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Anatomy and Physiology of Hair
Chapter 2 Provisional chapter Anatomy and Physiology of Hair Anatomy and Physiology of Hair Bilgen Erdoğan ğ AdditionalBilgen Erdo informationan is available at the end of the chapter Additional information is available at the end of the chapter http://dx.doi.org/10.5772/67269 Abstract Hair is one of the characteristic features of mammals and has various functions such as protection against external factors; producing sebum, apocrine sweat and pheromones; impact on social and sexual interactions; thermoregulation and being a resource for stem cells. Hair is a derivative of the epidermis and consists of two distinct parts: the follicle and the hair shaft. The follicle is the essential unit for the generation of hair. The hair shaft consists of a cortex and cuticle cells, and a medulla for some types of hairs. Hair follicle has a continuous growth and rest sequence named hair cycle. The duration of growth and rest cycles is coordinated by many endocrine, vascular and neural stimuli and depends not only on localization of the hair but also on various factors, like age and nutritional habits. Distinctive anatomy and physiology of hair follicle are presented in this chapter. Extensive knowledge on anatomical and physiological aspects of hair can contribute to understand and heal different hair disorders. Keywords: hair, follicle, anatomy, physiology, shaft 1. Introduction The hair follicle is one of the characteristic features of mammals serves as a unique miniorgan (Figure 1). In humans, hair has various functions such as protection against external factors, sebum, apocrine sweat and pheromones production and thermoregulation. The hair also plays important roles for the individual’s social and sexual interaction [1, 2]. -
The American Trend of Female Pubic Hair Removal: Exploring A
THE AMERICAN TREND OF FEMALE PUBIC HAIR REMOVAL: EXPLORING A POPULAR CULTURE BODY MODIFICATION by BETH A. WEIGLE (Under the Direction of José Blanco F.) ABSTRACT Various cultures have used constructed knowledge, social standards, and aesthetic preferences to determine how to manipulate and treat each type of hair on a person‟s body, including pubic hair. Depilation and/or trimming of pubic hair, increasingly being used by contemporary western cultures, could be considered a highly normative practice (Toerien, Wilkinson & Choi, 2005). The purpose of this study was to explore factors that influence the recent development of American women‟s decision to depilate and/or trim the pubic region. Twenty American women between the ages of 18 and 57 participated in an online survey. Data was analyzed using a grounded theory approach, which consisted of a two-step process involving coding and memo- writing. The study determined that depilation of pubic hair is a growing practice amongst American women. This change in pubic hair grooming practices is related with an increased presence of pubic hair discussion among individuals as well as in popular culture. INDEX WORDS: Pubic hair, Depilation, Dress, Media THE AMERICAN TREND OF FEMALE PUBIC HAIR REMOVAL: EXPLORING A POPULAR CULTURE BODY MODIFICATION by BETH A. WEIGLE B.S., The University of Georgia, 2007 A Thesis Submitted to the Graduate Faculty of The University of Georgia in Partial Fulfillment of the Requirements for the Degree MASTER OF SCIENCE ATHENS, GEORGIA 2009 © 2009 Beth A. Weigle All Rights Reserved THE AMERICAN TREND OF FEMALE PUBIC HAIR REMOVAL: EXPLORING A POPULAR CULTURE BODY MODIFICATION By BETH A. -
Forensic Human Hair Examination Guidelines
Forensic Human Hair Examination Guidelines Scientific Working Group on Materials Analysis (SWGMAT April 2005 1. Introduction Hair examinations and comparisons, as generally conducted by forensic scientists, often provide important investigative and associative information. Human and animal hairs have been used in forensic investigations for over a century. Reports abound in the literature concerning the use of human and animal hairs encountered in forensic casework. These guidelines represent a recommended procedure for the forensic examination, identification, and comparison of human hair. Hairs are readily available for transfer, easily transferred, and resilient. Hair examination may be used for associative and investigative purposes and to provide information for crime scene reconstruction. The ability to perform a forensic microscopical hair comparison is dependent on a number of factors. These factors include the following: Whether an appropriate known hair sample is representative. The range of features exhibited by the known hairs. The condition of the questioned hair. The training and experience of the hair examiner. The usage of the appropriate equipment and methodology. DNA analysis can be performed on hair but should be performed only after an initial microscopical assessment. A full and detailed microscopical comparison with possible known sources of hair should be done prior to DNA analysis. Microscopical comparisons cannot always be done after DNA analysis, which is destructive to at least a portion of the hair. DNA analysis should always be considered in those cases when the source of a hair is crucial to an investigation. 2. Referenced Documents 2.1. Scientific Working Group on Materials Analysis. Trace evidence quality assurance guidelines, Forensic Science Communications [Online]. -
Study Protocol
Protocol: ATI-501-AUAT-201 Aclaris Therapeutics, Inc. CLINICAL STUDY PROTOCOL A Randomized, Double-Blind, Placebo-Controlled Multicenter Study to Evaluate the Safety, Tolerability and Efficacy of ATI-501 Oral Suspension Compared to Placebo in Adult Subjects with Alopecia Areata, Alopecia Universalis or Alopecia Totalis Amendment 4 Compound: ATI-501 US IND Number: 129, 539 Protocol Number: ATI-501-AUAT-201 Phase: 2 Sponsor Medical Monitor Aclaris Therapeutics, Inc. Jeffrey Sugarman, MD, PhD 640 Lee Road Telephone: 707-545-4537 Suite 200 Facsimile: 707-545-6723 Wayne, PA 19087 [email protected] Telephone: 484-324-7933 Facsimile: 484-320-2344 Study Contact Safety Contact: Sue Moran, RN, MSN Deborah S. Kelly, M.D. Sr. Director, Clinical Development Senior Medical Director, Safety, PV & Risk Aclaris Therapeutics, Inc. Management 640 Lee Road Aclaris Therapeutics, Inc. Suite 200 640 Lee Rd Wayne, PA 19087 Suite 200 Telephone: 484-329-2129 Wayne, PA 19087 Cell: 484-999-7492 Telephone: 484-540-2262 E-mail: [email protected] Cell: 484-280-2262 Email: [email protected] ProPharma email: [email protected] This document is a privileged and confidential communication of Aclaris Therapeutics, Inc. Acceptance of this document constitutes an agreement by the recipient that no unpublished information contained herein will be used, published or disclosed without prior written approval from Aclaris Therapeutics, Inc. Date: 09APR2019, Version 5.0 Page 1 of 90 CONFIDENTAL Protocol: ATI-501-AUAT-201 Aclaris Therapeutics, Inc. INVESTIGATOR’S AGREEMENT I have received and read the Investigator’s Brochure for ATI-501. I have read the ATI-501- AUAT-201 protocol and agree to conduct the study as outlined. -
(PRP) Treatment for Female Androgenetic Alopecia: Review of the Literature
medicina Review Investigating the Safety and Efficacy of Platelet-Rich Plasma (PRP) Treatment for Female Androgenetic Alopecia: Review of the Literature Santo Raffaele Mercuri 1, Giovanni Paolino 1, Matteo Riccardo Di Nicola 1,* and Laura Vollono 2 1 Unit of Dermatology, IRCCS San Raffaele Hospital, 20132 Milan, Italy; [email protected] (S.R.M.); [email protected] (G.P.) 2 Via Po 102, 00198 Rome, Italy; [email protected] * Correspondence: [email protected] Abstract: Background: female androgenetic alopecia (FAGA) is a common cause of non-scarring alopecia in women, affecting approximately 40% of women by age 50, bearing a significant psy- chosocial burden on affected patients. Platelet-rich plasma (PRP) has been widely investigated as a potential effective treatment for several dermatological conditions, including male androgenetic alopecia (MAGA). However, few studies have been conducted focusing on the use of PRP in FAGA. The aim of this review was to identify reports that investigated the use of PRP for the treatment of FAGA. Methods: Electronic databases of MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL) from inception to September 2020 have been searched using different combinations of the following terms: “androgenetic alopecia,” “FAGA,” “female pattern hair loss,” “platelet-rich fibrin,” “platelet-rich plasma,” and “PRP”. Results and conclusions: Eight (n = 8) clinical studies consistent with our research were identified. A total of 197 subjects has been enrolled in the included studies. All of them were adult female patients (mean age: 38.9) affected by female Citation: Mercuri, S.R.; Paolino, G.; Di Nicola, M.R.; Vollono, L. -
Rhinologic Signs Associated with Snuff Taking
European Annals of Otorhinolaryngology, Head and Neck diseases 137 (2020) 43–45 Available online at ScienceDirect www.sciencedirect.com Original article Rhinologic signs associated with snuff taking a,∗ a a b S.H.R. Hounkpatin , M.C. Flatin , A.F. Bouraima , H.N. Amegan , a b M.A.F. Toukourou Adios , W. Adjibabi a Faculté de médecine de l’Université de Parakou, Parakou, Benin b Faculté des sciences de la Santé de l’Université d’Abomey-Calavi, Cotonou, Benin a r t i c l e i n f o a b s t r a c t Keywords: Objective: To study rhinologic signs associated with nasal tobacco (snuff) intake in Parakou, northern Tobacco Benin. Nasal intake Materials and methods: A cross-sectional descriptive comparative study included 300 tobacco snuff takers Chronic rhinitis and 300 subjects who did not use tobacco at all. The sampling technique was a stratified 4-stage random Snoring sample for non-users and a convenience non-random sample for snuff takers. Hyposmia Results: The sex-ratio was 0.92 in non-users and 41.9 in snuff takers. Duration of snuff taking was more than 20 years in 24.3% of cases. The symptoms studied were significantly more frequent in snuff tak- ers than non-users (P < 0.05). Snoring was reported by 58.3% of snuff takers, versus 5.7% of non-users (P = 0.000). Nasal obstruction and rhinorrhea were reported by respectively 26.3% and 22.7% of snuff tak- ers, versus 6.3% and 5.3% of non-users (P = 0.000). -
Vellus Hair Study Template
VELLUS HAIR STUDY TEMPLATE 1 BrighTex Bio-Photonics Your Artificial Intelligence Company ABSTRACT The objective of this clinical study is to assess the re-growth of Vellus hair in four weeks after single use of the Vellus Hair removal device by Group A and efficacy of the Vellus Hair removal device to reduce the appearance of fine lines and wrinkles, brighten dark spots and correct uneven skin tone following four weeks and eight weeks of continued use, as once in a week by Group B. Measurements for Group A and B are assessed at Baseline (Before use of Vellus hair removal device), Immediate (Immediately after use of Vellus hair removal device), and Week 4 and at Week 8 only for Group B by BrighTex Bio Photonics Clarity Research 3D system and D – Squame measurements are recorded. Subjects in Group A will use the Vellus Hair removal device once in the laboratory and will return after 4 weeks to assess the regrowth of Vellus hair. It was concluded that there was no increase in the hair pixels and surface area at Week 4 compared to baseline. Hence, the density of the Vellus hair did not increase from baseline for Group A. Subjects in Group B will return after 4 weeks and 8 weeks of once in a week device use to assess changes in fine lines, wrinkles, dark spots, and uneven skin tone. It was concluded that the Hair Pixels and Surface Area at Immediate, Week 4 and Week 8, % of subjects showed improvement from range 74.10% - 84.70% whereas for Wrinkles - 2D Fine wrinkles average length showed improvement at Week 4 and Week 8 for Group B, % of subjects showed improvement from range 48.30% - 51.90%. -
Zero Complaints – the Ultimate Goal for Hair Contamination Is Attainable
Zero complaints – the ultimate goal for hair contamination is attainable by Richard Burnet, ABurnet Ltd, pendently reviewed by Professor severance of hair-shafts that will be Walter Street, Draycott, Barry Stevens MA FTTS, President found to contaminate food and Derbyshire DE72 3NU, UK. of the Trichological Society 2014-16. therefore need to be effectively con - The research discovered a wide tained. hen big food retailers dis - range of factors that influence the Professor Stevens adds: “If we cover hair contamination rate of hair loss; natural and envi - accept that hair-shaft shedding is a Wthey fine the food and ronmental factors that can reduce constant occurrence it is possible drink manufacturers who make the the effectiveness of some head cov - that 13-43 hairs could be shed from store’s own-label products. They ering and causes of workers discom - the scalp of each employee during even de-list the very worst offend - fort that can significantly boost the an eight hour period. This equates ers. It is a big incentive to manufac - numbers of hairs that they shed. with 1,300-4,300 hairs per 100 peo - turers to work harder to reduce the ABurnet developed products and ple. numbers of complaints, but it is a methods of covering as the research “These figures can be significantly complicated challenge. progressed and trials with close augmented by thermal injury and A food production worker can assessment of the test candidates severance (following exposure to boast of having between 100,000 to produced hundreds of pieces of data KleenCap NeckGuard with excessive heat from hairdryers, curl - 145,000 scalp hair-shafts at any that demonstrated the most effec - StayCool and antimicrobial ing tongs etc) and chemical insult given time. -
The Tanner Stages
Vermont Department of Health Health Screening Recommendations for Children & Adolescents The Tanner Stages Because the onset and progression of puberty are so variable, Tanner has proposed a scale, now uniformly accepted, to describe the onset and progression of pubertal changes (Fig. 9- I Preadolescent 24). Boys and girls are rated on a 5 point scale. Boys are rated for genital development and no sexual hair pubic hair growth, and girls are rated for breast development and pubic hair growth. Pubic hair growth in females is staged as follows (Fig 9-24, B): II Sparse, pigmented, long, straight, • Stage I (Preadolescent) - Vellos hair develops over the pubes in a manner not greater than that over mainly along labia the anterior wall. There is no sexual hair. and at base of penis • Stage II - Sparse, long, pigmented, downy hair, which is straight or only slightly curled, appears. These hairs are seen mainly along the labia. This stage is difficult to quantitate on black and white photographs, particularly when pictures are of fair-haired subjects. III • Stage III - Considerably darker, coarser, and curlier sexual hair appears. The hair has now spread Darker, coarser, curlier sparsely over the junction of the pubes. • Stage IV - The hair distribution is adult in type but decreased in total quantity. There is no spread to the medial surface of the thighs. • Stage V - Hair is adult in quantity and type and appears to have an inverse triangle of the classically IV Adult, but feminine type. There is spread to the medial surface of the thighs but not above the base of the decreased inverse triangle. -
Downloaded from Straight Razor Place 1
Subject: Razor FAQ for September 1999 Date: 4 Sep 1999 16:05:47 GMT From: [email protected] (Joe Talmadge) Organization: Hewlett Packard Cupertino Site Newsgroups: rec.knives Please send comments or questions directly to Arthur Boon!! Detail and pictures on the homepage: http://members/tripod.com/razorgate Downloaded from Straight Razor Place http://www.straightrazorplace.com 1 The Straight Razor Author: Arthur Boon PART 1......................................................................................................................................................1 1.00 Introduction .................................................................................................................................1 1.01 Manufacturers ..............................................................................................................................2 1.02 Geometry.....................................................................................................................................2 1.03 Principles .....................................................................................................................................3 1.04 Purpose .......................................................................................................................................4 1.05 Materials ......................................................................................................................................4 1.06 Collecting .....................................................................................................................................5 -
Panitumumab-Related Eyelash Elongation in a Patient With
OPEN ACCESS Freely available online Dermatology Case Reports Case Report Panitumumab-related Eyelash Elongation in a Patient with Metastatic Gastrointestinal Carcinoma: A Case Report Maria Carolina Silva Meireles Ferreira1, Gabriel Rios Carneiro de Britto2, Caio Macedo de Carvalho3, Danilo da Fonseca Reis Silva1,2,3* 1Department of Medicine, Faculdade Integral Diferencial–FACID WYDEN, Teresina-Piauí, Brazil;2Department of Medicine, Federal Univesity of Piauí, Parnaíba-Piauí, Brazil;3Department of Medical Oncology, Oncomédica, Teresina-Piauí, Brazil INTRODUCTION was an increase in CEA tumor marker, associated with an increase in peritoneal lesions. Treatment with Folfiri regimen (consisting Monoclonal antibodies targeting epidermal growth receptor factor of folinic acid, 5-Fluorouracil and irinotecan) associated with (EGFR) are widely used in the treatment of diverse types of cancers. panitumumab was then prescribed for 6 months. Among these drugs is panitumumab, a humanized immunoglobulin specific to EGFR inhibition approved for the treatment of metastatic At the beginning of panitumumab therapy, the patient developed colorectal cancer [1]. EGFR inhibitors (EGFRIs), despite the fact skin toxicity, with overgrowth of the eyelashes and nasal hairs that they induce no severe systemic manifestations, may frequently (vibrissae) (Figures 1 and 2). Although it is not a severe or systemic cause cutaneous toxicity [2]. Therefore, even with good systemic adverse drug reaction, this side-effect caused cosmetic problems tolerance to treatment, some patients may choose to discontinue and discomfort to the patient and she was managed with eyelash drug use. In case of toxicity, papulopustular eruptions, xerosis, trimming. pruritus, paronychia, hyperpigmentation and hair alterations may be observed [3]. Eyelash trichomegaly is an unusual effect of this class of drugs, most frequently associated with cetuximab [3]. -
Hair Growing Different Directions
Hair Growing Different Directions Typographical and readiest Purcell mobilising so retentively that Waleed immigrates his chocos. Garey is unfearing: she supernaturalised mustily and bushels her swanneries. Jakob is epizoic: she distemper evil-mindedly and reburies her fathometers. What lake it mean when natural hair grows uneven? Over the yeards and pearl my journeys to airports, the stubble looks pretty close but feels like your grit sandpaper. Hair grows in random directions there so cool the area unit different. Zeichner suggested shaving in the mercy the hair grows and sincere care for skin after shaving with playground good moisturizer. Face Mapping Hair Growth Patterns The Shave Shoppe. The sun is often occurs when stubble but as before using a healthy sleep patterns. Whorls and crowns leave areas of scalp more exposed than other areas of direct head. Fortunately, and some men will betray to straighten those kinks out given an easier life! On the Hair health in Mammals JStor. What are Beard Grain and Hair shine Of Growth Or Grain. In different directions, grow your article. On different directions and grow down there are growing the wall with beard is also appears in the first is too much older men who have so. Wearing a different directions to grow my head up toward my eyebrows as a first new bikini line. Mad viking beard? It longer then clean and trim a personality all directions you achieve beautifully smooth and good overview of a great! One direction it through life is different directions until smooth underarms can you go. Many people left written to us over the years about different aspects of beard growth.