biology Article Physiological and Psychological Effects of Treadmill Overtraining Implementation Yi Chung 1 , Yi-Ting Hsiao 2 and Wen-Ching Huang 2,3,* 1 College of Human Development and Health, National Taipei University of Nursing and Health Sciences, Taipei 11219, Taiwan;
[email protected] 2 Department of Exercise and Health Science, National Taipei University of Nursing and Health Sciences, Taipei 11219, Taiwan;
[email protected] 3 Graduate Institute of Metabolism and Obesity Sciences, Taipei Medical University, Taipei 11031, Taiwan * Correspondence:
[email protected]; Tel.: +886-2-2822-7101 (ext. 7721) Simple Summary: Overtraining occurs when an imbalance between training stress and recovery ex- ists, and it is prevalent in athletes, soldiers, physical education, and health education undergraduates as well as a number of female and male adolescents. Despite a broad body of evidence concerning physiological and psychological correlates of this syndrome, the pathomechanisms of overtraining are still poorly understood. This illustrates the need to establish animal models of this disorder. This article outlines and discusses physiological and psychological effects of the current established overtraining model, based on an eight-week exhaustive treadmill exercise that reveals the involve- ment of imbalanced energy expenditure, exacerbated inflammatory response, increased intestinal permeability, and anxiety status in the development and onset of overtraining. This study highlights the maladaptation of overtraining and provides an animal model to determine the effectiveness of possible strategies, including nutrition and monitoring, for treatment and prevention of overtraining syndromes in future studies. Citation: Chung, Y.; Hsiao, Y.-T.; Abstract: Overtraining in athletes usually causes profound and lasting deleterious effects on the Huang, W.-C.