Germany & Austria New England Biolabs GmbH

Brüningstr. 50, Geb B852 Cover: NEB’s 140,000 square foot laboratory facility located in Ipswich, MA. 65926 Frankfurt/Main, Content is covered by one or more patents, trademarks and/ Tel: +49/(0)69/305-23140 or copyrights owned or controlled by New England Biolabs, About Fax: +49/(0)69/305-23149 Inc. However, its use may require you to obtain additional third party intellectual property rights for certain applications. For more Free Call: 0800/246 5227 (Germany) information, please email us at [email protected]. Free Call: 00800/246 52277 (Austria) LEED® is a registered trademark of the Green Building Council. [email protected] SOLAR AQUATICS SYSTEM™ is a trademark of the Ecological New England Biolabs www.neb-online.de Engineering Group. New England Biolabs France SAS Genopole Campus 1, Bâtiment 6 5 rue Henri Desbruères 91030 Evry cedex, France Tel.: 0800 100 632 (Customer Service) Tel.: 0800 100 633 (Technical Service) FAX.: 0800 100 610 [email protected] www.neb-online.fr

Headquarters: USA New England Biolabs, Inc. Telephone: (978) 927-5054 Toll Free (USA Orders): 1-800-632-5227 Toll Free (USA Tech): 1-800-632-7799 Fax: (978) 921-1350 [email protected] www.neb.com www.neb.com

Distributors For a complete list of all NEB subsidiaries and ­distributors, please go to: www.neb.com/international-support * “GMP-grade” is a branding term NEB uses to describe reagents manufactured at NEB’s Rowley facility. The Rowley facility was designed to manufacture reagents under more rigorous infrastructure and process controls to achieve more stringent product specifications and customer requirements. Reagents manufactured at NEB’s Rowley facility are manufactured in compliance with ISO 9001 and ISO 13485 quality management system standards. However, at this time, NEB does not manufacture or sell products known as Active Pharmaceutical Ingredients (APIs), nor does NEB manufacture its products in compliance with all of the Current Good Manufacturing Practice regulations.

ISO 9001 ISO 14001 ISO 13485 Registered Registered Registered Quality Environmental Medical Devices NEB’s service hub for customers in Germany, Management Management Austria and Central is located in Frankfurt/Main (Germany). www.neb-online.de

About_NEB v2_DE – 4/20 x/yNEB140 Environmental Stewardship OEM & Customized Products We continuously strive to promote sound ecological There are multiple considerations when selecting a reagent practices and environmental sustainability in order to protect partner for your custom needs – technical expertise, our natural resources, both locally and globally. Further, it is scale, turnaround time, quality, and logistical support are our goal to continuously improve our business processes in all critical to meeting your goals. And if you are working order to minimize our impact on the environment. in a regulated market, that list of concerns and hurdles Established in 1974 by Donald G. Comb, New England Biolabs® is proud to be recognized as a world leader in the discovery, increases considerably. At NEB, we have taken these factors production and supply of reagents for the life science industry. For over 45 years, NEB has been shaping the landscape of bioscience Believing it possible to conduct cutting-edge research into account and can provide you with a unique solution research through the discovery and development of superior research reagents and technical support. From our founding principles – and production in a greener, less environmentally that allows you to access novel products, meet quality placing the advancement of science and the stewardship of the environment as our highest priorities – to our unique corporate culture, impactful way, NEB is headquartered in a modern, specifications, speed time to market, and ultimately streamline NEB’s philosophy can be distilled down to three core values: passion, humility and being genuine. LEED® certified (Leadership in Energy and Environmental your supply chain – leaving you more time for innovation. Design), 140,000 square foot building. Our state-of-the-art 140,000 square foot research and production facility, located in Ipswich, MA, includes a modern fermentation NEB has over 45 years of experience in the discovery, center and fully equipped laboratories for production, quality control, product development and basic research. To better serve the Most prominent in our conservation efforts is our development and manufacture of needs of customers in regulated markets, NEB opened a facility in Rowley, MA for the manufacturing of GMP-grade* materials. state-of-the-art Solar Aquatics System™. This system reagents. These are essential components in a vast array utilizes and accelerates the process found in streams and of genomic and proteomic technologies that continue wetlands to treat the campus’ wastewater, making it clean to transform our understanding of the world we live in, and technical support staff. NEB is happy to provide the enough to reuse for groundwater recharge. Advancement of Science and ultimately the diagnosis and treatment of disease. necessary technical assistance through the lifetime of NEB established the first shipping box recycling program We believe that basic research and the cultivation of Our Customized Solutions Team was purpose-built to the product. Our research staff, technical support and over 40 years ago, to divert polystyrene from landfills. scientific knowledge is critical for us to stay connected leverage what we do well. Our uniquely collaborative customer service teams, as well as accounting, sales and In addition, our extensive in-house recycling program with our customers and drive scientific breakthroughs. spirit, commitment to quality, scale of manufacturing and marketing are always available to help. includes paper, plastics, expanded polystyrene, glass, Over 30 labs participate in research projects, in exceptional technical and customer support all help to aluminum, batteries and electronics. areas that include epigenetics, glycobiology, RNA Our technical support model is unique as it utilizes most ensure the success of our partners. To learn more, visit biology, , protein expression, and of the scientists at NEB. Several of our product lines www.neb.com/CustomizedSolutions. characterization of DNA and RNA polymerases, ligases have designated technical support scientists assigned and modifying enzymes. to servicing customers in those application areas. Any product question could be dealt with by one of the Accessibility and Logistics Research scientists at NEB have authored or co-authored technical support scientists, the product manager who is New England Biolabs GmbH is the NEB service hub for over 1,200 research publications. Our research effort the scientist responsible for manufacturing the product, Central Europe. We are located at the Technology-Park is also aided by successful post-doctoral fellows and a product development scientist who helped develop the in Frankfurt-Höchst (Germany), enabling us to provide involvement in Masters and Ph.D. programs. product, or by a researcher who uses the product in their customized service beyond everyday experience. The daily research. As such, customers are supported by quality of our personalized services, as well as our Delivering the Highest Quality scientists and experts in the product or its application. ability to deliver high quality products with unsurpassed In Germany and Austria, NEB switched in 2019 from consistency, guarantee our customers and partners a Product & Support Humanitarianism “styrofoam” boxes to climate-neutral shippers made valuable advantage in their research activities. With a reliance on recombinant technologies, our of recycled cardboard. The NEB Eco-Box utilizes pure products are designed and manufactured in our At NEB, we see opportunities all around us to improve and thermally treated straw or hemp fibers in food International Network lives with science, and we are inspired by researchers ISO 13485:2016 and ISO 9001:2015 certified facility quality as insulation material. While 100% recyclable or NEB has extensive worldwide distribution through a who demonstrate how science can help push the in Ipswich, MA, USA. We are constantly improving the biodegradable, the box requires 50-times less primary network of exclusive distributors and agents, plus our social barometer to a kinder, more compassionate, and stringency and range of our quality controls, to ensure energy in production. wholly-owned subsidiaries located in , , healthier future. This philosophy lies behind NEB’s that our products will perform to your expectations For more details, visit www.neb-online.de/en/ , France, Germany, , and the longstanding commitment to its research every time. We recently expanded our manufacturing nachhaltigkeit-und-umweltschutz-bei-neb. United Kingdom. footprint by opening a facility for the production of program, which contributes to the understanding GMP-grade materials for customers requiring an and treatment of poorly funded and under-studied To learn more, visit www.neb.com/about-neb enhanced level of quality and support. neglected tropical diseases. NEB has also played a role in the establishment of several foundations devoted NEB’s commitment to a customer is the same, regardless to humanitarian efforts, including the New England of whether or not they are purchasing a product from us. Biolabs Foundation (NEBF.org) and the Creative Action Ongoing research is supported by our catalog, website Institute (CreativeActionInstitute.org).