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Annual Report 2019 ANNUAL REPORT dkms.de COVER IMAGE: Staff at the DKMS Life Science Lab use an automated system to ascertain the CMV status of donor samples. For more about the work of the lab, turn to page 22. PUBLICATION DETAILS Title: DKMS Annual Report 2019 Published by: DKMS gemeinnützige GmbH Kressbach 1, 72072 Tübingen T 07071 943-0 F 07071 943-1499 [email protected] dkms.de Board of Directors: Dr. Elke Neujahr (Chair), Dr. Dr. Alexander Schmidt, Sirko Geist Editorial Office: DKMS gGmbH, Corporate Communications Design and layout: MALZKORN Kommunikation & Gestaltung GmbH Consultancy, copy-editing, proof-reading: Goerke Public Relations GmbH Photo credits: Peter Godry (P. 4), Florian Büh (P. 6, 8, 12, 14), SV Bentheim (P. 7), Daniela Decker (P. 7), DKMS (P. 7, 8, 9, 10, 11, 20, 28, 29, 33, 41, 42, 51), Eden Books (P. 7), Privat (P. 7, 11, 14, 51, 54), Thomas Faehnrich Fotografie (P. 8), DFV (P. 8), Nina Stiller (P. 9), Michèl Passin (P. 9), Maximilian Möller (P. 9), Markus Nass/BrauerPhotos für DKMS LIFE (P. 10), Daniel Hinz für DKMS LIFE (P. 10), R.SH (P. 11), Patric Fouad (P. 16), DKMS LSL (P. 22, 23), Shutterstock (P. 26), Bert Spangemacher (P. 27, 30, 54), Stephan Schütze für B2Run (P. 31), DKMS-BMST (P. 39), Uniklinikum Frankfurt (P. 51) Printed by: DFS Druck Brecher GmbH, Köln DFS Druck Brecher GmbH, Köln * All figures as of 31.12.2019 CONTENTS EDITORIAL 4 2019 ANNUAL REVIEW 6 NEW REGISTRATIONS 12 DONOR STATISTIC 15 SPOTLIGHT ON YOUNG PEOPLE 16 THE CHALLENGES 19 INTERVIEW WITH DR. ALEXANDER SCHMIDT 20 DKMS LIFE SCIENCE LAB 22 IMPROVING THE CHANCES OF SURVIVAL 26 WORKING FOR DKMS 30 SOCIAL MEDIA 33 QUALITY PROJECTS 34 OVERALL DONOR NUMBERS 37 INTERNATIONAL MILESTONES 38 MONEY DONATIONS SAVE LIVES 42 OUR MISSION 44 FACTS & FIGURES 45 RISK MANAGEMENT 52 STRUCTURE OF DKMS 53 OUR EDITORIAL TEAM 54 STEM CELL DONATIONS MADE BY DKMS DONORS BASED IN GERMANY (1991–2019) Russia 908 Russia Canada 908 1,845 Canada 1,845 USA Japan 17,093 in Europe: 2 USA Japan 17,093 in18,661 Europe:Germany Iran 2 111 18,661 Germany5,059 France Iran South Korea | 29 Cuba 3,438 Italy 111 5,059 France3,396 United Kingdom India South Korea | 29 THE 1 3,438 Italy Cuba 2,176 Netherlands 215 Hong Kong | 10 Mexico 3,396 United Kingdom India 1 1,711 Spain Mexico11 2,176 Netherlands 215 Hong Kong | 10 1,555 Belgium 11 1,711 Spain JOURNEY TO 1,555 Belgium1,410 Poland 1,410 Poland1,191 Sweden Turkey | 1,332 Colombia 1,191 Sweden1,118 Czech Republic Turkey | 1,332 Saudi Arabia | 21 1,118 Czech Republic Sri Lanka | 1 A STEM CELL Colombia5 Saudi Arabia | 21 879 Austria JordanSri Lanka| 1 | 1 5 879 Austria760 Denmark Jordan | 1 Thailand | 1 LebanonThailand | 2 | 1 760 Denmark694 Switzerland Malaysia | 2 INSERT IN THE MIDDLE OF THE BOOK Lebanon | 2 Brazil 694 Switzerland573 Finland IsraelM a| l395aysia | 2 TRANSPLANT 573 Finland Israel | 395 Singapore | 24 Brazil289 505 Greece Singapore | 24 289 505 Greece Anzahl der 426 Hungary426 Hungary Stammzellspenden 356 Norway356 Norway von DKMS-Spendern 333 Portugal333 Portugal ChiClehile aus Deutschland 306 Lithuania306 Lithuania Australia Australia 29 29 277 Slovakia277 Slovakia 879 879 Anzahl70,072 der in die Welt hinaus 264 Ireland264 Ireland Stammzellspenden von 1991 bis 2017 UrugUuaruyguay 226 Belarus226 Belarus stemstem cell donations South AfricaSouth Africa 16 16 von DKMS-Spendernbyby DKMSDKMS Germany 188 Croatia188 Croatia 177 177 DONATIONS mehr als 10.001 aus Deutschland 156 Slovenia156 Slovenia 1.001–10.000 122 Romania in die Welt hinaus ArgeAnrtgineantina 122 Romania 501–1.000 357 90 Serbia von 1991 bis 2017 357 90 Serbia PROCURED 201–500 82 Estonia New Zealand 77 Bulgaria82 Estonia 174 New Zealand More than 10,001 101–200 77 Bulgaria 174 The journey to a stem cell transplant 1,001 - 10,000 51–100 4 Macedonia WORLDWIDE 4 Macedonia 501–1,000 11–50 201–500 1–10 101–200 51–100 11–50 1–10 Donations procured worldwide dkms.de EDITORIAL 4 I ANNUAL REPORT 2019 EDITORIAL Dear Reader, Nearly 30 years ago, Peter Harf, founder of DKMS, to obtaining stem cells for a patient in need, speed, made a promise to his wife, who was suff ering from availability, and quality are critical. leukemia. Now, more than ever, his promise is our moti- There are numerous dimensions to our missi- vation: to do whatever we can to give every blood can- on. Wherever we feel our expertise can improve the cer patient a second chance at life – across borders chances of cure and survival, we are quick to get in- and around the world. Every life saved is another suc- volved. This is why we are constantly developing our cess of immeasurable value. global operations, and now have offi ces not only in The coronavirus pandemic has presented us Germany, but also in the US, the UK, Poland, Chile, all with an unprecedented challenge. At DKMS, we and India (see page 38 onwards). Furthermore, I am were quick to respond to the new situation, intensi- pleased to report that in 2019 we were able to en- fying our partnerships around the world and forging ter into a forward-looking partnership with the Sun- new pathways to ensure we continue to fulfi l our fl ower Fund in South Africa. Our global activities are mission without fail. helping to give people everywhere a second chan- Blood cancer cannot be quarantined and ce at life. To support our eff orts, we are increasing- knows no risk areas. Above all, it leaves little time ly investing in providing access to transplantation to react. Every 35 seconds someone, somewhere in and working closely with our medical specialists and the world is diagnosed with this deadly disease. For scientists to develop life-saving therapies (see page many, the only chance of survival is a stem cell trans- 26 onwards). plantation with healthy cells from a matching donor. Until we have delivered on the promise our This is what drives our entire team worldwide. founder made almost 30 years ago, we will not give Together, we ensure that the complete chain up. Every individual should have a second chance at of activities preceding a stem cell transplant runs life in their fi ght against blood cancer. Our greatest smoothly – across national borders and despite the wish is to beat this disease – and you can help us: special circumstances we fi nd ourselves in due to simply register with DKMS, make a fi nancial donati- the coronavirus pandemic. To make that happen, our on, or spread our message so even more people sign 900-plus employees in seven DKMS locations world- up as potential stem cell donors. wide achieve the incredible, which fi lls me with grati- Together, we have already achieved so much. tude and pride. DKMS donors have already given over 83,000 people The main enablers in all of this, however, around the world a second chance at life. are our donors. I would like to take this opportuni- ty to thank over 10 million people around the world for their willingness to help and for signing up with Best regards DKMS so they can donate stem cells if the need ari- ses. Every one of them is giving the gift of hope and courage to countless patients. This annual report off ers an overview of our work in 2019, before the Covid crisis hit. It was a year in which we once again celebrated some major suc- Dr. Elke Neujahr cesses in our mission. Most importantly though, it Chair of the Board of Directors, was a year in which we were able to lay key founda- Global CEO DKMS Group tions for the future, including the current challenges presented by the coronavirus pandemic. Our mind- set is fundamentally future-focused, centering on the development of new ideas and consistent pro- cess improvement to benefi t every patient whose life depends on our work – because when it comes ANNUAL REPORT 2019 I 5 HIGHLIGHTS ROLE MODELS AND INSPIRATIONS: 2019 AT DKMS Impressive numbers, fascinating stories, amazing commitment: 2019 was another moving year for DKMS, packed with heroic donors, emotional patient stories, new records set, and plenty of new ideas in the fight against blood cancer. We look back at the year that was… On WBCD in May 2019, the Integrated Comprehensive School in Erfurt was presented with an award for its fantastic commitment. 6 I ANNUAL REPORT 2019 HIGHLIGHTS January The life-saving team When it comes to doing good, the footballers of SV Bentheim are in a league of their own. Five of them have already donated stem cells to give patients a second chance at life. Jackpot! From left to right: Oliver Belt, Hendrik Buttler, Lars Somberg, Patrick Neise. Federal Cross of Merit for DKMS supporters Absent: Ole Somberg Henning Krautmacher, frontman with the German band Höhner, has been awarded the Federal Merit Cross on Ribbon for his passionate social commitment. The 63-year-old was presented with the accolade at the State Chancellery in Düsseldorf by Armin Laschet, Minister President of North Rhine-Westphalia. Henning has been a dedicated supporter of DKMS for 21 years. “This Cross inspires me to carry on doing even more,” said the delighted singer. Armin Laschet (left) and singer Henning Krautmacher February A moving reading on World Cancer Day On World Cancer Day, the author and blogger Ines Gillmeister presented the Bestseller (1) touching story of her husband, Simon, who Simon and Ines (2) died of a malignant tumor in 2018.
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