Anatomy of the Fascia
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1 Structure and Function of the Skin
Go Back to the Top To Order, Visit the Purchasing Page for Details 1 Chapter 1 Structure and Function of the Skin The skin is the human body’s its largest organ, covering 1.6 m2 of surface area and accounting for approximate- ly 16% of an adult’s body weight. In direct contact with the outside environment, the skin helps to maintain four essential bodily functions: ① retention of moisture and prevention of permeation or loss of other molecules, ② regulation of body temperature, ③ protection of the body from microbes and harmful external influences, and ④ sensation. To understand cutaneous biology and skin diseases, it is very important to learn the structure and functions of normal human skin. A. Skin surface The skin surface is not smooth, but is laced with multiple net- works of fine grooves called sulci cutis. These can be deep or shallow. The slightly elevated areas that are surrounded by shal- lower areas of sulci cutis are called cristae cutis. Sweat pores fed crista cutis by the sweat glands open to the cristae cutis (Fig. 1.1). The orientation of the sulci cutis, which differs depending on body location, is called the dermal ridge pattern. Fingerprints and sulcus cutis patterns on the palms and soles, which are unique to each person, are formed by the sulci cutis. Elastic fibers also run in specific directions in deeper parts of the skin, with the direction depend- aabcdefg h i j klmnopqr ing on the site. Some skin diseases, such as epidermal nevus, are known to occur along specific lines distributed over the body, the Blaschko lines (Fig. -
Penile Circular Fasciocutaneous Flaps for Complex Anterior Urethral Strictures K.J
18 Penile Circular Fasciocutaneous Flaps for Complex Anterior Urethral Strictures K.J. Carney, J.W. McAninch 18.1 Penile Fascial Anatomy – 146 18.2 Flap Anatomy – 148 18.3 Patient Selection – 148 18.4 Preoperative Preparation – 148 18.5 Patient Positioning – 148 18.6 Flap Harvest – 149 18.7 Stricture Exposure – 150 18.8 Anastomosis – 151 18.9 Postoperative Care – 152 References – 152 146 Chapter 18 · Penile Circular Fasciocutaneous Flaps for Complex Anterior Urethral Strictures Surgical reconstruction of complex anterior urethral stric- Buck’s fascia is a well-defined fascial layer that is close- tures, 2.5–6 cm long, frequently requires tissue-transfer ly adherent to the tunica albuginea. Despite this intimate techniques [1–8]. The most successful are full-thickness association, a definite plane of cleavage exists between the free grafts (genital skin, bladder mucosa, or buccal muco- two, permitting separation and mobilization. Buck’s fascia sa) or pedicle-based flaps that carry a skin island. Of acts as the supporting layer, providing the foundation the latter, the penile circular fasciocutaneous flap, first for the circular fasciocutaneous penile flap. Dorsally, the described by McAninch in 1993 [9], produces excel- deep dorsal vein, dorsal arteries, and dorsal nerves lie in a lent cosmetic and functional results [10]. It is ideal for groove just deep to the superficial lamina of Buck’s fascia. reconstruction of the distal (pendulous) urethra, where The circumflex vessels branch from the dorsal vasculature the decreased substance of the corpus spongiosum may and lie just deep to Buck’s fascia over the lateral aspect jeopardize graft viability. -
Dermoscopy of Aplasia Cutis Congenita: a Case Report and Review of the Literature
Dermatology Practical & Conceptual Dermoscopy of Aplasia Cutis Congenita: A Case Report and Review of the Literature Rasna Neelam1, Mio Nakamura2, Trilokraj Tejasvi2 1 University of Michigan Medical School, Ann Arbor, MI, USA 2 Department of Dermatology, University of Michigan, Ann Arbor, MI, USA Key words: aplasia cutis congenita, alopecia, dermoscopy, trichoscopy Citation: Neelam R, Nakamura M, Tejasvi T. Dermoscopy of aplasia cutis congenita: a case report and review of the literature. Dermatol Pract Concept. 2021;11(1):e2021154. DOI: https://doi.org/10.5826/dpc.1101a154 Accepted: September 28, 2020; Published: January 29, 2021 Copyright: ©2021 Neelam et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License BY-NC-4.0, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: None. Competing interests: The authors have no conflicts of interest to disclose. Authorship: All authors have contributed significantly to this publication. Corresponding author: Trilokraj Tejasvi, MD, Department of Dermatology, University of Michigan, 1910 Taubman Center, 1500 E. Medical Center Dr, Ann Arbor, MI 48109, USA Email: [email protected] Introduction throbbing, and point tenderness in one of the patches of alo- pecia. The alopecic patch had been present on the right pari- Aplasia cutis congenita (ACC) is a rare heterogeneous con- etal-occipital scalp since birth and has been stable in size and genital disorder characterized by focal or widespread absence appearance for years. Three other round patches of alopecia of the skin. had also been present since birth and remained asymptomatic. -
A Case of Acquired Smooth Muscle Hamartoma on the Sole
Ann Dermatol (Seoul) Vol. 21, No. 1, 2009 CASE REPORT A Case of Acquired Smooth Muscle Hamartoma on the Sole Deborah Lee, M.D., Sang-Hyun Kim, M.D., Soon-Kwon Hong, M.D., Ho-Suk Sung, M.D., Seon-Wook Hwang, M.D. Department of Dermatology, Busan Paik Hospital, College of Medicine, Inje University, Busan, Korea A smooth muscle hamartoma is a benign proliferation of INTRODUCTION smooth muscle bundles within the dermis. It arises from smooth muscle cells that are located in arrector pili muscles, Smooth muscle hamartomas (SMH) are a result of benign dartos muscles, vascular smooth muscles, muscularis proliferation of smooth muscle bundles in the dermis. SMH- mammillae and the areolae. Acquired smooth muscle associated smooth muscle cells originate from arrector hamartoma (ASMH) is rare, with only 10 such cases having pili-, dartos-, vulvar-, mammillary- and vascular wall- been reported in the English medical literature to date. Most muscles1-3. SMH is characterized by slightly pigmented of these cases of ASMH were shown to have originated from plaques that contain vellus hairs, and SMH is subdivided arrector pili and dartos muscles. Only one case was reported into two types: congenital smooth muscle hamartoma to have originated from vascular smooth muscle cells. A 21 (CSMH) and acquired smooth muscle hamartoma (ASMH)1-3. year-old woman presented with a tender pigmented nodule, ASMH is a very rare form of SMH that was first described with numbness, on the sole of her foot, and this lesion had by Wong and Solomon1 in 1985, with only such 10 cases developed over the previous 18 months. -
Gen Anat-Skin
SKIN • Cutis,integument • External covering • Skin+its appendages-- -integumentary system • Largest organ---15 to 20% body mass. LAYERS • Epidermis •Dermis Types • Thick and thin(1-5 mm thick) • Hairy and non hairy Thick skin EXAMPLES • THICK---PALMS AND SOLES BUT ANATOMICALLY THE BACK HAS THICK SKIN. REST OF BODY HAS THIN SKIN • NON HAIRY----PALMS AND SOLES,DORSAL SURFACE OF DISTAL PHALANX,GLANS PENIS,LABIA MINORA,LABIA MAJORA AND UMBLICUS FUNCTIONS • Barrier • Immunologic • Homeostasis •Sensory • Endocrine • excretory EPIDERMIS(layers) • Stratum basale or stratum germinativum • Stratum spinosum • Stratum granulosum • Stratum lucidum • Stratum corneum Type of cells in epidermis and keratinization • Keratinocytes • Melanocytes • Langerhans • Merkels cells DERMIS LAYERS---- 1.PAPILLARY • Dermal papillae • Complementary epidermal ridges or rete ridges • Dermal ridges in thick skin • Hemidesmosomes present both in dermis and epidermis RETICULAR LAYER •DENSE IRREGULAR CONNECTIVE TIISUE Sensory receptors • Free nerve endings • Ruffini end organs • Pacinian and • Meissners corpuscles Blood supply • Fasciocutaneous A • Musculocutaneous A • Direct cutaneous A APPENDAGES • Hair follicle producing hair • Sweat glands(sudoriferous) • Sebaceous glands • Nails Hair follicle • Invagination of epidermis • Parts---infundibulum, isthmus, inferior part having bulb and invagination HAIR follicle layers • Outer and inner root sheath • Types of hair vellus, terminal, club • Phases of growth— anagen, catagen and telogen Hair shaft • Cuticle •Cortex • Medulla -
The Biophysical Modeling of the Human Tegument
International Research Journal of Pharmacy and Medical Sciences ISSN (Online): 2581-3277 The Biophysical Modeling of the Human Tegument Janos Vincze, Gabriella Vincze-Tiszay Health Human International Environment Foundation, Budapest, Hungary Email address: [email protected] Abstract— Sensory organs are parts of our body, which collect and transmit information to the central nervous system about the outside world, and about the internal condition of our body. The body collects information by millions of microscopic structures, the so-called receptor cells. These can be found in almost all parts of the body, skin, muscle, joints, internal organs, in the walls of blood-vessels and in specialized organs such as the eye or the inner ear. There are numerous types of receptor cells in the skin. Some of them register mechanical stress or pressure, others the position and displacement of sensory hairs. Different stimulation cause different sensations, such as pain, tickling, hard or light pressure, heat or cold. The nerve fibres connected to the receptor transform stimuli above threshold into sequence of actions potentials. We modelling the action potential in the mathematical equation. Although our current knowledge regarding the mechanisms of pain development is incomplete, a number of pain-related phenomena have been discovered, which bear importance from both pathobiophysical and clinical aspects. Skin is an important receptive field, due to the numerous and various terminations of the cutaneous analyser which informs the nervous centres on the proprieties and phenomena that the body gets in contact with. Keywords— human tegument, hand nail, action potential, pain reception. loosing the function of one or more analysers, reach a special I. -
Introduction
Tikrit University College of Dentistry .Human Anatomy 1st y د.ﺑﺎن إﺳﻤﺎﻋﯿﻞ Introduction Anatomy: Anatomy is the study of the structures of the body. Gross anatomy: deals with those structures that can be seen without a microscope. The anatomical position:For descriptive purposes the body is always imagined to be in the anatomical position, standing erect, arms by sides, palms of hands facing forwards. Terms: Median Sagittal Plane: This is a vertical plane passing through the center of the body, dividing it into equal right and left halves. A structure situated nearer to the median plane of the body than another is said to be medial to the other. Similarly, a structure that lies farther away from the median plane than another is said to be lateral to the other. 1 cden.tu.edu.iq Tikrit University College of Dentistry .Human Anatomy 1st y د.ﺑﺎن إﺳﻤﺎﻋﯿﻞ Coronal Planes: are imaginary vertical planes at right angles to the median plane. divides the body into anterior and posterior parts. Horizontal, or Transverse, Planes : These planes are at right angles to both the median and the coronal planes. Divides the body into superior and inferior. The terms anterior and posterior are used to indicate the front and back of the body, respectively. The terms proximal and distal describe the relative distances from the roots of the limbs; for example, the arm is proximal to the forearm and the hand is distal to the forearm. The terms superficial and deep represent the relative distances of structures from the surface of the body. The terms superior and inferior represent levels relatively high or low with reference to the upper and lower ends of the body. -
Article in Press
G Model FISH-4564; No. of Pages 11 ARTICLE IN PRESS Fisheries Research xxx (2016) xxx–xxx Contents lists available at ScienceDirect Fisheries Research journal homepage: www.elsevier.com/locate/fishres Full length article 3D-Xray-tomography of American lobster shell-structure. An overview Joseph G. Kunkel a,b,∗, Melissa Rosa b, Ali N. Bahadur c a University of Massachusetts, Amherst, MA 01003, United States b University of New England, Biddeford, ME 04005, United States c Bruker BioSpin Corp., Billerica, MA 01821, United States article info a b s t r a c t Article history: A total inventory of density defined objects of American lobster cuticle was obtained by using high res- Received 16 January 2016 olution 3D Xray tomography, micro-computed-tomography. Through this relatively unbiased sampling Received in revised form approach several new objects were discovered in intermolt cuticle of the lobster carapace. Using free and 13 September 2016 open-source software the outlines of density-defined objects were obtained and their locations in 3D Accepted 23 September 2016 space calculated allowing population parameters about these objects to be determined. Nearest neigh- Available online xxx bor distances between objects allowed interpretations of structural relationships of and between objects. Several organule types are recognized by their structural outlines and density signatures. A hierarchy of Keywords: Homarus americanus organule types and distribution suggests they develop during sequential molts. New objects (stalactites, American lobster Bouligand spirals, and basal granules) are described as mineral structures with well defined morpholog- MicroCT ical character, allowing them to be recognized by their descriptive names and distributions. -
Nails in Systemic Disease
CME: DERMATOLOGY Clinical Medicine 2021 Vol 21, No 3: 166–9 Nails in systemic disease Authors: Charlotte E GollinsA and David de BerkerB A change in colour, size, shape or texture of finger- and MatrixCuticle toenails can be an indicator of underlying systemic disease. Nail plate An appreciation of these nail signs, and an ability to interpret them when found, can help guide diagnosis and management Nail bed of a general medical patient. This article discusses some ABSTRACT common, and some more rare, nail changes associated with systemic disease. Proximal nail fold Introduction Cuticle Examination of nails is a skill that, although emphasised when Matrix (lunula) revising for general medical exams, can be overlooked in day- Nail plate Lateral nail fold to-day practice. The value of noticing, understanding and Onychocorneal interpreting nail changes can positively add to clinical practice as band these signs can provide valuable clues to a diagnosis. Here we present a brief overview of selected common and rarer Fig 1. Anatomy of the nail plate. nail abnormalities associated with systemic conditions, as well as a limited explanation of the pathophysiology of some of the changes. Anatomy of the nail unit located in the distal third of the nail plate. They are caused The nail unit (Fig 1) is an epithelial skin appendage composed by damage to capillaries within the nail bed, which have a of the hardened nail plate surrounded by specialised epithelial longitudinal orientation, leading to their linear appearance. In the surfaces that contribute to its growth and maintenance.1 The nail case of bacterial endocarditis, this damage is likely to be caused by plate is formed of keratinised epithelial cells. -
Current Diagnosis and Treatment Options for Cutaneous Adnexal Neoplasms with Apocrine and Eccrine Differentiation
International Journal of Molecular Sciences Review Current Diagnosis and Treatment Options for Cutaneous Adnexal Neoplasms with Apocrine and Eccrine Differentiation Iga Płachta 1,2,† , Marcin Kleibert 1,2,† , Anna M. Czarnecka 1,* , Mateusz Spałek 1 , Anna Szumera-Cie´ckiewicz 3,4 and Piotr Rutkowski 1 1 Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie National Research Institute of Oncology, 02-781 Warsaw, Poland; [email protected] (I.P.); [email protected] (M.K.); [email protected] (M.S.); [email protected] (P.R.) 2 Faculty of Medicine, Medical University of Warsaw, 02-091 Warsaw, Poland 3 Department of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie National Research Institute of Oncology, 02-781 Warsaw, Poland; [email protected] 4 Department of Diagnostic Hematology, Institute of Hematology and Transfusion Medicine, 00-791 Warsaw, Poland * Correspondence: [email protected] or [email protected] † Equally contributed to the work. Abstract: Adnexal tumors of the skin are a rare group of benign and malignant neoplasms that exhibit morphological differentiation toward one or more of the adnexal epithelium types present in normal skin. Tumors deriving from apocrine or eccrine glands are highly heterogeneous and represent various histological entities. Macroscopic and dermatoscopic features of these tumors are unspecific; therefore, a specialized pathological examination is required to correctly diagnose patients. Limited Citation: Płachta, I.; Kleibert, M.; treatment guidelines of adnexal tumor cases are available; thus, therapy is still challenging. Patients Czarnecka, A.M.; Spałek, M.; should be referred to high-volume skin cancer centers to receive an appropriate multidisciplinary Szumera-Cie´ckiewicz,A.; Rutkowski, treatment, affecting their outcome. -
467 1.Pdf (10.98Mb)
Reduction of Biomechanical Models and Subject Specific Properties for Real-Time Simulation of Surgical Trocar Insertion By RAVI KUMAR CHANNA NAIK September 1, 2010 A thesis submitted to the Faculty of the Graduate School of The State University of New York at Buffalo in partial completion of the requirements for the degree of MASTER OF SCIENCE Department of Mechanical Engineering ACKNOWLEDGEMENTS I take this rare opportunity to thank one and all who have been the source of support, motivation and encouragement, both on the screen and tangible and behind the screen and intangible. I thank my academic research advisor Dr. Gary Dargush, committee members Dr. Andres Soom and Dr. Roger Mayne for all the support and guidance for my master’s thesis research and writing. I thank my family members, for their long and steady support and encouragement which gave me the strength and stability throughout the course my of study and research. I thank my peer friends, who have been very supportive, the source of recreations and a change in grave and stagnation periods and helped me to keep up my motivation and vigor in completing this thesis. Finally I thank God and associated holy company for giving me this opportunity to pursue my graduate studies at University at Buffalo and carry out this master’s research. ii ABSTRACT Trocar insertion is the first step in Laparoscopy, Thoracoscopy and most other micro surgery procedures. It is a difficult procedure to learn and practice because procedure is carried out almost entirely without any visual feedback of the organs underlying the tissues being punctured. -
Efficacy of Oral Micronutrient Supplementation on Linear Nail Growth in Healthy Individuals —A Randomized Placebo-Controlled Double-Blind Study
Journal of Cosmetics, Dermatological Sciences and Applications, 2020, 10, 191-203 https://www.scirp.org/journal/jcdsa ISSN Online: 2161-4512 ISSN Print: 2161-4105 Efficacy of Oral Micronutrient Supplementation on Linear Nail Growth in Healthy Individuals —A Randomized Placebo-Controlled Double-Blind Study Ferial Fanian1* , Adeline Jeudy1,2, Ahmed Elkhyat1,2, Thomas Lihoreau1,2, Philippe Humbert1,2,3 1Center for Studies and Research on the Integument (CERT), Department of Dermatology, University Hospital of Besançon, Besançon, France 2Clinical Investigation Center (INSERM CIC 1431), Besançon University Hospital, Besançon, France 3INSERM UMR1098, FED4234 IBCT, University of Franche-Comté, Besançon, France How to cite this paper: Fanian, F., Jeudy, Abstract A., Elkhyat, A., Lihoreau, T. and Humbert, P. (2020) Efficacy of Oral Micronutrient Introduction: Several studies demonstrate the effects of the oral supplemen- Supplementation on Linear Nail Growth in tations on the skin while there are limited data for their effects on the nail Healthy Individuals. Journal of Cosmetics, quality in healthy individuals. Only placebo controlled double blind studies Dermatological Sciences and Applications, 10, 191-203. could provide the reliable data considering the physiologic nail growth. Ob- https://doi.org/10.4236/jcdsa.2020.104020 jective: The objective of this study was to evaluate the efficacy of consump- tion of a micronutrient supplementation on linear nail growth and thickness. Received: September 4, 2020 Accepted: December 12, 2020 Subjects and Method: 60 healthy female volunteers aged 35 to 65 years old Published: December 15, 2020 were enrolled, randomized blindly in treatment and placebo groups, taking one tablet per day for 3 months. The evaluation was performed on D0 and Copyright © 2020 by author(s) and D90 ± 3 days by measuring the linear nail growth, nail thickness by high fre- Scientific Research Publishing Inc.