CDC14B Antibody Cat. No.: 63-773

CDC14B Antibody

Flow cytometry analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat- anti-rabbit secondary antibodies were used for the analysis.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse

This CDC14B antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 188-215 amino acids from the Central region of human CDC14B.

TESTED APPLICATIONS: Flow, WB

For WB starting dilution is: 1:1000 APPLICATIONS: For FACS starting dilution is: 1:10~50

October 2, 2021 1 https://www.prosci-inc.com/cdc14b-antibody-63-773.html PREDICTED MOLECULAR 57 kDa WEIGHT:

Properties

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by PURIFICATION: dialysis

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

OFFICIAL SYMBOL: CDC14B

Dual specificity protein phosphatase CDC14B, CDC14 cell division cycle 14 homolog B, ALTERNATE NAMES: CDC14B

ACCESSION NO.: O60729

GENE ID: 8555

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

CDC14B is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which BACKGROUND: suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

REFERENCES: 1) Bassermann,F., et.al., Cell 134 (2), 256-267 (2008)

2) Rosso,L., et.al., PLoS Biol.(6), E140 (2008)

October 2, 2021 2 https://www.prosci-inc.com/cdc14b-antibody-63-773.html ANTIBODIES FOR RESEARCH USE ONLY.

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