Intelligence and Heredity: Some Common Misconceptions
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Chemical, Biological, and Environmental Factors Responsible for The
CHEMICAL, BIOLOGICAL, AND ENVIRONMENTAL FACTORS RESPONSIBLE FOR THE - -v - - - IN THE AUBURN CITY WATER SUPPLY AGRICULTURAL EXPERIMENT STATION/AUBURN UNIVERSITY R. DENNIS ROUSE, DIRECTOR AUBURN, ALABAMA BULLETIN 490 JULY 1977 CONTENTS Page INTRODUCTION ........ .. .. ............... 3 Background on Odors of Biological Origin in Water .......................... 3 Odor in the Auburn Water ........................... 5 PROCEDURES ............................ 5 RESULTS AND DISCUSSION ........... ...... .......... 7 Biological Factors................................ 7 Chemical Factors ............................... 22 Environmental Factors Related to the Growth and Production of Odorous Substances by Actinomycetes ....... 24 Correlation of Rainfall, Temperature, and Threshold Odor Number (TON) ................... 39 SUMMARY ... ... ...................... ........... 41 REFERENCES ................... ....... ... .......... 45 FIRST PRINTING 3M, JULY 1977 ACKNOWLEDGEMENTS The authors wish to thank the Auburn Water Board for the financial support of this project, the Auburn Water Treatment Plant for supplying TON values, Dr. John Lawrence for use of the carbon analyzer, and Sandy Williams, Frank Seesock, and Susan Brownlee for technical assistance. Information contained herein is available to all without regard to race, color, or nationalorigin. CHEMICAL, BIOLOGICAL, and ENVIRONMENTAL FACTORS RESPONSIBLE for the EARTHY ODOR in the AUBURN CITY WATER SUPPLY J. D. WEETE, W. T. BLEVINS, G. R.WILT, and D. DURHAM' INTRODUCTION Background On Odors Of Biological Origin in Water HE OCCURRENCE of objectionable odors in water used for drinking and commercial purposes is well documented in certain regions of the United States (1, 4, 12, 15) and various other parts of the world. (1, 8, 9, 11). Odors in sur- face waters may originate from industrial and municipal sewage effluents or from biological activities of algae or heterotrophic microorganisms. Odors of biological origin may be due to decomposition of organisms or to the produc- tion of microbial metabolites. -
Commentary: Facing the Challenge of Gene-Environment Interaction: the Two-By-Four Table and Beyond
American Journal of Epidemiology Vol. 153, No. 10 Copyright © 2001 by The Johns Hopkins University School of Hygiene and Public Health Printed in U.S.A. All rights reserved The Challenge of Gene-Environment Interaction Botto and Khoury PRACTICE OF EPIDEMIOLOGY Commentary: Facing the Challenge of Gene-Environment Interaction: The Two-by-Four Table and Beyond Lorenzo D. Botto1 and Muin J. Khoury2 As a result of the Human Genome Project, epidemiologists can study thousands of genes and their interaction with the environment. The challenge is how to best present and analyze such studies of multiple genetic and environmental factors. The authors suggest emphasizing the fundamental core of gene-environment interaction—the separate assessment of the effects of individual and joint risk factors. In the simple analysis of one genotype and an exposure (both dichotomous), such study can be summarized in a two-by-four table. The advantages of such a table for data presentation and analysis are many: The table displays the data efficiently and highlights sample size issues; it allows for evaluation of the independent and joint roles of genotype and exposure on disease risk; and it emphasizes effect estimation over model testing. Researchers can easily estimate relative risks and attributable fractions and test different models of interaction. The two-by-four table is a useful tool for presenting, analyzing, and synthesizing data on gene-environment interaction. To highlight the role of gene-environment interaction in disease causation, the authors propose that the two-by-four table is the fundamental unit of epidemiologic analysis. Am J Epidemiol 2001;153:1016–20. -
Environmental Factors Affecting the Composition and Diversity of The
Imai et al. Journal of Ecology and Environment (2017) 41:8 Journal of Ecology DOI 10.1186/s41610-017-0027-2 and Environment RESEARCH Open Access Environmental factors affecting the composition and diversity of the avian community in igune, a traditional agricultural landscape in northern Japan Haruka Imai1*, Tohru Nakashizuka1,2 and Michio Oguro1,3 Abstract Background: “Igune,” a traditional agricultural landscape in the Tohoku region of Japan, is characterized by small-scale artificial woodlots surrounding a farmer’s house that are interspersed with paddy fields. During the rapid economic growth of Japan over recent decades, some igune woodlots have been abandoned or logged. Biodiversity conservation is an important issue worldwide, and traditional agricultural landscapes are of particular interest. To elucidate the role of igune landscapes in conserving biodiversity, we examined the effects of environmental factors on avian communities. Results: The study was conducted in the suburban areas of Oshu and Hanamaki cities, Iwate Prefecture, Japan, at eight sites that varied in the density and area of igune woodlots within the landscape. Bird surveys were conducted from the middle to late breeding season, and several environmental factors of the igune landscape were also measured. The results of canonical correspondence analysis indicated that the characteristics of avian communities were mainly determined by the total forested area in the landscape. Increased total forested area and shrubs layer of igune woodlots did not cause a reduction in number of bird species of any habitat and foraging types, while increased both in species number and abundance of insectivores and forest species. The number of raptor species increased in igune sites without shrubs. -
How Much Global Ill Health Is Attributable to Environmental Factors?
ORIGINAL ARTICLES How Much Global Ill Health Is Attributable to Environmental Factors? Kirk R. Smith,1 Carlos F. Corvalán2, and Tord Kjellström3 Over the years, estimates have been made of the portions of attributed to environmental risk factors. Children under 5 human mortality and morbidity that can be attributed to years of age seem to bear the largest environmental burden, environmental factors. Frustratingly, however, even for a and the portion of disease due to environmental risks seems single category of disease such as cancer, these estimates to decrease with economic development. A summary of have often varied widely. Here we attempt to explain why these estimates first appeared in the 1997 report, "Health such efforts have come to such different results in the past and Environment in Sustainable Development," which was and to provide guidance for doing such estimates more the World Health Organization's contribution to the 5-year consistently in the future to avoid the most important pitfalls. anniversary of the Rio Earth Summit. A full explanation of We do so by carefully defining what we mean by the terms how these estimates were made is first presented here. We "environmental," "ill health," and "attributable." Finally, end with a call for a program of "strategic epidemiology," based on these recommendations, we attempt our own which would be designed to fill important gaps in the estimate, appropriately qualified according to the many understanding of major environmental health risks in remaining uncertainties. Our estimate is that 25-33% of the important population groups worldwide. (Epidemiology global burden of disease can be 1999;10:573-584) Keywords: environmental exposures, morbidity, mortality, children, environmental health risks, populations, global factors, public health. -
Public Health Classifications Project – Determinants of Health
Public Health Classifications Project – Determinants of Health Phase Two: Final Report Acknowledgements We acknowledge the National Public Health Partnership for leading the first phase of work on public health classification; the New South Wales Department of Health and the Public Health Information Development Unit, the University of Adelaide for sponsoring this Project; colleagues from both for their support of the Project Officer; the Sax Institute for providing meeting premises and equipment; and the National Centre for Classification in Health for access to ICD-10, the 11th coding conference and opportunities to meet and discuss issues with ICD coders. NSW DEPARTMENT OF HEALTH 73 Miller Street NORTH SYDNEY NSW 2060 Tel. (02) 9391 9000 Fax. (02) 9391 9101 TTY. (02) 9391 9900 www.health.nsw.gov.au Report prepared for the New South Wales Department of Health Report prepared by Su Gruszin, the Project Officer; Louisa Jorm, the Chair of the Project Working Group; and Working Group members: Tim Churches, Richard Madden, Sarah Thackway, and Ros Madden. This work is copyright. It may be reproduced in whole or in part for study training purposes subject to the inclusion of an acknowledgement of the source. It may not be reproduced for commercial usage or sale. Reproduction for purposes other than those indicated above requires written permission from the NSW Department of Health. © NSW Department of Health 2010 SHPN (CER) 100195 ISBN 978-1-74187-461-7 Further copies of this document can be downloaded from the NSW Health website www.health.nsw.gov.au December 2010 Contents Executive Summary ................................................................. 3 Section 1: Introduction ............................................................. -
Bioactive Nutrients and Nutrigenomics in Age-Related Diseases
molecules Review Bioactive Nutrients and Nutrigenomics in Age-Related Diseases Tania Rescigno 1, Luigina Micolucci 2,3, Mario F. Tecce 1 and Anna Capasso 1,* 1 Department of Pharmacy, University of Salerno, Fisciano 84084, Italy; [email protected] (T.R.); [email protected] (M.F.T.) 2 Computational Pathology Unit, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona 60120, Italy; [email protected] 3 Laboratory of Experimental Pathology, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona 60120, Italy * Correspondence: [email protected]; Tel.: +39-089-989744 Academic Editor: Philippe Bulet Received: 18 November 2016; Accepted: 3 January 2017; Published: 8 January 2017 Abstract: The increased life expectancy and the expansion of the elderly population are stimulating research into aging. Aging may be viewed as a multifactorial process that results from the interaction of genetic and environmental factors, which include lifestyle. Human molecular processes are influenced by physiological pathways as well as exogenous factors, which include the diet. Dietary components have substantive effects on metabolic health; for instance, bioactive molecules capable of selectively modulating specific metabolic pathways affect the development/progression of cardiovascular and neoplastic disease. As bioactive nutrients are increasingly identified, their clinical and molecular chemopreventive effects are being characterized and systematic analyses encompassing the “omics” technologies (transcriptomics, proteomics and metabolomics) are being conducted to explore their action. The evolving field of molecular pathological epidemiology has unique strength to investigate the effects of dietary and lifestyle exposure on clinical outcomes. The mounting body of knowledge regarding diet-related health status and disease risk is expected to lead in the near future to the development of improved diagnostic procedures and therapeutic strategies targeting processes relevant to nutrition. -
The Exposome & Precision Medicine
Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai The Exposome & Precision Medicine “Everything that rises must converge” Flannery O’Connor Robert O. Wright MD MPH Ethel H Wise Professor and Chairman Department of Environmental Medicine Director: Mount Sinai Institute for Exposomics Icahn School of Medicine at Mount Sinai What is Precision Medicine? • NRC Definition – Tailoring of medical treatment to the characteristics of each patient. • classify individuals into subpopulations that differ in their susceptibility to a disease, prognosis, or response to a specific treatment. • Interventions are concentrated on those who benefit, sparing expense and side effects for those who will not. In essence, it means understanding the patient’s individual background - that influences disease severity, progression and response to treatment Operates in a setting where the Probability of illness = 1 (i.e. prevention no longer matters) The promise of precision medicine • Pharmacogenomics – Increased drug efficacy & decreased toxicity – Decreased exposure to ineffective drugs – Target therapy to the most effective drugs – Targeting of behavioral modifications based on individual risk factors • Improved counseling and decision making • Improved patient outcomes and satisfaction • Improved tolerance of therapy improve adherence But we know that genetics is only 1 piece of a much bigger puzzle Genes Behavior Nutrition Infections Chemicals Physical environment Culture/society Stress Introduction to the special issue in Science was entitled: “It's Not Just the Genes” Vol 296, 2002 Paula Kiberstis, Leslie Roberts For many programs in Precision Medicine, there is no mention of environment Complex Disease Research “So, how did we get here?” -David Byrne ADHD, Obesity, Asthma, COPD, Parkinson’s, Cancer etc. -
Galton, Terman, Cox: the Distinctive Volume II in Genetic Studies Of
GCQXXX10.1177/0016986220921360Gifted Child QuarterlySimonton 921360research-article2020 Article Gifted Child Quarterly 1 –10 Galton, Terman, Cox: © 2020 National Association for Gifted Children Article reuse guidelines: The Distinctive Volume II sagepub.com/journals-permissions DOI:https://doi.org/10.1177/0016986220921360 10.1177/0016986220921360 in Genetic Studies of Genius journals.sagepub.com/home/gcq Dean Keith Simonton1 Abstract With just one exception, all of the volumes in Terman’s Genetic Studies of Genius report the results of a longitudinal study of more than a thousand intellectually gifted children. That single exception is Volume II, Cox’s single-authored The Early Mental Traits of Three Hundred Geniuses, which instead was a retrospective study of 301 eminent creators and leaders, using historiometric methods to estimate their IQs (as well as to assess a subset of 100 on 67 character traits). This article discusses how this volume actually fits with the other four volumes in the set. After giving the historical background, discussion turns to the emergence of Cox’s doctoral dissertation. Then comes a narrative of the aftermath, including subsequent contributions by Cox, Terman, and numerous other researchers extending into the 21st century. The article closes by treating the ways that the intellectually gifted and the historic geniuses are not comparable, thus indicating the need for more recent replications and extensions of her work. Keywords archival, biographical, historical analysis, early childhood, gifted, intelligence Strictly speaking, Lewis M. Terman’s (1925-1959) monu- complete list of impressive big names provided on multiple mental and highly influential Genetic Studies of Genius con- occasions throughout the volume. -
The Impact of Environmental Factors As Quality Determinants in Medicinal Plants ⁎ B
Available online at www.sciencedirect.com South African Journal of Botany 82 (2012) 11–20 www.elsevier.com/locate/sajb Review Quality from the field: The impact of environmental factors as quality determinants in medicinal plants ⁎ B. Ncube, J.F. Finnie, J. Van Staden Research Centre for Plant Growth and Development, School of Life Sciences, University of KwaZulu-Natal Pietermaritzburg, Private Bag X01, Scottsville 3209, South Africa Available online 5 September 2012 Abstract Plants have been used extensively in both pharmaceutical and food industries, with consumers showing increasing interests in these products. Phytomedicines exploit a pool of biogenic resources produced by plants. However, the quality and quantity of these chemical metabolites in plants are influenced by a multitude of factors, chief among them, environmental. This review provides an overview of plant-produced chemical compounds with medicinal properties and how their production is affected by different environmental factors. An insight into how these factors can be manipulated within the plants' growing environments as a way of ensuring quality is also discussed. © 2012 SAAB. Published by Elsevier B.V. All rights reserved. Keywords: Environment; Phytomedicine; Quality; Secondary metabolite; Stress factors Contents 1. Introduction .............................................................. 11 2. Plant secondary metabolism ...................................................... 12 3. Environmental factors - a force behind secondary metabolism? ................................... -
Factors Influencing Health Outcomes Across the Least, Average and Healthiest States in America
Old Dominion University ODU Digital Commons School of Public Service Theses & Dissertations School of Public Service Summer 2017 Factors Influencing Health Outcomes Across the Least, Average and Healthiest States in America Somayeh Hooshmand Old Dominion University, [email protected] Follow this and additional works at: https://digitalcommons.odu.edu/publicservice_etds Part of the Public Administration Commons Recommended Citation Hooshmand, Somayeh. "Factors Influencing Health Outcomes Across the Least, Average and Healthiest States in America" (2017). Doctor of Philosophy (PhD), Dissertation, School of Public Service, Old Dominion University, DOI: 10.25777/sqdq-xm77 https://digitalcommons.odu.edu/publicservice_etds/7 This Dissertation is brought to you for free and open access by the School of Public Service at ODU Digital Commons. It has been accepted for inclusion in School of Public Service Theses & Dissertations by an authorized administrator of ODU Digital Commons. For more information, please contact [email protected]. FACTORS INFLUENCING HEALTH OUTCOMES ACROSS THE LEAST, AVERAGE AND HEALTHIEST STATES IN AMERICA by Somayeh Hooshmand B.A. May 2005, Chamran University of Ahvaz, Iran Ph.D. September 2014, Universiti Putra Malaysia, Malaysia A Dissertation Submitted to the Faculty of Old Dominion University in Partial Fulfillment of the Requirements for the Degree of DOCTOR OF PHILOSOPHY PUBLIC ADMINISTRATION AND POLICY OLD DOMINION UNIVERSITY August 2017 Approved by: Dr. John Morris (Director) Dr. Mohammad Najand (Member) Dr. -
Francis Galton
Journal ofMedical Ethics 1998;24:99-105 J Med Ethics: first published as 10.1136/jme.24.2.99 on 1 April 1998. Downloaded from Francis Galton: and eugenics today David J Galton, and Clare J Galton St Bartholomew's Hospital, London and Princess Alexandra Hospital, Brisbane, Queensland, Australia Abstract Laws proposes many social measures to improve Eugenics can be defined as the use ofscience applied the quality of future generations.' to the qualitative and quantitative improvement of Galton strongly believed, following on from the human genome. The subject was initiated by Darwin's theories of evolution and natural selec- Francis Galton with considerable support from tion, that "we should attempt to exert control over Charles Darwin in the latter half of the 19th century. organic evolution in the same way as we exert Its scope has increased enormously since the recent control over the physical world and to direct it into revolution in molecular genetics. Geneticfiles can be channels of our own choosing".4 This would pro- easily obtainedfor individuals either antenatally or at vide practical applications for Darwin's theories birth; somatic gene therapy has been introducedfor and replace his idea of natural selection by a type some rare inborn errors of metabolism; and gene of artificial selection. The publication of Darwin's manipulation ofhuman germ-line cells will no doubt Origin ofSpecies in 1859 and the elaboration ofhis occur in the nearfuture to generate organs for theory of evolution by natural selection provoked transplantation. both bitter theological controversies with the The past history ofeugenics has been appalling, creationist proponents of the animal world as well with gross abuses in the USA between 1931 and as spirited debates on its application to social copyright. -
Heredity and Hereditarianism
Philosophy of Education An Encyclopedia Editor J.J. Chambliss Garland Publishing, Inc. New York & London 1996 HEREDITY AND HEREDITARIANISM Barry Mehler Department of Humanities Ferris State University Big Rapids, MI 49307 2500 words. Heredity is usually defined as the genetic transmission of characteristics from parent to offspring. This, however, is an oversimplification. The child does not inherit characteristics or traits from its parents. Children do not inherit musical ability, criminal tendencies, or IQ. Neither do they inherit physical characteristics such as skin or hair color. The child inherits one set of allele's from each parent. Together they form the child's genotype. The child also inherits mitochondria which are outside the nucleus of the cell. Genes code for the production of proteins which in turn interact with the environment to produce a phenotype. What we refer to as traits or characteristics are the phenotypes. The human being in all his or her complexity is the result of this interaction of a unique genotype with a unique environment. The modern study of heredity began with the rediscovery in 1900 of the work of Gregor Mendel (1822-1884) by Hugo De Vries, Karl Correns, and Erich Tschermak. Mendel discovered the basic laws of segregation and independent assortment of paired alleles which opened the way for the modern science of genetics. The American geneticist, Thomas Hunt Morgan (1866-1945) carried on studies of heredity in Drosophila (fruit fly) and was awarded the Nobel prize in 1933 for his discoveries relating to the laws and mechanisms of heredity. Morgan showed the existence of genes located at specific sites on chromosomes.