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Kanker Begrijpen De Wijsheid Van Het Lichaam TherapieWijzer Kanker begrijpen De wijsheid van het lichaam voeding beweging leefstijl bioactieve stoffen supplementen niet-toxische therapieën chemo & straling ondersteunen bijwerkingen beperken Hilde Maris Referenties 1. Hoe ontstaat kanker? Alzoubi K, Khabour O, Hussain N, et al. Evaluation of vita- cine. 6th edition. Hamilton (ON): BC Decker; 2003. min B12 effects on DNA damage induced by pioglitazone. Liu HK, Wang Q, Li Y, et al. Inhibitory effects of gamma- Mutat Res. 2012 Oct 9;748(1-2):48-51. tocotrienol on invasion and metastasis of human gastric Azqueta A, Collins AR. Carotenoids and DNA damage. adenocarcinoma SGC-7901 cells. J Nutr Biochem. 2010 Mutat Res. 2012 May 1;733(1-2):4-13. Mar;21(3):206-13. Barrett JC. Mechanisms of multistep carcinogenesis and Liu R, Fu A, Hoffman AE, et al. Melatonin enhances DNA carcinogen risk assessment. Environ Health Perspect. repair capacity possibly by affecting genes involved in 1993 Apr;100:9-20. DNA damage responsive pathways. BMC Cell Biol. 2013 Bhat FA, Sharmila G, Balakrishnan S, et al. Querce- Jan 7;14:1. tin reverses EGF-induced epithelial to mesenchymal Lotan R1. Retinoids as modulators of tumor cells invasion transition and invasiveness in prostate cancer (PC-3) cell and metastasis. Semin Cancer Biol. 1991 Jun;2(3):197- line via EGFR/PI3K/Akt pathway. J Nutr Biochem. 2014 208. Nov;25(11):1132-9. Lyons NM, O’Brien NM. Modulatory effects of an algal Cash SW, Beresford SA, Vaughan TL, et al. Recent physi- extract containing astaxanthin on UVA-irradiated cells in cal activity in relation to DNA damage and repair using the culture. J Dermatol Sci. Oct 2002;30(1):73-84. comet assay. J Phys Act Health. 2014 May;11(4):770-6. Mali AV, Wagh UV, Hegde MV, et al. In vitro anti-metasta- Chamberland JP, Moon HS. Down-regulation of malignant tic activity of enterolactone, a mammalian lignan derived potential by alpha linolenic acid in human and mouse from flax lignan, and down-regulation of matrix metal- colon cancer cells. Fam Cancer. 2015 Mar;14(1):25-30. loproteinases in MCF-7 and MDA MB 231 cell lines. Indian Cooper GM.The Cell: A Molecular Approach. 2nd edition. J Cancer. 2012 Jan-Mar;49(1):181-7. Sunderland (MA): Sinauer Associates; 2000. Mathers JC, Coxhead JM, Tyson J. Nutrition and DNA Coppola Domenico. Mechanisms of Oncogenesis. An repair--potential molecular mechanisms of action. Curr update on Tumorigenesis. Springer Science & Business Cancer Drug Targets. Aug 2007;7(5):425-31. Media, 2010. ISBN 978-9048137244. Mathers JC. The biological revolution – towards a mecha- Diamond L, O’Brien TG, Baird WM. Tumor promoters and nistic understanding of the impact of diet on cancer risk. the mechanism of tumor promotion. Adv Cancer Res. Mutat Res. Jul 13 2004;551(1-2):43-49. 1980;32:1-74. Nangia-Makker P, Hogan V, Honjo Y, et al. Inhibition of Enquist IB, Good Z, Jubb AM, et al. Lymph node-indepen- human cancer cell growth and metastasis in nude mice by dent liver metastasis in a model of metastatic colorectal oral intake of modified citrus pectin. J Natl Cancer Inst. cancer. Nat Commun. 2014 Mar 26;5:3530. 2002 Dec 18;94(24):1854-62. Fenech M, Aitken C, Rinaldi J. Folate, vitamin B12, ho- Palange AL, Di Mascolo D, Singh J, et al. Modulating the mocysteine status and DNA damage in young Australian vascular behavior of metastatic breast cancer cells by adults. Carcinogenesis. 1998 Jul;19(7):1163-71. curcumin treatment. Front Oncol. 2012 Nov 15;2:161. Gerhauser C1. Cancer chemoprevention and nutriepige- Park JS, Kim KM, Kim MH, et al. Resveratrol inhibits tu- netics: state of the art and future challenges. Top Curr mor cell adhesion to endothelial cells by blocking ICAM-1 Chem. 2013;329:73-132. expression. Anticancer Res. 2009 Jan;29(1):355-62. Hanahan D, Weinberg RA. Hallmarks of cancer: the next Raffoul JJ, Heydari AR, Hillman GG. DNA Repair and Can- generation. Cell. 2011 Mar 4;144(5):646-74. cer Therapy: Targeting APE1/Ref-1 Using Dietary Agents. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. J Oncol. 2012;2012:370481. 2000 Jan 7;100(1):57-70. Ramachandran L, Nair CK. Protection against genotoxic Hattis D, Chu M, Rahmioglu N, et al. A preliminary damages following whole body gamma radiation exposure operational classification system for nonmutagenic in mice by lipoic acid. Mutat Res. 2011 Sep 18;724(1- modes of action for carcinogenesis. Crit Rev Toxicol. 2):52-8. 2009;39(2):97-138. Raz A, Lotan R. Endogenous galactoside-binding lectins: Ho CK, Choi SW, Siu PM, et al. Effects of single dose and a new class of functional tumor cell surface mole- regular intake of green tea (Camellia sinensis) on DNA cules related to metastasis. Cancer Metastasis Rev. damage, DNA repair, and heme oxygenase-1 expression 1987;6(3):433-52. in a randomized controlled human supplementation study. Robertson KD, Jones PA. DNA methylation: past, Mol Nutr Food Res. 2014 Jun;58(6):1379-83. present and future directions. Carcinogenesis. 2000 Hori A, Kasai H, Kawai K, et al. Coffee intake is associated Mar;21(3):461-7. with lower levels of oxidative DNA damage and decreasing Ronen A, Glickman BW. Human DNA repair genes. Envi- body iron storage in healthy women. Nutr Cancer. ron Mol Mutagen. 2001;37(3):241-83. 2014;66(6):964-9. Slyskova J, Lorenzo Y, Karlsen A, et al. Both genetic and Hwang ES, Lee HJ. Inhibitory effects of lycopene on dietary factors underlie individual differences in DNA da- the adhesion, invasion, and migration of SK-Hep1 mage levels and DNA repair capacity. DNA Repair (Amst). human hepatoma cells. Exp Biol Med (Maywood). 2006 2014 Apr;16:66-73. Mar;231(3):322-7. Stamenkovic I. Matrix metalloproteinases in tumor Jiang J, Sliva D. Novel medicinal mushroom blend sup- invasion and metastasis. Semin Cancer Biol. 2000 presses growth and invasiveness of human breast cancer Dec;10(6):415-33. cells. Int J Oncol. 2010 Dec;37(6):1529-36. Strzelczyk JK, Wiczkowski A. Oxidative damage and carci- Jin H, Lee WS, Yun JW, et al. Flavonoids from Citrus nogenesis. Contemp Oncol (Pozn). 2012;16(3):230-3. unshiu Marc. inhibit cancer cell adhesion to endothelial Sung V, Feldman D. 1,25-Dihydroxyvitamin D3 decreases cells by selective inhibition of VCAM-1. Oncol Rep. 2013 human prostate cancer cell adhesion and migration. Mol Nov;30(5):2336-42. Cell Endocrinol. 2000 Jun;164(1-2):133-43. Kufe DW, Pollock RE, Weichselbaum RR, et al., editors. Supabphol A, Muangman V, Chavasiri W, et al. N- Multistage Carcinogenesis. Holland-Frei Cancer Medi- acetylcysteine inhibits proliferation, adhesion, migration 2 Referenties ................................................................................................................................................................... TherapieWijzer and invasion of human bladder cancer cells. J Med Assoc oncogenesis. Cell. 1991 Jun 28;65(7):1097-8. Thai. 2009 Sep;92(9):1171-7. Xia SH, Wang J, Kang JX. Decreased n-6/n-3 fatty acid Tantivejkul K, Vucenik I, Shamsuddin AM. Inositol hexap- ratio reduces the invasive potential of human lung cancer hosphate (IP6) inhibits key events of cancer metastasis: cells by downregulation of cell adhesion/invasion-related I. In vitro studies of adhesion, migration and invasion of genes. Carcinogenesis. 2005 Apr;26(4):779-84. MDA-MB 231 human breast cancer cells. Anticancer Res. Yamasaki M, Iwase M, Kawano K, et al. α-Lipoic acid sup- 2003 Sep-Oct;23(5A):3671-9. presses migration and invasion via downregulation of cell Tantivejkul K, Vucenik I, Shamsuddin AM. Inositol hexap- surface β1-integrin expression in bladder cancer cells. J hosphate (IP6) inhibits key events of cancer metastasis: II. Clin Biochem Nutr. 2014 Jan;54(1):18-25. Effects on integrins and focal adhesions. Anticancer Res. Yousef JM, Mohamed AM1. Prophylactic role of B vitamins 2003 Sep-Oct;23(5A):3681-9. against bulk and zinc oxide nano-particles toxicity induced Tyson J, Mathers JC. Dietary and genetic modulation of oxidative DNA damage and apoptosis in rat livers. Pak J DNA repair in healthy human adults. Proc Nutr Soc. Feb Pharm Sci. 2015 Jan;28(1):175-84. 2007; 66(1):42-51. Yu LG, Andrews N, Zhao Q, et al. Galectin-3 interaction Vanamala J. Food Systems Approach to Cancer Preven- with Thomsen-Friedenreich disaccharide on cancer-as- tion. Crit Rev Food Sci Nutr. 2015 Jul 20:0. sociated MUC1 causes increased cancer cell endothelial Wang L, Gao S, Jiang W, et al. Antioxidative dietary adhesion. J Biol Chem. 2007 Jan 5;282(1):773-81. compounds modulate gene expression associated with Zeisel SH. Dietary choline deficiency causes DNA strand apoptosis, DNA repair, inhibition of cell proliferation and breaks and alters epigenetic marks on DNA and histones. migration. Int J Mol Sci. 2014 Sep 15;15(9):16226-45. Mutat Res. 2012 May 1;733(1-2):34-8. Weng CJ, Yen GC. Flavonoids, a ubiquitous dietary phen- Zhang Y, Han G, Fan B, et al. Green tea (-)-epigalloca- olic subclass, exert extensive in vitro anti-invasive and techin-3-gallate down-regulates VASP expression and in vivo anti-metastatic activities. Cancer Metastasis Rev. inhibits breast cancer cell migration and invasion by 2012 Jun;31(1-2):323-51. attenuating Rac1 activity. Eur J Pharmacol. 2009 Mar Williams GT. Programmed cell death: apoptosis and 15;606(1-3):172-9. 2. Waarom ontstaat kanker? 2.1. Voedingspatroon intake of multiple relevant carcinogens found in meat and charcuterie products. Sci Total Environ. 2015 May Abdulla M, Gruber P. Role of diet modification in cancer 1;514:33-41. prevention. Biofactors. 2000;12(1-4):45-51. Jin L, Lim M, Zhao S, et al.
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