University People Race in a Genetic World

Total Page:16

File Type:pdf, Size:1020Kb

University People Race in a Genetic World JOHN HARVARD’S JOURNAL sabbatical; an advisory committee is be- Just a month before FAS acted, the Na- ing formed to assist in the decanal search. tional Institutes of Health (NIH) an- University People nounced that it would become the first Overseer Leaders major research funder with an OA man- College Dean Designated Roger W. Ferguson Jr. ’73, J.D. ’79, Ph.D. date. Its previous voluntary policy led to Rosenkrantz professor of the history of ’81, former vice chairman of the Federal participation rates that hovered “between science and of African and African Reserve Board of Governors, will preside 4 and 7 percent,” explains Alexa McCray, American studies Evelynn M. Ham- over the Board of Overseers for the 2008- deputy director of Harvard Medical monds, Ph.D. ’93, will become dean of 2009 academic year. He succeeds former School’s Countway Library. (Because the Harvard College on June 1, succeeding Vassar president Frances D. Fergusson, NIH doesn’t make grants to individuals Ford professor of human Ph.D. ’73. Pauline Yu ’71, except through their institutions, the in- evolution David Pilbeam, president of the American stitutions will be responsible for tracking who has served on an in- Council of Learned Soci- authors’ compliance with the new pol- terim basis. Since 2005, eties, becomes vice chair of icy.) That policy requires that publicly Hammonds has been se- the Overseers’ executive funded papers be placed in PubMedCen- nior vice provost for fac- committee, succeeding at- tral, an OA repository of full-text articles, ulty development and di- torney William F. Lee ’72. says McCray. She adds that pending legis- versity, gaining a Univer- lation would require all federal funding sity-wide perspective on Development(s) agencies with grant budgets in excess of faculty recruiting and sup- Paul Keenan ’85 has been $100 million to adopt a policy similar to port for faculty, graduate ROSE LINCOLN/HARVARD NEWS OFFICE appointed senior associate NIH’s—making the Harvard move seem students, and postdocs Evelynn M. Hammonds dean and director of devel- prescient indeed. struggling to balance work and family opment for the Faculty of Arts and Sci- The director of MIT’s library, Anne obligations. “Those issues will always be ences (FAS). He succeeds Scott Abell Wolpert, calls the FAS open-access policy a focus for me,” she says. “I just won’t be ’72, dean for FAS development, who is “bold and visionary”—a collective action doing them for central administration.” retiring at the end of the academic year. that “allows Harvard to support its fac- Her new job has two major projects teed Linda Fates becomes associate dean for ulty.” Under the current system of schol- up: renewing the undergraduate Houses resource development for the School of arly publishing, she says, faculty mem- (see Brevia, page 69) and launching a new Engineering and Applied Sciences. And bers’ intellectual content is “freely general-education curriculum to replace a quartet of senior development o∞cers donated to private ownership.” the Core. She also wants to enrich the has been formed into a new high-level College’s arts offerings—curricular and University Principal Gifts Team: Roger otherwise—and undergraduates’ science Cheever ’67, M.L.A. ’77, associate vice Race in a education and research opportunities. president; Charles Collier, M.T.S. ’73, senior philanthropic adviser; Joe Dono- Genetic World Engineering Deanship Ends van ’72, director; and Shirley Peppers, School of Engineering and Applied Sci- director. “I am an African American,” says Duana ences (SEAS) dean Venkatesh Narayana- Fullwiley, “but in Africa, I am white.” To murti announced on February 15 that he Currier do fieldwork as a medical anthropologist would relinquish the post in September, Captains in Senegal, she says, “I take a plane to concluding a decade of service. He had in- An expert on France, a seven- to eight-hour ride. My tended to step down in 2006, but stayed primate be- race changes as I cross the Atlantic. on during transitions in University and havior and COURTESY OF RICHARD WRANGHAM There, I say, ‘Je suis noire,’ and they say, ‘Oh, Faculty of Arts and Sciences leadership to human evo- Elizabeth Ross and okay—métisse—you are mixed.’ Then I fly Richard Wrangham oversee the elevation of his unit’s status lution, Rich- another six to seven hours to Senegal, and from a division to a school (see “‘First Day ard Wrangham, Moore professor of an- I am white. In the space of a day, I can of School’ for Engineer- thropology, and Elizabeth Ross have change from African American, to métisse, ing,” November-Decem- been appointed master and co-master, to tubaab [Wolof for “white/European”]. ber 2007, page 74). SEAS respectively, of Currier House, e≠ective This is not a joke, or something to laugh faculty ranks increased July 1. The couple, who have three chil- at, or to take lightly. It is the kind of social by 50 percent during his dren, have worked extensively in recognition that even two-year-olds who tenure; graduate-stu- Uganda, where Wrangham founded the can barely speak understand. ‘Tubaab,’ dent enrollment surged. Kibale Chimpanzee Project and Ross is they say when they greet me.” STEPHANIE MITCHELL/HARVARD.NEWS OFFICE Venkatesh Narayanamurti will re- executive director of the Kasiisi Project, Is race, then, purely a social construct? Narayanamurti turn to teaching after a which supports primary schooling. The fact that racial categories change from one society to another might suggest it is. 62 May - June 2008 But now, says Fullwiley, assistant profes- DNA: the paternally inherited Y sex chro- for known Mendelian traits or conditions sor of anthropology and of African and mosome that only men carry, and mito- (such as Huntington’s disease) only a African American studies, genetic meth- chondrial DNA, which is passed exclu- fraction of people with a gene variant ods, with their precision and implied accu- sively from mothers to their children. linked to a disease actually become ill. racy, are being used in the same way that Scientists favor these markers with good Lost in the discussion about genes, she physical appearance has historically been reason: because only one parent can pass fears, are “epigenetic” influences: factors used: “to build—to literally construct—cer- them to o≠spring, they are not subject to that a≠ect gene expression but are not part tain ideas about why race matters.” recombination, the reshu±ing of genetic of one’s genetic code, such as prenatal nu- Genetic science has revolutionized biol- data that normally occurs in each genera- trition (which may influence rates of heart ogy and medicine, and even rewritten our tion. But they represent less than 1 percent disease late in life). Such biosocial fac- understanding of human history. But the of a subject’s DNA, and each tells about tors—environmental, cultural, and eco- fact that human beings are 99.9 percent only one ancestor per generation. Two nomic—can sometimes be more influential identical genetically, as Francis Collins and generations back, a customer might learn than genes. Fullwiley questions, for exam- Craig Venter jointly announced at the about one of four grandparents; three gen- Duana Fullwiley White House on June 26, 2000, when the erations back, about one of eight great- rough draft of the human genome was re- grandparents; and by 10 generations back leased, risks being lost, some scholars fear, (roughly 250 years ago), such genetic tests in an emphasis on human genetic di≠er- reference just one of the 1,024 ancestors in ence. Both in federally funded scientific re- that generation. It doesn’t take long to search and in increasingly popular prac- reach the point when, mathematically, a tice—such as ancestry testing, which often person’s ancestors start to outnumber the purports to prove or disprove membership sum total of all people who have ever lived. in a particular race, group, or tribe—ge- Nor can genetic tests verify a person’s netic testing has appeared to lend scientific race or ethnicity. Genes that a≠ect skin credence to the idea that there is a biologi- pigmentation or blood proteins involved in cal basis for racial categories. malarial resistance, the authors note, may In fact, “There is no genetic basis for not measure direct and unique ancestry race,” says Fullwiley, who has studied the (for example, a founder e≠ect), but reflect ethical, legal, and social implications of instead an evolutionary response to the human genome project with sociolo- “shared environmental exposures.” Fur- gist Troy Duster at UC, Berkeley. She thermore, the tests are based on compar- sometimes quotes Richard Lewontin, now isons to databases of DNA from living pop- professor of biology and Agassiz professor ulations, and are therefore vulnerable to of zoology emeritus, who said much the “systematic bias” because of “incomplete same thing in 1972, when he discovered geographic sampling” or the fact that “pre- that of all human genetic variation (which sent-day patterns of residence are rarely we now know to be just 0.1 percent of all identical to what existed in the past.” One genetic material), 85 percent occurs within testing company even uses an underlying geographically distinct groups, while 15 model that “reinforces the archaic racial percent or less occurs between them. The view that four discrete ‘parental’ popula- issue today, Fullwiley says, is that many tions (Africans, Europeans, East Asians, ple, if the prevalence of diabetes among Na- scientists are mining that 15 percent in and Native Americans) existed in the past” tive Americans on reservations, or of search of human di≠erences by continent. even though “there is little evidence that asthma among U.S.
Recommended publications
  • 23 Pairs in Humans That Contain Our Genes Genome: Your Entire DNA DNA: Deoxyribonucleic Acid; Contains 4 Base Pairs -Adenine, Thymine, Guanine, Cytosine
    Handout for June 20, 2020 Skagit Valley Genealogical Society DNA and Genealogy Definitions Chromosomes: 23 pairs in humans that contain our genes Genome: Your entire DNA DNA: Deoxyribonucleic Acid; contains 4 base pairs -Adenine, Thymine, Guanine, Cytosine. In various combinations these determine your genome Mitochondria DNA (mtDNA): The bodies in a cell but outside the nucleus. They provide the energy for cells to do their work. They contain some DNA. Y-Chromosome: in males only X-Chromosome: Women have two of these; men only have one in combination with a Y-Chromosome MRCA: Most Recent Common Ancestor that you share with a match Centi-Morgans (cM): a centiMorgan is a measurement of how likely a segment of DNA is to recombine from one generation to the next. The important thing to remember: The larger the number of shared cMs, the closer the relationship to a DNA match. DNA Testing Sites Ancestry.com Autosomal testing only 23andme.com Autosomal only FamilyTreeDNA.com Y-DNA, mtDNA and Autosomal MyHeritage.com Autosomal only Many others for specific testing, e.g., African Ancesotrs Blogs and Wikis The Genetic Genealogist thegeneticgenealogist.com Family Search Wiki familysearch.org/wiki The International Society of Genetic Genealogists www.isogg.com DNA Explained https://dna-explained.com More information Reference Groups See: Ancestry.com https://www.ancestry.com/corporate/sites/default/files/AncestryDNA-Matching- White-Paper.pdf MyHeritage: https://faq.myheritage.com/en/article/which-ethnicities-does- myheritage-compare-my-dna-with 23andme:
    [Show full text]
  • Exploring Identity Through Genetic and Genealogical Research: Development of a Collaborative Course Between Humanities and Biology
    Quadrivium: A Journal of Multidisciplinary Scholarship Volume 3 Issue 1 Issue 3, Spring 2011 Article 8 4-20-2011 Exploring Identity Through Genetic and Genealogical Research: Development of a Collaborative Course Between Humanities and Biology James Doan Nova Southeastern University, [email protected] Emily F. Schmitt Lavin Nova Southeastern University, [email protected] Follow this and additional works at: https://nsuworks.nova.edu/quadrivium Part of the Arts and Humanities Commons, and the Social and Behavioral Sciences Commons Recommended Citation Doan, James and Schmitt Lavin, Emily F. (2011) "Exploring Identity Through Genetic and Genealogical Research: Development of a Collaborative Course Between Humanities and Biology," Quadrivium: A Journal of Multidisciplinary Scholarship: Vol. 3 : Iss. 1 , Article 8. Available at: https://nsuworks.nova.edu/quadrivium/vol3/iss1/8 This Article is brought to you for free and open access by the CAHSS Journals at NSUWorks. It has been accepted for inclusion in Quadrivium: A Journal of Multidisciplinary Scholarship by an authorized editor of NSUWorks. For more information, please contact [email protected]. Doan and Schmitt Lavin: Exploring Identity Through Genetic and Genealogical Research: Dev About the Authors Jim Doan, Ph.D., holds a B.A. in Literature from UC—Santa Cruz, an M.A. in Folklore and Mythology from UCLA, an M.A. in Celtic Languages and Literatures, and a Ph.D. in Folklore and Celtic Studies from Harvard. Since 1988, he has taught courses in literature, the arts, folklore, and mythology at the Farquhar College of Arts and Sciences Division of Humanities. He established the Stolzenberg-Doan Endowment Fund, which supports an International Studies lecture series at NSU, as well as scholarships to allow NSU students to undertake foreign studies.
    [Show full text]
  • Dalton DNA Project Report
    1 of 7 Dalton International DNA Project Report: Update, June 6, 2019 . there is probably no person capable of the least degree of reflection, who has not, in an idle moment, amused himself with some little speculation of the probable origin of his own name. Mark Antony Lower, English Surnames: Essays on Family Nomenclature, Preface to first edition, (1842), p.viii What is DNA, this molecule that allows us to travel so far back in the past—this history book we carry around like a gift from a long line of ancestors? Spencer Wells, National Geographic, 2007, p.13 Submitted by Elizabeth (Beth) Balkite, MS, Certified Genetic Counselor Introduction 2 of 7 It has been seven (7) decades since scientists demonstrated that DNA is the molecule of heredity. Since then the only constant in the world of DNA has been change—the evolution of information about DNA. We are now at a time when new information seems to become available weekly through scientific journals, print and television, as well as social media. This report is an update from the report of 2014 for members of the Dalton Internation- al DNA Project (DIDP). It includes a summary of information and recommendations. Some of the information included is known by long term members but may be new to those who have recently joined the project. One of the biggest changes in the world of DNA testing is in the area of privacy and management of accounts at the different companies, including FTDNA. So, I have in- cluded information on this topic at the conclusion of the report with a section on Ethi- cal-Legal Social Issues for all members.
    [Show full text]
  • Dna Tests for Genealogy
    DNA TESTS FOR GENEALOGY By Ken McNaughton At the turn of this century two researchers made major contributions in the field of DNA testing for genealogy—Spencer Wells and Bryan Sykes. Spencer Wells (Fig. 1) is an American geneticist and anthropologist and explorer-in-residence at the National Geographic Society in Washington D.C. He has written two books on the subject [1, 2] and leads The Genographic Project. Attending one of his presentations [3] inspired me to read four books. Bryan Sykes (Fig. 2) is Professor of Human Genetics at the University of Oxford and founder of Oxford Ancestors Ltd., a genealogical DNA testing firm. He has written numerous books on the subject, two of which are referred to here [4, 5]. Figure 1. Spencer Wells on expedition explains the Genographic Project to village leaders in Chad (photo by David Evans). Sykes and Wells and other researchers have made so many fundamental discoveries about genetic anthropology over the last few years that many long-held ideas have been overturned. I visited the National Museum of Natural History in Washington D.C. on 23 December 2008 just after it reopened following a two-year overhaul. In the Anthropology section almost all of the displays had notices to the effect “This exhibit is out of date and is being revised.” Wells’s books concentrate on our descent from ‘Adam’ and ‘Eve’ in Africa and follow migration through the various branches—including seven in Europe—all over the world. Sykes’s books concentrate on seven maternal groups in Europe and the streams that populated Great Britain and Ireland.
    [Show full text]
  • Genome Hackers 3.0 Consegna
    UNIVERSITÀ DEGLI STUDI DI MILANO DOTTORATO IN SCIENZA E SOCIETÀ Dipartimento di Matematica Ciclo XXIII GENOME HACKERS REBEL BIOLOGY, OPEN SOURCE AND SCIENCE ETHIC SPS/08 – M-STO/05 di Alessandro Delfanti Relatore: Prof. Adam Arvidsson Coordinatore del dottorato: Prof.ssa Paola Gario A.A. 2009/2010 Table of contents Part I Ch. 1 p. 5 Introduction: cracking codes, remixing cultures Ch. 2 p. 19 Forbidden, public, enclosed, free. A history of open science and its political economy Ch. 3 p. 47 Hackers, rebels and profiteers. Scientists’ cultures and digital capitalism Part II Ch. 4 p. 75 What Dr. Venter did on his holidays. Sailing and sequencing the seas of capitalism Ch. 5 p. 91 Just another rebel scientist. Ilaria Capua and the restoration of the ethic of science Ch. 6 p. 107 We are the biohackers. DIYbio and the rise of garage biology Ch. 7 p. 125 Conclusions: how to hack a genome Bibliography p. 133 Part I 3 4 * 1* 1 Introduction: cracking codes, remixing cultures Yes, I am a criminal. My crime is that of curiosity. My crime is that of judging people by what they say and think, not what they look like. My crime is that of outsmarting you, something that you will never forgive me for. The Hacker Manifesto, 1986 Crack the code, share your data, have fun, save the world, be independent, become famous and make a lot of money. In this study I link the public image of contemporary scientists devoted to open biology to the ethics and myths of the hero of the computer revolution and of informational capitalism: the hacker.
    [Show full text]
  • Pen-On-Paper Electronics Printing Conductive Inks on Paper to Create Flexible Electronics “On-The-Fly” Greetings from Urbana
    University of Illinois at Urbana-Champaign Winter 2011 Pen-on-Paper Electronics Printing Conductive Inks on Paper to Create Flexible Electronics “on-the-fly” Greetings from Urbana At the beginning of this academic year, we welcomed a record number of new students to our department: 104 freshmen officially began their undergraduate studies in our department and 42 new Ph.D. students started their research careers with us this fall. We also accepted many transfer students from other departments that increased the number of students in the junior year core-courses and instructional laboratories to >100. We are working as quickly as possible to expand the equipment and space available in our instructional laboratories so that the educational experience of students is not negatively impacted by these large enrollments. The past few months have also brought an unprecedented level of visibility to our research accomplishments. John Rogers received the $500,000 Lemelson-MIT Prize, one of the world’s most prestigious honors for inventors. John’s work on flexible electronics for health and energy has been reported on by MSNBC, NPR, and The Economist. Paul Braun’s innovations in fast-charging battery electrodes have also attracted international attention through reporting by The Economist and the BBC. A vigorous culture of innovation is widely thought to be a key to continued economic growth in the internationally competitive era that we live in. We are justifiably proud of the tremendous impact the work of our faculty and students is having across a broad spectrum of science and technology. We are pleased to welcome outstanding new faculty and staff to the department this fall.
    [Show full text]
  • The Origin of Kurds
    Advances in Anthropology 2012. Vol.2, No.2, 64-79 Published Online May 2012 in SciRes (http://www.SciRP.org/journal/aa) http://dx.doi.org/10.4236/aa.2012.22008 The Origin of Kurds Ferdinand Hennerbichler Szellörózsa ut 45, Mosonmagyaróvár, Hungary Email: [email protected] Received February 28th, 2012; revised March 30th, 2012; accepted April 12th, 2012 Kurds are traditionally regarded as Iranians and of Iranian origin, and therefore as Indo-Europeans, mainly, because they speak Iranian. This hypothesis is largely based on linguistic considerations and was predominantly developed by linguists. In contrast to such believes, newest DNA-research of advanced Human Anthropology indicates, that in earliest traceable origins, forefathers of Kurds were obviously de- scendants of indigenous (first) Neolithic Northern Fertile Crescent aborigines, geographically mainly from outside and northwest of what is Iran of today in Near East and Eurasia. Oldest ancestral forefathers of Kurds were millennia later linguistically Iranianized in several waves by militarily organized elites of (R1a1) immigrants from Central Asia. These new findings lead to the understanding, that neither were aborigine Northern Fertile Crescent Eurasian Kurds and ancient Old-Iranian speaker (R1a1) immigrants from Asia one and the same people, nor represent the later, R1a1 dominated migrating early Old-Iranian- speaker elites from Asia, oldest traceable ancestors of Kurds. Rather, constitute both historically com- pletely different populations and layers of Kurdish forefathers, each with own distinct genetic, ethnical, linguistic and cultural backgrounds. These new insights indicate first inter-disciplinary findings in co-op- eration with two international leading experts in their disciplines, Iranologist Gernot L.
    [Show full text]
  • Report July 17, 2012
    AAAS Science and Human Rights Coalition Meeting Report July 17, 2012 View Meeting Agenda This meeting of the AAAS Science and Human Rights Coalition focused on the ways human rights intersect with the technological applications of science and engineering. Innovative uses of science and technology are reducing the digital divide, enhancing human rights online, and advancing access to medicines, clean water, education and more. Some of these advances, however, present challenges of professional responsibility for scientists, engineers and health professionals. What are the emerging opportunities to use technology and engineering to address human rights concerns? How does the “right to enjoy the benefits of scientific progress and its applications” help frame these issues? How can educators prepare students to use a human rights-based approach in their work? By exploring these questions, the aim of this meeting was to develop a better shared understanding of ways the scientific and engineering communities can tackle these issues in the future. Table of Contents Contents AAAS Science and Human Rights Coalition: The Next Frontier ................................................................. 4 Morning Plenary Session: Advancing the Right to Development through Science and Technology .......... 5 Business Meeting: Technology for Human Rights: Volunteer Opportunities .............................................. 7 Workshop on the Human Right to Clean Water and Sanitation ..................................................................
    [Show full text]
  • “What Dr Venter Did on His Holidays”: Exploration, Hacking
    New Genetics and Society Vol. 28, No. 4, December 2009, 415–430 “What Dr Venter did on his holidays”: exploration, hacking, entrepreneurship in the narratives of the Sorcerer II expedition Alessandro DelfantiaÃ, Yurij Castelfranchib and Nico Pitrellic aSISSA and University of Milan, Italy; bDepartment of Sociology and Anthropology, Federal University of Minas Gerais, Brazil; cICS, Interdisciplinary Laboratory, SISSA, Italy The Sorcerer II is the highly mediatized and spectacular Venter Institute’s ship that circumnavigated the planet between 2003 and 2006 to collect and classify marine microbial genomes. We analyze Craig Venter’s public communication activities and strategies especially focusing on the images of science and scientist he proposes: that of an eighteenth-century “savant” and nineteenth- century naturalist devoted to the exploration of new worlds, and that of the hacker, hero of informational capitalism. Emphasizing his independence from both academy and industry, but building strong alliances with both spheres and with the media, Craig Venter sails the oceans of the contemporary biotechnologies’ market, interpreting a specific typology of the relationship between science and society, enterprises, universities. Keywords: public communication of S&T; images and representations of science; genomics and the market Introduction In the past few decades the relation between science and media has found in biotechnologies an optimal laboratory field to test hypotheses on the changes in science–society interactions.1 However, we believe there is an aspect that has not been deeply explored: the birth of new hybrid figures such as scientists- Downloaded By: [University of California, Los Angeles] At: 19:59 19 November 2010 politicians, scientists-entrepreneurs who want to be part, at the same time, of both the academic community and other social groups.
    [Show full text]
  • Positive Media: an Introductory Exploration
    University of Pennsylvania ScholarlyCommons Master of Applied Positive Psychology (MAPP) Master of Applied Positive Psychology (MAPP) Capstone Projects Capstones 8-7-2012 Positive Media: An Introductory Exploration Meghan B. Keener [email protected] Follow this and additional works at: https://repository.upenn.edu/mapp_capstone Part of the American Film Studies Commons, American Popular Culture Commons, Broadcast and Video Studies Commons, Cognition and Perception Commons, Cognitive Psychology Commons, Communication Technology and New Media Commons, Film and Media Studies Commons, Game Design Commons, Instructional Media Design Commons, Interdisciplinary Arts and Media Commons, Journalism Studies Commons, Mass Communication Commons, Other Psychology Commons, Recreation Business Commons, Social Psychology Commons, and the Television Commons Keener, Meghan B., "Positive Media: An Introductory Exploration" (2012). Master of Applied Positive Psychology (MAPP) Capstone Projects. 29. https://repository.upenn.edu/mapp_capstone/29 Keener, M. B. (2012). Positive media: An introductory exploration. Master's thesis. University of Pennsylvania, Philadelphia. Advisor: M. E. P. Seligman, Ph. D. This paper is posted at ScholarlyCommons. https://repository.upenn.edu/mapp_capstone/29 For more information, please contact [email protected]. Positive Media: An Introductory Exploration Abstract Media has become an increasingly large part of our lives, and therefore plays a crucial role in our well- being. Positive psychology, the science of well-being, can be complemented through the new potentialities of media, which in many ways also seeks to improve the human experience. I create the context for a new dialogue about what "positive media" might be. By adopting a positive lens and discussing exemplars in different formats, this paper explores the ways media effectively incorporates elements of well-being.
    [Show full text]
  • 1 Proposal to Robert Wood Johnson Foundation for Investigator Award
    Proposal to Robert Wood Johnson Foundation For Investigator Award Jennifer L. Hochschild Maya Sen Harvard University July 2009 “There is in biology … a sense of barely contained expectations reminiscent of the physical sciences at the beginning of the 20th century. It is a feeling of advancing into the unknown and [a recognition] that where this advance will lead is both exciting and mysterious” (Economist 2007). We propose to focus on one aspect of that advance into the unknown – the growth of politics, values, and policies in the United States around the use of genomic science in medicine and racial identity. We will examine three emerging phenomena: (1) links between genetics-based medicine and the social practice of race, (2) links between medicine and individuals’ access to genetics-based medical testing, and (3) the impact of individuals’ access to genetic information on their racial and ethnic identity. What is government’s role in managing the relationship between genetics-based medicine and race, or between medical professionals and individuals who have attained genetic information about their own health? Should governments regulate direct-to-consumer sales of DNA tests? What ideological and partisan valences are developing around this science, and why? Most importantly, how can government (and which levels or branches of government) support genomic research while protecting citizens from potential risks? We will examine how American elected officials and policy- makers address these questions. I. Purpose and Orientation of the Study If research continues at its current breakneck pace, genomic science may change the way medicine is practiced in the United States.
    [Show full text]
  • A Y-Chromosome DNA Profile Can Provide Unique Information About the Paternal Lineage of a Particular Individual
    COMMON MALE ANCESTOR TEST 1 Genelex Laboratory #:29500-12 Participant: John Doe Purpose of Y-chromosome Analysis: A Y-chromosome DNA profile can provide unique information about the paternal lineage of a particular individual. This profile is generated when specific, individually variable regions of Y-chromosome DNA are tested using established methods. If no genetic changes (mutations) have occurred between generations, then all male descendants of a common paternal ancestor will share the same profile. When differences between individuals are identified, the likelihood of relatedness can be calculated by comparing their DNA profiles, a process commonly referred to as a Most Recent Common Ancestor Calculation (MRCA). DNA Analysis was performed for the purpose of establishing a Y-chromosome genetic profile. Through standardized, quality techniques and analysis, 24 specific genetic markers (loci) of the Y-chromosome have been analyzed, and confirmed allele values for each are presented in your certificate. A genetic profile is established by assigning the correct allele value to each of the 24 genetic locations and combining them as a unique set. This information was then referenced with current Y-chromosome haplogroup data sets and archaeological information sources to provide a description of the origins of your paternal line. Haplogroup Assignment: Based on close genetic matches found in a worldwide Y chromosome database, it appears that you belong to Haplogroup J, specifically subclade J1. Haplogroup Description: According to genetic theory, all humans descend from a man nicknamed "African Adam." This unknown man lived in Africa approximately 59,000 years ago, about 85,000 years after our common female ancestor, "African Eve." Other men of his time certainly left sons and grandsons, but African Adam was the only man in his generation whose descendants in the male line are still living today.
    [Show full text]