Anti-RFC3 (internal region) polyclonal antibody (DPABH-26536) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proliferating cell nuclear antigen (PCNA) and activator 1.

Immunogen Synthetic peptide derived from an internal sequence of Human RFC3.

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Immunogen affinity purified

Conjugate Unconjugated

Applications WB, IHC-P

Format Liquid

Size 100 μg

Buffer pH: 7.40; Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride. Note: PBS is without Mg2+ and Ca2+

Preservative 0.02% Sodium Azide

Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

GENE INFORMATION

Gene Name RFC3 (activator 1) 3, 38kDa [ Homo sapiens ]

Official Symbol RFC3

Synonyms RFC3; replication factor C (activator 1) 3, 38kDa; replication factor C (activator 1) 3 (38kD); replication factor C subunit 3; A1 38 kDa subunit; MGC5276; RFC; 38 kD subunit; RFC38; RFC, 38 kD subunit; RF-C 38 kDa subunit; activator 1 subunit 3; activator 1 38 kDa subunit; replication factor C 38 kDa subunit;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Gene ID 5983

Protein Refseq NP_002906

UniProt ID A0A024RDQ8

Chromosome Location 13q13.2

Pathway Activation of ATR in response to replication stress; BRCA1-associated genome surveillance complex (BASC); Cell Cycle; Cell Cycle Checkpoints; Cell Cycle, Mitotic; Maintenance; DNA Repair

Function ATP binding; contributes_to ATPase activity; contributes_to DNA binding; DNA clamp loader activity; nucleotide binding; binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved