Anti-RFC3 (internal region) polyclonal antibody (DPABH-26536) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. Immunogen Synthetic peptide derived from an internal sequence of Human RFC3. Isotype IgG Source/Host Rabbit Species Reactivity Human Purification Immunogen affinity purified Conjugate Unconjugated Applications WB, IHC-P Format Liquid Size 100 μg Buffer pH: 7.40; Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride. Note: PBS is without Mg2+ and Ca2+ Preservative 0.02% Sodium Azide Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. GENE INFORMATION Gene Name RFC3 replication factor C (activator 1) 3, 38kDa [ Homo sapiens ] Official Symbol RFC3 Synonyms RFC3; replication factor C (activator 1) 3, 38kDa; replication factor C (activator 1) 3 (38kD); replication factor C subunit 3; A1 38 kDa subunit; MGC5276; RFC; 38 kD subunit; RFC38; RFC, 38 kD subunit; RF-C 38 kDa subunit; activator 1 subunit 3; activator 1 38 kDa subunit; replication factor C 38 kDa subunit; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Entrez Gene ID 5983 Protein Refseq NP_002906 UniProt ID A0A024RDQ8 Chromosome Location 13q13.2 Pathway Activation of ATR in response to replication stress; BRCA1-associated genome surveillance complex (BASC); Cell Cycle; Cell Cycle Checkpoints; Cell Cycle, Mitotic; Chromosome Maintenance; DNA Repair Function ATP binding; contributes_to ATPase activity; contributes_to DNA binding; DNA clamp loader activity; nucleotide binding; protein binding; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.