Chemistry (CHEM) 1
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Course CHEM 3341, Inorganic Chemistry Professor Dr. Sheel Dodani Term Fall 2016 Meetings MWF 10:00-10:50 AM, MC 2.410
Course CHEM 3341, Inorganic Chemistry Professor Dr. Sheel Dodani Term Fall 2016 Meetings MWF 10:00-10:50 AM, MC 2.410 Professor’s Contact Information Office Phone 972-883-7283 Other Phone N/A Office Location Bioengineering Science Building (BSB) Email Address [email protected] Office Hours Wednesdays 11:30 AM – 12:30 PM, Thursdays 4 PM – 5 PM BSB 11.302 Other Information Please contact me for appointments outside of office hours General Course Information Pre-requisites, Co- requisites, & other Chem 2323 and Chem 2325 restrictions Survey of inorganic chemistry with emphasis on the modern concepts and theories of inorganic chemistry including electronic and geometric Course Description structure of inorganic compounds. Topics address contemporary physical and descriptive inorganic chemistry. Objectives The goal of this course is to provide students with a thorough foundation in atomic structure, periodicity, bonding and symmetry with subsequent extension of these basic principles to acid/base, solid state and coordination chemistry. Students will develop an understanding of the elements and the ability to predict the structures, certain properties and reactivities of a range of representative ionic and covalent compounds. Learning Expected Learning Outcomes Outcomes Upon successful completion of this course, students will therefore: 1. Be able to explain atomic structure and bonding using currently accepted theories. 2. Be able to use group theory to describe molecular orbital diagrams and molecular properties. 3. Be able to integrate knowledge of atomic structure with the structure and properties of ionic and molecular compounds. 4. Be able to explain the history, bonding and properties of representative main group elements, coordination and organometallic compounds Inorganic Chemistry, 5th Edition Required Texts & by Gary L. -
General Inorganic Chemistry
General Inorganic Chemistry Pre DP Chemistry Period 1 • Teacher: Annika Nyberg • [email protected] • Urgent messages via Wilma! Klicka här för att ändra format på underrubrik i bakgrunden • Course book: • CliffsNotes: Chemistry Quick Review http://www.chem1.com/acad/webtext/virtualtextbook.html Content • Introduction • The Structure of Matter (Chapter 1) • The Atom (Chapter 2 and 3) • Chemical bonding (Chapter 5) • The Mole (Chapter 2) • Solutions (Chapter 9) • Acids and bases (Chapter 10) • Quiz • Revision • EXAM 9.00-11.45 Assessment Exam: 80 % Quiz: 20% + practical work, activity and absences 1. Chemistry: a Science for the twenty-first century ● Chemistry has ancient roots, but is now a modern and active, evolving science. ● Chemistry is often called the central science, because a basic knowledge of chemistry is essential for students in biology, physics, geology and many other subjects. https://www.youtube.com/watch?v=tTlnrhiadnI ● Chemical research and development has provided us with new substances with specific properties. These substances have improved the quality of our lives. Health and medicine vaccines sanitation systems antibiotics anesthesia and all other drugs Energy new alternative energy sources (e.g. solar energy to electric energy, nuclear fission) electric cars with long lasting batteries Environment greenhouse gases acid rain and smog Materials and Technology ● polymers (rubber and nylon), ceramics (cookware), liquid crystals (electronic displays), adhesives (Post-It notes), coatings (latex-paint), silicon chips (computers) Food and Agriculture substances for biotechnology ● The purpose of this course is to make you understand how chemists see the world. ● In other words, if you see one thing (in the macroscopic world) you think another (visualize the particles and events in the microscopic world). -
Phytochemistry and Pharmacogenomics of Natural Products Derived from Traditional Chinese Medicine and Chinese Materia Medica with Activity Against Tumor Cells
152 Phytochemistry and pharmacogenomics of natural products derived from traditional chinese medicine and chinese materia medica with activity against tumor cells Thomas Efferth,1 Stefan Kahl,2,3,6 Kerstin Paulus,4 Introduction 2 5 3 Michael Adams, Rolf Rauh, Herbert Boechzelt, Cancer is responsible for 12% of the world’s mortality and Xiaojiang Hao,6 Bernd Kaina,5 and Rudolf Bauer2 the second-leading cause of death in the Western world. 1 Limited chances for cure by chemotherapy are a major German Cancer Research Centre, Pharmaceutical Biology, contributing factor to this situation. Despite much progress Heidelberg, Germany; 2Institute of Pharmaceutical Sciences, University of Graz; 3Joanneum Research, Graz, Austria; 4Institute in recent years,a key problem in tumor therapy with of Pharmaceutical Biology, University of Du¨sseldorf, Du¨sseldorf, established cytostatic compounds is the development of Germany; 5Institute of Toxicology, University of Mainz, Mainz, 6 drug resistance and threatening side effects. Most estab- Germany; and State Key Laboratory of Phytochemistry and Plant lished drugs suffer from insufficient specificity toward Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China tumor cells. Hence,the identification of improved anti- tumor drugs is urgently needed. Several approaches have been delineated to search for Abstract novel antitumor compounds. Combinatorial chemistry,a The cure from cancer is still not a reality for all patients, technology conceived about 20 years ago,was envisaged as which is mainly due to the limitations of chemotherapy a promising strategy to this demand. The expected surge in (e.g., drug resistance and toxicity). Apart from the high- productivity,however,has hardly materialized (1). -
Chemistry ‐ Student Learning Outcomes CHEM 100 Introduction to Chemistry 1.Analyze Chemical Reactions and Chemical Problems Through Stoichiometry
Chemistry ‐ Student Learning Outcomes CHEM 100 Introduction To Chemistry 1.analyze chemical reactions and chemical problems through stoichiometry. (ILO2) 2. predict properties of matter using atomic theory. (ILO2) 3. use the periodic table properly to determine trends in elements (atomic size, number of valence electrons, metallic character, electronegativity, etc.). (ILO2, ILO4) 4. perform chemical experiments in a safe, accurate, and scientific manner, using proper glasswares, graphs, and spreadsheets. (ILO2, ILO4) CHEM 160 Introduction to General, 1. calculate drug dosage using English and Metric unit interconversions and dimensional Organic & Biological analysis. (ILO4) Chemistry 2. identify different classes of organic compounds. (ILO2) 3. identify different functional groups in organic compounds. (ILO2) 4. write a research paper on biochemical disorders. (ILO4) 5. discuss the geographical/ethnic distribution of biochemical disorders. (ILO5) CHEM 200 General Inorganic Chemistry I 1. perform dimensional analysis calculations as they relate to problems involving percent composition and density. (ISLO2) 2. write chemical formulas, and name inorganic compounds. (ISLO2) 3. relate chemical equations and stoichiometry as they apply to the mole concept. (ISLO2) 4. identify the basic types of chemical reactions including precipitation, neutralization, and oxidation‐reduction. (ISLO4) 5. knowledge of atomic structure and quantum mechanics and apply these concepts to the study of periodic properties of the elements. (ISLO4) CHEM 202 General Inorganic Chemistry 1. examine and develop concepts of covalent bonding, orbital hybridization and II molecular orbital theory. (ISLO4) 2. identify and perform organic addition and elimination reactions. (ISLO2) 3. compare and analyze Thermodynamics properties and differentiate between spontaneity and maximum useful work heat and Free energy. (ISLO2) 4. -
Virtual Screening for the Discovery of Bioactive Natural Products by Judith M
Progress in Drug Research, Vol. 65 (Frank Petersen and René Amstutz, Eds.) © 2008 Birkhäuser Ver lag, Basel (Swit zer land) Virtual screening for the discovery of bioactive natural products By Judith M. Rollinger1, Hermann Stuppner1,2 and Thierry Langer2,3 1Institute of Pharmacy/Pharmacog- nosy, Leopold-Franzens University of Innsbruck, Innrain 52c, 6020 Innsbruck, Austria 2Inte:Ligand GmbH, Software Engineering and Consulting, Clemens Maria Hofbauergasse 6, 2344 Maria Enzersdorf, Austria 3Institute of Pharmacy/Pharmaceu- tical Chemistry/Computer Aided Molecular Design Group, Leopold- Franzens University of Innsbruck, Innrain 52c, 6020 Innsbruck, Austria <[email protected]> Virtual screening for the discovery of bioactive natural products Abstract In this survey the impact of the virtual screening concept is discussed in the field of drug discovery from nature. Confronted by a steadily increasing number of secondary metabolites and a growing number of molecular targets relevant in the therapy of human disorders, the huge amount of information needs to be handled. Virtual screening filtering experiments already showed great promise for dealing with large libraries of potential bioactive molecules. It can be utilized for browsing databases for molecules fitting either an established pharma- cophore model or a three dimensional (3D) structure of a macromolecular target. However, for the discovery of natural lead candidates the application of this in silico tool has so far almost been neglected. There are several reasons for that. One concerns the scarce availability of natural product (NP) 3D databases in contrast to synthetic libraries; another reason is the problematic compatibility of NPs with modern robotized high throughput screening (HTS) technologies. -
CHEM 110 Week 1 Inorganic Chemistry I Atoms, Elements, and Compounds
CHEM 110 Week 1 Inorganic Chemistry I Atoms, Elements, and Compounds Week 1 Reading Assignment Your week 1 reading assignment has been selected from chapters 3 and 5 in your textbook. As part of your reading assignment, you are expected to work the sample problems and the selected “questions and problems” at the end of your book sections. The answers to the odd numbered “questions and problems” can be found at the end of your book chapters. You should use this key to check yourself. If you are having problems arriving at the correct answer as listed in the back of your book chapter, please email me. Read section 3.1 and answer the odd numbered “questions and problems” on page 85. Read section 3.2 and answer the odd numbered “questions and problems” on page 91. Read section 3.3 and answer “questions and problems” 3.15 and 3.17 on page 94. You do not have to know the experimental details used to determine the structure of an atom. Read section 3.4 and answer the odd numbered “questions and problems” on page 97. Read about isotopes and atomic mass in section 3.5 and answer “questions and problems” 3.29 and 3.31 on page 100. Skip the part on calculating atomic mass using isotopes. Read section 3.6. Read section 3.7. Read about “Group Number and Valence Electrons” and “Electron-Dot Symbols” in section 3.8. Answer “questions and problems” 3.57 and 3.59 on page 118. Read section 5.1 and answer the odd numbered “questions and problems” on page 163 and 164. -
25Th Anniversary of Molecules—Recent Advances in Inorganic Chemistry
molecules Editorial 25th Anniversary of Molecules—Recent Advances in Inorganic Chemistry Burgert Blom 1,* , Erika Ferrari 2 , Vassilis Tangoulis 3 ,Cédric R. Mayer 4, Axel Klein 5 and Constantinos C. Stoumpos 6 1 Maastricht Science Programme, Assistant Professor of Inorganic Chemistry and Catalysis, Maastricht University, Kapoenstraat 2, P.O. Box 616, 6200 MD Maastricht, The Netherlands 2 Department of Chemical and Geological Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy; [email protected] 3 Department of Chemistry, University of Patras, 26504 Patras, Greece; [email protected] 4 Laboratoire LuMin, FRE CNRS 2036, CNRS, Université Paris-Sud, ENS Paris-Saclay, Centrale Supelec, Université Paris-Saclay, F-91405 Orsay CEDEX, France; [email protected] 5 Department für Chemie, Institut für Anorganische Chemie, Universität zu Köln, Greinstraße 6, 50939 Köln, Germany; [email protected] 6 Department of Chemistry, Northwestern University, Evanston, IL 60208, USA; [email protected] * Correspondence: [email protected] Celebrating the “25th Anniversary of Molecules” with a Special Issue dedicated to “Recent Advances in Inorganic Chemistry” strengthens the renewed role that inorganic chemistry, one of the oldest chemistry divisions, has lately earned thanks to cutting-edge perspectives and interdisciplinary applications, eventually receiving the veneration and respect which its age might require [1,2]. The last 25 years have seen staggering advances in both solid-state, molecular, catalytic Citation: Blom, B.; Ferrari, E.; Tangoulis, V.; Mayer, C.R.; Klein, A.; and bio-inorganic chemistry. Some notable highlights in molecular inorganic chemistry Stoumpos, C.C. 25th Anniversary of over the last 2.5 decades certainly must include the propensity of heavy p-block elements Molecules—Recent Advances in (those in period 3 or higher) to undergo multiple bonding with other heavy p-block Inorganic Chemistry. -
Combinatorial and High-Throughput Screening of Materials Libraries: Review of State of the Art Radislav Potyrailo*
REVIEW pubs.acs.org/acscombsci Combinatorial and High-Throughput Screening of Materials Libraries: Review of State of the Art Radislav Potyrailo* Chemistry and Chemical Engineering, GE Global Research Center, Niskayuna, New York 12309, United States Krishna Rajan Department of Materials Science and Engineering and Institute for Combinatorial Discovery, Iowa State University, Ames, Iowa 50011, United States Klaus Stoewe Universit€at des Saarlandes, Technische Chemie, Campus C4.2, 66123, Saarbruecken, Germany Ichiro Takeuchi Department of Materials Science and Engineering, University of Maryland, College Park, Maryland 20742, United States Bret Chisholm Center for Nanoscale Science and Engineering and Department of Coatings and Polymeric Materials, North Dakota State University, Fargo, North Dakota 58102, United States Hubert Lam Chemistry and Chemical Engineering, GE Global Research Center, Niskayuna, New York 12309, United States ABSTRACT: Rational materials design based on prior knowledge is attractive because it promises to avoid time-consuming synthesis and testing of numerous materials candidates. However with the increase of complexity of materials, the scientific ability for the rational materials design becomes progressively limited. As a result of this complexity, combinatorial and high-throughput (CHT) experimentation in materials science has been recognized as a new scientific approach to generate new knowledge. This review demonstrates the broad applicability of CHT experimentation technologies in discovery and optimiza- tion of new materials. We discuss general principles of CHT materials screening, followed by the detailed discussion of high-throughput materials characteriza- tion approaches, advances in data analysis/mining, and new materials develop- ments facilitated by CHT experimentation. We critically analyze results of materials development in the areas most impacted by the CHT approaches, such as catalysis, electronic and functional materials, polymer-based industrial coatings, sensing materials, and biomaterials. -
Combinatorial Chemistry: a Guide for Librarians
City University of New York (CUNY) CUNY Academic Works Publications and Research City College of New York 2002 Combinatorial Chemistry: A Guide for Librarians Philip Barnett CUNY City College How does access to this work benefit ou?y Let us know! More information about this work at: https://academicworks.cuny.edu/cc_pubs/266 Discover additional works at: https://academicworks.cuny.edu This work is made publicly available by the City University of New York (CUNY). Contact: [email protected] Issues in Science and Technology Librarianship Winter 2002 DOI:10.5062/F4DZ0690 URLs in this document have been updated. Links enclosed in{curly brackets} have been changed. If a replacement link was located, the new URL was added and the link is active; if a new site could not be identified, the broken link was removed. Combinatorial Chemistry: A Guide for Librarians Philip Barnett Associate Professor and Science Reference Librarian Science/Engineering Library City College of New York (CUNY) [email protected] Abstract In the 1980s a need to synthesize many chemical compounds rapidly and inexpensively spawned a new branch of chemistry known as combinatorial chemistry. While the techniques of this rapidly growing field are used primarily to find new candidate drugs, combinatorial chemistry is also finding other applications in various fields such as semiconductors, catalysts, and polymers. This guide for librarians explains the basics of combinatorial chemistry and elucidates the key information sources needed by combinatorial chemists. Introduction Most librarians who serve chemists or chemistry students are familiar with the six main disciplines of chemistry. These are: Physical chemistry applies the fundamental laws of physics, such as thermodynamics, electricity, and quantum mechanics, to explain chemical behavior. -
Chemistry and Biochemistry (CHBC) 1
Chemistry and Biochemistry (CHBC) 1 3. Each advanced degree candidate must present a suitable program Chemistry and of advanced courses and research. The specific courses needed to provide a basis for scholarly work beyond the B.S. level will vary with Biochemistry (CHBC) the student’s undergraduate preparation, area of concentration and the degree sought. Individual course enrollments must be approved initially by the graduate adviser and subsequently by the student’s Matt McIntosh advisory committee. Department Chair 119 Chemistry Building 4. Every student must register for a minimum of one credit hour of 479-575-4362 CHEM 600V or CHEM 700V in each term during which the student Email: [email protected] is present and doing thesis or dissertation research. Post-candidacy doctoral students are required to be enrolled in at least one hour Julie Stenken of dissertation credit (CHEM 700V) every semester (fall, spring, Director of Graduate Studies summer), until the degree is conferred. 119 Chemistry Building 479-575-7945 Additional Requirement for Master of Science Degree:The Master Email: [email protected] of Science degree in Chemistry requires a minimum 24 hours of course work plus six hours of thesis. A thesis reporting original research will be Department of Chemistry and Biochemistry Website (https:// required of all candidates for the Master of Science degree in chemistry. fulbright.uark.edu/departments/chemistry/) Students should also be aware of Graduate School requirements with Degrees Conferred: regard to master's degrees (http://catalog.uark.edu/graduatecatalog/ M.S., Ph.D. in Chemistry (CHEMMS, CHEMPH) degreerequirements/#mastersdegreestext). Areas of Study: Analytical, inorganic, organic, physical, biophysical, and Requirements for Ph.D. -
Mendeleev's Periodic Table of the Elements the Periodic Table Is Thus
An Introduction to General / Inorganic Chemistry Mendeleev’s Periodic Table of the Elements Dmitri Mendeleev born 1834 in the Soviet Union. In 1869 he organised the 63 known elements into a periodic table based on atomic masses. He predicted the existence and properties of unknown elements and pointed out accepted atomic weights that were in error. The periodic table is thus an arrangement of the elements in order of increasing atomic number. Elements are arranged in rows called periods. Elements with similar properties are placed in the same column. These columns are called groups. An Introduction to General / Inorganic Chemistry The modern day periodic table can be further divided into blocks. http://www.chemsoc.org/viselements/pages/periodic_table.html The s, p, d and f blocks This course only deals with the s and p blocks. The s block is concerned only with the filling of s orbitals and contains groups I and II which have recently been named 1 and 2. The p block is concerned only with the filling of p orbitals and contains groups III to VIII which have recently been named 13 to 18. An Introduction to General / Inorganic Chemistry Groups exist because the electronic configurations of the elements within each group are the same. Group Valence Electronic configuration 1 s1 2 s2 13 s2p1 14 s2p2 15 s2p3 16 s2p4 17 s2p5 18 s2p6 The type of chemistry exhibited by an element is reliant on the number of valence electrons, thus the chemistry displayed by elements within a given group is similar. Physical properties Elemental physical properties can also be related to electronic configuration as illustrated in the following four examples: An Introduction to General / Inorganic Chemistry 1. -
The Scope of Inorganic Chemistry
The Scope of Inorganic Chemistry Medicine Biochemistry/Biology Organic Chemistry •MRI • metalloproteins • organometallics •X-ray contrast imaging • metalloenzymes • metal compounds in •drugs (arthritis, cancer,… • O2 binding synthesis/catalysis • catalysis • ion transport INORGANIC CHEMISTRY • new compounds • geometrical and electronic structures • reactivity Materials Science Organometallic Geology/Geochemistry • electrical and magnetic Chemistry • synthesis and structure properties of solids • new compounds of minerals • solid state structures • structures • stellar evolution • semiconductors • catalysis • astrochemistry • superconductors (high Tc) If some universal catastrophe were to engulf the world, and humankind Could retain one scientific concept in order to rebuild civilization, what would that one concept be? Response for physicists (Richard Feynman in “Six Easy Pieces”): The modern idea of atoms. Response for chemists: The periodic table The periodic table encapsulates the concept of elements, organizes physical and chemical trends of substances, and compares the structure of the different atoms— All in a very small space. Inorganic Chemists think they own the Periodic Table. So, How did it all start? 4 8 Be with t1/2 of ca. 10-18 sec 6 2 4 3Li + 1H 2 2He + Energy Stable vs. Unstable or Fissionable Nuclei Project no. 1. Nuclear Reactions; Web Elements WebElementsTM Periodic Table Group 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 Period 1 2 1 H He 3 4 5 6 7 8 9 10 2 Li Be B C N O F Ne 11 12 13 14 15 16 17 18 3 Na Mg Al Si P