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March 14, 2014 Joann Taie Executive Director Organization for Human

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March 14, 2014 Joann Taie Executive Director Organization for Human Vermont Center for Children, Youth, & Families James J. Hudziak, M.D., Director Professor of Psychiatry, Medicine and Pediatrics PHONE (802) 656-1084 FAX (802) 847-7998 Email: [email protected] March 14, 2014 JoAnn Taie Executive Director Organization for Human Brain Mapping (OHBM)Organization for Human Brain Mapping Glass Brain Award REGARDING: Nomination of Dr. Alan Evans for The Glass Brain Award Dear Selection Committee: It is a true honor to write a letter of support for Dr. Alan Evan’s nomination for the OHBM Glass Brain Award. I understand it is the special intention of the committee to award special scholars who have contributed to the mission of OHBM, who have made extraordinary contributions to the field of human brain mapping, is over 40, and will be in Hamburg (This nominee will be). I can think of no scholar more deserving for the Glass Brain Award than Professor Alan Evans. A review of his qualifications for this award is very time consuming. I apologize for the long letter. Dr. Evan’s has contributed mightily in both the technical and tactical arenas of human brain mapping, particularly in the areas of understanding the etiopathology and treatment of a wide variety of brain disorders. I will do my best to do justice to his accomplishments but suffice it to say that in my mind Dr. Evan’s is the single most important brain scientist in the world. Now let me try to defend that statement. First a review of Professor Evan’s CV is breathtaking. His over 450 peer-reviewed publications in the very best journals in the world is a good place to start. The fact that his work has been referenced over 43,000 times provides substrate for the generalizability of his work. His h-index of over 104 puts him in the top 1% of 1% of all research scholars. Moving to a more microscopic review of his career contributions. The study of brain science remains a relatively young field. Prior to understanding what is abnormal, what is disease and illness, requires an understanding of what is normal and what is well. Dr. Evans and his extended team have contributed to advancing the technical aspects of human brain mapping via image acquisition and analyses (more on this later). Without his technical contributions I doubt the field of neuroimaging would be where it is today. Next, Dr. Evans has contributed to a better understanding of normal. In fact, he has published high science on the senses of sight, smell, hearing, taste, pleasure, self perception, gender, IQ, normal development from birth to old age, appreciation of music, pitch both perfect and otherwise, and consciousness. I would argue that this work was essential to understand etiopathology. Professor Evan’s has set the standard in the study of disease as well. He has published on an exhaustive array of papers on disorder based human brain mapping. To list a few, epilepsy, stroke, MS, Alzheimers disease, Parkinson’s disease, tumors of the brain, pain, general memory disorders, Huntingtons disease, Fragile X, Fetal Alcohol Syndrome, schizophrenia, depression, alcoholism, psychosis, and Autism Spectrum Disorder. Each of these investigations have directly led to additional research science not only at the understanding of the evolution of disease, but also in the development of new treatment approaches. Professor Evan’s also has published extensively in the use of brain mapping in the treatment literature. He is 1 1 involved in understanding the brain science of drug treatment, drug development, neurosurgery, transcranial magnetic stimulation, and epigenetic effects of environmental mediation. In short, Professor Evan’s body of work includes developing the technical approaches to the study of the brain, the study of normal brain development, the understanding of etiopathology, and treatment. Given all of these achievements one would think that Dr. Evan’s would be satisfied with what he has already accomplished, and nothing could be further from the truth. Dr. Evan’s has been prescient in his understanding that to truly understand the human brain, development, illness, resilience and recovery, the field will need massive data sets and big data approaches to dealing with these data. His internationally renowned work on the “Big Brain” has not only drawn a great deal of attention to the important of brain science, it has also changed the way in which medical schools and graduate schools around the world teach neuroanatomy. He not only shares his discoveries, it is in his DNA. His creation of CBRAIN, LORAS, and CIVIT and his international reputation for sharing his big data pipelines has allowed many of us the possibility to investigate brain based disorders on sample sizes far larger than we ever dreamed. He continues to push the envelope in creating larger, collaborative, sharing scientific communities all aimed at one greater good, the discovery and treatment of brain-based disorders. He is rare in the characteristic of being a creative selfless genius. Finally, Professor Evan’s strongly supports the mission of OHBM. In fact it was his encouragement that led to my teams from both the US and Europe to attend, submit science to, and present at OHBM. Professor Evan’s is an ideal candidate for the Glass Brain Award. It will be a joy to follow the next stages of this exceptional man’s terrific career. Sincerely, James J. Hudziak, M.D. Professor, Psychiatry, Medicine & Pediatrics Director, Vermont Center for Children Youth & Families Thomas M. Achenbach Chair in Developmental Psychopathology UVM College of Medicine Visiting Professor, Sophia Children’s Hospital, ErasmusMC, Rotterdam Adjunct Professor (Child) Psychiatry, Washington University, St. Louis Adjunct Professor (Child) Psychiatry, Dartmouth, Hanover 2 2 Curriculum Vitae ALAN EVANS PhD James McGill Professor of Neurology/Neurosurgery, Psychiatry, Biomedical Engineering Montreal Neurological Institute, McGill University Founder, Biospective Inc. NAME EVANS Alan Charles BIRTHDATE October 7th, 1952 BIRTHPLACE Barry, Wales, U.K. CITIZENSHIP British ; Canadian ADDRESS 2056 Grey Ave., MONTREAL H4A 3N4, Quebec FAMILY Married (Karen) ; three children (Catherine, Meaghan, Leigh) TELEPHONE Work: 514-398-8926 ; Cell: 514-984-6919 ; Home: 514-487-6365 ACADEMIC TRAINING 1971-1974: B.Sc. 1st Class Honours, Physics, Liverpool University B.Sc. General Mathematics, Liverpool University 1974-1975: M.Sc. Medical Physics, Surrey University Thesis: “ Negative Pions in Radiotherapy " 1975-1978: Ph.D. Biophysics, Leeds University Thesis: “ The development and application of an interactive computer graphics system in the study of protein structure " CAREER EXPERIENCE AND RESEARCH INTERESTS 1978-1979: Post-doctoral Fellow: Dept. of Biophysics, Leeds University Development of an interactive computer graphics system for 3-D protein structural studies. 1979-1984: Physicist: PET program, Atomic Energy of Canada Ltd. Research and development of physics, reconstruction, physiological kinetics and software aspects of Therascan 3128 PET scanner. 1984-1990: Assistant Professor, Dept. of Neurology/Neurosurgery, McGill U. 1988-1990: Assistant Professor, Medical Physics Unit, McGill U. 1988-1994: Co-director, NeuroImaging Laboratory, McConnell Brain Imaging Centre, Montreal Neurological Institute (MNI) 3-D computerized brain atlas ; 3-D MRI/PET image correlation 1989-1994: Head, Tomograph Facility, Positron Imaging Laboratories, McConnell Brain Imaging Centre, MNI 1990-1995: Associate Prof., Dept. of Neurology/Neurosurgery, Dept. of Biomedical Engineering, Medical Physics Unit, McGill U. 1993-1994: Acting Coordinator, McConnell Brain Imaging Centre, MNI 1994-1999: Coordinator, Positron Imaging Laboratories, MNI Coordinator, McConnell Brain Imaging Centre, MNI 1995-present: Professor, Dept. of Neurology/Neurosurgery, Dept. of Biomedical Engineering, Medical Physics Unit, McGill U. Associate Member., Dept. of Electrical Engineering, McGill U. 2000-present: Director, Montreal Consortium for Brain Imaging Research 2000-present Founder, Biospective Inc (http://www.biospective.com) RESEARCH STATISTICS (as of August 2013) h-index: 104 3 3 Citations: 42,479 Peer-reviewed journal publications: 445 4 4 GRANT SUPPORT Past operating/equipment/maintenance/equipment Grants: Canadian Medical Research Council: AM Hakim, AC Evans and CJ Thompson “ New Generation Positron Emission Tomograph" $ 1,000,000 major equipment grant - 1987 Philips Medical Systems: AC Evans and TM Peters “ Pegasus project - Evaluation of 3-D imaging workstation " $ 175,000 US major equipment grant - 1988 Canadian Medical Research Council Special Project Grant SP-30: AC Evans and E Meyer “ Positron Imaging of Neural Systems - Methodology " $333,810 p.a. for five years 1993 + 255,049 equipment Canadian Medical Research Council: “ The functional neuroanatomy of cognitive processes studied by positron emission tomography " D Bub, AC Evans, H Chertkow $ 75,500 p.a. for 3 years, 1991-94 McDonnell-Pew Program in Cognitive Neuroscience: B Milner, M Petrides, B. Alivisatos, D Bub, AC Evans, A Gjedde, E Meyer, A Olivier, D Pandya, L Petito, M Seidenberg, R Zatorre “ Proposal to establish a cognitive neuroscience center at the Montreal Neurological Institute " $300,000 p.a. for five years, 1990-95 Canadian Medical Research Council Maintenance Grant: AC Evans and TM Peters “ Three-dimensional NeuroImaging " $ 70,375 p.a. for 3 years 1992-1995 + $64,697 equipment Canadian MRC Operating Grant TM Peters, AC Evans, A Olivier “ Imaging for frameless stereotaxy" $ 76,700 p.a. for three years 1992-95 Canadian MRC Equipment
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