Analyst An Overview of Recent Developments in the Analytical Detection of New Psychoactive Substances (NPSs) Journal: Analyst Manuscript ID: AN-MRV-04-2015-000797.R1 Article Type: Minireview Date Submitted by the Author: 18-May-2015 Complete List of Authors: Banks, Craig; Manchester Metropolitan University, Chemistry Smith, Jamie; Manchester Metropolitan University, Chemistry Manchester, United Kingdom, Sutcliffe, Oliver; Manchester Metropolitan University, Page 1 of 41 Analyst 1 2 3 An Overview of Recent Developments in the Analytical Detection 4 5 6 of New Psychoactive Substances (NPSs) 7 8 9 10 11 12 13 14 Jamie P. Smith, Oliver B. Sutcliffe and Craig E. Banks* 15 16 17 18 19 20 Faculty of Science and Engineering, School of Chemistry and the Environment, 21 22 Division of Chemistry and Environmental Science, Manchester Metropolitan University, 23 Chester Street, Manchester M1 5GD, Lancs, UK 24 25 26 27 28 29 30 31 32 33 34 35 36 Submission to: Analyst 37 38 39 40 41 42 43 44 45 46 47 48 49 *To whom correspondence should be addressed. 50 51 Email:
[email protected]; Tel: +44(0)1612471196; Fax: +44(0)1612476831 52 53 54 55 56 57 58 59 60 1 Analyst Page 2 of 41 1 2 3 Abstract 4 5 6 Novel psychoactive substances (NPSs), sometimes referred to as “legal highs” in 7 8 more colloquial environments/the media, are a class of compounds that have been recently 9 10 made available for abuse (not necessarily recently discovered) which provide similar effects 11 to the traditional well studied illegal drugs but are not always controlled under existing local, 12 13 regional or international drug legislation.