Citation Characterization and Impact Normalization in Bioinformatics Journals
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From Within Host Dynamics to the Epidemiology of Infectious Disease: Scientific Overview and Challenges Juan B
From within host dynamics to the epidemiology of infectious disease: Scientific overview and challenges Juan B. Gutierrez, University of Georgia Mary Galinski, Emory University Stephen Cantrell, University of Miami Eberhard Voit, Emory University Journal Title: Mathematical Biosciences Volume: Volume 270, Number Pt B Publisher: Elsevier | 2015-12-01, Pages 143-155 Type of Work: Article | Post-print: After Peer Review Publisher DOI: 10.1016/j.mbs.2015.10.002 Permanent URL: https://pid.emory.edu/ark:/25593/rwj4r Final published version: http://dx.doi.org/10.1016/j.mbs.2015.10.002 Copyright information: © 2015 Published by Elsevier B.V. This is an Open Access work distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/). Accessed September 30, 2021 3:17 AM EDT HHS Public Access Author manuscript Author Manuscript Author ManuscriptMath Biosci Author Manuscript. Author manuscript; Author Manuscript available in PMC 2016 December 01. Published in final edited form as: Math Biosci. 2015 December ; 270(0 0): 143–155. doi:10.1016/j.mbs.2015.10.002. From Within Host Dynamics to the Epidemiology of Infectious Disease: Scientific Overview and Challenges Juan B. Gutierrez1, Mary R. Galinski2, Stephen Cantrell3, and Eberhard O. Voit4,* 1 Department of Mathematics, Institute of Bioinformatics, University of Georgia, Athens, GA 30602 2 Emory University School of Medicine, Division of Infectious Diseases, Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, 954 Gatewood Rd, Atlanta, GA 30329 3 Department of Mathematics, University of Miami, Coral Gables, FL 33124 4 Department of Biomedical Engineering, Georgia Institute of Technology, 313 Ferst Drive, Suite 4103, Atlanta, GA 30332-0535 Abstract Since their earliest days, humans have been struggling with infectious diseases. -
Normalization and Variance Stabilization of Single-Cell RNA-Seq Data Using Regularized Negative Binomial Regression Christoph Hafemeister1* and Rahul Satija1,2*
Hafemeister and Satija Genome Biology (2019) 20:296 https://doi.org/10.1186/s13059-019-1874-1 Method Open Access Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression Christoph Hafemeister1* and Rahul Satija1,2* Abstract Single-cell RNA-seq (scRNA-seq) data exhibits significant cell-to-cell variation due to technical factors, including the number of molecules detected in each cell, which can confound biological heterogeneity with technical effects. To address this, we present a modeling framework for the normalization and variance stabilization of molecular count data from scRNA-seq experiments. We propose that the Pearson residuals from “regularized negative binomial regression,” where cellular sequencing depth is utilized as a covariate in a generalized linear model, successfully remove the influence of technical characteristics from downstream analyses while preserving biological heterogeneity. Importantly, we show that an unconstrained negative binomial model may overfit scRNA-seq data, and overcome this by pooling information across genes with similar abundances to obtain stable parameter estimates. Our procedure omits the need for heuristic steps including pseudocount addition or log-transformation and improves common downstream analytical tasks such as variable gene selection, dimensional reduction, and differential expression. Our approach can be applied to any UMI-based scRNA-seq dataset and is freely available as part of the R package sctransform, with a direct interface to our single-cell toolkit Seurat. Keywords: Single-cell RNA-seq, Normalization Introduction sampling during sequencing also contribute significantly, In the analysis and interpretation of single-cell RNA- necessitating technical correction [4]. These same chal- seq (scRNA-seq) data, effective pre-processing and nor- lenges apply to bulk RNA-seq workflows, but are exac- malization represent key challenges. -
Journal of Biology Celebrates Its Fifth Anniversary Biomedcentral
BioMed Central Editorial Journal of Biology celebrates its fifth anniversary Published: 29 June 2007 Journal of Biology 2007, 6:5 The electronic version of this article is the complete one and can be found online at http://jbiol.com/content/6/3/5 © 2007 BioMed Central Ltd Five years ago this month, Journal of have been cited and accessed. Publish- an article by Mark Noble and col- Biology was launched under the guid- ing on average only every two months leagues provided evidence that brain ance of Editor-in-Chief Martin Raff has its perils, however: both authors cells are susceptible to chemotherapy and Editor Theodora Bloom as the and readers told us that they’d be [10]; the article has been downloaded premier biology journal of the open happier to see a journal that wasn’t so more than 5,000 times from the access publisher BioMed Central, the very selective and published more Journal of Biology site with a flurry of publisher of Genome Biology and the often. The journal is now planning to media interest. BMC series of journals. As we cele- build on its success in publishing Of course, for many authors, brate Journal of Biology’s birthday, we high-quality articles and is striving to readers and institutions there is one take this opportunity to reflect on the increase the rate of publication, while measure that matters above all others first five years during which the maintaining a very high standard. in evaluating a journal: the impact journal has published articles of factor, as determined by The Thomson exceptional interest across the full Corporation (ISI). -
Purifying Selection of Long Dsrna Is the First Line of Defense Against False Activation of Innate Immunity Michal Barak1, Hagit T
Barak et al. Genome Biology (2020) 21:26 https://doi.org/10.1186/s13059-020-1937-3 RESEARCH Open Access Purifying selection of long dsRNA is the first line of defense against false activation of innate immunity Michal Barak1, Hagit T. Porath1, Gilad Finkelstein1, Binyamin A. Knisbacher1, Ilana Buchumenski1, Shalom Hillel Roth1, Erez Y. Levanon1*† and Eli Eisenberg2*† Abstract Background: Mobile elements comprise a large fraction of metazoan genomes. Accumulation of mobile elements is bound to produce multiple putative double-stranded RNA (dsRNA) structures within the transcriptome. These endogenous dsRNA structures resemble viral RNA and may trigger false activation of the innate immune response, leading to severe damage to the host cell. Adenosine to inosine (A-to-I) RNA editing is a common post- transcriptional modification, abundant within repetitive elements of all metazoans. It was recently shown that a key function of A-to-I RNA editing by ADAR1 is to suppress the immunogenic response by endogenous dsRNAs. Results: Here, we analyze the transcriptomes of dozens of species across the Metazoa and identify a strong genomic selection against endogenous dsRNAs, resulting in their purification from the canonical transcriptome. This purifying selection is especially strong for long and nearly perfect dsRNAs. These are almost absent from mRNAs, but not pre-mRNAs, supporting the notion of selection due to cytoplasmic processes. The few long and nearly perfect structures found in human transcripts are weakly expressed and often heavily edited. Conclusion: Purifying selection of long dsRNA is an important defense mechanism against false activation of innate immunity. This newly identified principle governs the integration of mobile elements into the genome, a major driving force of genome evolution. -
Tracking the Popularity and Outcomes of All Biorxiv Preprints
bioRxiv preprint doi: https://doi.org/10.1101/515643; this version posted January 13, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-ND 4.0 International license. 1 Tracking the popularity and outcomes of all bioRxiv preprints 2 Richard J. Abdill1 and Ran Blekhman1,2 3 1 – Department of Genetics, Cell Biology, and Development, University of Minnesota, 4 Minneapolis, MN 5 2 – Department of Ecology, Evolution, and Behavior, University of Minnesota, St. Paul, 6 MN 7 8 ORCID iDs 9 RJA: https://orcid.org/0000-0001-9565-5832 10 RB: https://orcid.org/0000-0003-3218-613X 11 12 Correspondence 13 Ran Blekhman, PhD 14 University of Minnesota 15 MCB 6-126 16 420 Washington Avenue SE 17 Minneapolis, MN 55455 18 Email: [email protected] 1 bioRxiv preprint doi: https://doi.org/10.1101/515643; this version posted January 13, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-ND 4.0 International license. 19 Abstract 20 Researchers in the life sciences are posting their Work to preprint servers at an 21 unprecedented and increasing rate, sharing papers online before (or instead of) 22 publication in peer-revieWed journals. Though the popularity and practical benefits of 23 preprints are driving policy changes at journals and funding organizations, there is little 24 bibliometric data available to measure trends in their usage. -
Print Special Issue Flyer
IMPACT FACTOR 4.096 an Open Access Journal by MDPI Chromosome-Centric View of the Genome Organization and Evolution Guest Editors: Message from the Guest Editors Prof. Dr. Maria Sharakhova Dear Colleagues, Fralin Life Science Institute, The development of next generation sequencing Virginia Tech, Blacksburg, VA, USA technologies in the last decade has led to obtaining highly- fragmented genome assemblies for numerous organisms. [email protected] The quality of genome assemblies significantly varies Dr. Vladimir Trifonov among species, depending of the abundance of the Institute of Molecular and repetitive elements and levels of genetic polymorphism. As Cellular Biology of the Siberian a result, many important problems in genome biology Branch of the Russian Academy of Sciences (IMCB SB RAS), remain unresolved, without understanding how the 630090 Novosibirsk, Russia genome is organized at the level of the chromosomes. [email protected] Recent advances in genome and chromosome technologies, including long-read sequencing, Hi-C scaffoding, chromosome flow sorting, and physical and optical mapping, allow for obtaining genome assemblies Deadline for manuscript at the level of complete chromosomes. Such assemblies submissions: closed (30 April 2021) provide new opportunities to study chromosome organization and evolution, structural genome variations, sex-biased gene expression, epigenomic modifications, and long-range chromatin interactions. In this Special Issue, we would like to invite submissions of original research and review articles, with a special focus on chromosomes in our understanding of the genome structure, function, and evolution. mdpi.com/si/32917 SpeciaIslsue IMPACT FACTOR 4.096 an Open Access Journal by MDPI Editor-in-Chief Message from the Editor-in-Chief Prof. -
Genome Biology (2015) 16:6 DOI 10.1186/S13059-014-0577-X
Kelly et al. Genome Biology (2015) 16:6 DOI 10.1186/s13059-014-0577-x METHOD Open Access Churchill: an ultra-fast, deterministic, highly scalable and balanced parallelization strategy for the discovery of human genetic variation in clinical and population-scale genomics Benjamin J Kelly1, James R Fitch1, Yangqiu Hu1, Donald J Corsmeier1, Huachun Zhong1, Amy N Wetzel1, Russell D Nordquist1, David L Newsom1ˆ and Peter White1,2* Abstract While advances in genome sequencing technology make population-scale genomics a possibility, current approaches for analysis of these data rely upon parallelization strategies that have limited scalability, complex implementation and lack reproducibility. Churchill, a balanced regional parallelization strategy, overcomes these challenges, fully automating the multiple steps required to go from raw sequencing reads to variant discovery. Through implementation of novel deterministic parallelization techniques, Churchill allows computationally efficient analysis of a high-depth whole genome sample in less than two hours. The method is highly scalable, enabling full analysis of the 1000 Genomes raw sequence dataset in a week using cloud resources. http://churchill.nchri.org/. Background as sequencing costs decline and the rate at which sequence Next generation sequencing (NGS) has revolutionized data are generated continues to grow exponentially. genetic research, enabling dramatic increases in the dis- Current best practice for resequencing requires that a covery of new functional variants in syndromic and sample be sequenced to a depth of at least 30× coverage, common diseases [1]. NGS has been widely adopted by approximately 1 billion short reads, giving a total of 100 the research community [2] and is rapidly being imple- gigabases of raw FASTQ output [4]. -
Biomed Central Open-Access Research That Covers a Broad Range of Disciplines, and Reaches Influencers and Decision Makers
The Open Access Publisher 2017 Media Kit BioMed Central Open-access research that covers a broad range of disciplines, and reaches influencers and decision makers. CHEMISTRY SPRINGER NATURE.................2 - BIOCHEMISTRY - GENERAL CHEMISTRY OUR SOLUTIONS.....................3 HEALTH JOURNALS & DISCIPLINES......5 - HEALTH SERVICES RESEARCH - PUBLIC HEALTH BIOLOGY - BIOINFORMATICS - CELL & MOLECULAR BIOLOGY - GENERICS AND GENOMICS - NEUROSCIENCE MEDICINE - CANCER - CARDIOVASCULAR DISORDERS - CRITICAL, INTENSIVE CARE AND EMERGENCY MEDICINE - IMMUNOLOGY - INFECTIOUS DISEASES SPRINGER NATURE SPRINGER NATURE QUALITY CONTENT RESEARCHERS, CLINICIANS, DOCTORS Springer Nature is a leading publisher of scientific, scholarly, professional EARLY-CAREER and educational content. For over a century, our brands have been setting the 20 JOURNALS RANK #1 PROFESSORS, SCIENTISTS, IN 1 OR MORE SUBJECT LIBRARIANS, scientific agenda. We’ve published ground-breaking work on many fundamental STUDENTS CATEGORY* EDUCATORS achievements, including the splitting of the atom, the structure of DNA, and the 9 OF THE TOP 20 SCIENCE JOURNALS BY IMPACT discovery of the hole in the ozone layer, as well as the latest advances in stem- FACTOR* MORE NOBEL LAUREATES cell research and the results of the ENCODE project. BOARD-LEVEL PUBLISHED WITH US THAN ANY POLICY-MAKERS, SENIOR MANAGERS OTHER SCIENTIFIC PUBLISHER OPINION LEADERS Our dominance in the scientific publishing market comes from a company- wide philosophy to uphold the highest level of quality for our readers, authors -
Source Publication List for Web of Science
SOURCE PUBLICATION LIST FOR WEB OF SCIENCE SCIENCE CITATION INDEX EXPANDED Updated July 2017 Journal Title Publisher ISSN E-ISSN Country Language 2D Materials IOP PUBLISHING LTD 2053-1583 2053-1583 ENGLAND English 3 Biotech SPRINGER HEIDELBERG 2190-572X 2190-5738 GERMANY English 3D Printing and Additive Manufacturing MARY ANN LIEBERT, INC 2329-7662 2329-7670 UNITED STATES English 4OR-A Quarterly Journal of Operations Research SPRINGER HEIDELBERG 1619-4500 1614-2411 GERMANY English AAPG BULLETIN AMER ASSOC PETROLEUM GEOLOGIST 0149-1423 1558-9153 UNITED STATES English AAPS Journal SPRINGER 1550-7416 1550-7416 UNITED STATES English AAPS PHARMSCITECH SPRINGER 1530-9932 1530-9932 UNITED STATES English AATCC Journal of Research AMER ASSOC TEXTILE CHEMISTS COLORISTS-AATCC 2330-5517 2330-5517 UNITED STATES English AATCC REVIEW AMER ASSOC TEXTILE CHEMISTS COLORISTS-AATCC 1532-8813 1532-8813 UNITED STATES English Abdominal Radiology SPRINGER 2366-004X 2366-0058 UNITED STATES English ABHANDLUNGEN AUS DEM MATHEMATISCHEN SEMINAR DER UNIVERSITAT HAMBURG SPRINGER HEIDELBERG 0025-5858 1865-8784 GERMANY German ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY AMER CHEMICAL SOC 0065-7727 UNITED STATES English Academic Pediatrics ELSEVIER SCIENCE INC 1876-2859 1876-2867 UNITED STATES English Accountability in Research-Policies and Quality Assurance TAYLOR & FRANCIS LTD 0898-9621 1545-5815 UNITED STATES English Acoustics Australia SPRINGER 1839-2571 1839-2571 AUSTRALIA English Acta Bioethica UNIV CHILE, CENTRO INTERDISCIPLINARIO ESTUDIOS BIOETICA 1726-569X -
INTERDISCIPLINARY MATHEMATICAL SCIENCES (Mathematics), DST-Centre for Interdisciplinary Mathematical Sciences (CIMS), Institute of Science A
FORMAT FOR SUBJECTWISE IDENTIFYING JOURNALS BY THE UNIVERSITIES AND APPROVAL OF THE UGC {Under Clause 6.05 (1) of the University Grants Commission (Minimum Qualifications for appointment of Teacher and Other Academic Staff in Universities and Colleges and Measures for the Maintenance of Standards in Higher Education (4th Amendment), Regulations, 2016} Subject: INTERDISCIPLINARY MATHEMATICAL SCIENCES (Mathematics), DST-Centre for Interdisciplinary Mathematical Sciences (CIMS), Institute of Science A. Refereed Journals Sl. Name of the Journal Publisher and Year of Hard e-publication ISSN Number Peer / Indexing status. Impact Do you use Any other No. place of Start copies (Yes/No) Refree If indexed, Factor/Rating. any Information publication published Reviewed Name of the Name of the IF exclusion (Yes/No) (Yes/No) indexing data assigning agency. criteria for base Whether covered Research by Thompson & Journals Reuter (Yes/No) 1 2 3 4 5 6 7 8 9 10 11 1 Indiana University Mathematics Journal IUMJ 1952 Yes Yes 2 INFOR: Information Systems and U Toronto 2007 Yes Yes Operational Research 3 Insurance: Mathematics and Economics Science Direct 1982 Yes 0167-6687 Yes Yes 4 Integral Equations and Operator Theory Spinger 1978 Yes 1420-8989 Yes Yes 5 International Applied Mechanics Spinger 1966 Yes 1063-7095 Yes No 6 International Game Theory Review (IGTR) World Sci 1999 Yes 0219-1989 Yes No 7 International Journal for Computational Taylor and Fransis 2005 Yes 1550-2287 Yes Methods in Engineering Science and Mechanics 8 International Journal of Advances in Spinger 2009 Yes 0975-0770 Yes Engineering Sciences and Applied Mathematics 9 International Journal of Algebra and World Sci 1991 Yes 0218-1967 Yes Computation (IJAC) 10 International Journal of Applied and Spinger 2015 Yes 2349-5103 Yes Computational Mathematics 11 International Journal of Bifurcation and World Sci 1991 Yes 0218-1274 Yes Yes Chaos (IJBC) Sl. -
The Genome of the Sparganosis Tapeworm Spirometra Erinaceieuropaei Isolated from the Biopsy of a Migrating Brain Lesion Bennett Et Al
The genome of the sparganosis tapeworm Spirometra erinaceieuropaei isolated from the biopsy of a migrating brain lesion Bennett et al. Bennett et al. Genome Biology 2014, 15:510 http://genomebiology.com/2014/15/11/510 Bennett et al. Genome Biology 2014, 15:510 http://genomebiology.com/2014/15/11/510 RESEARCH Open Access The genome of the sparganosis tapeworm Spirometra erinaceieuropaei isolated from the biopsy of a migrating brain lesion Hayley M Bennett1*, Hoi Ping Mok3, Effrossyni Gkrania-Klotsas3, Isheng J Tsai1,8, Eleanor J Stanley1,9, Nagui M Antoun4, Avril Coghlan1, Bhavana Harsha1, Alessandra Traini1, Diogo M Ribeiro1, Sascha Steinbiss1, Sebastian B Lucas7, Kieren SJ Allinson2, Stephen J Price5, Thomas S Santarius5, Andrew J Carmichael3, Peter L Chiodini6, Nancy Holroyd1, Andrew F Dean2† and Matthew Berriman1† Abstract Background: Sparganosis is an infection with a larval Diphyllobothriidea tapeworm. From a rare cerebral case presented at a clinic in the UK, DNA was recovered from a biopsy sample and used to determine the causative species as Spirometra erinaceieuropaei through sequencing of the cox1 gene. From the same DNA, we have produced a draft genome, the first of its kind for this species, and used it to perform a comparative genomics analysis and to investigate known and potential tapeworm drug targets in this tapeworm. Results: The1.26GbdraftgenomeofS. erinaceieuropaei is currently the largest reported for any flatworm. Through investigation of β-tubulin genes, we predict that S. erinaceieuropaei larvae are insensitive to the tapeworm drug albendazole. We find that many putative tapeworm drug targets are also present in S. erinaceieuropaei, allowing possible cross application of new drugs. -
Web of Science® Science Citation Index Expandedtm 2012 March Web of Science®
REUTERS/Morteza Nikoubazl SOURCE PUBLICATION LIST FOR WEB OF SCIENCE® SCIENCE CITATION INDEX EXPANDEDTM 2012 MARCH WEB OF SCIENCE® - TITLE ISSN E-ISSN COUNTRY PUBLISHER 4OR-A Quarterly Journal of Operations Research 1619-4500 1614-2411 GERMANY SPRINGER HEIDELBERG AAPG BULLETIN 0149-1423 UNITED STATES AMER ASSOC PETROLEUM GEOLOGIST AAPS Journal 1550-7416 1550-7416 UNITED STATES SPRINGER AAPS PHARMSCITECH 1530-9932 1530-9932 UNITED STATES SPRINGER AMER ASSOC TEXTILE CHEMISTS AATCC REVIEW 1532-8813 UNITED STATES COLORISTS Abstract and Applied Analysis 1085-3375 1687-0409 UNITED STATES HINDAWI PUBLISHING CORPORATION ABDOMINAL IMAGING 0942-8925 1432-0509 UNITED STATES SPRINGER ABHANDLUNGEN AUS DEM MATHEMATISCHEN SEMINAR DER 0025-5858 1865-8784 GERMANY SPRINGER HEIDELBERG UNIVERSITAT HAMBURG ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL 0065-7727 UNITED STATES AMER CHEMICAL SOC SOCIETY Academic Pediatrics 1876-2859 1876-2867 UNITED STATES ELSEVIER SCIENCE INC Accountability in Research-Policies and Quality Assurance 0898-9621 1545-5815 UNITED STATES TAYLOR & FRANCIS LTD Acoustics Australia 0814-6039 AUSTRALIA AUSTRALIAN ACOUSTICAL SOC UNIV CHILE, CENTRO INTERDISCIPLINARIO Acta Bioethica 0717-5906 1726-569X CHILE ESTUDIOS BIOETICA Acta Biomaterialia 1742-7061 1878-7568 ENGLAND ELSEVIER SCI LTD Acta Botanica Brasilica 0102-3306 1677-941X BRAZIL SOC BOTANICA BRASIL Acta Botanica Mexicana 0187-7151 MEXICO INST ECOLOGIA AC Acta Cardiologica Sinica 1011-6842 TAIWAN TAIWAN SOC CARDIOLOGY Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca