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2017 Festival of Science Program Book

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2017 Festival of Science Program Book The SOM FESTIVAL of SCIENCE WELCOME Dear Colleagues: Welcome to the fifth annual University of Maryland School of MedicineFestival of Science, a day-long celebration of the groundbreaking research being conducted on campus. The theme of this year’s Festival is Mobility and Disability in Aging: Causes, Consequences and Strategies for Restoration. As we have reflected on our extraordinary 210-year history over this last year, and how adeptly the School has evolved to meet the challenges of each passing decade, we also recognize that not everything can move so nimbly with age, including ourselves. However, humans are living longer than ever before due, in large part, to the incredible advances in biomedical research. We are tremendously fortunate to have a dedicated cadre of School of Medicine faculty who have devoted their careers to unraveling the causes and consequences of diseases and conditions often associated with aging, as well as developing innovative approaches to preventing, managing and treating patients. Their groundbreaking work is helping to ensure that our “golden years” can also be our “golden age.” I am pleased that our esteemed Scientific Advisory Council will join us again this year to provide critical advice on our research portfolio. I also wish to extend a warm welcome to our newest Council member, Dr. George Hill, Distinguished Professor Emeritus of Pathology, Microbiology and Immunology at Vanderbilt University. We are deeply honored that Dr. Luigi Ferrucci, Scientific Director of the National Institute on Aging at the National Institutes of Health, will give the keynote address and has graciously agreed to serve as a guest member of our esteemed Scientific Advisory Council. The Festival of Science is a cornerstone of Shared Vision 2020 and the ACCEL-Med (Accelerating Innovation and Discovery in Medicine) Initiative. I extend my deep appreciation to all who helped develop today’s program. I look forward to an engaging and stimulating day of scientific discourse, and appreciate your participation and support of the School of Medicine’s biomedical research enterprise. Sincerely yours, E. Albert Reece, MD, PhD, MBA Executive Vice President for Medical Affairs, University of Maryland John Z. and Akiko K. Bowers Distinguished Professor and Dean, University of Maryland School of Medicine MOBILITY DISABILITY in AGING Causes, Consequences and Strategies for Restoration The SOM FESTIVAL of SCIENCE AGENDA 7:30-7:55am BREAKFAST Coffee, tea and breakfast pastries will be available in the Atrium of Leadership Hall 8:00-8:10am WELCOME E. Albert Reece, MD, PhD, MBA Executive Vice President for Medical Affairs, University of Maryland John Z. and Akiko K. Bowers Distinguished Professor and Dean, University of Maryland School of Medicine 8:15-8:45am KEYNOTE ADDRESS Luigi Ferrucci, MD, PhD Scientific Director, National Institute on Aging National Institutes of Health 8:50-9:05am HISTORY AND PRESENT STATE OF RESEARCH ON AGING IN THE UMSOM AND OVERVIEW OF SESSION ONE Jay Magaziner, PhD, MSHyg Professor and Chair, Department of Epidemiology & Public Health Director, Center for Research on Aging 9:10-11:55am SESSION ONE: Bones, Muscles, Joints, Energetics, and Mobility Moderator: Curt Civin, MD Professor, Department of Pediatrics Director, Center for Stem Cell Biology & Regenerative Medicine Associate Dean for Research 9:10-9:30am Changes in Mobility, Body Composition, and Function After Hip Fracture: Findings From the Baltimore Hip Studies Denise L. Orwig, PhD Associate Professor, Department of Epidemiology & Public Health 9:35-9:55am Bringing Osteoarthritis Into the 21st Century: A Disease of the Whole Joint Marc C. Hochberg, MD, MPH Professor, Department of Medicine Division Head, Rheumatology and Clinical Immunology 10:00-10:20am Moving Muscles in the Context of Aging and Disease Alice S. Ryan, PhD Professor, Department of Medicine 10:25-10:35AM BREAK 10:40-11:20am Microtubule Mechanotransduction in Aging Heart, Skeletal Muscle, and Bone 10:40-10:50am • Heart Muscle W. Jonathan Lederer, MD, PhD Professor, Department of Physiology Director, Center for Biomedical Engineering & Technology 10:50-11:00am • Skeletal Muscle Christopher W. Ward, PhD Associate Professor, Department of Organizational Systems and Adult Health, University of Maryland School of Nursing Associate Professor, Department of Orthopaedics, University of Maryland School of Medicine MOBILITY DISABILITY in AGING The SOM FESTIVAL of SCIENCE 11:00-11:10am • Bone Joseph P. Stains, PhD Associate Professor, Department of Orthopaedics Interim Director of Musculoskeletal Research 11:25-11:55am SESSION ONE Q&A NOON-12:55pm LUNCH Provided in the Atrium of Leadership Hall 1:00-3:30pm SESSION TWO: Brain, Balance, Disease and Mobility Moderator: James B. Kaper, PhD Senior Associate Dean for Academic Affairs Professor and Chair, Department of Microbiology & Immunology 1:00-1:15pm OVERVIEW OF SESSION TWO Mark Rogers, PT, PhD Professor and Chair, Department Physical Therapy & Rehabilitation Science 1:20-1:40pm Mobility & Disability in Parkinson Disease: Decoding Patterns in Multidimensional Data Lisa M. Shulman, MD Eugenia Brin Professorship in Parkinson’s Disease and Movement Disorders The Rosalyn Newman Distinguished Scholar in Parkinson’s Disease Professor, Department of Neurology and Director of the Division of Movement Disorders Director, University of Maryland Parkinson’s Disease and Movement Disorders Center 1:45-2:05pm Robot-Aided Musculoskeletal Rehabilitation Li-Qun Zhang, PhD Professor, Department of Physical Therapy & Rehabilitation Science 2:10-2:30pm Protective Arm Movements for Fall Prevention in the Elderly Kelly P. Westlake, PhD, MSc, PT Assistant Professor, Department of Physical Therapy & Rehabilitation Science 2:35-2:55pm Vascular Disease, Mobility and Cognition Brajesh K. Lal, MBBS Professor, Department of Surgery 3:00-3:30pm SESSION TWO Q&A 3:35pm CLOSING REMARKS E. Albert Reece, MD, PhD, MBA RECEPTION Dessert and coffee reception will be held in the Atrium of Leadership Hall immediately following the Festival Accreditation Statement The UMSOM is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Credit Designation Statement The UMSOM designates this Live Activity for a maximum of 6.50 AMA PRA Category 1 Credits.™ Physicians should claim only the credit commensurate with the extent of their participation in the activity. MOBILITY DISABILITY in AGING Causes, Consequences and Strategies for Restoration The SOM FESTIVAL of SCIENCE CME INFORMATION CME SPONSORSHIP This educational activity is sponsored by the University of Maryland School of Medicine. ACTIVITY DIRECTOR E. Albert Reece, MD, PhD, MBA Executive Vice President for Medical Affairs, University of Maryland John Z. and Akiko K. Bowers Distinguished Professor and Dean University of Maryland School of Medicine TARGET AUDIENCE The target audience for this educational activity includes physicians, clinicians, researchers and other healthcare professionals with an interest in mobility and disability in the aging, LEARNING OBJECTIVES At the conclusion of this activity, participants should be able to: • Describe the features of bone, muscle and joint function in normal aging and after hip fracture. • Describe age-dependent alterations in cellular function in heart, skeletal muscle and bone, and the role of exercise and nutrition in muscle recovery. • Identify the roles of vascular and neurologic diseases and their impact on balance, mobility and cognition. ACCREDITATION AND CREDIT DESIGNATION The University of Maryland School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The University of Maryland School of Medicine designates this Live activity for a maximum of 6.50 AMA PRA Category 1 Credits.™ Physicians should claim only the credit commensu- rate with the extent of their participation in the activity. DISCLOSURE It is the policy of the University of Maryland School of Medicine to ensure balance, inde- pendence, objectivity, and scientific rigor in all of its educational activities. In accordance with this policy, all persons in a position to control the educational content of this activity must disclose any relevant financial relationships they have with commercial interests. Any identified conflicts of interest must be resolved prior to the speaker’s presentation. The following individuals have disclosed no relevant financial relationships with commercial interests: E. Albert Reece, MD, PhD, MBA; Curt Civin, MD; Kevin Enright; Luigi Ferrucci, MD, PhD; Marc Hochberg, MD, MPH; James Kaper, PhD; Brajesh Lal, MBBS; W. Jonathan Lederer, MD, PhD; Jay Magaziner, PhD, MSHyg; Denise Orwig, PhD; Mark Rogers, PT, PhD; Julie Rosen, PhD; Alice Ryan, PhD; Lisa Shulman, MD; Joseph Stains, PhD, Christopher Ward, PhD; and Kelly Westlake, PhD, MSc, PT. MOBILITY DISABILITY in AGING The SOM FESTIVAL of SCIENCE The following individuals have disclosed relevant financial relationships with commercial interests: Li-Qun Zhang, PhD Rehabtek LLC – Rehabtek received federal SBIR phase I and II grants in developing the rehabilitation robot and provided it to our relevant research/clinical studies free of charge. I and spouse hold equity position in Rehabtek. I also received relevant research grants. University of Maryland School of Medicine Office of CME staff members have disclosed no relevant financial relationships. DISCUSSION OF OFF-LABEL OR INVESTIGATIONAL
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