Genetic Diversity of Norovirus in Children Under 5 Years of Age with Acute Gastroenteritis from Cambridge.Org/Hyg Angola
Epidemiology and Infection Genetic diversity of norovirus in children under 5 years of age with acute gastroenteritis from cambridge.org/hyg Angola 1, 2, 1 3 3 3 Original Paper A. Esteves *, J. Nordgren *, C. Tavares , F. Fortes , R. Dimbu , N. Saraiva and C. Istrate1 *These authors contributed equally to this work. 1Global Health and Tropical Medicine (GHTM), Unidade de Microbiologia Médica, Instituto de Higiene e Medicina 2 Cite this article: Esteves A, Nordgren J, Tropical (IHMT), Universidade NOVA de Lisboa (UNL), Lisboa, Portugal; Division of Molecular Virology, Department Tavares C, Fortes F, Dimbu R, Saraiva N, Istrate of Clinical and Experimental Medicine, Medical Faculty, Linköping University, Linköping, Sweden and 3 C (2018). Genetic diversity of norovirus in Departamento do Controlo de Doenças (DCD), Direção Nacional de Saúde Publica (DNSP), Luanda, Angola children under 5 years of age with acute gastroenteritis from Angola. Epidemiology and Abstract Infection 146,551–557. https://doi.org/ 10.1017/S0950268818000377 Norovirus (NoV) is a major cause of acute gastroenteritis (AGE). In this study, we investigated the genetic diversity of NoV strains identified in children under 5 years of age with AGE in Received: 11 October 2017 four provinces of Angola. Faecal samples from 343 children were screened for NoV by an in Revised: 11 January 2018 Accepted: 5 February 2018 house real-time PCR assay and genotyping was performed by partial capsid gene sequencing. NoV was detected in 17.4% (58/334) of the samples, with high detection rates in children <6 Key words: months old (19%) and in children aged 12–24 months (23%).
[Show full text]