GLYCOL ETHERS (Cellosolves®)

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GLYCOL ETHERS (Cellosolves®) Glycol ethers have many uses; these include use as solvents and as an ingredient in cleaning compounds, liquid soaps, and cosmetics. Acute (short-term) exposure to high levels of the glycol ethers in humans results in narcosis, pulmonary edema, and severe liver and kidney damage. It is also a reproductive hazard. List of Glycol Ethers Ethylene glycol ethyl ether (EGEE, ethylene glycol monoethyl ether, ethoxyethanol, Cellosolve®) Ethylene glycol ethyl ether acetate (EGEEA, ethylene glycol monoethyl ether acetate, ethoxyethanol acetate, Cellosolve Acetate®) Ethylene glycol methyl ether (EGME, ethylene glycol monomethyl ether, methoxyethanol, Methyl Cellosolve®) Ethylene glycol methyl ether acetate (EGMEA, ethylene glycol monomethyl ether acetate, methoxyethanol acetate, Methyl Cellosolve Acetate®) Ethylene glycol dimethyl ether (EGDME) Ethylene glycol diethyl ether (EGDEE) Diethylene glycol dimethyl ether (DEGDME) Diethylene glycol diethyl ether (DEGDEE) Triethylene glycol dimethyl ether (TEGDME) Hazards of Listed Glycol Ethers Reproductive and developmental toxicity is based on results of animal studies. Recent studies in the semi-conductor industry indicate that these glycol ethers could have similar effects at very low exposure levels in humans Safety Practices Use heavy butyl rubber gloves to prevent skin contact Keep the material covered and work in a hood to prevent respiratory exposure Review the Safety Data Sheet (SDS) prior to working with glycol ethers Call EH&S at 951-827-5528 prior to working with glycol ethers for assistance in developing safety practices For more information please visit www.ehs.ucr.edu or call 951-827-5528. A Message brought to you by www.ehs.ucr.edu .

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The Toxicology of Glycol Ethers and Its Relevance to Man (Fourth Edition) Volume I
The Toxicology of Glycol Ethers and its Relevance to Man (Fourth Edition) Volume I Technical Report No. 95 ISSN-0773-8072-95 Brussels, February 2005 The Toxicology of Glycol Ethers and its Relevance to Man ECETOC TECHNICAL REPORT No. 95 © Copyright – ECETOC AISBL European Centre for Ecotoxicology and Toxicology of Chemicals 4 Avenue E. Van Nieuwenhuyse (Bte 6), B-1160 Brussels, Belgium. All rights reserved. No part of this publication may be reproduced, copied, stored in a retrieval system or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the copyright holder. Applications to reproduce, store, copy or translate should be made to the Secretary General. ECETOC welcomes such applications. Reference to the document, its title and summary may be copied or abstracted in data retrieval systems without subsequent reference. The content of this document has been prepared and reviewed by experts on behalf of ECETOC with all possible care and from the available scientific information. It is provided for information only. ECETOC cannot accept any responsibility or liability and does not provide a warranty for any use or interpretation of the material contained in the publication. ECETOC TR No. 95 The Toxicology of Glycol Ethers and its Relevance to Man The Toxicology of Glycol Ethers and its Relevance to Man CONTENTS - VOLUMES I AND II EXECUTIVE SUMMARY 1 SUMMARY AND CONCLUSIONS 3 Recommendations for further work 13 1. INTRODUCTION 14 1.1 Conversion factors and physico-chemical properties 14 1.2 Production and use 14 1.2.1 Manufacture of ethylene-series glycol ethers 14 1.2.2 Manufacture of propylene-series glycol ethers 15 1.2.3 Uses 15 2.
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GLYCOL ETHERS 273-328.Qxp 13/12/2006 12:02 Page 328 329-414.Qxp 13/12/2006 12:21 Page 329
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