CERTIFICATE
This is to certify that
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany with the organizational units/sites as listed in the annex
has implemented and maintains an Environmental Management System.
Scope: Development, production and distribution of pharmaceuticals, chemical products and analytical systems.
Through an audit, documented in a report, it was verified that the management system fulfills the requirements of the following standard:
ISO 14001 : 2015
Certificate registration no. 005356 UM15 Valid from 2020-12-17 Valid until 2023-12-16 Date of certification 2020-11-18
DQS GmbH
Markus Bleher Managing Director
Accredited Body: DQS GmbH, August-Schanz-Straße 21, 60433 Frankfurt am Main, Germany 1 / 19
Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
005356 Development, production and distribution of Merck KGaA pharmaceuticals, chemical products and Frankfurter Straße 250 analytical systems. 64293 Darmstadt
Including: Real Estate GmbH Merck Performance Materials Germany GmbH Merck Healthcare KGaA
With regional offices at: Roesslerstrasse 96 64293 Darmstadt
Waldstrasse 3 64331 Weiterstadt
450237 Merck S.A. Production and distribution of pharmaceuticals Estrada dos Bandeirantes, 1099 and chemical products. Rio de Janeiro - RJ 22710-571 Brazil
450240 Merck Serono SA Production and distribution of Zone Industrielle de l´Ouriettaz pharmaceuticals. 1170 Aubonne Switzerland
450325 Merck Serono SA Development and production of Corsier-sur-Vevey pharmaceuticals. Rte de Fenil 25 1804 Fenil-sur-Vevey Switzerland
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Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
450241 Merck & Cie Production of chemical products. Weisshausmatte 6460 Altdorf Switzerland
450324 Merck & Cie Development and production of chemical Im Laternenacker 5 products. 8200 Schaffhausen Switzerland
527490 Sigma-Aldrich Chemie GmbH Development, manufacturing and distribution Industriestrasse 25 of reagents and chemicals for research, 9470 Buchs SG development, production and analytical Switzerland purposes.
530377 Sigma-Aldrich Production GmbH Development, manufacturing and distribution Industriestrasse 25 of reagents and chemicals for research, 9470 Buchs SG development, production and analytical Switzerland purposes.
514696 Merck Display Materials (Shanghai) Ltd. Design, development, manufacture and First Floor and Second Floor Area B of distribution of liquid crystal materials; 14th Building East Side and 15th building, distribution of other chemical materials. No. 211 Qinqiao Road, Free Trade Zone 201206 Shanghai P.R. China
518298 Merck Electronic Materials (Suzhou) Ltd. Production of photoresist products, edge bead No. 70, Longpu Road, Industrial Park rinse thinner, remover used for electronic 215021 Suzhou City, Jiangsu Province industry. P.R. China
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Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
543386 Merck Pharmaceutical Manufacturing Pharma manufacturing (production and (Jiangsu) Co., Ltd. package). No. 168 Hexing Road NETDA 226010 Nantong, Jiangsu P.R. China
527728 Sigma-Aldrich Biochemie GmbH Development, manufacturing and distribution Georg-Heyken-Strasse 14 of reagents for the synthesis of 21147 Hamburg oligonucleotides and other Life Science Germany Products.
240237 Merck KGaA Development, production and distribution of Mainzer Strasse 41 chemical products. 64579 Gernsheim Germany
518299 Merck Performance Materials GmbH Design and development, production and Rheingaustrasse 190 - 196 supply of photoresist and process chemicals 65203 Wiesbaden for the electronic and printing industry. Germany
505611 Merck Life Science GmbH Development, manufacture and distribution of Lilienthalstrasse 16 culture media and systems for microbiology. 69214 Eppelheim Germany
002955 Merck Schuchardt OHG Production and distribution of chemical Eduard-Buchner-Strasse 14 - 20 products. 85662 Hohenbrunn Germany
This annex (edition: 2020-11-18) is only valid in connection with the above-mentioned certificate. 4 / 19
Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
527592 Sigma-Aldrich Produktions GmbH Development and production of Riedstrasse 2 pharmaceuticals, chemical products and 89555 Steinheim analytical systems. Germany
527503 Sigma-Adrich Chemie GmbH Production and distribution of Riedstrasse 2 pharmaceuticals, chemical products and 89555 Steinheim analytical systems. Germany
450321 Merck S.L.U. Production and distribution of pharmaceuticals Polígono Industrial Merck and chemical products. 08100 Mollet del Valles (Barcelona) Spain
426638 Merck S.L.U. Development and production of Calle de Batanes No 1 pharmaceuticals. 28760 Tres Cantos (Madrid) Spain
450274 Merck Biodevelopment S.A.S. Development and production of biological 1 rue Jacques Monod molecules for therapeutic use. 33650 Martillac Cedex France
478742 Merck Santé S.A.S. Development and production of Le Pressoir Vert pharmaceuticals. 45402 Semoy France
This annex (edition: 2020-11-18) is only valid in connection with the above-mentioned certificate. 5 / 19
Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
518302 Merck Performance Materials SAS Design, production and sale of colloidal silica L'Usine de la Motte 1 Rue du Flottage 60350 Trosly Breuil France
450275 Merck Santé S.A.S. Production of chemical products. 5, rue Clément Ader 62100 Calais France
492648 Millipore S.A.S. Manufacturing of devices and media for fluid 39, Route Industrielle de la Hardt analysis and purification. 67120 Molsheim Manufacturing of water purification systems for France laboratories. Engineering of filtration equipment. Validation and scientific support to users.
450276 Merck Santé S.A.S. Production of chemical products and 10 Av. de Lattre de Tassigny distribution of pharmaceuticals. 69330 Meyzieu France
527761 Sigma-Aldrich Co. Ltd. Manufacture of custom oligonucleotides. Sales Homefield Road and support of custom biomolecules and life Haverhill, Suffolk science research products. CB9 8QP United Kingdom
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Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
505626 Millipore (UK) Ltd. Development, manufacture and sale of clinical 3 Fleming Road diagnostic products derived from biological Kirkton Campus sources products and cell culture media and Livingston reagents. EH54 7BN United Kingdom
527496 Sigma-Aldrich Co. Ltd. The manufacture of cell culture related critical T/A SAFC raw materials for the global health care Second Avenue industry. Heatherhouse Industrial Estate Irvine KA12 8NB United Kingdom
450286 P.T. Merck Tbk. Development, production and distribution of Jl. TB. Simatupang no. 8 pharmaceuticals and chemical products. Pasar Rebo Jakarta 13760 Indonesia
540290 PT Merck Chemicals and Life Sciences Sales, marketing and distribution of Life Jl. TB. Simatupang No. 8 Science and Performance Material products. Pasar Rebo Jakarta 13760 Indonesia
518300 Merck Performance Materials Pvt. Ltd. Design, development, manufacturing, Khopoli Site marketing and sales of silicon resins Survey No 109, 110, 112 Savroli Village, (polysilazanes and silazanes) and Taluka Khalapur, Dist. Raigad formulations. Maharashtra 410 203 India
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Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
501956 Merck Life Science Private Limited Manufacturing of filtration equipment and 50 A & 51, 2nd Phase, Ring Road, Peenya related products for biopharm, process Bangalore 560 058 solutions, biomonitoring, lab water, bioscience, India laboratory testing, validation and compliance services.
530393 Sigma Aldrich Chemicals Private Limited Development, manufacture, sales and # 12, Bommasandra Jigani Link Road distribution of specialty and fine chemicals. Bangalore, Karnataka State 560100 India
505619 Merck Millipore Ltd. Manufacture of filtration products for the Tullagreen pharmaceutical, food, beverage, electronic Carrigtwohill and analytical industries. Manufacture of T45 KD29 County Cork chromatography adsorbents, immobilized Ireland enzymes and other ligands for modification and purification of biomolecules.
527495 Sigma-Aldrich Ireland Ltd. The manufacture and supply of advanced Vale Road pharmaceutical intermediates and active Arklow, County Wicklow pharmaceutical ingredients and the Ireland procurement, sales and distribution of reagents and chemicals for research, development, production and analytical purposes.
450291 Inter-Lab Ltd. Development and distribution of Hakishon St. No. 18 pharmaceuticals. 81220 Yavneh 81101 Israel
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Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
527758 Sigma-Aldrich Israel Ltd. Development and manufacture of 3 Plaut St., Park Rabin biochemicals and biological reagents. Rehovot 7670603 Israel
527759 Sigma-Aldrich Israel Ltd. Development and manufacture of 13-15 Kiryat Hamada St., Har Hotzvim biochemicals and biological reagents. Jerusalem 9777613 Israel
450296 Merck Serono S.p.A. Development and production of Via Luigi Einaudi 11 pharmaceuticals. 00012 Guidonia Montecelio Italy
450311 Merck Serono S.p.A. Production of pharmaceuticals. Via della Magnolie 15 70026 Modugno (Bari) Italy
518301 Merck Performance Materials Ltd. Development and production of photoresists Shizuoka Site for IC’s and LCD’s, other electronics materials- 3330 Chihama, related chemical products (developer, thinner, Kakegawa-shi, rinse, remover, antireflective coating, adhesion Shizuoka 437-1412 promoter, insulating coating, protecting Japan coating and electronic raw materials), functional coating.
537117 Merck Serono Co., Ltd. Visual inspection and packaging of Pharma Atsugi Pharma Operations products. 4050, Nakatsu, Aikawa-machi, Aiko-gun Kanagawa 243-0303 Japan
This annex (edition: 2020-11-18) is only valid in connection with the above-mentioned certificate. 9 / 19
Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
532377 Merck Performance Materials Ltd. Development, production and distribution of Atsugi Site chemical products. 4084, Nakatsu, Aikawa-machi, Aiko-gun Kanagawa Pref. 243-0303 Japan
497387 Merck Ltd. Distribution of Life Science products. Atsugi Site 4084, Nakatsu, Aikawa-machi, Aiko-gun Kanagawa Pref. 243-0303 Japan
527893 Merck Ltd. Performance test for products, product Odaiba Site demonstration and hardware maintenance. Aomi 1-1-20, Divercity Tokyo Office tower 15F 135-0064 Tokyo, Kotou-ku Japan
532379 Merck Performance Materials Ltd. Sales of chemical products. Arco Tower 5F, 1-8-1 Shimomeguro, Meguro-ku Tokyo 153-8927 Japan
453292 Merck Ltd. Sales of Life Science products. Arco Tower 5F, 1-8-1 Shimomeguro, Meguro-ku Tokyo 153-8927 Japan
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Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
497388 Merck Ltd. Stock holding and provision of repair for Baraki Technical Center filtration products and analytical Nippon Express Baraki Air Cargo Center, instrumentation. 2526-26 Baraki Ichikawa, Chiba Pref. 272-0004 Japan
532380 Merck Performance Materials Ltd. Sales of chemical products. Osaka Site Senba Central Building 3F, 6-8 Hon-machi 2-chome, Chuo-ku, Osaka 541-0053 Japan
453297 Merck Ltd. Sales of Life Science products. Osaka Site Senba Central Building 3F, 6-8 Hon-machi 2-chome, Chuo-ku, Osaka 541-0053 Japan
497390 Merck Ltd. Laboratory testing, validation and compliance Yokohama Technical Center services. YBP West Tower 2F, 134 Godo-cho, Hodogaya-ku Yokohama, Kanagawa Pref. 240-0005 Japan
426640 Merck Performance Materials Ltd. Development, manufacture and distribution of Onahama Site chemical products. 51-15 Izumimachi Kurosuno Aza Egoshi Iwaki-shi, Fukushima 971-8184 Japan
This annex (edition: 2020-11-18) is only valid in connection with the above-mentioned certificate. 11 / 19
Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
505622 Merck Performance Materials Ltd. Development, production and distribution of 306, Pyeongtaekhang-Ro, Poseung-eup pharmaceuticals and chemical products. Pyeongtaek-shi, Gyeonggi-do 451-822 Republic of Korea
518304 Merck Electronic Materials Ltd. Research, development, production, 50-14 Hyupdongdanji-gil, Miyang-myeon inspection and testing of light-sensitive Anseong-si, Gyeonggi-do 17600 materials and related processing chemicals for Republic of Korea semiconductor industry.
547576 Versum Materials, Banwol Manufacture and transfill of specialty gases Jangjagol Ro, 82, 425-833 Danwon-gu, and chemicals. Ansan-si, Gyeonggi-do, Republic of Korea
547582 Versum Materials, US LLC Ansan Design and assembly of equipment to control #283, Haebong-Ro, Danwon-gu limited distribution of gases and chemicals. Ansan-Si 425-839 Republic of Korea
547591 Versum Materials, US LLC Shihwa Manufacture and transfill of specialty gases Shiwa Ind., Complex and chemicals. 143, Hyeomnyeok-ro Siheung-si 429-450 Republic of Korea
547580 Versum Materials, US LLC Gyeonggi-do Production of high purity chemicals. 88-19, Sandan-ro Pyeongtaek-si, 459-040 Republic of Korea
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Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
547595 Versum Materials, US LLC Ulsan Manufacture and transfill of speciality gases 48, Yonyeon-ro 98 beon-gil and chemicals. Nam-gu 680-150 Republic of Korea
507107 Merck S.A. de C.V. Production and distribution of Calle 5 No. 7 Fracc. Ind. Alce Blanco pharmaceuticals. 53370 Naucalpan de Juárez, Estado de México, Mexico
506584 Merck, Inc. Marketing, sales and distribution of 24/F GT Tower International, pharmaceutical drugs, chemical products and 6813 Ayala Avenue laboratory supplies and equipment. 1227 Makati City, Metro Manila Philippines
527491 SAFC Hitech Taiwan Co., Ltd. Manufacture of chemicals for industrial No. 15, Luke 3rd Rd. applications for optoelectronics and Kaohsiung Science Park semiconductor devices. Luzhu Dist. 82151 Kaohsiung City Taiwan
518305 Merck Performance Materials Ltd. Development and manufacture of photo-resist No. 458-6, 8 & 11, Xinxing Rd., products, top-layer anti-reflective coating Hu Kuo Township materials and other chemical products. Hsinchu County Taiwan
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Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
547592 Versum Materials, US LLC Taichung Provision of logistic and delivery services of Branch Office associated specialty gases and chemicals for No. 6, Dachen S. Road the electronic industries. Wuci District Taichung City Taiwan
547587 Versum Materials, US LLC Nanke Manufacture and transfill of specialty gases Sita A, No. 772, Singnong Road, and chemicals. Shanhua District, Tainan 74160 Taiwan
426643 Merck Performance Materials Ltd. Development, production and distribution of No. 39, 39-1, Ching Chien 1st Road chemical products. Kuan Yin Industrial Park Taoyuan Taiwan
478744 EMD Serono Research Cent. Development and production of 45A Middlesex Turnpike, pharmaceuticals. Bedford Campus Billerica, MA 01821, United States of America
547577 Versum Materials, US LLC Manufacture and transfill of specialty gases 357 Marian Avenue and chemicals. Tamaqua, PA 18252 United States of America
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Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
547585 Versum Materials, US LLC Catoosa Manufacture and transfill of specialty gases 1115 West Keystone and chemicals. Catoosa, OK 74015 United States of America
547586 Versum Materials, US LLC Dallas Production of High Purity Chemicals. 8201 S. Central Express Way Dallas, TX 75241 United States of America
547593 Versum Materials, US LLC Tempe Manufacture Chemical Mechanical 8555 South River Parkway Planarization and Polishing Solutions. Tempe, AZ 85284 United States of America
547584 Versum Materials, US LLC Carlsbad Manufacture of high purity materials and 1969 Palomar Oaks Way related containers. Carlsbad, CA 92011 United States of America
505631 EMD Millipore Corp. Design and development, manufacture and 28820 Single Oak Drive distribution of research kits and chemicals. Temecula, CA 92590 United States of America
450330 EMD Performance Materials Corp. Design and development, manufacture and 110 EMD Blvd. distribution of pigments. Savannah, GA 31402 United States of America
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Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
496589 EMD Millipore Corp. Design, development, manufacturing and 195 W. Birch Street distribution of Highly Purified Blood Proteins Kankakee, IL 60901 and Biologically Active Factors. United States of America
527748 SAFC Biosciences, Inc. Development, production and distribution of 13804 West 107th Street pharmaceuticals, chemical products and Lenexa, KS 66215 analytical systems. United States of America
527489 EMD Performance Materials Corp. Design, development and manufacture of high 1429 Hilldale Avenue purity chemicals for industrial applications Haverhill, MA 01832 such as optoelectronics and semiconductor United States of America devices.
496587 EMD Millipore Corp. Design, Development and Manufacture of 17 Cherry Hill Drive disposable bioprocessing systems Danvers, MA 01923 United States of America
With associated organizations:
-54 Cherry Hill Drive, Danvers, MA 01923, USA -75 Sylvan Street Warehouse, Danvers, MA 01923, USA
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Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
527743 Sigma-Aldrich Corporation Design, development, manufacturing, testing, 3500 Dekalb Street QA, warehouse, maintenance of chemical St. Louis, MO 63118 reagents, raw materials, and components. United States of America Exclusions: With associated organizations: 1. Equipment and systems owned by customers and used for custom 3300 S 2nd St, St. Louis, MO 63118 manufacturing. 3500 S Broadway, St. Louis, MO 63118 2. Sites managed by contractors or other third 545 S Ewing Ave, St. Louis, MO 63103 parties and not directly controlled by Millipore 2909 Laclede Ave, St. Louis, MO 6310 Sigma. 3050 Spruce St, St. Louis, MO 63103 2425 S 2nd St, St. Louis, MO 63104
492647 EMD Millipore Corp. Manufacture, storage and distribution of 11 Prescott Road membranes, purification systems and filtration Jaffrey, NH 03452 products for bioprocess, healthcare and United States of America beverage industries.
518306 EMD Performance Materials Corp. Design and manufacture of photoresist and 70 Meister Avenue related chemical products. Branchburg, NJ 08876 United States of America
527764 Research Organics LLC., dba SAFC Manufacturing of high purity bio-chemicals. 4353 East 49th Street Cleveland, OH 44125 United States of America
505606 EMD Millipore Corp. Development, production and distribution of 2828 Highland Avenue chemical products. Norwood, OH 45212 United States of America
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Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
527733 Sigma-Aldrich Corporation Development, procurement, production, 3858 Benner Road testing and sales of chemicals, reagents and Miamisburg, OH 45342 laboratory equipment for research, United States of America development, production and analytical purposes.
527767 Supelco, Inc. Design, development, manufacture, 595 North Harrison Rd. distribution and technical support of sample Bellefonte, PA 16823 handling, chromatography and analytical United States of America supplies and services.
518307 EMD Performance Materials Corp. Manufacturing and development of colloidal 788 Chert Quarry Rd. silica. Martin, SC 29836 United States of America
527766 Sigma-Genosys of Texas LLC Manufacture and distribution of custom Dba Sigma Custom Products oligonucleotides and peptides for the 9186 Six Pines Drive, Suite 100 Research and Applied Science Markets. The Woodlands, TX 77380 United States of America
527762 Cerilliant Corporation Development, production and distribution of 811 Paloma Drive, Suite A high quality certified reference standards and Round Rock, TX 78665 certified components for test kits. United States of America
527739 Aldrich Chemical Co., LLC. Shipping and receiving, material management, 5485 County Highway V manufacturing, packaging, quality control, Sheboygan Falls, WI 53085 maintenance, and waste management. United States of America
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Annex to certificate Registration No. 005356 UM15
Merck KGaA
Frankfurter Strasse 250 64293 Darmstadt Germany
Location Scope
527738 Aldrich Chemical Co., LLC Development, procurement, production, 6000 North Teutonia Avenue testing, sales and distribution of chemicals, Milwaukee, WI 53209 reagents and laboratory equipment for United States of America research, development, production and analytical purposes.
533209 SAFC, Inc. Support, development and manufacturing of 645 Science Dr. high-potency API (HPAPI) and highly active Madison, WI 53711 and complex pharmaceutical ingredients. United States of America
With associated organization:
1101 Kettle Moraine Tr. Verona, WI 53593 United States of America
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