ST ADLER GENETICS SYMPOSIA Volume 9

UNIVERSITY OF MISSOURI

AGRICULTURAL EXPERIMENT STATION

Edited by G.P. Redei

This book may not be reproduced, in whole or in part, except by reviewers for the public press, without written permission from the publisher.

LIBRARY OF CONGRESS CATALOG CARD NUMBER 79-635774

International Standard Book Number (Vol. 9) 0-912630-08-6

The STADLER GENETICS SYMPOSIA volumes are published by the Missouri Agricultural Experiment Station 117 Curtis Hall University of Missouri Columbia MO 65201 USA and may be purchased directly or through booksellers. The price of this volume is $5.50. Please remit also 50¢ for postage and handling. Missouri residents must pay an additional 22¢ for sales tax. Account Number 9738-2225 UNIVERSITY OF MISSOURI

AGRICULTURAL EXPERIMENT STATION

STADLER GENETICS SYMPOSIA Volume 9

Edited by G.P. Redei

Columbia, Missouri 1977 2 STADLER SYMP . Vo l . 9 ( 1 977) Un i versity of Mi ssouri, Columbia

ACKNOWLEDGMENTS

The 9th Stadler Gene t ics Symposi um was f i nan ced by the Department of Agronomy , the Division of Bi o log i cal Sciences , the Graduate School and the School of Medicine of the University of Missouri- Columbia . The lecture of Dr . J. R. S. Fincham was made possible by the Donald M. Nelson Fund . The lectures of Dr . Winston J . Brill and Dr . S . G. Wildman were sponsored by the U. S. Department of Agri culture , Agri cultural Research Ser vice , Mid- Plains Area . The Genetics Facul ty and Students gratefully acknow ledge all the moral and financial support which make these annual Symposia possible .

We are much indebted to Chancellor Herbert W. Schooli ng and Mrs . Bess Schooling for the hospital ity extended to us in their residen ce . Mrs . School ing made the arrangements for the reception from the hospital where she died a few days after the Symposium. All who knew her will keep her memory.

The participants wish to express thei r thanks to Mrs. Mary Kay Doyle and to other wives of the Genetics Faculty who organized t h e social program with much success .

We owe grat i tude to Dr . Richard Hills, Professor of Mus i c, and to the Woodwind Quintet for the f i ne entertain ment provided at the banquet .

Much appreciati on is due to Professor W. Q. Loegering who coordinated the Friday afternoon program wi t h the assis tance of the graduate students . Spec i al thanks are due to Larry Dardick, David Estervi g, Ken Leto and Gary Peterson, who were in charge of the projection and earned the compli ments of all the speakers . Larry Dardick a l so p r oved t o be the competent photographer of the Symposium .

Barbara Kuyper provided expert and most conscientious editorial assistance . Maribeth Jackson typed or retyped several of the manuscripts wi th patience and care. She and Dr . Gregoria Acedo worked hard behind the scenes to keep the year- around business in line .

Dr . Ruth Kavenoff was the first contributor to the E . R. Sears Scholarship Fund , established by Dean Emeritus John H. Longwell and Mrs . Lo r na Longwell.

During the year Dr . E . R. Sears was e l ected Honorary Member to the American Association of Cereal Chemists , Presi dent of the Genetics Society of America and rece i ved the Awa r d of Excellence of the Geneti cs Soci ety of Canada. Dr . Marcus Zuber was reci pient of the Crop Science Awa rd of the Cr op Science Society of Ame rica . STADLER SYMP. Vol. 9 (1977) University of Missouri, Co lumbia 3

R. S eaM S c__ho laM h,lp Fund The. E1Lne6;t R. Se.a.M Sc.hola;v.,/up Fund, u:tabwhe.d blf De.an Eme!U-tlv., John H. Longwe.ll and MM. LO!Lna Long1•;e,ll , ,i,/2 in ;te.nde.d ;to 1.,,timula;te_ ILe6e.atLc.h and 1.,c_lwla;v.,hip in Ge.rtWC,,6 in ;the. 1.,pitLi;t o{i ;the. c.onrubutioYl-6 {iOIL VIL. Se_a;v., to 1.ic.ie.nc.e., v.,1., e.n.t:.i..al ;to ;the. de.ve.lopme.n;t o 6 AgtLic.u.LtMe.. The. divide.ndJ.i 06 ;the. Fund will be. w.,e.d ;to -6uppotL;t and ILe.c.ognize. a glLadua;te. 1.,;tude.n.,t OIL 6ac.ultlf me.mbe.tL 60'1. 1.,c_hola1L6hip and ILUe.atLc.h in Ge.nWC,J.,.

The. Fund ,i,/2 admi,Y[,(,6;te.tLe.d blf ;the. Se.a;v.,-Longwe.ll AwatLd Comm,U ;te.e.. The. annual awaJtdJ.i will be. plLU e.n;te.d at the. S:tadle.tL Ge,ne_;t,{_C,,6 Stjmpo1.iia.

I 6 lfOU would Uke. ;to join in ;thiJ., e.xp1LU-6ion honotLing VIL. Se.alL6, ple.Me. -6e.nd LfOW1. c.onrubu;tion ;to:

ERNEST R. SEARS FUND 117 Curtis Hall University of Missouri Columbia, Missouri 65201

05823 4 STADLER SYMP. Vol. 9 (1977) University of Missouri, Co lumbia STADLER GENETICS SYMPOSIA 5 CONTENTS VOLUME 9 (1977)

Acknowl edgements 2 The E . R. Sears Schol arship Fund i n Genetics 3 Contents 5 List of Participants at the 9th Symposium 6

James W. All en, Charles F . Shuler , and Samuel A. Latt EXTENSION OF BrdU- DYE ANALYSIS OF DNA REPLI CATION AND SISTER CHROMATID EXCHANGE FORMATION TO IN VIVO SYSTEMS 9

G. Gavazzi THE GENETIC COMPLEXITY OF THE R LOCUS IN MAIZE 37

James N. Thompson, Jr. ANALYSIS OF GENE NUMBER AND DEVELOPMENT I N POLYGENIC SYSTEMS 63 Hirofumi Uchimi ya , Kevin Chen and S . G. Wi ldman POLYPEPT I DE COMPOSIT I ON OF FRAC TION I PROTE I N AS AN AID IN THE STUDY OF PLANT EVOLUTION 83

Donal d L. Riddl e A GENET I C PATHWAY FOR DAUER LARVA FORMATION IN CAENORHABDITIS ELEGANS 101

Moshe Fel dman HISTORICAL ASPECTS AND SI GNIFICANCE OF THE DI SCOVERY OF WILD WHEATS 121

Winston J . Bri ll GENET I CS OF NI TROGEN FI XAT I ON 147

Ruth Kavenoff and Brian C. Bowen ON THE ORGANIZAT I ON OF DNA IN I SOLATED BACTERIAL CHROMOSOMES 159

J. R. S. Finch am A GENE - ENZYME RELAT I ONSHIP IN NEUROSPORA 169

Gary Stein, Janet Stei n , Lewis Kleinsmith, Wi lliam Park, Judi th Thomson , Robert Jansi ng , Eli zabeth Shephard, and Si egfried Detke CHROMATIN AS A MODEL SYSTEM FOR STUDYING THE REGULATION OF HI STONE GENE EXPRESSION IN MAMMALIAN CELLS 179 Cumul ative Contents of the Proceedings of the Stadl er Genetics Symposia 21 5 Missouri Agricultural Experiment Station Columbia MO 65201 6 STADLER SYMP. Vol. 9 (1977) University of Missouri, Columbia

PARTICIPANTS

Maheran Abubakar, 220 Curtis, U. of Missouri, Columbia, MO 65201 Gregoria Acedo, 117 Curtis , U. of Missouri, Columbia, MO 65201 Camille Agagnon , P. 0 . Box 2977, Columbia , MO 65201 C. W. Alexander, USDA -ARS, 800 N. Providence, Columbia, MO 65201 J. W. Allen, Harvard Medical School, Boston, MA 02115 Arthur Ayers> 24 01 W. Broadway , Apt. 212, Columbia, MO 65201 Zaniel Bahari, 701B University Village, Co lumbia, MO 65201 Zeno Bailey, Route 1, Charleston , Illinois 61920 Grace Louise Baker, 408 N. 9th, Columbia, MO 65201 Helen Waiches Baker, 115 Clinton Drive, Columbia , MO 65201 Mary Ball, Auburn University, Auburn, AL 36830 Sister Rose Bast, 320 E. Ripa, St . Louis, MO 63125 Dorothy Beckett, 607 Longfellow Lane, Columbia, MO 65201 Jack Beckett, 209 Curtis, U. of Missouri, Columbia, MO 65201 Susan Bell-Smith, 206 Fine Arts, U. of Missouri, Columbia, MO 65201 Charles Biggers, Memphis State U., Memphis, TN 38152 Patricia Binek, 941 Moore Hall, Manhattan, KS 66506 Dean Bishop, Kansas State College, Pittsburg, KS 66762 Virginia Blake, 2357 Ridgecrest, Arnold, MO 63010 Mike Blanco, 109 Curtis, U. of Missouri, Columbia, MO 65201 Lynda Bogar, U. of Missouri, St. Louis, MO 63132 George Boguslawski, U. of Kansas, Lawrence, KS 66045 Kate Borek, Washington University, St . Louis, MO 63130 Elaine Brannen, 7 E. Harrison, Iowa City, IA 5224 0 Gerald Braver, U. of Oklahoma, Norman, OK 73019 R. P. Breitenbach, 106 Tucker, U. of Missouri, Columbia, MO 65201 Winston J. Brill, U. of Wisconsin, Madison, WI 53706 Martha Bross, 206 Fine Arts, U. of Missouri, Columbia, MO 65201 Stephen T. Butzen, Southern Illinois U., Carbondale, IL 62901 Robert L. Buzard, 61 Southside Trailer Court, Columbia , MO 65201 Pat Byrne, 408 Maupin, Columbia, MO 65201 Judy Callis, Washington University, St. Louis, MO 63130 Kay Calvert, U. of Missouri, Kansas City, MO 64101 Dale Carlson, 123A McDavid, Columbia, MO 65201 James E. Carrel, 407 Tucker, U. of Missouri, Columbia, MO 65201 Hui-shong Chang, 1509 Anthony St., Columbia, MO 65201 Linda Chapman, U. of Missouri, Columbia, MO 65201 Arthur Chovnick, U. of Connecticut, Storrs, CT 06268 E. H. Coe, 210 Curtis, U. of Missouri, Columbia, MO 65201 Mary Coe, 206 Heather Lane, Columbia, MO 65201 David R. Corbin, 111 N. Stadium, Apt. 163, Co lumbia, MO 65201 Gene Cota, 411 Constitution, Emporia, KS 66801 Nancy Cota, 411 Constitution, Emporia, KS 66801 Stan Cox, 620 Lynn Avenue, Ames, IA 50010 Katherine Cramer, Washington University, St. Louis, MO 63130 Billy G. Cumbie, 411 Tucker, U. of Missouri, Columbia, MO 65201 Diane Cuppels, U. of Nebraska, Lincoln, NE 68503 Bill Curtis, Washington University, St. Louis, MO 63130 Douglas Dalrymple, U. of Missouri , St. Louis, MO 63121 Larry Dardick, 2604B Quail Drive, Columbia, MO 65201 John David, 105 Tucker, U. of Missouri, Columbia, MO 65201 Politis Demetrios, 106 Waters, U. of Missouri, Columbia, MO 65201 Rob Denell, Kansas State U., Manhattan, KS 66506 Orchid Der, Sinclair Research Farm, Columbia, MO 65201 David Deutscher, 2012 W. Ash Street, Columbia, MO 65201 R. E. Dolphin, USDA- ARS , 800 N. Providence, Columbia, MO 65201 Gregory Doyle, 21 5 Curtis, U. of Missouri, Columbia, MO 65201 Mary Kay Doyle, 1006 Rollins, Columbia, MO 65201 Edna Dudgeon, 1502 Dunklin, Cape Girardeau, MO 63701 A. Eisenstark, 105 Tucker, U. of Missouri, Columbia, MO 65201 Mrs. A. Eisenstark, 2002 Valleyview Drive, Columbia, MO 65201 Georgia C. Eizenga, 107 Curtis, U. of Missouri, Columbia, MO 65201 Mary Enama, Washington University, St. Louis, MO 63130 Melvin D. Epp, 2 Carman Acres, Manchester, MO 63011 Dave Estervig, Box 255, Hallsville, MO 65255 Moshe Feldman, Weizmann Institute, Rehovet, Israel Mrs. Moshe Feldman, Rehovet, Israel Douglas R. Fickess , Westminster College, Fulton, MO 65251 J. R. S. Fincham, U. of Edinburgh , Edinburgh, Scotland Homer C. Folks, U. of Missouri, Columbia, MO 65201 Clark Ford, 547 Hawkeye Drive, Iowa City, Iowa 52240 Robert Frederickson, 913 Curtis Ave., Co lumbia, MO 65201 Frank Fristoe, Jr., U. of Missouri, Columbia, MO 65201 Stephen FI'y, 92 00 East EF. Avenue, Richland, MI 4 9083 a. Gavazzi, Universita di Milano, 20133 Milano, Italy James E . GHlaspy, Biology Dept. , Kingsville, TX 78363 Herbert S. Goldberg, U. of Missouri, Columbia, MO 65201 Mrs . Herbert S. Goldberg, 401 llulen Drive, Columbia, MO 65201 STADLER SYMP. Vol. 9 (1977) University of Missouri, Columbia 7

Ann Gowans, 1609 Un iversity Avenue, Columbia, MO 65201 Charles Gowans, 1609 University Avenue , Coluraliia, MC 65201 De nnis Grogan , 82813 Hatch, U. of' Missouri , Columbia , HC 6J201 Mark Guetlich, 206 Fine Arts, ll. of Missouri, Columbia, MO 65201 Sheila K. Gunn, 240 Westwood, Manhattan, KS 66506 Joanna Hanks, 3150 Christian Collef:e Ave., Columbia, MO 65201 Philip D. Harriman, U. of Missouri, Kansas City, MO 64110 Philip Hartman, 27 Rainbow Trailer Court, Columbia, MO 65201 Denise Hash, U. of Kansas, Lawrence, KS 66044 Jenna Jo Hellack, 1015 E. Brooks, Apt. G, Norman, OK 73069 Wesley Henson, U. of Tennessee, Martin, TN 38238 Carleton S. Herrick, U. of Kansas, Lawrence, KS 66044 Richard Hills, 206 Fine Arts, U. of Missouri, Columbia, MO 65201 Mark Holtmeyer, 312 Curtis, U. of Missouri, Columbia, MO 65201 Dan Hough, 212 E. Lindsay, Norman, OK 73069 LaDonna Immken, 7333 Murdoch, St. Louis, MO 63119 Patricia Jackson, 1215 Laramie, Manhattan, KS 66502 Jane Jasper, P. 0 . Box 3354, Columbia, Missouri 65201 Ernest G. Jaworski, Boo N. Lindbergh, St. Louis, MO 63166 Crak Johnson, P.O. Box 325, Columbia, MO 65201 David Jones, 312 Curtis} U. of Missouri, Columbia, MO 65201 Tim Kaiser, 5415 Harvard Drive, Bartlesville, OK 74003 Georgia Anna Kang, 110 Curtis, U. of Missouri, Columbia, MO 65201 Manjit S. Kang , 110 Curtis, U. of Missouri, Columbia, MO 65201 Ruth Kavenoff, University of California, La Jolla, CA 92037 Caroline Kennedy, 306 Hitt Street, Columbia, MO 65201 Cliff Kern, DePauw University, Greencastle, IN 46135 Larry D. Kier, Boo N. Lindbergh} St. Louis, MO 63166 Gary Y. Kikudome, 405 Tucker, U. of Missouri, Columbia, MO 65201 Gordon Kimber, 220 Curtis, U. of Missouri, Columbia, MO 65201 Yvonne Kimber, 1201 Woodhill Road, Columbia, MO 65201 Marvin Kirsh, Route 7, Box 410, Columbia, MO 65201 H. L. Kittilson, U. of Tennessee, Martin, TN 38238 Owen J. Koeppe, 114A Jesse, U. of Missouri, Columbia, MO 65201 Joseph J. Kotek, 317 N. Campus Court, Manhattan, KS 66502 Shirley Kovacs, U. of Missouri, Columbia, MO 65201 Richard Kozloff, 902 Rogers, Columbia, MO 65201 Barbara Kuyper, 510 High Street, Columbia, MO 65201 Les Lane, U. of Nebraska, Lincoln, NE 68503 Peggy Larson, Route 4, Columbia, MO 65201 Russell L. Larson, 304 Curtis, U. of Missouri, Columbia, MO 65201 Mark Latimore, Jr., lOB University Terrace} Columbia, MO 65201 H. Michael LeFever, Emporia State College, Emporia, KS 66801 Ken Leto, 108 Tucker, U. of Missouri, Columbia, MO 65201 Robin Leto, 913 Broadhead, Columbia, MO 65201 Charles Lobeck, Route 4, Columbia, MO 65201 William Q . Loegering, 106 Curtis, U. of Missouri, Columbia, MO 65201 Albert E. Longley, 2304 Mission Court, Columbia, MO 65201 John H. Longwell, 101 Dundee Drive, Columbia, MO 65201 Lorna Longwell, 101 Dundee Drive, Columbia, MO 65201 Betty Lund, Kearney, Nebraska 68847 Douglas Lund, Kearney State College, Kearney, NE 6881.J? Robert C. Malin, 410 Ripley , Columbia, MO 65201 Tom Malritz, 44~ Lee, Otsego, MI 49078 Thomas R. Manney, Kansas State U., Manhattan, KS 66506 Sandra Martin, 2401 West Broadway, Columbia, MO 65201 Stefan Martyniuk, Mumford, U. of Missouri, Colum~ia , MO 65201 Connie Masters, 56 Sunset Trailer Park, Columbia, MO 65201 Torn McClain, 4309A Mesa Drive, Columbia, MO 65201 Sheila McCormick, 210 Curtis, U. of Missouri, Columbia, MO 65201 Jim McDaniel, 213 West 21st, Pittsburg, KS 66762 Mary Ellen McGinnis, 11911 Bennington Ave., Grandview, MO 64 030 H. A. McQuade, N- 217 Med. , U. of Missouri, Columbia, MO 65201 James H. Meade, Kansas State U., Manhattan, KS 66506 Steven Meyers, 215 Waters, U. of Missouri, Columbia, MO 65201 Don Middendorf, 1100 Coats, Columbia, MO 65201 Donald Miles, U. of Missouri, Columbia, MO 65201 Judith Miles, U. of Missouri} Columbia, MO 65201 Judy Miller, U. of Missouri, St . Louis, MO 63121 Aly H. Mohamed, U. of Missouri, Kansas City, MO 61.JllO Ahmed Mahir M. Mokhtar, U. of Missouri, Columbia, MO 65201 Marion D. Murray, 2106 Southwood Drive, Columbia, MO 65201 Ahmad Bakri Mutalib, 5E U. Terrace, Columbia , MO 65201 Oval Myers, Jr., Southern Illinois U., Carbondale, IL 62901 c. J. Nelson, 16 Waters, U. of Missouri, Columbia, MO 65201 M. G. Neuffer, 202 Curtis , U. of Missouri , Columbia, MO 65201 Peter Newman, 312 Tucker, U. of Missouri , Columbia , MO 65201 B. Tracy Nixon, 4407D Bellview Drive} Columbia , MO 65201 Timothy P. O'Neill , 5406 Clark Lane, Columbia , MO 65201 Jacqueline Marie Pal , 6817 127th Terrace, Grandview , MO 64030 Lee Parks , U. of Missouri , St . Louis , MO 63121 Peter Pauw , 305 McNab, Columbia , MO 65201 8 STADLER SYMP. 9 (1977) University of Missouri, Columbia

Wayne Pedersen, U. of Nebraska, Lincoln, NE 68583 r.ary R. Petersen, 10 Homestead Apts., Columbia, MO 65201 Lo Nyok Piang, 210 Waters, u. of Missouri, Columbia MO 65201 Kathy Pinkerton, 31.tll 9 A Pa., St. Louis, MO 63118 ' Thad Pittenger, 760 Midland, Manhattan, KS 66502 J. M. Poehlman, 201 Waters, U. of Missouri, Columbia, MO 65201 Mrs. J. M. Poehlman, 1819 Ridgemont, Columbia, MO 65201 Balappa Pugashetti, 26 Mumford, U. of Missouri, Columbia, MO 65201 Carole Purcell, 210 Waug~ Street, Columbia, MO 65201 William Rafaill, Berea College CPO 1730, Berea, KY 4040-4 Ep-And Shiekh Raghad, 306 Hitt Street, Columbia, MO 65201 Douglas Randall, 105 Schweitzer, U. of Missouri, Columbia, MO 65201 Barbara Rapp, 105 Schweitzer, U. of Missouri, Columbia, MO 65201 G. P. Redei, 117 Curtis, U. of Missouri, Columbia, MO 65201 Magdi Redei, 1808 University Avenue, Columbia, MO 65201 Mari Redei, 1808 University Avenue, Columbia, MO 65201 Jack Ricketts, 3820B Juniper Court, Columbia, MO 65201 Donald Riddle, 106 Tucker, U. of Missouri, Columbia, MO 65201 Michael Riley, 1603 Harper, Lawrence, KS 66044 R. P. Robles, 304 Curtis, U. of Missouri, Columbia, MO 65201 Dan Rodgers, 112E University Village, Ames, IA 50010 Charles Rodi, 613 N. 8th, Columbia, MO 65201 Shelley Ross, 206 Fine Arts, U. of Missouri, Columbia, MO 65201 E. C. A. Runge, 135 Mumford, U. of Missouri, Columbia, MO 65201 Pat Runge, 911 Canterbury Drive, Columbia, MO 65201 Brad Schaefer, U. of Oklahoma, Norman, OK 73026 David Schlessinger, 7 4 7 5 Teasdale, St. Louis, MO 63130 Jane M. Scott, 245 N. Hyland, Ames, IA 50010 E. R. Sears, 108 Curtis, U. of Missouri, Columbia, MO 65201 Lottie M. Sears, 108 Curtis, U. of Missouri, Columbia, MO 65201 Dale S~chler, 203 Waters, U. of Missouri, Columbia, MO 65201 0. P. Sehgal, 100 Waters, U. of Missouri, Columbia, MO 65201 Joe Shea, 821 E. Walnut, Apt. 209, Columbia, MO 65201 William F. Sheridan, U. of North Dakota, Grand Forks, ND 58202 Louis Sherman, 312 Tucker, U. of Missouri, Columbia, MO 65201 P. Simmons, 327B Dockery-Folk, Columbia, MO 65201 Ellen Simpson, Washington University, St. Louis, MO 63130 Jim Slater, Neosho, MO 64850 Jan Sloan, 331 N. 17th Street, Manhattan, KS 66502 George P. Smith, 3 Tucker, U. of Missouri, Columbia, MO 65201 Jolynn Smith, Southern Illinois U., Carbondale, IL 62901 Macky Smith, Washington University, St. Louis, MO 63130 Leonard A. Sonnenschein, U. of Missouri, St. Louis, MO 63121 Probodh Srivastava, M646 Med., U. of Missouri, Columbia, MO 65201 Gary Stein, U. of Florida, Gainesville, FL 32610 Janet Stein, U. of Florida, Gainesville, FL 32610 A. B. Stephenson, 112 T-14, U. of Missouri, Columbia, MO 65201 Carolyn Stock, 201 College Avenue, Apt. 4, Columbia, MO 65201 Monroe Strickberger, U. of Missouri, St. Louis, MO 63132 Peggy Swanson 1 300 N. William, Columbia, MO 65201 Jeanne Symes 1 206 Fine Arts, U. of Missouri, Columbia, MO 65201 John Tabor, 2307 Anderson Avenue, Manhattan, KS 66502 James N. Thompson, U. of Oklahoma, Norman, OK 73019 Ann Tollefson, 26A Dockery-Folk, Columbia, MO 65201 Julie Tompson, 2301 Whitegate Drive, Columbia, MO 65201 James L. VanEtten, U. of Nebraska, Lincoln, NE 68583 Joe Varner, Washington University, St. Louis, MO 63130 John G. Waines, 3461 Anderson, Riverside, CA 92507 Virgin_ia Walbot, Washington University, St. Louis, MO 63130 Sandra Walker, U. of Missouri, Columbia, MO 65201 Jeanne Walters, U. of Missouri, St. Louis 1 MO 63121 Wei-Yeh Wang, U. of Iowa, Iowa City, Iowa 52242 Jeanne M. Wanner, 1014 Woodbine, Crestwood, MO 63126 Jeffry E. Warner, 106 Curtis, U. of Missouri, Columbia 1 MO 65201 David F. Weber, Illinois State U., Normal, IL 61761 J. A. Weir, U. of Kansas, Lawrence, KS 66045 R.H. Whalen, Brookings, South Dakota 57006 s. G. Wildman, u. of California, Los Angeles, CA 90024 Larry Williams, Kansas State U. Manhattan, KS 66506 Paula D. Williams, 107 Vine Street, Fayette, MO 65248 Robert Wixom, Ml30 Med., U. of Missouri, Columbia, MO 65201 Thomas M. Wolf, 2413 S.E. Alexander, Topeka, KS 66605 Donald C. Wolff, 2301 Whitegate Drive, Columbia, MO 65201 James H. Wyche, Ml29 Med., U. of Missouri, Columbia, MO 65201 A. F. Yanders, 210 Jesse, U. of Missouri, Columbia, MO 65201 Alan Yungbluth, 1555 Chestnut, Bowling Green, KY 42101 Allan Zacher, 300 Wilkes Blvd., Columbia, MO 65201 Mohamad Idris Zainal-Abidin, 70Jr' U. Village, Columbia, MO 65201 F. J. Zeller, U. of Missouri, Columbia, MO 65201 Mrs. F. J. Zeller, Columbia, MO 65201 Marcus Zuber, 109 Curtis, U. of Missouri, Columbia, MO 65201 Mrs. Marcus Zuber, 2211 Bushnell, Columbia> MO 65201 CUMULATIVE CONTENTS OF THE PROCEEDINGS 215 VOLUMES 1 and 2 •1971• 176 pages ($6.00) G. P. REDEI: A Portrait of L. J. Stadler 1896-1954 CURT STERN: From Crossing-Over to Developmental Genetics C. C. LINDEGREN: Biology and Biochemistry: Thesis and Antithesis T. S. PAINTER Chromosomes and Genes Viewed from a Perspective of Fifty Years Research A.H. DOERMANN: Bacteriophage T4, the Present Concept of the Gene A. H. STURTEVANT: On the Choice of Material for Genetical Studies RUTH SAGER and ZENTA RAMANIS: Formal Genetic Analysis of Organelle Genetic Systems LYNN MARGULIS: Cytoplasmic Genes - Our Precambrian Legacy S. FOGEL, D. D. HURST and R. K. MORTIMER: Gene Conversion in Un selected Tetrads from Multipoint Crosses G. W. BEADLE: Genes, Intelligence and Education W. J. Peacock: Cytogenetic Aspects of the Mechanism of Recom bination in Higher Organisms C. M. RICK: Some Cytogenetic Features of the Genome in Diploid Plant Species. VOLUME 3 •1971• 116 pages ($4.00) R. W. ALLARD and A. L. KAHLER: Allozyme Polymorphisms in Plant Populations DAVID SCHLESSINGER: Repertoire of Genetic Control of Gene Ex pression in Procaryotes ALLAN R. GOLDBERG and JERARD HURWITZ: The Catalytic Role of rho in Termination During In Vitro DNA-Dependent RNA Synthesis HAMPTON L. CARSON: Speciation and the Founder Principle TIBOR RAJHATHY: The Alloploid Model in Avena JEROME A. SCHIFF: The Informational and Nutritional Requirements of Cellular Organelles VOLUME 4 136 pages ($4.00) HERMAN W. LEWIS: Trends in Genetics Research - Prospects for Development E. R. SEARS: Chromosome Engineering in Wheat ROBERT P. WAGNER: Evolution and Genetic Significance of Mitochondria STEPHEN H. HOWELL: The Biochemistry of Meiosis and Genetic Recom- bination G. F. SPRAGUE: The Genetics of Corn Breeding LEON S. DURE III and WILLIAM C. MERRICK: The Role of tRNA in Development SHELDON C. REED and V. ELVING ANDERSON: Genetics of Psychoses CHARLES F. MULLETT: Seven (or Twenty-Seven) Against Obscurity or Still Further Observations on Tittlebats 216 STADLER SYMP. Vol. 9 (1977) University of Missouri, Columbia

VOLUME 5 •1973• 188 pages ($4.00) M. M. RHOADES : A Portrait of E. G. Anderson 1891-1973 ELOF A. CARLSON: Eugenics Revisited: The Case for Germinal Choice H. ROMAN: Studies of Recombination in Yeast A. EISENSTARK: Tryptophan Photoproduct as a Genetic Probe: Effects on Bacteria R. P. LEVINE: Membranes and Mutations in Chlamydomonas reinhardi LEE HOOD: The Genetics, Evolution and Expression of Antibody Molecules R. D. HOTCHKISS: Genetic Unity and Biochemical Diversity in Genetic Recombination Mechanisms A. TOMASZ: DNA Uptake by Bacteria and Eucaryotic Cells R. H. HODGES: Judges, Genes and Man VOLUME 6 •1974• 168 pages ($4.50) G. UNGAR: Molecular Coding of Information in the Nervous System 0. W. MCBRIDE: Metaphase Chromosome Uptake by Mammalian Cells and Expression of the Genes Transferred T. T. PUCK: The Genetics of Somatic Mammalian Cells R. H. DAVIS: Metabolic Organization in Neurospora P. S. CARLSON and T. B. RICE: Developmental Genetics and Crop Yield B. A. HAMKALO, 0. L. MILLER, JR. and A. H. BAKKEN: Electronmicro- scopic Studies of Active Genes C. S. GOWANS: Genetics and Art G. P. REDEI, G. ACEDO and G. GAVAZZI: Flower Differentiation in Arabidopsis VOLUME 7 •1975• 168 pages ($5.00) ERWIN CHARGAFF: A Few Remarks on the Impact of Biochemistry on Genetics ROBERT B. HELLING: Eukaryotic Genes in Prokaryotic Cells OLUF L. GAMBORG: Advances in Somatic Cell Hybridization in Higher Plants RICHARD B. FLAVELL and DEREK B. SMITH: Genome Organization in Higher Plants NOBORU SUEOKA: Genetic Transformation as a Tool in the Studies of DNA Replication and Recombination GEORGE B. JOHNSON: Enzyme Polymorphism and Adaptation ALLAN C. WILSON: Evolutionary Importance of Gene Regulation C. DONALD MILES: Genetic Analysis of Photosynthesis DEANE. METTER: Natural Selection and Adaptive Resemblance VOLUME 8 182 pages ($5.00) DREW SCHWARTZ: Regulation of the Alcohol Dehydrogenase Genes In Maize JOHN W. DRAKE: Mutagenic Mechanisms in Bacteriophage T4 ARNOLD L. DEMAIN: Genetic Regulation of Fermentation Organisms STADLER SYMP, Vol. 9 (1977) University of Missouri, Columbia•217

0. P. SEHGAL and C.H. HSU: RNA:Protein and Protein:Protein Inter actions in the Virions of Southern Bean Mosaic Virus JAMES E. CARREL: Aphrodisiacs and Anaphrodisiacs: Better Loving Through Chemistry ALFRED R. LOEBLICH, III: Dinoflagellate Genetics and DNA Char- acterization DAVID APIRION: Genetic Approaches to the Study of Ribosomes DAVIDE. PETTIJOHN: DNA Packaging in Isolated Bacterial Nucleoids ANTHONY CERAMI: The Development of New Drugs for Genetic Diseases VOLUME 9 •1977• 218 pages ($5.00) JAMES W. ALLEN, CHARLES F. SHULER, and SAMUEL A. LATT: Extension of BrdU-Dye Analysis of DNA Replication and Sister Chromatid Exchange Formation to In Vivo Systems G. GAVAZZI: The Genetic Complexity of the R Locus in Maize JAMES N. THOMPSON, JR.: Analysis of Gene Number and Development in Polygenic Systems HIROFUMI UCHIMIYA, KEVIN CHEN and S. G. WILDMAN: Polypeptide Composition of Fraction I Protein as an Aid in the Study of Plant Evolution DONALD L. RIDDLE: A Genetic Pathway for Dauer Larva Formation in Caenorhabditis elegans WINSTON J. BRILL: Genetics of Nitrogen Fixation RUTH KAVENOFF and BRIAN C. BOWEN: On the Organization of DNA in Isolated Bacterial Chromosomes J. R. S. FINCHAM: A Gene-Enzyme Relationship in Neurospora GARY STEIN, JANET STEIN, LEWIS KLEINSMITH, WILLIAM PARK, JUDITH THOMSON, ROBERT JANSING, ELIZABETH SHEPHARD and SIEGFRIED DETKE: Chromatin as a Model System for Studying the Regula tion of Histone Gene Expression in Mammalian Cells MOSHE FELDMAN: Historical Aspects and Significance of the Discov ery of Wild Wheats

Copies can be ordered from 117 Curtis Hall,University of Missouri, Columbia, Missouri 65201. Each order must in clude an additional 50¢ for postage and handling. Missouri residents are re quired to pay 4 % sales tax. Make checks payable to the Stadler Genetics Symposia. 218 STADLER SYMP . Vo l . 9 (1977) University of Missouri, Columbia

Dr. Ruth Kavenoff makes a hard effort to explain the super coiled structure of the chromosome (shown on her T- shirt) .

DUE RETURNED H'!IERBRANCH LOAN JAN · 8 1982 DEC 1 4 1QR1

ti~ 1 c: •c ~

OCT O 5 '84 '.

fEE:, ITR '; '~, b J.: ~ 'S:..• '

Form 104A

ELLUNIVERSITY Of MISSOURI - COLUMBIA I 0H431 .S692 (1977) v 9

Il lllll lllllll lll llll llllll lllll lllll lllll lllll lllll lllll 111111111111111111 010-009723409

OH 431 .S692 9 L05B23 . .