SUMMER 2015 3 Left to Right: Hani Bagheri (Phd Student), Emily Button (Phd Student), Samantha Burugu (Phd Student)
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PATHOLOGY Summer/Fall Edition 2015 MAGAZINE www.pathology.ubc.ca DEPARTMENT MEMBERS EXCELLENCE STATE OF THE ART ANNUAL EVENT Featuring Research Education Pathology Day Judith Lynn Isaac-Renton, Professor of BC Children’s Hospital BioBank We congratulate our graduates and Pathology Day 2015 was another Microbiology, Department of Pathology Open for Business! know that they will excel as they take terrific success this year, bringing and Laboratory Medicine, University of the next steps in their careers together students, staff, fellows and British Columbia faculty members PATHOLOGY DAY 2015. Left to right: Tyler Verdun (Resident - GP), Mary Kinloch (Clinical Fellow), Brandon Sheffield (Resident - AP), Tony Ng (Clinical Assistant Professor) PATHOLOGY PATHOLOGY MAGAZINE Department Head: 4 Pathology Day 2015 Michael F. Allard, BSc, MD, FRCP(C) Director, Human Resources and Administration: 9 2015 Academic Gowns Sandy Liu 10 Pathology Residency Program Office Manager: Adeline Chan 16 Anatomical Pathology Residency Training Program 20 Bachelor of Medical Laboratory Science (BMLSc) Program Contributors: Co-Chairs of Pathology Day 2015 22 Graduate Studies Mr. James Beresford 26 Pathology Arts Gala Dr. Susanna Zachara Dr. Michael Nimmo and Ms. JieJi Sun 30 This Summer Dr. Diana Ionescu Daniel Owen 32 Faculty Promotions and Tenure Awards in 2014/15 Dr. Haydn Pritchard & Ms. Heather Cheadle Dr. Amanda Bradley and Ms. Joanne Wouterse 33 Faculty Awards Dr. Nick Sunderland Dr. Muhammad Morshed 34 The Spotlight Dr. Jagbir Singh 36 Pathology & Laboratory Medicine Fraser Health (FH) Ms. Sandy Liu & Ms. Amelia Libonao Dr. Hélène Côté 38 Southern Medical Program Dr. Judith Lynn Isaac-Renton Dr. Arun Garg 39 Neonatal Hyperbilirubinemia Dr. Bibi Naghibi Torbati Dr. Li Wang 40 The new MICRO CT SCANNER Dr. Dragos M. Vasilescu Dr. David Goldfarb 42 A Big Summer for Lung Cancer Patients Dr. Suzanne Vercauteren 43 Reverse Innovation Brings Technology from Developing Dr. Nickolas Myles Dr. Stephen Yip & Dr. Brandon S. Sheffield Nations to Canada Ms. Jennifer Xenakis 44 BC Children’s Hospital BioBank Open for Business 46 Overdiagnosis and Overtreatment Copyright © 2015: Department of Pathology and Laboratory Medicine 48 Personalized OncoGenomics (POG) Initiative Publisher: PacBlue Printing 51 Uncovering Low Allelic Mutational Events in Somatic Editors: Debbie Bertanjoli, Michael Allard, Adeline Chan, & Maria Issa Mosaicism and Cancer – Why Bother Designer: Debbie Bertanjoli 52 Welcome to New Faculty Members BMLSc students made it to the Storm the Wall finals! 2 TECHNOLOGY DISCOUNTED n PRICING FOR ADOBE SOFTWARE REQUIREMENTS OFFERED TO ALL Currently only available for UBC STAFF AND UBC owned computers FACULTY ADOBE SOFTWARE and benefit from cost Bridge Flash Professional UBC IT offers Adobe savings of up to 87% per Edge Animate Muse product licenses for year. Fireworks After Effects faculty and staff on Flash Professional Flash Builder Premium campus at a significant Our current packages Muse InCopy discount. UBC clients include: Acrobat Pro Audition can subscribe to Adobe Package ($15/year) Master Collection Premiere Pro products for their license ($95/year) Lightroom annually, at a fraction Acrobat Pro Acrobat Pro Prelude of the cost of what a full Design and Web InDesign Speedgrade perpetual license used to Collection ($80/year) Photoshop cost. Since most Adobe Acrobat Pro Illustrator UBC students are products are upgraded InDesign Dreamweaver eligible for academic every two to three years, Photoshop Bridge rates for Adobe products clients can always work Illustrator Edge Animate through the UBC with the current release Dreamweaver Fireworks Bookstore. The current cost savings breakdown like this: PRODUCT BEFORE NOW SAVINGS PER YEAR SAVINGS OVER 3 YEARS ACROBAT $91 $15/year 84% 51% DESIGN & WEB PREMIUM $440 $80/year 82% 45% MASTER COLLECTION $735 $95/year 87% 61% PATHOLOGY MAGAZINE - SUMMER 2015 3 Left to right: Hani Bagheri (PhD student), Emily Button (PhD student), Samantha Burugu (PhD student) Left to right: Tyler Verdun (Resident - GP), Mary Kinloch (Clinical Fellow), Brandon Sheffield Left to right: Arash Samiei (MSc student) Karen Simmons (Resident - AP), Tony Ng (Clinical Assistant Professor) (MSc student), Jessica Morrice (MSc student) ANNUAL PATHOLOGY EVENT PATHOLOGY DAY 2015 Co-Chairs of Pathology Day 2015 Pathology Day 2015 was another bar for all of us. We look forward Dr. Mike Allard introduced terrific success this year, to including more department the day and our James Hogg bringing together students, members in the future, as lecturer, Dr. Don Brooks. staff, fellows and faculty at the a means to present junior Dr. Brooks has dedicated his Paetzold Education Centre at faculty and re-introduce our career to surface and polymer Vancouver General Hospital. more established researchers chemistry, particularly in More than 170 department and their achievements to our developing polymer constructs members participated in the growing department. for biomedical applications various sessions throughout including blood compatible the day. This demonstrates materials, blood plasma protein once again that Pathology substitutes and drug delivery Day is truly a great occasion for which his group is widely to experience the caliber recognized. Drawing on his and diversity of research vast experience he gave an taking place throughout our excellent talk entitled, “What’s department, both at the junior Polymer Science doing in a nice and established research levels. place like the Centre for Blood Shining the spotlight on our Research?” Dr. Brooks’ lecture local best and brightest allows was very well received and us to see the high quality of generated much discussion and research that is taking place in thoughtful questions from the our own backyard, raising the audience. DR. DON BROOKS, PHD “What’s polymer science doing in a nice place like the Centre for Blood Research?” 4 Following on its introduction abstract was invited to present a number were selected for last year, Pathology Day 2015 that research orally. This year presentation during either the showcased the research Dr. Hugo Horlings discussed Resident or Graduate Student programs of two local Faculty: his work on the current Oral Platform Sessions. The Dr. Cheryl Wellington discussed understanding of “Granulosa- weather was great and the sun her work on “Alzheimer’s Cell Tumor of the Ovary: a shone at the right time, allowing Disease and Traumatic Brain Molecularly Defined Entity.” attendants at the poster session Injury” and Dr. David Granville and accompanying luncheon shared “Granzymes in Aging Over 70 abstracts were to utilize the Medical Student and Impaired Wound Healing”. submitted by trainees and Alumni Centre courtyard for staff, highlighting the breadth networking and catching up New this year, the Postdoctoral of research topics throughout with people for social and Fellow with the top ranked the department; from these scientific discussion. k DR. DAVID GRANVILLE, DR. CHERYL DR. HUGO PHD WELLINGTON, PHD HORLINGS, MD, PHD “Granzymes in Aging “Alzheimer’s Disease “Granulosa-Cell Tumor of and Impaired Wound and Traumatic Brain the Ovary: a Molecularly Healing” Injury” Defined Entity” Next Pathology Day is May 27th, 2016 PATHOLOGY MAGAZINE - SUMMER 2015 5 ANNUAL PATHOLOGY EVENT CONT’D KEYNOTE SPEAKER The Keynote address “The Role of the Microbiota in Asthma.” was given by Dr. B. Brett Finlay, Professor in the Michael Smith Laboratories, and the Departments of Biochemistry and Molecular Biology and Microbiology and Immunology at the University of British Columbia. PhD Finlay, B. Brett Dr. Pathology Day concluded with a well-attended reception back at the Medical Student Alumni Centre. There was lovely music by a jazz trio while department members mingled over delicious appetizers and cocktails. The evening was interspersed with some fabulous draw prizes and a variety of awards. Trainee award recipients included: RESIDENT PRESENTATIONS: RESIDENT Trainee award recipients 2015 DR. BRANDON SHEFFIELD DR. INNA SEKIROV DR. LAWRENCE LEE 1st Place 2nd place 3rd place “Molecular Profiling of ER “Carbapenemase Producing “Histopathologic Grading of Weakly-Positive Breast Cancer” Organisms in British Appendiceal Goblet Cell Supervisor: Dr. Torsten Nielsen” Columbia, 2008-2014” Carcinoids Predicts Survival” Supervisor: Dr. Linda Hoang Supervisor: Dr. David Schaeffer GRADUATE STUDENT PRESENTATIONS: STUDENT GRADUATE MS. ROLINDA CARTER MR. GABRIEL FUNG MR. HANI BAGHERI MS. TISSA RAHIM Dutkevich Memorial Trust 1st place 2nd place 3rd place Graduate Student Seminar “Coxsackieviral Infection “Identifying the ’Driver’ Genes “ARNT2, a Neuroprotective Award Causes Cytoplasmic for Multi-systemic 2p15-16.1 Transcription Factor, as a for the best Graduate Student Aggregation and Cleavage of Microdeletion Syndrome Using Regulator of neurodegenerative TAR DNA Binding Protein-43” in vivo Zebrafish Assays” Processes in Models of Seminar course presentation Supervisor: Dr. Honglin Luo Supervisor: Dr. Evica Multiple Sclerosis” as judged by peers Rajcan-Separovic Supervisor: Dr. Jacqueline Quandt 6 G RADUATE STUDENT POSTER PRESENTATION AWARDS: PRESENTATION POSTER STUDENT RADUATE MR. BRENNAN WADSWORTH MR. ADAM YU MS. SIGRID ALVAREZ MS. ROLINDA CARTER “Detection of Transient “Examining DNAJC13 “Islet Expression of “Novel Role for Direct Tumour Hypoxia with a Novel Expression within the Interleukin-35 Protects from Xa Anticoagulants in Combination of Oxygen- Neurovascular Niche and Autoimmune Diabetes and Fibrinolysis”