marine drugs Article Marine Transcriptomics Analysis for the Identification of New Antimicrobial Peptides Baptiste Houyvet 1,2,3, Yolande Bouchon-Navaro 1,4, Claude Bouchon 1,4, Erwan Corre 5 and Céline Zatylny-Gaudin 1,2,* 1 Biologie des Organismes et Ecosystèmes Aquatiques (BOREA) Muséum National d’Histoire Naturelle, Sorbonne Université, Université de Caen-Normandie, Université des Antilles, CNRS-8067, IRD 207, 75231 Paris, France;
[email protected] (B.H.);
[email protected] (Y.B.-N.);
[email protected] (C.B.) 2 BOREA, Normandie University, University of Caen-Normandy, Esplanade de la Paix, CEDEX, 14032 Caen, France 3 SATMAR, Société ATlantique de MARiculture, Research and Development Department, 50760 Gatteville, France 4 Laboratoire d’Excellence “CORAIL”, Université des Antilles, Campus de Fouillole, BP 592, Pointe-à-Pitre, 97159 Guadeloupe, France 5 Plateforme ABiMS, Station Biologique de Roscoff, CNRS-Sorbonne Université, 29688 Roscoff, France;
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[email protected] Abstract: Antimicrobial peptides (AMPs) participate in the immune system to avoid infection, are present in all living organisms and can be used as drugs. Fish express numerous AMP families including defensins, cathelicidins, liver-expressed antimicrobial peptides (LEAPs), histone-derived peptides, and piscidins (a fish-specific AMP family). The present study demonstrates for the first time the occurrence of several AMPs in lionfish (Pterois volitans). Using the lionfish transcriptome, Citation: Houyvet, B.; we identified four transcript sequences encoding cysteine-rich AMPs and two new transcripts Bouchon-Navaro, Y.; Bouchon, C.; Corre, E.; Zatylny-Gaudin, C. Marine encoding piscidin-like peptides. These AMPs are described for the first time in a species of the Transcriptomics Analysis for the Scorpaenidae family.