BULLETIN OF MEDICAL SCIENCE 4 (8) 2017

UDC 613.31:543.3:351.77 (571.15) THE ASSESSMENT OF RISK OF DRINKABLE WATER CHEMICAL POLLUTION TO THE HEALTH OF POPULATION Center of hygiene and epidemiology in Altai Krai, T.I. Gubareva, A. Yu. La, Yu.A. Kapayeva, L.A. Skripkina, N.Ye. Soldatova

There was performed the hygienic assessment of the level of drinkable water chemical pollution on the territory of Altai Krai and revealed the most troubled territories consuming chemically polluted drinkable water. The data obtained by means of social-hygienic monitoring allowed to adjust the plan of monitoring laboratory tests of drinkable water of centralized water supply systems in populated areas. Key words: social-hygienic monitoring, drinkable water, chemical substances, troubled territories.

Water is an essential element of the environ- populated areas, the amount of population under ment having a significant impact on human health studies equaled to 440 019 persons. The studies and activity, it is the basis for origin and mainte- for the presence of lead, cadmium and arsenic were nance of all life. Providing the population with conducted at 4 districts of Altai Krai at 4 populat- drinkable water of satisfactory quality is one ed areas, the amount of population under studies of the main social-hygienic issues. Drinkable wa- equaled to 189 810 persons, making 9.0 per cent ter should be safe in epidemiological and radia- of the total amount of population using central- tion respect, harmless in chemical composition ized utility and drinking water supply. The stud- and should have favourable organoleptic proper- ies for the presence of lead, cadmium, arsenic ties. It is believed that up to 80 per cent of all chem- and chromium (6+) were conducted at the town ical compounds entering the outside environment of , the amount of population under study sooner or later get into natural water with industri- equaled to 28 372 persons. All studies were per- al, household and storm drains. Numerous stud- formed by accredited laboratories with the use ies have established that drinkable water anthro- of standardized analytical methods. Assessment pogenic pollution along with other environmental of risk was carried out in accordance with the pro- factors is an intensive factor of impact on human visions of P 2.1.10.1920-4 “Human Health Risk As- health. sessment from Environmental Chemicals”.

Objective Results and discussion To conduct a hygienic assessment of the level It was established that four groups were regis- of drinkable water chemical pollution on the terri- tered in the analysis of sanitary-chemical parame- tory of Altai Krai to reveal the most troubled terri- ters of controlled substances. tories and amount of population consuming chem- The first group is for substances of hazard class- ically polluted drinkable water. es 1 and 2 (arsenic, lead, boron, nickel, nitrites) with concentration exceeding 1 TLV. This group Materials and methods includes 7 territories of Altai Krai: Pervomaysky, In 2016, 34 902 studies with a multiplici- Khabarsky, Rebrikhinsky, Pavlovsky, Shipun- ty of 12 samples per year were conducted at 372 ovsky, Kamensky Districts, the city of Barnaul. monitoring points on the distribution network The second group is for substances of hazard class of centralized utility and drinking water sup- 3 (iron, manganese, magnesium, nitrates, chlorine) ply systems within the framework of social-hy- with concentration exceeding from 1 to 2 TLV. gienic monitoring system in Altai Krai. To assess This group includes 19 territories: Ust-Kalmansky, the direct influence of the quality of drinkable wa- Troitsky, Topchikhinsky, Talmensky, Tabunsky, ter on population health, on administrative terri- Rebrikhinsky, Pankrushikhinsky, Kulundinsky, tories of Altai Krai, a calculation and population Krasnoshchyokovsky, Kalmansky, Kuryinsky, health risk assessment (the assessment of the prob- Bystroistoksky, Altaysky, Aleysky, Loktevsky, ability of developing a threat to a person’s or fu- Zavyalovsky Districts, the city of , ture generations’ life or health) was carried out, the towns of , Aleysk. this risk being preconditioned by drinkable water The third group is for substances of hazard class chemical pollution. In this study, the assessment 3 (iron, manganese, nitrates) with concentration ex- of risk was based on average annual chemical ceeding from 2 to 5 TLV. This group includes 10 ter- substances concentrations on the distribution net- ritories: Romanovsky, Novichikhinsky, Nemetsky work. The studies of drinkable water on distribu- National, Yeltsovsky, Burlinsky, Kosikhinsky, tion network for the presence of lead and cadmium Shelabolikhinsky Districts, the towns of Novoal- were conducted at 11 districts of Altai Krai at 18 taysk, Kamen-na-Obi, . 14 BULLETIN OF MEDICAL SCIENCE 4 (8) 2017

The fourth group is for substances of hazard class to non-carcinogenic risk in child population is due 3 (nitrates, iron, manganese) with concentration to the receipt of nitrates and fluorine. exceeding 5 TLV. This group includes 26 territo- In the case of simultaneous receipt of chemical ries: Shipunovsky, Khabarsky, Tyumentsevsky, substances with drinkable water the following crit- Suyetsky, Soltonsky, Soloneshensky, Sovetsky, ical organs are identified among adults and chil- Smolensky, Rubtsovsky, Pospelikhinsky, Pavlov- dren: blood and blood-forming organs, cardiovas- sky, Mamontovsky, Krutikhinsky, Krasnogorsky, cular system, skeletal system and teeth, immune Kamensky, Zonalny, Zarinsky, Tselinny, Za- system, central nervous system, hormone system, lesovsky, Yegoryevsky, Blagoveshchensky, Biysky, reproductive system, morphosis, liver, kidneys, Pervomaysky Districts, the town of , the cit- skin and mucous membranes, gastrointestinal tract. ies of and Barnaul. Total risk indices in case of simultaneous chemical No exceedance of concentration of above men- substances receipt in their impact on critical organs tioned substances was found in populated areas and systems in adult population exceed permissi- of Bayevsky, Volchikhinsky, Zmeinogorsky, Kly- ble values in the influence on blood and cardiovas- uchevsky, Kytmanovsky, Mikhaylovsky, Pet- cular system in Rubtsovsky, Nemetsky National ropavlovsky, Rodinsky, Slavgorodsky, Togulsky, Districts. In child population (from 6 to 18 years), Tretyakovsky, Uglovsky, Ust-Pristansky, Chary- total risk indices exceed the permissive value (>1) shsky Districts and the town of . for blood and blood-forming organs, cardiovas- The total individual carcinogenic risk due cular system in Rubtsovsky, Nemetsky Nation- to peroral route of lead, cadmium, arsenic with al and Loktevsky Districts. For child population drinkable water is within permitted limits. (from 0 to 6 years), total risk indices exceed the per- The individual carcinogenic risk at the town missive value (>1) for blood and blood-forming of , and Novichikhinsky, Talmensky, organs, cardiovascular system in Altaysky, Yego- Troitsky, Shipunovsky Districts is up to the first ryevsky, Zmeinogorsky, Krasnoshchyokovsky, Loktevsky, Mamontovsky, Nemetsky National, range (the individual risk throughout life is equal Rubtsovsky, Tretyakovsky Districts; for skeletal to or less than 1x10-6). The individual carcinogenic system in Kamensky, Pavlovsky, Slavgorodsky, risk at the town of Zmeinogorsk, and Petropavlov- Tyumentsevsky, Khabarsky, Shelabolikhinsky Dis- sky, Kamensky, Krutikhinsky, Kuryinsky, Pervo- tricts. maysky, Tretyakovsky, Krasnoshchyokovsky, Pos- pelikhinsky, Loktevsky Districts is up to the second Conclusions range (the individual risk throughout life is more The results obtained make it possible to con- than 1x10-6, but less than 1x10-4). clude that: Non-carcinogenic risks were estimated in 78.1 1. In Altai Krai the levels of total carcinogenic risk per cent of Altai Krai population using central- from lead, cadmium, arsenic, chromium (6+) are ized drinking water supply. The number of people within permitted limits. who underwent the assessment of risk of non-car- The individual carcinogenic risk at the town cinogenic effects was 1,653,826. As a consequence of Novoaltaysk, and Novichikhinsky, Talmensky, of drinkable water use in Altai Krai, the level Troitsky, Shipunovsky Districts is up to the first of non-carcinogenic risk from chemical substanc- range of risk (the individual risk throughout life es in adult population exceeds the permitted value is equal to or less than 1x10-6), these risk levels does (HQ>1) in Rubtsovsky, Nemetsky National Dis- not require additional measures, but are subject tricts. The contribution to non-carcinogenic risk to periodic monitoring. in adult population is due to the receipt of nitrates The individual carcinogenic risk at the town from 71.4 per cent in Nemetsky National District of Zmeinogorsk, and Petropavlovsky, Kamensky, to 91 per cent in Rubtsovsky District. Krutikhinsky, Kuryinsky, Pervomaysky, Tretya- The level of non-carcinogenic risk from sub- kovsky, Krasnoshchyokovsky, Pospelikhinsky, stances in child population (from 6 to 18 years) ex- Loktevsky Districts is up to the second range ceeds the permitted value (HQ>1) in Rubtsovsky, of risk (the individual risk throughout life is more Nemetsky National, Loktevsky Districts. The con- than 1x10-6, but less than 1x10-4). These levels are tribution to non-carcinogenic risk in is due to the re- subject to constant monitoring. ceipt of nitrates from 70 per cent in Nemetsky Na- 2. The levels of non-carcinogenic risk in adult pop- tional District to 89.2 per cent in Rubtsovsky ulation exceed the permitted value (HQ>1) for ni- District. The level of non-carcinogenic risk in child trates in Rubtsovsky, Nemetsky National Districts. population (from 0 to 6 years) exceeds the permit- Children are less resistant to influence of chemical ted value (HQ>1) in Kamensky, Tyumentsevsky, pollutions of environmental objects, which include Shelabolikhinsky, Altaysky, Yegoryevsky, Zmei- drinkable water. The level of non-carcinogenic risk nogorsky, Krasnoshchyokovsky, Loktevsky, in child population (from 6 to 18 years) from chem- Mamontovsky, Nemetsky National, Rubtsovsky, ical substances exceeds the permitted value (HQ>1) Tretyakovsky Districts. The main contribution for nitrates in Rubtsovsky, Nemetsky National, 15 BULLETIN OF MEDICAL SCIENCE 4 (8) 2017

Loktevsky Districts. In child population (from 0 Tretyakovsky Districts; for skeletal system to 6 years), the level of non-carcinogenic risks from in Kamensky, Pavlovsky, Slavgorodsky, Tyument- substances exceeds the permitted value (HQ>1) sevsky, Khabarsky, Shelabolikhinsky Districts. for nitrates and fluorine in Kamensky, Tyument- 5. This information material is appropriate sevsky, Shelabolikhinsky, Altaysky, Yegoryevsky, for use when planning laboratory studies of drink- Zmeinogorsky, Krasnoshchyokovsky, Loktevsky, able water in a distribution network in popula- Mamontovsky, Nemetsky National, Rubtsovsky, tion centres and making management decisions Tretyakovsky Districts and are estimated as elevat- through the Federal Law No 294-FZ of December ed. 26, 2008 (as amended by the Federal Law No 277- 3. Total risk indices in case of simultaneous FZ of July 3, 2016). chemical substances receipt in their impact on crit- Thus, the data of social-hygienic monitoring ical organs and systems in adult population exceed made it possible to numerically assess the negative permissible values in the influence on blood and car- impact on health due to drinkable water from cen- diovascular system in Rubtsovsky, Nemetsky Na- tralized systems in Altai Krai, to identify troubled tional Districts. territories, and also to adjust the plan of monitor- 4. In child population (from 6 to 18 years), to- ing laboratory tests of drinkable water of central- tal risk indices exceed the permissive value (>1) ized water supply systems in population centres. for blood and blood-forming organs, cardiovas- cular system in Rubtsovsky, Nemetsky National, Contacts Loktevsky Districts. For child population (from 0 Corresponding author: Gubareva Tatyana Iva- to 6 years), total risk indices exceed the permissive novna, Chief Physician of the Center of hygiene value (>1) for blood and blood-forming organs, and epidemiology in Altai Krai, Barnaul. cardiovascular system in Altaysky, Yegoryevsky, 656043, Barnaul, per. Radishcheva. 50. Zmeinogorsky, Krasnoshchyokovsky, Loktevsky, Tel.: (3852) 353993. Mamontovsky, Nemetsky National, Rubtsovsky, E-mail: [email protected]

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