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T Double Helix Published by the National Foundation for Infectious Diseases | Vol. 37, No. 2 | June 2012

15th Annual Conference Highlights

he Fifteenth Annual Conference on ents-Mann Memorial Lecture in Vaccine Vaccine Research (ACVR), sponsored Sciences, “Introduction of an Affordable Group Tby the National Foundation for A Meningococcal Conjugate Vaccine in the Infectious Diseases (NFID), was held on African Belt.” May 7-9, 2012 at the Hyatt Regency Inner NFID’s Charles Mérieux Award was Harbor Hotel in , MD. presented to Arnold S. Monto, MD, the The three-day conference, devoted to Thomas Francis, Jr. Collegiate Professor of and related technologies for Epidemiology at the University of Michigan disease prevention and treatment, focused School of Public Health. This award is pre- on basic science and clinical research in sented to an individual who demonstrates a Dr. Arnold S. Monto receives the 2012 Charles Mérieux both human and veterinary medicine. The commitment to science-based medicine and Award from NFID Medical Director, Dr. Susan J. Rehm. ACVR is the premier venue for cutting- research in infectious diseases, shows excel- edge presentations and networking for lence in clinical and research activities, and ics Evaluation and Research in Bethesda, scientific collaboration in vaccine research. has an unsurpassed dedication to improving MD. The Maurice R. Hilleman, Early Stage public health. The Charles Merieux Award Career Investigator Award is supported by is supported by a grant from sanofi pasteur. unrestricted educational grant from Merck The ACVR also included the presentation & Co, Inc. of the Robert Austrian Memorial Lecture Once again, NFID sponsored an interna- by Thomas M. File, Jr., MD, professor, tional travel grants program. This activity internal medicine, master teacher and chair supported the travel and participation of 10 of the infectious disease section, Northeast researchers from developing countries with Ohio Medical University. Dr. File is NFID’s limited resources. The travel grant program newly elected president. provides an annual forum for discussion of pressing global vaccinology issues. Dr Samuel L. Katz (left) and Dr. Stanley A. Plotkin attend The lecture, underwritten by a grant the 15th Annual Conference on Vaccine Research from Merck & Co, Inc., is named in honor of the late Dr. Robert Austrian, former (VACCINE CONFERENCE, continued on page 2) The keynote address was delivered by chair of medical research at the University Stanley A. Plotkin, MD, emeritus professor of Pennsylvania, who developed the first of pediatrics, University of Pennsylvania. multivalent vaccine against pneumococcus IN THIS ISSUE In his presentation, “Vaccine Discovery – A bacteria. Varied Process,” Dr. Plotkin outlined how vaccines are actually developed by examining In its sixth year, the Maurice R. Hilleman past and future strategies. Early-Stage Career Investigator Award recognizes promising scientists who are 15th Annual Conference on Dr. Plotkin stated, “new approaches beginning their careers in vaccinology. Vaccine Research Highlights...... 1 to vaccine development are necessary. The 2012 award was presented to Olga Although trial and error will continue to be Clinical Vaccinology A. Lihoradova, PhD, University of Texas Course Scheduled ...... 3 a major way forward, it is likely that single Medical Branch, Galveston, TX for her antigens will not be sufficient for optimal presentation “Characterization of Rift Valley Campaign for Adult protection and indeed that more than one Fever MP-1 Vaccine Encoding the NSs Gene Immunization ...... 3 immune response will have to be induced.” Derived from Other Phleboviruses.” NFID Board Election ...... 4 F. Marc LaForce, MD, director of the The two semifinalists were Mohammad Meningitis Vaccine Project at the Program Khan, MBBS, MSc, PhD of the Interna- Calendar of Events...... 4 for Appropriate Technology in Health tional Vaccine Institute in Seoul, Korea and (PATH), presented the Mary Lou Clem- Jian Wu, PhD from the Center for Biolog- HE 2 Vol. 37, No.2 | June 2012 T Double Helix

(ANNUAL CONFERENCE, from page 1) HE

T Double Helix The National Foundation for Infectious Diseases (NFID) is a non-profit, tax-exempt 501(c)(3) public foundation established in 1973 to educate the public and health care professionals about the causes, treatment, and prevention of infectious diseases.

BOARD OF DIRECTORS

President...... Thomas M. File, Jr., MD President-Elect...... Patrick Joseph, MD Vice President...... Walter A. Orenstein, MD Treasurer...... Georges Peter, MD Secretary...... Patricia N. Whitley-Williams, MD Dr. Olga A. Lihoradova receives the 2012 Hillemen Award from Dr. Bruce Weniger, Annual Conference on Vaccine Research Conference Co-Chair. Carol J. Baker, MD Joseph Anthony Bocchini, Jr., MD Other invited and submitted presentations highlighted advances in vaccine discovery, Richard J. Duma, MD Kathryn M. Edwards, MD rotavirus vaccines, vaccines for enteric diseases, food safety vaccines, vaccine adjuvants, George M. Eliopoulos, MD and vaccine candidates. Poster presentations covered preclinical and clinical studies, Jeffrey P. Engel, MD immunization policies and programs, immunologic science, the impact of vaccines on Eliot W. Godofsky, MD disease burden, vaccine safety, vaccine adjuvants, and scientific assessment of vaccine Michael D. Hogue, PharmD adverse events. Marguerite McMillan Jackson, PhD, RN Kathryn Brawley Kirkland, MD The Annual Conference on Vaccine Financial support for the conference was William J. Ledger, MD Research is sponsored by NFID in provided through unrestricted educational Donna Mazyck, RN, MS collaboration with: grants from: Gary J. Nabel, MD Peter L. Nara, M Sc, DVM, PhD • American Pharmacists Association • Aeras Global TB Vaccine Foundation Ronald Lee Nichols, MD, FACS Gary A. Noskin, MD • American Veterinary • BD Diagnostics George A. Pankey, MD, MACP Medical Association • Crucell Holland B.V. Kevin M. Rooney • Center for Vaccine Development, • CSL Biotherapies William Schaffner, MD University of Maryland Eric Schultz • Dynavax Technologies Thomas G. Slama, MD, FACP • Centers for Disease Control and Patricia Stinchfield, RN, MS Prevention (CDC) • Epivax, Inc. H. Keipp B. Talbot, MD, MPH • Genvec Vincent H. Tam, PharmD, BCPS • Edward Jenner Society Cynthia G. Whitney, MD, MPH • Emory Vaccine Center • Inovio Pharmaceuticals, Inc. Lucy E. Wilson, MD • FDA Center for Biologics • LigoCyte Pharmaceuticals EXECUTIVE DIRECTOR Evaluation and Research • Liquidia Technologies Leonard Novick • Fondation Mérieux • MedImmune, Inc. MEDICAL DIRECTOR • International Alliance for Susan J. Rehm, MD • Merck & Co., Inc. Biological Standardization • Novartis Vaccines EDITORS • National Institute of Allergy • Novavax, Inc. Leonard Novick and Infectious Diseases/NIH Susan J. Rehm, MD • Sanofi Pasteur • One Health Initiative ASSOCIATE EDITOR • US Food and Drug Administration Sharon Cooper-Kerr • Sabin Vaccine Institute • Society of Infectious Diseases Pharmacists Published by The Sixteenth Annual Conference on National Foundation for Infectious Diseases • USDA Agricultural Vaccine Research will be held April 22 - 24, 4733 Bethesda Avenue | Suite 750 Research Service 2013, at the Hyatt Regency Inner Harbor Hotel Bethesda, MD 20814–5228 in Baltimore, MD. A call for abstracts will be • University of Texas Telephone: 301.656.0003 | Fax: 301.907.0878 available November 2012 for the 16th Annual E-mail: [email protected] Web Site: www.nfid.org Sealy Center for Vaccine Conference. Please visit www.nfid.org for more ISSN: 1064-1815 Development information in the fall. HE 3 Vol. 37, No.2 | June 2012 T Double Helix Clinical Vaccinology Course Scheduled

The National Foundation for Infectious Diseases (NFID) announces the dates for its The Clinical Vaccinology Course has been Clinical Vaccinology Course. The course, co-sponsored by NFID, Emory Department planned and implemented in accordance of Medicine, Division of Infectious Diseases and the Emory Vaccine Center will be held with the Essential Areas and policies of the November 2 - 4, 2012, at the Hyatt Regency Miami in Miami, FL. The course will also be Accreditation Council for Continuing Medi- held in Chicago, March 9 - 10, 2013 at the Hyatt Regency Chicago in Chicago, IL. cal Education (ACCME). NFID designates this educational activity for a maximum of The course is specifically designed for primary care physicians, nurses, nurse TM practitioners, pharmacists, physician assistants, public health specialists, infectious 19 AMA PRA Category 1 Credit(s) . NFID is disease specialists, and other healthcare professionals involved with clinical aspects an approved provider of continuing nursing of vaccinology. education by the Maryland Nurses Associa- tion, an accredited approver by the Ameri- can Nurses Credentialing Center’s Com- . The Clinical Vaccinology Course will feature sessions addressing: mission on Accreditation. This educational • How Vaccines Work activity has been approved for 19 contact • The Advisory Committee on Immunization Practices hours. The course will also offer pharmacy • Childhood and Adolescent Immunization education credits through PharmCon which • Clinical Cases in Vaccinology is accredited by the Accreditation Council • Adult and Adolescent Immunization Challenges for Pharmacy Education as a provider for • Childhood Immunization Challenges continuing pharmacy education. • Special Vaccine Issues Online registration is now open for the • Special Populations November course. The cost to attend is $590 • Communication Issues prior to September 17, 2012 and $690 after Keynote presentations include: this date. Discounted course registration will • An Overview of Vaccinology—Walter A. Orenstein, MD be offered to medical students, doctoral stu- Emory Vaccine Center dents, residents, fellows, physician assistants, • Pneumococcal Vaccines Across the Lifespan—Matthew R. Moore, MD, MPH nurse practitioners, and NFID supporting Centers for Disease Control and Prevention members. Additional information about the • Influenza Vaccine: Strains, Supply, and Schedule: Give the Right Dose at the Right Time— course, including full course agenda and fac- Wendy A. Keitel, MD, Baylor College of Medicine ulty listing, is available on the NFID website, www.nfid.org. The course will feature Meet the Experts breakfast sessions to allow attendees an opportunity to network with seasoned colleagues specializing in vaccinology.

National Adult Immunization Campaign Launched The National Foundation for Infec- www.adultimmunization.org. According to Deborah J. Wexler, MD, campaign tious Diseases (NFID), in partnership with Campaign Chair and adult vaccine expert, advisory board member and executive leading medical experts and national health William Schaffner, MD, “Vaccine-prevent- director of the Immunization Action organizations, launched its Campaign for able diseases are taking a heavy toll on the Coalition added, “The impact of disease Adult Immunization at the inaugural country’s health, unnecessarily draining spreads further than people think: unvac- National Adult Immunization Summit in medical and financial resources at a time cinated adults leave themselves, their loved Atlanta, GA. The Campaign is a multi- when the nation should be focused on ones, and their communities vulnerable to disciplinary, unified national effort to bring curbing costs through prevention. Immu- contracting often deadly diseases.” all stakeholder groups interested in adult nizing adults is an easy way to save tens of In addition to the clear medical impact immunization under one advocacy umbrella thousands of lives and billions of dollars.” of infectious diseases on the country, to support adult immunization issues. The Campaign for Adult Immunization these preventable diseases also have huge The Campaign for Adult Immuniza- will seek to address immunization barri- financial burdens for individuals and tion aims to reduce the more than 50,000 ers, such as awareness and cost issues, that society-at-large. “The cost of treating just annual vaccine-preventable deaths by the public health community has encoun- influenza and pneumococcal disease increasing awareness of, and access to, tered for years. “We know the problems,” reaches into the tens of billions of dollars recommended adult vaccines. Currently, noted Campaign advisory board member every year,” explained Litjen Tan, PhD, vaccine-preventable diseases kill more US Gregory A. Poland, MD, director of the Campaign advisory board member and adults than breast cancer, HIV/AIDS, or Mayo Vaccine Research Group. “But now director of Medicine and Public Health at motor vehicle traffic accidents. we need implementable, effective solu- the American Medical Association. Several national organizations have tions. This campaign will offer out-of-the- already signed on as Campaign partners. box thinking to deliver real increases in A complete list of partners is available at adult vaccination rates.” HE 4 Vol. 37, No.2 | June 2012 T Double Helix

New Members Elected to NFID Board of Directors

The National New Directors George A. Pankey, MD NFID Board Officers Foundation for Carol J. Baker, MD Ochsner Clinic Foundation Thomas M. File, Jr., MD Infectious Diseases Baylor College of Medicine Kevin M. Rooney President (NFID) elected new Jeffrey P. Engel, MD Beacon Consulting Group Patrick Joseph, MD members to its Board NC Dept. of Health Eric Schultz President-Elect of Directors board & Human Services QuantiaMD meeting this month. Walter A. Orenstein, MD Eliot W. Godofsky, MD H. Keipp B. Talbot, MD Vice President Bach & Godofsky, MD, PA Vanderbilt University Georges Peter, MD Michael D. Hogue, PharmD School of Medicine Treasurer McWhorter School of Pharmacy Lucy E. Wilson, MD Patricia N. Whitley-Williams, MD William J. Ledger, MD Maryland Department of Secretary Health & Mental Hygiene Weill Medical College Outgoing NFID President, of Cornell University William Schaffner, MD Gary J. Nabel, MD Vanderbilt University became Bethesda, MD NFID’s Immediate Past President.

Calendar of NFID Events and Meetings Take Me Out to the Ballgame

September 21, 2012 April 22–24, 2013 On Friday, September 21, 2012, NFID will be sponsoring a “Flu Awareness Night” at the NFID Flu Awareness Night Sixteenth Annual Conference on Vaccine Research Washington Nationals baseball game against the Milwaukee Brewers in Washington, DC. NFID Flu Awareness Night Hyatt Regency Inner Harbor Hotel During the event, the NFID public service Nationals Park in Baltimore, MD announcement “Are You That Guy?” will be Washington Nationals shown on the Jumbotron prior to the start of vs. the game, NFID staff will be at the community Milwaukee Brewers For more information about kiosk distributing flu information flyers and Visit www.nfid.org for giveaways as well as vouchers for those receiving additional information NFID sponsored events and flu vaccines at local Harris Teeter grocery stores, meetings, please contact: and a special welcome message will be displayed November 2–4, 2012 on the scoreboard between the 4th and 5th Sharon Cooper-Kerr, NFID innings. A customized online purchase page has Clinical Vaccinology Course 4733 Bethesda Avenue | Suite 750 been developed (www.nationals.com/flu) for Hyatt Regency Miami in Bethesda, MD 20814-5278 tickets available at a discounted group rate, with Miami, FL a portion of ticket sales being donated to NFID. Telephone: 301.656.0003, Ext 14 Come out and join us for this special evening! March 8–10, 2013 Fax: 301.907.0878 Clinical Vaccinology Course E-mail: [email protected] Hyatt Regency Chicago in or visit our website at Chicago, IL www.nfid.org