JOURNAL OF VIROLOGY

Volume 61 October 1987 No. 10

ANIMAL VIRUSES Analysis of Pseudorabies Virus glll Localization and Modification by Using Novel Infectious Viral Mutants Carrying Unique EcoRI Sites. J. Patrick Ryan, Mary E. Whealy, Alan K. Robbins, and Lynn W. Enquist 2962-2972 Effects of Position and Orientation of the 72-Base-Pair-Repeat Transcriptional Enhancer on Replication from the Simian Virus 40 Core Origin. Settara C. Chandrasekharappa and Kiranur N. Subramanian ...... 2973-2980 Mutants of the Envelope Glycoprotein That Lack the Transmembrane Anchor and Cytoplasmic Domains: Analysis of Intracellular Transport and Assembly into Virions. Lautaro G. Perez, Gary L. Davis, and Eric Hunter...... 2981-2988 Sequences of Virus Type 1 That Inhibit Formation of Stable TK+ Transformants. Daniel H. Farkas, Timothy M. Block, Paul B. Hart, and Robert G. Hughes, Jr...... 2989-2996 Primer-Dependent Synthesis of Covalently Linked Dimeric RNA Molecules by Poliovirus Replicase. John M. Lubinski, Lynn J. Ransone, and Asim Dasgupta ...... 2997-3003 Adaptor Plasmids Simplify the Insertion of Foreign DNA into Helper-Independent Retroviral Vectors. Stephen H. Hughes, Jack J. Greenhouse, Christos J. Petropoulos, and Pramod Sutrave ...... 3004-3012 Point Mutation in the S Gene of for a d/y or w/r Subtypic Change in Two Blood Donors Carrying a Surface Antigen of Compound Subtype adyr or adwr. Hiroaki Okamoto, Mitsunobu Imai, Fumio Tsuda, Takeshi Tanaka, Yuzo Miyakawa, and Makoto Mayumi ...... 3030-3034 Hepatitis A Virus cDNA and Its RNA Transcripts Are Infectious in . Jeffrey 1. Cohen, John R. Ticehurst, Stephen M. Feinstone, Betsy Rosenblum, and Robert H. Purcell ...... 3035-3039 Isolation of a Herpes Simplex Virus cDNA Encoding the DNA Repair Uracil-DNA Glycosylase. Sal Caradonna, Diane Worrad, and Ron Lirette 3040-3047 Overlapping Sets of Viral RNAs Reflect the Array of Polypeptides in the EcoRI J and N Fragments (Map Positions 81.2 to 85.0) of the Autographa californica Nuclear Polyhedrosis Virus Genome. Cornelia Oellig, Brigitte Happ, Thomas Muller, and Walter Doerfler...... 3048-3057 Isolation and Characterization of Temperature-Sensitive Mutants of Adenovirus Type 7. J. Praszkier and H. S. Ginsberg ...... 3089-3095 A Recombinant Plasmid from Which an Infectious Adeno-Associated Virus Genome Can Be Excised In Vitro and Its Use To Study Viral Replication. Richard Jude Samulski, Long-Sheng Chang, and Thomas Shenk ...... 3096-3101 Expression of the Hepatitis B Virus Core Gene In Vitro and In Vivo. Thomas Weimer, Jochen Salfeld, and Hans Will ...... 3109-3113 Homotypic and Heterotypic Exclusion of Vesicular Stomatitis Virus Replication by High Levels of Recombinant Polymerase L. Ellen Meier, George G. Harmison, and Manfred Schubert ...... 3133-3142 Continued on following page Continued from preceding page

A Cytomegalovirus Protein with Properties of Herpes Simplex Virus ICP8: Partial Purification of the Polypeptide and Map Position of the Gene. George W. Kemble, A. Louise McCormick, Lenore Pereira, and Edward S. Mocarski 3143-3151 Molecular Genetic Analysis of a Virus Gene with an Essential Role in DNA Replication. Elizabeth Evans and Paula Traktman...... 3152-3162 Dissection of Immediate-Early Gene Promoters from Herpes Simplex Virus: Sequences That Respond to the Virus Transcriptional Activators. Irwin H. Gelman and Saul Silverstein ...... 3167-3172 Processing Determinants Required for In Vitro Cleavage of the Poliovirus P1 Pre- cursor to . Mary Frances Ypma-Wong and Bert L. Semler 3181-3189 Missense Mutations in the VP1 Gene of Simian Virus 40 That Compensate for Defects Caused by Deletions in the Viral Agnogene. Alice Barkan, Renee C. Welch, and Janet E. Mertz ...... 3190-3198 Proteolytic Processing of Foot-and-Mouth Disease Virus Polyproteins Expressed in a Cell-Free System from Clone-Derived Transcripts. Vikram N. Vakharia, Margaret A. Devaney, Douglas M. Moore, John J. Dunn, and Marvin J. Grubman ...... 3199-3207 Frequent Segregation of More-Defective Variants from a Rous Sarcoma Virus Packaging Mutant, TK15. Makoto Nishizawa, Takumi Koyama, and Sadaaki Kawai ...... 3208-3213 Identification and Characterization of the Human Cytomegalovirus Immediate- Early Region 2 Gene That Stimulates from an Inducible Promoter. Terry W. Hermiston, Cheryl L. Malone, Pamela R. Witte, and Mark F. Stinski ...... 3214-3221 Acylation of the 176R (19-Kilodalton) Early Region 1B Protein of Human Adenovirus Type 5. C. Jane McGlade, Michel L. Tremblay, Siu-Pok Yee, Rachel Ross, and Philip E. Branton ...... 3227-3234 Adenovirus Proteins Associated with mRNA and hnRNA in Infected HeLa Cells. Stephen A. Adam and Gideon Dreyfuss...... 3276-3283 Temporal Control of Bovine Herpesvirus 1 Glycoprotein Synthesis. G. V. Ludwig, and G. J. Letchworth III ...... 3292-3294 Integration of Human Papillomavirus Type 16 DNA Sequences: a Possible Early Event in the Progression of Genital Tumors. Sylvie Schneider-Maunoury, Odile Croissant, and Gerard Orth ...... 3295-3298 Both the Rightward and the Leftward Open Reading Frames within the BamHI M DNA Fragment of Epstein-Barr Virus Act as trans-Activators of Gene Expression. Mieko 0. Oguro, Norio Shimizu, Yasushi Ono, and Kenzo Takada...... 3310-3313 Action of 3-Methylquercetin on Poliovirus RNA Replication. Jose Luis Castrillo and Luis Carrasco ...... 3319-3321 Expression of the Precore Region of an Avian Hepatitis B Virus Is Not Required for Viral Replication. Christopher Chang, Greg Enders, Rolf Sprengel, Nick Peters, Harold E. Varmus, and Don Ganem ...... 3322-3325 Studies on the Origin-Specific DNA-Binding Domain of Simian Virus 40 Large T Antigen. Michael Strauss, Pedram Argani, Ian J. Mohr, and Yakov Gluzman ...... 3326-3330 Specific Immune Serum to the Epstein-Barr Virus DNA Polymerase. Robert G. Petit, Kiu Leung, and James E. Shaw ...... 3331-3334 Isolation and Characterization of Adenovirus Core Nucleoprotein Subunits. Michael E. Vayda and S. J. Flint...... 3335-3339

Continued on following page Continued from preceding page Mapping of the Gene Coding for Epstein-Barr Virus-Determined Nuclear Antigen EBNA3 and Its Transient Overexpression in a Human Cell Line by Using an Adenovirus Expression Vector. Irene Joab, David T. Rowe, Myriam Bodescot, Jean-Claude Nicolas, Paul J. Farrell, and Michel Perricaudet ... 3340-3344 VIRUS-CELL INTERACTIONS The Mouse Mammary Tumor Virus Long Terminal Repeat Directs Expression in Epithelial and Lymphoid Cells of Different Tissues in Transgenic Mice. Yongwon Choi, Denis Henrard, Inchul Lee, and Susan R. Ross ... 3013-3019 Transforming and Mitogenic Effects of Avian Leukemia Virus E26 on Chicken Hematopoietic Cells and Fibroblasts, Respectively, Correlate with Level of Expression of the Provirus. P. Jurdic, M. Benchaibi, 0. Gandrillon, and J. Samarut ...... 3058-3065 Transforming Potential of a myc-Containing Variant of Feline Leukemia Virus In Vitro in Early-Passage Feline Cells. Lynn Bonham, Patricia A. Lobelle-Rich, Lee A. Henderson, and Laura S. Levy ...... 3072-3081 Diverse Wild Mouse Origins of Xenotropic, Mink-Cell Focus-Forming, and Two Types of Ecotropic Proviral Genes. Christine A. Kozak and Raymond R. O'Neill ...... 3082-3088 Epstein-Barr Virus Gene Expression in P3HRl-Superinfected Raji Cells. Mark Biggin, Myriam Bodescot, Michel Perricaudet, and Paul Farrell ...... 3120-3132 Retroviral Vector Gene Expression in F9 Embryonal Carcinoma Cells. Elwood Linney, Suzanne D. Neill, and Dan S. Prestridge ...... 3248-3253 v-myb Does Not Prevent the Expression of c-myb in Avian Erythroblasts. Joseph S. Lipsick...... 3284-3287 Analysis of Middle Tumor Antigen and pp6O-csrc Interactions in Polyomavirus- Transformed Rat Cells. Joseph B. Bolen, Virginia DeSeau, Joyce O'Shaughnessy, and Shohreh Amini ...... 3299-3305 BACTERIAL VIRUSES Aberrant Regulation of Synthesis and Degradation of Viral Proteins in Coliphage X-Infected UV-Irradiated Cells and in Minicells. Jocelyn E. Shaw, Chris Epp, Mark L. Pearson, and John N. Reeve ...... 3254-3265 VIRAL PATHOGENESIS AND IMMUNITY Successful Infection of the Common Marmoset (Callithrixjacchus) with Human Varicella-Zoster Virus. Philip J. Provost, Paul Malcolm Keller, Franklyn S. Banker, Bernice J. Keech, Hilton J. Klein, Robert S. Lowe, David H. Morton, Andre H. Phelps, William J. McAleer, and Ronald W. Ellis ...... 2951-2955 Antigenic Analysis of Equine Infectious Anemia Virus (EIAV) Variants by Using Monoclonal Antibodies: Epitopes of Glycoprotein gp9O of EIAV Stimulate Neutralizing Antibodies. Khalid A. Hussain, Charles J. Issel, Kenneth L. Schnorr, Paul M. Rwambo, and Ronald C. Montelaro ...... 2956-2961 Nucleotide Sequence of a Complete Mouse Intracisternal A-Particle Genome: Relationship to Known Aspects of Particle Assembly and Function. Judy A. Mietz, Zehava Grossman, Kira K. Lueders, and Edward L. Kuff...... 3020-3029 Induction of Simian Acquired Immune Deficiency Syndrome (SAIDS) with a Molecular Clone of a Type D SAIDS . Gisela Heidecker, Nicholas W. Lerche, Linda J. Lowenstine, Andrew A. Lackner, Kent G. Osborn, Murray B. Gardner, and Preston A. Marx ...... 3066-3071

Continued on following page Continued from preceding page CD8-Positive T Lymphocytes Specific for Murine Cytomegalovirus Immediate- Early Antigens Mediate Protective Immunity. Matthias J. Reddehase, Wolfgang Mutter, Konrad Munch, Hans-Jorg Buhring, and Ulrich H. Koszinowski ...... 3102-3108 A Major Mechanism of Human Immunodeficiency Virus-Induced Cell Killing Does Not Involve Cell Fusion. M. Somasundaran and H. L. Robinson .... 3114-3119 Antigenic Relatedness between of Human Respiratory Syncytial Virus Subgroups A and B: Evaluation of the Contributions of F and G Glycoproteins to Immunity. Philip R. Johnson, Jr., Robert A. Olmsted, Gregory A. Prince, Brian R. Murphy, David W. Alling, Edward E. Walsh, and Peter L. Collins ...... 3163-3166 Persistent Infection of Chimpanzees with Human Immunodeficiency Virus: Serological Responses and Properties of Reisolated Viruses. Peter L. Nara, William G. Robey, Larry 0. Arthur, David M. Asher, Axel V. Wolff,

Clarence J. Gibbs, Jr., D. Carleton Gajdusek, and Peter J. Fischinger ..... 3173-3180 Transport of Infectious Reovirus into Bile: Class II Major Histocompatibility Antigen-Bearing Cells Determine Reovirus Transport. Donald H. Rubin, Teresa Costello, Cam L. Witzleben, and Mark I. Greene ...... 3222-3226 Temporal Distribution of Transmissible Mink Encephalopathy Virus in Mink Inoculated Subcutaneously. William J. Hadlow, Richard E. Race, and Richard C. Kennedy ...... 3235-3240 In Vitro Recombinants of Ground Squirrel and Woodchuck Hepatitis Viral DNAs Produce Infectious Virus in Squirrels. Christoph Seeger, Patricia L. Marion, Don Ganem, and Harold E. Varmus ...... 3241-3247 Important Role of the Long Terminal Repeat of the Helper Moloney in Abelson Virus-Induced Lymphoma. Pierre Savard, Luc DesGroseillers, Eric Rassart, Yves Poirier, and Paul Jolicoeur ...... 3266-3275 Novobiocin and Coumermycin A1 Inhibit Viral Replication and the Reactivation of Herpes Simplex Virus Type 1 from the Trigeminal Ganglia of Latently Infected Mice. Jordan G. Spivack, Donald R. O'Boyle II, and Nigel W. Fraser ...... 3288-3291 Biomolecular Analysis of a Defective Nontransforming Epstein-Barr Virus (EBV) from a Patient with Chronic Active EBV Infection. C. Alfieri and J. H. Joncas ...... 3306-3309 Immune Sera and Antiglycoprotein Monoclonal Antibodies Inhibit In Vitro Cell-to-Cell Spread of Pathogenic Rabies Viruses. Donald L. Lodmell and Larry C. Ewalt ...... 3314-3318 Persistent Infection in Mice with Severe Combined Immunodeficiency. Marie Riepenhoff-Talty, Tararaj Dharakul, Edward Kowalski, Susan Michalak, and Pearay L. Ogra ...... 3345-3348

Date of Issue: 15 September 1987