Consortia

The UK10K Project Consortium

(Participants are arranged by project role, and then alphabetically, excluding the Writing group which is ordered based on contribution).

Corresponding Authors

Nicole Soranzo 1, Richard Durbin 1

Writing group

Klaudia Walter* 1, Josine Min* 2, Jie Huang* 1, Lucy Crooks* 1, 3, Yasin Memari 1, Shane McCarthy 1, John R.B. Perry 4,5, ChangJiang Xu 6,7, Marta Futema 8, Daniel Lawson 2, Valentina Iotchkova 1,9, Stephan Schiffels 1, Audrey Hendricks 1,10, Petr Danecek 1, Rui Li 6,11, James Floyd 1,12, Inês Barroso 1, 13, Steve E. Humphries 8, Matthew E. Hurles 1, Eleftheria Zeggini 1, Jeffrey C. Barrett 1, Vincent Plagnol 14, Brent Richards 4,6,7,11, Celia Greenwood 6,7,11,15, Nicholas Timpson 2, Richard Durbin 1, Nicole Soranzo 1

* Joint contribution

Production group

Senduran Balasubramaniam 1, Peter Clapham 1, Guy Coates 1, Tony Cox 1, Allan Daly 1, Petr Danecek 1, Yuanping Du 16, Richard Durbin 1, Sarah Edkins 1, Peter Ellis 1, Paul Flicek 1,9, Xiaosen Guo 16,17, Xueqin Guo 16, Liren Huang 16, David K. Jackson 1, Chris Joyce 1, Thomas Keane 1, Anja Kolb-Kokocinski 1, Cordelia Langford 1, Yingrui Li 16, Jieqin Liang 16, Hong Lin 16, Ryan Liu 18, John Maslen 1, Shane McCarthy (co-chair) 1, Dawn Muddyman 1, Michael A. Quail 1, Jim Stalker (co-chair) 1, Jianping Sun 6, 7, Jing Tian 16, Guangbiao Wang 16, Jun Wang 16,17,19,20,21, Yu Wang 16, Kim Wong 1, Pingbo Zhang 16

Cohorts group

Inês Barroso 1,13, 9, Chris Boustred 2, Marie-Jo Brion 2, Lu Chen 1,22, Gail Clement 4, Petr Danecek 1, George Davey Smith 2, Ian N. M. Day 2, Aaron Day- Williams 1,23, Thomas Down 1,24, Ian Dunham 9, Richard Durbin 1, David Evans 2,25, Ghazaleh Fatemifar 2, Tom Gaunt 2, Matthias Geihs 1, Celia Greenwood 6,7,11,15, Deborah Hart 4, Audrey Hendricks 1,10, Bryan Howie 26, Jie Huang 1, Tim Hubbard 24,1, Pirro Hysi 4, Valentina Iotchkova 1,9, Yalda Jamshidi 27, John Kemp 2,25, Genevieve Lachance 4, Daniel Lawson 2, Monkol Lek 28, Margarida Lopes 1,29, Daniel G. MacArthur 1,28,30, Jonathan Marchini 31, Mangino Massimo 4, Iain Mathieson 32, Shane McCarthy 1, Yasin Memari 1, Sarah Metrustry 4, Josine Min 2, Alireza Moayyeri 4,33, Dawn Muddyman 1, Kate Northstone 2, Kalliope Panoutsopoulou 1, Lavinia Paternoster 2, John R.B. Perry 4,5, Lydia Quaye 4, Brent Richards (co-chair) 4,6,7,11, Susan Ring 2,34, Graham R.S. Ritchie 1,9, Stephan Schiffels 1, Hashem Shihab 2, So-Youn Shin 1,2, Kerrin Small 4, Maria Soler Artigas 35, Nicole Soranzo (co-chair) 1, Lorraine Southam 1,29, Tim Spector 4, Beate St Pourcain 2,36,37, Gabriela Surdulescu 4, Ioanna Tachmazidou 1, Nicholas Timpson (co-chair) 2, Martin D. Tobin 35,38, Ana Valdes 4, Peter M. Visscher 39,25, Louise V. Wain 35, Klaudia Walter 1, Kirsten Ward 4, Scott G. Wilson 4,40,41, Kim Wong 1, Jian Yang 39,25, Eleftheria Zeggini 1, Feng Zhang 4,83, Hou-Feng Zheng 6,11

Neuro group

Richard Anney 42, Muhammad Ayub 43, Jeffrey C. Barrett 1, Douglas Blackwood 44, Patrick Bolton 45, Gerome Breen 45, 46, David Collier 47,48, Nick Craddock 49, Lucy Crooks 1,3, Sarah Curran 45,50,51, David Curtis 52, Richard Durbin 1, Louise Gallagher 42, Daniel Geschwind 53, Hugh Gurling 52, Peter Holmans 49, Irene Lee 54, Jouko Lönnqvist 55, Shane McCarthy 1, Peter McGuffin 45, Andrew McIntosh 44, Andrew G. McKechanie 56,44, Andrew McQuillin 52, James Morris 1, Dawn Muddyman 1, Michael C. O'Donovan 49, Michael J. Owen (co-chair) 49, Aarno Palotie (co-chair) 1,57,58, Jeremy R. Parr 59, Tiina Paunio 55,60, Olli Pietilainen 1,55,57, Karola Rehnström 1, Sally I. Sharp 52, David Skuse 54, David St Clair 61, Jaana Suvisaari 55, James T.R. Walters 49, Hywel Williams 49

Obesity group

Inês Barroso (co-chair) 1,13, Elena Bochukova 13, Rebecca Bounds 13, Richard Durbin 1, Sadaf Farooqi (co-chair) 13, Audrey Hendricks 1,10, Julia Keogh 13, Gaëlle Marenne 1, Shane McCarthy 1, Dawn Muddyman 1, Stephen O'Rahilly 13, Ioanna Tachmazidou 1, Eleanor Wheeler 1, Eleftheria Zeggini 1

Rare group

Saeed Al Turki 1,62, Carl Anderson 1, Dinu Antony 63, Inês Barroso 1,13, Phil Beales 63, Jamie Bentham 64, Shoumo Bhattacharya 64, Mattia Calissano 65, Keren Carss 1, Krishna Chatterjee 13, Sebhattin Cirak 65,66, Catherine Cosgrove 64, Richard Durbin 1, David R. Fitzpatrick (co-chair) 67, James Floyd 1,12, A. Reghan Foley 65, Christopher S. Franklin 1, Marta Futema 8, Detelina Grozeva 68, Steve E. Humphries 8, Matthew E. Hurles (co-chair) 1, Shane McCarthy 1, Hannah M. Mitchison 63, Dawn Muddyman 1, Francesco Muntoni 65, Stephen O'Rahilly 13, Alexandros Onoufriadis 24, Victoria Parker 13, Felicity Payne 1, Vincent Plagnol 14, Lucy Raymond 68, Nicola Roberts 68, David B. Savage 13, Peter Scambler 63, Miriam Schmidts 63, Nadia Schoenmakers 13, Robert K. Semple 13, Eva Serra 1, Olivera Spasic-Boskovic 68, Elizabeth Stevens 65, Margriet van Kogelenberg 1, Parthiban Vijayarangakannan 1, Klaudia Walter 1, Kathleen A. Williamson 67, Crispian Wilson 68, Tamieka Whyte 65

Statistics group

Ciampi, Antonio 7, Celia Greenwood (co-chair) 6,7,11,15, Audrey Hendricks 1,10, Rui Li 6,11, Sarah Metrustry 4, Karim Oualkacha 69, Ioanna Tachmazidou 1, ChangJiang Xu 6,7, Eleftheria Zeggini (co-chair) 1 Ethics group

Martin Bobrow 68, Patrick Bolton 45, Richard Durbin 1, David R. Fitzpatrick 67, Heather Griffin 70, Matthew E. Hurles (co-chair) 1, Jane Kaye (co-chair) 70, Karen Kennedy 1, Alastair Kent 71, Dawn Muddyman 1, Francesco Muntoni 65, Lucy Raymond 68, Robert K. Semple 13, Carol Smee 1, Tim Spector 4, Nicholas Timpson 2

Incidental findings group

Ruth Charlton 72, Rosemary Ekong 73, Marta Futema 8, Steve E. Humphries 8, Farrah Khawaja 74, Luis R. Lopes 75, Nicola Migone 76, Stewart J. Payne 77, Vincent Plagnol (chair) 14, Rebecca C. Pollitt 78, Sue Povey 73, Cheryl K. Ridout 79, Rachel L. Robinson 72, Richard Scott 80, Adam Shaw 81, Petros Syrris 75, Rohan Taylor 74, Anthony M. Vandersteen 82

Management committee

Jeffrey C. Barrett 1, Inês Barroso 1,13, George Davey Smith 2, Richard Durbin (chair) 1, Sadaf Farooqi 13, David R. Fitzpatrick 67, Matthew E. Hurles 1, Jane Kaye 70, Karen Kennedy 1, Cordelia Langford 1, Shane McCarthy 1, Dawn Muddyman 1, Michael J. Owen 49, Aarno Palotie 1,57,58, Brent Richards 4,6,7,11, Nicole Soranzo 1, Tim Spector 4, Jim Stalker 1, Nicholas Timpson 2, Eleftheria Zeggini 1

Affiliations

1. The Wellcome Trust Sanger Institute, Wellcome Trust Campus, Hinxton CB10 1HH, Cambridge, UK. 2. MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Clifton, Bristol, BS8 2BN, UK. 3. Sheffield Diagnostic Genetics Service, Sheffield Childrens' NHS Foundation Trust, Western Bank, Sheffield S10 2TH, UK. 4. The Department of Twin Research & Genetic Epidemiology, King’s College London, St Thomas’ Campus, Lambeth Palace Road, London, SE1 7EH, UK. 5. MRC Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, UK 6. Lady Davis Institute, Jewish General Hospital, Montreal, Quebec, Canada. 7. Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada 8. Cardiovascular Genetics, BHF Laboratories, Rayne Building, Institute Cardiovascular Sciences, University College London, London WC1E 6JJ, UK. 9. European Molecular Biology Laboratory, European Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK. 10. Department of Mathematical and Statistical Sciences, University of Colorado, Denver CO 80202, USA. 11. Departments of Medicine & Human Genetics, McGill University, Montreal, Quebec, Canada. 12. The Genome Centre, John Vane Science Centre, Queen Mary, University of London, Charterhouse Square, London EC1M 6BQ, UK. 13. University of Cambridge Metabolic Research Laboratories, and NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK. 14. University College London (UCL) Genetics Institute (UGI) Gower Street, London, WC1E 6BT, UK. 15. Department of Oncology, McGill University, Montreal, Quebec, Canada. 16. BGI-Shenzhen, Shenzhen 518083, China. 17. Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen, Denmark. 18. BGI-Europe, London. 19. Princess Al Jawhara Albrahim Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia; 20. Macau University of Science and Technology, Avenida Wai long, Taipa, Macau 999078, China; 21. Department of Medicine and State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, 21 Sassoon Road, Hong Kong 22. Department of Haematology, University of Cambridge, Long Road, Cambridge CB2 0PT, UK. 23. & Genomics, Biogen Idec, 14 Cambridge Center, Cambridge, MA02142, USA. 24. Department of Medical and Molecular Genetics, Division of Genetics and Molecular Medicine, King's College London School of Medicine, Guy's Hospital, London SE1 9RT, UK. 25. University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia 26. Adaptive Biotechnologies Corporation, Seattle, WA, USA. 27. Human Genetics Research Centre, St George's University of London, UK. 28. Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston MA 02114, USA. 29. Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, OX3 7BN, UK. 30. Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge MA 02132, USA. 31. Department of Statistics, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, UK. 32. Department of Genetics, Harvard Medical School, Boston 02115, USA. 33. The Department of Epidemiology and Biostatistics, Imperial College London, St. Mary’s campus, Norfolk Place, Paddington, London W2 1PG, UK. 34. ALSPAC School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Clifton, Bristol, BS8 2BN, UK. 35. Departments of Health Sciences and Genetics, University of Leicester, Leicester, UK. 36. School of Oral and Dental Sciences, University of Bristol, Lower Maudlin Street, Bristol, BS1 2LY, UK 37. School of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol, BS8 1TU, UK. 38. National Institute for Health Research (NIHR) Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, Leicester, UK. 39. Queensland Brain Institute, University of Queensland, Brisbane, Queensland 4072, Australia. 40. School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia. 41. Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia. 42. Department of Psychiatry, Trinity Centre for Health Sciences, St. James Hospital, James's Street, Dublin 8, Ireland. 43. Division of Developmental Disabilities, Department of Psychiatry, Queen's University, Kingston, Canada 44. Division of Psychiatry, The University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, EH10 5HF, UK. 45. Institute of Psychiatry, Kings College London, 16 De Crespigny Park, London SE5 8AF, UK. 46. NIHR BRC for Mental Health, Institute of Psychiatry and SLaM NHS Trust, King's College London, 16 De Crespigny Park, London SE5 8AF, UK. 47. Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, Denmark Hill, London, SE5 8AF, UK. 48. Lilly Research Laboratories, Eli Lilly & Co. Ltd., Erl Wood Manor, Sunninghill Road, Windlesham, Surrey, UK. 49. MRC Centre for Neuropsychiatric Genetics & Genomics, Institute of Psychological Medicine & Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, CF14 4XN. 50. University of Sussex, Brighton BN1 9RH, UK. 51. Sussex Partnership NHS Foundation Trust, Swandean, Arundel Road, Worthing, West Sussex, BN13 3EP, UK. 52. University College London (UCL), Molecular Psychiatry Laboratory, Division of Psychiatry, Gower Street, London WC1E 6BT, UK. 53. UCLA David Geffen School of Medicine, Los Angeles, California, USA. 54. Behavioural and Brain Sciences Unit, UCL Institute of Child Health, London, WC1N 1EH, UK. 55. National Institute for Health and Welfare (THL), Helsinki. 56. The Patrick Wild Centre, The University of Edinburgh, Edinburgh, EH10 5HF, UK 57. Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland. 58. Program in Medical and Population Genetics and Genetic Analysis Platform, The Broad Institute of MIT and Harvard, Cambridge, MA 02132, USA. 59. Institute of Neuroscience, Henry Wellcome Building for Neuroecology, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK. 60. University of Helsinki, Department of Psychiatry, Helsinki. 61. Institute of Medical Sciences, University of Aberdeen, AB25 2ZD, UK. 62. Department of Pathology, King Abdulaziz Medical City, Riyadh, Saudi Arabia. 63. Genetics and Genomic Medicine and Birth Defects Research Centre, UCL Institute of Child Health, London, WC1N 1EH, UK. 64. Department of Cardiovascular Medicine and Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, OX3 7BN, UK. 65. Dubowitz Neuromuscular Centre, UCL Institute of Child Health & Great Ormond Street Hospital, London, WC1N 1EH, UK. 66. Institut für Humangenetik, Uniklinik Köln, Kerpener Str. 34, 50931 Köln, Germany. 67. MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, at the University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK. 68. Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, CB2 0XY, UK. 69. Department of Mathematics, Université de Québec À Montréal, Montréal, Québec, Canada. 70. HeLEX – Centre for Health, Law and Emerging Technologies, Department of Public Health, University of Oxford, Old Road Campus, Oxford, OX3 7LF, UK. 71. Genetic Alliance UK, 4D Leroy House, 436 Essex Road, London N1 3QP, UK. 72. Yorkshire Regional Genetics Service, St James University Hospital, Beckett Street, Leeds, West Yorkshire, LS9 7TF, UK. 73. University College London (UCL) Department of Genetics, Evolution & Environment (GEE), Gower Street, London WC1E 6BT, UK 74. SW Thames Regional Genetics Lab, St George’s University, Cranmer Terrace, London SW17 0RE, UK 75. Institute of Cardiovascular Science, University College London, Gower Street, London, WC1E 6BT, UK. 76. Department of Genetics, Biology and Biochemistry, University of Turin, Italy 77. North West Thames Regional Genetics Service, Kennedy-Galton Centre, Northwick Park Hospital, Watford Road, Harrow, HA1 3UJ, UK 78. Connective Tissue Disorders Service, Sheffield Diagnostic Genetics Service, Sheffield Children's NHS Foundation Trust, Western Bank, Sheffield, S10 2TH, UK. 79. Molecular Genetics, Viapath at Guy's Hospital, London, SE1 9RT 80. Molecular Genetics, St George’s Hospital, Blackshaw Road, London SW17 0QT, UK 81. Clinical Genetics, Guy's & St Thomas' NHS Foundation Trust, London, SE1 9RT 82. Ehlers-Danlos Syndrome National Diagnostic Service, North West London Hospitals NHS Trust, Harrow, Middlesex, United Kingdom 83. Merck Sharp Dohm R&D (China) Co. Ltd., 2F Building 21, 22 Universal Business Park, No 10, Jiuxianqiao Road, Chaoyang District, Beijing 10001, P. R. China