COX15 Antibody Cat. No.: 15-661

COX15 Antibody

Immunohistochemistry of paraffin-embedded rat spleen Immunohistochemistry of paraffin-embedded rat heart using COX15 antibody (15-661) at dilution of 1:100 (40x using COX15 antibody (15-661) at dilution of 1:100 (40x lens). lens).

Immunohistochemistry of paraffin-embedded human lung Immunohistochemistry of paraffin-embedded human cancer using COX15 antibody (15-661) at dilution of 1:100 thyroid cancer using COX15 antibody (15-661) at dilution (40x lens). of 1:100 (40x lens).

September 29, 2021 1 https://www.prosci-inc.com/cox15-antibody-15-661.html Immunohistochemistry of paraffin-embedded human Immunohistochemistry of paraffin-embedded mouse placenta using COX15 antibody (15-661) at dilution of 1:100 spleen using COX15 antibody (15-661) at dilution of (40x lens). 1:100 (40x lens).

Immunohistochemistry of paraffin-embedded mouse heart Immunofluorescence analysis of L929 cells using COX15 using COX15 antibody (15-661) at dilution of 1:100 (40x Polyclonal Antibody (15-661) at dilution of 1:100 (40x lens). lens). Blue: DAPI for nuclear staining.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 150-250 of human IMMUNOGEN: COX15 (NP_510870.1).

TESTED APPLICATIONS: IF, IHC, WB

WB: ,1:500 - 1:2000

APPLICATIONS: IHC: ,1:50 - 1:100

IF: ,1:50 - 1:100

POSITIVE CONTROL: 1) U-251MG

2) A-431

3) Jurkat

4) Mouse heart

5) Mouse kidney

6) Mouse lung

PREDICTED MOLECULAR Observed: 60kDa WEIGHT:

September 29, 2021 2 https://www.prosci-inc.com/cox15-antibody-15-661.html Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: COX15

ALTERNATE NAMES: COX15, CEMCOX2

GENE ID: 1355

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded BACKGROUND: subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates two transcript variants diverging in the 3' region.

ANTIBODIES FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.

September 29, 2021 3 https://www.prosci-inc.com/cox15-antibody-15-661.html