M/S. Veer Chemie & Aromatics (P) Ltd. LIST of CONTENTS S.NO
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Aldrich FT-IR Collection Edition I Library
Aldrich FT-IR Collection Edition I Library Library Listing – 10,505 spectra This library is the original FT-IR spectral collection from Aldrich. It includes a wide variety of pure chemical compounds found in the Aldrich Handbook of Fine Chemicals. The Aldrich Collection of FT-IR Spectra Edition I library contains spectra of 10,505 pure compounds and is a subset of the Aldrich Collection of FT-IR Spectra Edition II library. All spectra were acquired by Sigma-Aldrich Co. and were processed by Thermo Fisher Scientific. Eight smaller Aldrich Material Specific Sub-Libraries are also available. Aldrich FT-IR Collection Edition I Index Compound Name Index Compound Name 3515 ((1R)-(ENDO,ANTI))-(+)-3- 928 (+)-LIMONENE OXIDE, 97%, BROMOCAMPHOR-8- SULFONIC MIXTURE OF CIS AND TRANS ACID, AMMONIUM SALT 209 (+)-LONGIFOLENE, 98+% 1708 ((1R)-ENDO)-(+)-3- 2283 (+)-MURAMIC ACID HYDRATE, BROMOCAMPHOR, 98% 98% 3516 ((1S)-(ENDO,ANTI))-(-)-3- 2966 (+)-N,N'- BROMOCAMPHOR-8- SULFONIC DIALLYLTARTARDIAMIDE, 99+% ACID, AMMONIUM SALT 2976 (+)-N-ACETYLMURAMIC ACID, 644 ((1S)-ENDO)-(-)-BORNEOL, 99% 97% 9587 (+)-11ALPHA-HYDROXY-17ALPHA- 965 (+)-NOE-LACTOL DIMER, 99+% METHYLTESTOSTERONE 5127 (+)-P-BROMOTETRAMISOLE 9590 (+)-11ALPHA- OXALATE, 99% HYDROXYPROGESTERONE, 95% 661 (+)-P-MENTH-1-EN-9-OL, 97%, 9588 (+)-17-METHYLTESTOSTERONE, MIXTURE OF ISOMERS 99% 730 (+)-PERSEITOL 8681 (+)-2'-DEOXYURIDINE, 99+% 7913 (+)-PILOCARPINE 7591 (+)-2,3-O-ISOPROPYLIDENE-2,3- HYDROCHLORIDE, 99% DIHYDROXY- 1,4- 5844 (+)-RUTIN HYDRATE, 95% BIS(DIPHENYLPHOSPHINO)BUT 9571 (+)-STIGMASTANOL -
Control of Growth by Picolinic Acid
Proc. Nati. Acad. Sci. USA Vol. 74, No. 7, pp. 2889-2893, July 1977 Cell Biology Control of growth by picolinic acid: Differential response of normal and transformed cells (cell synchrony/chelating agents/NAD+/pyridine derivatives/viral transformation) J. A. FERNANDEZ-POL*t, VINCENT H. BONO, JR.J, AND GEORGE S. JOHNSON* * Laboratory of Molecular Biology and * Laboratory of Medicinal Chemistry and Biology, National Cancer Institute, Bethesda, Maryland 20014 Communicated by Nathan 0. Kaplan, April 14, 1977 ABSTRACT Picolinic acid reversibly inhibits the growth under 95% air/5% CO2, humidified atmosphere, at 37°. The of cultured cells. Fourteen other pyridine derivatives were in- cell lines used are listed in Table 1. Unless otherwise indicated, effective or toxic. Untransformed normal rat kidney (NRK) cells cells were planted at 1.5 X 105 cells per dish. Twenty-four hours are reversibly arrested in the G1 stage of the growth cycle as later, media were replaced by new media with or shown by cell counts, mitotic index, [3H]thymidine incorpora- (treated) tion, and flow microfluorometry. Flow microfluorometry was without (control) picolinic acid. All cells lines were treated with used to monitor the effects of picolinic acid on numerous other picolinic acid at 1.5,2,2.5,3, and 4 mM and analyzed for 4 days cell lines. Normal cells are blocked in GI, whereas transformed with media change every other day. cells show responses that are dependent upon the transforming Cells were analyzed for DNA content by flow microfluo- virus and independent of species or origin of the cell line. Kir- rometry (FMF) after trypsinization and suspension in pro- sten sarcoma virus-transformed cells are blocked in GI. -
Aldrich Raman
Aldrich Raman Library Listing – 14,033 spectra This library represents the most comprehensive collection of FT-Raman spectral references available. It contains many common chemicals found in the Aldrich Handbook of Fine Chemicals. To create the Aldrich Raman Condensed Phase Library, 14,033 compounds found in the Aldrich Collection of FT-IR Spectra Edition II Library were excited with an Nd:YVO4 laser (1064 nm) using laser powers between 400 - 600 mW, measured at the sample. A Thermo FT-Raman spectrometer (with a Ge detector) was used to collect the Raman spectra. The spectra were saved in Raman Shift format. Aldrich Raman Index Compound Name Index Compound Name 4803 ((1R)-(ENDO,ANTI))-(+)-3- 4246 (+)-3-ISOPROPYL-7A- BROMOCAMPHOR-8- SULFONIC METHYLTETRAHYDRO- ACID, AMMONIUM SALT PYRROLO(2,1-B)OXAZOL-5(6H)- 2207 ((1R)-ENDO)-(+)-3- ONE, BROMOCAMPHOR, 98% 12568 (+)-4-CHOLESTEN-3-ONE, 98% 4804 ((1S)-(ENDO,ANTI))-(-)-3- 3774 (+)-5,6-O-CYCLOHEXYLIDENE-L- BROMOCAMPHOR-8- SULFONIC ASCORBIC ACID, 98% ACID, AMMONIUM SALT 11632 (+)-5-BROMO-2'-DEOXYURIDINE, 2208 ((1S)-ENDO)-(-)-3- 97% BROMOCAMPHOR, 98% 11634 (+)-5-FLUORODEOXYURIDINE, 769 ((1S)-ENDO)-(-)-BORNEOL, 99% 98+% 13454 ((2S,3S)-(+)- 11633 (+)-5-IODO-2'-DEOXYURIDINE, 98% BIS(DIPHENYLPHOSPHINO)- 4228 (+)-6-AMINOPENICILLANIC ACID, BUTANE)(N3-ALLYL)PD(II) CL04, 96% 97 8167 (+)-6-METHOXY-ALPHA-METHYL- 10297 ((3- 2- NAPHTHALENEACETIC ACID, DIMETHYLAMINO)PROPYL)TRIPH 98% ENYL- PHOSPHONIUM BROMIDE, 12586 (+)-ANDROSTA-1,4-DIENE-3,17- 99% DIONE, 98% 13458 ((R)-(+)-2,2'- 963 (+)-ARABINOGALACTAN BIS(DIPHENYLPHOSPHINO)-1,1'- -
1 Abietic Acid R Abrasive Silica for Polishing DR Acenaphthene M (LC
1 abietic acid R abrasive silica for polishing DR acenaphthene M (LC) acenaphthene quinone R acenaphthylene R acetal (see 1,1-diethoxyethane) acetaldehyde M (FC) acetaldehyde-d (CH3CDO) R acetaldehyde dimethyl acetal CH acetaldoxime R acetamide M (LC) acetamidinium chloride R acetamidoacrylic acid 2- NB acetamidobenzaldehyde p- R acetamidobenzenesulfonyl chloride 4- R acetamidodeoxythioglucopyranose triacetate 2- -2- -1- -β-D- 3,4,6- AB acetamidomethylthiazole 2- -4- PB acetanilide M (LC) acetazolamide R acetdimethylamide see dimethylacetamide, N,N- acethydrazide R acetic acid M (solv) acetic anhydride M (FC) acetmethylamide see methylacetamide, N- acetoacetamide R acetoacetanilide R acetoacetic acid, lithium salt R acetobromoglucose -α-D- NB acetohydroxamic acid R acetoin R acetol (hydroxyacetone) R acetonaphthalide (α)R acetone M (solv) acetone ,A.R. M (solv) acetone-d6 RM acetone cyanohydrin R acetonedicarboxylic acid ,dimethyl ester R acetonedicarboxylic acid -1,3- R acetone dimethyl acetal see dimethoxypropane 2,2- acetonitrile M (solv) acetonitrile-d3 RM acetonylacetone see hexanedione 2,5- acetonylbenzylhydroxycoumarin (3-(α- -4- R acetophenone M (LC) acetophenone oxime R acetophenone trimethylsilyl enol ether see phenyltrimethylsilyl... acetoxyacetone (oxopropyl acetate 2-) R acetoxybenzoic acid 4- DS acetoxynaphthoic acid 6- -2- R 2 acetylacetaldehyde dimethylacetal R acetylacetone (pentanedione -2,4-) M (C) acetylbenzonitrile p- R acetylbiphenyl 4- see phenylacetophenone, p- acetyl bromide M (FC) acetylbromothiophene 2- -5- -
Companion Handbook to the WHO Guidelines for the Programmatic Management of Drug-Resistant Tuberculosis ISBN 978 92 4 154880 9
Companion handbookCompanion tofor the the WHO programmatic guidelines management of drug-resistant tuberculosis Companion handbook to the WHO guidelines for the programmatic management of drug-resistant tuberculosis ISBN 978 92 4 154880 9 Companion handbook to the WHO guidelines for the programmatic management of drug-resistant tuberculosis This book is a companion handbook to existing WHO policy guidance on the management of multidrug-resistant tuberculosis, including the WHO guidelines for the programmatic management of drug-resistant tuberculosis, WHO interim policy guidance on the use of bedaquiline in the treatment of multidrug-resistant tuberculosis, and the WHO interim policy guidance on the use of delamanid in the treatment of multidrug-resistant tuberculosis which were developed in compliance with the process for evidence gathering, assessment and formulation of recommendations, as outlined in the WHO Handbook for Guideline Development (version March 2010; available at http://apps.who.int/iris/ bitstream/10665/75146/1/9789241548441_eng.pdf ). WHO Library Cataloguing-in-Publication Data Companion handbook to the WHO guidelines for the programmatic management of drug-resistant tuberculosis. 1.Antitubercular agents – administration and dosage. 2.Tuberculosis, Multidrug-Resistant – drug therapy. 3.Treatment outcome. 4.Guideline. I.World Health Organization. ISBN 978 92 4 154880 9 (NLM classification: WF 360) © World Health Organization 2014 All rights reserved. Publications of the World Health Organization are available on the WHO website (www.who.int) or can be purchased from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: [email protected]). Requests for permission to reproduce or translate WHO publications –whether for sale or for non-commercial distribution– should be addressed to WHO Press through the WHO website (www.who.int/about/licensing/copyright_form/en/index. -
Picolinic and Isonicotinic Acids: a Fourier Transform Microwave Spectroscopy Study
Subscriber access provided by UNIV OF CALIFORNIA SAN DIEGO LIBRARIES Article Picolinic and Isonicotinic Acids: a Fourier Transform Microwave Spectroscopy Study Isabel Peña, Marcelino Varela, Vanina Franco, Juan Carlos Lopez, Carlos Cabezas, and Jose Luis Alonso J. Phys. Chem. A, Just Accepted Manuscript • DOI: 10.1021/jp509823v • Publication Date (Web): 10 Nov 2014 Downloaded from http://pubs.acs.org on November 17, 2014 Just Accepted “Just Accepted” manuscripts have been peer-reviewed and accepted for publication. They are posted online prior to technical editing, formatting for publication and author proofing. The American Chemical Society provides “Just Accepted” as a free service to the research community to expedite the dissemination of scientific material as soon as possible after acceptance. “Just Accepted” manuscripts appear in full in PDF format accompanied by an HTML abstract. “Just Accepted” manuscripts have been fully peer reviewed, but should not be considered the official version of record. They are accessible to all readers and citable by the Digital Object Identifier (DOI®). “Just Accepted” is an optional service offered to authors. Therefore, the “Just Accepted” Web site may not include all articles that will be published in the journal. After a manuscript is technically edited and formatted, it will be removed from the “Just Accepted” Web site and published as an ASAP article. Note that technical editing may introduce minor changes to the manuscript text and/or graphics which could affect content, and all legal disclaimers and ethical guidelines that apply to the journal pertain. ACS cannot be held responsible for errors or consequences arising from the use of information contained in these “Just Accepted” manuscripts. -
Microbial Transformation of Isonicotinic Acid Hydrazide and Isonicotinic Acid by Sarcina Sp*
J. Biosci., Vol. 1, Number 2, June 1979, pp. 223–234. © Printed in India. Microbial transformation of isonicotinic acid hydrazide and isonicotinic acid by Sarcina sp* R. C. GUPTA and O. P. SHUKLA Division of Biochemistry, Central Drug Research Institute, Lucknow 226 001 † Present address : Regional Research Laboratory, Jorhat, Assam. MS received 20 November 1978; revised 22 February 1979 Abstract. Metabolism of isonicotinic acid and isoniazid by Sarcina sp. led to the formation of two metabolites which were characterised as 2-hydroxyisonicotinic acid and citrazinic acid. The blue pigment formed during fermentation was shown to be derived from the auto-oxidation of citrazinic acid. 2-Oxo-glutarate accumulated as the major keto acid when isonicotinic acid or isonicotinic acid hydrazide meta- bolism was inhibited by 1 mM sodium arsenite. Isonicotinic acid, 2-hydroxy- isonicotinic acid and 2-oxo-glutarate were oxidised by isonicotinic acid hydrazide or isonicotinic acid-grown cells; citrazinic acid was, however, not oxidised. Isoniazid hydrazine hydrolase, isonicotinic acid and 2-hydroxyisonicotinic acid hydroxylases were detected in the cell-free extract of Sarcina sp. grown on isonicotinic acid hydrazide or isonicotinic acid. Keywords. Microbial transformation; isoniazid; isonicotinic acid; Sarcina. Introduction Metabolism of isonicotinic acid (INA) and N-methylisonicotinic acid has been investigated by Ensign and Rittenberg (1965), Orpin et al. (1972) and Wright and Cain (1972). Fishbain et al. (1972) reported the hydrolysis of isonicotinic acid hydrazide (INH) to INA and hydrazine by Mycobacterium smegmatis, but INA was not metabolised further. Metabolism of INH by M. tuberculosis has been reported to yield isonicotinic acid, pyridine-4-aldehyde and pyridine-4- methanol (Krishna Murti, 1974). -
Production of Isonicotinic Acid Using Agar Entrapped Whole Cells of Nocardia Globerula NHB-2 Bhalla T. C., Mehta P.K., Sharma N
XVIIth International Conference on Bioencapsulation, Groningen, Netherlands ; September 24-26, 2009 XVIIth International Conference on Bioencapsulation, Groningen, Netherlands ; September 24-26, 2009 Production of isonicotinic acid using agar entrapped whole cells of Nocardia isobutyronitrile in the growth medium containing 1% glucose, 0.5 % peptone, 0.3% beef extract globerula NHB-2 and 0.1% yeast extract , pH 7.5(Sharma N.N., 2009). The organism was cultured at 30°C in an incubator shaker at 160 rpm. The cells were sedimented at 10000 ‘g’ and suspended in 0.1M sodium Bhalla T. C., Mehta P.K., Sharma N.N. and Bhatia S.K. phosphate buffer, pH 7.5 and were termed as resting whole cells. The nitrilase activity of the Department of Biotechnology, Himachal Pradesh University, Summer Hill, resting cells was assayed as reported earlier using 4-cyanopyridine as substrate (Sharma N.N. et al. Shimla-171005, Himachal Pradesh, INDIA [email protected] 2006). One unit of nitrilase activity was defined as that amount of enzyme (whole cells) which catalyzed the conversion of one µ mole of 4-cyanopyrine to isonicotinic acid per min under the INTRODUCTION assay conditions. Isonicotinic acid or pyridine-4-carboxylic acid is an important pyridine derivative which is mainly The whole cells of N. globerula NHB-2 were immobilized in agar (1%, w/v) and small beads (4 used for the synthsis of isoniazid (an antituberculastic drug), inabenfide (a plant growth regulator), mm x 2.5 mm) were prepared following the methods described previously (Raj J. et al. 2007). The terefenadine (an antihistamine) and nialamide (an antidepressant) (Yadav G.D. -
Table of Contents
MONTANA TECH i CHEMICAL HYGIENE PLAN TABLE OF CONTENTS TABLE OF CONTENTS .......................................................................................... i STATEMENT OF POLICY .................................................................................... 1 CHEMICAL HYGIENE RESPONSIBILITIES ........................................................ 2 LABORATORY FACILITIES ................................................................................. 4 Maintenance ..................................................................................................... 4 Evaluation ......................................................................................................... 5 CONTROL MEASURES ....................................................................................... 5 Work Habits ...................................................................................................... 5 Laboratory Hygiene ........................................................................................... 6 Engineering Controls ........................................................................................ 6 Instrument Equipment and Use ........................................................................ 7 Personal Protective Equipment (PPE) .............................................................. 8 Eye Protection ............................................................................................. 8 Hand Protection .......................................................................................... -
Industrial Chemicals, Ashfords Dictionary, Chemical Name Index
2 Chemical name index A A ACA 4-AA ACA AA ACAC AA acamprosate calcium AAA acarbose AABA ACB AADMC 7-ACCA AAEM ACE AAMX acebutolol AAOA aceclidine AAOC aceclofenac AAOT acemetacin AAPP acenaphthene AAPT acenocoumarol 4-ABA acephate ABA acepromazine abacavir acequinocyl ABAH acesulfame-K abamectin acetaldehyde ABFA acetaldehyde ethyl phenethyl diacetal ABL acetaldehyde oxime ABPA acetaldehyde n-propyl phenethyl diacetal ABS acetaldoxime ABS acetal resins O-ABTF acetal resins P-ABTF acetamide ACN acetamidine hydrochloride 7-ACA 5-acetamido-2-aminobenzenesulfonic acid 7-ANCA 6-acetamido-2-aminophenol-4-sulfonic acid Name Index: Ashford’s Dictionary of Industrial Chemicals 3-acetamidoaniline 3-acetamidoaniline acetic acid, s-butyl ester 4-acetamidoaniline acetic acid, calcium salt p-acetamidoanisole acetic acid, chromium salt 4-acetamidobenzenesulfonyl chloride acetic acid, cinnamyl ester 2-acetamidocinnamic acid acetic acid, citronellyl ester 3-acetamido-2-hydroxyaniline-5-sulfonic acid acetic acid, cobalt salt 1-acetamido-7-hydroxynaphthalene acetic acid, decahydro-β-naphthyl ester 8-acetamido-1-hydroxynaphthalene-3,6-disulfonic acid acetic acid, dicyclopentenyl ester 1-acetamido-7-naphthol acetic acid, diethylene glycol monobutyl ether ester 4-acetamidonitrobenzene acetic acid, 2-ethoxyethyl ester p-acetamidophenol acetic acid, ethoxypropyl ester 3-acetamidopropylsulfonic acid, calcium salt acetic acid, ethyl diglycol ester 5-acetamido-2,4,6-triiodo-N-methylisophthalamic acid acetic acid, ethylene glycol diester 4-acetamido-2-ethoxybenzoic -
Reactions of 1-Methyl-4-Halo-4-Piperidyl Phenyl Ketone and Derivatives
University of New Hampshire University of New Hampshire Scholars' Repository Doctoral Dissertations Student Scholarship Spring 1958 REACTIONS OF 1-METHYL-4-HALO-4-PIPERIDYL PHENYL KETONE AND DERIVATIVES HENRY JOSEPH TROSCIANIEC Follow this and additional works at: https://scholars.unh.edu/dissertation Recommended Citation TROSCIANIEC, HENRY JOSEPH, "REACTIONS OF 1-METHYL-4-HALO-4-PIPERIDYL PHENYL KETONE AND DERIVATIVES" (1958). Doctoral Dissertations. 755. https://scholars.unh.edu/dissertation/755 This Dissertation is brought to you for free and open access by the Student Scholarship at University of New Hampshire Scholars' Repository. It has been accepted for inclusion in Doctoral Dissertations by an authorized administrator of University of New Hampshire Scholars' Repository. For more information, please contact [email protected]. REACTIONS OF 1-METHYL-4-HALO-4-PIPERIDYL PHENYL KETONE AND DERIVATIVES BY HENRY JOSEPH TROSCIANIEC B. S., St, Lawrence University, 1952 M. S., University of New Hampshire, 1955 A THESIS Submitted to the University of New Hampshire In Partial Fulfillment of The Requirements for the Degree of Doctor of Philosophy Graduate School Department of Chemistry June, 1958 Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. This thesis has been examined and approved. I / j ! ( A m c . j p b \) f p . '■ U ' "t-v -L. b i Datft Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. ACKNOWLEDGEMENT The research for this thesis was performed in the chemical laboratories of the University of New Hampshire. The completion of the thesis left the author indebted to Dr. Paul R. Jones who made the determinations of the infrared absorption spectra and Dr. -
(12) United States Patent (10) Patent No.: US 6,734,309 B1 Ray Et Al
USOO6734309B1 (12) United States Patent (10) Patent No.: US 6,734,309 B1 Ray et al. (45) Date of Patent: May 11, 2004 (54) PROCESS FOR THE SYNTHESIS OF FOREIGN PATENT DOCUMENTS SONICOTINIC ACID HYDRAZIDE DE 1116 667 11/1961 (75) Inventors: Subhash Chandra Ray, Dhanbad (IN); Lakshmi Narayan Nandi, Dhanbad OTHER PUBLICATIONS (IN); Baldev Singh, Dhanbad (IN); Hiralal Prasad, Dhanbad (IN); Sumant Maharaj, Dhanbad (IN); Prodyot Database CrossFire Beilstein Online Beilstein Institut Zur Kumar Sarkar, Dhanbad (IN); Forderung der Chemischen Wissenschaften, Frankfurt am Pashupati Dutta, Dhanbad (IN); Main, DE; Database accession No. Reaction ID: 329566 Shyam Kishore Roy, Dhanbad (IN); XP002237627. Abstract & Dzhumauleva, S.A., et al Russ. Satya Niketan Yadav, Dhanbad (IN); J. Phys. Chem. vol. 67, No. 5 (1993) pp. 976–977. Anup Kumar Bandyopadhyay, Dhanbad (IN) Database WPI Section Ch, Week 199627 Derwent Publica tions Ltd., London, GB; Class BO3, AN 1996–266597 (73) ASSignee: Council of Scientific and Industrial XP002237628 & SU 1197396 (Orozhonikidze Chem Pharm Research, New Delhi (IN) Inst) (1995) col. 1, line 52–67, Ex. 2. Notice: Subject to any disclaimer, the term of this patent is extended or adjusted under 35 U.S.C. 154(b) by 0 days. Primary Examiner Patricia L. Morris (74) Attorney, Agent, or Firm-Ladas & Parry (21) Appl. No.: 10/393,372 (57) ABSTRACT (22) Filed: Mar 20, 2003 The invention provides a process for the manufacture of Int. C.7. - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - C07D 213/56 (51) isonicotinic acid hydrazide(INH) useful in the treatment of (52) - - - - - - - - - - - - 546/316 tuberculosis. The invention relates to the Single Step con (58) Field of Search .........................................