BCL7A Antibody Cat

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BCL7A Antibody Cat. No.: 45-325 BCL7A Antibody 45-325 Immunofluorescence analysis of 45-325 Flow cytometric analysis of paraformaldehyde paraformaldehyde fixed U2OS cells, permeabilized with fixed Daudi cells (blue line), permeabilized with 0.5% 0.15% Triton. Primary incubation 1hr (10ug/ml) followed Triton. Primary incubation 1hr (10ug/ml) followed by Alexa by Alexa Fluor 488 secondary antibody (2ug/ml), showing Fluor 488 secondary antibody (1ug/ml). IgG control: nuclear staining. Actin filaments were stained wit Unimmunized goat IgG (black line) fo Specifications HOST SPECIES: Goat SPECIES REACTIVITY: Human HOMOLOGY: Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Cow, Pig IMMUNOGEN: The immunogen for this antibody is: C-MKLEASQQNSEEM TESTED APPLICATIONS: ELISA, Flow, IF, WB October 2, 2021 1 https://www.prosci-inc.com/bcl7a-antibody-45-325.html Peptide ELISA: antibody detection limit dilution 1:4000.Western Blot:Approx 26kDa band observed in Human Lymph Node lysates (calculated MW of 25.0kDa according to NP_066273.1). Recommended concentration: 1-3ug/ml. Primary incubation 1 hour at APPLICATIONS: room temperature.Immunofluorescence: Strong expression of the protein seen in the nuclei of U2OS cells. Recommended concentration: 10ug/ml. Flow Cytometry: Flow cytometric analysis of Daudi cells. Recommended concentration: 10ug/ml. This antibody is expected to recognize both reported isoforms (NP_066273.1; SPECIFICITY: NP_001019979.1). POSITIVE CONTROL: 1) Cat. No. 1201 - HeLa Cell Lysate Properties Purified from goat serum by ammonium sulphate precipitation followed by antigen PURIFICATION: affinity chromatography using the immunizing peptide. CLONALITY: Polyclonal CONJUGATE: Unconjugated PHYSICAL STATE: Liquid Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum BUFFER: albumin. Aliquot and store at -20°C. Minimize freezing and thawing. CONCENTRATION: 500 ug/mL STORAGE CONDITIONS: Aliquot and store at -20˚C. Minimize freezing and thawing. Additional Info OFFICIAL SYMBOL: BCL7A ALTERNATE NAMES: BCL7A, BCL7, B-cell CLL/lymphoma 7A, B-cell CLL/lymphoma-7 ACCESSION NO.: NP_066273.1, NP_001019979.1 PROTEIN GI NO.: 10337613 GENE ID: 605 Background and References 1) Zani VJ, Asou N, Jadayel D, Heward JM, Shipley J, Nacheva E, Takasuki K, Catovsky D, Dyer MJ. Molecular cloning of complex chromosomal translocation REFERENCES: t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line defines a new gene (BCL7A) with homology to caldesmon. Blood 1996 Apr 15;87(8):3124-34 ANTIBODIES FOR RESEARCH USE ONLY. October 2, 2021 2 https://www.prosci-inc.com/bcl7a-antibody-45-325.html For additional information, visit ProSci's Terms & Conditions Page. October 2, 2021 3 https://www.prosci-inc.com/bcl7a-antibody-45-325.html.

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BCL7A As a Novel Prognostic Biomarker for Glioma Patients
BCL7A as a novel prognostic biomarker for glioma patients Junhui Liu ( [email protected] ) Renmin Hospital of Wuhan University: Wuhan University Renmin Hospital Lun Gao Renmin Hospital of Wuhan University: Wuhan University Renmin Hospital Baowei Ji Renmin Hospital of Wuhan University: Wuhan University Renmin Hospital Rongxin Geng Renmin Hospital of Wuhan University: Wuhan University Renmin Hospital Jing Chen Renmin Hospital of Wuhan University: Wuhan University Renmin Hospital Xiang Tao Renmin Hospital of Wuhan University: Wuhan University Renmin Hospital Qiang Cai Renmin Hospital of Wuhan University: Wuhan University Renmin Hospital Zhibiao Chen Renmin Hospital of Wuhan University: Wuhan University Renmin Hospital Research Article Keywords: BCL7 family, glioma, prognosis, immune, Temozolomide Posted Date: April 21st, 2021 DOI: https://doi.org/10.21203/rs.3.rs-390165/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Version of Record: A version of this preprint was published at Journal of Translational Medicine on August 6th, 2021. See the published version at https://doi.org/10.1186/s12967-021-03003-0. Page 1/24 Abstract Background: Glioma is the most common primary brain tumor and represents one of the most aggressive and lethal types of human cancer. BCL7 family has been found in several cancer types and could be involved in tumor progression. While the role of BCL7 family in human glioma has remained to be elucidated. Methods: Paran-embedded tumor samples were obtained to detect BCL7 expression by performing in glioma. Data (including normalized gene expression and corresponding clinical data) were obtained from Gliovis, CGGA, GEO, cBioportal and Oncomine and were used to investigate BCL7 genes expression in glioma.
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Gene Name Forward Primer Reverse Primer ACTB CTGGAACGGTGAAGGTGACA AAGGGACTTCCTGTAACAATGCA ACVRL1 ACATGAAGAAGGTGGTGTGTGTGG CGGGCAGAGGGGTTTGGGTA ADAMDEC1 GGGGCCAGACTACACTGAAACATT ACCCGTCACAAGTACTGATGCTG AHI1 GTCCAAAACTACCCCATCAAGGCT GCAGCACAGGAACGTATCACCT ANGPT2 TGGCAGCGTTGATTTTCAGAGG GCGAAACAAACTCATTTCCCAGCC ANPEP TGAAGAAGCAGGTCACACCCCT AACTCCGTTGGAGCAGGCGG APOA1 GCCGTGCTCTTCCTGACGG TGGGACACATAGTCTCTGCCGC ATXN7 CACCGCCCACTCTGGAAAAGAA GGGTGCAGGGCTTCTTGGTG B2M TGCTGTCTCCATGTTTGATGTATCT TCTCTGCTCCCCACCTCTAAGT BAG4 AGGTTCCAGGATATCCGCCTT TCGGTCCTGATTGTGGAACACT BCL2 ACAACATCGCCCTGTGGATGA CCGTACAGTTCCACAAAGGCAT BCL2L14 GCTCAGGGTCAAAGGACGTTGG TCAGCTACTCGGTTGGCAATGG BCL7A GAACCATGTCGGGCAGGTCG CCCATTTGTAGATTCGTAGGGATGTGT BIN1 TGCTGTCGTGGTGGAGACCTTC GCCGTGTAGTCGTGCTGGG BIRC3 TGCTATCCACATCAGACAGCCC TCTGAATGGTCTTCTCCAGGTTCA BIRC5 TTCTCAAGGACCACCGCATCT AGTGGATGAAGCCAGCCTCG BLK TCGGGGTCTTCACCATCAAAGC GCGCTCCAGGTTGCGGATGA BTRC CCAAATGTGTCATTACCAACATGGGC GCAGCACATAGTGATTTGGCATCC BUB3 CGGAACATGGGTTACGTGCAGC CCAAATACTCAACTGCCACTCGGC CAGE1 TCCAAAATGCACAGTCTTCTGGCT GGAGGCTCTTCAGTTTTTGCAGC CASP1 CCTGTTCCTGTGATGTGGAGGAAA GCTCTACCATCTGGCTGCTCAA CASP3 AGCGAATCAATGGACTCTGGAATATCC GTTTGCTGCATCGACATCTGTACCA CCL5 TCATTGCTACTGCCCTCTGCG ACTGCTGGGTTGGAGCACTTG CCL18 CCCTCCTTGTCCTCGTCTGCA GCACTGGGGGCTGGTTTCAG CCL26 TTCCAATACAGCCACAAGCCCC GGATGGGTACAGACTTTCTTGCCTC CCND2 TCAAGTGCGTGCAGAAGGACAT CTTCGCACTTCTGTTCCTCACA CCND3 TGGCTGCTGTGATTGCACATGA GATGGCGGGTACATGGCAAAGG CCR3 ACGCTGCTCTGCTTCCTGG TCCTCAGTTCCCCACCATCGC CCR4 AGCATCGTGCTTCCTGAGCAA GGTGTCTGCTATATCCGTGGGGT CCR7 AGACAGGGGTAGTGCGAGGC
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