, and an answer key for each activity, while a CD-ROM assessment tool allows teachers to evaluate students' use of the skills covered in the book. Get it Now Before the Price Increases. Program participants have used the techniques described to develop curricula on such diverse topics as preclerkship skills building, clinical reasoning and shared decision making, outpatient internal medicine, musculoskeletal disorders, office gynecology for the generalist, chronic illness and disability, geriatrics for nongeriatric faculty, surgical skills assessment, laparoscopic surgical skills, cross-cultural competence, and medical ethics. -
Diet Manual for Long-Term Care Residents 2014 Revision
1 Diet Manual for Long-Term Care Residents 2014 Revision The Office of Health Care Quality is pleased to release the latest revision of the Diet Manual for Long-Term Care Residents. This manual is a premier publication—serving as a resource for providers, health care facilities, caregivers and families across the nation. In long-term care facilities, meeting nutritional requirements is not as easy as it sounds. It is important to provide a wide variety of food choices that satisfy each resident’s physical, ethnic, cultural, and social needs and preferences. These considerations could last for months or even years. Effective nutritional planning, as well as service of attractive, tasty, well-prepared food can greatly enhance the quality of life for long-term care residents. The Diet Manual for Long Term Care Residents was conceived and developed to provide guidance and assistance to nursing home personnel. It has also been used successfully in community health programs, chronic rehabilitation, and assisted living programs. It serves as a guide in prescribing diets, an aid in planning regular and therapeutic diet menus, and as a reference for developing recipes and preparing diets. The publication is not intended to be a nutrition-care manual or a substitute for individualized judgment of a qualified professional. Also included, is an appendix that contains valuable information to assess residents’ nutritional status. On behalf of the entire OHCQ agency, I would like to thank the nutrition experts who volunteered countless hours to produce this valuable tool. We also appreciate Beth Bremner and Cheryl Cook for typing the manual. -
The Gluten-Free Diet Epidemic: Socioeconomic Factors Predict Google Search Trends More Than Health Related Factors
Accepted Manuscript The Gluten-Free Diet Epidemic: Socioeconomic Factors Predict Google Search Trends More Than Health Related Factors Monika Laszkowska, MD, Henna Shiwani, Julia Belluz, Jonas F. Ludvigsson, MD, PhD, Peter HR. Green, MD, Daniel Sheehan, MA, Andrew Rundle, MPH, DrPH, Benjamin Lebwohl, MD, MS PII: S1542-3565(17)30928-X DOI: 10.1016/j.cgh.2017.07.042 Reference: YJCGH 55379 To appear in: Clinical Gastroenterology and Hepatology Accepted Date: 31 July 2017 Please cite this article as: Laszkowska M, Shiwani H, Belluz J, Ludvigsson JF, Green PH, Sheehan D, Rundle A, Lebwohl B, The Gluten-Free Diet Epidemic: Socioeconomic Factors Predict Google Search Trends More Than Health Related Factors, Clinical Gastroenterology and Hepatology (2017), doi: 10.1016/j.cgh.2017.07.042. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. ACCEPTED MANUSCRIPT The Gluten-Free Diet Epidemic: Socioeconomic Factors Predict Google Search Trends More Than Health Related Factors Short Title: Google Search Trends for Gluten-Free Diet Authors: Monika Laszkowska, MD 1, Henna Shiwani 1, Julia Belluz 2, Jonas F Ludvigsson, MD, PhD 1,3,4,5 , Peter HR Green, MD 1, Daniel Sheehan, MA 6, Andrew Rundle, MPH, DrPH 7, Benjamin Lebwohl, MD, MS 1,3* 1 Celiac Disease Center, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA. -
Neanderthal Diets in Central and Southeastern Mediterranean Iberia
Quaternary International 318 (2013) 3e18 Contents lists available at SciVerse ScienceDirect Quaternary International journal homepage: www.elsevier.com/locate/quaint Neanderthal diets in central and southeastern Mediterranean Iberia Domingo C. Salazar-García a,b,c,*, Robert C. Power a, Alfred Sanchis Serra d, Valentín Villaverde c, Michael J. Walker e, Amanda G. Henry a a Research Group on Plant Foods in Hominin Dietary Ecology, Max-Planck Institute for Evolutionary Anthropology, Leipzig, Germany b Department of Human Evolution, Max-Planck Institute for Evolutionary Anthropology, Leipzig, Germany c Departamento de Prehistoria y Arqueología, Universitat de València, València, Spain d Museu de Prehistòria de València, Servei d’Investigació Prehistòrica, Diputació de València, València, Spain e Departamento de Zoología y Antropología Física, Universidad de Murcia, Murcia, Spain article info abstract Article history: During recent decades, Neanderthal diet has been a major research topic in palaeoanthropology. This has Available online 18 June 2013 been accelerated by the maturation of different techniques, which have produced a plethora of new information. However, this proliferation of data has led to confusing and contradictory results. Furthermore, most of the ecological dietary studies have been carried out on specimens drawn from different time periods and regions, almost exclusively those characterized by cold, open environmental conditions. Subsistence models based on these fragmentary data have been applied to Neanderthals living in a variety of different regions and environments, even though their dietary strategies may have been as variable as regions they inhabited. In this paper we integrate different dietary approaches (studies of the zooarchaeology, stable isotopes and plant remains) from the central and southeastern Mediterranean coast of Iberia in order to develop a broader and more complex picture of Neanderthal diet in different Mediterranean environmental conditions. -
ELIMINATION DIET Comprehensive Guide
ELIMINATION DIET Comprehensive Guide Version 10 Table of Contents Why the Elimination Diet? ............... 3 Features of the Elimination Diet ...... 4 Touring Through the Food Plan ....... 8 The Reintroduction Process .......... 14 Helpful Hints .................................. 16 Frequently Asked Questions ......... 17 Resources and Tools for Success .. 19 © 2021 The Institute for Functional Medicine Why the Elimination Diet? Health concerns that have failed to respond to other treatments may improve after completing IFM’s Elimination Diet. Specific foods may be related to a long list of health conditions, including digestive problems, headaches, chronic sinus drainage, low energy, depression, mood swings, eczema, skin irritations, joint aches, asthma, weight gain, and others. Many suffer from these symptoms for long periods of time without realizing the connection to food. It isn’t until a food is eliminated from the diet, that the connection with symptoms can be made. IFM’s Elimination Diet firstly removes common food triggers, then helps you identify specific foods that may be causing ongoing symptoms through a personalized food reintroduction. After the three-week elimination period, a personalized food reintroduction is the next step. Reintroduction involves adding back one food at a time to observe whether that food causes symptoms. Foods that continue to cause symptoms (physical, mental, or emotional) are avoided for an additional three to six months, then reintroduction is attempted again. Once the body has healed, some foods which initially caused symptoms may be tolerated and added back into the diet. The Elimination Diet is a short-term food plan. Healing the gut and being able to eat a wide variety of whole foods are the ultimate goals of the Elimination Diet. -
Scientific Evidence of Diets for Weight Loss
Nutrition 69 (2020) 110549 Contents lists available at ScienceDirect Nutrition journal homepage: www.nutritionjrnl.com Scientific evidence of diets for weight loss: Different macronutrient composition, intermittent fasting, and popular diets Rachel Freire Ph.D. * Mucosal Immunology and Biology Research Center and Center for Celiac Research and Treatment, Department of Pediatrics, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts, USA ARTICLE INFO ABSTRACT Article History: New dietary strategies have been created to treat overweight and obesity and have become popular and widely adopted. Nonetheless, they are mainly based on personal impressions and reports published in books and magazines, rather than on scientific evidence. Animal models and human clinical trials have been Keywords: employed to study changes in body composition and metabolic outcomes to determine the most effective Obesity diet. However, the studies present many limitations and should be carefully analyzed. The aim of this review Weight-loss was to discuss the scientific evidence of three categories of diets for weight loss. There is no one most effec- Popular diets tive diet to promote weight loss. In the short term, high-protein, low-carbohydrate diets and intermittent Fasting Macronutrient fasting are suggested to promote greater weight loss and could be adopted as a jumpstart. However, owing to adverse effects, caution is required. In the long term, current evidence indicates that different diets pro- moted similar weight loss and adherence to diets will predict their success. Finally, it is fundamental to adopt a diet that creates a negative energy balance and focuses on good food quality to promote health. © 2019 Elsevier Inc. -
Guidelines on Standard and Therapeutic Diets for Adults
nutrients Systematic Review Guidelines on Standard and Therapeutic Diets for Adults in Hospitals by the French Association of Nutritionist Dieticians (AFDN) and the French Speaking Society of Clinical Nutrition and Metabolism (SFNCM) Marie-France Vaillant 1,2 , Maud Alligier 3, Nadine Baclet 4, Julie Capelle 5, Marie-Paule Dousseaux 4, Evelyne Eyraud 6, Philippe Fayemendy 7,8, Nicolas Flori 9, Esther Guex 10,Véronique Hennequin 11, Florence Lavandier 12, Caroline Martineau 13, Marie-Christine Morin 14, Fady Mokaddem 15, Isabelle Parmentier 16, Florence Rossi-Pacini 17, Gaëlle Soriano 18, Elisabeth Verdier 19, Gilbert Zeanandin 20 and Didier Quilliot 21,* 1 Service Diététique, CHU Grenoble Alpes, CS 10217, CEDEX 9, 38043 Grenoble, France; [email protected] 2 Laboratoire de Bioénergétique Fondamentale et Appliquée, Université Grenoble Alpes, U1055, CS 40700, CEDEX 9, 38058 Grenoble, France 3 FORCE (French Obesity Research Center of Excellence), FCRIN (French Clinical Research Infrastructure Network), CRNH Rhône-Alpes, Centre Hospitalier Lyon Sud, 165 Chemin du Grand Revoyet, 69310 Pierre-Bénite, France; [email protected] 4 Service Diététique, Pitié Salpêtrière, Assistance Publique-Hôpitaux de Paris, 47-83, Bd de l’Hôpital, Citation: Vaillant, M.-F.; Alligier, M.; CEDEX 13, 75651 Paris, France; [email protected] (N.B.); [email protected] (M.-P.D.) Baclet, N.; Capelle, J.; Dousseaux, 5 Service Diététique, Centre Hospitalier Simone Veil de Blois, Mail Pierre Charlot, 41000 Blois, France; M.-P.; Eyraud, E.; Fayemendy, P.; [email protected] Flori, N.; Guex, E.; Hennequin, V.; 6 Service Diététique, CHU de Nice Hôpital de l’Archet, 151 Route Saint Antoine de Ginestière, et al. -
Advanced Diet As Tolerated/Diet of Choice This Is for Communication Only
SVMC INTERPRETATION OF DIET ORDERS SVMC menu plans are developed using best evidenced based practice guidelines. The Clinical Diet Manual is the basis for our menu planning and patient education materials. Listed below is a brief summary of the menu plans provided by SVMC and any specifics that may differ from the Clinical Diet Manual. Our regular non select menu serves as the basis for all our menu plans and follows the Dietary Reference Intake (DRI’s/RDA’s) for our population of male 51-70 years old. Menus are designed to meet nutritional requirements specified by the 2011 update of the DRI’s from the Food and Nutrition Board, Institute of Medicine, National Academies of Science’s guidelines. This menu is then further modified to meet the specific needs of each patient based on diet order, nutritional status, food allergies, age, cultural preferences and food likes and dislikes. Current Dietary Reference Intakes recommend that Sodium intake remain less than 2300 mg per day. In order to meet their preferences and maintain intake, most diets that do not indicate a Sodium restriction will exceed this value. A sodium restriction should be ordered if needed. Due to limitations within our nutrient database (CBORD) we do not have values available to us for all nutrients. Currently our database is incomplete for: biotin, choline, chromium, molybdenum, fluoride, iodine, chloride, linoleic acid and alpha-linolenic acid and sometimes other micronutrients. Thin liquids are a default for all diets. Nectar, honey, pudding fluid consistency or fluid restriction needs to be ordered under “DIET CATEGORY”. If oral nutrition supplements (ONS) are ordered BID with meals, i.e. -
The Paleo Diet Anna Jones, Phd Rachel E
Produced by: Nutrition and Health Info Sheet: Taylor Berggren, MS Rachael Marchand, BS Adrien Barrios, BS Courtney Mitchener, BS The Paleo Diet Anna Jones, PhD Rachel E. Scherr, PhD Sheri Zidenberg-Cherr, PhD For Health Professionals Center for Nutrition in Schools Department of Nutrition University of California, Davis 2018 What is the Paleo Diet? The Paleo diet, also referred to as the Paleolithic diet, emphasizes an increased consumption of lean meat, fish, shellfish, fruit, vegetables, eggs, nuts, and seeds while excluding grains, legumes, cereals, dairy, processed foods, refined sugars and added salt.1 The Paleo diet has gained popularity all over the world, and in 2014, it was the most searched diet-related term via Google.2 This diet pattern finds its roots in our human Paleolithic ancestors who consumed foods available from their environments through hunting, fishing, and gathering. Since humans followed hunter-gatherer lifestyles for many thousands of years, the advocates of the Paleo diet claim the human body became especially well adapted to this diet.3 However, the composition of the ancient Paleolithic diet varied greatly based on geographic region.2 Critics of the contemporary Western diet postulate that the rise in chronic illnesses such as diabetes mellitus, hypertension, and cardiovascular disease, is due to the influx of processed, refined, and sodium-heavy foods made widely available to the public, and that the nutritional quality of an ancestor-based diet may have therapeutic value in the treatment of chronic disease.3,4